Effects of Late Pleistocene Climatic Fluctuations on the Phylogeographic and Demographic History of Japanese Scad (Decapterus maruadsi) - Qing-Hua Wang; Ren-Xie Wu; Zhong-Lu Li; Su-Fang Niu; Yun Zhai; Min Huang; Biao Li (Frontiers in Marine Science, 2022)
The Late Pleistocene-Holocene climate fluctuations have greatly influenced the phylogeographic structure and historical dynamics of many marine organisms in the western Pacific marginal seas. Here, we investigated the impact of Pleistocene glacial-interglacial cycles on the phylogeographic structure and demographic dynamics of Decapterus maruadsi , an economically important fish along the coast of the East China Sea (ECS) and northern South China Sea (NSCS). We obtained 430 concatenated sequences (Cyt b + control region, 1548–1554 bp) of D. maruadsi , including 246 newly sampled from the ECS and 184 previously determined from the NSCS. Genetic structure and phylogenetic analysis demonstrated a lack of significant population structure among 16 populations. Moreover, there was no significant differentiation among populations from Chinese coastal waters and northern Vietnam. Neutrality tests, unimodal mismatch distributions, Bayesian skyline plots, and the star-like haplotype networks all indicated a recent demographic expansion for D. maruadsi population during the Late Pleistocene-Holocene, explaining the low genetic diversity in D. maruadsi along the southeast coast of China. Notably, phylogenetic analyses and net genetic distances based on Cyt b jointly confirmed that 57 Cyt b haplotypes identified as D. maruadsi from the previously defined Sundaland-Rosario-Ranong clade actually represented D. russelli . These results not only reveal the complex effects of Pleistocene-Holocene climate fluctuations on the phylogeographic structure and demographic history of D. maruadsi but also provide useful genetic information for the management of genetic resources.

The association of cerebrospinal fluid pressure with optic nerve head and macular vessel density - Xiangxiang Liu; Mohamed M. Khodeiry; Danting Lin; Yunxiao Sun; Qing Zhang; Jiawei Wang; Richard K. Lee; Ningli Wang (Science China Life Sciences, 2022)

Damage Evolution Laws of Low-Strength Molybdenum Ore Under Uniaxial Compression - Jian Yang; Kang Zhao; Yufeng Song; Qing Wang; Kangqi Zhao; Yongbo Ji (Natural Resources Research, 2022)

Research on Ecological Security of Shengjin Lake Wetland (Anhui Province of China) Based on TM Images - Zhili Xu; Bin Dong; Xiang Gao; Ping Wang; Qing Wang; Sheng Li; Haifeng Xu; Yaru Liu; Tong Wang; Chunqiu Ren (Journal of the Indian Society of Remote Sensing, 2022)

Numerical simulation of the Rongcharong paleolandslide river-blocking event: implication for the longevity of the landslide dam - Jianhua Yan; Jianping Chen; Fujun Zhou; Yongchao Li; Yiwei Zhang; Feifan Gu; Yansong Zhang; Yuchao Li; Zhihai Li; Yiding Bao; Qing Wang (Landslides, 2022)

Life cycle assessment of rice bran oil production: a case study in China - Li-Hui Sun; Yu-Ying Wang; Yu-Qing Gong (Environmental Science and Pollution Research, 2022)

Preparation of formate-free PMA@MOF-808 catalysts for deep oxidative desulfurization of model fuels - Cheng Wang; Airong Li; Yuling Ma; Shenglan Qing (Environmental Science and Pollution Research, 2022)

Analysis of the spatial distribution and influencing factors of China national forest villages - Guofang Gong; Zhen Wei; Fengtai Zhang; Yuzhen Li; Youzhi An; Qing Yang; Jianfeng Wu; Lu Wang; Pengzhen Yu (Environmental Monitoring and Assessment, 2022)

Lithology identification of logging data based on improved neighborhood rough set and AdaBoost - Xialin Zhang; Qing Sun; Kunyang He; Zhenjiang Wang; Jin Wang (Earth Science Informatics, 2022)

Deciphering the variations and mechanisms of the westerly jets across the Northern Hemisphere during the Last Interglacial based on PMIP4 models - Nanxuan Jiang; Qing Yan; Huijun Wang (Climate Dynamics, 2022)

Task-related connectivity of decision points during spatial navigation in a schematic map - Qing Qi; Yihe Weng; Senning Zheng; Shuai Wang; Siqi Liu; Qinda Huang; Ruiwang Huang (Brain Structure and Function, 2022)

Invasibility and recoverability of a plant community following invasion depend on its successional stages - Hongwei Xu; Zemin Ai; Qing Qu; Minggang Wang; Guobin Liu; Sha Xue (Soil Ecology Letters, 2022)

Electrical resistivity imaging in Shibaozhai area using magnetotelluric sounding: Enlightenment of hydrocarbon reservoirs on the eastern edge of the Sichuan Basin - Shu-Ming Wang; Qing-Yun Di; Gui-An Zou; Xiao-Lu Su; Cai Qian; Ruo Wang; De-Shan Li (Applied Geophysics, 2022)

Double-phase-shift filtering method for harmonic elimination based on AR2U-Net - Bo-Lin Li; Yan-Chun Wang; Hang Yuan; Xue-Qing Liu (Applied Geophysics, 2022)

Expanding the clinical spectrum of adult-onset neuronal intranuclear inclusion disease - Yuwen Cao; Jingying Wu; Yunhua Yue; Chao Zhang; Shihua Liu; Ping Zhong; Shige Wang; Xiaojun Huang; Weiping Deng; Jing Pan; Lan Zheng; Qing Liu; et al. (Acta Neurologica Belgica, 2022)

Anti-hyperglycaemic effect of labdane diterpenes isolated from the rhizome of Amomum maximum Roxb., an edible plant in Southwest China - Chuan-Li Lu; Li-Ning Wang; Ya-Jun Li; Qing-Fei Fan; Qing-Hua Huang; Jun-Jia Chen (Natural Product Research, 2022)

Comparative Analysis of Pseudo-nitzschia Chloroplast Genomes Revealed Extensive Inverted Region Variation and Pseudo-nitzschia Speciation - Ziyan He; Yang Chen; Yichao Wang; Kuiyan Liu; Qing Xu; Yang Li; Nansheng Chen (Frontiers in Marine Science, 2022)
Pseudo-nitzschia is a species-rich genus where many species can induce harmful algae blooms (HABs) associated with the toxin domoic acid (DA) production. Despite the importance of Pseudo-nitzschia species to coastal environments, their genomic information is rather limited, hindering research on biodiversity and evolutionary analysis. In this study, we report full-length chloroplast genomes (cpDNAs) of nine Pseudo‐nitzschia , among which cpDNAs of eight Pseudo-nitzschia species were reported for the first time. The sizes of these Pseudo-nitzschia cpDNAs, which showed typical quadripartite structures, varied substantially, ranging from 116,546 bp to 158,840 bp in size. Comparative analysis revealed the loss of photosynthesis-related gene psaE in cpDNAs of all Pseudo-nitzschia species except that of P. americana , and the selective loss of rpl36 in P. hainanensis . Phylogenetic analysis showed that all Pseudo-nitzschia strains were grouped into two clades, with clade 1 containing cpDNAs of P. multiseries , P. pungens , P. multistriata , and P. americana , and clade 2 containing cpDNAs of P. hainanensis , P. cuspidata , Pseudo-nitzschia sp. CNS00097, P. delicatissima , and P. micropora . The small size of the P. americana cpDNA was primarily due to its shortened inverted repeat (IR) regions. While psaA and psaB were found in the IR regions of cpDNAs of other eight species, these two genes were found outside of the IR regions of P. americana cpDNA. In contrast, P. hainanensis had the largest size because of expansion of IR regions with each IR region containing 15 protein-coding genes (PCGs). Eleven genetic regions of these Pseudo-nitzschia cpDNAs exhibited high nucleotide diversity (Pi) values, suggesting that these regions may be used as molecular markers for distinguishing different Pseudo-nitzschia species with high resolution and high specificity. Phylogenetic analysis of the divergence of nine Pseudo-nitzschia species indicated that these species appeared at approximately 41 Mya. This study provides critical cpDNA resources for future research on the biodiversity and speciation of Pseudo-nitzschia species.

A new highly oxygenated germacranolide from Carpesium nepalense var. lanatum (C.B.Clarke) Kitam - Yi-Fan Yu; Yue-Qian Li; Ru-Yue Wang; Xu Liu; Wen-Bo Cui; Xiao-Han Chen; Cheng-Mu Zhao; Feng-Ming Qi; Zhan-Xin Zhang; Dong-Qing Fei (Natural Product Research, 2022)

Secoiridoid glycosides from the fruits of Cornus officinalis - Xin Wang; Xiang-Jian Zhong; Na Zhou; Lin-Lin Ji; Jin-Jie Li; Ning Cai; Qing-Bo Wang; Peng-Cheng Lin; Xiao-Ya Shang (Natural Product Research, 2022)

PdeHCA2 affects biomass in Populus by regulating plant architecture, the transition from primary to secondary growth, and photosynthesis - Biligen-Gaowa Zhao; Guo Li; Yue-Feng Wang; Zhen Yan; Feng-Qin Dong; Ying-Chang Mei; Wei Zeng; Meng-Zhu Lu; Hong-Bin Li; Qing Chao; Bai-Chen Wang (Planta, 2022)

Mutation of Beclin1 acetylation site at K414 alleviates high glucose-induced podocyte impairment in the early stage of diabetic nephropathy by inhibiting hyperactivated autophagy - Jun Xu; Yujie Deng; Yingying Ke; Yunxia Zhu; Ping Wang; Qing Yu; Chengqian Li; Bimin Shi (Molecular Biology Reports, 2022)

Genome-wide association analysis discovered new loci and candidate genes associated with low-phosphorus tolerance based on shoot mineral elements concentrations in soybean - Qing Wang; Wenkai Du; Wenqing Yu; Weihao Zhang; Fang Huang; Hao Cheng; Deyue Yu (Molecular Genetics and Genomics, 2022)

Hyperlipidemia patients carrying LDLR splicing mutation c.1187-2A>G respond favorably to rosuvastatin and PCSK9 inhibitor evolocumab - Xiaoyu Zhang; Qianqian Liu; Hongfu Zhang; Chengcheng Tan; Qiangfeng Zhu; Saiyong Chen; Yinglong Du; Haitao Yang; Qingli Li; Chengqi Xu; Chun Wu; Qing K. Wang (Molecular Genetics and Genomics, 2022)

miR-155 activates the NLRP3 inflammasome by regulating the MEK/ERK/NF-κB pathway in carotid atherosclerotic plaques in ApoE−/− mice - Qing Peng; Ruihua Yin; Xiaoyan Zhu; Liying Jin; Jing Wang; Xudong Pan; Aijun Ma (Journal of Physiology and Biochemistry, 2022)

MiR-1260b protects against LPS-induced degenerative changes in nucleus pulposus cells through targeting TCF7L2 - Shijie Chen; Guixia Shi; Jin Zeng; Ping Huang Li; Yi Peng; Zhiyu Ding; Hong Qing Cao; Ruping Zheng; Weiguo Wang (Human Cell, 2022)

Responses of photosynthesis, antioxidant enzymes, and related gene expression to nicosulfuron stress in sweet maize (Zea mays L.) - Zhen-Xing Wu; Ning-Wei Xu; Min Yang; Xiang-Ling Li; Jin-Ling Han; Xiao-Hu Lin; Qing Yang; Gui-Hua Lv; Jian Wang (Environmental Science and Pollution Research, 2022)

The dynamic behavior of calcareous sand under actual seismic loading - Hai-Ping Wang; Meng Gao; Ying Wang; Qing-Sheng Chen (Arabian Journal of Geosciences, 2022)

Geochronology and geochemistry of Late Triassic intrusions in the Liaodong Peninsula, eastern North China Craton: implications for post-collisional lithospheric thinning - Chen Wang; Zheng-Hong Liu; Gang Li; Xiao-Jie Dong; Shi-Chao Li; Qing-Ying Zhao (International Geology Review, 2022)

Decision-Making on the Selection of Clean Energy Technology for Green Ships Based on the Rough Set and TOPSIS Method - Huihui Xuan; Qing Liu; Lei Wang; Liu Yang (Journal of Marine Science and Engineering, 2022)
In the context of the decarbonization of the shipping industry, the application of clean energy technologies is a catalyst for decarbonization. With the number of potential clean energy technologies expanding, the uncertainties in terms of technology maturity, policy regulation, and economics make clean energy technologies decision much more difficult. Therefore, it is urgent to establish a clean energy technology selection scenario for the green ship industry to assist shipowners in decision-making. Based on this, a technology selection model based on rough set (RS) and approximate ideal solution ranking (TOPSIS) is constructed. Using RS to reduce the evaluation index and calculate the weight can avoid the one-sidedness of subjective weighting. Using the TOPSIS method to rank alternatives. This paper selects seven clean energy technology alternatives, namely LNG power, LPG power, methanol power, HVO power, pure battery power, hydrogen fuel cell, and ammonia fuel cell, respectively, as the evaluation objects. Taking two types of vessels as examples, it is concluded that LNG power technology is suitable for large coastal ro-ro passenger vessels, and pure battery power technology is suitable for small inland river short-distances vessels. The results are in line with reality, which verifies the scientificity and validity of the proposed model.

