Immunotherapies for the Effective Treatment of Primary Autoimmune Cerebellar Ataxia: a Case Series - Jiao Li; Bo Deng; Wenli Song; Keru Li; Jingwen Ai; Xiaoni Liu; Haocheng Zhang; Yi Zhang; Ke Lin; Guofu Shao; Chunfeng Liu; Wenhong Zhang; et al. (The Cerebellum, 2022)

Two new phenylpropenoid glycosides from the roots of Illicium dunnianum - Yi-lin Wang; Han Li; Ling Song; Yun-hang Gao; Teng-fei Chen (Natural Product Research, 2022)

Two new sesquiterpenoid lactone derivatives from Lindera aggregata - Song-Song Wen; Yan Wang; Jia-Ping Xu; Qi Liu; Lei Zhang; Jing Zheng; Lin Li; Na Zhang; Xin Liu; Yu-Wen Xu; Zhen-Liang Sun (Natural Product Research, 2022)

7,8-Dihydroxyflavone attenuates the virulence of Staphylococcus aureus by inhibiting alpha-hemolysin - Nan Bian; Xiangqian Chen; Xinran Ren; Zishu Yu; Mengli Jin; Xiaoyu Chen; Chang Liu; Yanhe Luan; Lin Wei; Ying Chen; Wu Song; Yicheng Zhao; et al. (World Journal of Microbiology and Biotechnology, 2022)

A 10-miRNA risk score-based prediction model for pathological complete response to neoadjuvant chemotherapy in hormone receptor-positive breast cancer - Chang Gong; Ziliang Cheng; Yaping Yang; Jun Shen; Yingying Zhu; Li Ling; Wanyi Lin; Zhigang Yu; Zhihua Li; Weige Tan; Chushan Zheng; Wenbo Zheng; et al. (Science China Life Sciences, 2022)

Synthesis and biological evaluation of new thiazolyl-urea derivatives as potential dual C-RAF/FLT3 inhibitors - Zhi-Hua Zhang; Bi-Fan Zeng; Zhe-Xue Song; Ying-Yu Yang; Kai-yun Zhang; Xue Du; Lin-lin Zhang; Dong Cai (Medicinal Chemistry Research, 2022)

Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice - Bo Yang; Zhan Gao; Qi-Shuang Li; Xiang-Ye Zhang; Lan Song; Yi-Ni Wang; Xin-Yue Wang; Lin-Lin Ji; Hong-Liang Xu; Hui Xie; Fu-Kai Feng; Xiao-Ping Li; et al. (Inflammation Research, 2022)

Comprehensive comparison of the prognostic value of systemic inflammation biomarkers for cancer cachexia: a multicenter prospective study - Hailun Xie; Guotian Ruan; Lishuang Wei; Heyang Zhang; Yizhong Ge; Qi Zhang; Shiqi Lin; Mengmeng Song; Xi Zhang; Xiaoyue Liu; Ming Yang; Meng Tang; et al. (Inflammation Research, 2022)

Incineration disposal of organic waste bio-residue via a deep dewatering process using refuse incineration bottom ash: moisture transfer and low calorific value improvement - Ran Wei; Ruina Zhang; Lijie Song; Xiong Zhou; Shunhong Lin; Youcai Zhao; Tao Zhou (Environmental Science and Pollution Research, 2022)

A new numerical model of ring shear tester for shear band soil considering friction-induced thermal pressurization - Neng-hao Zhao; Kun Song; Rong-tang Zhang; Qing-lin Yi (Journal of Mountain Science, 2022)

Research on the Enhancement of the Separation Efficiency for Discrete Phases Based on Mini Hydrocyclone - Lin Liu; Lixin Zhao; Yahong Wang; Shuang Zhang; Minhang Song; Xueqiang Huang; Zhongrun Lu (Journal of Marine Science and Engineering, 2022)
The economic and efficient treatment of mixed media in offshore produced fluids is of great significance to oilfield production. Due to the small space and limited load-bearing capacity of offshore platforms, some mature multiphase media separation processes in onshore oilfields are difficult to apply. Therefore, high-efficiency processing methods with small-occupied space are required. Mini hydrocyclones (MHCs) are a potential separation method due to their simple structure, small footprint, and high separation efficiency (especially for fine particles or droplets). However, for discrete phases with different densities and sizes, the enhancement rule of the separation efficiency of MHCs is not yet clear. In this paper, numerical simulation methods were used to study the separation performance of hydrocyclones with different main diameters (including conventional hydrocyclones (CHCs) and MHCs) for discrete phases with different densities and particle sizes. Results show that MHC has the optimal enhancement range for oil–water separation when oil-droplet sizes are 60–300 μm, while the optimal enhancement range for silica particle and water separation is 10–40 μm. For other droplet/particle size ranges, the efficiency enhancement effect of MHC is not obvious compared to conventional hydrocyclones. By calculating the radial force of particles in MHC and CHC, the reasons for the enhanced efficiency of MHC are theoretically analyzed. The pressure drop of MHC is higher than CHC under the same feed velocity, which can be improved by connecting CHC with MHC. Additionally, the fluid velocity test experiments based on particle image velocimetry (PIV) were carried out to verify the accuracy of the numerical simulations. This study clarified the scope of application of MHCs to different discrete phase types, in order to provide a basis for the precise application of MHCs.

Associations of metal profiles in blood with thyroiditis: a cross-sectional study - Yaosheng Luo; Huixian Zeng; Yanshi Ye; Genfeng Yu; Cheng Song; Siyang Liu; Xingying Chen; Yuqi Jiang; Hualin Duan; Yue Li; Shengqing He; Zhi Chen; et al. (Environmental Science and Pollution Research, 2022)
Autoimmune thyroiditis (AIT) is increasingly common, and serological markers include thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TgAb). To determine if selected metals influence thyroiditis antibody positivity, this cross-sectional study investigated associations between metals and thyroiditis antibody status. Healthy individuals ( n = 1104) completed a questionnaire and underwent checkups of anthropometric parameters, thyroid function status, and levels of seven metals in blood (magnesium, iron, calcium, copper, zinc, manganese, and lead). Associated profiles of glyco- and lipid metabolism were also established. Logistic regression and restricted cubic spline (RCS) regression analysis were applied to adjudge associations between metals and TPOAb and TgAb status. It was found that, after adjusting for likely cofounding factors, participants with antibody positivity had significantly lower serum concentrations of magnesium and iron. When serum magnesium levels were analyzed in quartiles, the odds ratios of quartile 4 were 0.329–fold (95% confidence interval (CI): 0.167–0647) and 0.259-fold (95% CI 0.177–0.574) that of quartile 1 regarding TPOAb and TgAb positivity ( P = 0.004, 0.003). After adjustment, the RCS analysis detected nonlinear associations between iron and TPOAb and TgAb positivity ( P < 0.01, both). In stratified analyses, these associations regarding magnesium and iron remained for women of reproductive age, but not for postmenopausal women and men. We conclude that lower serum levels of magnesium and iron are associated with incremental positivity of thyroiditis antibodies and may be among the most important metals contributing to AIT in women of reproductive age.

Identification of serum metabolites enhancing inflammatory responses in COVID-19 - Chen-Song Zhang; Bingchang Zhang; Mengqi Li; Xiaoyan Wei; Kai Gong; Zhiyong Li; Xiangyang Yao; Jianfeng Wu; Cixiong Zhang; Mingxia Zhu; Lei Zhang; Xiufeng Sun; et al. (Science China Life Sciences, 2022)

Oncogenic GBX2 promotes the malignant behaviors of bladder cancer cells by binding to the ITGA5 promoter and activating its transcription - Yaoyao Xiong; Xiaohang Song; Kudusi; Xiongbing Zu; Minfeng Chen; Wei He; Lin Qi (Functional & Integrative Genomics, 2022)

Clinical profiles and antimicrobial resistance patterns of invasive Salmonella infections in children in China - Wen Song; Qingwen Shan; Yue Qiu; Xianyao Lin; Chunhui Zhu; Zhiqiang Zhuo; Caihong Wang; Jianning Tong; Rui Li; Chaomin Wan; Yu Zhu; Minxia Chen; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2022)
Invasive Salmonella infections result in a significant burden of disease including morbidity, mortality, and financial cost in many countries. Besides typhoid fever, the clinical impact of non-typhoid Salmonella infections is increasingly recognized with the improvement of laboratory detection capacity and techniques. A retrospective multicenter study was conducted to analyze the clinical profiles and antimicrobial resistance patterns of invasive Salmonella infections in hospitalized children in China during 2016–2018. A total of 130 children with invasive Salmonella infections were included with the median age of 12 months (range: 1–144 months). Seventy-nine percent of cases occurred between May and October. Pneumonia was the most common comorbidity in 33 (25.4%) patients. Meningitis and septic arthritis caused by nontyphoidal Salmonella (NTS) infections occurred in 12 (9.2%) patients and 5 (3.8%) patients. Patients < 12 months (OR: 16.04) and with septic shock (OR: 23.4), vomit (OR: 13.33), convulsion (OR: 15.86), C-reactive protein (CRP) ≥ 40 g/L (OR: 5.56), and a higher level of procalcitonin (PCT) (OR: 1.05) on admission were statistically associated to an increased risk of developing meningitis. Compared to 114 patients with NTS infections , 16 patients with typhoid fever presented with higher levels of CRP and PCT ( P < 0.05). The rates of resistance to ampicillin, sulfamethoxazole/trimethoprim, ciprofloxacin, and ceftriaxone among Salmonella Typhi and NTS isolates were 50% vs 57.3%, 9.1% vs 24.8%, 0% vs 11.2%, and 0% vs 9.9%, respectively. NTS has been the major cause of invasive Salmonella infections in Chinese children and can result in severe diseases. Antimicrobial resistance among NTS was more common.

Distribution, sources, and ecological risk of organophosphate esters in the urbanized Jiaozhou Bay, East China - Jianing Lin; Lutao Zhang; Mingxing Zhang; Heng Zhang; Changsheng Guo; Song Feng; Jian Xu (Environmental Science and Pollution Research, 2022)

Sestrin2 attenuates renal damage by regulating Hippo pathway in diabetic nephropathy - Yawei Bian; Chonglin Shi; Shan Song; Lin Mu; Ming Wu; Duojun Qiu; Jiajia Dong; Wei Zhang; Chen Yuan; Dongyun Wang; Zihui Zhou; Xuan Dong; et al. (Cell and Tissue Research, 2022)

Acanthopagrus oconnorae , a new species of seabream (Sparidae) from the Red Sea - Lucía Pombo‐Ayora; Viktor N. Peinemann; Collin T. Williams; Song He; Yu Jia Lin; Yukio Iwatsuki; Donal D. C. Bradley; Michael L. Berumen (Journal of Fish Biology, 2022)
A new species of sparid fish, Acanthopagrus oconnorae , is described based on 11 specimens collected in the shallow (0–1 m depth) mangrove‐adjacent sandflats of Thuwal, Saudi Arabia. The new species is distinguished from its congeners by the following combination of characters: second anal‐fin spine 12.8%–16.6% of standard length (SL); 3½ scale rows between the fifth dorsal‐fin spine and lateral line; suborbital width 5.7%–6.7% of SL; eyes positioned at the anterior edge of the head, often forming a weakly convex break in an otherwise gently curved head profile, when viewed laterally; caudal fin light yellow with black posterior margin (approximately half of fin); anal fin dusky grey, with posterior one‐fifth of the fin light yellow; black streaks on inter‐radial membranes of anal fin absent. The most similar species to A. oconnorae is Acanthopagrus vagus , which differs by the presence of a w‐shaped anterior edge of the scaled predorsal area, a more acute snout and black streaks on the inter‐radial membranes of the anal fin. Phylogenetic placement and species delimitation of A. oconnorae are discussed based on COI, CytB and 16S sequences. It is hypothesized that ecology and behaviour explain how this species avoided detection despite its likely occurrence in coastal areas of the Red Sea with historically high fishing pressure.

