Structure identification of a karst groundwater system based on high-resolution rainfall-hydrological response characteristics - Zongxing Wang; Rui Wu; Kun Huang; Yang Qiu; Zhongxia Li; You Lv; Junwei Wan (Environmental Science and Pollution Research, 2022)

Study on excavation stability of shallow rectangular shield pipe jacking tunnel - Wantao Ding; Zhongrong Wang; Xinghang Huang; Rui Chen; Lewen Zhang; Yingjie Zheng; Xiaowei Guo (Arabian Journal of Geosciences, 2022)

Face failure mechanism of shield tunnel in sandy ground with different low moisture contents - Zhongrong Wang; Wantao Ding; Xinghang Huang; Rui Chen; Keqi Liu (Arabian Journal of Geosciences, 2022)

Sulfoxaflor resistance in Aphis gossypii: resistance mechanism, feeding behavior and life history changes - Li Wang; Li Cui; Qinqin Wang; Yanpeng Chang; Weiling Huang; Changhui Rui (Journal of Pest Science, 2022)

Pseudonocardia humida sp. nov., an Actinomycete Isolated from Mangrove Soil Showing Distinct Distribution Pattern of Biosynthetic Gene Clusters - Zhen-Yu Zan; Xian-Feng Ge; Rui-Rui Huang; Wen-Zheng Liu (Current Microbiology, 2022)

The Antioxidant Role of Selenium via GPx1 and GPx4 in LPS-Induced Oxidative Stress in Bovine Endometrial Cells - Samson O. Adeniran; Peng Zheng; Rui Feng; Elikanah O. Adegoke; Fushuo Huang; Mingjun Ma; Ziming Wang; Olamigoke O. Ifarajimi; Xiaoyu Li; Guixue Zhang (Biological Trace Element Research, 2022)

Projected change in precipitation forms in the Chinese Tianshan Mountains based on the Back Propagation Neural Network Model - Rui Ren; Xue-mei Li; Zhen Li; Lan-hai Li; Yi-yu Huang (Journal of Mountain Science, 2022)

Trends of vegetation dynamics and its response to climate change in Pearl River Basin of southwestern China - Zhenfeng Wei; Yunyun Zheng; Rui Zhang; Lei Du; Qunying Huang; Shixin Yang (Arabian Journal of Geosciences, 2022)

Vision technique for deflection measurements based on laser positioning - Guojun Wang; Yaxin Huang; Qilin Zhao; Liang Chen; Ting Rui; Dongdong Zhang (European Journal of Environmental and Civil Engineering, 2022)

Isotope analysis reveals differential impacts of artificial and natural afforestation on soil organic carbon dynamics in abandoned farmland - Dong-Rui Di; Guang-Wei Huang (Plant and Soil, 2022)

Supply-chain impacts of Sichuan earthquake: a case study using disaster input–output analysis - Rui Huang; Arunima Malik; Manfred Lenzen; Yutong Jin; Yafei Wang; Futu Faturay; Zhiyi Zhu (Natural Hazards, 2022)

Secondary metabolites isolated from Agrimonia pilosa Ledeb. - Hong-Rui Li; Yu-Kui Li; Jian Xiao; Cui Yang; Meng-Yuan Jiang; Kai Tian; Wei Wang; Yan-Hong Li; Xiang-Zhong Huang (Natural Product Research, 2022)

Enhanced stripe rust resistance obtained by combining Yr30 with a widely dispersed, consistent QTL on chromosome arm 4BL - Shengjie Liu; Xiaoting Wang; Yayun Zhang; Yangang Jin; Zhonghua Xia; Mingjie Xiang; Shuo Huang; Linyi Qiao; Weijun Zheng; Qingdong Zeng; Qilin Wang; Rui Yu; et al. (Theoretical and Applied Genetics, 2022)

Organic-rich formation and hydrocarbon enrichment of lacustrine shale strata: A case study of Chang 7 Member - Quanyou Liu; Peng Li; Zhijun Jin; Yuewu Sun; Guang Hu; Dongya Zhu; Zhenkai Huang; Xinping Liang; Rui Zhang; Jiayi Liu (Science China Earth Sciences, 2022)

Correction to: Isorhamnetin protects against cardiac hypertrophy through blocking PI3K–AKT pathway - Lu Gao; Rui Yao; Yuzhou Liu; Zheng Wang; Zhen Huang; Binbin Du; Dianhong Zhang; Leiming Wu; Lili Xiao; Yanzhou Zhang (Molecular and Cellular Biochemistry, 2022)

Geochemical and Sr–Nd–Li isotopic constraints on the genesis of the Jiajika Li-rich pegmatites, eastern Tibetan Plateau: implications for Li mineralization - Hui Zhao; Bin Chen; Chao Huang; Chuang Bao; Qian Yang; Rui Cao (Contributions to Mineralogy and Petrology, 2022)

Functional variants of RPS6KB1 and PIK3R1 in the autophagy pathway genes and risk of bladder cancer - Lan Ma; Dongjian Zhang; Zhengkai Huang; Rui Zheng; Mulong Du; Qiang Lv; Chao Qin; Haiyan Chu; Lin Yuan; Zhengdong Zhang (Archives of Toxicology, 2022)

Sigma-1 Receptor Activation Suppresses Microglia M1 Polarization via Regulating Endoplasmic Reticulum–Mitochondria Contact and Mitochondrial Functions in Stress-Induced Hypertension Rats - Kokwin Ooi; Li Hu; Yi Feng; Chenzhi Han; Xiaorong Ren; Xinyi Qian; Haofeng Huang; Sijia Chen; Qi Shi; Hong Lin; Jijiang Wang; Danian Zhu; et al. (Molecular Neurobiology, 2021)

The transcribed ultraconserved element uc.51 promotes the proliferation and metastasis of breast cancer by stabilizing NONO - Xiaoqing Shi; Xiaofeng Huang; Rui Chen; Yan Li; Yinggang Xu; Weiwei Zhang; Qiannan Zhu; Xiaoming Zha; Jue Wang (Clinical & Experimental Metastasis, 2021)

Selenium-Alleviated Testicular Toxicity by Modulating Inflammation, Heat Shock Response, and Autophagy Under Oxidative Stress in Lead-Treated Chickens - Size Wang; Lulu Hou; Min Wang; Rui Feng; Xu Lin; Shifeng Pan; Qian Zhao; He Huang (Biological Trace Element Research, 2021)

Correction to: Temporal and spatial evolution patterns of drought in China over the past 500 years - Cuixia Wei; Bing Guo; Wenqian Zang; Fei Yang; Yuefeng Lu; Dafu Zhang; Hongwei Wu; Xiaoyan Zhen; Haorun Xue; Chao Meng; Shuting Chen; Xiao Yang; et al. (Arabian Journal of Geosciences, 2021)

cDNA cloning and expression analysis of glutaredoxin 3 in black tiger shrimp Penaeus monodon - Rui Fan; Yundong Li; Shigui Jiang; Song Jiang; Qibin Yang; Lishi Yang; Jianhua Huang; Falin Zhou (Aquaculture International, 2021)

Sedimentary Sequence, Evolution Model and Petroleum Geological Significance of Forced Regression: A Case Study of the Miocene Zhujiang Formation of the Pearl River Mouth Basin in the Northern South China Sea - Ye Yu; Linghui Cai; Changmin Zhang; Li Wang; Rui Zhu; Yanran Huang; Taotao Cao (Journal of Marine Science and Engineering, 2021)
Using 2D/3D seismic data and a large number of drilling and logging data and applying sequence stratigraphy, seismic sedimentology, and petroleum geology concepts, the characteristics of the sedimentary sequence of the forced regression have been analysed, the migration trajectory of the coastline have been reconstructed, the evolution model of the forced regression have been presented, and the significance for petroleum geology of the forced regressive sandbodies have been discussed. The falling stage systems tract (FSST) of the Zhujiang Formation present offlap high-angle oblique foreset reflection structure in the seismic profiles of the depositional trends and turbidite fan deposits with strong amplitude mound reflection structure are developed in the downdip direction of its front. The trajectory of migration of the shoreline shows a terraced downtrend in the direction of basin. The FSST is characterized by the shelf-edge delta without topset beds. The FSST was formed in the fall of relative sea-level. Five sets of foreset beds controlled by high-frequency relative eustatic were developed, therefore ordinal regressive overlap can be observed for the five sets of shelf-edge deltas in the depositional trends. The favourable reservoirs which were located close to the upper boundary of the falling stage systems tract and the basal surface of forced regression are sandbodies of the shelf-edge delta front and wave-dominated shoreface sands and the sandbodies of the turbidite fan. Those sandbodies favour the formation of lithologic oil–gas reservoirs by means of good trap sealing conditions, excellent oil–gas reserving performance, and effective oil source communication of fracture system.

