Nitric Oxide Enhances Salt Tolerance in Tomato Seedlings by Regulating Endogenous S-nitrosylation Levels - Chunlei Wang; Lijuan Wei; Jing Zhang; Dongliang Hu; Rong Gao; Yayu Liu; Li Feng; Wenting Gong; Weibiao Liao (Journal of Plant Growth Regulation, 2023)

Exposure–response relationship between temperature, relative humidity, and varicella: a multicity study in South China - Yihan Li; Jialing Li; Zhihua Zhu; Weilin Zeng; Qi Zhu; Zuhua Rong; Jianxiong Hu; Xing Li; Guanhao He; Jianguo Zhao; Lihua Yin; Yi Quan; et al. (Environmental Science and Pollution Research, 2023)

Spatiotemporal impacts of climate change and human activities on water resources and ecological sensitivity in the Mekong subregion in Cambodia - Yi Lin; Yu Rong; Lang Li; Fengting Li; Hanchao Zhang; Jie Yu (Environmental Science and Pollution Research, 2023)

Comparative Toxicity of 3–5 Ringed Polycyclic Aromatic Hydrocarbons to Skeletal Development in Zebrafish Embryos and the Possible Reason - Ke Xu; Ying Zhang; Jingyan Zheng; Chonggang Wang; Rong Chen (Bulletin of Environmental Contamination and Toxicology, 2023)

Variations in July extreme precipitation in Henan Province and the related mechanisms - Ma Qianrong; Hu Rui; Wu Yongping; Zhang Jie; Zhi Rong; Feng Guoling (International Journal of Climatology, 2022)
Extreme precipitation in July across Henan Province and the possible mechanisms involved were investigated. The precipitation in Henan reaches its maximum in July. During 1979–2021, the precipitation in July changed weakly, but the intensity (R99p) and frequency (R99f) of extreme precipitation showed certain increasing trends, with a significant increase in northern Henan. The proportion of extreme precipitation in total precipitation exhibited a significant upward trend. Wavelet analysis results showed that the extreme precipitation in Henan mainly has a 2–3‐year periodicity, and remarkable interannual variation. Furthermore, nearly 80% of the July extreme precipitation events within the magnitude of 50–100 mm occurred 2–3 times. The first two empirical orthogonal function modes of July R99p exhibited a quasi‐monopole pattern (EOF1) and meridional dipole pattern (EOF2), respectively. Further analysis revealed that EOF1 and EOF2 were related to the Silk Road teleconnection pattern (SRP) and the East Asia/Pacific teleconnection pattern (EAP). Circulation factors influenced the interannual variation of R99p, especially in recent years. Furthermore, the associated sea surface temperature anomalies over the Western Pacific and Indian Ocean can intensify the eastward extension of the South Asian high and westward strengthening of the western Pacific subtropical high, which further impacted the SRP and EAP pattern and enhanced the increment of extreme precipitation in Henan Province.

The 2014 severe drought over northeast China and its comparison with droughts over the southern regions: A perspective from synergic effects of water vapour and cold air - Dian Yuan; Jiawei Hao; Er Lu; Wei Dai; Rong Gao; Chunyu Zhao; Qiang Zhang; Haiyan Zhao (International Journal of Climatology, 2022)
Northeast China (NEC) is an agricultural base of the country. It suffered a severe drought in 2014. During the drought, the western Pacific subtropical high is stronger than normal and stretches to the west. The warm and moist air in the southwest edge of the high transports northwestwards and thus cannot affect NEC. Over high latitudes, in the regions west and east to NEC, there are large anomalies in geopotential height, which favour meridional exchange and may lead to stronger‐than‐normal cold air intrusions. Because of the lack of warm and moist air supply from the south while the invasion of the cold and dry air from the north, the atmosphere over NEC is finally drier and colder than normal in saturation levels. Based on the physical relation between seasonal precipitation and relative humidity, along with the defined C q and C T , indicators for measuring the changes in moisture and temperature, the effects of water vapour and air temperature on the drought can be linearly separated, and thus compared. Results reveal that, at middle and high levels, the dryness of the air, which plays a positive role in the drought, can offset the negative effect of the coldness, and the atmosphere over NEC then maintains a lower‐than‐normal relative humidity. In the near‐surface level, the air is drier and warmer than normal, which facilitates the drought.

Physiological and transcriptome analysis of Mytilus coruscus in response to Prorocentrum lima and microplastics - Xiao-wen Tang; Rong Yu; Mei-hua Fan; Zhi Yang; Zhi Liao; Zong-xin Yang; Chen-ying Xie; Yu-kun Xuan; Jian-xin Wang; Xiao-lin Zhang; Xiao-jun Yan (Frontiers in Marine Science, 2022)
Nowadays, diarrheic shellfish toxicity (DSP) toxin and microplastics (MPs) are commonly found in coastal waters worldwide. Due to their widespread use, their persistence and toxicity, they may induce adverse effects on Mytilus coruscus . However, the underlying toxic mechanisms of DSP and MPs on M. coruscus remain unclear. This study explored the physiological index and transcriptome change of the digestive gland of adult M. coruscus exposed for 3 days to polystyrene (PS) MPs (0.2 mg/L, 90-100 μm) and Prorocentrum lima alone or in combination. The results showed that the CAT activity and MDA content significantly increased, respiration rate and feeding rate significantly decreased. The combination of MPs and P. lima caused more structural damage to the rough surface endoplasmic reticulum and mitochondria in the digestive glands of M. coruscus . The transcriptome analysis showed that 485 and 220 genes were up- and down-regulated, respectively, after exposure to P. lima ; 1,989 up-regulated DEGs and 1,098 down-regulated DEGs were identified after exposure to MP treatment, and 1,004 up-regulated DEGs and 664 down-regulated DEGs were identified after exposure to the combination of P. lima and MPs. The DEGs were mainly enriched in the lysosome, mRNA surveillance pathway, carbon metabolism, the mTOR signaling pathway, the complement and coagulation cascades, and the TNF signaling pathway. The MP, P. lima exposure mainly induced the expression of RNA-binding protein musashi, serine/arginine repetitive matrix protein 1, low affinity immunoglobulin epsilon Fc receptor, toll-like receptor 2, caspase 7, calmodulin, E3 ubiquitin-protein ligase, serine/threonine-protein kinase PRP4, glutathione S-transferase, and heat shock 70 kDa protein. MPs and P. lima poison mainly influence the expression of RNA transport, immune related gene, apoptosis, signal related gene, and antioxidant gene change. The combination of MPs and P. lima has a synergistic toxic effect. This study provides a new insights into its physiological and molecular responses of M. coruscus to MPs and P. lima toxic exposure.

Machine learning-based models for predicting gas breakthrough pressure of porous media with low/ultra-low permeability - Cen Gao; Pu-Huai Lu; Wei-Min Ye; Zhang-Rong Liu; Qiong Wang; Yong-Gui Chen (Environmental Science and Pollution Research, 2022)

Molecular Characterization and Dietary Regulation of Glutaminase 1 (gls1) in Triploid Crucian Carp (Carassius auratus) - Yangbo Xiao; Rong Huang; Shenping Cao; Dafang Zhao; Zhuangwen Mao; Chuchu Xiao; Zhehua Xu; Xiaomei Zhou; Xinran Zhang; Yu Zhang; Jianzhou Tang; Junyan Jin; et al. (Fishes, 2022)
Kidney-type glutaminase, encoded by the gls1 gene, plays a critical role in glutamate production and improvement of meat flavor. In this study, a gls1 gene encoding 595 amino acids was cloned from triploid crucian carp (Carassius auratus) (TCC) and showed a high similarity with the gls1 gene found in Cyprinus carpio, Sinocyclocheilus rhinocerous and Puntigrus tetrazona. Comparing the abundance of gls1 in different tissues, we found its expression level in the brain and liver were significantly higher than that in heart, gut, kidney, spleen and muscle. gls1 expression in the brain reached the highest value. In addition, the expression levels of gls1 also appeared different in diurnal variation, with the highest expression seen at 9:00, while it was low at 3:00, 6:00, 15:00 and 24:00. Furthermore, dietary regulation of gls1 expression was investigated in our study. In each feeding trial, each diet was randomly assigned to triplicate tanks. Fish were fed one of the tested diets up to satiation twice daily. The results showed that gls1 expression increased in 32% protein group and decreased in 35–41% protein group. The results of different protein source experiments showed that the expression of gls1 gene in the mixed protein group (the control group) was significantly higher than that in the fish meal and soybean meal groups. Glutamate treatment revealed that appropriate concentrations (0.10 mg/mL in vivo and 2.00% in vitro) of glutamate remarkably improved the expression of gls1. Besides, diets supplemented with 0.80–1.60% lysine-glutamate dipeptide exhibited a down regulatory impact on gls1 expression. In conclusion, this study demonstrated that the expression of gls1 in TCC was increased by 32% protein diet, mixed protein source diet and diet with 2.00% glutamate concentration, while decreased by 0.80–1.60% lysine-glutamate dipeptide. The findings of this study provide a reference for the regulation of gls1 and have a potential application in the optimization of dietary formula in aquaculture.

QNE1 is a key flowering regulator determining the length of the vegetative period in soybean cultivars - Zhengjun Xia; Hong Zhai; Yanfeng Zhang; Yaying Wang; Lu Wang; Kun Xu; Hongyan Wu; Jinglong Zhu; Shuang Jiao; Zhao Wan; Xiaobin Zhu; Yi Gao; et al. (Science China Life Sciences, 2022)

The 2020–2021 prolonged La Niña evolution in the tropical Pacific - Chuan Gao; Maonan Chen; Lu Zhou; Licheng Feng; Rong-Hua Zhang (Science China Earth Sciences, 2022)

Plastid diversity and chromoplast biogenesis in differently coloured carrots: role of the DcOR3Leu gene - Yu-Min Zhang; Rong-Hua Wu; Lu Wang; Ya-Hui Wang; Hui Liu; Ai-Sheng Xiong; Zhi-Sheng Xu (Planta, 2022)

Manganese addition accelerates litter decomposition and alters litter mixing effects in the late stage in subtropical plantations of southern China - Pan-Pan Wu; Ling-Xin Jiang; Yan Zhang; Qi-Han Tu; Rong Mao (Plant and Soil, 2022)

Extracellular Mitochondria Activate Microglia and Contribute to Neuroinflammation in Traumatic Brain Injury - Chaonan Zhang; Chuan Liu; Fanjian Li; Mutian Zheng; Yafan Liu; Lei Li; Huaijin Yang; Shu Zhang; Chongjin Wang; Hongtao Rong; Hui Guo; Ying Li; et al. (Neurotoxicity Research, 2022)

Comprehensive transcriptome analysis unravels the crucial genes during adventitious root development induced by carbon monoxide in Cucumis sativus L. - Fahong Yun; Dengjing Huang; Meiling Zhang; Chunlei Wang; Yuzheng Deng; Rong Gao; Xuemei Hou; Zesheng Liu; Weibiao Liao (Molecular Biology Reports, 2022)

Silencing circ_0074371 inhibits the progression of sepsis-induced acute kidney injury by regulating miR-330-5p/ELK1 axis - Qiu-yuan Wang; Rong-rong Zhang; Long Cui; Ya-ping Sun (Mammalian Genome, 2022)

Impact of repeated intravenous infusions of umbilical cord–derived versus bone marrow–derived mesenchymal stem cells on angiogenesis in a pregnant experimentally induced deep venous thrombosis rat model - Xi Cheng; Weina Wang; Rong Du; Mu Zhang; Yuanyuan Xie; Weiwei Sun; Jingjing Ji; Baolan Sun; Yuquan Zhang (In Vitro Cellular & Developmental Biology - Animal, 2022)

Associations of essential element serum concentrations with autism spectrum disorder - Jing Wu; Dongfang Wang; Lailai Yan; Meixiang Jia; Jishui Zhang; Songping Han; Jisheng Han; Jingyu Wang; Xi Chen; Rong Zhang (Environmental Science and Pollution Research, 2022)

Effects and mechanism of ultrasound treatment on Chironomus kiiensis eggs - Bo-dong Liu; Hao-tao Dong; Hong-wei Rong; Rui-jian Zhang (Environmental Science and Pollution Research, 2022)

Improved lithium-ion batteries with coral-like anodes made of recycled spherical porous silicon coated with nitrogen-doped carbon - Zhao Zhang; Fengshuo Xi; Xiuhua Chen; Shaoyuan Li; Wenhui Ma; Zhao Ding; Tao Qu; Yongnian Dai; Rong Deng (Environmental Chemistry Letters, 2022)

Study on the Relationship Between Diet, Physical Health and Gut Microflora of Chinese College Students - Xiafen Hu; Jiaqi Guo; Jiadun Wang; Wanxin Liu; Xiaochen Xiang; Siyang Chen; Xinquan Li; Jinhan Tang; Wei Zhang; Hui Chen; Rong Shu; Qingming Wu; et al. (Current Microbiology, 2022)

Current Situation and Ecological Effects of Microplastic Pollution in Soil - Minggu Zhang; Miaomiao Tan; Rong Ji; Ronghui Ma; Chengliang Li (Reviews of Environmental Contamination and Toxicology, 2022)

Establishment of a novel myocarditis mouse model based on cyclosporine A - Tian Hao Zhao; Yi Xuan Jiang; Kai Qin Chen; Dan Qiu; Yan Zhe Xu; Chun Ye; Ting Ren; Bo Zhang; Bin Dai; Jue Hu; Jun Lu; Fang Liang Zhou; et al. (Genes & Genomics, 2022)

Integration of transcriptomics and metabolomics reveals pathways involved in MDSC supernatant attenuation of TGF-β1-induced myofibroblastic differentiation of mesenchymal stem cells - Yin Celeste Cheuk; Xinhao Niu; Yongxin Mao; Jiawei Li; Jiyan Wang; Shihao Xu; Yongsheng Luo; Weixi Wang; Xuanchuan Wang; Yi Zhang; Ruiming Rong (Cell and Tissue Research, 2022)