Three new C 21 steroidal glycosides isolated from Metaplexis japonica and their potential inhibitory effects on tyrosine protein kinases - Xu Wang; Qing-Yun Ma; Chen Liu; Jia Yang; Qing-Tao Lv; Zhen-Hua Tian; Hai-Qiang Jiang; Rong Rong (Natural Product Research, 2022)

Berberisides A-D: three novel prenylated benzoic acid derivatives and a clerodane glycoside from Berberis tsarica aherndt. - Zhao-Yue Dong; Qing-Hong Zeng; Lin Wei; Xin Guo; Yan Sun; Fan-Cheng Meng; Guo-Wei Wang; Xiao-Zhong Lan; Zhi-Hua Liao; Min Chen (Natural Product Research, 2022)

DSRD: deep sparse representation with learnable dictionary for remotely sensed image denoising - Zhenghua Huang; Zhicheng Wang; Qian Li; Junbo Chen; Yaozong Zhang; Hao Fang; Qing An (International Journal of Remote Sensing, 2022)

A Novel Mutation in COL4A1 Gene in a Chinese Family with Pontine Autosomal Dominant Microangiopathy and Leukoencephalopathy - Qing Li; Chengfeng Wang; Wei Li; Zaiqiang Zhang; Shanshan Wang; Autongsha Wupuer; Xiao Hu; Kalibinuer Wumaier; Yi Zhu; Hongyan Li; Wengui Yu (Translational Stroke Research, 2022)
Pontine autosomal dominant microangiopathy and leukoencephalopathy (PADMAL) is a rare hereditary cerebral small vessel disease. We report a novel collagen type IV alpha 1 ( COL4A1 ) gene mutation in a Chinese family with PADMAL. The index case was followed up for 6 years. Neuroimaging, whole-exome sequencing, skin biopsy, and pedigree analysis were performed. She initially presented with minor head injury at age 38. MRI brain showed chronic lacunar infarcts in the pons, left thalamus, and right centrum semiovale. Extensive workup was unremarkable except for a patent foramen ovale (PFO). Despite anticoagulation, PFO closure, and antiplatelet therapy, the patient had recurrent lacunar infarcts in the pons and deep white matter, as well as subcortical microhemorrhages. Whole-exome sequencing demonstrated a novel c.*34G > T mutation in the 3′ untranslated region of COL4A1 gene. Skin biopsy subsequently demonstrated thickening of vascular basement membrane, proliferation of endothelial cells, and stenosis of vascular lumen. Three additional family members had gene testing and 2 of them were found to have the same heterozygous mutation. Of the 18 individuals in the pedigree of 3 generations, 12 had clinical and MRI evidence of PADMAL. The mechanisms of both ischemic and hemorrhagic stroke are likely the overexpression of COLT4A1 in the basement membrane and frugality of the vessel walls. Our findings suggest that the novel c.*34G > T mutation appears to have the same functional consequences as the previously reported COL4A1 gene mutations in patients with PADMAL and multi-infarct dementia of Swedish type.

Survey of Road Extraction Methods in Remote Sensing Images Based on Deep Learning - Pengfei Liu; Qing Wang; Gaochao Yang; Lu Li; Huan Zhang (PFG – Journal of Photogrammetry, Remote Sensing and Geoinformation Science, 2022)

Complete chloroplast genome of Campsis grandiflora (Thunb.) schum and systematic and comparative analysis within the family Bignoniaceae - Haimei Chen; Zhuoer Chen; Qing Du; Mei Jiang; Bin Wang; Chang Liu (Molecular Biology Reports, 2022)

The complete chloroplast genome sequence of Clerodendranthus spicatus, a medicinal plant for preventing and treating kidney diseases from Lamiaceae family - Qing Du; Mei Jiang; Sihui Sun; Liqiang Wang; Shengyu Liu; Chuanbei Jiang; Haidong Gao; Haimei Chen; Yong Li; Bin Wang; Chang Liu (Molecular Biology Reports, 2022)

Cassiterite oxygen isotopes in magmatic-hydrothermal systems: in situ microanalysis, fractionation factor, and applications - Yang Li; Sheng He; Rong-Qing Zhang; Xian-Wu Bi; Lian-Jun Feng; Guo-Qiang Tang; Wen-Zhong Wang; Fang Huang; Xian-Hua Li (Mineralium Deposita, 2022)

Paeoniflorin ameliorates cognitive impairment in Parkinson’s disease via JNK/p53 signaling - Zhu-qing He; Peng-fei Huan; Li Wang; Jian-cheng He (Metabolic Brain Disease, 2022)
Paeoniflorin (PF) has numerous benefits, including anti-inflammatory and anti-apoptosis effects. However, it is not clear if it has neuroprotective effects against cognitive impairment (CI) in Parkinson’s disease (PD). Through network pharmacology, we identified probable targets as well as signal pathways through which PF might affect CI in PD. Then, we experimentally validated our findings. The core genes of the protein-protein interactions (PPI) network include MAPK8 (JNK), TP53, CASP3 (caspase-3), postsynaptic density protein-95 (PSD-95) and synaptophysin (SYN). Pathway enrichment analysis revealed that genes involved in apoptosis and mitogen-activated protein kinase (MAPK) signaling were significantly enriched. Because JNK is a key mediator of p53-induced apoptosis, we wondered if JNK/p53 pathway influences the effects of PF against apoptosis in mouse model of PD. Molecular docking analysis showed that PF had good affinity for JNK/p53. The results of the experiments indicated that PF ameliorated behavioral impairments and upregulated the expression of the dopamine (DA) neurons, suppressed cell apoptosis in substantia nigra pars compacta (SNpc) of PD. Additionally, PF improved 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neuronal injury by inhibiting apoptosis in hippocampal neurons of the CA1 and CA3, and upregulating PSD-95 as well as SYN protein levels. Similar protective effects were observed upon JNK/p53 pathway inhibition using SP600125. Overall, PF improved CI in PD by inhibiting JNK/p53 pathway.

Liposome-Encapsulated Rec8 and Dmrt1 Plasmids Induce Red-Spotted Grouper (Epinephelus akaara) Testis Maturation - Xuzhuo Duan; Xianze Jia; Kaishan Liang; Fengqi Huang; Jinhong Shan; Huitao Chen; Xinhe Ruan; Lihua Li; Huihong Zhao; Qing Wang (Marine Biotechnology, 2022)

Comparative metabolomics provides novel insights into the basis of petiole color differences in celery (Apium graveolens L.) - Mengyao Li; Jie Li; Haohan Tan; Ya Luo; Yong Zhang; Qing Chen; Yan Wang; Yuanxiu Lin; Yunting Zhang; Xiaorong Wang; Haoru Tang (Journal of Zhejiang University-SCIENCE B, 2022)

Combined numerical investigation of the Gangda paleolandslide runout and associated dam breach flood propagation in the upper Jinsha River, SE Tibetan Plateau - Yansong Zhang; Jianping Chen; Fujun Zhou; Yiding Bao; Jianhua Yan; Yiwei Zhang; Yongchao Li; Feifan Gu; Qing Wang (Landslides, 2022)

Short-term effect of ambient air pollutant change on the risk of tuberculosis outpatient visits: a time-series study in Fuyang, China - Xin-Qiang Wang; Ying-Qing Li; Cheng-Yang Hu; Kai Huang; Kun Ding; Xiao-Jing Yang; Xin Cheng; Kang-Di Zhang; Wen-Jie Yu; Jie Wang; Yong-Zhong Zhang; Zhen-tao Ding; et al. (Environmental Science and Pollution Research, 2022)

Dynamics of nitrogen and phosphorus profile and its driving forces in a subtropical deep reservoir - Cunli Li; Ping Zhang; Guangwei Zhu; Chao Chen; Yucheng Wang; Mengyuan Zhu; Hai Xu; Cuiling Jiang; Wei Zou; Pengcheng Shi; Qing Zheng (Environmental Science and Pollution Research, 2022)

Production of sesquiterpene patchoulol in mitochondrion-engineered Saccharomyces cerevisiae - Xin-Yi Tao; Yang-Chen Lin; Feng-Qing Wang; Qing-Hai Liu; Yu-Shu Ma; Min Liu; Dong-Zhi Wei (Biotechnology Letters, 2022)

Orexin A peptidergic system: comparative sleep behavior, morphology and population in brains between wild type and Alzheimer’s disease mice - Peng Zhao; Yaqian You; Zhe Wang; Yanjun Zhou; Gaoshang Chai; Gen Yan; Zhewu Jin; Qing Wang; Hongxu Sun (Brain Structure and Function, 2022)
Sleep disturbance is common in patients with Alzheimer’s disease (AD), and orexin A is a pivotal neurotransmitter for bidirectionally regulating the amyloid-β (Aβ) deposition of AD brain and poor sleep. In the present study, we examined the characteristic of sleep–wake architecture in APPswe/PSldE9 (APP/PS1) and Aβ-treated mice using electroencephalogram (EEG) and electromyographic (EMG) analysis. We compared the expression of orexin A, distribution, and morphology of the corresponding orexin A-positive neurons using innovative methods including three-dimensional reconstruction and brain tissue clearing between wild type (WT) and APP/PS1 mice. Results from our study demonstrated that increased wakefulness and reduced NREM sleep were seen in APP/PS1 and Aβ treated mice, while the expression of orexin A was significantly upregulated. Higher density and distribution of orexin A-positive neurons were seen in APP/PS1 mice, with a location of 1.06 mm–2.30 mm away from the anterior fontanelle compared to 1.34 mm–2.18 mm away from the anterior fontanelle in WT mice. These results suggested that the population and distribution of orexin A may play an important role in the progression of AD.

The altered functional modular organization in systemic lupus erythematosus: an independent component analysis study - Zheng-Ye Cao; Na Wang; Hua Wei; Jie-Ting Jia; Hong-Ying Zhang; Song-An Shang; Qing-Qiang Zhu; Xian-Fu Luo; Jing-Tao Wu (Brain Imaging and Behavior, 2022)

Effect of the Grain for Green Project on freshwater ecosystem services under drought stress - Hui-qing Han; Jian-qiang Yang; Yue Liu; Ying-jia Zhang; Jun-wen Wang (Journal of Mountain Science, 2022)

Characteristics of circRNAs expression profiles in the piglets intestine induced by oxidative stress - Zhi-xin Li; Wei Chen; Ming Qin; Li-xue Wang; Yong-qing Zeng (Genes & Genomics, 2022)

Imatinib-induced hepatotoxicity via oxidative stress and activation of NLRP3 inflammasome: an in vitro and in vivo study - Feng-Ru Huang; Wen-Tong Fang; Zi-Ping Cheng; Ye Shen; Dun-Jian Wang; Yong-Qing Wang; Lu-Ning Sun (Archives of Toxicology, 2022)

Four new resorcinol derivatives with neuroprotective activities from Xylaria nigripes - Lan-Qing Li; Jing Li; Hong-Ping Long; Ji-Kai Liu; Xian Wang (Natural Product Research, 2022)

Sophoranone A and B: two new cytotoxic prenylated metabolites and their analogs from the root bark of Sophora flavescens - Guo-Qing Long; Gao-Sheng Hu; Xiao-Xu Gao; Jing-Ming Jia; An-Hua Wang (Natural Product Research, 2022)

Structure, antioxidant property and protection on PC12 of a polysaccharide isolated and screened from Abelmoschus esculentus L.Moench (okra) - Li-Chao Pan; Yang-Yang Sun; Xiao-Ling Zhang; Zhen-Yuan Zhu; Chun-Yu Liu; Hui-Qing Sun; Xue-Qing Geng; Wei Jiang; Jia-He Wang (Natural Product Research, 2022)