Chemical constituents from the barks of Melia azedarach and their PTP1B inhibitory activity - Sheng-Nan Zhang; Lin Huang; Rui-Jing Ma; Mei-Feng Yang; Ben-Fu Wei; Hong-Zhi Song; Heng-Shan Wang; Qin-Gang Tan (Natural Product Research, 2021)

Comparative transcriptome analysis reveals that deletion of CheY influences gene expressions of ABC transports and metabolism in Haemophilus parasuis - Lvqin He; Xuefeng Yan; Ke Dai; Xintian Wen; Sanjie Cao; Xiaobo Huang; Rui Wu; Qin Zhao; Yong Huang; Qigui Yan; Xiaoping Ma; Xinfeng Han; et al. (Functional & Integrative Genomics, 2021)

Characteristics of ambient ammonia and its effects on particulate ammonium in winter of urban Beijing, China - Rui Zhang; Yuhua Han; Aijun Shi; Xuesong Sun; Xiao Yan; Yuhu Huang; Yu Wang (Environmental Science and Pollution Research, 2021)

Rhizosphere-associated nosZII microbial community of Phragmites australis and its influence on nitrous oxide emissions in two different regions - Rui Su; Rui Huang; Jin Zeng; Dayong Zhao; Rujia He; Zhongbo Yu; Qinglong L. Wu (Journal of Soils and Sediments, 2021)

Exploration of the developmental toxicity of TCS and PFOS to zebrafish embryos by whole-genome gene expression analyses - Guangzhu Dong; Rui Zhang; Hongyu Huang; Chuncheng Lu; Yankai Xia; Xinru Wang; Guizhen Du (Environmental Science and Pollution Research, 2021)

Genomic molecular signatures determined characterization of Mycolicibacterium gossypii sp. nov., a fast-growing mycobacterial species isolated from cotton field soil - Rui-Rui Huang; Shen-Rong Yang; Cheng Zhen; Xian-Feng Ge; Xin-Kai Chen; Zhi-Qiang Wen; Ya-Nan Li; Wen-Zheng Liu (Antonie van Leeuwenhoek, 2021)

Ectobacillus aegiceratis sp. nov., a novel bacterium isolated from branch of Aegiceras corniculatum - Xiao-Hui Chen; Xiao-Rui Yan; Zi-Hao Huang; Ming-Sheng Chen; Li Tuo (Antonie van Leeuwenhoek, 2021)

Jiella mangrovi sp. nov., a novel endophytic bacterium isolated from leaf of Rhizophora stylosa - Ming-Sheng Chen; Fei-Na Li; Xiao-Hui Chen; Zi-Hao Huang; Xiao-Rui Yan; Li Tuo (Antonie van Leeuwenhoek, 2021)

Overexpression of SoACLA-1 Gene Confers Drought Tolerance Improvement in Sugarcane - Kai Zhu; Chan Huang; Thi-Thu Phan; Li-Tao Yang; Bao-Qing Zhang; Yong-Xiu Xing; Yang-Rui Li (Plant Molecular Biology Reporter, 2021)

High-throughput sequencing reveals the spatial distribution variability of microbial community in coastal waters in Shenzhen - Rui Zhang; Yu Liu; Xianfeng Zhao; Zhihui Zhao; Honglian Zhang; Xiaoping Huang; Weiqing Xu; Yuchun Shen; Wensheng Lan (Ecotoxicology, 2021)

Biodegradation of Di-n-butyl phthalate in rhizosphere and growth-promoting effect of Cucumis sativus Linn. by a novel Pseudomonas sp. DNB-S1 - Shuqin Li; Lei Wang; Ying Li; Fuxin Huang; Hui Yu; Ying Zhang; Rui Li; Zhaobo Chen; Ningrui Wei; Zhengzhe Yu (Ecotoxicology, 2021)

Phycicoccus avicenniae sp. nov., a novel endophytic actinomycete isolated from a branch of Avicennia mariana - Ming-Sheng Chen; Xiao-Hui Chen; Zi-Hao Huang; Xiao-Rui Yan; Li Tuo (Antonie van Leeuwenhoek, 2021)

Elevated pCO2 Impedes Succession of Phytoplankton Community From Diatoms to Dinoflagellates Along With Increased Abundance of Viruses and Bacteria - Ruiping Huang; Jiazhen Sun; Yunlan Yang; Xiaowen Jiang; Zhen Wang; Xue Song; Tifeng Wang; Di Zhang; He Li; Xiangqi Yi; Shouchang Chen; Nanou Bao; et al. (Frontiers in Marine Science, 2021)
Eutrophic coastal regions are highly productive and greatly influenced by human activities. Primary production supporting the coastal ecosystems is supposed to be affected by progressive ocean acidification driven by increasing CO 2 emissions. In order to investigate the effects of high p CO 2 (HC) on eutrophic plankton community structure and ecological functions, we employed 9 mesocosms and carried out an experiment under ambient (∼410 ppmv) and future high (1000 ppmv) atmospheric p CO 2 conditions, using in situ plankton community in Wuyuan Bay, East China Sea. Our results showed that HC along with natural seawater temperature rise significantly boosted biomass of diatoms with decreased abundance of dinoflagellates in the late stage of the experiment, demonstrating that HC repressed the succession from diatoms to dinoflagellates, a phenomenon observed during algal blooms in the East China Sea. HC did not significantly influence the primary production or biogenic silica contents of the phytoplankton assemblages. However, the HC treatments increased the abundance of viruses and heterotrophic bacteria, reflecting a refueling of nutrients for phytoplankton growth from virus-mediated cell lysis and bacterial degradation of organic matters. Conclusively, our results suggest that increasing CO 2 concentrations can modulate plankton structure including the succession of phytoplankton community and the abundance of viruses and bacteria in eutrophic coastal waters, which may lead to altered biogeochemical cycles of carbon and nutrients.

Oxiracetam Mediates Neuroprotection Through the Regulation of Microglia Under Hypoxia-Ischemia Neonatal Brain Injury in Mice - Dan Wang; Yanbang Wei; Jingxia Tian; Dong He; Rui Zhang; Xiaoshuai Ji; Xiaoming Huang; Jun Sun; Jiajia Gao; Zixiao Wang; Qi Pang; Qian Liu (Molecular Neurobiology, 2021)

Refined mapping of stripe rust resistance gene YrP10090 within a desirable haplotype for wheat improvement on chromosome 6A - Shengjie Liu; Shuo Huang; Qingdong Zeng; Xiaoting Wang; Rui Yu; Qilin Wang; Ravi P. Singh; Sridhar Bhavani; Zhensheng Kang; Jianhui Wu; Dejun Han (Theoretical and Applied Genetics, 2021)

Improving rice eating and cooking quality by coordinated expression of the major starch synthesis-related genes, SSII and Wx, in endosperm - Lichun Huang; Zhengwen Gu; Zhuanzhuan Chen; Jiawen Yu; Rui Chu; Hongyan Tan; Dongsheng Zhao; Xiaolei Fan; Changquan Zhang; Qianfeng Li; Qiaoquan Liu (Plant Molecular Biology, 2021)

Long non-coding RNA NEAT1 promotes lipopolysaccharide-induced acute lung injury by regulating miR-424-5p/MAPK14 axis - Rui Zhang; Lina Chen; Fei Huang; Xiaorong Wang; Cuihong Li (Genes & Genomics, 2021)

The genomic content and context of auxiliary metabolic genes in roseophages - Xingyu Huang; Nianzhi Jiao; Rui Zhang (Environmental Microbiology, 2021)
Summary Marine bacteriophages frequently possess auxiliary metabolic genes (AMGs) that accelerate host metabolism during phage infection. The significance of AMGs in phage infecting the ecologically important Roseobacter clade, found predominantly in marine environments, remains to be determined. Here, we analysed the distribution and genomic context of 180 AMGs, annotated into 20 types, across 50 roseophage genomes. Roseophages share seven high‐frequency AMGs ( trx , grx , RNR, thyX , DCD, phoH , and mazG )， most of them involved in the nucleotide biosynthesis pathway that represent conserved intra and inter operational taxonomic units (OTUs), and share ≥97% full‐length DNA sequence similarity. Sporadic AMGs (dUTPase, lexA , degS , Que, NAPRT, AHL, pcnB , ctrA , RTX, RNR‐ nrdA , RNR‐ nrdE , wclP , and flgJ ), present in only one or two OTUs, show high functional diversity. The roseophage AMG repertoire weakly correlates with environmental factors, while host range partially explains the sporadic AMG distribution. Locally co‐linear blocks distribution index (LDI) analysis indicated that high‐frequency roseopodovirus AMGs are restricted to particular genomic islands, possibly originating from limited historical acquisition events. Low‐frequency roseopodovirus AMGs and all roseosiphovirus AMGs have high LDI values, implying multiple historical acquisition events. In summary, roseophages have acquired a range of AMGs through horizontal gene transfer, and the forces shaping the evolution of roseophages are described.

A new dineolignan with anti- β -amyloid aggregation activity from the fruits of crataegus pinnatifida bge - Peng Zhao; Li-Li Lou; Hao Zhang; Rui Guo; Xiao-Bo Wang; Xiao-Xiao Huang; Shao-Jiang Song (Natural Product Research, 2021)

Seismic active earth resistance of submerged backfill considering anisotropic seepage - Rui Huang; Nan Yang; Cong Cheng (Marine Georesources & Geotechnology, 2021)

Quantitative Proteomics Analysis of Sugarcane Ratoon Crop Chlorosis - Ye-Geng Fan; Rong-Fa Chen; Li-Hang Qiu; Zhong-Feng Zhou; Hui-Wen Zhou; Ji-Guang Wei; Xiu-Peng Song; Ting Luo; Prakash Lakshmanan; Xing Huang; Jian-Ming Wu; Yang-Rui Li (Sugar Tech, 2021)

DNA Methyltransferase 1 Is Dysregulated in Parkinson’s Disease via Mediation of miR-17 - Hong-Qiu Zhang; Jian-Yong Wang; Zhao-Feng Li; Lei Cui; Shi-Shi Huang; Lan-Bing Zhu; Yue Sun; Rui Yang; Hui-Hui Fan; Xiong Zhang; Jian-Hong Zhu (Molecular Neurobiology, 2021)

Analyzing and optimizing yield formation of tomato introgression lines using plant model - Mengzhen Kang; Xiujuan Wang; Rui Qi; Zhi-Qi Jia; Philippe de Reffye; San-Wen Huang (Euphytica, 2021)

Generation and identification of endothelial-specific Hrh2 knockout mice - Rui Meng; Wen-Ke Cai; Wen-Mang Xu; Qiang Feng; Ping Wang; Yan-hua Huang; Yu-Xin Fan; Tao Zhou; Qin Yang; Zhi-Ran Li; Gong-Hao He (Transgenic Research, 2021)