Infestation and distribution of chigger mites on Confucian white-bellied rat (Niviventer confucianus) in Southwest China - Yan-Ling Chen; Xian-Guo Guo; Wen-Yu Song; Tian-Guang Ren; Lei Zhang; Rong Fan; Cheng-Fu Zhao; Zhi-Wei Zhang; Wen-Ge Dong; Xiao-Bin Huang (Biologia, 2022)

Characteristics of antibiotic resistance gene distribution in rainfall runoff and combined sewer overflow - Xin-rong Pan; Lei Chen; Li-ping Zhang; Jian-e Zuo (Environmental Science and Pollution Research, 2022)

Ammonium induces oxidative stress, endoplasmic reticulum stress, and apoptosis of hepatocytes in the liver cell line of grass carp (Ctenopharyngodon idella) - Zhenyi Hu; Dengfeng Han; Tingting Zhang; Dapeng Li; Rong Tang (Environmental Science and Pollution Research, 2022)

Radiomics based on readout-segmented echo-planar imaging (RS-EPI) diffusion-weighted imaging (DWI) for prognostic risk stratification of patients with rectal cancer: a two-centre, machine learning study using the framework of predictive, preventive, and personalized medicine - Zonglin Liu; Yueming Wang; Fu Shen; Zhiyuan Zhang; Jing Gong; Caixia Fu; Changqing Shen; Rong Li; Guodong Jing; Sanjun Cai; Zhen Zhang; Yiqun Sun; et al. (EPMA Journal, 2022)
Background Currently, the rate of recurrence or metastasis (ROM) remains high in rectal cancer (RC) patients treated with the standard regimen. The potential of diffusion-weighted imaging (DWI) in predicting ROM risk has been reported, but the efficacy is insufficient. Aims This study investigated the potential of a new sequence called readout-segmented echo-planar imaging (RS-EPI) DWI in predicting the ROM risk of patients with RC using machine learning methods to achieve the principle of predictive, preventive, and personalized medicine (PPPM) application in RC treatment. Methods A total of 195 RC patients from two centres who directly received total mesorectal excision were retrospectively enrolled in our study. Machine learning methods, including recursive feature elimination (RFE), the synthetic minority oversampling technique (SMOTE), and the support vector machine (SVM) classifier, were used to construct models based on clinical-pathological factors (clinical model), radiomic features from RS-EPI DWI (radiomics model), and their combination (merged model). The Harrell concordance index (C-index) and the area under the time-dependent receiver operating characteristic curve (AUC) were calculated to evaluate the predictive performance at 1 year, 3 years, and 5 years. Kaplan‒Meier analysis was performed to evaluate the ability to stratify patients according to the risk of ROM. Findings The merged model performed well in predicting tumour ROM in patients with RC at 1 year, 3 years, and 5 years in both cohorts (AUC = 0.887/0.813/0.794; 0.819/0.795/0.783) and was significantly superior to the clinical model (AUC = 0.87 [95% CI: 0.80–0.93] vs. 0.71 [95% CI: 0.59–0.81], p = 0.009; C-index = 0.83 [95% CI: 0.76–0.90] vs. 0.68 [95% CI: 0.56–0.79], p = 0.002). It also had a significant ability to differentiate patients with a high and low risk of ROM (HR = 12.189 [95% CI: 4.976–29.853], p < 0.001; HR = 6.427 [95% CI: 2.265–13.036], p = 0.002). Conclusion Our developed merged model based on RS-EPI DWI accurately predicted and effectively stratified patients with RC according to the ROM risk at an early stage with an individualized profile, which may be able to assist physicians in individualizing the treatment protocols and promote a meaningful paradigm shift in RC treatment from traditional reactive medicine to PPPM.

Evolutions of upwelling and terrestrial organic matter input in the inner shelf of the East China Sea in the last millennium revealed by long-chain alkyl diols proxies - Chuanhui Song; Tianxiang Dang; Ting Zhang; Tiantian Ge; Rong Xiang; Lei Xing; Rui Bao; Yang Zhou; Rui Xiao; Baojin Wu (Frontiers in Marine Science, 2022)
Long-chain alkyl diols (LCDs) can be used as organic geochemical proxies for paleoceanographic change, especially in marginal sea areas where large volumes of sediments are deposited rapidly and continuously. However, little is known about the applicability and response on a millennium scale in relation with existing records in those sediments. We reconstruct changes in upwelling and terrestrial organic matter (OM) input in core sediments from the Zhejiang Fujian coastal station (T08) and Yangtze River Estuary station (T06) in the inner shelf of the East China Sea (ECS) over the last millennium, using the LCD based proxies: diol index 2 (DI-2), and FC 32 1,15-diol. Our results show that DI-2 values ([(C 28 +C 30 )1,14-diols]/([(C 28 +C 30 )1,13-diols]+[(C 28 +C 30 )1,14-diols])) at T08 decrease significantly during 600–400 yr BP but increase gradually after 400 yr BP. The FC 32 1,15-diol proxy ([C 32 1,15-diol]×100/([(C 28 +C 30 )1,13-diols]+[(C 30 +C 32 )1,15-diols])) at T06 shows marked fluctuations during 1000–800 yr BP, followed by a significant decline during 800–500 yr BP but a subsequent increase from 500 to 300 yr BP. We find that variations in DI-2 values are broadly consistent with changes in the strength of the East Asian Summer Monsoon (EASM) and the Kuroshio Current and are likely linked to changes in the frequency and intensity of the El Niño-Southern Oscillation (ENSO). The increased strength of the EASM causes greater offshore movement of the upper layer of seawater, which in turn triggers upwelling of bottom waters formed by Kuroshio subsurface waters. We find that variations in FC 32 1,15-diol proxy are controlled mainly by the East Asian Winter Monsoon (EAWM) and the Yangtze River discharge. By increasing the strength of the EAWM, southward transportation of material deposited in the estuary of the Yangtze River by the ECS coastal currents is promoted. In addition, we synthesize records of other organic geochemical indicators nearby core sediments in the ECS; these records emphasize the importance of reconstructing the evolutionary history of upwelling and subdividing the relative inputs of terrestrial OM. Our study provides a new means for reconstructing the evolution of upwelling and terrestrial OM input in the inner shelf of the ECS over the last millennium.

Plantlet regeneration from apple (Malus × domestica Borkh.) anther culture derived embryos - Chunfen Zhang; Shu Deng; Qiufen Cao; Sadao Komori; Rong Xiao (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

Plasma Exo-miRNAs Correlated with AD-Related Factors of Chinese Individuals Involved in Aβ Accumulation and Cognition Decline - Lifang Wang; Hefu Zhen; Yuzhe Sun; Shuang Rong; Benchao Li; Zhijie Song; Zhili Liu; Zhiming Li; Jiahong Ding; Huanming Yang; Xiuqing Zhang; Haixi Sun; et al. (Molecular Neurobiology, 2022)
Numerous studies have investigated the risk factors of Alzheimer’s disease (AD); however, AD-risk factors related miRNAs were rarely reported. In this study, AD-risk factor related miRNAs of 105 Chinese individuals (45 AD patients and 60 cognitively normal controls) were investigated. The results showed that Hsa-miR-185-5p, Hsa-miR-20a-5p, and Hsa-miR-497-5p were related to AD and education, Hsa-miR-185-5p, Hsa-miR-181c-5p, Hsa-miR-664a-3p, Hsa-miR-27a-3p, Hsa-miR-451a, and Hsa-miR-320a were related to AD and depression. Target prediction of above miRNAs showed that these miRNAs were involved in the generation and clearance of amyloid-beta (Aβ), important molecules related to cognition, and disease-activated microglia response to AD. It is worth noting that Hsa-miR-185-5p was related to both education and depression, whose decreased expression pattern in AD patients was alleviated by education and enhanced by depression, and participates in Aβ generation and accumulation. Our results indicated that certain education and depression factors can contribute to AD progression by modulating miRNA expression, implying that preventive interventions might alter AD progression in Chinese patients.

Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice - Bo Yang; Zhan Gao; Qi-Shuang Li; Xiang-Ye Zhang; Lan Song; Yi-Ni Wang; Xin-Yue Wang; Lin-Lin Ji; Hong-Liang Xu; Hui Xie; Fu-Kai Feng; Xiao-Ping Li; et al. (Inflammation Research, 2022)

Homozygous missense mutation in CCDC155 disrupts the transmembrane distribution of CCDC155 and SUN1, resulting in non-obstructive azoospermia and premature ovarian insufficiency in humans - Huan Wu; Xin Zhang; Rong Hua; Yuqian Li; Li Cheng; Kuokuo Li; Yiyuan Liu; Yang Gao; Qunshan Shen; Guanxiong Wang; Mingrong Lv; Yuping Xu; et al. (Human Genetics, 2022)

Statin contribution to middle cerebral artery blood flow velocity in older adults at risk for dementia - Stacey E. Aaron; Tsubasa Tomoto; Rong Zhang; John P. Thyfault; Eric D. Vidoni; Robert N. Montgomery; Jeffrey M. Burns; Sandra A. Billinger (European Journal of Applied Physiology, 2022)

Occurrence and damage of epidemic fungal diseases in middle and late stages of sugarcane growth in Yunnan Province of China - Wen-Feng Li; Xiao-Yan Wang; Hong-Li Shan; Rong-Yue Zhang; Yin-Hu Li; Wen-Jie Lu; Ying-Kun Huang (European Journal of Plant Pathology, 2022)

Concentrations, distribution, and risk assessment of endosulfan residues in the cotton fields of northern Xinjiang, China - Yang Zhang; Rong Guo; Yang Li; Mingyu Qin; Jingquan Zhu; Zhihong Ma; Yong Ren (Environmental Geochemistry and Health, 2022)

Cortical connectivity gradients and local timescales during cognitive states are modulated by cognitive loads - Heming Zhang; Rong Zhao; Xin Hu; Sihai Guan; Daniel S. Margulies; Chun Meng; Bharat B. Biswal (Brain Structure and Function, 2022)

A new numerical model of ring shear tester for shear band soil considering friction-induced thermal pressurization - Neng-hao Zhao; Kun Song; Rong-tang Zhang; Qing-lin Yi (Journal of Mountain Science, 2022)

Local temperature increases reduce soil microbial residues and carbon stocks - Xiao‐Min Zeng; Jiao Feng; Dai‐Lin Yu; Shu‐Hai Wen; Qianggong Zhang; Qiaoyun Huang; Manuel Delgado‐Baquerizo; Yu‐Rong Liu (Global Change Biology, 2022)
Warming is known to reduce soil carbon (C) stocks by promoting microbial respiration, which is associated with the decomposition of microbial residue carbon (MRC). However, the relative contribution of MRC to soil organic carbon (SOC) across temperature gradients is poorly understood. Here, we investigated the contribution of MRC to SOC along two independent elevation gradients of our model system (i.e., the Tibetan Plateau and Shennongjia Mountain in China). Our results showed that local temperature increases were negatively correlated with MRC and SOC. Further analyses revealed that rising temperature reduced SOC via decreasing MRC, which helps to explain future reductions in SOC under climate warming. Our findings demonstrate that climate warming has the potential to reduce C sequestration by increasing the decomposition of MRC, exacerbating the positive feedback between rising temperature and CO 2 efflux. Our study also considered the influence of multiple environmental factors such as soil pH and moisture, which were more important in controlling SOC than microbial traits such as microbial life‐style strategies and metabolic efficiency. Together, our work suggests an important mechanism underlying long‐term soil C sequestration, which has important implications for the microbial‐mediated C process in the face of global climate change.

Nitrogen repression of deoxynivalenol biosynthesis is mediated by Mep2 ammonium permease in Fusarium graminearum - Yuting Hu; Rui Hou; Zeyi Wang; Weiwei Zhang; Jin‐Rong Xu (Environmental Microbiology, 2022)
Fusarium graminearum is an important wheat pathogen and a producer of deoxynivalenol (DON). Biosynthesis of DON is suppressed by ammonium and induced by arginine and polyamines. To better understand ammonium repression of DON biosynthesis, in this study, we functionally characterized three ammonium permease ( MEP ) genes in F. graminearum . All the mep deletion mutants were normal in growth on V8 agar. Whereas deletion of MEP1 had no detectable phenotypes, the mep2 and mep3 mutants had defects in hyphal growth under ammonium limiting conditions and infection of wheat heads, with the latter having less severe defects. Deletion of MEP2 but not MEP3 affected nitrogen repression of DON biosynthesis and genes involved in nitrate metabolism. The mep2 mep3 double mutant had more severe defects in nitrogen repression than the mep2 mutant and was defective in ascospore releasing. Mutant alleles of MEP2 with truncated C‐terminal cytoplasmic tail (CT) failed to complement the mep2 mutant. Expression of a dominant active allele of RAS2 partially rescued the defects of mep2 in nitrogen repression. Taken together, these results suggest that Mep2 acts as the major sensor of ammonium availability in F. graminearum and its CT region functions in nitrogen repression via RAS2 and downstream signalling pathways.