Bioactive isocoumarins isolated from a mangrove-derived fungus Penicillium sp. MGP11 - Rong-Qing Mei; Bin Wang; Wei-Nv Zeng; Guo-Lei Huang; Guang-Ying Chen; Cai-Juan Zheng (Natural Product Research, 2022)

Diketopiperazine and enterotoxin analogues from the mangrove derived-soil Streptomyces sp. SCSIO 41400 and their biological evaluation - Meng-Meng Song; Yu-Hui Xie; Wei-Hao Chen; Yi-Wei Hu; Kai Zhao; Yong-Hong Liu; Xiao-Long Huang; Qing-Chao Liu; Jun-Feng Wang (Natural Product Research, 2022)

Effects of Drying-Flooding Alternation on Sediment–Water Nitrogen Fluxes in Hydro-fluctuation Belt of the Danjiangkou Reservoir - Han Wang; Qing Wu; Yuping Han (Water, Air, & Soil Pollution, 2022)

Punicalagin ameliorates collagen-induced arthritis by downregulating M1 macrophage and pyroptosis via NF-κB signaling pathway - Gaoran Ge; Jiaxiang Bai; Qing Wang; Xiaolong Liang; Huaqiang Tao; Hao Chen; Minggang Wei; Junjie Niu; Huilin Yang; Yaozeng Xu; Yuefeng Hao; Yi Xue; et al. (Science China Life Sciences, 2022)

Progressive Failure of Blocky Rock System: Geometrical–Mechanical Identification and Rock-Bolt Support - Qi-Hua Zhang; Qing-Bing Liu; Shu-Hong Wang; Hong-Liang Liu; Gen-Hua Shi (Rock Mechanics and Rock Engineering, 2022)

Hippocampal SIRT1-Mediated Synaptic Plasticity and Glutamatergic Neuronal Excitability Are Involved in Prolonged Cognitive Dysfunction of Neonatal Rats Exposed to Propofol - Lin-Hui Ma; Jie Wan; Jing Yan; Ning Wang; Yan-Ping Liu; Hai-Bi Wang; Cheng-Hua Zhou; Yu-Qing Wu (Molecular Neurobiology, 2022)

Whole genome re-sequencing reveals the genetic diversity and evolutionary patterns of Eucommia ulmoides - Jun Qing; Yi-De Meng; Feng He; Qing-Xin Du; Jian Zhong; Hong-Yan Du; Pan-Feng Liu; Lan-Ying Du; Lu Wang (Molecular Genetics and Genomics, 2022)

LncRNA CEBPA-AS1 knockdown prevents neuronal apoptosis against oxygen glucose deprivation/reoxygenation by regulating the miR-455/GPER1 axis - Jun Peng; Zheng-Tao Yu; Rong-Jun Xiao; Qing-Song Wang; Ying Xia (Metabolic Brain Disease, 2022)

Impact of ocean acidification on physiology and microbiota in hepatopancreas of Pacific oyster Crassostrea gigas - Lingshuai Zhang; Xiudan Wang; Weiqian Zhang; Xiaoting Yin; Qing Liu; Limei Qiu (Journal of Oceanology and Limnology, 2022)

Zinc finger and BTB domain-containing protein 20 aggravates angiotensin II-induced cardiac remodeling via the EGFR-AKT pathway - Fangfang Li; Miaomiao Du; Yiming Yang; Zhu Wang; Hu Zhang; Xiaoyu Wang; Qing Li (Journal of Molecular Medicine, 2022)

The effect of preoperative statin treatment on acute kidney injury in elderly patients undergoing valve replacement surgery - Bing-qi Fu; Xue-biao Wei; Zedazhong Su; Ying-wen Lin; Zu-hui Ke; Tong Tan; Ji-yan Chen; Shou-hong Wang; Dan-qing Yu (European Journal of Clinical Pharmacology, 2022)

Identification of epigenetic modifications mediating the antagonistic effect of selenium against cadmium-induced breast carcinogenesis - Zhuo-Zhi Liang; Yi-Xin Zhang; Rui-Mei Zhu; Yue-Lin Li; Hong-Mei Jiang; Ruo-Bi Li; Qian-Xin Chen; Qing Wang; Lu-Ying Tang; Ze-Fang Ren (Environmental Science and Pollution Research, 2022)

Pore-scale study on the characteristic hydraulic conductivity of a dispersive lean clay affected by salinity and freeze–thaw - Yan Han; Qing Wang; Jing Liu; Weitong Xia; Jiaqi Wang; Jiejie Shen; Yating Chen (Bulletin of Engineering Geology and the Environment, 2022)

Can artificial light promote submerged macrophyte growth in summer? - Chao Xu; Hai-Jun Wang; Yan Li; Chi Xu; Qing Yu; Miao Liu; Miao Zhang; Hong-Zhu Wang; David P. Hamilton; Erik Jeppesen (Aquatic Ecology, 2022)

Three-dimensional transformation of magnetization direction and magnetic field component at low latitudes based on vertical relationship - He Tao; Xiong Sheng-Qing; Wang Wan-Yin (Applied Geophysics, 2022)

Does the Protection of River Basin Ecosystems Produce Broken Window Effect? Evidence From Spatial Choice Experiment in Xijiang River Basin, China - Xin Nie; Zhoupeng Chen; Linfang Yang; Yiting Qing; Han Wang (Frontiers in Marine Science, 2022)
Eco-environmental protection of river basins and compensation for damages have been important issues for researchers around the world for a long time. Many studies have focused on the correlations among individual socioeconomic characteristics, ecological cognition, and differences in the willingness to pay. However, no research has been conducted from the perspective of perceived environmental quality. According to the Broken Windows Theory, the public’s willingness and behaviors regarding environmental protection are determined largely by earlier perceptions of environmental quality. Therefore, we used a spatial choice experiment to investigate the willingness of the public to pay for ecosystem restoration in the upper, middle, and lower reaches of the Xijiang River Basin in China. This paper discusses if perceived environmental quality is a factor that creates different levels in the willingness to pay. Our results show that the Broken Window Effect can better explain these differences. Living in a better ecological environment, the upper-reaches public expect to pay for the restoration of the river basin’s ecosystem to a higher state and is willing to be the “first person” to repair the “broken windows,” whereas those in the middle and lower reaches are willing to pay only for a restoration to a good state.

Gut microbiota is involved in the antidepressant effects of adipose-derived mesenchymal stem cells in chronic social defeat stress mouse model - Riyue Jiang; Yuanyuan Wang; Junbi Liu; Zifeng Wu; Di Wang; Qing Deng; Chun Yang; Qing Zhou (Psychopharmacology, 2022)

Increased abscisic acid sensitivity and drought tolerance of Arabidopsis by overexpression of poplar abscisic acid receptors - Qing Li; Qianqian Tian; Yue Zhang; Mengxue Niu; Xiaoqian Yu; Conglong Lian; Chao Liu; Hou-Ling Wang; Weilun Yin; Xinli Xia (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

Overexpression of ORX or MCH Protects Neurological Function Against Ischemic Stroke - Gang Wu; Xi’an Zhang; Shijun Li; Dan Zhou; Jie Bai; Hanxiang Wang; Qing Shu (Neurotoxicity Research, 2022)

Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative - Qi Su; Qing Wu; Kun Chen; Jingjing Wang; Ammar Sarwar; Yanmin Zhang (Molecular Biology Reports, 2022)

Cellular metabolic basis of altered immunity in the lungs of patients with COVID-19 - Shuangyan Li; Fuxiaonan Zhao; Jing Ye; Kuan Li; Qi Wang; Zhongchao Du; Qing Yue; Sisi Wang; Qi Wu; Huaiyong Chen (Medical Microbiology and Immunology, 2022)

Bioinformatics analysis of key genes and potential mechanism in cadmium-induced breast cancer progression - Fei Wu; Yangchun Zhang; Xu Chen; Yuqing Wang; Honghao Peng; Zhengbao Zhang; Ying Yang; Qing Wang (Environmental Science and Pollution Research, 2022)

Effects of air pollution and green spaces on impaired lung function in children: a case-control study - Jingwei Zhang; Yuming Wang; Lihong Feng; Changchun Hou; Qing Gu (Environmental Science and Pollution Research, 2022)

Description of different cracking processes affecting dispersive saline soil slopes subjected to the effects of frost and consequences for the stability of low slopes - Mengxia Han; Qing Wang; Yan Han; Huicheng Fu; Jiejie Shen; Yaowu Liu (Bulletin of Engineering Geology and the Environment, 2022)

Aberrant functional and effective connectivity of the frontostriatal network in unilateral acute tinnitus patients with hearing loss - Gang-Ping Zhou; Yu-Chen Chen; Wang-Wei Li; Heng-Le Wei; Yu-Sheng Yu; Qing-Qing Zhou; Xindao Yin; Yue-Jin Tao; Hong Zhang (Brain Imaging and Behavior, 2022)

Delayed body development with reduced triglycerides levels in leptin transgenic pigs - Yubo Qing; Muhammad Ameen Jamal; Dejia Shi; Sumei Zhao; Kaixiang Xu; Deling Jiao; Heng Zhao; Honghui Li; Baoyu Jia; Haizhen Wang; Hong-Ye Zhao; Hong-Jiang Wei (Transgenic Research, 2022)

Evaluation of suitable qRT-PCR normalization genes for various citrus rootstocks - Wen He; Rui Xie; Huan Li; Yan Wang; Qing Chen; Yuanxiu Lin; Yunting Zhang; Ya Luo; Yong Zhang; Haoru Tang; Xiaorong Wang (Plant Biotechnology Reports, 2022)

Infectivity and antigenicity of pseudoviruses with high-frequency mutations of SARS-CoV-2 identified in Portugal - Hai-xin Wang; Li Zhang; Zi-teng Liang; Jian-hui Nie; Jia-jing Wu; Qian-qian Li; Ru-xia Ding; Yue Zhang; Guo-qing Chen; You-chun Wang; Hui-guo Wang; Wei-jin Huang (Archives of Virology, 2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had a major impact on global human health. During the spread of SARS-CoV-2, weakened host immunity and the use of vaccines with low efficacy may result in the development of more-virulent strains or strains with resistance to existing vaccines and antibodies. The prevalence of SARS-CoV-2 mutant strains differs between regions, and this variation may have an impact on the effectiveness of vaccines. In this study, an epidemiological investigation of SARS-CoV-2 in Portugal was performed, and the VSV-ΔG-G* pseudovirus system was used to construct 12 spike protein epidemic mutants, D614G, A222V+D614G, B.1.1.7, S477N+D614G, P1162R+D614G+A222V, D839Y+D614G, L176F+D614G, B.1.1.7+L216F, B.1.1.7+M740V, B.1.258, B.1.258+L1063F, and B.1.258+N751Y. The mutant pseudoviruses were used to infect four susceptible cell lines (Huh7, hACE2-293T-293T, Vero, and LLC-MK2) and 14 cell lines overexpressing ACE2 from different species. Mutant strains did not show increased infectivity or cross-species transmission. Neutralization activity against these pseudoviruses was evaluated using mouse serum and 11 monoclonal antibodies. The neutralizing activity of immunized mouse serum was not significantly reduced with the mutant strains, but the mutant strains from Portugal could evade nine of the 11 monoclonal antibodies tested. Neutralization resistance was mainly caused by the mutations S477N, N439K, and N501Y in the spike-receptor binding domain. These findings emphasize the importance of SARS-CoV-2 mutation tracking in different regions for epidemic prevention and control.