Composition and co-occurrence patterns of Phragmites australis rhizosphere bacterial community - Siwen Hu; Rujia He; Wanjie Wang; Dayong Zhao; Jin Zeng; Rui Huang; Ming Duan; Zhongbo Yu (Aquatic Ecology, 2021)

Contrasting pathways of carbon sequestration in paddy and upland soils - Xiangbi Chen; Yajun Hu; Yinhang Xia; Shengmeng Zheng; Chong Ma; Yichao Rui; Hongbo He; Daoyou Huang; Zhenhua Zhang; Tida Ge; Jinshui Wu; Georg Guggenberger; et al. (Global Change Biology, 2021)
Paddy soils make up the largest anthropogenic wetlands on earth, and are characterized by a prominent potential for organic carbon (C) sequestration. By quantifying the plant‐ and microbial‐derived C in soils across four climate zones, we identified that organic C accrual is achieved via contrasting pathways in paddy and upland soils. Paddies are 39%–127% more efficient in soil organic C (SOC) sequestration than their adjacent upland counterparts, with greater differences in warmer than cooler climates. Upland soils are more replenished by microbial‐derived C, whereas paddy soils are enriched with a greater proportion of plant‐derived C, because of the retarded microbial decomposition under anaerobic conditions induced by the flooding of paddies. Under both land‐use types, the maximal contribution of plant residues to SOC is at intermediate mean annual temperature (15–20°C), neutral soil (pH~7.3), and low clay/sand ratio. By contrast, high temperature (~24°C), low soil pH (~5), and large clay/sand ratio are favorable for strengthening the contribution of microbial necromass. The greater contribution of microbial necromass to SOC in waterlogged paddies in warmer climates is likely due to the fast anabolism from bacteria, whereas fungi are unlikely to be involved as they are aerobic. In the scenario of land‐use conversion from paddy to upland, a total of 504 Tg C may be lost as CO 2 from paddy soils (0–15 cm) solely in eastern China, with 90% released from the less protected plant‐derived C. Hence, preserving paddy systems and other anthropogenic wetlands and increasing their C storage through sustainable management are critical for maintaining global soil C stock and mitigating climate change.

A functional chromogen gene C from wild rice is involved in a different anthocyanin biosynthesis pathway in indica and japonica - Weihua Qiao; Yanyan Wang; Rui Xu; Ziyi Yang; Yan Sun; Long Su; Lizhen Zhang; Junrui Wang; Jingfen Huang; Xiaoming Zheng; Shijia Liu; Yunlu Tian; et al. (Theoretical and Applied Genetics, 2021)

Protective effect of Lycium barbarum polysaccharide on di-(2-ethylhexyl) phthalate-induced toxicity in rat liver - Rui-jing Liu; Yong-jian He; Huan Liu; Dong-dong Zheng; Shao-wen Huang; Chun-hong Liu (Environmental Science and Pollution Research, 2021)

Optimizing Protein-Glutaminase Expression in Bacillus subtilis - Xiaoying Ouyang; Yingjie Liu; Ruidan Qu; Min Tian; Ting Yang; Rui Zhu; Hongliang Gao; Mingfei Jin; Jing Huang (Current Microbiology, 2021)

Temporal and spatial evolution patterns of drought in China over the past 500 years - Cuixia Wei; Bing Guo; Wenqian Zang; Fei Yang; Yuefeng Lu; Dafu Zhang; Hongwei Wu; Xiaoyan Zhen; Haorun Xue; Chao Meng; Shuting Chen; Xiao Yang; et al. (Arabian Journal of Geosciences, 2021)

Rescue effects of Se-enriched rice on physiological and biochemical characteristics in cadmium poisoning mice - Yang Su; Ling Li; Muhammad Umer Farooq; Xin Huang; Tengda Zheng; Yu Jie Zhang; Hla Hla Ei; Faiz Hussain Panhwar; Zhichen Tang; Rui Zeng; Yuanke Liang; Xiaoying Ye; et al. (Environmental Science and Pollution Research, 2021)

Comparative Transcriptomic Analyses of Haemophilus parasuis Reveal Differently Expressed Genes among Strains with Different Virulence Degrees - Yuan Y. Zhou; Chao Wang; Jing Yuan; Rong L. Yin; Xin Chen; Rui Li; Xue L. Zhang; Jing Wang; Chen Huang; Rong H. Yin (Current Microbiology, 2021)

Association Between Blood Heavy Metal Concentrations and Dyslipidemia in the Elderly - Xingmeng Zhu; Yong Fan; Jie Sheng; Ling Gu; Qi Tao; Rui Huang; Kaiyong Liu; Linsheng Yang; Guimei Chen; Hongjuan Cao; Kaichun Li; Fangbiao Tao; et al. (Biological Trace Element Research, 2021)

Development of global soil erosion research at the watershed scale: a bibliometric analysis of the past decade - Xuan Huang; Kai-Rui Wang; Yu-wen Zou; Xin-Chun Cao (Environmental Science and Pollution Research, 2021)

Summertime atmosphere–sea ice coupling in the Arctic simulated by CMIP5/6 models: Importance of large-scale circulation - Rui Luo; Qinghua Ding; Zhiwei Wu; Ian Baxter; Mitchell Bushuk; Yiyi Huang; Xiquan Dong (Climate Dynamics, 2021)

Pseudomonas aeruginosa antitoxin HigA functions as a diverse regulatory factor by recognizing specific pseudopalindromic DNA motifs - Yingjie Song; Guihua Luo; Yibo Zhu; Tao Li; Changcheng Li; Lihui He; Ninglin Zhao; Chang Zhao; Jing Yang; Qin Huang; Xingyu Mu; Xinyue Tang; et al. (Environmental Microbiology, 2021)
Summary Type II toxin‐antitoxin (TA) systems modulate many essential cellular processes in prokaryotic organisms. Recent studies indicate certain type II antitoxins also transcriptionally regulate other genes, besides neutralizing toxin activity. Herein, we investigated the diverse transcriptional repression properties of type II TA antitoxin PaHigA from Pseudomonas aeruginosa . Biochemical and functional analyses showed that PaHigA recognized variable pseudopalindromic DNA sequences and repressed expression of multiple genes. Furthermore, we presented high resolution structures of apo‐PaHigA, PaHigA‐P higBA and PaHigA‐P pa2440 complex, describing how the rearrangements of the HTH domain accounted for the different DNA‐binding patterns among HigA homologues. Moreover, we demonstrated that the N‐terminal loop motion of PaHigA was associated with its apo and DNA‐bound states, reflecting a switch mechanism regulating HigA antitoxin function. Collectively, this work extends our understanding of how the PaHigB/HigA system regulates multiple metabolic pathways to balance the growth and stress response in P. aeruginosa and could guide further development of anti‐TA oriented strategies for pathogen treatment.

Small RNA Sequencing Analysis of Germinating Single-bud Seedcane Sett in Sugarcane - Kai-Chao Wu; Lin Xu; Zhi-Nian Deng; Tian Pang; Rong-Hua Zhang; Yi-Jie Li; Xiao-Yan Liu; Cheng-Feng Huang; Wen-Xian Qin; Jian-Feng Wei; Li-Ping Wei; Yang-Rui Li; et al. (Sugar Tech, 2021)

Seasonal variability and dynamics of coastal sea surface temperature fronts in the East China Sea - Lu Cao; Rui Tang; Wei Huang; Yuntao Wang (Ocean Dynamics, 2021)

The circular RNAs differential expression profiles in the metastasis of salivary adenoid cystic carcinoma cells - Rui Ju; Yanling Huang; Zeyou Guo; Lu Han; Suhui Ji; Luyang Zhao; Jie Long (Molecular and Cellular Biochemistry, 2021)

Characterization of TEMPO-oxidized chitin nanofibers with various oxidation times and its application as an enzyme immobilization support - Rui Chen; Wen-Can Huang; Wei Wang; Xiangzhao Mao (Marine Life Science & Technology, 2021)

CircRNA-23525 regulates osteogenic differentiation of adipose-derived mesenchymal stem cells via miR-30a-3p - Zeyou Guo; Luyang Zhao; Suhui Ji; Ting Long; Yanling Huang; Rui Ju; Wei Tang; Weidong Tian; Jie Long (Cell and Tissue Research, 2021)

Formaldehyde-induced hematopoietic stem and progenitor cell toxicity in mouse lung and nose - Yun Zhao; Laura C. Magaña; Haiyan Cui; Jiawei Huang; Cliona M. McHale; Xu Yang; Mark R. Looney; Rui Li; Luoping Zhang (Archives of Toxicology, 2021)

Cloning and expression analysis of hypoxia-related gene HO in cobia - Rui-tao Xie; Eric Amenyogbe; Wei-zheng Wang; Zhi-xiong Guo; Gang Chen; Jian-sheng Huang (Aquaculture International, 2021)

Seismic reflection evidence of crustal duplexing and lithospheric underthrusting beneath the western Qilian Mountains, northeastern margin of the Tibetan Plateau - Xingfu Huang; Rui Gao; Wenhui Li; Xiaosong Xiong (Science China Earth Sciences, 2021)

Effect of different industrial activities on soil heavy metal pollution, ecological risk, and health risk - Zhijie Long; Yi Huang; Wei Zhang; Zhangliang Shi; Daming Yu; Ying Chen; Chao Liu; Rui Wang (Environmental Monitoring and Assessment, 2021)

Numerical Study on Wave-Ice Interaction in the Marginal Ice Zone - Tiecheng Wu; Wanzhen Luo; Dapeng Jiang; Rui Deng; Shuo Huang (Journal of Marine Science and Engineering, 2020)
The effect of waves on ice sheet is critical in the marginal ice zone (MIZ). Waves break large sea ice into small pieces and cause them to collide with each other. Simultaneously, the interaction between sea ice and waves attenuates these waves. In this study, a numerical research is conducted based on a computational fluid dynamics (CFD) method to investigate the response of single ice floe to wave action. The obtained results demonstrate that the sea ice has a violent six degree of freedom (6DoF) motion in waves. Ice floes with different sizes, thicknesses, and shapes exhibit different 6DoF motions under the action of waves. The heave and surge response amplitude operator (RAO) of the sea ice are related to wavelength. Furthermore, the overwash phenomenon can be observed in the simulation. The obtained results are compared with the model test in the towing tank based on artificial ice, and they agree well with test results.