Biocrust diazotrophs and bacteria rather than fungi are sensitive to chronic low N deposition - Xiaoying Rong; Xiaobing Zhou; Xiangzhen Li; Minjie Yao; Yongxing Lu; Peng Xu; Benfeng Yin; Yonggang Li; Zachary T. Aanderud; Yuanming Zhang (Environmental Microbiology, 2022)
Anthropogenic long‐term nitrogen (N) deposition may dramatically impact biocrusts due to the overarching N limitation of soil biota in deserts. Even low levels of N may reach a critical loading threshold altering biocrust constituents and function. To identify the impact of chronic and continuous low levels of N deposition on biocrusts, we created a realistic gradient mirroring anthropogenic N addition rate (2:1 NH 4 + : NO 3 − rates: 0.3, 0.5, 1.0, 1.5, 3 g N m −2 yr −1 ) and measured the response of bacteria and fungi within cyanobacterial‐dominated biocrusts over 8 years in a temperate desert, the Gurbantunggut Desert, China. We found that once N deposition reached 1.5 g N m −2 yr −1 biocrust bacterial communities, including diazotrophs, were altered while no such tipping point existed for fungi. Above the threshold, bacterial richness was enhanced, the relative abundance of Chloroflexi, FBP and Gemmatimonadetes was elevated, and diazotrophs shifted from being dominated by Nostocaceae and Scytonemataceae (Cyanobacteria) to free‐living Bradyrhizobiaceae (Alphaproteobacteria). Alternatively, the relative recovery of a few fungal species within the Lecanorales, Pleosporales and Verrucariales became either enriched or diminished due to N deposition. The chronic addition of N resulted in a dense and interconnected bacterial co‐occurrence network that accentuated a functional shift from networks dominated by phototrophic species within the Nostocaceae, Xenococcaceae, Phormidiaceae and Scytonemataceae (Cyanobacteria) to ammonia‐oxidizing species within the Nitrosomonadaceae (Betaproteobacteria) and nitrifying bacteria [i.e. Nitrospiraceae (Nitrospirae)]. Based on structural equation models, the effects of N additions on biocrust constituents were imposed through indirect effects on pH, soil electrical conductivity and ammonium concentrations. In summary, biocrust constituents are generally insensitive to chronic low levels of N depositions until rates reach above 1.5 g N m −2 yr −1 with diazotrophs being the most sensitive biocrust constituents followed by bacteria and finally fungi. Ultimately once the threshold is reached N deposition favours biocrust constituents utilizing inorganic N and other C sources over relying on phototrophic and/or N‐fixing cyanobacteria for C and N.

HOXD11 upregulates JAM-A and exerts oncogenic properties via NF-κB signaling pathway in esophageal squamous cell carcinoma - Rong Xiong; Qiongxian Long; Xuqian Zhang; Jun Xu; Yanqun Liu; Li Xiong; Siyun Yang; Gang Feng; Guiqing Song; Kang Liu (Human Cell, 2022)

Preparation of Pinocembrin-Loaded F127/MPEG-PDLLA Polymer Micelles and Anti-Osteoporotic Activity - Xia Cao; Qing He; Michael Adu-Frimpong; Xinyi Shen; Wanjing Rong; Xiaoxiao Li; Jian Zhang; Xiaoli Xia; Feng Shi; Hao Ji; Elmurat Toreniyazov; Qilong Wang; et al. (AAPS PharmSciTech, 2022)

Induced mutation in ELONGATED HYPOCOTYL5 abolishes anthocyanin accumulation in the hypocotyl of pepper - Rong Chen; Can Yang; Hu Gao; Chunmei Shi; Zhiying Zhang; Guangyu Lu; Xinyan Shen; Yaping Tang; Feng Li; Yongen Lu; Bo Ouyang (Theoretical and Applied Genetics, 2022)

Isolation and Analysis of Reverse Transcriptase of Ty1-copia-Like Retrotransposons in Sugarcane - Jun-Xian Liu; Jing Liu; Tai-Yi Yang; Li-Min Liu; Li-Hang Qiu; Yi-Jing Gao; Wei-Xing Duan; Jing-Chao Lei; Hong-Jian Liu; Rong-Hua Zhang; Wei-Zhong He; Song Li; et al. (Sugar Tech, 2022)

Abscisic acid induces the expression of AsKIN during the recovery period of garlic cryopreservation - Xiaodong Xing; Min Liu; Fangling Jiang; Rong Zhou; Yunhe Bai; Hanyu Wei; Deng Zhang; Jingjing Wei; Zhen Wu (Plant Cell Reports, 2022)

Tumor necrosis factor-α coordinates with transforming growth factor-β1 to induce epithelial-mesenchymal transition and migration via the NF-κB/NOX4 pathway in bronchial epithelial cells - Ke Li; Rong Zhou; Mingze Ma; Chaomei Jin; Linlin Jiao; Siyu Zhang; Mei Tian; Fang Zhou (Molecular Biology Reports, 2022)

Phosphorylation of Truncated Tau Promotes Abnormal Native Tau Pathology and Neurodegeneration - Longfei Li; Yanli Jiang; Gang Wu; Yacoubou Abdoul Razak Mahaman; Dan Ke; Qun Wang; Bin Zhang; Jian-Zhi Wang; Hong-Lian Li; Rong Liu; Xiaochuan Wang (Molecular Neurobiology, 2022)

Tetramethylpyrazine protects neural stem cells against sevoflurane-induced toxicity through Akt/GSK-3β pathway - Yan Feng; Kui Wang; Ning Wang; Pengyu Jia; Lei Zhang; Haozheng Yuan; Pan Lu; Yang Lu; Hong Zhang; Rong Li; Yan Zhang; Qianqian Li; et al. (Metabolic Brain Disease, 2022)

Histone modification in podocyte injury of diabetic nephropathy - Simeng Wang; Xinyu Zhang; Qinglian Wang; Rong Wang (Journal of Molecular Medicine, 2022)

Potential therapeutic strategies for myocardial infarction: the role of Toll-like receptors - Sumra Komal; Nimrah Komal; Ali Mujtaba; Shu-Hui Wang; Li-Rong Zhang; Sheng-Na Han (Immunologic Research, 2022)

Screening of microRNA and mRNA related to secondary hair follicle morphogenesis and development and functional analysis in cashmere goats - Fangzheng Shang; Yu Wang; Rong Ma; Youjun Rong; Min Wang; Zhihong Wu; Erhan Hai; Jianfeng Pan; Lili Liang; Zhiying Wang; Ruijun Wang; Rui Su; et al. (Functional & Integrative Genomics, 2022)
microRNA (miRNA) is a type of endogenous short-chain non-coding RNA with regulatory function found in eukaryotes, which is involved in the regulation of a variety of cellular and biological processes. However, the research on the development of cashmere goat secondary hair follicles is still relatively scarce. In this study, small RNA libraries and mRNA libraries of 45 days, 55 days, 65 days, and 75 days of fetal skin of cashmere goats were constructed, and the constructed libraries were sequenced using Illumina Hiseq4000, and the expression profiles of miRNA and mRNA in cashmere goat fetal skin were obtained. The differentially expressed miRNAs and mRNAs in six control groups were identified and the qRT-PCR experiment shows that the sequencing results are accurate. Sixty-six miRNAs related to secondary hair follicle development were screened, and used TargetScan and miRanda to predict 33 highly expressed miRNA target genes. At the same time, 664 mRNAs related to the development of secondary hair follicles were screened, and GO enrichment and KEGG pathway analysis were performed. It was found that some miRNA target genes were consistent with the screening results of mRNAs related to secondary hair follicle development and were enriched in Notch signaling pathway, TGF-β signaling pathway. Therefore, miR-145-5p-DLL4, miR-27b-3p-DLL4, miR-30e-5p-DLL4, miR-193b-3p-TGF-β1, miR-181b-5p-NOTCH2, and miR-103-3p-NOTCH2 regulatory network related to the development of secondary hair follicles were constructed and the results of dual-luciferase reporter gene assay indicated that there is a targeted relationship between chi-miR-30e-5p and DLL4, which will provide a basis for molecular mechanism of miRNA-mRNA in the development of the hair follicles in cashmere goats.

Metabacillus rhizolycopersici sp. nov., Isolated from the Rhizosphere Soil of Tomato Plants - Rong Ma; Shan-Wen He; Xing Wang; Kyu Kyu Thin; Ji-Gang Han; Xiao-Xia Zhang (Current Microbiology, 2022)

Hybrid brain model accurately predict human procrastination behavior - Zhiyi Chen; Rong Zhang; Jiawei Xie; Peiwei Liu; Chenyan Zhang; Jia Zhao; Justin Paul Laplante; Tingyong Feng (Cognitive Neurodynamics, 2022)

Assessing the Impact of Atrazine on the Availability of Arsenic in Soils Using DGT Technique - Yanying Li; Liying Yan; Qiuyu Rong; Jun Luo; Hao Zhang; Kevin C. Jones (Bulletin of Environmental Contamination and Toxicology, 2022)

Prediction model for disc cutter wear during hard rock breaking based on plastic removal abrasiveness mechanism - Lei She; She-rong Zhang; Chao Wang; Zheng-qiao Wu; Lun-chuang Yu; Li-xin Wang (Bulletin of Engineering Geology and the Environment, 2022)

Mechanism of progressive failure of a slope with a steep joint under the action of freezing and thawing: model test - Cong Li; Rong-tang Zhang; Jie-bing Zhu; Bo Lu; Xiao-ke Shen; Xiao-wei Wang; Jie-sheng Liu; Liang-liang Wu; Xin-zhou Zhang (Journal of Mountain Science, 2022)

Outcrop modeling of flow units and reductant within a sandstone uranium reservoir in the Zhiluo Formation, eastern Ordos Basin: implications for the uranium mineralization mechanism - Zhenpeng Tao; Liqun Wu; Yangquan Jiao; Hui Rong; Fan Zhang; Xuesong Lu (Geosciences Journal, 2022)

Experimental Investigation on Behavior of Single-Helix Anchor in Sand Subjected to Uplift Cyclic Loading - Dongxue Hao; Jianyi Che; Rong Chen; Xin Zhang; Chi Yuan; Xichao Chen (Journal of Marine Science and Engineering, 2022)
Helical anchors have been widely used in geotechnical engineering due to their large uplift resistance. However, the current knowledge of the cyclic performance of helical anchors is still insufficient. Consequently, a series of small-scale model tests are carried out in sand to investigate the influences of embedment ratio, sand compactness and the cyclic parameters on the monotonic, cyclic and post-cyclic performance of single-helix anchors. The tests results indicate that the single-helix anchors with optimal embedment ratio still exhibit a relatively high uplift capacity after suffering cyclic load. The cyclic frequency has the greatest influence on the accumulated displacement, and the influence of amplitude is relatively greater than that of the mean cyclic load. The anchors in dense sand exhibit better performance to resist pullout than those in medium–dense sand under the same cyclic parameter ratios. Moreover, the correlation of post-cyclic uplift capacity and displacement after cyclic loading as well as the possible influence of the upward displacement on the sand flow above the helix are discussed.

Changes in amino acid and fatty acid composition during early development in cobia (Rachycentron canadum) - Jian-sheng Huang; Rong-xin Li; Rui-tao Xie; You-ming Chen; Jian-dong Zhang; Eric Amenyogbe; Gang Chen (Frontiers in Marine Science, 2022)
An estimation of the utilization of endogenous nutrients from the yolk sac that occurs during embryonic and early larval development can be a valuable approach to studying the nutritional requirements of fish larvae. In this study, fertilized eggs, embryos (before the membrane, 24 hours after fertilization), newly-hatched larvae (0-d-old), and open-mouthed larvae (3-day-old, unfed rotifers) samples of cobia ( Rachycentron canadum ) were collected to determine the amino acid and fatty acid profiles. Crude protein composition varies significantly for cobia during the different stages of development. The total amino acids, except for lysine(Lys), histidine (His), methionine(Met), serine(Ser), and glycine(Gly), had no significant change in the early development stage ( P > 0.05); the content of other six essential amino acids (EAA) and six non-essential amino acids (NEAA) was consistent with the changing trend of total essential amino acid. From hatching newly hatched larvae to open-mouthed larvae, except for Leu, Phe and Ser, decreased significantly ( P <0.05). From the utilization rate of FAA, the utilization rate of Lys and Leu was the highest (60.26%) and (52.21%) in the embryonic and endogenous nutritional stages, respectively. The water content of the open-mouthed larvae of cobia was significantly higher than that of the fertilized eggs, embryos, and newly hatched larvae ( P < 0.05). Three kinds of saturated fatty acids (SFA), five kinds of monounsaturated fatty acids (MUFA), and eight kinds of polyunsaturated fatty acids (PUFA) were detected in the dry samples of each developmental stage. Based on these results, juvenile cobia can thrive with a wide range of crude protein concentrations. Further refinement of commercial cobia production feeds would have beneficial consequences for economic and environmental concerns due to the positive impacts of optimizing the protein component as well as the ability to maintain the rapid growth rates. The results show that the larval development of cobia needs to consume large amounts of n3PUFA (especially DHA and EPA) to improve the larvae’s survival rate. Research methods will always have limitations when evaluating the relationship between early life nutrition interventions and well-being outcomes later in life. This study provides essential information regarding cobia larvae’s fatty acid requirements.

Fast forward modeling of muon transmission tomography based on model voxelization ray energy loss projection - Rong-Qing Zhang; Zhen-Zhu Xi; Wei Liu; He Wang; Zi-Yan Yang (Applied Geophysics, 2022)

Drivers of foliar 15 N trends in southern China over the last century - Songbo Tang; Jianfeng Liu; Frank S. Gilliam; Peter Hietz; Zhiheng Wang; Xiankai Lu; Feiyan Zeng; Dazhi Wen; Enqing Hou; Yuan Lai; Yunting Fang; Ying Tu; et al. (Global Change Biology, 2022)
Foliar stable nitrogen (N) isotopes (δ 15 N) generally reflect N availability to plants and have been used to infer about changes thereof. However, previous studies of temporal trends in foliar δ 15 N have ignored the influence of confounding factors, leading to uncertainties on its indication to N availability. In this study, we measured foliar δ 15 N of 1811 herbarium specimens from 12 plant species collected in southern China forests from 1920 to 2010. We explored how changes in atmospheric CO 2 , N deposition and global warming have affected foliar δ 15 N and N concentrations ([N]) and identified whether N availability decreased in southern China. Across all species, foliar δ 15 N significantly decreased by 0.82‰ over the study period. However, foliar [N] did not decrease significantly, implying N homeostasis in forest trees in the region. The spatiotemporal patterns of foliar δ 15 N were explained by mean annual temperature (MAT), atmospheric CO 2 (), atmospheric N deposition, and foliar [N]. The spatiotemporal trends of foliar [N] were explained by MAT, temperature seasonality, , and N deposition. N deposition within the rates from 5.3 to 12.6 kg N ha −1 year −1 substantially contributed to the temporal decline in foliar δ 15 N. The decline in foliar δ 15 N was not accompanied by changes in foliar [N] and therefore does not necessarily reflect a decline in N availability. This is important to understand changes in N availability, which is essential to validate and parameterize biogeochemical cycles of N.