Rapid visual detection of porcine reproductive and respiratory syndrome virus via recombinase polymerase amplification combined with a lateral flow dipstick - Xiao-Xiao Tian; Tao Wang; Xing-Yang Cui; Xin-Yi Huang; Yue Sun; Da-Song Xia; Yong-Bo Yang; Xue-Hui Cai; Tong-Qing An (Archives of Virology, 2022)

Tropical tall forests are more sensitive and vulnerable to drought than short forests - Liyang Liu; Xiuzhi Chen; Philippe Ciais; Wenping Yuan; Fabienne Maignan; Jin Wu; Shilong Piao; Ying‐Ping Wang; Jean‐Pierre Wigneron; Lei Fan; Pierre Gentine; Xueqin Yang; et al. (Global Change Biology, 2022)
Our limited understanding of the impacts of drought on tropical forests significantly impedes our ability in accurately predicting the impacts of climate change on this biome. Here, we investigated the impact of drought on the dynamics of forest canopies with different heights using time‐series records of remotely sensed Ku‐band vegetation optical depth (Ku‐VOD), a proxy of top‐canopy foliar mass and water content, and separated the signal of Ku‐VOD changes into drought‐induced reductions and subsequent non‐drought gains. Both drought‐induced reductions and non‐drought increases in Ku‐VOD varied significantly with canopy height. Taller tropical forests experienced greater relative Ku‐VOD reductions during drought and larger non‐drought increases than shorter forests, but the net effect of drought was more negative in the taller forests. Meta‐analysis of in situ hydraulic traits supports the hypothesis that taller tropical forests are more vulnerable to drought stress due to smaller xylem‐transport safety margins. Additionally, Ku‐VOD of taller forests showed larger reductions due to increased atmospheric dryness, as assessed by vapor pressure deficit, and showed larger gains in response to enhanced water supply than shorter forests. Including the height‐dependent variation of hydraulic transport in ecosystem models will improve the simulated response of tropical forests to drought.

Oxidation of organoarsenicals and antimonite by a novel flavin monooxygenase widely present in soil bacteria - Jun Zhang; Jian Chen; Yi‐Fei Wu; Zi‐Ping Wang; Ji‐Guo Qiu; Xiao‐Long Li; Feng Cai; Ke‐Qing Xiao; Xiao‐Xu Sun; Barry P. Rosen; Fang‐Jie Zhao (Environmental Microbiology, 2022)
Summary Arsenic can be biomethylated to form a variety of organic arsenicals differing in toxicity and environmental mobility. Trivalent methylarsenite (MAs(III)) produced in the methylation process is more toxic than inorganic arsenite (As(III)). MAs(III) also serves as a primitive antibiotic and, consequently, some environmental microorganisms have evolved mechanisms to detoxify MAs(III). However, the mechanisms of MAs(III) detoxification are not well understood. In this study, we identified an arsenic resistance ( ars ) operon consisting of three genes, arsRVK , that contribute to MAs(III) resistance in Ensifer adhaerens ST2. ArsV is annotated as an NADPH‐dependent flavin monooxygenase with unknown function. Expression of arsV in the arsenic hypersensitive Escherichia coli strain AW3110 Δars conferred resistance to MAs(III) and the ability to oxidize MAs(III) to MAs(V). In the presence of NADPH and either FAD or FMN, purified ArsV protein was able to oxidize both MAs(III) to MAs(V) and Sb(III) to Sb(V). Genes with arsV ‐like sequences are widely present in soils and environmental bacteria. Metagenomic analysis of five paddy soils showed the abundance of arsV ‐like sequences of 0.12–0.25 ppm. These results demonstrate that ArsV is a novel enzyme for the detoxification of MAs(III) and Sb(III) and the genes encoding ArsV are widely present in soil bacteria.

Changing legislative thinking in China to better protect wild animals and human health - Guirong Fang; Hong Liu; Ka Wu; Tongqing Wei; Qing Wang (Conservation Biology, 2022)
The COVID‐19 pandemic has exposed the inadequacy of China's legal protection of wildlife. Long‐standing illegal wildlife trade in China and worldwide increases the risk of zoonotic infectious diseases. We sought to improve the understanding of China’ legal system for the protection of wildlife, which has at its core the wildlife protection law, by systematically evaluating the laws and regulations of China's Wildlife Protection Framework. We examined how existing legal documents (e.g., the Wildlife Protection Law 2018) are directly or indirectly related to wildlife conservation. The inherent defects of wildlife protection legislation include a narrow scope of protection, insufficient public participation, and inconsistent enforcement among responsible agencies. Solutions to improve China's Wildlife Protection Law include expanding the legal protection of wildlife, and improving monitoring of wildlife protection. Strengthening legislation will be the basis for effective regulation of the use of wild animals. We advocate the establishment of a sound wildlife protection legal system for resolving conflicts between humans and wild animals and preventing zoonotic disease, such a system will have a profound impact on the sustainable development of China's wildlife resources.

Passive Sonar Target Tracking Based on Deep Learning - Ying Wang; Hongjian Wang; Qing Li; Yao Xiao; Xicheng Ban (Journal of Marine Science and Engineering, 2022)
At present, the tracking accuracy of underwater passive target tracking is often limited due to models that are overly simple, with low complexity, poor universality, and an inability to learn. In this paper, a cubature Kalman filter (CKF) algorithm based on a gated recurrent unit (GRU) network is proposed. The filter innovation, prediction error, and filter gain obtained from the CKF are used as the input to the GRU network, and the filter error value is used as the output to train the network. End-to-end online learning is carried out using the designed fully connected network, and the current state of the target is predicted. In this paper, a deep neural network based on the GRU architecture is used to convert the tracking prediction problem into a time series prediction problem in the field of artificial intelligence, and its strong fitting ability is used to resolve the uncertainty of the target motion. Simulation results show that an unmanned underwater vehicle (UUV) state estimation method based on the GRU filter proposed in this paper offers better accuracy and stability than the traditional state estimation method.

Best Practice Data Standards for Discrete Chemical Oceanographic Observations - Li-Qing Jiang; Denis Pierrot; Rik Wanninkhof; Richard A. Feely; Bronte Tilbrook; Simone Alin; Leticia Barbero; Robert H. Byrne; Brendan R. Carter; Andrew G. Dickson; Jean-Pierre Gattuso; Dana Greeley; et al. (Frontiers in Marine Science, 2022)
Effective data management plays a key role in oceanographic research as cruise-based data, collected from different laboratories and expeditions, are commonly compiled to investigate regional to global oceanographic processes. Here we describe new and updated best practice data standards for discrete chemical oceanographic observations, specifically those dealing with column header abbreviations, quality control flags, missing value indicators, and standardized calculation of certain properties. These data standards have been developed with the goals of improving the current practices of the scientific community and promoting their international usage. These guidelines are intended to standardize data files for data sharing and submission into permanent archives. They will facilitate future quality control and synthesis efforts and lead to better data interpretation. In turn, this will promote research in ocean biogeochemistry, such as studies of carbon cycling and ocean acidification, on regional to global scales. These best practice standards are not mandatory. Agencies, institutes, universities, or research vessels can continue using different data standards if it is important for them to maintain historical consistency. However, it is hoped that they will be adopted as widely as possible to facilitate consistency and to achieve the goals stated above.

A CNN-based rescaling algorithm and performance analysis for spatial resolution enhancement of Landsat images - Qing Wang; Heidi R. Howard; Juliana M. Mcmillan; Guangxing Wang; Xiaoyu Xu (International Journal of Remote Sensing, 2022)

Chemical constituents of Sophora flavescens Ait. and cytotoxic activities of two new compounds - Guo-Qing Long; Dong-Dong Wang; Jing Wang; Jing-Ming Jia; An-Hua Wang (Natural Product Research, 2022)

Responses of suction buckets subjected to sustained vertical uplift loads in sand - Xingxing Wang; Qing Yang; Xiaowei Tang (Marine Georesources & Geotechnology, 2022)

Investigation of the risk of valproic acid–induced tremor: clinical, neuroimaging, and genetic factors - Lili Lan; Xu Zhao; Si Jian; Cun Li; Man Wang; Qing Zhou; Shanshan Huang; Suiqiang Zhu; Huicong Kang; Heidi E. Kirsch (Psychopharmacology, 2022)

MAPK5 and MAPK10 overexpression influences strawberry fruit ripening, antioxidant capacity and resistance to Botrytis cinerea - Yunting Zhang; Yu Long; Yiting Liu; Min Yang; Liangxin Wang; Xiaoyang Liu; Yong Zhang; Qing Chen; Mengyao Li; Yuanxiu Lin; Haoru Tang; Ya Luo (Planta, 2022)

Cloning and functional analysis of soluble acid invertase 2 gene (SbSAI-2) in sorghum - Wuyuntanmanda; Fen-Xia Han; Bao-Qing Dun; Ji Zhang; Zhi Wang; Yi Sui; Li Zhu; Gui-Ying Li (Planta, 2022)

Association of Increased Amygdala Activity with Stress-Induced Anxiety but not Social Avoidance Behavior in Mice - Shou-He Huang; Wei-Zhu Liu; Xia Qin; Chen-Yi Guo; Qing-Cheng Xiong; Yu Wang; Ping Hu; Bing-Xing Pan; Wen-Hua Zhang (Neuroscience Bulletin, 2022)

Mdivi-1 Modulates Macrophage/Microglial Polarization in Mice with EAE via the Inhibition of the TLR2/4-GSK3β-NF-κB Inflammatory Signaling Axis - Xiaoqin Liu; Xiaojuan Zhang; Xiaojie Niu; Peijun Zhang; Qing Wang; Xiuhua Xue; Guobin Song; Jiezhong Yu; Guoping Xi; Lijuan Song; Yanhua Li; Cungen Ma (Molecular Neurobiology, 2022)

Nitric Oxide Signaling Pathway in Ventral Tegmental Area is Involved in Regulation of 7,8-Dihydroxyflavone on Alcohol Consumption in Rats - Qing Gao; Tao Yang; Xin-Xin Li; Jun-Wei Xiong; Wei Ma; Yan-Min Xu; Yong Liu; Hong-Yan Zhang; Qi-Yu Wang; Hong-Xuan Wang; Ying Peng; Xiao-Feng Zhu; et al. (Molecular Neurobiology, 2022)

Caffeine Inhibits Activation of the NLRP3 Inflammasome via Autophagy to Attenuate Microglia-Mediated Neuroinflammation in Experimental Autoimmune Encephalomyelitis - Hui-Qi Wang; Kai-Yi Song; Jin-Zhou Feng; Si-Yuan Huang; Xiu-Ming Guo; Lei Zhang; Gang Zhang; Ying-Chao Huo; Rong-Rong Zhang; Yue Ma; Qing-Zhe Hu; Xin-Yue Qin (Journal of Molecular Neuroscience, 2022)

Retraction Note to: Revisiting the male genetic landscape of China: a multi-center study of almost 38,000 Y-STR haplotypes - Michael Nothnagel; Guangyao Fan; Fei Guo; Yongfeng He; Yiping Hou; Shengping Hu; Jiang Huang; Xianhua Jiang; Wook Kim; Kicheol Kim; Chengtao Li; Hui Li; et al. (Human Genetics, 2022)

Effects of B-azolemiteacrylic on life-history traits and demographic parameters of two-spotted spider mite, Tetranychus urticae (Acari: Tetranychidae) - Suqin Shang; Yun Chang; Wei-Zhen Li; Wang Chang-Qing; Nie Peng-Cheng (Experimental and Applied Acarology, 2022)
The present study was conducted to evaluate sublethal effects of B-azolemiteacrylic on the two-spotted spider mite, Tetranychus urticae Koch (Acari: Tetranychidae). Female adults of T. urticae were exposed to LC 10 and LC 30 of the acaricide, and the effects on treated females and their offspring were evaluated. The results showed that the fecundity of F 0 female adults treated with LC 10 and LC 30 of B-azolemiteacrylic was reduced by 30.9 and 39.2%, respectively. Longevity and oviposition period of the females were significantly reduced as well. The developmental duration of egg and deutonymph stage of the F 1 generation were not significantly different from that of the control. The protonymph stage after LC 30 treatment lasted significantly longer, whereas the larva, deutonymph and female stage were significantly shorter than the control. The oviposition period of the F 1 generation was significantly shortened, the fecundity of each female decreased significantly, and the ratio of female-to-male was reduced too. Moreover, the average generation period of T. urticae after LC 10 and LC 30 treatments was shorter than that of the control, and the net production rate ( R 0 ), intrinsic rate of increase ( r m ) and finite rate of increase ( λ ) were all reduced by 33.3, 7.5 and 1.9% (LC 10 treatment) and by 51.3, 14.8 and 3.6% (LC 30 treatment), respectively. The population doubling time was prolonged by 7.5 and 14.8% after LC 10 and LC 30 treatments, respectively, compared with the control. These results indicate that B-azolemiteacrylic may effectively inhibit the development rate of the F 0 and F 1 populations of T. urticae , which will help design integrated strategies for the comprehensive control of T. urticae and rational use of pesticides in the field.