Three new andrastin derivatives from the endophytic fungus Penicillium vulpinum - Yu-Yue Qin; Xi-Shan Huang; Xiao-Bo Liu; Tu-Xiang Mo; Zhao-Long Xu; Ben-Chao Li; Xiao-Ya Qin; Jun Li; Till F. Schӓberle; Rui-Yun Yang (Natural Product Research, 2020)

Elevated plasma phage load as a marker for intestinal permeability in leukemic patients - Xue-rui Yin; Ping Liu; Xi Xu; Ying Xia; Kai-zhao Huang; Qiong-dan Wang; Mei-mei Lai; Qi-gui Yu; Xiao-qun Zheng (Medical Microbiology and Immunology, 2020)

Reducible Fraction Dominates the Mobility of Vanadium in Soil Around an Iron Smelter - Long Zhijie; Huang Yi; Zhang Wei; Shi Zhangliang; Yu Daming; Chen Yin; Liu Chao; Wang Rui (Bulletin of Environmental Contamination and Toxicology, 2020)

Stability assessment of tunnel slopes along the Dujiangyan City to Siguniang Mountain Railway, China - Junpeng Huang; Chunwei Sun; Xiyong Wu; Sixiang Ling; Sen Wang; Rui Deng (Bulletin of Engineering Geology and the Environment, 2020)

Structural variability and niche differentiation of the rhizosphere and endosphere fungal microbiome of Casuarina equisetifolia at different ages - Rui Huang; Pan Chen; Xuan Wang; Huimin Li; Linzhi Zuo; Yaqian Zhang; Lei Li (Brazilian Journal of Microbiology, 2020)

Non-thermal plasma-enhanced low-temperature catalytic desulfurization of electrolytic aluminum flue gas by CuO-ZrSnO4: experimental and numerical analysis - Zhiyuan Ning; Lianshuang Jiang; Zeyue Wang; Rui Huang; Zhenyu Zhang; Qiulin Zhang; Ping Ning (Environmental Science and Pollution Research, 2020)

The Forms, Distribution, and Risk Assessment of Sulfonamide Antibiotics in the Manure–Soil–Vegetable System of Feedlot Livestock - Caixia Jin; Shan Wei; Ruilian Sun; Wei Zou; Xingli Zhang; Qixing Zhou; Rui Liu; Liuqun Huang (Bulletin of Environmental Contamination and Toxicology, 2020)

Utilizing borehole electrical image and conventional logs to characterize petrology of mixed volcanic and sedimentary rocks in Jiamuhe Formation at JL2 Wellfield, Zhongguai Uplift, Junggar Basin, NW China - Rui Yuan; Lei Zhang; Qinghai Xu; Youlun Feng; Zhiyuan An; Jun Wu; Kang Zhao; Shuai Liu; Peng Huang (Arabian Journal of Geosciences, 2020)

High expression of long non-coding RNA Linc-A associates with poor survival in patients with colorectal cancer - Chong Zhao; Can Gan; Yang Xiao; Rui Liu; Linhao Zhang; Tian Lan; Yanting Ye; Huan Tong; Zhiyin Huang; Chengwei Tang; Jinhang Gao (Molecular Biology Reports, 2020)

Sulfur isotope and trace element compositions of pyrite determined by NanoSIMS and LA-ICP-MS: new constraints on the genesis of the Shuiyindong Carlin-like gold deposit in SW China - Jin-xiang Li; Rui-zhong Hu; Cheng-hai Zhao; Jing-jing Zhu; Yong Huang; Wei Gao; Jin-wei Li; Yu-zhou Zhuo (Mineralium Deposita, 2020)

CCL19 suppresses gastric cancer cell proliferation, migration, and invasion through the CCL19/CCR7/AIM2 pathway - Rui Zhou; Jun Sun; Chunping He; Chao Huang; Honggang Yu (Human Cell, 2020)

The abscisic acid receptor gene VvPYL4 positively regulates grapevine resistance to Plasmopara viticola - Li Liu; Chang-Yuan Liu; Hui Wang; Shu-Yi Yu; Tian-Shu Guan; Yu-Fei Huang; Rui-Chun Li (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)

Role of Chromatin Remodeling Genes and TETs in the Development of Human Midbrain Dopaminergic Neurons - Li Xiang; Guobin Huang; Wenjing Shu; Chunli Gong; Nan Cao; Rui Chen; Jixi Li; Hao Lu; Gaofeng Jiang (Stem Cell Reviews and Reports, 2020)

Ablation of olfactory bulb glutamatergic neurons induces depressive-like behaviors and sleep disturbances in mice - Mao-Yun Yuan; Ze-Ka Chen; Jian Ni; Tian-Xiao Wang; Shi-Yu Jiang; Hui Dong; Wei-Min Qu; Zhi-Li Huang; Rui-Xi Li (Psychopharmacology, 2020)

Reduction of heavy metals leaching and pore volume in high-volume fly ash cement pastes by adding nano-SiO2 - Qian Huang; Shuai Tang; Ya You; Yibo Chen; Haisen Deng; Rui Tian (Environmental Science and Pollution Research, 2020)

Late Early-Cretaceous Magma Mixing in the Langqi Island, Fujian Province, China: Evidences from Petrology, Geochemistry and Zircon Geochronology - Liangliang Huang; Liyuan Wang; Hong-Rui Fan; Musen Lin; Wenhui Zhang (Journal of Earth Science, 2020)

Utilizing borehole electrical images to evaluate sorting of conglomeratic formation: example from Lower Triassic Baikouquan Formation in Well M152, Mahu Depression, Junggar Basin, China - Rui Yuan; Bo Yang; Lingyu Huang; Wei Hu (Arabian Journal of Geosciences, 2020)

Anti-phytopathogenic Bacterial Metabolites From the Seaweed-Derived Fungus Aspergillus sp. D40 - Rui-Huan Huang; Wei Lin; Peng Zhang; Jian-Yang Liu; Dan Wang; Yi-Qiang Li; Xiao-Qiang Wang; Cheng-Sheng Zhang; Wei Li; Dong-Lin Zhao (Frontiers in Marine Science, 2020)

Long-term fertilization and intensive cropping enhance carbon and nitrogen accumulated in soil clay-sized particles of red soil in South China - Hu Xu; Kailou Liu; Wenju Zhang; Yichao Rui; Jingye Zhang; Lei Wu; Gilles Colinet; Qinghai Huang; Xianni Chen; Minggang Xu (Journal of Soils and Sediments, 2020)

Temporal variations in riverine hydrochemistry and estimation of the carbon sink produced by coupled carbonate weathering with aquatic photosynthesis on land: an example from the Xijiang River, a large subtropical karst-dominated river in China - Rui Yang; Hailong Sun; Bo Chen; Mingxing Yang; Qingrui Zeng; Cheng Zeng; Jie Huang; Huixian Luo; Danhui Lin (Environmental Science and Pollution Research, 2020)

Isolation of a novel strain Aspergillus niger WH-2 for production of l(+)-tartaric acid under acidic condition - Wenna Bao; Hongxiu Liao; Yi Chen; Qianqian Huang; Wendi Huang; Rui Fang; Shiwang Liu (Biotechnology Letters, 2020)

Integration of hepatitis B virus DNA into p21-activated kinase 3 (PAK3) gene in HepG2.2.15 cells - Peng Ruan; Xiufang Dai; Jun Sun; Chunping He; Chao Huang; Rui Zhou; Isabelle Chemin (Virus Genes, 2020)

Methane production from rice straw carbon in five different methanogenic rice soils: rates, quantities and microbial communities - Quan Yuan; Xiaozhen Huang; Junpeng Rui; Shaojun Qiu; Ralf Conrad (Acta Geochimica, 2020)

The stability and pressure behavior characteristics of a special L-type face end formed by low-pressure mining technology without pre-driving roadway - Ya-jun Wang; Jun Yang; Man-chao He; Rui-feng Huang; Xi-chun Tian; Jian-ning Liu; Hao-jie Xue (Arabian Journal of Geosciences, 2020)

Detection performance of azimuthal electromagnetic logging while drilling tool in anisotropic media - Zhen-Guan Wu; Lei Wang; Yi-Ren Fan; Shao-Gui Deng; Rui Huang; Tao Xing (Applied Geophysics, 2020)

Interaction between CA repeat microsatellites and HIF1α regulated the transcriptional activity of porcine IGF1 promoter - Hongwei Geng; Linlin Hao; Yunyun Cheng; Chunli Wang; Shan Huang; Wenzhen Wei; Rui Yang; Haoyang Li; Songcai Liu; Hao Yu; Huayi Lu (Journal of Applied Genetics, 2020)

Risk factors and clinical characteristics of tacrolimus-induced acute nephrotoxicity in children with nephrotic syndrome: a retrospective case-control study - Ping Gao; Xin-Lei Guan; Rui Huang; Xiao-Fang Shang-guan; Jiang-Wei Luan; Mao-Chang Liu; Hua Xu; Xiao-Wen Wang (European Journal of Clinical Pharmacology, 2020)

Mercury exposure in sedentary and migratory Charadrius plovers distributed widely across China - Tongping Su; Xin Lin; Qin Huang; Demeng Jiang; Chi Zhang; Xuecong Zhang; Caroline Dingle; Eben Goodale; Pinjia Que; Rui Wang; Yang Liu (Environmental Science and Pollution Research, 2020)

