A global initiative for ecological and evolutionary hologenomics - Aoife Leonard; Javier Abalos; Titus Adhola; Windsor Aguirre; Ostaizka Aizpurua; Shahzad Ali; Franco Andreone; Fabien Aubret; Hefer D. Ávila-Palma; Lizbeth Fabiola Bautista Alcantara; Juan F. Beltrán; Rachel Berg; et al. (Trends in Ecology & Evolution, 2024)

Prenatal exposure to polycyclic aromatic hydrocarbons and executive functions at school age: Results from a combined cohort study - Yu Ni; Adam A. Szpiro; Christine T. Loftus; Tomomi Workman; Alexis Sullivan; Erin R. Wallace; Anne M. Riederer; Drew B. Day; Laura E. Murphy; Ruby H.N. Nguyen; Sheela Sathyanarayana; Emily S. Barrett; et al. (International Journal of Hygiene and Environmental Health, 2024)

Are the symbiont faunas of the venomous echinoids Toxopneustes pileolus and Tripneustes gratilla (Echinoidea, Toxopneustidae) similar? - P. Yu. Dgebuadze; O. A. Bratova; V. N. Ivanenko; N. T. H. Thanh; T. A. Britayev (Symbiosis, 2024)

Gastroprotective Effect of GABA in Metabolic Stress - N. S. Tropskaya; Yu. V. Gurman; T. S. Popova; A. A. Kanibolotsky (Bulletin of Experimental Biology and Medicine, 2024)

Extension of the soil monitoring network via tea bag initiatives: A 3000 km latitudinal gradient in European Russia - K. Ivashchenko; O. Gavrichkova; M. Korneykova; V. Vasenev; N. Salnik; N. Saltan; D. Sarzhanov; E. Babenko; S. Urabova; M. Slukovskaya; M. Zavodskikh; S. Gorbov; et al. (Science of The Total Environment, 2024)

Climate-regulation of organic carbon export in erosive mountain settings: A case study from Taiwan since the last glacial maximum - Li-Wei Zheng; Robert G. Hilton; Yuan-Pin Chang; Rick J. Yang; Xiaodong Ding; Xufeng Zheng; Tsung-Yu Lee; Hsi-Jih Lu; Jung-Tai Lu; Yu-Shih Lin; James T. Liu; Shuh-Ji Kao (Quaternary Science Reviews, 2024)

Experimental and theoretical constraints on lithium isotope fractionation during brine evaporation and halite precipitation - Yongjie Lin; Marcello Merli; Paolo Censi; Simon A.T. Redfern; Yue Zhao; Qing-Zhu Yin; Mianping Zheng; Xudong Yu; Yongsheng Zhang; William J. Knapp; Edward T. Tipper (Geochimica et Cosmochimica Acta, 2024)

Interaction of Cortricotropin-Releasing Hormone and Capsaicin-Sensitive Afferent Neurons in Gastroprotection - N. I. Yarushkina; T. T. Podvigina; O. Yu. Morozova; L. P. Filaretova (Neuroscience and Behavioral Physiology, 2024)

Redox-Active Compounds in the Therapy of Drug-Resistant Murine Leukemia P388 Strains - T. A. Raevskaya; Yu. V. Soldatova; S. A. Goncharova; I. I. Faingold (Bulletin of Experimental Biology and Medicine, 2024)

Hypochlorous Acid-Modified Serum Albumin Causes NETosis in the Whole Blood Ex Vivo and in Isolated Neutrophils - L. Yu. Basyreva; E. V. Shmeleva; T. V. Vakhrusheva; I. V. Gorudko; D. V. Grigorieva; V. A. Kostevich; N. P. Gorbunov; A. V. Sokolov; S. A. Gusev; O. M. Panasenko; V. I. Sergienko (Bulletin of Experimental Biology and Medicine, 2024)

Correction: Spontaneous mutations and mutational responses to penicillin treatment in the bacterial pathogen Streptococcus pneumoniae D39 - Wanyue Jiang; Tongtong Lin; Jiao Pan; Caitlyn E. Rivera; Clayton Tincher; Yaohai Wang; Yu Zhang; Xiang Gao; Yan Wang; Ho-Ching T. Tsui; Malcolm E. Winkler; Michael Lynch; et al. (Marine Life Science & Technology, 2024)