Sporosarcina beigongshangi sp. nov., isolated from pit mud of Baijiu - Zhanbin Sun; Liyin Guo; Yi Yan; Xiaoping Zhang; Jiaxuan Wang; Bo Liu; Jialiang Xu; Qing Ren (Archives of Microbiology, 2022)

Deinococcus aestuarii sp. nov. and Deinococcus aquaedulcis sp. nov., two novel resistant bacteria isolated from pearl river estuary - Ling-Zi Yin; Jia-Ling Li; Ze-Tao Liu; Bao-Zhu Fang; Pandeng Wang; Xiao-Qing Luo; Lei Dong; Li Duan; Shan-Hui Li; Wen-Jun Li (Antonie van Leeuwenhoek, 2022)

Design of a Long-Acting Rivastigmine Transdermal Delivery System: Based on Computational Simulation - Xue Han; Jingchuan Liu; Xiaoyue Hu; Wei Wang; Qing Wang (AAPS PharmSciTech, 2022)

Synthesis and biological evaluation of camptothecin substituted norcantharimide derivatives - Qing Lan; Yiqi Zhou; Xianheng Wang; Yuhe Wang; Changkuo Zhao (Natural Product Research, 2021)

Isocitrate dehydrogenase of Bacillus cereus is involved in biofilm formation - Linlin Zhao; Qing Liu; Qiubin Huang; Fengying Liu; Huiping Liu; Gang Wang (World Journal of Microbiology and Biotechnology, 2021)

Ifenprodil Improves Long-Term Neurologic Deficits Through Antagonizing Glutamate-Induced Excitotoxicity After Experimental Subarachnoid Hemorrhage - Jing-yi Sun; Shi-jun Zhao; Hong-bin Wang; Ya-jun Hou; Qiong-jie Mi; Ming-feng Yang; Hui Yuan; Qing-bin Ni; Bao-liang Sun; Zong-yong Zhang (Translational Stroke Research, 2021)

Intra-Articular Injection of miR-29a-3p of BMSCs Promotes Cartilage Self-Repairing and Alleviates Pain in the Rat Osteoarthritis - Qing Wang; Yong Chen; Xiaofeng Shen; Ji Chen; Yuwei Li (Tissue Engineering and Regenerative Medicine, 2021)

Recent advances in tissue stem cells - Xin Fu; Qiang He; Yu Tao; Mengdi Wang; Wei Wang; Yalong Wang; Qing Cissy Yu; Fang Zhang; Xiaoyu Zhang; Ye-Guang Chen; Dong Gao; Ping Hu; et al. (Science China Life Sciences, 2021)

Mechanical Properties of Limestone After High-Temperature Treatment Under Triaxial Cyclic Loading and Unloading Conditions - Qing-bin Meng; Jiang-Feng Liu; Hai Pu; Li-yuan Yu; Jiang-yu Wu; Cong-kai Wang (Rock Mechanics and Rock Engineering, 2021)

Recombinant Avian β-Defensin Produced by Food-Grade Lactococcus as a Novel and Potent Immunological Enhancer Adjuvant for Avian Vaccine - Tingting Wang; Zhihao Wang; Jielan Mi; Wenqian Wang; Kai Li; Xiaole Qi; Yulong Gao; Li Gao; Changjun Liu; Yanping Zhang; Qing Pan; Xiaomei Wang; et al. (Probiotics and Antimicrobial Proteins, 2021)
In this study, we expressed rAvBD1-2–6-13 protein through Lactococcus lactis NZ3900, and the effects of the recombinant L. lactis NZ3900 as an immune enhancer and immune adjuvant were verified using in vivo and in vitro tests. In vitro tests revealed that recombinant L. lactis NZ3900 significantly activated the NF-κB signaling pathway and IRF signaling pathway in J774-Dual™ report cells and significantly increased the transcript levels of IL-10, IL-12p70, CD80, and CD86 in chicken PBMCs and chicken HD11 cells. In vivo experiments revealed that the immunized group supplemented with recombinant L. lactis NZ3900 as an adjuvant had significantly higher serum antibody titers and higher proliferative activity of PBMCs in the blood of the chickens immunized with NDV live and inactivated vaccines. Our study shows that the recombinant L. lactis NZ3900 has strong immunomodulatory activity both in vivo and in vitro and is a potential immune enhancer. Our work lays the foundation for the research and development of new animal immune enhancers for application in the poultry industry.

Identification S100A9 as a potential biomarker in neuroblastoma - Xian Chen; Yukun Xue; Jiao Feng; Qingwu Tian; Yunyuan Zhang; Qing Wang (Molecular Biology Reports, 2021)
Background More than half of Neuroblastoma (NB) patients presented with distant metastases and the relapse of metastatic patients was up to 90%. It is urgent to explore a biomarker that could facilitate the prediction of metastasis in NB patients. Methods and results In the present study, we systematically analyzed Gene Expression Omnibus datasets and focused on identifying the critical molecular networks and novel key hub genes implicated in NB metastasis. In total, 176 up-regulated and 19 down-regulated differentially expressed genes (DEGs) were identified. Based on these DEGs, a PPI network composed of 150 nodes and 452 interactions was established. Through PPI network identification combined with qRT-PCR, ELISA and IHC, S100A9 was screened as an outstanding gene. Furthermore, in vitro tumorigenesis assays demonstrated that S100A9 overexpression enhanced the proliferation, migration and invasion of NB cells. Conclusions Taken together, our findings suggested that S100A9 could participate in NB tumorigenesis and progression. In addition, S100A9 has the potential to be used as a promising clinical biomarker in the prediction of NB metastasis.

Synthesis and evaluation of mycophenolic acid derivatives as potential anti-Toxoplasma gondii agents - Fan-Fan Shang; Mei-Yuan Wang; Jiang-Ping Ai; Qing-Kun Shen; Hong-Yan Guo; Chun-Mei Jin; Fen-Er Chen; Zhe-Shan Quan; Lili Jin; Changhao Zhang (Medicinal Chemistry Research, 2021)

Involvement of the nociceptin opioid peptide receptor in morphine-induced antinociception, tolerance and physical dependence in female mice - Xiao-Qing Hao; Zhi-Yuan Wang; Jian-Min Chen; Ning Wu; Jin Li (Metabolic Brain Disease, 2021)

A novel ceruloplasmin mutation identified in a Chinese patient and clinical spectrum of aceruloplasminemia patients - Wan-Qing Xu; Wang Ni; Rou-Min Wang; Yi Dong; Zhi-Ying Wu (Metabolic Brain Disease, 2021)

SDF-1 secreted by mesenchymal stem cells promotes the migration of endothelial progenitor cells via CXCR4/PI3K/AKT pathway - Xiaoyi Wang; Huijiao Jiang; Lijiao Guo; Sibo Wang; Wenzhe Cheng; Longfei Wan; Zhongzhou Zhang; Lihang Xing; Qing Zhou; Xiongfeng Yang; Huanhuan Han; Xueling Chen; et al. (Journal of Molecular Histology, 2021)

Colorado geoid computation experiment: overview and summary - Yan Ming Wang; Laura Sánchez; Jonas Ågren; Jianliang Huang; René Forsberg; Hussein A. Abd-Elmotaal; Kevin Ahlgren; Riccardo Barzaghi; Tomislav Bašić; Daniela Carrion; Sten Claessens; Bihter Erol; et al. (Journal of Geodesy, 2021)

Effects of Herbaspirillum sp. p5-19 assisted with alien soil improvement on the phytoremediation of copper tailings by Vetiveria zizanioides L. - Qing Fang; Tao Huang; Ning Wang; Ziwei Ding; Qingye Sun (Environmental Science and Pollution Research, 2021)

Spatio-temporal evolution and influencing factors of land use in Tibetan region: 1995–2025 - Li chen; Qing wang (Earth Science Informatics, 2021)

Analysis of the starch properties in tetraploid wheat–Aegilops sharonensis amphidiploid - Qing Li; Xuteng Zhang; Na Lin; Guzmán Carlos; Jingyu Lan; Huaping Tang; Pengfei Qi; Jian Ma; Jirui Wang; Guoyue Chen; Wei Li; Zhien Pu; et al. (Cereal Research Communications, 2021)

Biological Removal of Se and Cd from Acidic Selenite- and Cadmium-containing Wastewater with Limited Carbon Availability - Taotao Zeng; Qing Hu; Xiaoling Zhang; Haidu Nong; Aijie Wang (Bulletin of Environmental Contamination and Toxicology, 2021)

High-Resolution Geochemical Records in the Inner Shelf Mud Wedge of the East China Sea and Their Indication to the Holocene Monsoon Climatic Changes and Events - Longsheng Wang; Bin Zhou; Bang Zheng; Ke Wang; Xi Mei; Qing Wang; Xiaohui Wang; Hongbo Zheng (Journal of Ocean University of China, 2021)

Correction to: Microphysics and Optical Attenuation in Fog: Observations from Two Coastal Sites - Qing Wang; Ryan T. Yamaguchi; John A. Kalogiros; Zachary Daniels; Denny P. Alappattu; Haflidi Jonsson; Oswaldo Alvarenga; Alex Olson; Benjamin J. Wauer; David G. Ortiz-Suslow; Harindra Joseph Fernando (Boundary-Layer Meteorology, 2021)

Microphysics and Optical Attenuation in Fog: Observations from Two Coastal Sites - Qing Wang; Ryan T. Yamaguchi; John A. Kalogiros; Zachary Daniels; Denny P. Alappattu; Haflidi Jonsson; Oswaldo Alvarenga; Alex Olson; Benjamin J. Wauer; David G. Ortiz-Suslow; Harindra Joseph Fernando (Boundary-Layer Meteorology, 2021)
A total of 15 fog events from two field campaigns are investigated: the High Energy Laser in Fog (HELFOG) project (central California) and the Toward Improving Coastal Fog Prediction (C-FOG) project (Ferryland Newfoundland). Nearly identical sensors were used in both projects to sample fog droplet-size spectra, wind, turbulence, and thermodynamic properties near the surface. Concurrent measurements of visibility were made by the present weather detector in both experiments, with the addition of a two-ended transmissometer in the HELFOG campaign. The analyses focused first on contrasting the observed fog microphysics and the associated thermodynamics from fog events in the two locations. The optical attenuation by fog was investigated using three methods: (1) derived from Mie theory using the measured droplet-size distribution, (2) parametrized as a function of fog liquid water content, and (3) parametrized in terms of total fog droplet number concentration. The consistency of these methods was investigated. The HELFOG data result in an empirical relationship between the meteorological range and liquid water content. Validation of such relationship is problematic using the C-FOG data due to the presence of rain and other factors. The parametrization with droplet number concentration only does not provide a robust visibility calculation since it cannot represent the effects of droplet size on visibility. Finally, a preliminary analysis of the mixed fog/rain case is presented to illustrate the nature of the problem to promote future research.

Large-Scale Synoptic Systems and Fog During the C-FOG Field Experiment - Clive E. Dorman; Sebastian W. Hoch; Ismail Gultepe; Qing Wang; Ryan T. Yamaguchi; H. J. S. Fernando; Raghavendra Krishnamurthy (Boundary-Layer Meteorology, 2021)
The goal of this work is to summarize synoptic meteorological conditions during the Coastal Fog (C-FOG) field project that took place onshore and offshore of the Avalon Peninsula, Newfoundland, from 25 August until 8 October 2018. Visibility was measured at three locations at the Ferryland supersite that are about 1 km from each other, and at two additional sites 66 and 76 km to the north. Supporting meteorological measurements included surface winds, air temperature, humidity, pressure, radiation, cloud-base height, and atmospheric thermodynamic profiles from radiosonde soundings. Statistics are presented for surface measurements during fog events including turbulence kinetic energy, net longwave radiation, visibility, and precipitation. Eleven fog events are observed at Ferryland. Each significant fog event is related to a large-scale cyclonic system. The longest fog event is due to interaction of a northern deep low and a tropical cyclone. Fog occurrence is also examined across Atlantic Canada by including Sable Island, Yarmouth, Halifax, and Sydney. It is concluded that at Ferryland, all significant fog events occur under a cyclonic system while at Sable Island all significant fog events occur under both cyclonic and anticyclonic systems. The fog-formation mechanism involves cloud lowering and stratus broadening or only stratus broadening for the cyclonic systems while for the anticyclonic systems it is stratus broadening or radiation. Although widely cited as the main cause of fog in Atlantic Canada, advection fog is not found to be the primary or sole fog type in the events examined.