TNF-α suppresses sweat gland differentiation of MSCs by reducing FTO-mediated m6A-demethylation of Nanog mRNA - Yihui Wang; Rui Wang; Bin Yao; Tian Hu; Zhao Li; Yufan Liu; Xiaoli Cui; Liuhanghang Cheng; Wei Song; Sha Huang; Xiaobing Fu (Science China Life Sciences, 2020)

CD271 promotes STZ-induced diabetic wound healing and regulates epidermal stem cell survival in the presence of the pTrkA receptor - Min Zhang; Rui Zhang; Xiaohong Li; Yongqian Cao; Kaifeng Huang; Jun Ding; Mengyao Liu; Zhang Feng; Siyuan Yin; Jiaxu Ma; Huayu Zhang; Yibing Wang (Cell and Tissue Research, 2020)

Sediment microbiomes associated with the rhizosphere of emergent macrophytes in a shallow, subtropical lake - Rui Huang; Jin Zeng; Dayong Zhao; Katherine V. Cook; K. David Hambright; Zhongbo Yu (Limnology and Oceanography, 2020)
Rhizosphere microbiota has received much attention due to their associations with plant growth and their fundamental importance in terrestrial ecosystems. However, relatively few studies have focused on rhizosphere microbial communities associated with aquatic macrophytes in freshwater lakes. We hypothesized that the rhizosphere microbiome would reflect the presence of macrophyte roots and the concomitant microhabitat conditions the roots create. Here, high‐throughput sequencing and network analysis were employed to compare the composition and structure of bacterial communities in the rhizosphere of two common emergent macrophytes, Zizania latifolia and Phragmites australis , with the surrounding sediments in Lake Taihu (China). Results indicated that bacterial diversity, community composition, and co‐occurrence networks differed between the communities of bulk sediments and the communities of rhizosphere and surface sediments. Richness and phylogenetic diversity were higher and more taxa were enriched in the rhizosphere and surface sediment communities compared with bulk sediment communities. No differences were detected between bacterial communities in rhizosphere and surface sediments, nor between rhizospheres sediment communities of the two macrophyte species. Anaerobic taxa were more abundant in bulk sediment communities. Among the co‐occurrence networks, more nodes (operational taxonomic units) and edges (connections) with higher average degree as well as more topologically important nodes were found in rhizosphere and surface sediment communities relative to bulk communities. These findings suggest that rhizosphere microbiome communities are influenced by the presence of macrophyte roots, with oxygenated rhizosphere and surface sediment communities being more diverse, and organized into more interconnected co‐occurrence networks.

Effects of Exogenous GA3 and DPC Treatments on Levels of Endogenous Hormone and Expression of Key Gibberellin Biosynthesis Pathway Genes During Stem Elongation in Sugarcane - Li-Hang Qiu; Rong-Fa Chen; Han-Min Luo; Ye-Geng Fan; Xing Huang; Jun-Xian Liu; Fa-Qian Xiong; Hui-Wen Zhou; Chong-Kun Gan; Jian-Ming Wu; Yang-Rui Li (Sugar Tech, 2019)

Improvement and application research of the SRM in alpine regions - Gai-rui Hao; Jia-ke Li; Kang-bin Li; Kang Huang; Jia-bao Song; Huai-en Li (Environmental Science and Pollution Research, 2019)

U.S. national parks accessibility and visitation - Xing-ju Shen; Rui-hong Huang; Jin-shan Zhang (Journal of Mountain Science, 2019)

Yeast cell walls stimulate viability, respiratory burst, and phagocytosis in channel catfish (Ictalurus punctatus) head-kidney macrophages - Jianjun Zhou; Zhen Gao; Wenbiao Wang; Feng Huang; Junpeng Hu; Aqiong Gong; Rui Wang; Wumin Yang; Jie Li; Xianqin Hu; Xuedong Wang (Aquaculture International, 2019)

An improved method for detecting BeiDou signal-in-space anomalies from precise ephemerides - Lihong Fan; Rui Tu; Rui Zhang; Zengji Zheng; Xiaochun Lu; Jinhai Liu; Xiaodong Huang; Ju Hong (Acta Geodaetica et Geophysica, 2019)

Pathogenic mutations in two Chinese patients exhibiting severe early-onset obesity - Yanshan Liu; Wei Yang; Rui Hua; Yingzhi Huang; Xue Zhang (Science China Life Sciences, 2019)

Quality control of marine big data—a case study of real-time observation station data in Qingdao - Chengcheng Qian; Aichao Liu; Rui Huang; Qingrong Liu; Wenkun Xu; Shan Zhong; Le Yu (Journal of Oceanology and Limnology, 2019)

TGF-β Secretion by M2 Macrophages Induces Glial Scar Formation by Activating Astrocytes In Vitro - Gongyu Song; Rui Yang; Qian Zhang; Long Chen; Dujuan Huang; Junwei Zeng; Changpei Yang; Tao Zhang (Journal of Molecular Neuroscience, 2019)

Benefit–risk assessment of commonly consumed fish species from South China Sea based on methyl mercury and DHA - Ping Wang; Shao-wei Chen; Zi-hui Chen; Wei-lun Huo; Rui Huang; Wei-xiong Huang; Jie-wen Peng; Xing-fen Yang (Environmental Geochemistry and Health, 2019)

Two new sesquineolignans from the seeds of Crataegus pinnatifida and their β -amyloid aggregation inhibitory activitiy - Rui Guo; Le Zhou; Peng Zhao; Xiao-Bo Wang; Xiao-Xiao Huang; Shao-Jiang Song (Natural Product Research, 2019)

Molecular Cloning and Expression Analysis of ScTUA Gene in Sugarcane - Bao-Qing Zhang; Min Shao; Yong-Jian Liang; Xing Huang; Xiu-Peng Song; Hu Chen; Li-Tao Yang; Yang-Rui Li (Sugar Tech, 2019)

Uncommon Peptide Bond Cleavage of Glucagon from a Specific Vendor under near Neutral to Basic Conditions - Hong-Jian Zheng; Bin-Bin Shen; Jing Wang; Haibin Wang; Guo-Li Huo; Li-Rui Huang; Jian-Qing Gao; Wei-Jie Fang (Pharmaceutical Research, 2019)

A new coumarin from Juglans mandshurica Maxim induce apoptosis in hepatocarcinoma cells - Li-Li Lou; Peng Zhao; Zhuo-Yang Cheng; Rui Guo; Guo-Dong Yao; Xiao-Bo Wang; Xiao-Xiao Huang; Shao-Jiang Song (Natural Product Research, 2019)

Selection and validation of suitable reference genes for RT-qPCR analysis in dove tree (Davidia involucrata Baill.) - Rui Ren; Fengzhen Huang; Runxin Gao; Xujie Dong; Jiqing Peng; Fuxiang Cao; Meng Li (Trees, 2019)

The role of MAPK signaling pathway in formation of EMT in oral squamous carcinoma cells induced by TNF-α - Xiao-Wei Zhao; Jing-Ping Zhou; Yu-Lan Bi; Jia-Ying Wang; Rui Yu; Chao Deng; Wei-Kang Wang; Xian-Zhen Li; Rui Huang; Jili Zhang; De-Tao Tao (Molecular Biology Reports, 2019)

The origin of the carbonate-hosted Huize Zn–Pb–Ag deposit, Yunnan province, SW China: constraints from the trace element and sulfur isotopic compositions of pyrite - Yu-Miao Meng; Rui-Zhong Hu; Xiao-Wen Huang; Jian-Feng Gao; Christian Sasseville (Mineralogy and Petrology, 2019)

Extended STIRPAT model-based driving factor analysis of energy-related CO2 emissions in Kazakhstan - Chuanhe Xiong; Shuang Chen; Rui Huang (Environmental Science and Pollution Research, 2019)

Ethylene, xylene, toluene and hexane are major contributors of atmospheric ozone in Hangzhou, China, prior to the 2022 Asian Games - Rui Feng; Qing Wang; Cheng-chen Huang; Jin Liang; Kun Luo; Jian-ren Fan; Hui-jun Zheng (Environmental Chemistry Letters, 2019)

The roles of tropical and subtropical wind stress anomalies in the El Niño Modoki onset - Xin Wang; Chengyang Guan; Rui Xin Huang; Wei Tan; Lei Wang (Climate Dynamics, 2019)

A new method for evaluating the effectiveness of hydraulic fracturing in tight reservoirs - Fuping Feng; Rui Huang; Boyun Guo; Chi Ai; Chaoyang Hu; Yang Lei (Arabian Journal of Geosciences, 2019)

A high fidelity haze removal algorithm for optical satellite images using progressive transmission estimation based on the dark channel prior - Wei Huang; Yueyun Wang; Rui Wang (International Journal of Remote Sensing, 2019)

A miR-511-binding site SNP in the 3′UTR of IGF-1 gene is associated with proliferation and apoptosis of PK-15 cells - Wenzhen Wei; Gang Wang; Yunyun Cheng; Rui Yang; Jie Song; Shan Huang; Haoyang Li; Hongwei Geng; Hao Yu; Songcai Liu; Linlin Hao (In Vitro Cellular & Developmental Biology - Animal, 2019)

Winter chemical partitioning of metals bound to atmospheric fine particles in Dongguan, China, and its health risk assessment - Lin Huang; Yun-He Bai; Rui-Yue Ma; Ze-Ming Zhuo; Ling Chen (Environmental Science and Pollution Research, 2019)

Development of a colloidal gold-based immunochromatographic strip for rapid detection of Rice stripe virus - De-qing Huang; Rui Chen; Ya-qin Wang; Jian Hong; Xue-ping Zhou; Jian-xiang Wu (Journal of Zhejiang University-SCIENCE B, 2019)

An Innovative Sampling Method for Determining the Scale Effect of Rock Joints - Rui Yong; Ji-Bo Qin; Man Huang; Shi-Gui Du; Jie Liu; Gao-Jian Hu (Rock Mechanics and Rock Engineering, 2019)