Tracking diarrhea viruses and mpox virus using the wastewater surveillance network in Hong Kong - Xiawan Zheng; Keyue Zhao; Bingjie Xue; Yu Deng; Xiaoqing Xu; Weifu Yan; Chao Rong; Kathy Leung; Joseph T. Wu; Gabriel M. Leung; Malik Peiris; Leo L.M. Poon; et al. (Water Research, 2024)

To and fro in the archipelago: Repeated inter-island dispersal and New Guinea’s orogeny affect diversification of Delias, the world’s largest butterfly genus - Weijun Liang; Renato Nunes; Jing V. Leong; Ana Paula S. Carvalho; Chris J. Müller; Michael F. Braby; Olivier Pequin; Sugihiko Hoshizaki; Sadaharu Morinaka; Djunijanti Peggie; Jade Aster T. Badon; Alma B. Mohagan; et al. (Molecular Phylogenetics and Evolution, 2024)

Associations of prenatal ambient air pollution exposures with asthma in middle childhood - Marnie F. Hazlehurst; Kecia N. Carroll; Paul E. Moore; Adam A. Szpiro; Margaret A. Adgent; Logan C. Dearborn; Allison R. Sherris; Christine T. Loftus; Yu Ni; Qi Zhao; Emily S. Barrett; Ruby H.N. Nguyen; et al. (International Journal of Hygiene and Environmental Health, 2024)

Tuning combustion and energy in hydroxylammonium nitrate (HAN)-based electrically controlled solid propellant - Feng Li; Zhiwen Wang; Qianyi Zhang; Zeyu Cheng; Yixin Yu; Ruiqi Shen; Yinghua Ye; Luigi T. DeLuca; Wei Zhang (Chemical Engineering Journal, 2024)

Assessment of the Acute Toxicity of Chlorophyllin and Trolox for the Possibility of Studying Their Radioprotective Properties - L. A. Romodin; O. V. Nikitenko; T. M. Bychkova; Yu. A. Zrilova; E. D. Rodionova; D. A. Bocharov (Bulletin of Experimental Biology and Medicine, 2024)

The Role of Smad3 in the Realization of the Growth Potential of Different Types of Neural Progenitor Cells and the Secretory Function of Neuroglia - G. N. Zyuz’kov; L. A. Miroshnichenko; T. Yu. Polyakova; E. V. Simanina; A. V. Chaikovsky; V. I. Agafonov; L. A. Stavrova; E. V. Udut; A. A. Churin; V. V. Zhdanov (Bulletin of Experimental Biology and Medicine, 2024)

Spontaneous mutations and mutational responses to penicillin treatment in the bacterial pathogen Streptococcus pneumoniae D39 - Wanyue Jiang; Tongtong Lin; Jiao Pan; Caitlyn E. Rivera; Clayton Tincher; Yaohai Wang; Yu Zhang; Xiang Gao; Yan Wang; Ho-Ching T. Tsui; Malcolm E. Winkler; Michael Lynch; et al. (Marine Life Science & Technology, 2024)
Bacteria with functional DNA repair systems are expected to have low mutation rates due to strong natural selection for genomic stability. However, our study of the wild-type Streptococcus pneumoniae D39, a pathogen responsible for many common diseases, revealed a high spontaneous mutation rate of 0.02 per genome per cell division in mutation-accumulation (MA) lines. This rate is orders of magnitude higher than that of other non-mutator bacteria and is characterized by a high mutation bias in the A/T direction. The high mutation rate may have resulted from a reduction in the overall efficiency of selection, conferred by the tiny effective population size in nature. In line with this, S. pneumoniae D39 also exhibited the lowest DNA mismatch-repair (MMR) efficiency among bacteria. Treatment with the antibiotic penicillin did not elevate the mutation rate, as penicillin did not induce DNA damage and S. pneumoniae lacks a stress response pathway. Our findings suggested that the MA results are applicable to within-host scenarios and provide insights into pathogen evolution.