Complex impacts of hydraulic fracturing return fluids on soil microbial community respiration, structure and functional potentials - Cheng Zhong; Camilla L. Nesbø; Konstantin von Gunten; Yifeng Zhang; Xiaoqing Shao; Rong Jin; Kurt O. Konhauser; Greg G. Goss; Jonathan W. Martin; Yuhe He; Pei‐Yuan Qian; Brian D. Lanoil; et al. (Environmental Microbiology, 2022)
Summary The consequences of soils exposed to hydraulic fracturing (HF) return fluid, often collectively termed flowback and produced water (FPW), are poorly understood, even though soils are a common receptor of FPW spills. Here, we investigate the impacts on soil microbiota exposed to FPW collected from the Montney Formation of western Canada. We measured soil respiration, microbial community structure and functional potentials under FPW exposure across a range of concentrations, exposure time and soil types (luvisol and chernozem). We find that soil type governs microbial community response upon FPW exposure. Within each soil, FPW exposure led to reduced biotic soil respiration, and shifted microbial community structure and functional potentials. We detect substantially higher species richness and more unique functional genes in FPW‐exposed soils than in FPW‐unexposed soils, with metagenome‐assembled genomes (e.g. Marinobacter persicus ) from luvisol soil exposed to concentrated FPW being most similar to genomes from HF/FPW sites. Our data demonstrate the complex impacts of microbial communities following FPW exposure and highlight the site‐specific effects in evaluation of spills and agricultural reuse of FPW on the normal soil functions.

Optimization of the Hydrodynamic Performance of a Double-Vane Otter Board Based on Orthogonal Experiments - Lei Wang; Xun Zhang; Rong Wan; Qingchang Xu; Guangrui Qi (Journal of Marine Science and Engineering, 2022)
An orthogonal experiment was conducted to study the effects of the aspect ratio, camber of the fore wing, and gap ratio of front and rear wing panels on the hydrodynamic performance of double-vane otter boards. The design of the orthogonal experiment comprised three factors (each having three levels), namely the aspect ratio (1.0, 1.5, and 2.0), camber (0.12, 0.14, and 0.16), and gap ratio (0.25, 0.30, and 0.35), the drag coefficient Cx and the lift coefficient Cy of nine otter board models obtained in a wind tunnel experiment, and the lift–drag ratio K obtained by calculation. The lift–drag ratio for a working angle of attack of 30° was selected as the inspection index, and the experimental data were analyzed in an orthogonal design-direct analysis. Analysis of each factor revealed that the optimal level combination of factors was A3B3C3 and that the decreasing order of the effects of the factors was A (aspect ratio) > B (gap ratio) > C (camber). The orthogonal experiment thus obtained an optimal otter board in terms of the aspect ratio (2.0), fore wing camber (0.16), and gap ratio (0.35), with the aspect ratio having the greatest effect on performance. The hydrodynamic performances of the otter board with the optimized structure and another otter board model were compared in numerical simulation, which verified the correctness of the analysis results. The experimental results provide a reference for the optimal design of the double-vane otter board.

Physiology, metabolism, antibiotic resistance, and genetic diversity of Harveyi clade bacteria isolated from coastal mariculture system in China in the last two decades - Hao Kang; Yongxiang Yu; Meijie Liao; Yingeng Wang; Guanpin Yang; Zheng Zhang; Bin Li; Xiaojun Rong; Chunyuan Wang (Frontiers in Marine Science, 2022)
Vibrio bacteria, particularly members of the Harveyi clade, are the most important pathogens of aquatic organisms that cause significant economic losses in the world. It is difficult to provide specific data on taxa of the Harveyi clade for biological research and prevention strategies. Therefore, we conducted an extensive phenotypic and antibiotic resistance study, as well as phylogenetic and molecular typing of 192 isolates of the Harveyi clade collection from 2000 to 2020 with a typical interannual difference from a coastal area in China. The isolates had a significant interspecific genetic and antibiotic resistance diversity. Based on the multilocus sequence analysis (MLSA) of housekeeping genes ( gyrB , pyrH , recA , and atpA ), 192 Harveyi clade isolates were rapidly and accurately classified into 10 species. The population of these isolates was composed of 95 sequence types (STs), of which 92 STs were newly identified, indicating a high degree of genetic diversity. ST327 ranked first, accounting for 11.5% of the total number of isolates (22 out of 192), followed by ST215 with 6.25%, while 63 STs included single isolates. At the metabolic level, the physiological and biochemical experiments revealed that all the Harveyi clade isolates were positive for oxidase and negative for melibiose. The isolates showed a varied tolerance to 11 antibiotics. No isolates were resistant to neomycin. The percentages of sulfadimidine-resistant strains (61 out of 192), sulfadiazine (44 out of 192), sulfamonomethoxine (44 out of 192), sulfamethoxazole (33 out of 192), thiamphenicol (34 out of 192), ciprofloxacin (52 out of 192), and enrofloxacin (31 out of 192) were 31.77%, 22.92%, 22.92%, 17.19%, 17.71%, 27.08%, and 16.15%, respectively. A proportion of 61.8% of the isolates presented a multiple antibiotic resistance index (MARI) lower than 0.1, indicating that the risk of antibiotic resistance transmission of most of the Harveyi clade is low in mariculture systems in China. These results provide substantial data to support further studies on the identification and genetic and metabolic diversity of Harveyi clade isolates in mariculture systems in China.

Antifungal and insecticidal activities of rhein derivatives: synthesis, characterization and preliminary structure–activity relationship studies - Xiang Zhu; Shunshun Chen; Yan Zheng; Yong Zhang; Tom Hsiang; Rong Huang; Jingwei Qi; Tian Gan; Yue Chang; Junkai Li (Natural Product Research, 2022)

Correction to: Higher sequestration of wheat versus maize crop carbon in soil under rotations - Zheng-Rong Kan; Shou-Wei Han; Wen-Xuan Liu; Xin Zhao; Rattan Lal; Hai-Lin Zhang (Environmental Chemistry Letters, 2022)

Analysis of the atmospheric direct dynamic source for the westerly extended WPSH and record-breaking Plum Rain in 2020 - Yuheng Zhao; Jianbo Cheng; Guolin Feng; Rong Zhi; Zhihai Zheng; Zengping Zhang (Climate Dynamics, 2022)

Protective Effect of Selenium on the Oxidative Damage of Kidney Cells Induced by Sodium Nitrite in Grass Carp (Ctenopharyngodon idellus) - Tingting Zhang; Chaorui Yao; Zhenyi Hu; Dapeng Li; Rong Tang (Biological Trace Element Research, 2022)

Heterologous expression of ZmNF-YA12 confers tolerance to drought and salt stress in Arabidopsis - Tongtong Zhang; Dengyu Zheng; Chun Zhang; Zhongyi Wu; Rong Yu; Zhongbao Zhang (Plant Biotechnology Reports, 2022)

Runoff projections of the Qinling Mountains and their impact on water demand of Guanzhong region in Northwest China - Zhao-peng Zhang; Ke-qin Duan; Huan-cai Liu; Ya-li Meng; Rong Chen; Da-wei Li; Shuang-shuang Li (Journal of Mountain Science, 2022)

Identifying Supercooled Liquid Water in Cloud Based on Airborne Observations: Correlation of Cloud Particle Number Concentration with Icing Probability and Proportion of Spherical Particles - Yuquan Zhou; Can Song; Miao Cai; Siyao Liu; Yang Gao; Rong Zhang (Journal of Meteorological Research, 2022)

Antimicrobial Resistance and Genotype Characteristics of Vibrio scophthalmi Isolated from Diseased Mariculture Fish Intestines With Typical Inter-Annual Variability - Yongxiang Yu; Xiao Liu; Yingeng Wang; Meijie Liao; Miaomiao Tang; Xiaojun Rong; Chunyuan Wang; Bin Li; Zheng Zhang (Frontiers in Marine Science, 2022)
As an intestinal organism settled long-term within the gut of marine fish, Vibrio scophthalmi is a potential object for the bacterium genetic variation and adaptation research. The genetic diversity, antimicrobial resistance phenotype, and genotype of 33 V. scophthalmi isolated from diseased marine fish intestines between 2002 and 2020 were evaluated. The results showed that all isolates were frequently resistant to penicillins, cephalosporins, aminoglycosides, and macrolides and displayed multidrug-resistant (MDR) phenotype in vitro . Thirty percent of isolates were resistant to more than 20 different drugs. The average insensitive (resistant and intermediate) rate of V. scophthalmi isolates was 49.5%~81.8% between 2002 and 2020, but the t-test revealed that there was no significant difference in the drug-resistance rate of V. scophthalmi isolates with typical interannual variability. Eleven antimicrobial resistance genes ( strB , strA , ant(3 ˝)-I , mphA , blaPSE , qnrS , tetC , tetE , tetM , tetS , and int1 ) were detected in these isolates, but the antimicrobial resistance phenotypes and genotypes of these isolates were not consistent. Enterobacterial repetitive intergenic consensus polymerase chain reaction (ERIC-PCR) analysis indicated that 33 isolates could be divided into two clusters (G1 and G3) and two single isolates (G2 and G4), and the G2 cluster was isolated from South Sea C. undulates with typical geographical species differences. There was no significant correlation between the drug susceptibility and the genetic types of V. scophthalmi isolates. The results reveal the mismatch phenomenon between antimicrobial resistance and genotype of inherent V. scophthalmi in the marine fish intestines, and the antimicrobial susceptibility isolates might be a potential risk source for storage and transmission of resistance genes.

Factors Influencing Alzheimer’s Disease Risk: Whether and How They are Related to the APOE Genotype - Rong Zhang; Xiaojiao Xu; Hang Yu; Xiaolan Xu; Manli Wang; Weidong Le (Neuroscience Bulletin, 2022)
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease featuring progressive cognitive impairment. Although the etiology of late-onset AD remains unclear, the close association of AD with apolipoprotein E (APOE), a gene that mainly regulates lipid metabolism, has been firmly established and may shed light on the exploration of AD pathogenesis and therapy. However, various confounding factors interfere with the APOE -related AD risk, raising questions about our comprehension of the clinical findings concerning APOE . In this review, we summarize the most debated factors interacting with the APOE genotype and AD pathogenesis, depict the extent to which these factors relate to APOE -dependent AD risk, and discuss the possible underlying mechanisms.

MoS2 boosts the Fe2+/PMS process for carbamazepine degradation - Huan Peng; Rong Chen; Ningyao Tao; Yangyi Xiao; Chenxing Li; Tuqiao Zhang; Miaomiao Ye (Environmental Science and Pollution Research, 2022)

Recognition of the Multi-class Schizophrenia Based on the Resting-State EEG Network Topology - Fali Li; Lin Jiang; Yuanyuan Liao; Cunbo Li; Qi Zhang; Shu Zhang; Yangsong Zhang; Li Kang; Rong Li; Dezhong Yao; Gang Yin; Peng Xu; et al. (Brain Topography, 2022)

Associations Between Fundus Types and Clinical Manifestations in Patients with RDH12 Gene Mutations - Jing Jin; Liang Liang; Kun Jin; Hai-jiang Zhang; Rong Liu; Yin Shen (Brain Topography, 2022)

Selenium Deficiency Induces Autophagy in Chicken Bursa of Fabricius Through ChTLR4/MyD88/NF-κB Pathway - Ruili Zhang; Qing Liu; Rong Guo; Di Zhang; Yang Chen; Guangxing Li; Xiaodan Huang (Biological Trace Element Research, 2022)

Dynamic p-y curves for vertical and batter pile groups in liquefied sand - Jian Zhang; Yurun Li; Xian Rong; Yan Liang (Earthquake Engineering and Engineering Vibration, 2022)

Impact of heat stress on milk yield, antioxidative levels, and serum metabolites in primiparous and multiparous Holstein cows - Xue Chen; Jia Nan Dong; Ji Ye Rong; Jun Xiao; Wei Zhao; Natnael D. Aschalew; Xue Feng Zhang; Tao Wang; Gui Xin Qin; Zhe Sun; Yu Guo Zhen (Tropical Animal Health and Production, 2022)

An improved hybrid bream derived from a hybrid lineage of Megalobrama amblycephala (♀)×Culter alburnus (♂) - Dingbin Gong; Min Tao; Lihui Xu; Fangzhou Hu; Zehong Wei; Shi Wang; Yude Wang; Qingfeng Liu; Chang Wu; Kaikun Luo; Chenchen Tang; Rong Zhou; et al. (Science China Life Sciences, 2022)

Bmal1- and Per2-mediated regulation of the osteogenic differentiation and proliferation of mouse bone marrow mesenchymal stem cells by modulating the Wnt/β-catenin pathway - Jiawen Zheng; Lanxin Zhang; Zhen Tan; Qing Zhao; Xiaoyu Wei; Yuqing Yang; Rong Li (Molecular Biology Reports, 2022)

Prediction of the sea buckthorn AQP gene structure and its spatiotemporal expression pattern under drought stress - Dan Zhang; Nanxiang Yang; Jiawei Dong; Cheng Wang; Qiangfeng Li; Rong Wang; Zhipeng Feng; Dejuan Xie; Guisheng Ye; Yuhua Ma (Journal of Plant Biochemistry and Biotechnology, 2022)

Brain 5-HT2A receptor binding and its neural network related to behavioral inhibition system - Kazuho Kojima; Shigeki Hirano; Yasuyuki Kimura; Chie Seki; Yoko Ikoma; Keisuke Takahata; Takehito Ito; Keita Yokokawa; Hiroki Hashimoto; Kazunori Kawamura; Ming-Rong Zhang; Hiroshi Ito; et al. (Brain Imaging and Behavior, 2022)
The tendency to avoid punishment, called behavioral inhibition system, is an essential aspect of motivational behavior. Behavioral inhibition system is related to negative affect, such as anxiety, depression and pain, but its neural basis has not yet been clarified. To clarify the association between individual variations in behavioral inhibition system and brain 5-HT 2A receptor availability and specify which brain networks were involved in healthy male subjects, using [ 18 F]altanserin positron emission tomography and resting-state functional magnetic resonance imaging. Behavioral inhibition system score negatively correlated with 5-HT 2A receptor availability in anterior cingulate cortex. A statistical model indicated that the behavioral inhibition system score was associated with 5-HT 2A receptor availability, which was mediated by the functional connectivity between anterior cingulate cortex and left middle frontal gyrus, both of which involved in the cognitive control of negative information processing. Individuals with high behavioral inhibition system displays low 5-HT 2A receptor availability in anterior cingulate cortex and this cognitive control network links with prefrontal-cingulate integrity. These findings have implications for underlying the serotonergic basis of physiologies in aversion.