The differential impact of air pollutants on acute urticaria and chronic urticaria: a time series analysis - Jiawei Li; Guoqiang Song; Zhenzhen Mu; Xiaoou Lan; Fan Yang; Lin Li; Xiuping Han (Environmental Science and Pollution Research, 2022)

Scrutinizing the interaction between metribuzin with glutathione reductase 2 from Arabidopsis thaliana: insight into the molecular toxicity in agriculture - Dongmei Xiang; Lin Zhu; Song Yang; Xiaomin Hou (Environmental Science and Pollution Research, 2022)

The role of MeCP2 and the BDNF/TrkB signaling pathway in the stress resilience of mice subjected to CSDS - Lixuan Huang; Lujuan He; Ruijia Ma; Wanzhao Ding; Chan Zhou; Song Lin; Ji-chun Zhang; Jiaxu Chen; Wei Yao (Psychopharmacology, 2022)

Geochronology and structural deformation of Precambrian metamorphic basement in the eastern Jiangnan orogenic belt: constraints on the assembly time of the Yangtze and Cathaysia blocks - Yangyang Wang; Chuanzhong Song; Jiahao Li; Shoufa Lin; Zhenwei Li; Fang Yuan; Shenglian Ren (Earth Science Informatics, 2022)

Upper bound limit analysis for 3D slope stability analysis based on rigid block structure - Xiao-Gang Wang; Xing-Chao Lin; Xing-Song Sun (Bulletin of Engineering Geology and the Environment, 2022)

Effects of soil organic matter components and iron aluminum oxides on aggregate stability during vegetation succession in granite red soil eroded areas - Zhe Lin; Zhi-gang Huang; Da-lan Liao; Wan-xia Huang; Juan Huang; Yu-song Deng (Journal of Mountain Science, 2022)

Cluster analysis of the domain of microseismic event attributes for floor water inrush warning in the working face - Guo-Jun Shang; Xiao-Fei Liu; Li Li; Li-Song Zhao; Jin-Song Shen; Wei-Lin Huang (Applied Geophysics, 2022)

Spatial patterns and driving factors of carbon stocks in mangrove forests on Hainan Island, China - Yuchen Meng; Ruikun Gou; Jiankun Bai; David Moreno‐Mateos; Charles C. Davis; Luoma Wan; Shanshan Song; Hongsheng Zhang; Xiaoshan Zhu; Guanghui Lin (Global Ecology and Biogeography, 2022)
Aim Mangrove forests are important coastal wetlands for the blue carbon budget and play a significant role in mitigating global climate change. However, spatial patterns of carbon stocks in mangrove forests on an island scale have not been quantified owing to methodological limitations and lack of understanding of controlling factors. We took the entire Hainan Island as a case study and aimed to carry out a comprehensive investigation of the spatial patterns and driving factors of carbon stocks in mangrove forests. Location Southern China. Time period 2017–2020. Major taxa studied Mangrove forest. Methods The upscaling method combined with field surveys and Sentinel‐2 imagery analysis were used to compare different models for optimization of mangrove ecosystem carbon stock estimations. We also used structural equation modelling (SEM) to evaluate the factors driving the distributional patterns of mangrove carbon stocks on an island scale. Results The current total mangrove carbon stock of the entire Hainan Island was estimated to be 703,181 Mg C (with a mean density of 192 Mg C/ha), with the above‐ and below‐ground carbon stocks averaging at 44.7 and 147.3 Mg C/ha, respectively. The mangrove carbon storage in the north‐eastern region of the island was the highest and in the west region the lowest. Sediment nitrogen content and plant species diversity had the most positive driving effects on the distribution of total carbon stock for Hainan Island mangroves. Main conclusions The combination of field surveys and Sentinel‐2 imagery analysis can be applied to regional‐scale estimations of carbon stocks for mangrove forests. Spatial pattens of mangrove carbon stocks vary among locations on Hainan Island, and soil nutrient (especially nitrogen) availability is the dominant factor regulating carbon stock variations along the land‐to‐sea gradient. Our findings have significant implications for better understanding the distribution of mangrove carbon stocks and quantification of the global blue carbon budget.

FAM135B: a new player in DNA damage response - Chunyu Song; Lin Deng (Genome Instability & Disease, 2022)

First report of Sclerotinia sclerotiorum on Atractylodes lancea in China - Feng Han; Jing Huang; Maoxiang Lin; Xuhong Song (Journal of Plant Pathology, 2022)

Understorey light environment impacts on seedling establishment and growth in a typhoon-disturbed tropical forest - Kuo-Jung Chao; Yung-Chiau Lin; Guo-Zhang Michael Song; Chien-Hui Liao; Yau-Lun Kuo; Chang-Fu Hsieh; Eugene W. Schupp (Plant Ecology, 2022)

Catalpol Ameliorates Neurotoxicity in N2a/APP695swe Cells and APP/PS1 Transgenic Mice - Jikun Du; Jierong Liu; Xiaoman Huang; Yuanhua Li; Daibo Song; Qin Li; Jiantao Lin; Baohong Li; Li Li (Neurotoxicity Research, 2022)

Metabolomics analysis of the potential toxicological mechanisms of diquat dibromide herbicide in adult zebrafish (Danio rerio) liver - Ye Xiao; Xiang Lin; Meilan Zhou; Tianyu Ren; Ruili Gao; Zhongqun Liu; Wenjing Shen; Rong Wang; Xi Xie; Yanting Song; Wenting Hu (Fish Physiology and Biochemistry, 2022)

Preparation and Evaluation of a Microsponge Dermal Stratum Corneum Retention Drug Delivery System for Griseofulvin - Lin Ma; Song Guo; Jingshu Piao; Mingguan Piao (AAPS PharmSciTech, 2022)

Fissistiganoids A and B: two new flavonoids from the Fissistigma tungfangense - Wan-Lin Zhong; Xue-Ming Zhou; Ji-Ling Yi; Xin-Ming Song; Bin Zhang; Jing-Yu Yang; Guang-Ying Chen (Natural Product Research, 2022)

Loss of anthocyanidin synthase gene is associated with white flowers of Salvia miltiorrhiza Bge. f. alba, a natural variant of S. miltiorrhiza - Caicai Lin; Piyi Xing; Hua Jin; Changhao Zhou; Xingfeng Li; Zhenqiao Song (Planta, 2022)

PPARγ Dysfunction in the Medial Prefrontal Cortex Mediates High-Fat Diet-Induced Depression - Cong-Cong Fu; Xin-Yi Zhang; Liu Xu; Hui-Xian Huang; Shuang Xu; Qiao-Qi Wu; Zhen Wang; Xi Gu; Li-Fang Lin; Song Lin; Ying-Ying Fang; Xiong Cao; et al. (Molecular Neurobiology, 2022)

Peroxisome proliferator-activator receptor γ and psoriasis, molecular and cellular biochemistry - Xiran Lin; Xianmin Meng; Zhiqi Song; Jingrong Lin (Molecular and Cellular Biochemistry, 2022)

Microwave-assisted preparation of cotton stem-derived activated carbon for dye removal from synthetic wastewater - Jin Lin; Saidan Zhao; Song Cheng (Environmental Science and Pollution Research, 2022)

Testing the transfer functions for the Geonor T-200B and Chinese standard precipitation gauge in the central Qinghai—Tibet Plateau - Le-le Zhang; Li-ming Gao; Ji Chen; Lin Zhao; Ke-long Chen; Jing-yi Zhao; Guo-jun Liu; Ting-xi Song; Yan-kun Li (Journal of Mountain Science, 2022)

Aquapteridospora jiangxiensis, a new aquatic hyphomycetous fungus from a freshwater habitat in China - Su-Qin Peng; Yu-Lin Liu; Jun-En Huang; Xiao-Hong Li; Xin-Yi Yan; Hai-Yan Song; Yang Gao; Zhi-Jun Zhai; Yuan-Qiu Liu; Dian-Ming Hu (Archives of Microbiology, 2022)

Live on the land and fed by the sea: diverse subsistence economies in the Neolithic Dawenkou Period in Shandong Peninsula, China - Minghao Lin; Yanbo Song; Fen Wang; Zebing Wang; Songtao Chen (Archaeological and Anthropological Sciences, 2022)

Biflavonoids from the twigs and leaves of Cephalotaxus oliveri Mast. and their α -glucosidase inhibitory activity - Min Song; Tong Xiao; Qiu-Shuang Wu; Hang Fai Kwok; Ging Chan; Li-Gen Lin; Xiao-Qi Zhang; Wen-Cai Ye; Sheng-Jiang He; Qing-Wen Zhang (Natural Product Research, 2022)

Estimating the Impact of a Seasonal Fishing Moratorium on the East China Sea Ecosystem From 1997 to 2018 - Lingyan Xu; Puqing Song; Yuyu Wang; Bin Xie; Lingfeng Huang; Yuan Li; Xinqing Zheng; Longshan Lin (Frontiers in Marine Science, 2022)
Fisheries management policies (FMPs) have been implemented in coastal countries to ensure a sustainable supply of seafood and the recovery of species diversity. Because of the depletion of fishery stocks, China has introduced a series of FMPs since 1995, including a seasonal fishing moratorium (SFM), a zero-growth strategy, and a minimum mesh size for fishing nets. Here, we built two mass balance models for 1997–2000 (M1997) and 2018–2019 (M2018) using Ecopath with Ecosim 6.6 to illustrate the interannual changes over the past two decades in the East China Sea (ECS). We then simulated two dynamic scenarios from 1997 to 2018, SFM (M2018 SFM ) and no SFM (M2018 no-SFM ), to test the role of the SFM under fishing pressure in the ECS. Ecopath showed that the ECS ecosystem is becoming more mature, although it is still unstable, featuring lower total primary production/total respiration, longer cycles, faster organic material circulation speed, and a higher omnivorous degree. This suggests a slow recovery for the ECS ecosystem in the past two decades. The biomass of fish in the ECS—especially the planktivores, dominated by small-sized Benthosema pterotum —significantly increased in M2018 versus M1997, but there were fewer medium- and large-sized fish. The keystone species switched from the planktivores/piscivores dominated by Decapterus maruadsi in M1997 to planktivores in M2018. Ecosim illustrated that the SFM has positive effects on fishery resources recovery, especially for commercial fishes (i.e., large yellow croakers and hairtails), as reflected by the significantly higher predicted biomass of fish in M2018 SFM compared to M2018 no-SFM and M1997, although the bioaccumulation was consumed by the intense fishing pressure after the SFM. However, the M2018 SFM prediction for nektons was still lower than the actual value, especially for planktivores, which display a sharp increase in biomass. This should be partly attributable to the policy of the minimum mesh size (<5 cm was banned), which benefits B. pterotum due to its 3.5 cm maximum body size. Therefore, a series of FMPs, rather than only the SFM, functioned together in the ECS ecosystem. However, the mixed trophic impact indicated a negative impact if the fisheries were further developed. Fishery management in the ECS needs to be strengthened by extending the SFM and reducing fishing pressure after the SFM.