Suprastin (Chloropyramine) Causes Proarrhythmic Deterioration of Excitation Conduction, Depolarization and Potentiates Adrenergic Automaticity in the Pulmonary Veins Myocardium - Yu. V. Egorov; T. S. Filatova; A. A. Abramov; V. S. Kuzmin (Bulletin of Experimental Biology and Medicine, 2024)

Precipitation uncertainty estimation and rainfall-runoff model calibration using iterative ensemble smoothers - Davide Zoccatelli; Daniel B. Wright; Jeremy T. White; Michael N. Fienen; Guo Yu (Advances in Water Resources, 2024)

Sitagliptin elevates plasma and CSF incretin levels following oral administration to nonhuman primates: relevance for neurodegenerative disorders - Yazhou Li; Kelli L. Vaughan; Yun Wang; Seong-Jin Yu; Eun-Kyung Bae; Ian A. Tamargo; Katherine O. Kopp; David Tweedie; Cheng-Chuan Chiang; Keith T. Schmidt; Debomoy K. Lahiri; Michael A. Tones; et al. (GeroScience, 2024)
The endogenous incretins glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) possess neurotrophic, neuroprotective, and anti-neuroinflammatory actions. The dipeptidyl peptidase 4 (DPP-4) inhibitor sitagliptin reduces degradation of endogenous GLP-1 and GIP, and, thereby, extends the circulation of these protective peptides. The current nonhuman primate (NHP) study evaluates whether human translational sitagliptin doses can elevate systemic and central nervous system (CNS) levels of GLP-1/GIP in naive, non-lesioned NHPs, in line with our prior rodent studies that demonstrated sitagliptin efficacy in preclinical models of Parkinson’s disease (PD). PD is an age-associated neurodegenerative disorder whose current treatment is inadequate. Repositioning of the well-tolerated and efficacious diabetes drug sitagliptin provides a rapid approach to add to the therapeutic armamentarium for PD. The pharmacokinetics and pharmacodynamics of 3 oral sitagliptin doses (5, 20, and 100 mg/kg), equivalent to the routine clinical dose, a tolerated higher clinical dose and a maximal dose in monkey, were evaluated. Peak plasma sitagliptin levels were aligned both with prior reports in humans administered equivalent doses and with those in rodents demonstrating reduction of PD associated neurodegeneration. Although CNS uptake of sitagliptin was low (cerebrospinal fluid (CSF)/plasma ratio 0.01), both plasma and CSF concentrations of GLP-1/GIP were elevated in line with efficacy in prior rodent PD studies. Additional cellular studies evaluating human SH-SY5Y and primary rat ventral mesencephalic cultures challenged with 6-hydroxydopamine, established cellular models of PD, demonstrated that joint treatment with GLP-1 + GIP mitigated cell death, particularly when combined with DPP-4 inhibition to maintain incretin levels. In conclusion, this study provides a supportive translational step towards the clinical evaluation of sitagliptin in PD and other neurodegenerative disorders for which aging, similarly, is the greatest risk factor.

Effects of lipid extraction on stable isotope ratios of carbon and nitrogen in muscles of freshwater fish - Elena S. Ivanova; Maria A. Belova; Olga Yu. Rumiantseva; Alena A. Zudilova; Dmitry S. Kopylov; Michael Y. Borisov; Viktor T. Komov (Isotopes in Environmental and Health Studies, 2024)

Detrital U Pb zircon geochronology, zircon Lu Hf and Sr Nd isotopic signatures of the Lopingian volcanic-ash-derived Nb-Zr-REY-Ga mineralized horizons from eastern Yunnan, SW China - Ning Wang; Shifeng Dai; Victor P. Nechaev; David French; Ian T. Graham; Xiaolin Song; Igor Yu. Chekryzhov; Irina A. Tarasenko; Sergey Y. Budnitskiy (Lithos, 2024)

Compressive behavior of FRP-confined normal concrete or seawater sea-sand concrete containing FRP-bar recycled coarse aggregates - Z.Y. Gao; S.S. Zhang; Guan Lin; T. Yu; X.F. Nie (Engineering Structures, 2024)

Hostility as a Manifestation of Attachment Disorders in Depression - S. N. Enikolopov; O. Yu. Vorontsova; T. I. Medvedeva; O. M. Boyko; I. V. Oleichik (Neuroscience and Behavioral Physiology, 2024)