Comment on “Relationship of Circulating Copper Level with Gestational Diabetes Mellitus: a Meta-analysis and Systemic Review” - Shu-ping Li; Xiao-ping Zhang; Xin-hong Cui; Li-juan Zhao; Yan-jun Rong (Biological Trace Element Research, 2022)

A Hybrid Neural Network Model for ENSO Prediction in Combination with Principal Oscillation Pattern Analyses - Lu Zhou; Rong-Hua Zhang (Advances in Atmospheric Sciences, 2022)

Structure and Evolution of Decadal Spiciness Variability in the North Pacific during 2004–20, Revealed from Argo Observations - Guanghui Zhou; Rong-Hua Zhang (Advances in Atmospheric Sciences, 2022)

Dynamic Cause of the Sudden Death Event of Small Yellow Croaker (Larimichthys polyactis) in the East China Sea in Winter 2017 - Zilu Wei; Xiaohui Jiao; Jicai Zhang; Yunfei Du; Zengrui Rong; Hui Wu; Ya Ping Wang (Frontiers in Marine Science, 2022)
Small yellow croaker ( Larimichthys polyactis ), a benthic fish species widely distributed in the Northwest Pacific Ocean, plays an important role in the fishery catch of coastal countries. A large amount of dead small yellow croaker floated on the sea surface near 30.2°N, 125.3°E in the East China Sea on 19 February 2017, and more than 9,000 kilograms were caught by fishermen, which had never been recorded before. This study aims to investigate the dynamic causes of this sudden death event based on available in-situ, satellite and modelling data. The event occurred near the overwintering ground of small yellow croaker, where a majority of these fish assembled in winter. There were persistent ocean fronts at target site with average intensity of 0.05°C/km at sea surface and bottom in February 2017, which was the strongest in the past 5 years from 2015 to 2019. The fronts provided nutrients and food to fish, and the intense gradients prevented fish from crossing, thus forming “water barriers” to restrict the horizontal movement of fish. Due to enhanced convection, the water was well-mixed, enabling the demersal croaker to float to sea surface. The sea temperature was particularly warm in winter 2017, but then experienced a significant drop by more than 4.5°C in 40 days according to satellite and modelling datasets due to the northerly wind and the southeastward movement of cold eddy. The drop of temperature led to ‘cold shock’ of fish, affecting their physiological regulation and survival. Under the combined influence of these factors, a large number of small yellow croaker died and aggregated near the target site. This paper has a great reference value for further study on the living habits of small yellow croaker and their responses to marine dynamic changes.

Phytoplankton Distributions in the Kuroshio-Oyashio Region of the Northwest Pacific Ocean: Implications for Marine Ecology and Carbon Cycle - Yaoyao Wang; Rong Bi; Jing Zhang; Jiawei Gao; Shigenobu Takeda; Yoshiko Kondo; Fajin Chen; Gui’e Jin; Julian P. Sachs; Meixun Zhao (Frontiers in Marine Science, 2022)
The Northwest Pacific Ocean (NWPO) is a significant sink for atmospheric CO 2 but a paucity of large-scale phytoplankton surveys in the upper and lower euphotic zone results in uncertainties in estimates of the efficiency of the biological carbon pump there. Here, we report the spatial distribution of lipid biomarkers from diatoms (brassicasterol/epi-brassicasterol), dinoflagellates (dinosterol), and haptophytes (C 37 alkenones) as proxies of phytoplankton biomass and community structure in suspended particles from the surface and deep chlorophyll maximum (DCM) layers across low- and mid-latitude regions of the NWPO. Our observations suggest that these lipid biomarkers can be used as indicators of the vertical distributions of phytoplankton biomass, which was comparable between the surface and DCM layers. Water masses with different nutrient concentrations strongly controlled the variations of lipid biomarkers, showing high biomass and the dominance of diatoms in the eutrophic Oyashio region, whereas low biomass and high proportions of dinoflagellates and haptophytes occurred in the oligotrophic Kuroshio region. Diatoms predominated in the DCM, likely enhancing carbon sequestration in the deep ocean and in sediments. Our results quantitatively demonstrate the horizontal and vertical variations of phytoplankton biomass and community structure, leading to an improved understanding of ecosystem function and biogeochemical cycles in this important region of the NWPO.

How do precipitation events modify the stable isotope ratios in leaf water at Lhasa on the southern Tibetan Plateau? - Yong Wang; Wusheng Yu; Lun Luo; Minghui Li; Xiaoming Liu; Rong Guo; Yaoming Ma; Baiqing Xu; Guangjan Wu; Chengyi Zhao; Zhaowei Jing; Feili Wei; et al. (Isotopes in Environmental and Health Studies, 2022)

Tumor Growth Inhibition-Overall Survival (TGI-OS) Model for Subgroup Analysis Based on Post-Randomization Factors: Application for Anti-drug Antibody (ADA) Subgroup Analysis of Atezolizumab in the IMpower150 Study - Kenta Yoshida; Phyllis Chan; Mathilde Marchand; Rong Zhang; Benjamin Wu; Marcus Ballinger; Nitzan Sternheim; Jin Y. Jin; René Bruno (The AAPS Journal, 2022)

Dominant species and evenness level co-regulate litter mixture decomposition in a boreal peatland - Xinhou Zhang; Yuanhang Zhang; Shuangshuang Jiang; Changchun Song; Jinbo Zhang; Rong Mao (Plant and Soil, 2022)

Ventromedial Thalamus-Projecting DCN Neurons Modulate Associative Sensorimotor Responses in Mice - Jie Zhang; Hao Chen; Li-Bin Zhang; Rong-Rong Li; Bin Wang; Qian-Hui Zhang; Liu-Xia Tong; Wei-Wei Zhang; Zhong-Xiang Yao; Bo Hu (Neuroscience Bulletin, 2022)

Identification and management of GCK-MODY complicating pregnancy in Chinese patients with gestational diabetes - Yanyan Jiang; Fusong Jiang; Ming Li; Qingkai Wu; Chenming Xu; Rong Zhang; Mingqiang Song; Yanzhong Wang; Ying Wang; Yating Chen; Juan Zhang; Xiaoxu Ge; et al. (Molecular and Cellular Biochemistry, 2022)

HucMSC-Ex alleviates inflammatory bowel disease via the lnc78583-mediated miR3202/HOXB13 pathway - Yuting Xu; Li Zhang; Dickson Kofi Wiredu Ocansey; Bo Wang; Yilin Hou; Rong Mei; Yongmin Yan; Xu Zhang; Zhaoyang Zhang; Fei Mao (Journal of Zhejiang University-SCIENCE B, 2022)

Analysis of Grain Yield Formation Components of Extra Heavy-Panicle-Type Mid-Season Indica Hybrid Rice - Xiaolong Zhong; Hafiz Athar Hussain; Bingbing Zhao; Manyu Huang; Saddam Hussain; Rong Xie; Linjun Cai; Han Yun; Guanghua He; Changwei Zhang (Journal of Plant Growth Regulation, 2022)

A low-cost in-situ CO2 sensor based on a membrane and NDIR for long-term measurement in seawater - Meng Li; Baolu Du; Jinjia Guo; Zhihao Zhang; Zeyu Lu; Rong’er Zheng (Journal of Oceanology and Limnology, 2022)

Correction to: Occurrence of Pestalotiopsis lushanensis causing leaf blight on Buddhist pine in China - Xiang-rong Zheng; Mao-jiao Zhang; Feng-mao Chen (European Journal of Plant Pathology, 2022)

Urinary phthalate metabolites in pregnant women: occurrences, related factors, and association with maternal hormones - Wei Wu; Zhi-li Ma; Fang Yang; Ping Wu; De-xin Zhang; Rong Zeng; Dan-ling Sun; Liu Cao (Environmental Science and Pollution Research, 2022)

Phytoremediation of uranium-contaminated soil by perennial ryegrass (Lolium perenne L.) enhanced with citric acid application - Lishan Rong; Shiqi Zhang; Jiali Wang; Shiyou Li; Shuibo Xie; Guohua Wang (Environmental Science and Pollution Research, 2022)

Quinolizidine alkaloids from the roots of Sophora flavescens - Jian-Chun Li; Zhi-Jun Zhang; Dan Liu; Ming-Yan Jiang; Rong-Tao Li; Hong-Mei Li (Natural Product Research, 2022)

Numerical Simulation and Test Investigation on Phase Transition and Thermal Cracking Process of Sandstone by Laser Drilling - Ke Chen; Zhiqiang Huang; Rong Deng; Wenlin Zhang; Minqiang Kang; Yachao Ma (Rock Mechanics and Rock Engineering, 2022)

The solar wind plasma upstream of Mars observed by Tianwen-1: Comparison with Mars Express and MAVEN - Kai Fan; Limei Yan; Yong Wei; Aibing Zhang; Linggao Kong; Markus Fränz; Fei He; Lihui Chai; Chongjing Yuan; Yuqi Wang; Jun Zhong; Zhaojin Rong; et al. (Science China Earth Sciences, 2022)

Involvement of Opioid Peptides in the Analgesic Effect of Spinal Cord Stimulation in a Rat Model of Neuropathic Pain - Fu-Jun Zhai; Song-Ping Han; Tian-Jia Song; Ran Huo; Xing-Yu Lan; Rong Zhang; Ji-Sheng Han (Neuroscience Bulletin, 2022)

Cassiterite oxygen isotopes in magmatic-hydrothermal systems: in situ microanalysis, fractionation factor, and applications - Yang Li; Sheng He; Rong-Qing Zhang; Xian-Wu Bi; Lian-Jun Feng; Guo-Qiang Tang; Wen-Zhong Wang; Fang Huang; Xian-Hua Li (Mineralium Deposita, 2022)

Sodium tanshinone IIA sulfonate improves cognitive impairment via regulating Aβ transportation in AD transgenic mouse model - Hui-Han Ma; Can Wan; Lu-Di Zhang; Rong-Rong Zhang; Dong Peng; Li-Jun Qiao; Shi-Jie Zhang; Ye-Feng Cai; Hong-Qiang Huang (Metabolic Brain Disease, 2022)

Effect of biochar on transformation of dissolved organic matter and DTPA-extractable Cu and Cd during sediment composting - Meihua Zhao; Caiyuan Cai; Zhen Yu; Hongwei Rong; Chaosheng Zhang; Shungui Zhou (Environmental Science and Pollution Research, 2022)

A historical record of trace metal deposition in northeastern Qinghai-Tibetan Plateau for the last two centuries - Shanying Li; Weiwei Sun; Rong Chen; Zhijie Zhang; Dongliang Ning; Zhenyu Ni (Environmental Science and Pollution Research, 2022)

Origin of Dispersed Organic Matter within Sandstones and Its Implication for Uranium Mineralization: A Case Study from Dongsheng Uranium Ore Filed in China - Fan Zhang; Yangquan Jiao; Shuangming Wang; Liqun Wu; Hui Rong (Journal of Earth Science, 2022)

Markers and Genetic Mechanisms of Primary and Epigenetic Oxidation of an Aeolian Depositional System of the Luohandong Formation, Ordos Basin - Yao Xiang; Yangquan Jiao; Liqun Wu; Hui Rong; Fan Zhang (Journal of Earth Science, 2022)

Novel blood-based hypomethylation of SH3BP5 is associated with very early-stage lung adenocarcinoma - Rong Qiao; Runbo Zhong; Chunlan Liu; Feifei Di; Zheng Zhang; Ling Wang; Tian Xu; Yue Wang; Liping Dai; Wanjian Gu; Baohui Han; Rongxi Yang (Genes & Genomics, 2022)

Neiella holothuriorum sp. nov., isolated from the gut of a sea cucumber Apostichopus japonicus - Xin-Feng Bai; Xue-Lian Lv; Xue Liu; Ting-Ting Cui; Mian-Song Zhang; Ning Ding; Chang-Heng Liu; Ai-Rong Jia (Antonie van Leeuwenhoek, 2022)

Reasonable application range of flocculation–solidification combined method in treatment of hydraulically dredged mud slurry - Rong-Jun Zhang; Zhi-Hao Xu; Jun-Jie Zheng; Lin-Wei Tu; Zhan-fang Huang (Marine Georesources & Geotechnology, 2022)

Experimental Study on Mechanical Properties of Highly Swelling Soft Rocks in the Yanji Basin, Northern China - Rong Zhao; Xiong Wu; Ge Zhu; Xiaolei Wang; Aoshuang Mei; Xiao Zhang (Rock Mechanics and Rock Engineering, 2022)

Functional characterization of tyrosine decarboxylase genes that contribute to acteoside biosynthesis in Rehmannia glutinosa - Yan Hui Yang; Mu Rong Yang; Jian Yu Zhu; Ke Wei Dong; Yan Jie Yi; Rui Fang Li; Lei Zeng; Chang Fu Zhang (Planta, 2022)

Pulsed exsolution of magmatic ore-forming fluids in tin-tungsten systems: a SIMS cassiterite oxygen isotope record - Yang Li; Rong-Qing Zhang; Sheng He; Massimo Chiaradia; Xian-Hua Li (Mineralium Deposita, 2022)

The establishment of giant panda (Ailuropoda melanoleuca) fibroblast cell line - Yuliang Liu; Jiasong Chen; Tongying Feng; Rong Hou; Zhigang Cai; Donghui Wang; Mingyue Zhang; Yuan Li; Yijiao Chen; Junhui An (In Vitro Cellular & Developmental Biology - Animal, 2022)

Occurrence of Pestalotiopsis lushanensis causing leaf blight on Buddhist pine in China - Xiang-rong Zheng; Mao-jiao Zhang; Feng-mao Chen (European Journal of Plant Pathology, 2022)