Transcriptome Changes Induced by Botrytis cinerea Stress and Weighted Gene Co-expression Network Analysis (WGCNA) in Actinidia chinensis - Zhe-Xin Li; Wen-Lin Zhang; Deng-Wei Jue; Xia Liu; Yu-Song Jiang; Jian-Min Tang (Plant Molecular Biology Reporter, 2022)

Overexpression of BpERF1.1 in Betula Platyphylla enhanced tolerance to multiple abiotic stresses - Xiang Zhang; Xin Lin; Song Chen; Su Chen (Physiology and Molecular Biology of Plants, 2022)

Contrasting Anomaly Patterns of Magmatic–Hydrothermal Polymetallic and Orogenic Gold Deposits and their Suitable Exploration Methods: A Case Study from the Qinling Orogen - Yiwei Song; Lin Yang; Emmanuel John M. Carranza; Leon Bagas; Yongbao Gao; Biao Sun; Peng Wang (Natural Resources Research, 2022)

Grazing by Tibetan Sheep Enhances Soil Bacterial and Fungal Diversity in Cold Season Pastures of Alpine Meadows on the Northern Qinghai–Tibetan Plateau - Lin Wang; Xiaojun Yu; Changlin Xu; Yuanyuan Jing; Meijuan Song (Journal of Soil Science and Plant Nutrition, 2022)

Priming of rice defense against a sap-sucking insect pest brown planthopper by silicon - Yibin Lin; Xianhui Lin; Chaohui Ding; Ming Xia; Rongrong Xue; Zhongxiang Sun; Daoqian Chen; Keyan Zhu-Salzman; Rensen Zeng; Yuanyuan Song (Journal of Pest Science, 2022)

Combined System of Organic Substrate and Straw-Degrading Microbial Agents Improved Soil Organic Matter Levels and Microbial Abundance in a Rice–Wheat Rotation - Shi-Li Song; Xue Luo; Hao Wu; Xiao-Lin Lu; Fang-Ji Xu; Zhen-Hua Zhang; Yong-Xiang Guan; Chuan-Chao Dai (Current Microbiology, 2022)

Investigation on long-term progressive deformation of engineering slope based on comprehensive monitoring - Shi-shu Zhang; Song-feng Guo; Sheng-wen Qi; Feng-jiao Tang; Jin-shan Hu; Xiao-ping Zhao; Cong-yan Ran; Xin Wang; Yu Zou; Xiao-lin Huang; Bo-wen Zheng; Ning Liang (Journal of Mountain Science, 2022)

SmGDB: genome database of Salvia miltiorrhiza, an important TCM Plant - Changhao Zhou; Caicai Lin; Piyi Xing; Xingfeng Li; Zhenqiao Song (Genes & Genomics, 2022)

Distribution and invasion of Spartina alterniflora within the Jiaozhou Bay monitored by remote sensing image - Jianbu Wang; Zhaoyang Lin; Yuanqing Ma; Guangbo Ren; Zijun Xu; Xiukai Song; Yi Ma; Andong Wang; Yajie Zhao (Acta Oceanologica Sinica, 2022)

Massive Heat Shock Protein 70 Genes Expansion and Transcriptional Signatures Uncover Hard Clam Adaptations to Heat and Hypoxia - Zhi Hu; Hao Song; Jie Feng; Cong Zhou; Mei-Jie Yang; Pu Shi; Zheng-Lin Yu; Yong-Ren Li; Yong-Jun Guo; Hai-Zhou Li; Tao Zhang (Frontiers in Marine Science, 2022)
Heat shock protein 70 (HSP70) members participate in a wide range of housekeeping and stress-related activities in eukaryotic cells. In marine ecosystems, bivalves encounter abiotic stresses, including high temperatures and low dissolved oxygen. Here, 133 MmHSP70 genes were identified through combined methods including Blastp, HMM and manual filtration, based on the whole Mercenaria mercenaria genome. The MmHSP70 genes were unevenly distributed, and 41 genes (33.08%) were located on Chr 7. Phylogenetic analyses indicated that the MmHSP70 gene family mainly consisted of two clusters and the Hspa12 subfamily underwent lineage-specific expansion. A high-density collinear gene block was observed between M. mercenaria Chr 7 and Cyclina sinensis Chr 14. Tandem duplication MmHSP70 gene pairs experienced different levels of purifying selection, which could be an important source of sequence and functional constraints. MmHSP70 genes showed tissue-specific and stress-specific expression. Most tandem duplication HSP70 gene pairs had high expression under hypoxia stress. HSP70 B2 tandem duplication gene pairs showed significantly increased expression under heat plus severe hypoxia stress. This study provided a comprehensive understanding of the MmHSP70 gene family in the M. mercenaria and laid a significant foundation for further studies on the functional characteristics of MmHSP70 genes during exposure to heat and hypoxia stress.

Editorial: Omics and Fish Nutrition - Kang-le Lu; Samad Rahimnejad; Song-lin Li (Frontiers in Marine Science, 2022)

Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight - Yu-Qian Song; Shi-Di Hu; Xu Lin; Xiang-He Meng; Xiao Wang; Yin-Hua Zhang; Cheng Peng; Rui Gong; Tao Xu; Tong Zhang; Chen-Zhong Li; Dao-Yan Pan; et al. (Journal of Molecular Medicine, 2022)
An increasing number of epidemiological studies have suggested that birth weight (BW) may be a determinant of bone health later in life, although the underlying genetic mechanism remains unclear. Here, we applied a pleiotropic conditional false discovery rate (cFDR) approach to the genome-wide association study (GWAS) summary statistics for lumbar spine bone mineral density (LS BMD) and BW, aiming to identify novel susceptibility variants shared between these two traits. We detected 5 novel potential pleiotropic loci which are located at or near 7 different genes ( NTAN1 , PDXDC1 , CACNA1G , JAG1 , FAT1P1 , CCDC170 , ESR1 ), among which PDXDC1 and FAT1P1 have not previously been linked to these phenotypes. To partially validate the findings, we demonstrated that the expression of PDXDC1 was dramatically reduced in ovariectomized (OVX) mice in comparison with sham-operated (SHAM) mice in both the growth plate and trabecula bone. Furthermore, immunohistochemistry assay with serial sections showed that both osteoclasts and osteoblasts express PDXDC1 , supporting its potential role in bone metabolism. In conclusion, our study provides insights into some shared genetic mechanisms for BMD and BW as well as a novel potential therapeutic target for the prevention of OP in the early stages of the disease development. Key messages We investigated pleiotropy-informed enrichment between LS BMD and BW. We identified genetic variants related to both LS BMD and BW by utilizing a cFDR approach. PDXDC1 is a novel pleiotropic gene which may be related to both LS BMD and BW. Elevated expression of PDXDC1 is related to higher BMD and lower ratio n-6/n-3 PUFA indicating a bone protective effect of PDXDC1.

Poor evidence for host-dependent regular RNA editing in the transcriptome of SARS-CoV-2 - Jinbao Zong; Yanping Zhang; Fenfen Guo; Changyuan Wang; Hong Li; Gaoyang Lin; Wenqing Jiang; Xiaoping Song; Xiufang Zhang; Feng Huang; Min Qi; Xin Zheng (Journal of Applied Genetics, 2022)

The genes for sensory perception of sound should be considered in gene diagnosis of congenital sensorineural hearing loss and microtia - Ken Lin; Ding-Yun You; Li-Huan Zhang; Li-Juan Zhou; Jin-Yan Zu; Yang Xiao; Mei-Hua Sun; Dong-Su; Xue Cao; Tie-Song Zhang; Jing Ma (Journal of Applied Genetics, 2022)

An implementation framework of blockchain-based hazardous waste transfer management system - Guanghan Song; Yujie Lu; Haibo Feng; Han Lin; Yang Zheng (Environmental Science and Pollution Research, 2022)

Responses of nitrous oxide fluxes to autumn freeze–thaw cycles in permafrost peatlands of the Da Xing’an Mountains, Northeast China - Liquan Song; Shuying Zang; Lin Lin; Boquan Lu; Chaofeng Sun; Yaqing Jiao; Hanxi Wang (Environmental Science and Pollution Research, 2022)

Attribution of the seasonality of atmospheric heating changes over the western tropical Pacific with a focus on the spring season - Shuheng Lin; Song Yang; Shan He; Zhenning Li; Jiaxin Chen; Wenjie Dong; Jiaxue Wu (Climate Dynamics, 2022)
Atmospheric diabatic heating, a major driving force of atmospheric circulation over the tropics, is strongly confined to the tropical western North Pacific (TWNP) region, with the global warmest sea surface temperature (SST). The changes in diabatic heating over the TWNP, which exert great impacts on the global climate system, have recently exhibited a noticeable seasonal dependence with a remarkable increase in boreal spring. In this study, we applied observations, reanalysis data, and numerical experiments to investigate the causes of the seasonality in heating changes. Results show that in boreal spring convection is more sensitive to the TWNP SST, leading to a more significant enhancement of deep convection, although the increase in the SST is nearly the same as that in the other seasons. In the non-spring seasons, the enhanced convection due to increased local SST is suppressed by the anomalous anticyclonic wind shear over the TWNP, generated by the easterly wind anomalies induced by the tropical Indian Ocean (TIO) warming via the Kevin waves. However, the TIO warming does not show any suppressing effect in spring because it is much weaker than that in the other seasons and thus the warming itself cannot induce sufficient convective heating anomalies to excite the Kelvin waves.

Effects of Microplastics on Microbial Community in Zhanjiang Mangrove Sediments - Meng-Meng Chen; Fang-Hong Nie; Aftab Qamar; Di-hua Zhu; Yao Hu; Min Zhang; Qing-Lang Song; Hong-Ying Lin; Zhi-Bao Chen; Su-Qing Liu; Jin-Jun Chen (Bulletin of Environmental Contamination and Toxicology, 2022)

Insights into the ecology of Schizosaccharomyces species in natural and artificial habitats - Michael Brysch-Herzberg; Guo-Song Jia; Martin Seidel; Imen Assali; Li-Lin Du (Antonie van Leeuwenhoek, 2022)
The fission yeast genus Schizosaccharomyces contains important model organisms for biological research. In particular, S. pombe is a widely used model eukaryote. So far little is known about the natural and artificial habitats of species in this genus. Finding out where S. pombe and other fission yeast species occur and how they live in their habitats can promote better understanding of their biology. Here we investigate in which substrates S. pombe , S. octosporus , S. osmophilus and S. japonicus are present. To this end about 2100 samples consisting of soil, tree sap fluxes, fresh fruit, dried fruit, honey, cacao beans, molasses and other substrates were analyzed. Effective isolation methods that allow efficient isolation of the above mentioned species were developed. Based on the frequency of isolating different fission yeast species in various substrates and on extensive literature survey, conclusions are drawn on their ecology. The results suggest that the primary habitat of S. pombe and S. octosporus is honeybee honey. Both species were also frequently detected on certain dried fruit like raisins, mango or pineapple to which they could be brought by the honey bees during ripening or during drying. While S. pombe was regularly isolated from grape mash and from fermented raw cacao beans S. octosporus was never isolated from fresh fruit. The main habitat of S. osmophilus seems to be solitary bee beebread. It was rarely isolated from raisins. S. japonicus was mainly found in forest substrates although it occurs on fruit and in fruit fermentations, too.

Midkine promotes breast cancer cell proliferation and migration by upregulating NR3C1 expression and activating the NF-κB pathway - Lin Zhang; Li Song; Yanyan Xu; Yuting Xu; Maojin Zheng; Peng Zhang; Qingling Wang (Molecular Biology Reports, 2022)

Follicular Fluid-Derived Exosomal MicroRNA-18b-5p Regulates PTEN-Mediated PI3K/Akt/mTOR Signaling Pathway to Inhibit Polycystic Ovary Syndrome Development - Zhi Zhou; Zhihua Tu; Juan Zhang; Can tan; Xiaoyong Shen; Bangbei Wan; Yejuan Li; Anguo Wang; Liqiang Zhao; Jiajia Hu; Ning Ma; Jing Zhou; et al. (Molecular Neurobiology, 2022)

MiR-361-3p alleviates cerebral ischemia–reperfusion injury by targeting NACC1 through the PINK1/Parkin pathway - Xihong Ye; Hua Song; Huimin Hu; Chunli Zhou; Qinyi Chen; Lin Hong; Min Huang; Hongfei Zhu (Journal of Molecular Histology, 2022)

Pollution characteristics and emissions of typical organophosphate esters of a wastewater treatment plant - Hongling Yin; Yi Luo; Jiaojiao Song; Shiping Li; Shuyu Lin; Yuanming Xiong; Shuhong Fang; Juan Tang (Environmental Science and Pollution Research, 2022)

Effects of Environmental and Spatial Variables on Bacteria in Zhanjiang Mangrove Sediments - Di-Hua Zhu; Qing-Lang Song; Fang-Hong Nie; Wan Wei; Meng-Meng Chen; Min Zhang; Hong-Ying Lin; Dan-Ju Kang; Zhi-Bao Chen; Anthony G. Hay; Jin-Jun Chen (Current Microbiology, 2022)

IgE Reactivity of Potential Allergens from the Swimming Crab Portunus trituberculatus and the Research of ELISA Reagent for Detecting Crab Food Anaphylaxis - Xueni Qiu; Qiongyan Zhou; Xiaoxia Zhu; Wei Lin; Changkao Mu; Ronghua Li; Yangfang Ye; Weiwei Song; Ce Shi; Lei Liu; Huan Wang; Chunlin Wang; et al. (Journal of Ocean University of China, 2022)

Genetic and genomic characterization of multidrug resistant Bacillus subtilis M3 isolated from an activated sludge reactor treating wastewater - Hafeez Ul Haq; Wei Huang; Ye Li; Ting Zhang; Shaocheng Ma; Yajing Zhang; Yongkang Song; Daiyan Lin; Baoyu Tian (Biologia, 2022)

Glacier lanternfish (Benthosema glaciale) first found on the continental slope of the Pacific Arctic - Ran Zhang; Yuan Li; Qiaohong Liu; Puqing Song; Hai Li; Rui Wang; Shaoxiong Ding; Longshan Lin (Polar Biology, 2022)