Radioprotective Properties of Riboxin (Inosine) and Indralin under External Irradiation - L. A. Romodin; O. V. Nikitenko; T. M. Bychkova; Yu. A. Zrilova; E. D. Rodionova; D. A. Bocharov (Bulletin of Experimental Biology and Medicine, 2024)

Features of Intracellular Signal Transduction in Neural Stem Cells under the Influence of Alkaloid Songorine, an Agonist of Fibroblast Growth Factor Receptors - G. N. Zyuz’kov; E. A. Losev; N. I. Suslov; L. A. Miroshnichenko; T. Yu. Polyakova; E. V. Simanina; L. A. Stavrova; V. I. Agafonov; M. G. Danilets; V. V. Zhdanov (Bulletin of Experimental Biology and Medicine, 2024)

Kelp breeding in China: Challenges and opportunities for solutions - Zi‐Min Hu; Ti‐Feng Shan; Quan‐Sheng Zhang; Fu‐Li Liu; Alexander Jueterbock; Gaoge Wang; Zhong‐Min Sun; Xiang‐Yu Wang; Wei‐Zhou Chen; Alan T. Critchley; Nai‐Hao Ye (Reviews in Aquaculture, 2024)
Breeding has played an important role in the mariculture and industrialization of kelp in China. However, the current kelp breeding systems in China have encountered some problems relating to germplasm diversity, management, technological innovations, and regional co‐operation. This review summarizes the main challenges, such as top‐down and fragmented management of germplasm libraries, as well as private industry breeding without government regulations, inter‐cultivar accidental admixing and genetic erosion, loss of heterozygosity due to repeated selection and self‐crossing. We outline multiple potential approaches to breed cultivars with improved qualitative/quantitative traits which can be subjected to changing environments, for example: (i) establishing a national germplasm repository to enhance integrative collection and preservation of kelp resources; (ii) planning and implementing kelp breeding programmes according to strategic priorities and goal‐orientations; (iii) optimizing a hybridization‐based breeding pipeline to produce robust cultivars through the introgression of novel alleles and thus the expression of hybrid vigour; (iv) enriching the high‐quality annotated reference genomes and functional analysis of trait‐associated markers/loci to develop DNA‐based breeding technologies; (v) developing new priming‐based (e.g., thermal and disease resistance) bio‐engineering breeding strategies to meet future unpredictable climate change; and (vi) breeding towards an ecological kelp‐microbiome interaction‐based technique to produce cultivars with enhanced performance and adaptability to environmental scenarios. Collectively, the lessons learned from kelp breeding in China and the solutions proposed here may not only potentially improve or re‐invigorate the Chinese kelp industry, but will also assist other developing countries in taking corrective actions to develop a sustainable future kelp farming industry.

Development of a PEI-coated SWNTs Nanocarrier for efficient delivery of CRISPR/Cas9 in early embryos of Litopenaeus vannamei - Jia L. Men; Yu T. Zhang; Yue B. Pei; Na Li; Jian H. Xiang; Hai L. Zhou (Aquaculture, 2024)

Edge computing in wildlife behavior and ecology - Hui Yu; Guillermo J. Amador; Antoine Cribellier; Marcel Klaassen; Henrik J. de Knegt; Marc Naguib; Reindert Nijland; Lukasz Nowak; Herbert H.T. Prins; Lysanne Snijders; Chris Tyson; Florian T. Muijres (Trends in Ecology & Evolution, 2024)

Vegetation−fire feedbacks increase subtropical wildfire risk in scrubland and reduce it in forests - P. Wei; B. Lamont; T. He; W. Xue; P.C. Wang; W. Song; R. Zhang; A.B. Keyhani; S. Zhao; W. Lu; F. Dong; R. Gao; et al. (Journal of Environmental Management, 2024)

Application of image-based diffusion coefficients in multi-scale simulation of coalbed methane reservoirs - Meng Yuan; Yu Jing; Guangyao Si; Ryan T. Armstrong; Peyman Mostaghimi (Fuel, 2024)