QTL mapping integrated with BSA-Seq analysis identifies a novel gene conferring resistance to brown planthopper from common wild rice (Oryza rufipogon Griff.) - Xuan Wang; Yue Han; Yue-xiong Zhang; Biao Deng; Bi-qiu Wu; Xin-ying Guo; Yu-fen Qin; Yao-yu Fang; Fang Liu; Bao-xiang Qin; Ji-jing Luo; Rong-bai Li (Euphytica, 2022)

Study on the impact of comprehensive urbanization on urban civil building CO2 emissions in China - Rong Guo; Nan Li; Hailin Mu; Ming Zhang; Xiyue Yang; Yixuan Han; Rongkang Yao; Zhihao Shao (Environmental Science and Pollution Research, 2022)

Effects of different photoperiods on flower opening, flower closing and circadian expression of clock-related genes in Iris domestica and I. dichotoma - Rong Liu; Yike Gao; Zhuping Fan; Chunjing Guan; Qixiang Zhang (Journal of Plant Research, 2022)

Quantifying interagency differences in intensity estimations of Super Typhoon Lekima (2019) - Lina Bai; Jie Tang; Rong Guo; Shuai Zhang; Kaiye Liu (Frontiers of Earth Science, 2022)

A New Species of Paradiplozoon (Monogenea: Diplozoidae), A Gill Parasite of the Schizothorax Fish (Cyprinidae: Schizothoracinae) from the Yarkand River, Xinjiang, China - Kadirden Arken; Cui-Lan Hao; Ai-Ming Guo; Wen-Run Zhang; Meng-Jie Rong; Wuljan Kamal; Sheng-Li Tian; Munira Kadir; Cheng Yue (Acta Parasitologica, 2022)

Sediment Resuspension as a Major Contributor to Sinking Particles in the Northwestern South China Sea: Evidence From Observations and Modeling - Lihua Ran; Wentao Ma; Martin G. Wiesner; Yuntao Wang; Jianfang Chen; Lanlan Zhang; Zhi Yang; Jingjing Zhang; Hongliang Li; Jian Ren; Rong Xiang; Erick Fredj (Frontiers in Marine Science, 2022)
The lateral advection of sinking particles is a well-known phenomenon in the South China Sea (SCS) and has a significant impact on the estimation of the efficiency of the biological carbon pump. However, little is known about the sources and pathways of sinking particles. Here, we present benthic and freshwater diatom fluxes and relative abundances collected by a sediment trap deployed at a water depth of 1,000 m and more than 500 m above the seafloor in the northwestern SCS, indicating that laterally transported resuspended sediment accounts for a significant part of the particle flux to the deep sea. A Lagrangian particle tracking model (LPTM) revealed that the resuspended particles likely originated from the neighboring continental slope, approximately 12–145 km to the west of the study site. Sediment trap observations and the LPTM together indicated that the impact of resuspended sediment occurred mainly in the deep water, and especially strong sediment resuspension was related to summer monsoon-induced coastal upwelling. The results suggest that particle resuspension has an important impact on the biological pump as well as on paleoenvironmental reconstructions of the SCS.

A new prenylated 3-benzoxepin derivative with anti-influenza A virus activity from Elsholtzia penduliflora - Lu Zhang; Linyao Yang; Rong-Tao Li; Fei Yu; Jindong Zhong (Natural Product Research, 2022)

Preparation and In Vitro Characterization of Gelatin Methacrylate for Corneal Tissue Engineering - Yayun Yan; Yanyan Cao; Rong Cheng; Zhizhong Shen; Yajing Zhao; Yixia Zhang; Guohong Zhou; Shengbo Sang (Tissue Engineering and Regenerative Medicine, 2022)

Non-vernalization requirement in Chinese kale caused by loss of BoFLC and low expressions of its paralogs - Qiwei Tang; Hanhui Kuang; Changchun Yu; Guanghui An; Rong Tao; Weiyi Zhang; Yue Jia (Theoretical and Applied Genetics, 2022)
Key message We identified the loss of BoFLC gene as the cause of non-vernalization requirement in B. oleracea . Our developed codominant marker of BoFLC gene can be used for breeding program of B. oleracea crops . Abstract Many species of the Brassicaceae family, including some Brassica crops, require vernalization to avoid pre-winter flowering. Vernalization is an unfavorable trait for Chinese kale ( Brassica oleracea var. chinensis Lei ), a stem vegetable, and therefore it has been lost during its domestication/breeding process. To reveal the genetics of vernalization variation, we constructed an F 2 population through crossing a Chinese kale (a non-vernalization crop) with a kale (a vernalization crop). Using bulked segregant analysis (BSA) and RNA-seq, we identified one major quantitative trait locus (QTL) controlling vernalization and fine-mapped it to a region spanning 80 kb. Synteny analysis and PCR-based sequencing results revealed that compared to that of the kale parent, the candidate region of the Chinese kale parent lost a 9,325-bp fragment containing FLC homolog ( BoFLC ). In addition to the BoFLC gene, there are four other FLC homologs in the genome of B. oleracea , including Bo3g005470 , Bo3g024250 , Bo9g173370, and Bo9g173400 . The qPCR analysis showed that the BoFLC had the highest expression among the five members of the FLC family. Considering the low expression levels of the four paralogs of BoFLC , we speculate that its paralogs cannot compensate the function of the lost BoFLC, therefore the presence/absence (PA) polymorphism of BoFLC determines the vernalization variation. Based on the PA polymorphism of BoFLC , we designed a codominant marker for the vernalization trait, which can be used for breeding programs of B. oleracea crops.

Activation of Autophagy Ameliorates Age-Related Neurogenesis Decline and Neurodysfunction in Adult Mice - Na Yang; Xueqin Liu; Xiaojie Niu; Xiaoqiang Wang; Rong Jiang; Na Yuan; Jianrong Wang; Chengwu Zhang; Kah-Leong Lim; Li Lu (Stem Cell Reviews and Reports, 2022)

Necrostatin-1 Relieves Learning and Memory Deficits in a Zebrafish Model of Alzheimer’s Disease Induced by Aluminum - Xiaocheng Gao; Ping Zhang; Jianping Chen; Lan Zhang; Nan Shang; Jin Chen; Rong Fan; Yanhong Wang; Tao Huang; Qiao Niu; Qinli Zhang (Neurotoxicity Research, 2022)

Upregulation of Striatal Metabotropic Glutamate Receptor Subtype 1 (mGluR1) in Rats with Excessive Glutamate Release Induced by N-Acetylcysteine - Tomoteru Yamasaki; Maki Okada; Atsuto Hiraishi; Wakana Mori; Yiding Zhang; Masayuki Fujinaga; Hidekatsu Wakizaka; Yusuke Kurihara; Nobuki Nengaki; Ming-Rong Zhang (Neurotoxicity Research, 2022)

Mass cultivation of conidia of Pyricularia oryzae - Zhong-na Hao; Hai-ping Qiu; Zhen Zhang; Rong-yao Chai; Shi-zhen Wang; Yan-li Wang; Jiao-yu Wang; Guo-chang Sun (Journal of Plant Pathology, 2022)

Transgelin-2 interacts with CD44 to regulate Notch1 signaling pathway and participates in colorectal cancer proliferation and migration - Rong Ding; Guoyu Li; Yueyi Yao; Lijuan Zhang; Xuan Zhang; Jiayi Li; Tao Shen; Yi Gao; Tao Wu; Shuzhen Kong; Ming Huang; Yunfeng Li (Journal of Physiology and Biochemistry, 2022)

Correction to: A native Trichoderma harzianum strain Th62 displays antagonistic activities against phytopathogenic fungi and promotes the growth of Celosia cristata - Xue-Yue Hou; Yue-Feng Wang; Chuan-Ying Jiang; Tong-Tong Zhai; Rui Miao; Jun-Jie Deng; Zhi-Hong Yao; Rong-Shu Zhang (Horticulture, Environment, and Biotechnology, 2022)

Understanding the key factors determining rural domestic waste treatment behavior in China: a meta-analysis - Donghui Zheng; Jing Shen; Rong Li; Bei Jian; Jihong Zeng; Yongliang Mao; Xiaoning Zhang; Pradipta Halder; Mei Qu (Environmental Science and Pollution Research, 2022)

Higher sequestration of wheat versus maize crop carbon in soils under rotations - Zheng-Rong Kan; Shou-Wei Han; Wen-Xuan Liu; Xin Zhao; Rattan Lal; Hai-Lin Zhang (Environmental Chemistry Letters, 2022)

An ocean modeling study to quantify wind forcing and oceanic mixing effects on the tropical North Pacific subsurface warm bias in CMIP and OMIP simulations - Yuchao Zhu; Rong-Hua Zhang; Delei Li (Climate Dynamics, 2022)

Association Between Essential Metal Elements and the Risk of Autism in Chinese Han Population - Jiahui Ma; Jing Wu; Haibin Li; Jingyu Wang; Jisheng Han; Rong Zhang (Biological Trace Element Research, 2022)

Selenium Deficiency Causes Inflammatory Injury in the Bursa of Fabricius of Broiler Chickens by Activating the Toll-like Receptor Signaling Pathway - Yu Bai; Ruili Zhang; Qing Liu; Rong Guo; Guangxing Li; Bin Sun; Di Zhang; Yang Chen; Xiaodan Huang (Biological Trace Element Research, 2022)

Overexpression of IbMPK3 increases low-temperature tolerance in transgenic sweetpotato - Rong Jin; Ho Soo Kim; Tao Yu; Ming Liu; Wenhui Yu; Peng Zhao; Aijun Zhang; Qiangqiang Zhang; Yaju Liu; Qinghe Cao; Sang-Soo Kwak; Zhonghou Tang (Plant Biotechnology Reports, 2022)

Epidemiological investigation and genetic characterization of porcine astrovirus genotypes 2 and 5 in Yunnan province, China - Keqing Ren; Rong Wang; Xiao Liu; Yinghua Liu; Jintao Zhang; Junyu Bi; Lianfeng Zhao; Zhigang Guo; Jianping Liu; Gefen Yin (Archives of Virology, 2022)

Human impacts alter driver–response relationships in lakes of Southwest China - Wenxiu Zheng; Enlou Zhang; Rong Wang; Peter Guy Langdon (Limnology and Oceanography, 2022)
Biodiversity and ecological stability are closely linked, and over recent timescales, anthropogenic impacts have accelerated losses in both from local to global scales. We attempt to show the combined response of diversity and stability of an aquatic community to changes in human activity as a driver. To address this, we measured the diversity and variability of chironomids and their drivers and nature of response to external conditions over the last century, based on 4 lake sediment sequences from Southwest China, one of world's 36 biodiversity hotspots. Our results showed that the driver–response relationship was linear in a lake without direct human impacts but nonlinear in human directly impacted lakes. Recent decreases in alpha diversity and increases in beta diversity were commonly recorded in all four lakes, suggesting that both species loss and a faster replacement of chironomid taxa are a regional phenomenon. However, in the same context of human‐induced global warming, increased variability and regime shifts only occurred in lowland lakes, directly disturbed by humans, highlighting that direct human impacts have overcome natural forcing as the determinant driver shaping the chironomid composition in these sites. In addition, we found that increases in beta diversity occurred prior to a regime shift and its character depends on how the community responds to the key external pressure. Our findings reveal that direct human disturbances have largely reshaped the chironomid composition and induced an earlier regime shift at the cost of species loss, resilience loss, and a change in driver–response type.

Mechanisms of soil organic carbon stability and its response to no‐till: A global synthesis and perspective - Zheng‐Rong Kan; Wen‐Xuan Liu; Wen‐Sheng Liu; Rattan Lal; Yash Pal Dang; Xin Zhao; Hai‐Lin Zhang (Global Change Biology, 2022)
Mechanisms of soil organic carbon (SOC) stabilization have been widely studied due to their relevance in the global carbon cycle. No‐till (NT) has been frequently adopted to sequester SOC; however, limited information is available regarding whether sequestered SOC will be stabilized for long term. Thus, we reviewed the mechanisms affecting SOC stability in NT systems, including the priming effects (PE), molecular structure of SOC, aggregate protection, association with soil minerals, microbial properties, and environmental effects. Although a more steady‐state molecular structure of SOC is observed in NT compared with conventional tillage (CT), SOC stability may depend more on physical and chemical protection. On average, NT improves macro‐aggregation by 32.7%, and lowers SOC mineralization in macro‐aggregates compared with CT. Chemical protection is also important due to the direct adsorption of organic molecules and the enhancement of aggregation by soil minerals. Higher microbial activity in NT could also produce binding agents to promote aggregation and the formation of metal‐oxidant organic complexes. Thus, microbial residues could be stabilized in soils over the long term through their attachment to mineral surfaces and entrapment of aggregates under NT. On average, NT reduces SOC mineralization by 18.8% and PE intensities after fresh carbon inputs by 21.0% compared with CT ( p Q 10 ) is observed in NT due to greater Q 10 in macro‐aggregates, an increase of soil moisture regime in NT could potentially constrain the improvement of Q 10 . This review improves process‐based understanding of the physical and chemical mechanism of protection that can act, independently or interactively, to enhance SOC preservation. It is concluded that SOC sequestered in NT systems is likely to be stabilized over the long term.