Legacy effects of a multi-year extreme drought on belowground bud banks in rhizomatous vs bunchgrass-dominated grasslands - Jianqiang Qian; Ziyue Guo; Taofeek O. Muraina; Niwu Te; Robert J. Griffin-Nolan; Lin Song; Chong Xu; Qiang Yu; Zhiming Zhang; Wentao Luo (Oecologia, 2022)

Synthesis, Characterization of NR@SiO2/PNIPAm-co-Ppa Composite Nanogel and Study On Its Application in Photodynamic Therapy - Zirui Wang; Qiusheng Song; Lin Zhu; Chengyan Zhao; Haihong Ma (Journal of Fluorescence, 2022)

Low-cost Imaging of Fluorescent DNA in Agarose Gel Electrophoresis using Raspberry Pi cameras - Hassan Ali Abid; Jian Wern Ong; Eric Shen Lin; Zhixiong Song; Oi Wah Liew; Tuck Wah Ng (Journal of Fluorescence, 2022)
Low-cost analytical solutions built around microcomputers like the Raspberry Pi help to facilitate laboratory investigations in resource limited venues. Here, three camera modules (V1.3 with and without filter, as well as NoIR) that work with this microcomputer were assessed for their suitability in imaging fluorescent DNA following agarose gel electrophoresis. Evaluation of their utility was based on signal-to-noise (SNR) and noise variance metrics that were developed. Experiments conducted with samples were subjected to Polymerase Chain Reaction (PCR), and the amplified products were separated using gel electrophoresis and stained with Midori green. Image analysis revealed the NoIR camera performed the best with SNR and noise variance values of 21.7 and 0.222 respectively. In experiments conducted using UV LED lighting to simulate ethidium bromide (EtBr) excitation, the NoIR and V1.3 with filter removed cameras showed comparable SNR values.

Optimizing river damming and impounding strategies to mitigate seawater intrusion in the coastal aquifer of Dagu River Basin, China - Di Zhang; Yun Yang; Jian Song; Jianfeng Wu; Xiaomin Sun; Jin Lin; Xiaobin Zhu; Jichun Wu (Hydrogeology Journal, 2022)

Air pollution and hospital admissions for critical illness in emergency department: a tertiary-center research in Changsha, China, 2016–2020 - Hang Lin; Yong Long; Yingjie Su; Kun Song; Changluo Li; Ning Ding (Environmental Science and Pollution Research, 2022)

The associations of urinary DEHP metabolite levels, serum thyroid hormones, and thyroid-related genes among the adolescent students from China: a cross-sectional study - Yaming Zhao; Xinyue Song; Shuang Ding; Wen Qi; Yuezhu Zhang; Qi Xu; Tianyang Zhao; Xueting Zhang; Xu Li; Fuju Wu; Lin Ye (Environmental Science and Pollution Research, 2022)

Distributions, origins, and health-risk assessment of nitrate in groundwater in typical alluvial-pluvial fans, North China Plain - Lin Gan; Guanxing Huang; Lixin Pei; Yanjing Gan; Chunyan Liu; Mingnan Yang; Dongya Han; Jiangmin Song (Environmental Science and Pollution Research, 2022)

Very Low Stocks and Inputs of Necromass in Wind-affected Tropical Forests - Kuo-Jung Chao; Pin-Siou Liao; Yi-Sheng Chen; Guo-Zhang Michael Song; Oliver L. Phillips; Hsing-Juh Lin (Ecosystems, 2022)

Demersal fish diversity and molecular taxonomy in the Bering Sea and Chukchi Sea - Hai Li; Fang Yang; Xuehua Wang; Yuan Li; Nan Zhang; Ran Zhang; Cheng Liu; Hushun Zhang; Longshan Lin; Puqing Song (Conservation Genetics Resources, 2022)

Spatio-temporal characteristics of demersal fish community in the Chukchi and northern Bering Seas: significant distributional records and interannual variations in species composition and biodiversity - Ran Zhang; Puqing Song; Hai Li; Rui Wang; Yuan Li; Xing Miao; Longshan Lin; Shaoxiong Ding (Polar Biology, 2022)

Upregulation of h-TERT and Ki-67 in ectopic endometrium is associated with recurrence of endometriosis - Jie Luo; Zhimin Song; Tao Zhang; Ketan Chu; Jingyi Li; Jianhong Zhou; Jun Lin (Journal of Zhejiang University-SCIENCE B, 2022)

Glomalin-related soil protein (GRSP) in metal sequestration at Pb/Zn-contaminated sites - Lang Qiu; Hanzhi Lin; Benru Song; Tianle Kong; Weimin Sun; Xiaoxu Sun; Yanxu Zhang; Baoqin Li (Journal of Soils and Sediments, 2022)

Functional characterization of melanocortin-3 receptor in rainbow trout (Oncorhynchus mykiss) - Hui-Xia Yu; Yang Li; Wei-Jia Song; Hui Wang; Hao-Lin Mo; Qiao Liu; Xin-Miao Zhang; Ze-Bin Jiang; Li-Xin Wang (Fish Physiology and Biochemistry, 2022)

Airborne black carbon variations during the COVID-19 lockdown in the Yangtze River Delta megacities suggest actions to curb global warming - Hao Li; Kan Huang; Qingyan Fu; Yanfen Lin; Jia Chen; Congrui Deng; Xudong Tian; Qian Tang; Qingchuan Song; Zhen Wei (Environmental Chemistry Letters, 2022)

The Flavor and Antioxidant Activity Change Pattern of Shrimp Head Paste During Fermentation - Jing Yu; Kuan Lu; Jinyuan Sun; Wancui Xie; Lin Song; Hongxia Che (Journal of Ocean University of China, 2022)

Dimeric hexylitaconic acids from the marine-derived fungus Aspergillus welwitschiae CUGBMF180262 - Jiahui Han; Na Yang; Shangzhu Wei; Jia Jia; Rui Lin; Jiangpeng Li; Hongkai Bi; Fuhang Song; Xiuli Xu (Natural Product Research, 2022)

Structure reassignment of two triterpenes with CASE algorithms and DFT chemical shift predictions - Zhi-Kang Duan; Tian-Ming Lv; Guan-Shan Song; Yu-Xi Wang; Bin Lin; Xiao-Xiao Huang (Natural Product Research, 2022)

Biochanin A as an α-hemolysin inhibitor for combating methicillin-resistant Staphylococcus aureus infection - Jiaxuan Feng; Dazhong Sun; Li Wang; Xueting Li; Jiyu Guan; Lin Wei; Donghui Yue; Xingye Wang; Yicheng Zhao; Haimiao Yang; Wu Song; Bingmei Wang (World Journal of Microbiology and Biotechnology, 2022)

Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity - Junyan Han; Ning Zhang; Danying Chen; Yuhuan Gong; Guoli Li; Yaxian Kong; Lin Pu; Chen Chen; Jingyuan Liu; Qi Wang; Ju Zhang; Xuesen Zhao; et al. (Science China Life Sciences, 2022)

Nakamurella leprariae sp. nov., isolated from a lichen sample - De-Feng An; Shao-Juan Yang; Long-Qian Jiang; Xin-Yu Wang; Xiao-Yu Huang; Lei Lang; Xue-Mei Chen; Ming-Qun Fan; Gui-Ding Li; Ming-Guo Jiang; Li-Song Wang; Cheng-Lin Jiang; et al. (Archives of Microbiology, 2022)

Genome-wide identification and expression analysis of glycosyltransferase gene family 1 in Quercus robur L. - Jie Zhang; Li-Mei Lin; Wen-Wen Cheng; Xin Song; Yue-Hong Long; Zhao-Bin Xing (Journal of Applied Genetics, 2021)

Prussian blue modified CeO2 as a heterogeneous photo-Fenton-like catalyst for degradation of norfloxacin in water - Ruyi Xiao; Yuanyuan Zhang; Shuangfei Wang; Hongxiang Zhu; Hainong Song; Guoning Chen; Hongfei Lin; Jian Zhang; Jianhua Xiong (Environmental Science and Pollution Research, 2021)

Citric acid and AMF inoculation combination–assisted phytoextraction of vanadium (V) by Medicago sativa in V mining contaminated soil - Lang Qiu; Wenlong Gao; Zhigang Wang; Baoqin Li; Weimin Sun; Pin Gao; Xiaoxu Sun; Benru Song; Yanxu Zhang; Tianle Kong; Hanzhi Lin (Environmental Science and Pollution Research, 2021)

MiR-34b-3p Impaired HUVECs Viability and Migration via Targeting PDK1 in an In Vitro Model of Gestational Diabetes Mellitus - Feiluan Song; Anli Cai; Qianwen Ye; Xiang Chen; Lin Lin; Xi Hao (Biochemical Genetics, 2021)

Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Bernard R. Agwanda; Rim Al Kubrusli; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Christopher F. Basler; et al. (Archives of Virology, 2021)

Chemical constituents from the barks of Melia azedarach and their PTP1B inhibitory activity - Sheng-Nan Zhang; Lin Huang; Rui-Jing Ma; Mei-Feng Yang; Ben-Fu Wei; Hong-Zhi Song; Heng-Shan Wang; Qin-Gang Tan (Natural Product Research, 2021)

An Integrated, Size-Structured Stock Assessment of Antarctic Krill, Euphausia superba - Rui Wang; Puqing Song; Yuan Li; Longshan Lin (Frontiers in Marine Science, 2021)
The Antarctic krill ( Euphausia superba ) fishery is the largest fishery in the Southern Ocean, and it has been operating for over 45 years. In the past decade, the spatial distribution of the krill fishery has focused on the Bransfield Strait off the Antarctic Peninsula (subarea 48.1). However, the high fishing effort and climate change have placed great pressure on krill resources in this region, and conservation concerns have been raised. Because aging krill is difficult and uncertain, we developed an integrated size-structured model to estimate the fishing mortality, recruitment and spawning biomass of krill. The results indicated that in 1992–2011, the average spawning biomass of krill ranged from 1.14 × 10 6 to 1.45 × 10 6 tons, the estimated biomass of the maximum sustainable yield (BMSY) ranged from 3.96 × 10 5 to 4.90 × 10 5 tons and the estimated average recruitment ranged from 2.3 × 10 12 to 5.03 × 10 12 individuals in the research area. We explored the effect of different data weighting schemes for the length data on the assessment output. However, our estimates also have uncertainties. In addition, an attempt was made to analyze the correlation between model-estimated recruitment and mature biomass with climate change. Future stock assessments of krill resources should be comprehensive and multimethod, and the management of krill resources should be based on science that considers the demand of fishing communities and ecosystem protection.

Fouling characteristics of cnidarians (Hydrozoa and Anthozoa) along the coast of China - Tao Yan; Mingqing Lin; Wenhao Cao; Shuaishuai Han; Xikun Song (Journal of Oceanology and Limnology, 2021)

A comparison of multiplatform wind products in the South China Sea during summer and autumn in 2019 - Yuxin Liu; Mingsen Lin; Xingwei Jiang; Xiujun Sun; Xiangzhou Song (Journal of Oceanology and Limnology, 2021)

Structure and variation of root-associated bacterial communities of Cyperus rotundus L. in the contaminated soils around Pb/Zn mine sites - Pin Gao; Benru Song; Rui Xu; Xiaoxu Sun; Hanzhi Lin; Fuqing Xu; Baoqin Li; Weimin Sun (Environmental Science and Pollution Research, 2021)

Streptomyces luteolifulvus sp. nov., a novel actinomycete isolated from soil in Nanjing, China - Shanshan Zhao; Ming Cheng; Congyu Lin; He Liu; Zhengran Wang; Kai Zhang; Simin Song; Qian Yang (Antonie van Leeuwenhoek, 2021)

Identification of plant materials containing ephedrine alkaloids based on DNA barcoding and TaqMan real-time PCR assay - Yaqin Zheng; Han Gao; Ming Song; Yunhan Lin; Jiajia Fan; Yaqin Zhang; Xia Liu (Acta Physiologiae Plantarum, 2021)
An intentional or inadvertent mixing of plant materials containing ephedrine alkaloids, especially Ephedra , is illegal. In order to better detect plant materials containing ephedrine alkaloids in export and smuggling, DNA barcoding combined with a TaqMan real-time PCR-based assay were used in this study. We collected 201 samples from 18 species belonging to four genera distributed in three families to amplify two barcoding markers, internal transcribed spacer 2 (ITS2) and psb A -trn H. 175 ITS2 sequences and 136 psb A- trn H sequences were obtained. Alignments and the neighbor-joining tree indicated that ITS2 showed a better discrimination of species than psb A -trn H. In addition, based on the sequence comparison of the ITS2 region from 18 species, three sets of primer/probes were designed using the real-time PCR assay platform. A sensitivity test showed the above primer/probe sets were specific and sensitive (as little as 0.0050 ng/μL target DNA) to identify species containing ephedrine alkaloids. Hence, the combination of novel DNA barcoding and the TaqMan real-time PCR-based technique are promising tools for the identification of plant materials containing ephedrine alkaloids. It is beneficial to standardize market circulation and detection of plant materials containing ephedrine alkaloids.