QsvR integrates into quorum sensing circuit to control Vibrio parahaemolyticus virulence - Yiquan Zhang; Linghui Hu; Yue Qiu; George Osei‐Adjei; Hao Tang; Ying Zhang; Rui Zhang; Xiumei Sheng; Shungao Xu; Wenhui Yang; Huiying Yang; Zhe Yin; et al. (Environmental Microbiology, 2019)
Summary Vibrio parahaemolyticus , the leading cause of seafood‐associated gastroenteritis worldwide, requires the two type‐III secretion systems (T3SS1 and T3SS2) and a thermostable direct hemolysin (encoded by tdh1 and tdh2 ) for full virulence. The tdh genes and the T3SS2 gene cluster constitute an 80 kb pathogenicity island known as Vp‐PAI located on the chromosome II. Expression of T3SS1 and Vp‐PAI is regulated in a quorum sensing (QS)‐dependent manner but its detailed mechanisms remain unknown. Herein, we show that three factors (QS regulators AphA and OpaR and an AraC‐type transcriptional regulator QsvR) form a complex regulatory network to control the expression of T3SS1 and Vp‐PAI genes. At low cell density (LCD), whereas Vp‐PAI expression is repressed, T3SS1 genes are induced by AphA, which directly binds (an operator region of) the exsBAD‐vscBCD operon. At high cell density (HCD), the bacterium turns off T3SS1 expression by replacing AphA with OpaR, triggering the induction of Vp‐PAI. Furthermore, QsvR binds to the regulatory regions of all the tested T3SS1 and Vp‐PAI genes to activate their transcription at HCD. Taken together, our data highlight how multiple QS regulators contribute to the pathogenicity of V. parahaemolyticus by precisely controlling the expression of major virulence determinants during different stages of growth.

Molecular Cloning and Expressional Analysis of Five Sucrose Transporter (SUT) Genes in Sugarcane - Jun-Qi Niu; Jing-Li Huang; Thi-Thu Phan; Yong-Bao Pan; Li-Tao Yang; Yang-Rui Li (Sugar Tech, 2019)

Neonatal exposure to propofol affects interneuron development in the piriform cortex and causes neurobehavioral deficits in adult mice - Dan Yu; Rui Xiao; Jing Huang; Yulong Cai; Xiaohang Bao; Sheng Jing; Zhiyong Du; Tiande Yang; Xiaotang Fan (Psychopharmacology, 2019)

Modeling beach profile changes by typhoon impacts at Xiamen coast - Kai Yin; Sudong Xu; Wenrui Huang; Rui Li; Hong Xiao (Natural Hazards, 2019)

Development of polymorphic microsatellite loci for Ceratosolen gravelyi (Hymenoptera: Agaonidae), the pollinating wasp of Ficus semicordata (Urticales: Moraceae) - Li-Yuan Yang; Ai-Ying Wang; Zhu-Zeng Huang; Rui-Wu Wang; Da-Yong Zhang (Applied Entomology and Zoology, 2019)

Geostrophic Spirals Generated by the Horizontal Diffusion of Vortex Stretching in the Yellow Sea - Xiangzhou Song; Rui Xin Huang; Dexing Wu; Fangli Qiao; Guansuo Wang (Advances in Atmospheric Sciences, 2019)

Transcriptome Reveals Differentially Expressed Genes in Saccharum spontaneum GX83-10 Leaf Under Drought Stress - Kai-Chao Wu; Li-Ping Wei; Cheng-Mei Huang; Yuan-Wen Wei; Hui-Qing Cao; Lin Xu; Hai-Bin Luo; Sheng-Li Jiang; Zhi-Nian Deng; Yang-Rui Li (Sugar Tech, 2018)

Transgenic Rice Overexperessing a Tomato Mitochondrial Phosphate Transporter, SlMPT3;1, Promotes Phosphate Uptake and Increases Grain Yield - Guo-hong Yu; Sheng-cai Huang; Rui He; Ying-zhang Li; Xian-guo Cheng (Journal of Plant Biology, 2018)

Augmenter of liver regeneration promotes mitochondrial biogenesis in renal ischemia–reperfusion injury - Li-li Huang; Rui-ting Long; Gui-ping Jiang; Xiao Jiang; Hang Sun; Hui Guo; Xiao-hui Liao (Apoptosis, 2018)

Assessing spectral indices to estimate the fraction of photosynthetically active radiation absorbed by the vegetation canopy - Dailiang Peng; Helin Zhang; Le Yu; Mingquan Wu; Fumin Wang; Wenjiang Huang; Liangyun Liu; Rui Sun; Cunjun Li; Dacheng Wang; Fubao Xu (International Journal of Remote Sensing, 2018)

Carbon pools and fluxes in the China Seas and adjacent oceans - Nianzhi Jiao; Yantao Liang; Yongyu Zhang; Jihua Liu; Yao Zhang; Rui Zhang; Meixun Zhao; Minhan Dai; Weidong Zhai; Kunshan Gao; Jinming Song; Dongliang Yuan; et al. (Science China Earth Sciences, 2018)

Uptake of Urea Nitrogen by Oocystis borgei in Prawn (Litopenaeus vannamei) Aquaculture Ponds - Mei Liu; Xianghu Huang; Rui Zhang; Changling Li; Binhe Gu (Bulletin of Environmental Contamination and Toxicology, 2018)

Marine green alga Cladophora aokii Yamada and its epiphytes from Yinggehai, Hainan, China: morphological taxonomy, formation and analysis of its environmental adaption - Lanping Ding; Yue Dai; Bingxin Huang; Yongmei Li; Rui Liu; Shaoyang Deng (Acta Oceanologica Sinica, 2018)

An overview of the influence of atmospheric circulation on the climate in arid and semi-arid region of Central and East Asia - Yuzhi Liu; Chuqiao Wu; Rui Jia; Jianping Huang (Science China Earth Sciences, 2018)

Lappaconitine, a C18-diterpenoid alkaloid, exhibits antihypersensitivity in chronic pain through stimulation of spinal dynorphin A expression - Ming-Li Sun; Jun-Ping Ao; Yi-Rui Wang; Qian Huang; Teng-Fei Li; Xin-Yan Li; Yong-Xiang Wang (Psychopharmacology, 2018)

Use of cationic microbubbles targeted to P-selectin to improve ultrasound-mediated gene transfection of hVEGF165 to the ischemic myocardium - Wei-hui Shentu; Cao-xin Yan; Chun-mei Liu; Rui-xiang Qi; Yao Wang; Zhao-xu Huang; Li-ming Zhou; Xiang-dong You (Journal of Zhejiang University-SCIENCE B, 2018)

Health Risk Assessment for Local Residents from the South China Sea Based on Mercury Concentrations in Marine Fish - Shao-wei Chen; Zi-hui Chen; Ping Wang; Rui Huang; Wei-lun Huo; Wei-xiong Huang; Xing-fen Yang; Jie-wen Peng (Bulletin of Environmental Contamination and Toxicology, 2018)

Characterization of clinical features and outcome for human-to-human transmitted severe fever with thrombocytopenia syndrome - Bei Jia; Weihua Wu; Rui Huang; Guiyang Wang; Peixin Song; Yang Li; Yong Liu; Yali Xiong; Xiaomin Yan; Yingying Hao; Juan Xia; Zhaoping Zhang; et al. (Infectious Diseases, 2018)

Time is nothing: emotional consistency of autobiographical memory and its neural basis - Rui Xu; Juan Yang; Chunliang Feng; Haiyan Wu; Ruiwang Huang; Qiuli Yang; Zhihao Li; Pengfei Xu; Ruolei Gu; Yue-jia Luo (Brain Imaging and Behavior, 2018)

An adaptive sampling approach to reduce uncertainty in slope stability analysis - Jing-Sen Cai; Tian-Chyi Jim Yeh; E-Chuan Yan; Rui-Xuan Tang; Jet-Chau Wen; Shao-Yang Huang (Landslides, 2018)

Transformations of 2-line ferrihydrite and its effect on cadmium adsorption - Yi Huang; Shipeng Zhang; Chao Liu; Huilin Lu; Shijun Ni; Xin Cheng; Zhijie Long; Rui Wang (Environmental Science and Pollution Research, 2018)

Genomic changes in an attenuated genotype I Japanese encephalitis virus and comparison with virulent parental strain - Yuyong Zhou; Rui Wu; Yao Feng; Qin Zhao; Xintian Wen; Xiaobo Huang; Yiping Wen; Qigui Yan; Yong Huang; Xiaoping Ma; Xinfeng Han; Sanjie Cao (Virus Genes, 2018)

Estimation of the joint roughness coefficient (JRC) of rock joints by vector similarity measures - Rui Yong; Jun Ye; Qi-Feng Liang; Man Huang; Shi-Gui Du (Bulletin of Engineering Geology and the Environment, 2018)

Mutation of I176R in the E coding region weakens Japanese encephalitis virus neurovirulence, but not its growth rate in BHK-21 cells - Yuyong Zhou; Rui Wu; Qin Zhao; Yung-Fu Chang; Xintian Wen; Yao Feng; Xiaobo Huang; Yiping Wen; Qigui Yan; Yong Huang; Xiaoping Ma; Xinfeng Han; et al. (Archives of Virology, 2018)

Dietary exposure to cadmium of Shenzhen adult residents from a total diet study - Zhou Wang; Liubo Pan; Guihua Liu; Huimin Zhang; Jinzhou Zhang; Jie Jiang; Ying Xiao; Weibin Bai; Rui Jiao; Wei Huang (Food Additives & Contaminants: Part A, 2018)

Overexpression of Nogo receptor 3 (NgR3) correlates with poor prognosis and contributes to the migration of epithelial cells of nasopharyngeal carcinoma patients - Jiang-Yi He; Ping Han; Yu Zhang; Yong-Dong Liu; Shi-Jian Song; Guo-Kai Feng; Yu An; Ai-Jun Zhou; Hong-Bo Wang; Li Yuan; Zhi-Rui Lin; Tian-Liang Xia; et al. (Journal of Molecular Medicine, 2018)