The Sources and Burial of Marine Organic Carbon in the Eastern China Marginal Seas - Yali Cao; Rong Bi; Xingchen Wang; Xi Chen; Jingwen Hu; Yaoyao Wang; Yiqing Jiang; Hailong Zhang; Lei Xing; Meixun Zhao (Frontiers in Marine Science, 2022)
The ecological functions and biogeochemical processes of continental marginal seas are important for the global carbon cycle. In the eastern China marginal seas (ECMS), phytoplankton productivity has increased significantly in recent decades, but the sources and burial processes of marine organic carbon (OC) remain under-studied. We analyzed the contents of marine lipid biomarkers (brassicasterol, dinosterol, and C 37 alkenones) in surface suspended particles obtained from seven cruises between 2010 and 2015, and in surface sediments from eight cruises between 2006 and 2012 in the ECMS, to estimate marine OC sources and burial. The correlations between lipid biomarkers and environmental factors were quantified to reveal controlling factors. The study area was divided into four regions according to cluster analysis conducted based on sediment parameters. Our results showed that the concentrations of marine lipid biomarkers in surface water were high near large estuaries such as the Changjiang River Estuary and the Yellow River Estuary, but those in surface sediments were high in mud areas. Nutrient concentration was a key factor controlling phytoplankton biomass in surface water, with high nutrients enhancing the growth of diatoms and dinoflagellates, while haptophytes were more abundant in low-nutrient, high-salinity and cold environments. High marine OC contents calculated from total OC δ 13 C were mainly associated with fine sediments transported by coastal currents, and finally deposited in mud areas. The proto-burial efficiency of marine OC in the ECMS (7–19%) was markedly higher than the mean value in global marginal seas, with high values being located in the western coast of the ECMS. The proto-burial efficiency of total marine lipid biomarkers (6–24%) was quantified for the first time in our study, with overall values and spatial patterns similar to that of marine OC. A key parameter for marine OC and marine biomarker proto-burial efficiency was sediment grain size. The smaller the sediment grain size was, the better the marine OC and marine biomarker were retained. Our study provides an important basis to elucidate spatial distribution patterns and forcing mechanisms of marine OC in surface water (production process) and surface sediments (burial process), and to estimate carbon budgets in large marginal seas.

The anticancer potential of the dietary polyphenol rutin: Current status, challenges, and perspectives - Arakkaveettil Kabeer Farha; Ren-You Gan; Hua-Bin Li; Ding-Tao Wu; Atanas G. Atanasov; Khalid Gul; Jia-Rong Zhang; Qiong-Qiong Yang; Harold Corke (Critical Reviews in Food Science and Nutrition, 2022)

Sampling Designs for Monitoring Ichthyoplankton in the Estuary Area: A Case Study on Coilia mystus in the Yangtze Estuary - Xiangyu Long; Rong Wan; Zengguang Li; Dong Wang; Pengbo Song; Fan Zhang (Frontiers in Marine Science, 2022)
A fishery-independent survey can provide detailed information for fishery assessment and management. However, the sampling design for the survey on ichthyoplankton in the estuary area is still poorly understood. In this study, we developed six stratified schemes with various sample sizes, attempting to find cost-efficient sampling designs for monitoring Coilia mystus ichthyoplankton in the Yangtze Estuary. The generalized additive model (GAM) with the Tweedie distribution was used to quantify the “true” distribution of C. mystus eggs and larvae, based on the data from the fishery-independent survey in 2019–2020. The performances of different sampling designs were evaluated by relative estimation error (REE), relative bias (RB), and coefficient of variation (CV). The results indicated that appropriate stratifications with intra-stratum homogeneity and inter-stratum heterogeneity could improve precision. The stratified schemes should be divided not only between the North Branch and South Branch but between river and sea. No less than two stratifications in the South Branch could also get better performance. The sample sizes of 45–55 were considered as the cost-efficient range. Compared to other monitoring programs, monitoring ichthyoplankton in the estuary area required a more complex stratification and a higher resolution sampling. The design ideology and optimization methodology in our study would provide references to sampling designs for ichthyoplankton in the estuary area.

Regulation of β1-integrin in autophagy and apoptosis of gastric epithelial cells infected with Helicobacter pylori - Boqing Li; Qianyu Rong; Yunqiu Du; Ruiqing Zhang; Jing Li; Xiaohan Tong; Li Geng; Ying Zhang (World Journal of Microbiology and Biotechnology, 2022)

Caffeine Inhibits Activation of the NLRP3 Inflammasome via Autophagy to Attenuate Microglia-Mediated Neuroinflammation in Experimental Autoimmune Encephalomyelitis - Hui-Qi Wang; Kai-Yi Song; Jin-Zhou Feng; Si-Yuan Huang; Xiu-Ming Guo; Lei Zhang; Gang Zhang; Ying-Chao Huo; Rong-Rong Zhang; Yue Ma; Qing-Zhe Hu; Xin-Yue Qin (Journal of Molecular Neuroscience, 2022)

Promotional effect of ZrO2 and WO3 on bimetallic Pt-Pd diesel oxidation catalyst - Rongrong Fan; Zhaoqiang Li; Yu Wang; Yan Wang; Zhiyong Ding; Cheng Zhang; Na Kang; Xin Guo; Rong Wang (Environmental Science and Pollution Research, 2022)

Soil nutrient variability mediates the effects of erosion on soil microbial communities: results from a modified topsoil removal method in an agricultural field in Yunnan plateau, China - Ruihuan Zhang; Li Rong; Lanlan Zhang (Environmental Science and Pollution Research, 2022)

Hydrogeochemistry, identification of hydrogeochemical evolution mechanisms, and assessment of groundwater quality in the southwestern Ordos Basin, China - Xiao Zhang; Rong Zhao; Xiong Wu; Wenping Mu (Environmental Science and Pollution Research, 2022)

Experimental study of vertical and batter pile groups in saturated sand using a centrifuge shaking table - Zhang Jian; Li Yurun; Yan Zhixiao; Huang Da; Rong Xian; Liang Yan (Earthquake Engineering and Engineering Vibration, 2022)

Infestation and distribution of mites on the Yunnan red-backed vole (Eothenomys miletus) in Yunnan Province of southwest China between 2001 and 2015 - Rong Xiang; Xian-Guo Guo; Tian-Guang Ren; Cheng-Fu Zhao; Rong Fan; Zhi-Wei Zhang; Ke-Yu Mao; Pei-Ying Peng; Xiao-Bin Huang; Ti-Jun Qian (Biologia, 2022)

Effect of water level on dynamic compaction in silty ground of Yellow River alluvial plain - Kai Yao; Yu Rong; Zhanyong Yao; Changyuan Shi; Chenjun Yang; Luchuan Chen; Baoshuo Zhang; Hongguang Jiang (Arabian Journal of Geosciences, 2022)

Circ_0002711 knockdown suppresses cell growth and aerobic glycolysis by modulating miR-1244/ROCK1 axis in ovarian cancer - Weiquan Xie; Lu Liu; Chuanyong He; Min Zhao; Rong Ni; Zixiong Zhang; Chengyu Shui (Journal of Biosciences, 2021)

Discovery of Genetic Biomarkers for Alzheimer’s Disease Using Adaptive Convolutional Neural Networks Ensemble and Genome-Wide Association Studies - An Zeng; Huabin Rong; Dan Pan; Longfei Jia; Yiqun Zhang; Fengyi Zhao; Shaoliang Peng (Interdisciplinary Sciences: Computational Life Sciences, 2021)

Examining the efficacy of revegetation practices in ecosystem restoration programs: insights from a hotspot of sandstorm in northern China - Ziqiang Du; Rong Rong; Zhitao Wu; Hong Zhang (Frontiers of Earth Science, 2021)

Three-dimensional numerical simulation of geothermal field in space—wavenumber domain - Dai Shi-Kun; Jia Jin-Rong; Qiang Jian-Ke; Chen Qing-Rui; Ling Jia-Xuan; Zhang Ying (Applied Geophysics, 2021)

Stress response mechanisms and description of three novel species Shewanella avicenniae sp. nov., Shewanella sedimentimangrovi sp. nov. and Shewanella yunxiaonensis sp. nov., isolated from mangrove ecosystem - Guo-Hong Liu; Qi Zhang; Manik Prabhu Narsing Rao; Shang Yang; Rong Tang; Huai Shi; Jie-Ping Wang; Guan-Min Huang; Bo Liu; Shun-Gui Zhou; Wen-Jun Li (Antonie van Leeuwenhoek, 2021)

On the Second-Year Warming in Late 2019 over the Tropical Pacific and Its Attribution to an Indian Ocean Dipole Event - Licheng Feng; Fei Liu; Rong-Hua Zhang; Xue Han; Bo Yu; Chuan Gao (Advances in Atmospheric Sciences, 2021)

Predictive value of monocyte to HDL cholesterol ratio for stroke-associated pneumonia in patients with acute ischemic stroke - Yaming Sun; Juan Lu; Danni Zheng; Jufen Qian; Hongxin Zhang; Dong Xing; Fengdan Rong; Yongjun Cao; Chun-Feng Liu; Shoujiang You (Acta Neurologica Belgica, 2021)

Application of Feature Point Matching Technology to Identify Images of Free-Swimming Tuna Schools in a Purse Seine Fishery - Qinglian Hou; Cheng Zhou; Rong Wan; Junbo Zhang; Feng Xue (Journal of Marine Science and Engineering, 2021)
Tuna fish school detection provides information on the fishing decisions of purse seine fleets. Here, we present a recognition system that included fish shoal image acquisition, point extraction, point matching, and data storage. Points are a crucial characteristic for images of free-swimming tuna schools, and point algorithm analysis and point matching were studied for their applications in fish shoal recognition. The feature points were obtained by using one of the best point algorithms (scale invariant feature transform, speeded up robust features, oriented fast and rotated brief). The k-nearest neighbors (KNN) algorithm uses ‘feature similarity’ to predict the values of new points, which means that new data points will be assigned a value based on how closely they match the points that exist in the database. Finally, we tested the model, and the experimental results show that the proposed method can accurately and effectively recognize tuna free-swimming schools.

Use of historical and contemporary distribution of mammals in China to inform conservation - Kang Huang; He Zhang; Chengliang Wang; Rong Hou; Pei Zhang; Gang He; Songtao Guo; Shiyi Tang; Baoguo Li; Charles Oxnard; Ruliang Pan (Conservation Biology, 2021)
A systematic understanding of dynamic animal extinction trajectories for different regions in a nation like China is critically important to developing practical conservation strategies. We explored historical and contemporary changes in terrestrial mammalian diversity to determine how diversity in each of the 5 regions in China has changed over time and to examine the conservation potential of these regions. We used records from databases on Pleistocene mammalian fossils and historical distribution records (1175–2020) for Primates (as a case study) to reconstruct evolutionary and historical distribution trajectories of the 11 orders of terrestrial mammals and to predict their prospective survival based on the national conservation strategy applied. The results indicated that since the Pleistocene, 4–5 mammalian orders have been lost in the northeast, 3 in central China, 2 along the coast, and 1 in the northwest. In the southwest, all 11 orders were maintained. Contemporarily, the coast and southwest had the highest and second‐highest species densities. The southwest region and southeastern sections of the northwest region were the most historically and contemporarily diverse areas, which suggests that they should be the first priority for protected area (PA) designation. The central and coastal areas should be secondarily prioritized. In these 2 regions, conservation should focus on human coexistence with nature. Less attention should be paid to the PA in the northeast and western northwest because in these areas ecosystems are depauperate and the climate is harsh. Conservation in these areas should focus principally on avoiding further human encroachment on natural areas. Article impact statement : Historical and contemporary patterns of extinction can be a basis for mammalian conservation strategies.

The Non-stationary Environmental Effects on Spawning Habitat of Fish in Estuaries: A Case Study of Coilia mystus in the Yangtze Estuary - Dong Wang; Rong Wan; Zengguang Li; Junbo Zhang; Xiangyu Long; Pengbo Song; Lu Zhai; Shuo Zhang (Frontiers in Marine Science, 2021)
The estuarine areas provide necessary spawning habitat, nursing habitat, and migratory for a variety of fishes and the environmental conditions are of significant heterogeneity. Coilia mystus is the key commercial fish that spawns in the Yangtze Estuary and the yield has declined sharply in the past 30 years. In order to understand the spawning habitat selection mechanism of C. mystus , the geographically weighted regression (GWR) model was applied to explore the non-stationary effect of environmental variables [e.g., the sea surface temperature (SST) and the sea surface salinity (SSS)] and geographical variables [e.g., the distance to the coast (DTC) and the depth (DEP) of water] on the egg density distribution of C. mystus . The data were derived from the spring and summer ichthyoplankton surveys carried out from 2019 to 2020 in the Yangtze Estuary, China. The GWR model results showed that the key variables in different seasons had spatial non-stationary effects on the distribution of spawning habitat of C. mystus , which were mainly caused by regional rise in temperature and saltwater intrusion of the South Branch. In the spring, the SSS, the DTC, and the DEP were the main impact factors and saltwater intrusion in the South Branch might lead to the trend that the spawning habitat moved further upstream to the Changxing Island. The SST was most important in the summer and the relatively lower SST was more crucial in the spawning habitat selection than the DTC and the DEP. The GWR model performed well in the study of C. mystus potential spawning habitat in the Yangtze Estuary. We recommend that more attention should be paid in regional variation of environmental factors to explore fish potential spawning habitat in the estuarine areas.