Characteristics of Ichthyoplankton Communities and Their Relationship With Environmental Factors Above the Ninety East Ridge, Eastern Indian Ocean - Liyan Zhang; Jing Zhang; Shigang Liu; Rui Wang; Jiali Xiang; Xing Miao; Ran Zhang; Puqing Song; Longshan Lin (Frontiers in Marine Science, 2021)
The Ninety East Ridge is a submarine north–south oriented volcanic ridge in the eastern Indian Ocean. Surface-layer ichthyoplankton collected in this area from September to October were identified by combined morphological and molecular (DNA barcoding) techniques, and their species composition, diversity, and abundance, and correlations with environmental variables were described. Collections comprised 109 larvae and 507 eggs, which were identified to 37 taxa in 7 orders, 20 families, and 27 genera, and were dominated by the order Perciformes and species Vinciguerria sp., Oxyporhamphus micropterus , and Decapterus macarellus . Species abundances at each station and of each species were relatively low, suggesting that this area or the time of sampling were not of major importance for fish spawning. Waters above Ninety East Ridge had lower species diversity but higher species richness than waters further offshore. A generalized additive model revealed that high abundance of ichthyoplanktonic taxa occurred in areas with low sea surface height and high sea surface salinity, temperature, and chlorophyll a concentration. Of these, sea surface height was most correlated with ichthyoplankton abundance. We provided baseline data on surface-dwelling ichthyoplankton communities in this area to aid in development of pelagic fishery resources in waters around the Ninety East Ridge.

Trophic Plasticity of Bombay Duck (Harpadon nehereus) in the South-Central East China Sea Based on Stable Isotope Evidence - Pu-Qing Song; Hu-Shun Zhang; Xin-Qing Zheng; Yuan-Yuan Li; Long-Shan Lin; Yuan Li (Frontiers in Marine Science, 2021)
High trophic plasticity is often invoked to explain the successful expansion of many aquatic species. Bombay duck (BD) outcompete other traditionally commercial fishes in the East China Sea (ECS) in recent years, displaying a continuous and sharp increase of catches, however, little is known whether the competition advantage of BD was related to its trophic plasticity. Using stable isotope analysis (SIA), we investigated the trophic ecology of BD in the south-central ECS in two periods. Significant differences in δ 13 C and δ 15 N values were found between sampling months and among body sizes. Modal (95% credibility limits) estimation showed that BD’s trophic position (TP) gradually increased from 3.56 (3.31–3.82) in G1 (120–150 mm for body size) to 4.09 (3.69–4.50) in G5 (241–270 mm) in November, and from 3.37 (2.92–3.88) in G2 (151–180 mm) to 3.66 (3.07–4.23) in G4 (211–240 mm) in April, respectively, suggesting obvious ontogenetic variation of δ 15 N and TP. More importantly, the TP of BD within the same body size showed wide amplitude, indicating BD possess high trophic plasticity, and can capture prey from low to high trophic levels. Further quantitative analysis based on the MixSIAR model showed that BD mainly fed on zooplankton and fish, but its feeding habit was characterized by the consumption of gradually reduced zooplankton and increased fish associated with increased body size. Interestingly, the fish’s contribution to BD showed obvious seasonal variation. It can be explained by varied food availability in ECS. Relatively low fish prey in April forced BD to adjust its diet, adding the ingestion of shrimps and cephalopods corresponding to temporal variations in food availability. The present study provides the evidence that high trophic plasticity exists in the feeding strategy of BD, which is reflected in the ability to adjust the feeding preference according to nutritional needs and food environmental changes; thus, it is competitively advantageous and may partly explain why BD is becoming the predominant species and displays an extensive distribution in the ECS.

Two new cephalochromin derivative from the Alternaria sp. ZG22 - Xin-Ming Song; Xue-Ming Zhou; Ya-Ling Li; Li-Bing Huang; Cai-Cui Chen; Yan Gao; Lin He; Xiao-qun Mao; Bing Chen; Jing-Wen Liu; Hui-Jie Liu; Xiao-Ping Song; et al. (Natural Product Research, 2021)

Functional analysis of indole 3-hexanoic acid as a novel auxin from Arabidopsis thaliana - Ping Song; Hui Xu; Jixiu Zhang; Huatao Chen; Li Li; Yana Qu; Feng Lin; Qun Zhang (Planta, 2021)

Alfalfa (Medicago sativa L.) MsCML46 gene encoding calmodulin-like protein confers tolerance to abiotic stress in tobacco - Binghao Du; Naiyu Chen; Lili Song; Dan Wang; Hongsheng Cai; Lin Yao; Xiuting Li; Changhong Guo (Plant Cell Reports, 2021)

Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1 - Guang-Tong Jiang; Lin Shao; Shuo Kong; Meng-Liu Zeng; Jing-Jing Cheng; Tao-Xiang Chen; Song Han; Jun Yin; Wan-Hong Liu; Xiao-Hua He; Yu-Min Liu; Lanzi Gongga; et al. (Neuroscience Bulletin, 2021)

Reservoir Characterization Using Multi-component Seismic Data in a Novel Hybrid Model Based on Clustering and Deep Neural Network - Jiuqiang Yang; Niantian Lin; Kai Zhang; Chong Zhang; Chao Fu; Gaopeng Tian; Cuiyu Song (Natural Resources Research, 2021)

A dynamical pathway bridging African biomass burning and Asian summer monsoon - Dianbin Cao; Tae-Won Park; Yongjia Song; Yuhang Wang; Zhenyu You; Yanluan Lin; Yi Deng (Climate Dynamics, 2021)

Sandaracinobacteroides hominis gen. nov., sp. nov., isolated from human skin - Ping-Hua Qu; Hai-Min Luo; Jun-Hui Feng; Song Li; Cha Chen; Lei Dong; Yu-Zhen Ming; Wen-Jun Li; Ying Lin (Archives of Microbiology, 2021)

Quercetin Attenuates High-Fat Diet-Induced Excessive Fat Deposition of Spotted Seabass (Lateolabrax maculatus) Through the Regulatory for Mitochondria and Endoplasmic Reticulum - Yan-Zou Dong; Tian Xia; Ji-Bin Lin; Ling Wang; Kai Song; Chun-Xiao Zhang (Frontiers in Marine Science, 2021)
This study aimed to investigate the effects of quercetin (QUE) on fat deposition and the underlying mechanism. Fish were fed four test diets: normal fat diet (NFD), high-fat diet (HFD), and HFD supplemented with 0.5 or 1.0 g/kg quercetin (QUE0.5 or QUE1.0). The results showed that HFD feeding resulted in poor growth and feed utilization while QUE treatment reversed this. The fat contents of serum and liver were increased by HFD and QUE supplementation significantly decreased fat content. Furthermore, gene expressions and ultrastructure observation showed that mitochondrial biogenesis and mitophagy were inhibited and endoplasmic reticulum stress (ERS) in the HFD group. QUE can activate the biogenesis and autophagy of mitochondria and suppress ERS, which is related to its fat-lowering effect.

A new monoterpene-lactone with neuroprotective activity from corn silk - Wei-Yu Zhou; Tian-Ming Lv; Zi-Lin Hou; Ming Bai; Bin Lin; Xiao-Xiao Huang; Shao-Jiang Song (Natural Product Research, 2021)

Extensional tectonics and North China Craton destruction: Insights from the magnetic susceptibility anisotropy (AMS) of granite and metamorphic core complex - Wei Lin; Jipei Zeng; Lingtong Meng; Huabiao Qiu; Wei Wei; Zhiheng Ren; Yang Chu; Shuangjian Li; Chao Song; Qincheng Wang (Science China Earth Sciences, 2021)

NRG1 accelerates the forgetting of fear memories and facilitates the induction of long-term depression in adult mice - Qianqian Cao; Yuan Wei; Jialin Deng; Junfeng Li; Yanhua Huang; Yuke Li; Ji-chun Zhang; Zili Zhang; Song Lin (Psychopharmacology, 2021)

The ATP Level in the mPFC Mediates the Antidepressant Effect of Calorie Restriction - Qian Wang; Ying Kong; Song Lin; Ding-Yu Wu; Jian Hu; Lang Huang; Wen-Si Zang; Xiao-Wen Li; Jian-Ming Yang; Tian-Ming Gao (Neuroscience Bulletin, 2021)

Effect of Fe–Mn–La-modified biochar composites on arsenic volatilization in flooded paddy soil - Lina Lin; Minling Gao; Xuewei Liu; Weiwen Qiu; Zhengguo Song (Environmental Science and Pollution Research, 2021)

Do fiscal decentralization and natural resources rent curb carbon emissions? Evidence from developed countries - Muhammad Tufail; Lin Song; Tomiwa Sunday Adebayo; Dervis Kirikkaleli; Suliman Khan (Environmental Science and Pollution Research, 2021)

High-throughput sequencing clarifies the spatial structures of microbial communities in cadmium-polluted rice soils - Li Song; Zhenzhi Pan; Yi Dai; Lin Chen; Li Zhang; Qilin Liao; Xiezhi Yu; Hongyan Guo; Guisheng Zhou (Environmental Science and Pollution Research, 2021)

Sphingobacterium rhinopitheci sp. Nov., isolated from the faeces of Rhinopithecus bieti in China - Xiu-Lin Han; Qiong Wang; Chen-Lu Zhang; Zhi-Qin Fang; Jian-Qiang Shen; Song Huang; Tao Lu (Archives of Microbiology, 2021)

Elevated pCO2 Impedes Succession of Phytoplankton Community From Diatoms to Dinoflagellates Along With Increased Abundance of Viruses and Bacteria - Ruiping Huang; Jiazhen Sun; Yunlan Yang; Xiaowen Jiang; Zhen Wang; Xue Song; Tifeng Wang; Di Zhang; He Li; Xiangqi Yi; Shouchang Chen; Nanou Bao; et al. (Frontiers in Marine Science, 2021)
Eutrophic coastal regions are highly productive and greatly influenced by human activities. Primary production supporting the coastal ecosystems is supposed to be affected by progressive ocean acidification driven by increasing CO 2 emissions. In order to investigate the effects of high p CO 2 (HC) on eutrophic plankton community structure and ecological functions, we employed 9 mesocosms and carried out an experiment under ambient (∼410 ppmv) and future high (1000 ppmv) atmospheric p CO 2 conditions, using in situ plankton community in Wuyuan Bay, East China Sea. Our results showed that HC along with natural seawater temperature rise significantly boosted biomass of diatoms with decreased abundance of dinoflagellates in the late stage of the experiment, demonstrating that HC repressed the succession from diatoms to dinoflagellates, a phenomenon observed during algal blooms in the East China Sea. HC did not significantly influence the primary production or biogenic silica contents of the phytoplankton assemblages. However, the HC treatments increased the abundance of viruses and heterotrophic bacteria, reflecting a refueling of nutrients for phytoplankton growth from virus-mediated cell lysis and bacterial degradation of organic matters. Conclusively, our results suggest that increasing CO 2 concentrations can modulate plankton structure including the succession of phytoplankton community and the abundance of viruses and bacteria in eutrophic coastal waters, which may lead to altered biogeochemical cycles of carbon and nutrients.