Hyphomicrobium album sp. nov., isolated from mountain soil and emended description of genus Hyphomicrobium - Qing Xu; Yuxiao Zhang; Xing Wang; Gejiao Wang (Archives of Microbiology, 2021)

Effects of specimen preparation method and strain rate on the mechanical responses of a clayey loess - Dian-Qing Li; Jinyuan Wang; Rui Rui (Arabian Journal of Geosciences, 2021)

A novel BRET based genetic coded biosensor for apoptosis detection at deep tissue level in live animal - Yueling Zhang; Juan Hu; Meijuan Yu; Zhirong Wang; Hucheng Qing; Huheng Fu; Liudi Yuan; Fei Li; Sheng Zhao (Apoptosis, 2021)

PM2.5 Elements in the Rural Area of Jing-Jin-Ji Region in China: Source Identification and Health Risk Assessment - Yao Qu; Xiao-Qing Liu; Hui-Kun Liu; Qi-Yuan Wang; Chong-Shu Zhu; Yue Zhou; Ren-Jian Zhang; Jun-Ji Cao (Aerosol Science and Engineering, 2021)

Applying the Tilt-depth and Tilt-Euler techniques of gravity data to decipher the basement depth in Sichuan Basin, China - Qing Chen; Yunpeng Dong; Xianfeng Tan; Jiabei Wang; Xiaoyu Huang; Hao Chen (Acta Geophysica, 2021)

Ecological studies of colonized invertebrate communities on cultivated seaweeds in a typical mariculture zone, China - Qing Wang; Hui Ren; Yufeng Yang (Marine Ecology, 2021)
The invertebrate communities on floating cultivated seaweeds were studied by both field surveys and experiments in order to analyze community structure in a typical mariculture zone, Nanao, South China. Samples of invertebrates were collected from the water and the thalli of the seaweeds, Gracilaria lemaneiformis and G. chouae . The results showed that both species were rapidly colonized by invertebrates after being introduced into the mariculture region. The communities on the seaweeds were significantly different from those in the ambient waters. Invertebrate abundance was much higher in the seaweed than in the water. The high proportion of larvae indicates that these species are using the seaweed thalli as a platform for reproduction. Therefore, large‐scale seaweed cultivation is beneficial for colonization of invertebrates and shelters higher numbers of copepod larvae than in the sea. This drives ecological changes in the invertebrate communities in coastal ecosystems and facilitates interactions with other communities and higher trophic levels in the cultivated seaweed food web. We propose a conceptual model that summarizes the results from this study and guides future studies on the relationships between seaweed and the invertebrate community.

Molecular identification and phylogenetic analysis of fungal pathogens isolated from diseased fish in Xinjiang, China - Yan‐Zhen Zhang; Qing‐Dian Han; Long‐Wei Fu; Yong‐Xing Wang; Zhi‐Hai Sui; Yun‐Guo Liu (Journal of Fish Biology, 2021)
The outbreaks of fungal diseases in cultured fish have been severe in recent years, which is harmful to the healthy and sustainable development of fish farming. In this study, an investigation was conducted for significant fungal infections of 12 species of fish in four regions in Xinjiang, China, to understand the distribution of local fish fungal pathogens. Twenty‐six fungal strains with pathogenicity were isolated, and the challenge experiment showed that eight strains from Changji area had high infection rate to fish eggs. Based on internal transcribed spacer sequence data and molecular analysis, the 26 strains were classified into nine different species of six fungal genera. Phylogenetic analysis showed that all strains were divided into two clades, namely Cluster 1 (contains only the genus Mucor ) and Cluster 2 (consists of five small branches), and the distribution of strains from the same region was scattered in two clusters. There is no strict host selectivity for these fungi to infect fish. Mucor sp. are the main fungal pathogen of fish in these four regions, whereas Hypophthalmichthys molitrix and Carassius auratus are two types of fish that were susceptible to pathogen. In addition, the environmental adaptability experiments showed that eight highly pathogenic strains have different adaptability to the environment, and their optimum temperature and pH were 25°C and 7.0, respectively, whereas the concentration of NaCl was negatively correlated with the growth of strains. Therefore, these results indicated that the coinfection of multiple fungal pathogens in a culture region should be considered in the future study.

Environmental contamination with SARS‐CoV ‐2 in COVID ‐19 hospitals in Wuhan, China, 2020 - Wei Liu; Dingchen Li; Chaojie Yang; Fangyan Chen; Ruizhong Jia; Leili Jia; Xinyi Xia; Shanhong Fan; Qing Tan; Yuehua Ke; Yong Chen; Haifeng Li; et al. (Environmental Microbiology, 2021)
Summary Coronavirus disease 2019 (COVID‐19) pandemic has caused high number of infections and deaths of healthcare workers globally. Distribution and possible transmission route of SARS‐CoV‐2 in hospital environment should be clarified. We herein collected 431 environmental (391 surface and 40 air) samples in the intensive care unit (ICU) and general wards (GWs) of three hospitals in Wuhan, China from February 21 to March 4, 2020, and detected SARS‐CoV‐2 RNA by real‐time quantitative PCR. The viral positive rate in the contaminated areas was 17.8% (28/157), whereas there was no virus detected in the clean areas. Higher positive rate (22/59, 37.3%) was found in ICU than that in GWs (3/63, 4.8%). The surfaces of computer keyboards and mouse in the ICU were the most contaminated (8/10, 80.0%), followed by the ground (6/9, 66.7%) and outer glove (2/5, 40.0%). From 17 air samples in the contaminated areas, only one sample collected at a distance of around 30 cm from the patient was positive. Enhanced surface disinfection and hand hygiene effectively decontaminated the virus from the environment. This finding might help understand the transmission route and contamination risk of SARS‐CoV‐2 and evaluate the effectiveness of infection prevention and control measures in healthcare facilities.

Two new diterpenoids with their antiproliferative activities from the supercritical fluid extraction of Croton crassifolius root - Chao Liu; Rui-rui Zhang; Qing-lin Niu; Jing Zhang; Mu-xuan Wang; Na-na Meng; Qing Wang; Jin-yue Sun; Wen-liang Wang (Natural Product Research, 2021)

GALNT14 promotes cancer stem cell-like characteristics and metastasis of nasopharyngeal carcinoma cells through upregulating SOX4 - Yali Wang; Qing Gan; Xiao Cai; Zejun Chen; Qianqian Liu; Yundan Bai (Molecular & Cellular Toxicology, 2021)

One new α , β -unsaturated 7-ketone sterol from the mangrove-derived fungus Phomopsis sp.MGF222 - Xiao-Chen Zhu; Guo-Lei Huang; Rong-Qing Mei; Bin Wang; Xue-Ping Sun; You-Ping Luo; Jing Xu; Cai-Juan Zheng (Natural Product Research, 2021)

A new phenol derivative isolated from mangrove-derived fungus Eupenicillium sp. HJ002 - Rong-Qing Mei; Xu-Hua Nong; Bin Wang; Xue-Ping Sun; Guo-Lei Huang; You-Ping Luo; Cai-Juan Zheng; Guang-Ying Chen (Natural Product Research, 2021)

A New Instrumental Array in Sichuan, China, to Monitor Vibrations and Perturbations of the Lithosphere, Atmosphere, and Ionosphere - Chieh-Hung Chen; Yang-Yi Sun; Kai Lin; Chen Zhou; Rui Xu; Haiyin Qing; Yongxin Gao; Tao Chen; Fei Wang; Huaizhong Yu; Peng Han; Chi-Chia Tang; et al. (Surveys in Geophysics, 2021)

MicroRNA-31-3p/RhoA signaling in the dorsal hippocampus modulates methamphetamine-induced conditioned place preference in mice - Hongyan Qian; Qing Shang; Min Liang; Baoyao Gao; Jing Xiao; Jing Wang; Axiang Li; Canyu Yang; Jianmin Yin; Gang Chen; Tao Li; Xinshe Liu (Psychopharmacology, 2021)

The Utility of Gordon’s Standard NIR Empirical Atmospheric Correction Algorithm for Unmanned Aerial Vehicle Imagery - Liang Ma; Yan Liu; Xiang Yu; Chao Zhan; Bowen Zhang; Lingxing Lu; Zihui Liu; Bing Li; Guangshun Sun; Qing Wang (Journal of the Indian Society of Remote Sensing, 2021)

MamZ protein plays an essential role in magnetosome maturation process of Magnetospirillum gryphiswaldense MSR-1 - Sha Wu; Qing Wang; Xu Wang; Ruixue Guo; Tongwei Zhang; Yongxin Pan; Feng Li; Ying Li (Journal of Oceanology and Limnology, 2021)

Association between ambient air pollution and multiple sclerosis: a systemic review and meta-analysis - Chao Tang; Qing-Ru Li; Yan-Mei Mao; Yuan-Rui Xia; Heng-Sheng Guo; Jun-Ping Wang; Zong-Wen Shuai; Dong-Qing Ye (Environmental Science and Pollution Research, 2021)

Comparison of the Bulk and Rhizosphere Soil Prokaryotic Communities Between Wild and Reintroduced Manglietiastrum sinicum Plants, a Threatened Species with Extremely Small Populations - Dai-Fa Su; Qing-Qing Shen; Jun-Yu Yang; Zhi-Ying Li; Wei Xiao; Yong-Xia Wang; Zhang-Gui Ding; Xiao-Long Cui (Current Microbiology, 2021)

Wisdom, predicaments, and challenges of a millennium ancient weir—Dujiangyan Project - Xiao-rong Huang; Xing-yu Zhou; Jin-jun You; Qing Yang; Yan-jun Wang; Kai Ma (Journal of Mountain Science, 2021)

Geochemistry of the Lower Cretaceous limestones in the Eastern Tethys Gyabula Formation (Himalaya, southern Tibet): implications for the depositional environment and tectonic setting - Qing Li; Feng Ding; Micha Ruhl; Yongdong Wang; Ying Li; Lei Yang; Kunzhi Xu; Xiangang Xie (Arabian Journal of Geosciences, 2021)

Sediment Coarsening in Tidal Flats and Stable Coastline of the Abandoned Southern Yellow River Sub-Delta in Response to Fluvial Sediment Flux Decrease During the Past Decades - Lin Zeng; Chao Zhan; Qing Wang; Xianbin Liu; Longsheng Wang; Xueyan Li; Xin Wang; Xiang Yu; Jinzhi Zhang; Buli Cui (Frontiers in Marine Science, 2021)
Due to remarkable reduction of sediment supply, the vulnerability of Yellow River deltaic system increased and ecological impacts occurred to some extent. To have a comprehensive and quantitative understanding of the morphological evolution of deltas, surficial sediments of tidal flat along the abandoned southern Yellow River sub-delta and two adjacent coastal units were systematically collected and evaluated by grain-size analysis in the study. The results reveal that surficial sediments of the abandoned southern Yellow River sub-delta have been coarsening significantly since the 1980s, as characterized by a decrease in both the mud content and the clay/mud ratio. In particular, the transition from cohesive to non-cohesive sediment was completed between 2007 and 2013. With a sharp decrease in sediment flux from the Yellow River estuary, the flood currents from the submarine coastal slope carry few fine particles into the tidal zone, whereas the ebb currents with reverse direction remove some fine particles from the tidal flat. This is a major cause of sediment coarsening in the tidal flat. As sediment coarsening, the coastline of the abandoned southern Yellow River sub-delta has remained stable. The significant change in the grain size of the tidal flat surficial sediments may have a profound impact on the future coastal geomorphic evolution.