Differences in pathogenicity and physiologic races between Pyricularia oryzae isolates from indica and japonica rice varieties - Zhong-na Hao; Zhen Zhang; Hai-ping Qiu; Rong-yao Chai; Shi-zhen Wang; Yan-li Wang; Jiao-yu Wang; Guo-chang Sun (Journal of Plant Pathology, 2021)

Mortality risk attributable to diurnal temperature range: a multicity study in Yunnan of southwest China - Yujin Wang; Yang Chen; Jiaqi Chen; Rong Wu; Pi Guo; Shun Zha; Qingying Zhang (Environmental Science and Pollution Research, 2021)

Motor Circuit and Superior Temporal Sulcus Activities Linked to Individual Differences in Multisensory Speech Perception - Liyuan Li; Rong Li; Xinju Huang; Fei Shen; Hongyu Wang; Xuyang Wang; Chijun Deng; Chong Wang; Jiale Yang; Leiyao Zhang; Jiyi Li; Ting Zou; et al. (Brain Topography, 2021)

The effect of the PARK16 rs11240572 variant on brain structure in Parkinson's disease - Lu-yan Gu; Shao-bing Dai; Cheng Zhou; Ting Gao; Jing-jing Wu; Yi Fang; Xiao-jun Guan; Tao Guo; Ran Zheng; Chongyao Jin; Xiao-jun Xu; Zhe Song; et al. (Brain Structure and Function, 2021)

Lignans and phenylpropanoids from the liquid juice of phyllostachys edulis - De-Tao Wang; Ying-Ying Xue; Ying-Fang Zhang; Hang Xun; Qi-Rong Guo; Feng Tang; Jia Sun; Fei-Fei Qi (Natural Product Research, 2021)

Development and application of the Faba_bean_130K targeted next-generation sequencing SNP genotyping platform based on transcriptome sequencing - Chenyu Wang; Rong Liu; Yujiao Liu; Wanwei Hou; Xuejun Wang; Yamei Miao; Yuhua He; Yu Ma; Guan Li; Dong Wang; Yishan Ji; Hongyan Zhang; et al. (Theoretical and Applied Genetics, 2021)

Function identification of miR394 in tomato resistance to Phytophthora infestans - Yuan-Yuan Zhang; Yu-Hui Hong; Ya-Rong Liu; Jun Cui; Yu-Shi Luan (Plant Cell Reports, 2021)

CARMA1 is required for Notch1-induced NF-κB activation in SIL-TAL1-negative T cell acute lymphoblastic leukemia - Ninghan Zhang; Jiawen Xu; Rong Wang; Ting Pan; Huanxin Zhang; Lingling Yin; Yao Yao; Linyan Xu; Shengyun Zhu; Qingyun Wu; Zhenyu Li; Xuejiao Liu; et al. (Journal of Molecular Medicine, 2021)

Anti-miR33 therapy improved hepatopancreatic lipid and immune metabolism disorders in grass carp, Ctenopharyngodon idella - Rong-Hua Lu; Meng-Jun Lin; Feng Yang; Shen-zong Jia; Yu-Ru Zhang; Chao-Bin Qin; Xiao-Lin Meng; Guo-Xing Nie (Fish Physiology and Biochemistry, 2021)

Circular RNA circ_Cabin1 promotes DNA damage in multiple mouse organs via inhibition of non-homologous end-joining repair upon PM2.5 exposure - Huixian Zeng; Meizhen Li; Qiuhan Hua; Yufei Liu; Yueting Shao; Qinqin Diao; Yihui Ling; Han Zhang; Miaoyun Qiu; Jialu Zhu; Xun Li; Rong Zhang; et al. (Archives of Toxicology, 2021)

The effectiveness of extended binding affinity of prophage lysin PlyARI against Streptococcus suis infection - Yuyi Xiao; Rong Chen; Min Li; Zitai Qi; Yanfei Yu; Zihao Pan; Huochun Yao; Zhixin Feng; Wei Zhang (Archives of Microbiology, 2021)

Using AHP-VW model to evaluate the landslide susceptibility—a case study of Zigui County, Hubei Province, China - Zechen Zhang; Aiguo Zhou; Peng Huang; Rong Yang; Chuanming Ma (Arabian Journal of Geosciences, 2021)

A new atypical short‐chain dehydrogenase is required for interfungal combat and conidiation in Trichoderma guizhouense - Hong Zhu; Jian Zhang; Qi Gao; Guan Pang; Tingting Sun; Rong Li; Zhenzhong Yu; Qirong Shen (Environmental Microbiology, 2021)
Summary Hypocrealean Trichoderma are the most extensively studied facultative mycoparasites against phytopathogenic fungi. Aerial hyphae of Trichoderma guizhouense can rapidly proliferate over Fusarium oxysporum hyphae, cause sporadic cell death and arrest the growth of the host. The results of the present study demonstrated that a unique short‐chain dehydrogenase/reductase (SDR), designated as TgSDR1, was expressed at a high level in T . guizhouense challenged by the hosts. Similar to other SDRs family members, the TgSDR1 protein contains a cofactor‐binding motif and a catalytic site. The subcellular localization assay revealed that the TgSDR1::GFP fusion protein translocated to lipid droplets in mycelia and conidia. The data obtained using reverse genetic approach indicated that TgSDR1 is associated with antifungal ability, plays an important role in providing reducing equivalents in the form of NADPH and regulates the amino sugar and nucleotide sugar metabolism in T . guizhouense upon encountering a host. Moreover, the TgSDR1 deletion mutant was defective in conidiation. Thus, TgSDR1 functions as a key metabolic enzyme in T . guizhouense to regulate mycotrophic interactions, defence against other fungi, such as F . oxysporum , and conidiation.

Reduction of mussel metamorphosis by inactivation of the bacterial thioesterase gene via alteration of the fatty acid composition - Xiao-Meng Hu; Junbo Zhang; Wen-Yang Ding; Xiao Liang; Rong Wan; Sergey Dobretsov; Jin-Long Yang (Biofouling, 2021)

Seamount age prediction machine learning model based on multiple geophysical observables: methods and applications in the Pacific Ocean - Yongliang Bai; Yilin Rong; Jihong Sun; Leiming Chen; Diya Zhang; Zhengtong Yin (Marine Geophysical Research, 2021)

Toxicity of disinfection byproducts formed during the chlorination of sulfamethoxazole, norfloxacin, and 17β-estradiol in the presence of bromide - Yuanyuan Zhang; Yunjie Zhu; Yanan Shao; Chuan Rong; Zihan Pan; Jie Deng (Environmental Science and Pollution Research, 2021)

Influencing factors and physiochemical changes of embryogenesis through in vitro isolated microspore culture in Brassica species - Yan-Qi Dong; Yu-Hong Gao; Te Zhao; Guang-Qian Ren; Yan-Li Liu; Bin Guan; Rong-Xian Jin; Fei Gao; Yan-Li Zhang; Xiu-Fang Tan; Hong-Cai Zhu; Yu-Hong Zhang; et al. (Biologia, 2021)

Reconstruction method of irregular seismic data with adaptive thresholds based on different sparse transform bases - Hu Zhao; Tun Yang; Yu-Dong Ni; Xing-Gang Liu; Yin-Po Xu; Yi-Lei Zhang; Guang-Rong Zhang (Applied Geophysics, 2021)

Comparison of mitochondrial genomes provides insights into intron dynamics and evolution in Botryosphaeria dothidea and B . kuwatsukai - Bo Wang; Xiaofei Liang; Xiaojuan Hao; Haiyue Dang; Tom Hsiang; Mark L. Gleason; Rong Zhang; Guangyu Sun (Environmental Microbiology, 2021)
Summary Botryosphaeria dothidea is one of the most common fungal pathogens on a large number of hosts worldwide. Botryosphaeria dothidea and B. kuwatsukai are also the main causal agents of apple ring rot. In this study, we sequenced, assembled and annotated the circular mitogenomes of 12 diverse B . dothidea isolates (105.7–114.8 kb) infecting various plants including apple, and five diverse B . kuwatsukai isolates (118.0–124.6 kb) from apple. B . dothidea mitogenomes harboured a set of 29–31 introns and 48–52 ORFs. In contrast, B . kuwatsukai mitogenomes harboured more introns (32–34) and ORFs (51–54). The variation in mitogenome sizes was associated mainly with different numbers of introns and insertions of mobile genetic elements. Interestingly, B . dothidea and B . kuwatsukai displayed distinct intron distribution patterns, with three intron loci showing presence/absence dynamics in each species. Large numbers of introns (57% in B . dothidea and 49% in B . kuwatsukai ) were most likely obtained through horizontal transfer from non‐Dothideomycetes. The mitochondrial gene phylogeny supported the differentiation of the two species. Overall, this study sheds light into the mitochondrial evolution of the plant pathogens B . dothidea and B . kuwatsukai , and intron distribution patterns could be useful markers for studies on population diversity.

Biomechanical Strengthening Design for Limb Articulation Based on Reconstructed Skeleton Kinesthetics - Jing-Hua Xu; Zheng-Xin Tu; Jing-Xuan Xu; Shu-You Zhang; Jian-Rong Tan (Journal of Medical and Biological Engineering, 2021)

Enhanced Biodegradation of Hexachlorocyclohexane in Soil by Application of Exogenous Amendments - Xutong Liu; He Huang; Dan Huang; Kai Zhong; Qun Rong; Xingzi Qin; Chaolan Zhang; Xue Li (Water, Air, & Soil Pollution, 2021)

A stable QTL qSalt-A04-1 contributes to salt tolerance in the cotton seed germination stage - Qishen Gu; Huifeng Ke; Chenchen Liu; Xing Lv; Zhengwen Sun; Zhengwen Liu; Wei Rong; Jun Yang; Yan Zhang; Liqiang Wu; Guiyin Zhang; Xingfen Wang; et al. (Theoretical and Applied Genetics, 2021)

An inducible model for specific neutrophil depletion by diphtheria toxin in mice - Tianzhu Chao; Liaoxun Lu; Lichen Zhang; Rong Huang; Zhuangzhuang Liu; Binhui Zhou; Eryan Kong; Zhongjian Zhang; Toby Lawrence; Yinming Liang (Science China Life Sciences, 2021)

Sea surface salinity-derived indexes for distinguishing two types of El Niño events in the tropical Pacific - Hai Zhi; Pengfei Lin; Zhujun Fang; Hailong Liu; Rong-Hua Zhang; Wenrong Bai (Science China Earth Sciences, 2021)

Hippocampal Interneurons are Required for Trace Eyeblink Conditioning in Mice - Wei-Wei Zhang; Rong-Rong Li; Jie Zhang; Jie Yan; Qian-Hui Zhang; Zhi-An Hu; Bo Hu; Zhong-Xiang Yao; Hao Chen (Neuroscience Bulletin, 2021)
While the hippocampus has been implicated in supporting the association among time-separated events, the underlying cellular mechanisms have not been fully clarified. Here, we combined in vivo multi-channel recording and optogenetics to investigate the activity of hippocampal interneurons in freely-moving mice performing a trace eyeblink conditioning (tEBC) task. We found that the hippocampal interneurons exhibited conditioned stimulus (CS)-evoked sustained activity, which predicted the performance of conditioned eyeblink responses (CRs) in the early acquisition of the tEBC. Consistent with this, greater proportions of hippocampal pyramidal cells showed CS-evoked decreased activity in the early acquisition of the tEBC. Moreover, optogenetic suppression of the sustained activity in hippocampal interneurons severely impaired acquisition of the tEBC. In contrast, suppression of the sustained activity of hippocampal interneurons had no effect on the performance of well-learned CRs. Our findings highlight the role of hippocampal interneurons in the tEBC, and point to a potential cellular mechanism subserving associative learning.

Hydrated halloysite: the pesky stuff responsible for a cascade of landslides triggered by the 2018 Iburi earthquake, Japan - Fawu Wang; Shuai Zhang; Ran Li; Rong Zhou; Andreas Auer; Hiroto Ohira; Zili Dai; Tetsuya Inui (Landslides, 2021)

Evaluation of field resistance to brown stripe disease in novel and major cultivated sugarcane varieties in China - Xiao-Yan Wang; Xiao-Yan Cang; Wei Qin; Hong-Li Shan; Rong-Yue Zhang; Chang-Mi Wang; Wen-Feng Li; Ying-Kun Huang (Journal of Plant Pathology, 2021)

Effects of Mn2+ on neutral lipid content, C4 pathway, and related gene expression in Phaeodactylum tricornutum - Rong-Shi Chen; Li Zhang; Feng-Juan Wei; Lan-Ying Yuan; Pu Zhao; He-Yu Wang; Yi-Fu Gong (Journal of Applied Phycology, 2021)

Presence of microplastics in drinking water from freshwater sources: the investigation in Changsha, China - Maocai Shen; Zhuotong Zeng; Xiaofeng Wen; Xiaoya Ren; Guangming Zeng; Yaxin Zhang; Rong Xiao (Environmental Science and Pollution Research, 2021)

Exposure to antibiotics and mental disorders in children: a community-based cross-sectional study - Jingjing Zhang; Kaiyong Liu; Liang Sun; Linsheng Yang; Xinji Liu; Yitian Zhu; Rong Wei; Zhongxiu Jin; Li Wang; Ying Ma; Sufang Wang; Annuo Liu; et al. (Environmental Geochemistry and Health, 2021)

Colonization Characteristics of Poplar Fungal Disease Biocontrol Bacteria N6-34 and the Inhibitory Effect on Pathogenic Fungi by Real-Time Fluorescence Quantitative PCR Detection - Rong-bo Sa; Jun-li Zhang; Ji-zheng Sun; Yan-xia Gao (Current Microbiology, 2021)

A temperature-induced chitosanase bacterial cell-surface display system for the efficient production of chitooligosaccharides - Qianqian Li; Tuantuan Wang; Yangzhi Ye; Shimin Guan; Baoguo Cai; Shuo Zhang; Shaofeng Rong (Biotechnology Letters, 2021)

Effects of drought and heat on the productivity and photosynthetic characteristics of alpine meadow plants on the Qinghai-Tibetan Plateau - Li Ma; Zhong-hua Zhang; Bu-qing Yao; Zhen Ma; Xiao-tao Huang; Bing-rong Zhou; Man-hou Xu; Jing Guo; Hua-kun Zhou (Journal of Mountain Science, 2021)

Improvement on the Effectiveness of Marine Stock Enhancement in the Artificial Reef Area by a New Cage-Based Release Technique - Junbo Zhang; Yufeng He; Zhixing Guo; Shuheng Ji; Shuo Zhang; Yanli Tang; Huaxiang Sheng; Rong Wan; Daisuke Kitazawa (Journal of Ocean University of China, 2021)

Farnesoic acid methyltransferase 6 (BmFAMeT6) interrelates with moltinism of dominant trimolter in silkworm, Bombyx mori - Liang Zhang; Xiuzhi Li; Tian Li; Rong Xiong; Yan Li; Dongsheng Yan; Ping Chen (Biologia, 2021)

Oceanobacillus salinisoli sp. nov., a bacterium isolated from saline soil of Turpan city in Xinjiang province, north–west China - Wen-Yong Zhu; Li Yang; Zhou-Tian-Le Zhang; Chang-Gai Mu; Yun Wang; Ya-Rong Kou; Gang-Qiang Jiang; Min Yin; Shu-Kun Tang (Archives of Microbiology, 2021)

YAP promotes ocular neovascularization by modifying PFKFB3-driven endothelial glycolysis - Yifan Feng; Rong Zou; Xi Zhang; Minqian Shen; Xiuping Chen; Jing Wang; Weiran Niu; Yuanzhi Yuan; Fei Yuan (Angiogenesis, 2021)