Assessment of the Nutritional Value of Cultured Sea Cucumber Apostichopus japonicus - Meng Li; Yue Gao; Yan-xia Qi; Zhi-yuan Song; Zhi-bo Li; Yan-tong Lin; Qian-cheng Zhao (Journal of Aquatic Food Product Technology, 2021)

Augmented BMP4 signal impairs tongue myogenesis - Jian Zhang; Chensheng Lin; Yingnan Song; Yanding Zhang; Jiang Chen (Journal of Molecular Histology, 2021)

Whole brain volume and cortical thickness abnormalities in Wilson’s disease: a clinical correlation study - Yukun Song; Lin Zou; Jing Zhao; Xiangxue Zhou; Yingqian Huang; Haishan Qiu; Haiwei Han; Zhiyun Yang; Xunhua Li; Xiaoying Tang; Jianping Chu (Brain Imaging and Behavior, 2021)

The Characteristic of Critical Genes in Neuroendocrine System and Their Regulation on Food Habit Transition and Metamorphosis of Veined Rapa Whelk Rapana venosa (Valenciennes, 1846) - Mei-Jie Yang; Jie Feng; Hao Song; Zheng-Lin Yu; Pu Shi; Jian Liang; Zhi Hu; Cong Zhou; Xiao-Lin Wang; Tao Zhang (Frontiers in Marine Science, 2021)
Metamorphosis is a critical developmental event in mollusks, and neuroendocrine system plays an essential role in this process. Rapana venosa is an economically important shellfish in China, but the artificial technology of R. venosa aquaculture is limited by metamorphosis. As a carnivorous gastropod, food habit transition makes the mechanism of R. venosa metamorphosis more complex. To investigate the changes in the neuroendocrine system and to reveal its role in regulating the food habit transition and metamorphosis of R. venosa , we cloned the cDNA sequences encoding 5-hydroxytryptamine receptor ( Rv-5HTR ), nitric oxide synthetase ( Rv-NOS ) and cholecystokinin receptor ( Rv-CCKR ), and investigated their expression by quantitative real-time PCR analysis, and explore the spatio-temporal changes of 5-HT protein expression using Immunohistochemical (IHC) analysis. The expression of the three geens was significantly increased in the early intramembrane veliger stage, which indicates that the three genes are related to the development of digestive system. Additionally, expression of the three genes was decreased after metamorphosis, while Rv-NOS and Rv-CCKR were increasingly expressed in competent larvae, which may help the larvae find suitable environments and promote digestive system development for metamorphosis, and the result of 5-HT IHC analysis also reflects the development of neuroendocrine system. Furthermore, results show that CCK can effect the expression of digestive enzyme, NOS and 5-HT receptor. Finally, based on the present results, we hypothesized that CCK and CCK receptor may be critical regulatory factors of food habit transition and metamorphosis. These results might provide information on the development of neuroendocrine system of R. venosa , and new insight into the regulation of the food habit transition and metamorphosis of gastropods.

Identification and phylogenetic analysis of five Crataegus species (Rosaceae) based on complete chloroplast genomes - Liwei Wu; Yingxian Cui; Qing Wang; Zhichao Xu; Yu Wang; Yulin Lin; Jingyuan Song; Hui Yao (Planta, 2021)

Anthracnose disease of Amomum villosum caused by Colletotrichum fructicola in China - Lisha Song; Wei Lin; Ni Jiang; Zhanjiang Zhang; Guiyu Tan; Shugen Wei (Journal of General Plant Pathology, 2021)

Glaciibacter flavus sp. nov., isolated from a lichen sample - De-Feng An; Long-Qian Jiang; Kun Zhang; Gui-Ding Li; Xin-Yu Wang; Ming-Guo Jiang; Lei Lang; Li-Song Wang; Johannes F. Imhoff; Cheng-Lin Jiang; Yi Jiang (Archives of Microbiology, 2021)

p -Terphenyls and actinomycins from a Streptomyces sp. associated with the larva of mud dauber wasp - Dan-Dan Lu; Jin-Wei Ren; Qian-Qian Du; Ya-Jie Song; Shi-Qi Lin; Xia Li; Er-Wei Li; Wei-Dong Xie (Natural Product Research, 2021)

Different posterior hippocampus and default mode network modulation in young APOE ε4 carriers: a functional connectome-informed phenotype longitudinal study - Li Juan Zheng; Li Lin; U. Joseph Schoepf; Akos Varga-Szemes; Rock H. Savage; Han Zhang; Yun Fei Wang; Xin Yuan Zhang; Song Luo; Ya Liu; Gui Fen Yang; Guang Ming Lu; et al. (Molecular Neurobiology, 2021)

Precise Control and Experimental Evaluation of a Novel Endoscopic Suturing Device for Large Perforations - Liaoyuan Ai; Chengli Song; Shuchen Ge; Shiju Yan; Lin Mao; Alfred Cuschieri (Journal of Medical and Biological Engineering, 2021)

Biosynthesis and preparation of phycoerythrobilin in recombinant Escherichia coli - Wenjun Li; Chengbo Ma; Baosheng Ge; Fan Zang; Song Qin; Jian Lin (Journal of Applied Phycology, 2021)

Effects of multi-phase inoculation on the fungal community related with the improvement of medicinal herbal residues composting - Xiao-Lin Lu; Hao Wu; Shi-Li Song; Hong-Yan Bai; Meng-Jun Tang; Fang-Ji Xu; Yan Ma; Chuan-Chao Dai; Yong Jia (Environmental Science and Pollution Research, 2021)

Detection of Human Sapoviruses in Sewage in China by Next Generation Sequencing - Ke Song; Xiaojuan Lin; Yao Liu; Feng Ji; Li Zhang; Peng Chen; Chenxu Zhao; Yanyan Song; Zexin Tao; Aiqiang Xu (Food and Environmental Virology, 2021)

Complete nucleotide sequence of a novel partitivirus from Brassica campestris L. ssp. chinensis - Liguang Tang; Liping Song; Chufa Lin; Bincai Wang; Jiazao Lin; Changbin Gao; Aihua Wang (Archives of Virology, 2021)

Development of a TaqMan loop-mediated isothermal amplification assay for the rapid detection of pigeon paramyxovirus type 1 - Ruiying Liang; Lin Liang; Xiaoxia Ren; Yaxiong Jia; Kun Han; Jingjie Zhao; Cuiping Song; Shangjin Cui (Archives of Virology, 2021)

Ring distribution patterns—diversification or speciation? Comparative phylogeography of two small mammals in the mountains surrounding the Sichuan Basin - Yanqun Wang; Anderson Feijó; Jilong Cheng; Lin Xia; Zhixin Wen; Deyan Ge; Jian Sun; Liang Lu; Song Li; Qisen Yang (Molecular Ecology, 2021)
Studying the genetic differentiation in a unique geographical area contributes to understanding the process of speciation. Here, we explore the spatial genetic structure and underlying formation mechanism of two congeneric small mammal species ( Apodemus draco and A. chevrieri ), which are mainly distributed in the mountains surrounding the lowland Sichuan Basin, southwest China. We applied a set of comparative phylogeographical analyses to determine their genetic diversification patterns, combining mitochondrial ( Cytb and COI ) and nuclear (microsatellite loci) markers, with dense sampling throughout the range (411 A . draco from 21 sites and 191 A . chevrieri from 22 sites). Moreover, we performed three complementary statistical methods to investigate the correlation between genotype and geographical and environmental components, and predicted the potential suitable distributional range under the present and historical climate conditions. Our results suggest that both species have experienced allopatric differentiation and admixture in historical periods, resulting in a ring‐shape diversification, under the barrier effect of the Sichuan Basin. We infer that the tectonic events of the Qinghai–Tibetan Plateau and climatic oscillations during the Quaternary played an important role on the genetic divergence of the two species by providing environmental heterogeneity and geographical variation. Our study reveals a case of two sympatric small mammals following a ring‐shaped diversification pattern and provides insight into the process of differentiation.

Identification of two UDP-glycosyltransferases involved in the main oleanane-type ginsenosides in Panax japonicus var. major - Jun-Rong Tang; Geng Chen; Ying-Chun Lu; Qing-Yan Tang; Wan-Ling Song; Yuan Lin; Ying Li; Su-Fang Peng; Sheng-Chao Yang; Guang-Hui Zhang; Bing Hao (Planta, 2021)

Estimate of nutrient sources and transport into Bohai Bay in China from a lower plain urban watershed using a SPARROW model - Zizhou Xu; Zhixin Ji; Bin Liang; Derui Song; Yong Lin; Jianguo Lin (Environmental Science and Pollution Research, 2021)

A novel negative-stranded RNA virus of the order Bunyavirales identified in Brassica campestris L. ssp. chinensis - Liguang Tang; Liping Song; Zhibiao Ye; Chufa Lin; Bincai Wang; Jiazao Lin; Changbin Gao; Aihua Wang (Archives of Virology, 2021)

Complete genome sequence of passiflora virus Y infecting passion fruit in China - Binghua Chen; Dali Wu; Hongying Zheng; Guangze Li; Yuhao Cao; Jianping Chen; Fei Yan; Xuemei Song; Lin Lin (Archives of Virology, 2021)

Effect of loading rate on the nonlinear elastic response of concrete - Xinyu Wang; Lin Song; Xicai Gao; Xu Chang (European Journal of Environmental and Civil Engineering, 2021)

Thermal study of the Duolong ore district in Tibet: implications for the uplift history of the Qiangtang terrane - Huanhuan Yang; Juxing Tang; Yang Song; John Dilles; Francis Sousa; Bin Lin (International Geology Review, 2021)

Application of a dissolved oxygen control strategy to increase the expression of Streptococcus suis glutamate dehydrogenase in Escherichia coli - Likun Cheng; Chunguang Zhao; Xiuyan Yang; Zheng Song; Chuwen Lin; Xiubao Zhao; Jinliang Wang; Jing Wang; Lei Wang; Xiaojing Xia; Zhiqiang Shen (World Journal of Microbiology and Biotechnology, 2021)

Non-linear relationships and interactions of meteorological factors on mumps in Jinan, China - Shaoqian Lin; Shiman Ruan; Xingyi Geng; Kaijun Song; Liangliang Cui; Xiaoxue Liu; Yingjian Zhang; Meng Cao; Ying Zhang (International Journal of Biometeorology, 2021)

Screening of binding proteins that interact with two components of the HOG MAPK pathway by the yeast two-hybrid method in Colletotrichum siamense - Xiaomiao Liao; Xiping Long; Qiguang He; Miao Song; Xiao Li; Wenbo Liu; Yu Zhang; Chunhua Lin; Weiguo Miao (European Journal of Plant Pathology, 2021)

Crenobacter intestini sp. nov., Isolated from the Intestinal Tract of Konosirus punctatus - Song-Biao Shi; Jia-Fa Wu; Li-Fang Yang; Ming-Guo Jiang; Cai-Mi Gao; Cheng-Lin Jiang; Yi Jiang (Current Microbiology, 2021)

Strategies to solve the reverse inference fallacy in future MRI studies of schizophrenia: a review - Chuanjun Zhuo; Gongying Li; Xiaodong Lin; Deguo Jiang; Yong Xu; Hongjun Tian; Wenqiang Wang; Xueqin Song (Brain Imaging and Behavior, 2021)
Few advances in schizophrenia research have been translated into clinical practice, despite 60 years of serum biomarkers studies and 50 years of genetic studies. During the last 30 years, neuroimaging studies on schizophrenia have gradually increased, partly due to the beautiful prospect that the pathophysiology of schizophrenia could be explained entirely by the Human Connectome Project (HCP). However, the fallacy of reverse inference has been a critical problem of the HCP. For this reason, there is a dire need for new strategies or research “bridges” to further schizophrenia at the biological level. To understand the importance of research “bridges,” it is vital to examine the strengths and weaknesses of the recent literature. Hence, in this review, our team has summarized the recent literature (1995–2018) about magnetic resonance imaging (MRI) of schizophrenia in terms of regional and global structural and functional alterations. We have also provided a new proposal that may supplement the HCP for studying schizophrenia. As postulated, despite the vast number of MRI studies in schizophrenia, the lack of homogeneity between the studies, along with the relatedness of schizophrenia with other neurological disorders, has hindered the study of schizophrenia. In addition, the reverse inference cannot be used to diagnose schizophrenia, further limiting the clinical impact of findings from medical imaging studies. We believe that multidisciplinary technologies may be used to develop research “bridges” to further investigate schizophrenia at the single neuron or neuron cluster levels. We have postulated about future strategies for overcoming the current limitations and establishing the research “bridges,” with an emphasis on multimodality imaging, molecular imaging, neuron cluster signals, single transmitter biomarkers, and nanotechnology. These research “bridges” may help solve the reverse inference fallacy and improve our understanding of schizophrenia for future studies.