Polymorphism in Genes Encoding Adaptor Proteins ST13 and STIP1 and the Risk of Ischemic Stroke: a Pilot Study - T. A. Stetskaya; A. B. Krapiva; K. A. Kobzeva; D. E. Gurtovoy; G. V. Komkova; A. V. Polonikov; O. Yu. Bushueva (Bulletin of Experimental Biology and Medicine, 2024)

Antibiotic Adjuvant 4-Hexylresorcinol Enhances the Efficiency of Antituberculosis Drugs - Yu. A. Nikolaev; T. N. Mukhina; V. D. Potapov; B. B. Kuznetsov; G. I. El’-Registan; V. V. Firstova; I. G. Shemyakin; O. Yu. Manzenyuk (Bulletin of Experimental Biology and Medicine, 2024)

Global Patterns of Metal and Other Element Enrichment in Bog and Fen Peatlands - Chetwynd Osborne; Spencer Gilbert-Parkes; Graeme Spiers; Louis James Lamit; Erik A. Lilleskov; Nathan Basiliko; Shaun Watmough; Roxanne Andersen; Rebekka E. Artz; Brian W. Benscoter; Luca Bragazza; Suzanna L. Bräuer; et al. (Archives of Environmental Contamination and Toxicology, 2024)

Calcium and the ecology of photosynthesis in purple sulfur bacteria - Michael T. Madigan; W. Matthew Sattley; Yukihiro Kimura; Zheng‐Yu Wang‐Otomo (Environmental Microbiology, 2024)
The ecological success of purple sulfur bacteria (PSB) is linked to their ability to collect near‐infrared solar energy by membrane‐integrated, pigment–protein photocomplexes. These include a Core complex containing both light‐harvesting 1 (LH1) and reaction centre (RC) components (called the LH1–RC photocomplex) present in all PSB and a peripheral light‐harvesting complex present in most but not all PSB. In research to explain the unusual absorption properties of the thermophilic purple sulfur bacterium Thermochromatium tepidum , Ca 2+ was discovered bound to LH1 polypeptides in its LH1–RC; further work showed that calcium controls both the thermostability and unusual spectrum of the Core complex. Since then, Ca 2+ has been found in the LH1–RC photocomplexes of several other PSB, including mesophilic species, but not in the LH1–RC of purple non‐sulfur bacteria. Here we focus on four species of PSB—two thermophilic and two mesophilic—and describe how Ca 2+ is integrated into and affects their photosynthetic machinery and why this previously overlooked divalent metal is a key nutrient for their ecological success.

Observations and study of the orbital dynamics of some near-Sun asteroids - T. Yu Galushina; O.N. Letner; A.V. Shein; E.S. Bakanas; P.A. Levkina (Planetary and Space Science, 2024)

Visualisation of [11C]CO2 storage in coal with positron emission tomography imaging - Yu Jing; Aaron Uthaia Kumaran; Damion Stimson; Karine Mardon; Ljubco Najdovski; Christoph Barkhausen; Ryan T. Armstrong; Peyman Mostaghimi (Fuel, 2024)

Long-term ozone exposure and lung function in middle childhood - Marnie F. Hazlehurst; Logan C. Dearborn; Allison R. Sherris; Christine T. Loftus; Margaret A. Adgent; Adam A. Szpiro; Yu Ni; Drew B. Day; Joel D. Kaufman; Neeta Thakur; Rosalind J. Wright; Sheela Sathyanarayana; et al. (Environmental Research, 2024)

Stress-Tolerant Dormant Bacterial Forms: Biological and Ultrastructural Properties of Moraxella catarrhalis and Kocuria rhizophila - O. Yu. Manzenyuk; N. E. Suzina; Yu. A. Nikolaev; T. N. Mukhina; V. V. Firstova; G. I. El’-Registan; I. G. Shemyakin; I. A. Dyatlov (Bulletin of Experimental Biology and Medicine, 2024)

Morphology and ultrastructure of digestive system in pre-zoea and zoea I larvae of red king crab, Paralithodes camtschaticus (Tilesius, 1815) - Nadezhda V. Kalacheva; Talia T. Ginanova; Yaroslav O. Kamenev; Sergey I. Maslennikov; Igor Yu. Dolmatov (Cell and Tissue Research, 2024)