Geochronology, geochemistry, and Sr–Nd–Pb–Hf isotopes of the Zhunsujihua granitoid intrusions associated with the molybdenum deposit, northern Inner Mongolia, China: implications for petrogenesis and tectonic setting - Xiaojun Zhang; David R. Lentz; Chunliang Yao; Rui Liu; Zhen Yang; Yanxiong Mei; Xianwang Fan; Fei Huang; Ying Qin; Kun Zhang; Zhenfei Zhang (International Journal of Earth Sciences, 2018)

Preparation of Fe-Cu-kaolinite for catalytic wet peroxide oxidation of 4-chlorophenol - Shiwei Zhou; Rui Xu; Jingzhe He; Yongchun Huang; Zejiang Cai; Minggang Xu; Zhengguo Song (Environmental Science and Pollution Research, 2018)

A single nucleotide mutation of IspF gene involved in the MEP pathway for isoprenoid biosynthesis causes yellow-green leaf phenotype in rice - Rui Huang; Yang Wang; Pingrong Wang; Chunmei Li; Fuliang Xiao; Nenggang Chen; Na Li; Caixia Li; Changhui Sun; Lihua Li; Rongjun Chen; Zhengjun Xu; et al. (Plant Molecular Biology, 2018)

Foliar application with nano-silicon reduced cadmium accumulation in grains by inhibiting cadmium translocation in rice plants - Rui Chen; Changbo Zhang; Yanling Zhao; Yongchun Huang; Zhongqi Liu (Environmental Science and Pollution Research, 2018)

Interaction between enterprises and consumers in a market of carbon-labeled products: a game theoretical analysis - Rui Zhao; Jiaojie Han; Shaozhuo Zhong; Ya Huang (Environmental Science and Pollution Research, 2018)

Effects of different C/N ratios on bacterial compositions and processes in an organically managed soil - Jun Ye; Pablo Gonzalez Perez; Rui Zhang; Shaun Nielsen; Danfeng Huang; Torsten Thomas (Biology and Fertility of Soils, 2018)

ThPP1 gene, encodes an inorganic pyrophosphatase in Thellungiella halophila, enhanced the tolerance of the transgenic rice to alkali stress - Rui He; Guohong Yu; Xiaori Han; Jiao Han; Wei Li; Bing Wang; Shengcai Huang; Xianguo Cheng (Plant Cell Reports, 2017)

Polyamine-binding protein PotD2 is required for stress tolerance and virulence in Actinobacillus pleuropneumoniae - Zhuang Zhu; Qin Zhao; Yu Zhao; Fei Zhang; Xintian Wen; Xiaobo Huang; Yiping Wen; Rui Wu; Qigui Yan; Yong Huang; Xiaoping Ma; Xinfeng Han; et al. (Antonie van Leeuwenhoek, 2017)

Regional disaster risk evaluation of China based on the universal risk model - Lu Chen; Yue-cheng Huang; Rui-zhen Bai; An Chen (Natural Hazards, 2017)

Creation of miniature pig model of human Waardenburg syndrome type 2A by ENU mutagenesis - Tang Hai; Weiwei Guo; Jing Yao; Chunwei Cao; Ailing Luo; Meng Qi; Xianlong Wang; Xiao Wang; Jiaojiao Huang; Ying Zhang; Hongyong Zhang; Dayu Wang; et al. (Human Genetics, 2017)

Thermal recovery process of a backfilled open-pit in permafrost area at the Gulian strip coal mine in Northeast China - Shu-hui Gao; Rui-xia He; Hui-jun Jin; Ya-dong Huang; Jian-ming Zhang; Dong-liang Luo (Journal of Mountain Science, 2017)

Detection and phylogenetic analysis of Mycoplasma hyopneumoniae from Tibetan pigs in western China - Gang Qiu; Yapei Rui; Kun Li; Shucheng Huang; Zhaoqing Han; Xiaoqiang Wang; Wenteng Jiang; Houqiang Luo; Yanfang Lan; Jiakui Li (Tropical Animal Health and Production, 2017)

Assessment of rhizosphere processes for removing water-borne macrolide antibiotics in constructed wetlands - Yiping Tai; Nora Fung-Yee Tam; Yunv Dai; Yang Yang; Jianhua Lin; Ran Tao; Yufen Yang; Jiaxi Wang; Rui Wang; Wenda Huang; Xiaodan Xu (Plant and Soil, 2017)

Inhibition of P2X7 Receptor Ameliorates Nuclear Factor-Kappa B Mediated Neuroinflammation Induced by Status Epilepticus in Rat Hippocampus - Cheng Huang; Xiao-sa Chi; Rui Li; Xin Hu; Hai-xia Xu; Jin-mei Li; Dong Zhou (Journal of Molecular Neuroscience, 2017)

Stocking density effects on growth and stress response of juvenile turbot (Scophthalmus maximus) reared in land-based recirculating aquaculture system - Baoliang Liu; Rui Jia; Kuifeng Zhao; Guowen Wang; Jilin Lei; Bin Huang (Acta Oceanologica Sinica, 2017)

Effects of Cd on reductive transformation of lepidocrocite by Shewanella oneidensis MR-1 - Chaolei Yuan; Fangbai Li; Rui Han; Tongxu Liu; Weimin Sun; Weilin Huang (Acta Geochimica, 2017)

Genome re-sequencing analysis uncovers pathogenecity-related genes undergoing positive selection in Magnaporthe oryzae - Jidong Cao; Yongqi Yu; Junkai Huang; Rui Liu; Yan Chen; Suiyan Li; Jun Liu (Science China Life Sciences, 2017)

Expression-based genotyping of the rice blast resistance genes in the elite maintainer line Yixiang1B - Li Wang; Xiao-Hong Hu; Gang Lin; De-Ming Zhao; Jun Shi; Zhi-Xue Zhao; Rui Zeng; Heng-Jing Li; De-Qiang Li; Jing Fan; Yan Li; Fu Huang; et al. (European Journal of Plant Pathology, 2017)

Enhanced dissipation of DEHP in soil and simultaneously reduced bioaccumulation of DEHP in vegetable using bioaugmentation with exogenous bacteria - Hai-Ming Zhao; Rui-Wen Hu; He-Biao Huang; Hong-Fei Wen; Huan Du; Yan-Wen Li; Hui Li; Quan-Ying Cai; Ce-Hui Mo; Jie-Sheng Liu; Ming-Hung Wong (Biology and Fertility of Soils, 2017)

Comparison of dust emissions, transport, and deposition between the Taklimakan Desert and Gobi Desert from 2007 to 2011 - SiYu Chen; JianPing Huang; JingXin Li; Rui Jia; NanXuan Jiang; LiTai Kang; XiaoJun Ma; TingTing Xie (Science China Earth Sciences, 2017)

The effect of Mg2+ on digestion performance and microbial community structures in sludge digestion systems - CongCong Liu; Cheng Huang; XiuYun Sun; Rui Li; Jiansheng Li; Jinyou Shen; Weiqing Han; Lianjun Wang (Environmental Science and Pollution Research, 2017)

A Shinella β-N-acetylglucosaminidase of glycoside hydrolase family 20 displays novel biochemical and molecular characteristics - Junpei Zhou; Zhifeng Song; Rui Zhang; Caihong Chen; Qian Wu; Junjun Li; Xianghua Tang; Bo Xu; Junmei Ding; Nanyu Han; Zunxi Huang (Extremophiles, 2017)

ATP-Citrate Lyase Gene (SoACLA-1), a Novel ACLA Gene in Sugarcane, and Its Overexpression Enhance Drought Tolerance of Transgenic Tobacco - Thi-Thu Phan; Jian Li; Bo Sun; Jia-Yi Liu; Wen-Hui Zhao; Chan Huang; Li-Tao Yang; Yang-Rui Li (Sugar Tech, 2017)

Isorhamnetin protects against cardiac hypertrophy through blocking PI3K–AKT pathway - Lu Gao; Rui Yao; Yuzhou Liu; Zheng Wang; Zhen Huang; Binbin Du; Dianhong Zhang; Leiming Wu; Lili Xiao; Yanzhou Zhang (Molecular and Cellular Biochemistry, 2017)

Cd Content in Sugarcane and Its Relationship with Soil Factors - Hui-Ping Ou; Liu-Qiang Zhou; Xi-Hui Liu; Jin-Sheng Huang; Yan Zeng; Ru-Lin Xie; Xiao-Hui Zhu; Hong-Wei Tan; Yang-Rui Li (Sugar Tech, 2017)

Role of the SPS Gene Families in the Regulation of Sucrose Accumulation in Sugarcane - Dong-Liang Huang; Cui-Xian Qin; Yi-Yun Gui; Li-Han Zhao; Zhong-Liang Chen; Miao Wang; Yue Sun; Qing Liao; Yang-Rui Li; Prakash Lakshmanan (Sugar Tech, 2017)

Effects of DDIT4 in Methamphetamine-Induced Autophagy and Apoptosis in Dopaminergic Neurons - Bing Li; Rui Chen; Ling Chen; Pingming Qiu; Xiuyun Ai; Enping Huang; Weiye Huang; Chuanxiang Chen; Chao Liu; Zhoumeng Lin; Wei-Bing Xie; Huijun Wang (Molecular Neurobiology, 2017)

Inhibition of mTOR Pathway by Rapamycin Decreases P-glycoprotein Expression and Spontaneous Seizures in Pharmacoresistant Epilepsy - Xiaosa Chi; Cheng Huang; Rui Li; Wei Wang; Mengqian Wu; Jinmei Li; Dong Zhou (Journal of Molecular Neuroscience, 2017)