Carbon isotope variations of modern soils in the eastern margin of the Tibetan Plateau and their controlling factors - Lin Qi; Yan-song Qiao; Zong-xiu Liu; Sha-sha Peng; Yu Cheng; Yan Wang; Xu-jiao Zhang; Ming-zhong Tian; Shuai-bin Yang; Wen-bin Bai (Journal of Mountain Science, 2021)

Adaptive Evolution of Chalcone Isomerase Superfamily in Fagaceae - Li-Mei Lin; Hong-Yu Guo; Xin Song; Duo-Duo Zhang; Yue-Hong Long; Zhao-Bin Xing (Biochemical Genetics, 2021)

Correction to: Effect of Surface Property on the Release and Oral Absorption of Solid Sirolimus-Containing Self-Microemulsifying Drug Delivery System - Xueting Zhang; Zhenzhen Chen; Chun Tao; Jing Zhang; Minxin Zhang; Jialiang Zhang; Zhihong Liu; Jiao Lin; Hang Xu; Qian Zhang; Hongtao Song (AAPS PharmSciTech, 2021)

Effect of Surface Property on the Release and Oral Absorption of Solid Sirolimus-Containing Self-microemulsifying Drug Delivery System - Xueting Zhang; Zhenzhen Chen; Chun Tao; Jing Zhang; Minxin Zhang; Jialiang Zhang; Zhihong Liu; Jiao Lin; Hang Xu; Qian Zhang; Hongtao Song (AAPS PharmSciTech, 2021)

Research on Accurate Prediction of the Container Ship Resistance by RBFNN and Other Machine Learning Algorithms - Yunfei Yang; Haiwen Tu; Lei Song; Lin Chen; De Xie; Jianglong Sun (Journal of Marine Science and Engineering, 2021)
Resistance is one of the important performance indicators of ships. In this paper, a prediction method based on the Radial Basis Function neural network (RBFNN) is proposed to predict the resistance of a 13500 transmission extension unit (13500TEU) container ship at different drafts. The predicted draft state in the known range is called interpolation prediction; otherwise, it is extrapolation prediction. First, ship features are extracted to make the resistance Rt prediction. The resistance prediction results show that the performance of the RBFNN is significantly better than the other four machine learning models, backpropagation neural network (BPNN), support vector machine (SVM), random forest (RF), and extreme gradient boosting (XGBoost). Then, the ship data is processed in a dimensionless manner, and the models mentioned above are used to predict the total resistance coefficient Ct of the container ship. The prediction results show that the RBFNN prediction model still performs well. Good results can be obtained by RBFNN in interpolation prediction, even when using part of dimensionless features. Finally, the accuracy of the prediction method based on RBFNN is greatly improved compared with the modified admiralty coefficient.

Effect of replacing inorganic trace minerals at lower organic levels on growth performance, blood parameters, antioxidant status, immune indexes, and fecal mineral excretion in weaned piglets - Wen-Fei Zhang; Min Tian; Jun-Shuai Song; Fang Chen; Gang Lin; Shi-Hai Zhang; Wu-Tai Guan (Tropical Animal Health and Production, 2021)

Dysfunction of chaperone-mediated autophagy in human diseases - Zhaozhong Liao; Bin Wang; Wenjing Liu; Qian Xu; Lin Hou; Jinlian Song; Qingming Guo; Ning Li (Molecular and Cellular Biochemistry, 2021)

RING-finger protein 5 promotes hepatocellular carcinoma progression and predicts poor prognosis - Yi Zhang; Jie Li; Huayang Chen; Changmao Zhang; Song You; Yue Zhao; Xiaoning Lin; Yaqi Yu; Fei Fang; Ting Fang; Xiaomin Wang (Human Cell, 2021)

Association of FMO3 rs1736557 polymorphism with clopidogrel response in Chinese patients with coronary artery disease - Kong-Xiang Zhu; Pei-Yuan Song; He-Li; Mu-Peng Li; Yin-xiao Du; Qi-lin Ma; Li-Ming Peng; Xiao-Ping Chen (European Journal of Clinical Pharmacology, 2021)

Polycyclic aromatic hydrocarbon and n-alkane pollution characteristics and structural and functional perturbations to the microbial community: a case-study of historically petroleum-contaminated soil - Jian Li; Ying Xu; Quanwei Song; Jie Yang; Lin Xie; Shihang Yu; Lei Zheng (Environmental Science and Pollution Research, 2021)

Effects of Grazing, Wind Erosion, and Dust Deposition on Plant Community Composition and Structure in a Temperate Steppe - Mengmei Zheng; Jian Song; Jingyi Ru; Zhenxing Zhou; Mingxing Zhong; Lin Jiang; Dafeng Hui; Shiqiang Wan (Ecosystems, 2021)

Identification of contaminants as members of the Bacillus pumilus group and analysis of contamination sources in the cultivation of Pleurotus geesteranus mushrooms - Na Lu; Wei-Dong Yuan; You-Liang Wu; Ji-Ling Song; Lin Ma; Wei-Ke Wang; Jing Yan; Zai-Ming Chen; Qing Chen (Journal of Plant Pathology, 2021)

Desorption of CO2, SO2, and NH3 in the vacuum evaporation of desulfurization wastewater - Guifang Chen; Xiaofei Sun; Yunqi Feng; Zhanlong Song; Lin Cui; Yanpeng Mao; Chunyuan Ma; Shouyan Chen (Environmental Science and Pollution Research, 2021)

Paracoccus lichenicola sp. nov., Isolated from Lichen - Lei Lang; De-Feng An; Long-Qian Jiang; Gui-Ding Li; Li-Song Wang; Xin-Yu Wang; Qin-Yuan Li; Cheng-Lin Jiang; Yi Jiang (Current Microbiology, 2021)

18 Additional Amino Acids of the Signal Peptide of the Bombyx mori Nucleopolyhedrovirus GP64 Activates Immunoglobulin Binding Protein (BiP) Expression by RNA-seq Analysis - Na Liu; Jinshan Huang; Lin Liu; Frank Boadi; Yanhui Song; Zhongjian Guo; Xingjia Shen; Bifang Hao (Current Microbiology, 2021)

Associations of Serum Selenium Levels in the First Trimester of Pregnancy with the Risk of Gestational Diabetes Mellitus and Preterm Birth: a Preliminary Cohort Study - Peng Ju Liu; Aimin Yao; Liangkun Ma; Xiao Yan Chen; Song Lin Yu; Yanping Liu; Yi Xuan Hou (Biological Trace Element Research, 2021)

Paleoglacial and paleoclimate reconstructions during the global Last Glacial Maximum in the Longriba area, eastern Tibetan Plateau - Wei-lin Yang; Ye-song Han; Xu Peng; Ze-ze Ran; Qing Liu; Geng-nian Liu (Journal of Mountain Science, 2021)

Seasonal analysis of artificial oyster reef ecosystems: implications for sustainable fisheries management - Min Xu; Xin yuan Yang; Xiao jing Song; Kai da Xu; Lin lin Yang (Aquaculture International, 2021)

CAS-ESM2.0 Model Datasets for the CMIP6 Flux-Anomaly-Forced Model Intercomparison Project (FAFMIP) - Jiangbo Jin; He Zhang; Xiao Dong; Hailong Liu; Minghua Zhang; Xin Gao; Juanxiong He; Zhaoyang Chai; Qingcun Zeng; Guangqing Zhou; Zhaohui Lin; Yi Yu; et al. (Advances in Atmospheric Sciences, 2021)
The second version of the Chinese Academy of Sciences Earth System Model (CAS-ESM2.0) is participating in the Flux-Anomaly-Forced Model Intercomparison Project (FAFMIP) experiments in phase 6 of the Coupled Model Intercomparison Project (CMIP6). The purpose of FAFMIP is to understand and reduce the uncertainty of ocean climate changes in response to increased CO 2 forcing in atmosphere-ocean general circulation models (AOGCMs), including the simulations of ocean heat content (OHC) change, ocean circulation change, and sea level rise due to thermal expansion. FAFMIP experiments (including faf-heat, faf-stress, faf-water, faf-all, faf-passiveheat, faf-heat-NA50pct and faf-heat-NA0ct) have been conducted. All of the experiments were integrated over a 70-year period and the corresponding data have been uploaded to the Earth System Grid Federation data server for CMIP6 users to download. This paper describes the experimental design and model datasets and evaluates the preliminary results of CAS-ESM2.0 simulations of ocean climate changes in the FAFMIP experiments. The simulations of the changes in global ocean temperature, Atlantic Meridional Overturning Circulation (AMOC), OHC., and dynamic sea level (DSL), are all reasonably reproduced.

CAS-ESM2.0 Model Datasets for the CMIP6 Ocean Model Intercomparison Project Phase 1 (OMIP1) - Xiao Dong; Jiangbo Jin; Hailong Liu; He Zhang; Minghua Zhang; Pengfei Lin; Qingcun Zeng; Guangqing Zhou; Yongqiang Yu; Mirong Song; Zhaohui Lin; Ruxu Lian; et al. (Advances in Atmospheric Sciences, 2021)
As a member of the Chinese modeling groups, the coupled ocean-ice component of the Chinese Academy of Sciences’ Earth System Model, version 2.0 (CAS-ESM2.0), is taking part in the Ocean Model Intercomparison Project Phase 1 (OMIP1) experiment of phase 6 of the Coupled Model Intercomparison Project (CMIP6). The simulation was conducted, and monthly outputs have been published on the ESGF (Earth System Grid Federation) data server. In this paper, the experimental dataset is introduced, and the preliminary performances of the ocean model in simulating the global ocean temperature, salinity, sea surface temperature, sea surface salinity, sea surface height, sea ice, and Atlantic Meridional Overturning Circulation (AMOC) are evaluated. The results show that the model is at quasi-equilibrium during the integration of 372 years, and performances of the model are reasonable compared with observations. This dataset is ready to be downloaded and used by the community in related research, e.g., multi-ocean-sea-ice model performance evaluation and interannual variation in oceans driven by prescribed atmospheric forcing.

The involvement of α‐proteobacteria Phenylobacterium in maintaining the dominance of toxic Microcystis blooms in Lake Taihu, China - Jun Zuo; Lili Hu; Wei Shen; Jiaying Zeng; Lin Li; Lirong Song; Nanqin Gan (Environmental Microbiology, 2021)
Summary Lake Taihu in China has suffered serious harmful cyanobacterial blooms for decades. The algal blooms threaten the ecological sustainability, drinking water safety, and human health. Although the roles of abiotic factors (such as water temperature and nutrient loading) in promoting Microcystis blooms have been well studied, the importance of biotic factors (e.g. bacterial community) in promoting and meditating Microcystis blooms remains unclear. In this study, we investigated the ecological dynamics of bacterial community, the ratio of toxic Microcystis , as well as microcystin in Lake Taihu. High‐throughput 16S rRNA sequencing and principal component analysis (PCA) revealed that the bacteria community compositions (BCCs) clustered into three groups, the partitioning of which corresponded to that of groups according to the toxic profiles (the ratio of toxic Microcystis to total Microcystis , and the microcystin concentrations) of the samples. Further Spearman's correlation network showed that the α‐proteobacteria Phenylobacterium strongly positively correlated with the toxic profiles. Subsequent laboratory chemostats experiments demonstrated that three Phenylobacterium strains promoted the dominance of the toxic Microcystis aeruginosa PCC7806 when co‐culturing with the non‐toxic PCC7806 mcyB − mutant. Taken together, our data suggested that the α‐proteobacteria Phenylobacterium may play a vital role in the maintenance of toxic Microcystis dominance in Lake Taihu.