Experimental and numerical investigation on the influence of PC window beam on the seismic performance of PC shear wall structures - Linlin Xie; Xun Chong; Lanfang Zhang; Xianguo Ye; Qing Jiang; Decai Wang (European Journal of Environmental and Civil Engineering, 2021)

Late Cretaceous adakitic rocks from the western Tibetan Plateau: implications for the subduction of the Neo-Tethys Ocean - Wei Wang; Qing-Guo Zhai; Pei-Yuan Hu; Sun-Lin Chung; Yue Tang; Hai-Tao Wang; Zhi-Cai Zhu; Hao Wu; Zhi-Qiang Huang (International Geology Review, 2021)

The change of hydrological variables and its effects on vegetation in Central Asia - Qing Peng; Ranghui Wang; Yelin Jiang; Cheng Li; Wenhui Guo (Theoretical and Applied Climatology, 2021)
Water is an important factor that affects local ecological environments, especially in drylands. The hydrological cycle and vegetation dynamics in Central Asia (CA) have been severely affected by climate change. In this study, we employed data from Gravity Recovery and Climate Experiment (GRACE), Global Land Data Assimilation System (GLDAS), Global Land Evaporation Amsterdam Model, and Climate Research Unit to analyze the spatiotemporal changes in hydrological factors (terrestrial water storage (TWS), evapotranspiration, precipitation, and groundwater) in CA from 2003 to 2015. Additionally, the spatiotemporal changes in vegetation dynamics and the influence of hydrological variables on vegetation were analyzed. The results showed that the declining rates of precipitation, evapotranspiration, GRACE-TWS change, GLDAS-TWS change and GW change were 0.40 mm/year, 0.11 mm/year, 50.46 mm/year ( p < 0.05), 8.38 mm/year, and 41.18 mm/year ( p < 0.05), respectively. Human activity (e.g., groundwater pumping) was the dominant in determining the GW decline in CA. Precipitation dominated the changes in evapotranspiration, GRACE-TWS and GLDAS-TWS ( p < 0.05). The 2- to 3-month lagging signal has to do with the transportation from the ground surface to groundwater. The change in the normalized difference vegetation index (NDVI) from 2003 to 2015 indicated the slight vegetation degradation in CA. The results highlighted that precipitation, terrestrial water storage, and soil moisture make important contributions to the vegetation dynamics changes in CA. The effect of precipitation on vegetation growth in spring was significant ( p < 0.05), while the soil moisture effect on vegetation in summer and autumn was higher than that of precipitation.

Expanding the scope of genome editing with SpG and SpRY variants in rice - Jun Ren; Xiangbing Meng; Fengyue Hu; Qing Liu; Yuexuan Cao; Huiying Li; Changjie Yan; Jiayang Li; Kejian Wang; Hong Yu; Chun Wang (Science China Life Sciences, 2021)

Genome-wide analysis and characterization of R2R3-MYB family in pigeon pea (Cajanus cajan) and their functional identification in phenylpropanoids biosynthesis - Jie Yang; Su Zhang; Hongquan Li; Litao Wang; Ying Liu; Lili Niu; Qing Yang; Dong Meng; Yujie Fu (Planta, 2021)

Responses of leaf litter decomposability to nitrogen and phosphorus additions are associated with cell wall carbohydrate composition in a subtropical plantation - Xiang-Min Fang; Xiu-Lan Zhang; Ying-Ying Zong; Wen-Qing Li; Jian-Jun Li; Li-Ping Guo; Huimin Wang; Fu-Sheng Chen (Plant and Soil, 2021)

Evaluation of the prognostic ability of serum uric acid for elderly acute coronary syndrome patients with diabetes mellitus: a prospective cohort study - Yang Jiao; Jihang Wang; Xia Yang; Mingzhi Shen; Hao Xue; Jun Guo; Wei Dong; Yundai Chen; Qing Xi; Zhenhong Fu (Journal of Zhejiang University-SCIENCE B, 2021)

Uniconazole, 6-Benzyladenine, and Diethyl Aminoethyl Hexanoate Increase the Yield of Soybean by Improving the Photosynthetic Efficiency and Increasing Grain Filling in Maize–Soybean Relay Strip Intercropping System - Kai Luo; Chen Xie; Jin Wang; Qing Du; Ping Cheng; Tian Wang; Yongcheng Wu; Wenyu Yang; Taiwen Yong (Journal of Plant Growth Regulation, 2021)

Combination of Electroacupuncture and Constraint-Induced Movement Therapy Enhances Functional Recovery After Ischemic Stroke in Rats - Dong Wang; Lijuan Li; Qing Zhang; Zejun Liang; Liyi Huang; Chengqi He; Quan Wei (Journal of Molecular Neuroscience, 2021)

Diversity and arsenic-metabolizing gene clusters of indigenous arsenate-reducing bacteria in high arsenic groundwater of the Hetao Plain, Inner Mongolia - Yanhong Wang; Dazhun Wei; Ping Li; Zhou Jiang; Han Liu; Chun Qing; Helin Wang (Ecotoxicology, 2021)

Plant growth and diversity performance after restoration in Carex schmidtii tussock wetlands, Northeast China - Dongjie Zhang; Jingkuan Sun; Qian Cui; Xueying Jia; Qing Qi; Xuehong Wang; Shouzheng Tong (Community Ecology, 2021)

Inhibition of Maternal c-Src Ameliorates the Male Offspring Hypertension by Suppressing Inflammation and Neurotransmitters in the Paraventricular Nucleus - Qing Su; Xiao-Jing Yu; Qing Yang; Xiao-Min Wang; Wen-Jie Xia; Hong-Bao Li; Kai-Li Liu; Qiu-Yue Yi; Yu-Ming Kang (Cardiovascular Toxicology, 2021)

Pollution Characteristics of Microplastics in Mollusks from the Coastal Area of Yantai, China - Jiajia Liu; Xiaopeng Zhu; Jia Teng; Jianmin Zhao; Chenghua Li; Encui Shan; Chen Zhang; Qing Wang (Bulletin of Environmental Contamination and Toxicology, 2021)

Microplastic Pollution in Nearshore Sediment from the Bohai Sea Coastline - Xiaopeng Zhu; Wen Ran; Jia Teng; Chen Zhang; Wenjing Zhang; Chaowei Hou; Jianmin Zhao; Xutong Qi; Qing Wang (Bulletin of Environmental Contamination and Toxicology, 2021)

Resting-state abnormalities in functional connectivity of the default mode network in autism spectrum disorder: a meta-analysis - Qing Wang; Hua-Yun Li; Yun-Da Li; Ya-Ting Lv; Hui-Bin Ma; An-Feng Xiang; Xi-Ze Jia; Dong-Qiang Liu (Brain Imaging and Behavior, 2021)

Temporal dynamics alterations of spontaneous neuronal activity in anterior cingulate cortex predict suicidal risk in bipolar II patients - Shui Tian; Rongxin Zhu; Mohammad Ridwan Chattun; Huan Wang; Zhilu Chen; Siqi Zhang; Junneng Shao; Xinyi Wang; Zhijian Yao; Qing Lu (Brain Imaging and Behavior, 2021)

Deep profile soil moisture distribution characteristics for different micro-topographies on the semi-arid Loess Plateau, China - Qing-ping Gou; Qing-ke Zhu; Yi-xuan Li; Xiang-lei Tian; Peng-xiang Wang; Yun-ling Xin; Shu-yuan Luo (Journal of Mountain Science, 2021)

Effects of Dietary Protein and Lipid Levels on Growth Performance, Muscle Composition, Immunity Index and Biochemical Index of the Greenfin Horse-Faced Filefish (Thamnaconus septentrionalis) Juvenile - Zhengxin Xu; Pengfei Zhang; Qing Chang; Siqing Chen; Li Bian; Zhida Wang (Journal of Ocean University of China, 2021)

Highly sialylated mucin-type glycopeptide from porcine intestinal mucosa after heparin extraction: O-glycan profiling and immunological activity evaluation - Xin Zhang; Chen Wang; Qing Han; Xuan Chen; Guoyun Li; Guangli Yu (Glycoconjugate Journal, 2021)

Evaluation and Applications of Multi-Instrument Boundary-Layer Thermodynamic Retrievals - Elizabeth N. Smith; Brian R. Greene; Tyler M. Bell; William G. Blumberg; Ryann Wakefield; Dylan Reif; Qing Niu; Qingyu Wang; David D. Turner (Boundary-Layer Meteorology, 2021)

Diversity patterns and drivers of methanotrophic gene distributions in forest soils across a large latitudinal gradient - Yongping Kou; Wenqiang Zhao; Yanjiao Liu; Yanhong Wu; Jiangtao Xiao; Xiaohu Wang; Haijian Bing; Qing Liu (Global Ecology and Biogeography, 2021)
Aim Methane oxidation driven by soil aerobic methanotrophs exhibits the largest methane sink capacity in forest ecosystems and plays important roles in the alleviation of global warming. Many studies have revealed the distribution of methanotrophs in forest ecosystems at field scales; however, the biogeographical patterns of methanotrophic communities and related ecological processes and the drivers shaping methanotrophic communities at a large scale remain poorly understood. Location China’s forests. Time period 2012–2013. Major taxa studied Methanotrophic communities. Methods We evaluated the geographical distributions of soil methanotrophic communities across 26 forests along a 4,000‐km north–south transect in China using a MiSeq high‐throughput sequencing technique. The assembly processes and drivers of the methanotrophic communities were evaluated using the phylogenetic null model approach and structural equation modelling, respectively. Results The results showed that the upland soil cluster α (USCα) and ammonia‐ oxidizing bacteria‐related (AOB‐rel) methanotrophs were the most abundant taxa in forest soils and exhibited contrasting distributions of relative abundance across different climate zones, suggesting that they occupy different environmental niches. The α ‐diversity pattern of the soil methanotrophic community followed a hump‐shaped pattern along a large latitudinal gradient. Statistical analyses suggest that aridity and vegetation productivity [here represented with the normalized difference vegetation index (NDVI)] are major drivers of the α‐diversity of the methanotrophic community, whereas soil pH is the key environmental factor shaping the β‐diversity of the methanotrophic community at a large scale. Additionally, the community assembly of the methanotrophs primarily resulted from deterministic processes, among which heterogeneous selection had a greater contribution in shaping the methanotrophic community than homogeneous selection. Main conclusions Our study provides new insights into the biogeographical distributions, assembly processes and ecological predictors of the methanotrophic community in forest soil at a large scale. These results can be used to improve simulation models for the better prediction of ecosystem functions under predicted global changes.

Can the native faunal communities be restored from removal of invasive plants in coastal ecosystems? A global meta‐analysis - Zhonghua Ning; Cong Chen; Tian Xie; Zhenchang Zhu; Qing Wang; Baoshan Cui; Junhong Bai (Global Change Biology, 2021)
Coastal ecosystems worldwide are being threatened by invasive plants in the context of global changes. However, how invasive plants influence native faunal communities and whether native faunal communities can recover following the invader removals/controls across global coastal ecosystems are still poorly understood. Here, we present the first global meta‐analysis to quantify the impacts of Spartina species invasions on coastal faunal communities and further to evaluate the outcomes of Spartina species removals on faunal community recovery based on 74 independent studies. We found that invasive Spartina species generally decreased the biodiversity (e.g., species richness), but increased coastal faunal abundance (e.g., individual number) and fitness (e.g., biomass), though the effect on abundance was insignificant. The pattern of influence was strongly dependent on habitat types, faunal taxa, trophic levels, and feeding types. Specifically, Spartina species invasion of mudflats caused greater impacts than invasion of vegetated habitats. Insects and birds at higher trophic levels were strongly affected by invasive Spartina , indicating that invasive plant effects can cascade upward along the food chain. Additionally, impacts of Spartina invasions were more obvious on food specialists such as herbivores and carnivores. Furthermore, our analyses revealed that invader removals were overall beneficial for native faunal communities to recover from the displacement caused by Spartina invasions, but this recovery process depended on specific removal measure and time. For example, the long‐term waterlogging had strong negative impacts on faunal recovery, so it should not be encouraged. Our findings suggest that invasive plants could have contrasting effects on functional responses of native faunal communities. Although invasive plant removals could restore native faunal communities, future functional restorations of invaded ecosystems should take the legacy effects of invasive species on native communities into account. These findings provide insightful implications for future scientific controls of invasive species and ecosystem restoration under intensifying global changes.