An algorithm for electrocardiosignals processing in a multielectrode electrocardiological screening system for visualization of the electrical potential of the epicardium - M. N. Kramm; T. L. N. Truong; A. Yu. Bodin; O. N. Bodin; G. V. Zhikhareva (Biomedical Engineering, 2024)

Stronger control of surface conductance by soil water content than vapor pressure deficit regulates evapotranspiration in an urban forest in Beijing, 2012–2022 - Xinhao Li; Tianshan Zha; T. Andrew Black; Xin Jia; Rachhpal S. Jassal; Peng Liu; Yun Tian; Chuan Jin; Ruizhi Yang; Feng Zhang; Haiqun Yu; Jing Xie (Agricultural and Forest Meteorology, 2024)

What causes site-specific intra-event variations of stable isotopes in precipitation in Beijing? - Yu Tang; Haoran Li; Anran Liao; Lihu Yang; Katja T. Rinne-Garmston; Dongxu Yao; Wenjia Wang; Xianfang Song (Atmospheric Research, 2023)

Dose-dependent effect of H2O2 on hairy roots of Scutellaria baicalensis: growth, composition of fatty acids, and flavones - A. I. Solov’eva; A. Y. Stepanova; T. V. Ivanova; A. S. Voronkov; Yu. M. Panov (Plant Cell, Tissue and Organ Culture (PCTOC), 2023)

Response of streamflow and nutrient loads in a small temperate catchment subject to land use change - Gebiaw T. Ayele; Bofu Yu; Andy Bruere; David P. Hamilton (Environmental Monitoring and Assessment, 2023)
The aim of this study was to quantify the effect of land use change (LUC) implemented to meet nutrient load targets for a freshwater lake in New Zealand. We used the Soil and Water Assessment Tool (SWAT) model in combination with a non-parametric statistical test to determine whether afforestation of 15% of a subcatchment area was adequate to meet assigned nutrient load targets. A regional management authority set nutrient load targets of reduction in total nitrogen (TN) by 0.9 t yr −1 and reduction in total phosphorus (TP) by 0.05 t yr −1 to avoid eutrophication in the receiving waters of a freshwater lake. The load reduction was designed to be achieved through 200 ha of LUC from pasture to trees. Analysis of nutrient loads before, during, and following LUC shows that a 15% increase in forest cover decreased the annual flow (7.2%), TP load (33.3%), and TN load (13.1%). As flow and water quality observations were discrete and at irregular intervals, we used a parametric test and the SWAT model as different lines of evidence to demonstrate the effect of afforestation on flow and water quality. Policymakers concerned with decisions about LUC to improve the quality of receiving waters can benefit from applying our findings and using a statistical and numerical modelling framework to evaluate the adequacy of land use change to support improvements in water quality.

Zinc isotopes reveal disparate enriched sources of contemporary lamprophyres in Eastern Dharwar Craton - Jian-Qiang Liu; Li-Hui Chen; Xiao-Jun Wang; Lukáš Krmíček; Gang Zeng; Xiao-Yu Zhang; David T. Murphy; Hayden Dalton; Ashutosh Pandey; N. V. Chalapathi Rao (Contributions to Mineralogy and Petrology, 2023)

Age-Related Features of the Early Period of Liver Regeneration after Partial Hepatectomy in Rats - E. S. Pan; N. N. Ermakova; O. V. Pershina; A. V. Pakhomova; M. A. Zhukova; L. A. Sandrikina; L. V. Kogai; S. A. Afanas’ev; T. Yu. Rebrova; V. A. Korepanov; S. G. Morozov; A. A. Kubitaev; et al. (Bulletin of Experimental Biology and Medicine, 2023)

Selective Accumulation of Poly(Lactic-Co-Glycolic Acid) Nanoparticles in Endotheliocytes and Mesenchymal Stromal Cells Cultured as Mixed-Cell Spheroids - G. E. Leonov; I. V. Vakhrushev; V. D. Novikova; V. V. Burunova; T. S. Kovshova; Yu. A. Malinovskaya; K. N. Yarygin (Bulletin of Experimental Biology and Medicine, 2023)