Warming Effects on Ecosystem Carbon Fluxes Are Modulated by Plant Functional Types - Ji Chen; Yiqi Luo; Jianyang Xia; Kevin R. Wilcox; Junji Cao; Xuhui Zhou; Lifen Jiang; Shuli Niu; Katerina Y. Estera; Rujin Huang; Feng Wu; Tafeng Hu; et al. (Ecosystems, 2017)

Adenosine A2A receptors in the olfactory bulb suppress rapid eye movement sleep in rodents - Yi-Qun Wang; Rui Li; Dian-Ru Wang; Yoan Cherasse; Ze Zhang; Meng-Qi Zhang; Oriana Lavielle; Kristopher McEown; Serge N. Schiffmann; Alban de Kerchove d’Exaerde; Wei-Min Qu; Michael Lazarus; et al. (Brain Structure and Function, 2017)

Computation of satellite clock–ephemeris corrections using a priori knowledge for satellite-based augmentation system - Jie Chen; Zhigang Huang; Rui Li (GPS Solutions, 2017)

Genotoxicity and cytotoxicity reduction of the polluted urban river after ecological restoration: a field-scale study of Jialu River in northern China - Jie Sun; Rui Zhang; Long Qin; Haixiao Zhu; Yu Huang; Yingang Xue; Shuqing An; Xianchuan Xie; Aimin Li (Environmental Science and Pollution Research, 2017)

Evolution of a large intracranial artery dissection on multimodal neuroimaging with spontaneous healing - Qiao Zuo; Yi-bin Fang; Rui Zhao; Jian-min Liu; Qing-hai Huang (Acta Neurologica Belgica, 2017)

Isolation, chemical characterization, and immunomodulatory activity of naturally acetylated hemicelluloses from bamboo shavings - Ju-qing Huang; Rui-ting Qi; Mei-rong Pang; Cong Liu; Guang-yu Li; Ying Zhang (Journal of Zhejiang University-SCIENCE B, 2017)

Abnormal O-GlcNAcylation of Pax3 Occurring from Hyperglycemia-Induced Neural Tube Defects Is Ameliorated by Carnosine But Not Folic Acid in Chicken Embryos - Rui-Rong Tan; Yi-Fang Li; Shi-Jie Zhang; Wen-Shan Huang; Bun Tsoi; Dan Hu; Xin Wan; Xuesong Yang; Qi Wang; Hiroshi Kurihara; Rong-Rong He (Molecular Neurobiology, 2017)

Erratum to: Glycogen synthase kinase 3 (GSK3)-inhibitor SB216763 promotes the conversion of human umbilical cord mesenchymal stem cells into neural precursors in adherent culture - Liyang Gao; Mingyan Zhao; Peng Li; Junchao Kong; Zhijun Liu; Yonghua Chen; Rui Huang; Jiaqi Chu; Juanhua Quan; Rong Zeng (Human Cell, 2017)

Glycogen synthase kinase 3 (GSK3)-inhibitor SB216763 promotes the conversion of human umbilical cord mesenchymal stem cells into neural precursors in adherent culture - Liyang Gao; Mingyan Zhao; Peng Li; Junchao Kong; Zhijun Liu; Yonghua Chen; Rui Huang; Jiaqi Chu; Juanhua Quan; Rong Zeng (Human Cell, 2017)

Molecular cloning and characterization of α-amylase/subtilisin inhibitor from rhizome of Ligusticum chuanxiong - Ji-hua Yu; Yang-yang Li; Mian Xiang; Jian-quan Zhu; Xin-he Huang; Wan-Jun Wang; Rui Tan; Jia-yu Zhou; Hai Liao (Biotechnology Letters, 2017)

Frequency and type of inheritable mutations induced by γ rays in rice as revealed by whole genome sequencing - Shan Li; Yun-chao Zheng; Hai-rui Cui; Hao-wei Fu; Qing-yao Shu; Jian-zhong Huang (Journal of Zhejiang University-SCIENCE B, 2016)

MiR-28 inhibits cardiomyocyte survival through suppressing PDK1/Akt/mTOR signaling - Rui-Yao Zhu; Di Zhang; Han-Dong Zou; Xiao-Shu Zuo; Qing-Shan Zhou; He Huang (In Vitro Cellular & Developmental Biology - Animal, 2016)

A monotonically declining elevational pattern of bacterial diversity in freshwater lake sediments - Jin Zeng; Dayong Zhao; Huabing Li; Rui Huang; Jianjun Wang; Qinglong L. Wu (Environmental Microbiology, 2016)
Summary The distribution patterns of bacterial communities along elevational gradients remain unexplored in aquatic ecosystems. This study investigated the diversity and community composition of bacteria in the sediments of lakes along a mountainside elevational gradient from 525 to 4 490 m in western China. The bacterial alpha diversity (taxonomic richness and phylogenetic diversity) at different sediment depths decreased monotonically with the increasing elevation, and the beta diversity (dissimilarity between lakes) increased significantly with the increasing elevation distance. Both elevation and chemical variables including pH and carbon/nitrogen ratio were identified as major factors affecting the bacterial diversity. Especially, bacterial alpha/beta diversity was significantly related to both chemical and elevational gradients in the surface sediments, whereas elevation overwhelmed chemical factors in influencing the bacterial alpha/beta diversity in the subsurface sediments. Phylogenetic structure analysis demonstrated that environmental filtering was the most important process affecting the bacterial community assembly along the elevational gradient, and the strength of environmental filtering increased towards high elevations. In summary, we observed for the first time a monotonically decreasing elevational pattern in bacterial diversity of freshwater lake sediments, which is mainly driven by elevation associated environmental factors.

The destruction box is involved in the degradation of the NTE family proteins by the proteasome - Fei-Fei Huang; Ping-An Chang; Lan-Xi Sun; Wen-Zhen Qin; Li-Ping Han; Rui Chen (Molecular Biology Reports, 2016)

Metastasis associated genomic aberrations in stage II rectal cancer - Hong Zhao; Zhi-Zhou Shi; Rui Jiang; Dong-Bing Zhao; Hai-Tao Zhou; Jian-Wei Liang; Xin-Yu Bi; Jian-Jun Zhao; Zhi-Yu Li; Jian-Guo Zhou; Zhen Huang; Ye-Fan Zhang; et al. (Genes & Genomics, 2016)

Transcriptome of High-Sucrose Sugarcane Variety GT35 - Dong-Liang Huang; Yi-Jing Gao; Yi-Yun Gui; Zhong-Liang Chen; Cui-Xian Qin; Miao Wang; Qing Liao; Li-Tao Yang; Yang-Rui Li (Sugar Tech, 2016)

Tissue Transglutaminase and Its Product Isopeptide Are Increased in Alzheimer’s Disease and APPswe/PS1dE9 Double Transgenic Mice Brains - Ji Zhang; Suqing Wang; Wei Huang; David A. Bennett; Dennis W. Dickson; Dengshun Wang; Rui Wang (Molecular Neurobiology, 2016)

Celecoxib and octreotide synergistically ameliorate portal hypertension via inhibition of angiogenesis in cirrhotic rats - Jin-Hang Gao; Shi-Lei Wen; Shi Feng; Wen-Juan Yang; Yao-Yao Lu; Huan Tong; Rui Liu; Shi-Hang Tang; Zhi-Yin Huang; Ying-Mei Tang; Jin-Hui Yang; Hui-Qi Xie; et al. (Angiogenesis, 2016)
Abnormal angiogenesis is critical for portal hypertension in cirrhosis. Except for etiological treatment, no efficient medication or regime has been explored to treat the early stage of cirrhosis when angiogenesis is initiated or overwhelming. In this study, we explored an anti-angiogenesis effort through non-cytotoxic drugs octreotide and celecoxib to treat early stage of cirrhotic portal hypertension in an animal model. Peritoneal injection of thioacetamide (TAA) was employed to induce liver cirrhosis in rats. A combination treatment of celecoxib and octreotide was found to relieve liver fibrosis, portal venous pressure, micro-hepatic arterioportal fistulas, intrahepatic and splanchnic angiogenesis. Celecoxib and octreotide exerted their anti-angiogenesis effect via an axis of cyclooxygenase-2/prostaglandin E2/EP-2/somatostatin receptor-2, which consequently down-regulated phosphorylation of extracellular signal-regulated kinase (p-ERK)–hypoxia-inducible factor-1α (HIF-1α)–vascular endothelial growth factor (VEGF) integrated signaling pathways. In conclusions, combination of celecoxib and octreotide synergistically ameliorated liver fibrosis and portal hypertension of the cirrhotic rats induced by TAA via the inhibition of intrahepatic and extrahepatic angiogenesis. The potential mechanisms behind the regimen may due to the inactivation of p-ERK–HIF-1α–VEGF signaling pathway.

Molecular Design, Structural Analysis and Antifungal Activity of Derivatives of Peptide CGA-N46 - Rui-Fang Li; Zhi-Fang Lu; Ya-Nan Sun; Shi-Hua Chen; Yan-Jie Yi; Hui-Ru Zhang; Shuo-Ye Yang; Guang-Hai Yu; Liang Huang; Chao-Nan Li (Interdisciplinary Sciences: Computational Life Sciences, 2016)

Optimization of the Expression Conditions of CGA-N46 in Bacillus subtilis DB1342(p-3N46) by Response Surface Methodology - Rui-Fang Li; Bin Wang; Shuai Liu; Shi-Hua Chen; Guang-Hai Yu; Shuo-Ye Yang; Liang Huang; Yan-Li Yin; Zhi-Fang Lu (Interdisciplinary Sciences: Computational Life Sciences, 2016)

Application of TiO2-organobentonite modified by cetyltrimethylammonium chloride photocatalyst and polyaluminum chloride coagulant for pretreatment of aging landfill leachate - Yi-Jie Zhang; Zhao-Hui Yang; Pei-Pei Song; Hai-Yin Xu; Rui Xu; Jing Huang; Juan Li; Yan Zhou (Environmental Science and Pollution Research, 2016)