A new indole alkaloid with HUVEC proliferation activities from Nauclea officinalis - Shi-Ying Mai; Yong-Hui Li; Xu-Guang Zhang; Yi-Ran Wang; Jun-Qing Zhang; An Jia (Natural Product Research, 2021)

MS1 is essential for male fertility by regulating the microsporocyte cell plate expansion in soybean - Xiaolong Fang; Xiaoyuan Sun; Xiangdong Yang; Qing Li; Chunjing Lin; Jie Xu; Wenjun Gong; Yifan Wang; Lu Liu; Limei Zhao; Baohui Liu; Jun Qin; et al. (Science China Life Sciences, 2021)

Effects of plantation types and patterns on rainfall partition in soil in a mid-subtropical region of China - Mingzhen Sui; Beibei Zhang; Qing Xu; Deqiang Gao; Ying Zhang; Silong Wang (Plant and Soil, 2021)

Utilizing MIKC-type MADS-box protein SOC1 for yield potential enhancement in maize - Guo-qing Song; Xue Han; John T. Ryner; Addie Thompson; Kan Wang (Plant Cell Reports, 2021)
Key message Overexpression of Zea mays SOC gene promotes flowering, reduces plant height, and leads to no reduction in grain production per plant, suggesting enhanced yield potential, at least, through increasing planting density. Abstract MIKC-type MADS-box gene SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 ( SOC1 ) is an integrator conserved in the plant flowering pathway. In this study, the maize SOC1 ( ZmSOC1 ) gene was cloned and overexpressed in transgenic maize Hi-II genotype. The T 0 plants were backcrossed with nontransgenic inbred B73 to produce first generation backcross (BC 1 ) seeds. Phenotyping of both transgenic and null segregant (NT) BC 1 plants was conducted in three independent experiments. The BC 1 transgenic plants showed new attributes such as increased vegetative growth, accelerated flowering time, reduced overall plant height, and increased grain weight. Second generation backcross (BC 2 ) plants were evaluated in the field using two planting densities. Compared to BC 2 NT plants, BC 2 transgenic plants, were 12–18% shorter, flowered 5 days earlier, and showed no reduction in grain production per plant and an increase in fat, starch, and simple sugars in the grain. Transcriptome comparison in young leaves of 56-day-old BC 1 plants revealed that the overexpressed ZmSOC1 resulted in 107 differentially expressed genes. The upregulated transcription factor DNA BINDING WITH ONE FINGER 5.4 (DOF5.4) was among the genes responsible for the reduced plant height. Modulating expression of SOC1 opens a new and effective approach to promote flowering and reduce plant height, which may have potential to enhance crop yield and improve grain quality.

Comparison of pramipexole and levodopa/benserazide combination therapy versus levodopa/benserazide monotherapy in the treatment of Parkinson’s disease: a systematic review and meta-analysis - De-Qi Jiang; Qing-Min Zang; Li-Lin Jiang; Yan Wang; Ming-Xing Li; Jing-Yi Qiao (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

The advances of topology optimization techniques in orthopedic implants: A review - Naichao Wu; Shan Li; Boyan Zhang; Chenyu Wang; Bingpeng Chen; Qing Han; Jincheng Wang (Medical & Biological Engineering & Computing, 2021)

A New AR Method Using BDS Triple-Frequency Observation - Gaochao Yang; Qing Wang; Shiyang Zhou; Bo Zhang; Xin Li (Journal of the Indian Society of Remote Sensing, 2021)

The preference of maize plants for nitrate improves fertilizer N recovery efficiency in an acid soil partially because of alleviated Al toxicity - Jia Lin Wang; Xue Qiang Zhao; Hao Qing Zhang; Ren Fang Shen (Journal of Soils and Sediments, 2021)

Geochemical characteristics and geological implication of ferromanganese crust from CM6 Seamount of the Caroline Ridge in the Western Pacific - Qing Wang; Zhenyan Wang; Kai Liu; Quanchao Cui; Xingyu Shi (Journal of Oceanology and Limnology, 2021)

RETRACTED ARTICLE: Two New Coordination Polymers: Selective Detection of Cu(II) Ion and Treatment Activity on Inner Ear Damage - Jing Liu; Wan-Dong She; Fu-Sen Wang; Qing Zhou (Journal of Fluorescence, 2021)

Transcriptome sequencing of wild soybean revealed gene expression dynamics under low nitrogen stress - Qi Sun; Haoran Lu; Qing Zhang; Di Wang; Jun Chen; Jialei Xiao; Xiaodong Ding; Qiang Li (Journal of Applied Genetics, 2021)

Diffusion tensor imaging indices of acute muscle damage are augmented after exercise in peripheral arterial disease - Jon Stavres; Jianli Wang; Christopher T. Sica; Cheryl Blaha; Michael Herr; Samuel Pai; Aimee Cauffman; Jeffrey Vesek; Qing X. Yang; Lawrence I. Sinoway (European Journal of Applied Physiology, 2021)

Clinical characteristics and serotype distribution of invasive pneumococcal disease in pediatric patients from Beijing, China - Yan Xu; Qing Wang; Kaihu Yao; Fang Dong; Wenqi Song; Gang Liu; Baoping Xu; Wei Shi; Yue Li; Kechun Li; Yingchao Liu; Suyun Qian (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Human Methylmercury Exposure and Potential Impacts in Central Tibet: Food and Traditional Tibetan Medicine - Menghan Cheng; Maodian Liu; Dou Li; Qing Luo; Zhihao Zhang; Liuliang Yuan; Chenghao Yu; Han Xie; Huiming Lin; Qianru Zhang; De Ji; Xuejun Wang (Bulletin of Environmental Contamination and Toxicology, 2021)

Geochemical characteristics and genesis of lower Paleozoic dolomites in the central Bohai Sea - Xiuzhang Song; Zhengxiang Lv; Binchuan Qin; Honghui Wang; Yuanhua Qing; Chunyan Zang; Wei Zhao; Peng Hao; Yinjun He (Arabian Journal of Geosciences, 2021)

2-Arachidonoylglycerol as an Endogenous Cue Negatively Regulates Attachment of the Mussel Perna viridis - Qi Dai; Zhi-Xuan Wang; Yan-Qing Sheng; Zhi-Wen Wu; Yan Qiu; Pei Su; Cai-Huan Ke; Dan-Qing Feng (Frontiers in Marine Science, 2021)
Endocannabinoids play important roles in the functioning of various physiological systems in humans and non-mammalian animals, including invertebrates. However, information concerning their roles in physiological functions in members of the phylum Mollusca is scarce. Here the hypothesis that the endocannabinoids are involved in mediating settlement of marine invertebrates was tested. Two endocannabinoids [N-arachidonoyl ethanolamide (AEA) and 2-arachidonoyl glycerol (2-AG)], and two endocannabinoid-like lipids [N-Oleoylethanolamide (OEA) and N-Palmitoylethanolamide (PEA)] were detected in the green mussel Perna viridis . In particular, 2-AG was present at significantly higher levels in unattached P. viridis compared with attached mussels. The in vivo level of 2-AG was inversely correlated with the attachment activity of P. viridis . Furthermore, exposure to synthetic 2-AG inhibited attachment of P. viridis in a reversible manner. Transcriptomic analysis suggested that up-regulation of 2-AG synthase (Phospholipase C-β, PLC-β) and down-regulation of its degrading enzyme (Monoacylglycerol lipase, MAGL) resulted in higher levels of 2-AG in unattached mussels. A putative mechanism for the negative regulation of mussel attachment by 2-AG is proposed that involves a Ca 2+ - Nitric oxide (NO)- cyclic guanosine monophosphate (cGMP) pathway. This study broadens our understanding of the evolution and roles of the endocannabinoid system in animals, and reveals an endogenous regulatory cue for mussel attachment.

New diterpenoids from the rhizomes of Hedychium forrestii - Wen-Hui Wang; Jie-Jie Gao; Xiao-Fei Zuo; Xu-Jie Qin; Hai-Yang Liu; Qing Zhao (Natural Product Research, 2021)

GPR40 receptor agonist TAK-875 improves cognitive deficits and reduces β-amyloid production in APPswe/PS1dE9 mice - Chao Liu; Zhao-Yan Cheng; Qing-Peng Xia; Yu-Hui Hu; Chen Wang; Ling He (Psychopharmacology, 2021)

Root rot-infected Sanqi ginseng rhizosphere harbors dynamically pathogenic microbiotas driven by the shift of phenolic acids - Baoying Wang; Qing Xia; Yunlong Li; Jun Zhao; Shaozhou Yang; Fugang Wei; Xinqi Huang; Jinbo Zhang; Zucong Cai (Plant and Soil, 2021)

Secondary Packages cannot Protect Liquid Biopharmaceutical Formulations from Dropping-Induced Degradation - Wei-Jie Fang; Jia-Wei Liu; Han Gao; Yan-Chen Qian; Jian-Qing Gao; Haibin Wang (Pharmaceutical Research, 2021)

Recombinant L-HN Fusion Antigen Derived from the L and HN Domains of Botulinum Neurotoxin B Stimulates a Protective Antibody Response Against Active Neurotoxin - Zhen Li; Jian-Sheng Lu; Shan Liu; Rong Wang; Qing Xu; Yun-Zhou Yu; Zhi-Xin Yang (Neurotoxicity Research, 2021)

DJ-1 activates the noncanonical NF-κB pathway via interaction with Cezanne to inhibit the apoptosis and promote the proliferation of Ishikawa cells - Qi-Zhou Zhu; Hao-Yue Liu; Xiao-Yan Zhao; Le-Jia Qiu; Ting-Ting Zhou; Xue-Ying Wang; He-Ping Chen; Zhong-Qing Xiao (Molecular Biology Reports, 2021)

The Protective A673T Mutation of Amyloid Precursor Protein (APP) in Alzheimer’s Disease - Qing Xia; XinYu Yang; JiaBin Shi; ZiJie Liu; YaHui Peng; WenJing Wang; BoWen Li; Yu Zhao; JiaYing Xiao; Lei Huang; DaYong Wang; Xu Gao (Molecular Neurobiology, 2021)

Molecular Characteristics of Thalamic Gliomas in Adults - Tianwei Wang; Xiaodong Niu; Ting Gao; Linmao Zheng; Yongming Qiu; Qing Mao (Journal of Molecular Neuroscience, 2021)

Titanium dioxide nanotubes as drug carriers for infection control and osteogenesis of bone implants - Kun Wang; Haoyu Jin; Qing Song; Jingjing Huo; Jing Zhang; Peng Li (Drug Delivery and Translational Research, 2021)

Gradually evaluating of suicidal risk in depression by semi-supervised cluster analysis on resting-state fMRI - Zhongpeng Dai; Xiangyu Shen; Shui Tian; Rui Yan; Huan Wang; Xinyi Wang; ZhiJian Yao; Qing Lu (Brain Imaging and Behavior, 2021)

Chemotherapy-induced grey matter abnormalities in cancer survivors: a voxel-wise neuroimaging meta-analysis - Running Niu; Mingying Du; Jing Ren; Haomiao Qing; Xiaodong Wang; Guohui Xu; Du Lei; Peng Zhou (Brain Imaging and Behavior, 2021)

OSL chronology of a Palaeolithic site in a humid subtropical mountainous area of southeast China - Jian-hui Jin; Xiao-yang Wang; Zhen-yu Zhou; Yun-ming Huang; Xue-chun Fan; Xin-xin Zuo; Zhi-zhong Li; Zhi-yong Ling; Yong-qing Ren; Shu-tong Li (Journal of Mountain Science, 2021)

Quartz grain surface microtextural evidence for provenance of the Quaternary aggradation red earth deposit, southern China - Qing-bin Fan; Jie Liao; Li Yan; Wei Ye; Tao Wang; Xiao Feng (Journal of Mountain Science, 2021)

Relationship Between Paleogene Reservoir Densification and Hydrocarbon Accumulation in the Xihu Depression - Senqing Hu; Guosheng Xu; Linhai Zhao; Xu Wang; Hengyuan Cui; Wu Zhang; Qing Miao (Journal of Ocean University of China, 2021)

Paleosalinity and Its Association with Organic Matter: A Case Study from the Eocene Shahejie Formation, Laizhou Bay Sag, Bohai Bay Basin (China) - Haoran Liang; Guosheng Xu; Qing Yu; Fanghao Xu; Deying Wang; Zhiyuan Chen (Journal of Ocean University of China, 2021)

Comparison and Calibration of Elemental Measurements in Sediments Using X-Ray Fluorescence Core Scanning with ICP Methods: A Case Study of the South China Sea Deep Basin - Fangjian Xu; Bangqi Hu; Chen Wang; Jingtao Zhao; Feifei Wang; Xue Ding; Qing Li; Jianwei Guo (Journal of Ocean University of China, 2021)

Dynamical and Machine Learning Hybrid Seasonal Prediction of Summer Rainfall in China - Jialin Wang; Jing Yang; Hong-Li Ren; Jinxiao Li; Qing Bao; Miaoni Gao (Journal of Meteorological Research, 2021)

Trade-offs/Synergies in Land-use Function Changes in Central China from 2000 to 2015 - Qing Li; Yong Zhou; Tao Xu; Li Wang; Qian Zuo; Jingyi Liu; Xueping Su; Nan He; Zhengxiang Wu (Chinese Geographical Science, 2021)

Comparisons of several methods for landslide susceptibility mapping: case of the Benzilan and Waka Towns, Southwest China - Jianping Chen; Wei Peng; Xiaohui Sun; Qing Wang; Xudong Han (Arabian Journal of Geosciences, 2021)