The Effect of Vitamin D3 on Neutrophil Extracellular Trap Formation in High-Glucose Conditions - L. Yu. Basyreva; E. V. Shmeleva; V. A. Ivanov; T. V. Vakhrusheva; O. M. Panasenko; E. M. Ostrovsky; S. A. Gusev; V. I. Sergienko (Bulletin of Experimental Biology and Medicine, 2023)

Establishment of a developmental atlas and transgenetic tools in the ascidian Styela clava - Boyan Lin; Wenjie Shi; Qiongxuan Lu; Takumi T. Shito; Haiyan Yu; Bo Dong (Marine Life Science & Technology, 2023)

Experimental measurements and numerical simulations of the transport and retention of nanocrystal CdSe/ZnS quantum dots in saturated porous media: Effects of electrolytes, organic ligand, and natural organic matter - Chunyan Li; Asra Hassan; Marcell Palmai; Yu Xie; Preston T. Snee; Brian A. Powell; Lawrence C. Murdoch; Christophe J.G. Darnault (Science of The Total Environment, 2023)

Shift in symbiotic lifestyle as the major process shaping the evolution of pea crabs (Decapoda: Brachyura: Pinnotheroidea) - Lai Him Chow; Shane T. Ahyong; Chandler T.T. Tsang; Yu Fung Lam; Tohru Naruse; Peter K.L. Ng; Ling Ming Tsang (Molecular Phylogenetics and Evolution, 2023)

Cognitive Impairments in Emotional Burnout Syndrome - L. S. Chutko; E. A. Yakovenko; S. Yu. Surushkina; A. V. Rem; T. I. Anisimova; V. A. Ponomarev; Yu.D. Kropotov; A. V. Sergeev; D. V. Cherednichenko; M. D. Didur (Neuroscience and Behavioral Physiology, 2023)

Functional Activity of Blood Neutrophils in Patients with Stable Course and Exacerbation of Chronic Obstructive Pulmonary Disease - N. I. Kubysheva; L. B. Postnikova; V. V. Novikov; S. K. Soodaeva; T. I. Eliseeva; E. I. Khrapunova; A. B. Stroganov; D. Yu. Ovsyannikov; A. V. Karaulov (Bulletin of Experimental Biology and Medicine, 2023)

Characteristics of the use of scanning capillary microscopy in biomedical research - T. O. Sovetnikov; A. I. Akhmetova; N. E. Maksimova; A. D. Terent’ev; G. S. Evtushenko; Yu. L. Rybakov; V. M. Gukasov; I. V. Yaminskii (Biomedical Engineering, 2023)

Development and application of influenza virus wastewater surveillance in Hong Kong - Xiawan Zheng; Keyue Zhao; Xiaoqing Xu; Yu Deng; Kathy Leung; Joseph T. Wu; Gabriel M. Leung; Malik Peiris; Leo L.M. Poon; Tong Zhang (Water Research, 2023)

Biohydrogen production through dark fermentation from waste biomass: Current status and future perspectives on biorefinery development - Tinku Casper D' Silva; Sameer Ahmad Khan; Subodh Kumar; Dushyant Kumar; Adya Isha; Saptashish Deb; Saurabh Yadav; Biju Illathukandy; Ram Chandra; Virendra Kumar Vijay; Paruchuri M.V. Subbarao; Zoltán Bagi; et al. (Fuel, 2023)

Model uncertainties and partial safety factors of strain-based approaches for structural concrete: Example of punching shear - Qianhui Yu; João T. Simões; Aurelio Muttoni (Engineering Structures, 2023)

The Role of Inflammation in the Development of Diabetic Polyneuropathy and the Potential for Its Correction - L. A. Shchepankevich; M. A. Pervuninskaya; I. A. Gribacheva; T. F. Popova; Yu. A. Nicolaev; E. V. Taneeva; E. V. Petrova; M. S. Shchepankevich (Neuroscience and Behavioral Physiology, 2023)

Role of hydrogen-bond networks on the donor side of photosynthetic reaction centers from purple bacteria - T. Yu. Fufina; L. G. Vasilieva (Biophysical Reviews, 2023)