Mechanisms of high-frequency dinoflagellate blooms of Scrippsiella trochoidea in Daya Bay, South China Sea - Yuan Tian; Simin Hu; Xianzhi Lin; Hui Huang; Xingyu Song; Yan Yan; Xuedong Xie; Tao Li; Sheng Liu (Journal of Oceanology and Limnology, 2021)

Ca2+/Calmodulin-NOS/NO-TNFs Pathway Hallmarks the Inflammation Response of Oyster During Aerial Exposure - Hao Chen; Lusheng Xin; Lin Wang; Huan Zhang; Rui Liu; Hao Wang; Xue Qiao; Lingling Wang; Linsheng Song (Frontiers in Marine Science, 2021)
Aerial exposure (emersion) due to the periodical ebb and flow of tides is a major stressor for intertidal organisms and a key environmental factor in shaping their local communities. Oysters are among the most emersion-tolerant mollusk species and can survive for several days under aerial exposure. Noticeably, overwhelming inflammation responses could occur during the emersion stress. However, mechanisms beneath the activation and modulation of emersion-induced inflammation response have remained largely unknown. Ca 2+ is an important intracellular second messenger that plays indispensable roles in inflammation response by cooperation with calmodulin (CaM) genes. Here, we showed that intracellular Ca 2+ accumulates rapidly in oyster hemocytes during emersion stress along with the changes in the protein levels of three CaM genes, which function as intracellular sensors of Ca 2+ . As downstream effector of Ca 2+ /CaM complex, nitric oxide synthase (NOS) activity in hemocytes was enhanced during the emersion stress, facilitating a greater production of nitrite oxide (NO). Augmentation of NO concentration was associated with the increased mRNA expression levels of two oyster cytokines (CgTNFs) during aerial exposure. The robust accumulation of cytokines and severe injury of tissues in oysters have been regarded as potential cause and marker of their death in prolonged emersion stress. Here, both the expression levels of CgTNFs and the tissue injuries of oysters were attenuated when Ca 2+ /CaM complex or NOS activity were repressed in vivo during the emersion stress. These findings indicate that Ca 2+ /CaM-NOS/NO-CgTNFs pathway is critically involved in the emersion-induced inflammation response in oysters and plays a role in the resistance against long-term aerial exposure.

Identification of 5S and 45S rDNA sites in Chrysanthemum species by using oligonucleotide fluorescence in situ hybridization (Oligo-FISH) - Jun He; Sisi Lin; Zhongyu Yu; Aiping Song; Zhiyong Guan; Weimin Fang; Sumei Chen; Fei Zhang; Jiafu Jiang; Fadi Chen; Haibin Wang (Molecular Biology Reports, 2021)

Production of functional human nerve growth factor from the submandibular glands of mice using a CRISPR/Cas9 genome editing system - Yi Gu; Hui Cao; Fei Li; Jianli Yu; Rui Nian; Dongxiao Feng; Jingtao Lin; Haipeng Song; Wenshuai Liu (World Journal of Microbiology and Biotechnology, 2020)

Quantitative Determination of Glymphatic Flow Using Spectrophotofluorometry - Yu Zhang; Jian Song; Xu-Zhong He; Jian Xiong; Rong Xue; Jia-Hao Ge; Shi-Yu Lu; Die Hu; Guo-Xing Zhang; Guang-Yin Xu; Lin-Hui Wang (Neuroscience Bulletin, 2020)

Rockburst Risk Analysis During High-Hard Roof Breaking in Deep Mines - Qiming Zhang; Enyuan Wang; Xiaojun Feng; Yue Niu; Muhammad Ali; Song Lin; Hao Wang (Natural Resources Research, 2020)

Enhancing the production of a marine diatom (Skeletonema costatum) with low-frequency ultrasonic irradiation - Rediat Abate; Shuang Song; Vishal Patil; Changping Chen; Junrong Liang; Lin Sun; Xuesong Li; Bangqin Huang; Yahui Gao (Journal of Applied Phycology, 2020)

An allotriploid hybrid developed from a female 2n gamete was obtained from Eriobotrya japonica (Thunb.) Lindl × E. deflexa (Hemsl.) Nakai - Yanjuan Song; Jiangbo Dang; Weiwei Chen; Guo Wen; Qiao He; Xiaolin Li; Shoukai Lin; Guolu Liang; Qigao Guo (Euphytica, 2020)

Using sowing date management to promote micronutrient quality and alleviate cadmium accumulation in rice grains - Lin-lin Shi; Ming-xing Shen; Hong-jun Wu; Chang-ying Lu; Li-juan Mei; Xin-lian Zhu; Hai-hou Wang; Yun-Sheng Song (Cereal Research Communications, 2020)

Altered properties of brain white matter structural networks in patients with nasopharyngeal carcinoma after radiotherapy - Qinyuan Chen; Xiaofei Lv; Shufei Zhang; Jiabao Lin; Jie Song; Bolin Cao; Yihe Weng; Li Li; Ruiwang Huang (Brain Imaging and Behavior, 2020)

Greater promotion of DNRA rates and nrfA gene transcriptional activity by straw incorporation in alkaline than in acidic paddy soils - Ren Bai; Yun-Ting Fang; Liu-Ying Mo; Ju-Pei Shen; Lin-Lin Song; Ya-Qi Wang; Li-Mei Zhang; Ji-Zheng He (Soil Ecology Letters, 2020)

Nuclear Factor-κB Pathway Mediates the Molecular Pathogenesis of LMNA-Related Muscular Dystrophies - Yanbin Fan; Dandan Tan; Xu Zhang; Danyu Song; Xingzhi Chang; Shuang Wang; Hui Yan; Lin Ge; Haipo Yang; Carsten Bönnemann; Jingying Liu; Suxia Wang; et al. (Biochemical Genetics, 2020)

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales - Jens H. Kuhn; Scott Adkins; Daniela Alioto; Sergey V. Alkhovsky; Gaya K. Amarasinghe; Simon J. Anthony; Tatjana Avšič-Županc; María A. Ayllón; Justin Bahl; Anne Balkema-Buschmann; Matthew J. Ballinger; Tomáš Bartonička; et al. (Archives of Virology, 2020)

Two new sesquiterpenoid glycosides from the stems of Zanthoxylum armatum DC - Ya-Lin Liu; Liang-Liang Gao; Tong-Tong Song; Tao Guo; Jun Chang (Natural Product Research, 2020)

Divergence in flowering time is a major component contributing to reproductive isolation between two wild rice species (Oryza rufipogon and O. nivara) - Xun Xu; Qing-Lin Meng; Mu-Fan Geng; Ning-Ning Ren; Lian Zhou; Yu-Su Du; Zhe Cai; Mei-Xia Wang; Xin Wang; Xiu-Hua Wang; Jing-Dan Han; Shuai Jiang; et al. (Science China Life Sciences, 2020)

Illumina sequencing revealed roles of microRNAs in different aluminum tolerance of two citrus species - Yang-Fei Zhou; Yan-Yu Wang; Wei-Wei Chen; Li-Song Chen; Lin-Tong Yang (Physiology and Molecular Biology of Plants, 2020)

Mechanism of contractile dysfunction induced by serotonin in coronary artery in spontaneously hypertensive rats - Hao Wang; Xiao-Yan Gao; Fang Rao; Hui Yang; Zhao-Yu Wang; Lin Liu; Su-Juan Kuang; Qi Wu; Chun-Yu Deng; Jing-Song Xu (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

MicroRNA-761 modulates foam cell formation and inflammation through autophagy in the progression of atherosclerosis - Chao Wang; Wei Yang; Xiaofei Liang; Wei Song; Jing Lin; Yan Sun; Xiuru Guan (Molecular and Cellular Biochemistry, 2020)

Mitigating arsenic accumulation in rice (Oryza sativa L.) using Fe-Mn-La-impregnated biochar composites in arsenic-contaminated paddy soil - Lina Lin; Minling Gao; Zhengguo Song; Haiyan Mu (Environmental Science and Pollution Research, 2020)

Optimization for allitol production from d-glucose by using immobilized glucose isomerase and recombinant E. coli expressing d-psicose-3-epimerase, ribitol dehydrogenase and formate dehydrogenase - Xin Wen; Huibin Lin; Yilin Ren; Can Li; Chengjia Zhang; Xin Song; Jianqun Lin; Jianqiang Lin (Biotechnology Letters, 2020)

Mitigating Climate Change for Sugarcane Improvement: Role of Silicon in Alleviating Abiotic Stresses - Krishan K. Verma; Pratiksha Singh; Xiu-Peng Song; Mukesh Kumar Malviya; Rajesh Kumar Singh; Gan-Lin Chen; Sushil Solomon; Yang-Rui Li (Sugar Tech, 2020)

Mu-Opioid Receptors Expressed in Glutamatergic Neurons are Essential for Morphine Withdrawal - Xin-Yan Zhang; Qing Li; Ye Dong; Wei Yan; Kun Song; Yong-Qin Lin; Yan-Gang Sun (Neuroscience Bulletin, 2020)

Identification of Prognostic Signatures of Alternative Splicing in Glioma - Yu Zeng; Peidong Zhang; Xizhao Wang; Ke Wang; Mingfeng Zhou; Hao Long; Jie Lin; Zhiyong Wu; Liang Gao; Ye Song (Journal of Molecular Neuroscience, 2020)

Preparation of high-purity R-phycoerythrin and R-phycocyanin from Pyropia yezoensis in membrane chromatography - Fan Zang; Song Qin; Chengbo Ma; Wenjun Li; Jian Lin (Journal of Applied Phycology, 2020)

Roles of MicroRNA-122 in Cardiovascular Fibrosis and Related Diseases - Ying Liu; Jia-Wei Song; Jian-Yu Lin; Ran Miao; Jiu-Chang Zhong (Cardiovascular Toxicology, 2020)

CAS-FGOALS Datasets for the Two Interglacial Epochs of the Holocene and the Last Interglacial in PMIP4 - Weipeng Zheng; Yongqiang Yu; Yihua Luan; Shuwen Zhao; Bian He; Li Dong; Mirong Song; Pengfei Lin; Hailong Liu (Advances in Atmospheric Sciences, 2020)
Two versions of the Chinese Academy of Sciences Flexible Global Ocean-Atmosphere-Land System model (CAS-FGOALS), version f3-L and g3, are used to simulate the two interglacial epochs of the mid-Holocene and the Last Interglacial in phase 4 of the Paleoclimate Modelling Intercomparison Project (PMIP4), which aims to study the impact of changes in orbital parameters on the Earth’s climate. Following the PMIP4 experimental protocols, four simulations for the mid-Holocene and two simulations for the Last Interglacial have been completed, and all the data, including monthly and daily outputs for the atmospheric, oceanic, land and sea-ice components, have been released on the Earth System Grid Federation (ESGF) node. These datasets contribute to PMIP4 and CMIP6 (phase 6 of the Coupled Model Intercomparison Project) by providing the variables necessary for the two interglacial periods. In this paper, the basic information of the CAS-FGOALS models and the protocols for the two interglacials are briefly described, and the datasets are validated using proxy records. Results suggest that the CAS-FGOALS models capture the large-scale changes in the climate system in response to changes in solar insolation during the interglacial epochs, including warming in mid-to-high latitudes, changes in the hydrological cycle, the seasonal variation in the extent of sea ice, and the damping of interannual variabilities in the tropical Pacific. Meanwhile, disagreements within and between the models and the proxy data are also presented. These datasets will help the modeling and the proxy data communities with a better understanding of model performance and biases in paleoclimate simulations.

Schizandrol A protects against Aβ1–42-induced autophagy via activation of PI3K/AKT/mTOR pathway in SH-SY5Y cells and primary hippocampal neurons - Lin Song; Lifen Yao; Limei Zhang; Zhongyuan Piao; Yichan Lu (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

Gastrointestinal involvement of COVID-19 and potential faecal transmission of SARS-CoV-2 - Min Song; Zong-lin Li; Ye-jiang Zhou; Gang Tian; Ting Ye; Zhang-rui Zeng; Jian Deng; Hong Wan; Qing Li; Jin-bo Liu (Journal of Zhejiang University-SCIENCE B, 2020)

Gene UCHL1 expresses specifically in mouse uterine decidual cells in response to estrogen - Lishuang Hao; Di Song; Mengfei Zhuang; Yan Shi; Lin Yu; Yaping He; Jian Wang; Tingting Zhang; Zhaogui Sun (Histochemistry and Cell Biology, 2020)

North Pacific storm track response to the mesoscale SST in a global high-resolution atmospheric model - Chao Zhang; Hailong Liu; Jinbo Xie; Pengfei Lin; Chongyin Li; Qian Yang; Jie Song (Climate Dynamics, 2020)

Seasonal Sea Surface Temperature Variability over Tropical Indo-Pacific Region Simulated by FIO-ESM Model Under Global Warming - Xinyou Zhang; Lin Liu; Yajuan Song (Pure and Applied Geophysics, 2020)