Prospects for meteotsunami detection in earth’s atmosphere using GNSS observations - Panagiotis Vergados; Siddharth Krishnamoorthy; Léo Martire; Sebastijan Mrak; Attila Komjáthy; Yu T. Jade Morton; Ivica Vilibić (GPS Solutions, 2023)
We study, for the first time, the physical coupling and detectability of meteotsunamis in the earth’s atmosphere. We study the June 13, 2013 event off the US East Coast using Global Navigation Satellite System (GNSS) radio occultation (RO) measurements, Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) temperatures, and ground-based GNSS ionospheric total electron content (TEC) observations. Hypothesizing that meteotsunamis also generate gravity waves (GWs), similar to tsunamigenic earthquakes, we use linear GW theory to trace their dynamic coupling in the atmosphere by comparing theory with observations. We find that RO data exhibit distinct stratospheric GW activity at near-field that is captured by SABER data in the mesosphere with increased vertical wavelength. Ground-based GNSS-TEC data also detect a far-field ionospheric response 9 h later, as expected by GW theory. We conclude that RO measurements could increase understanding of meteotsunamis and how they couple with the earth’s atmosphere, augmenting ground-based GNSS TEC observations.

Effects of source materials on desorption kinetics of carcinogenic PAHs from contaminated soils - Linbo Yu; Luchun Duan; Ravi Naidu; Fanbo Meng; Kirk T. Semple (Chemosphere, 2023)

Microplastics removal in the aquatic environment via fungal pelletization - Huaimin Wang; Brian Neal; Bert White; Bill Nelson; Jingru Lai; Bin Long; Jorge Arreola-Vargas; Jiali Yu; Mark T. Banik; Susie Y. Dai (Bioresource Technology Reports, 2023)

Changes in mean and extreme homogeneous precipitation in China during 1960–2020 - Yanjuan Wu; Hongli Mu; Shuang-ye Wu; Yu Xu; Ming Xu; Huawu Wu; Robin T. Clark; Chao Gao (Atmospheric Research, 2023)

Formation of the mesodermal organs during the metamorphosis and definitive organogenesis in the holothurian Apostichopus japonicus - Igor Yu. Dolmatov; Talia T. Ginanova; Marina G. Eliseikina; Lidia T. Frolova (Zoomorphology, 2023)

Correction: Preventive Pharmacovigilance: timely and precise prevention of adverse events through person-level patient screening and dose-level product surveillance - Yihua Bruce Yu; Katharine T. Briggs; Marc B. Taraban (Pharmaceutical Research, 2023)

Preventive Pharmacovigilance: timely and precise prevention of adverse events through person-level patient screening and dose-level product surveillance - Yihua Bruce Yu; Katharine T. Briggs; Marc B. Taraban (Pharmaceutical Research, 2023)
The goal of pharmacovigilance (PV) is to prevent adverse events (AEs) associated with drugs and vaccines. Current PV programs are of a reactive nature and rest entirely on data science, i.e., detecting and analyzing AE data from provider/patient reports, health records and even social media. The ensuing preventive actions are too late for people who have experienced AEs and often overly broad, as responses include entire product withdrawals, batch recalls, or contraindications of subpopulations. To prevent AEs in a timely and precise manner, it is necessary to go beyond data science and incorporate measurement science into PV efforts through person-level patient screening and dose-level product surveillance. Measurement-based PV may be called ‘preventive pharmacovigilance’, the goal of which is to identify susceptible individuals and defective doses to prevent AEs. A comprehensive PV program should contain both reactive and preventive components by integrating data science and measurement science.

Ultrastructural Reorganization of Endotheliocytes of Pulmonary Blood Capillaries in COVID-19 - N. P. Bgatova; S. V. Savchenko; A. N. Lamanov; M. Zh. Ergazina; M. T. Adilova; A. Yu. Letyagin (Bulletin of Experimental Biology and Medicine, 2023)

Evaluating the factors influencing the location strategies of specialty grocers versus traditional supermarkets in the United States - Connor Reed; T. Edward Yu; David Hughes (Applied Geography, 2023)

Snow-corrected vegetation indices for improved gross primary productivity assessment in North American evergreen forests - Ran Wang; David R. Bowling; John A. Gamon; Kenneth R. Smith; Rong Yu; Gabriel Hmimina; Masahito Ueyama; Asko Noormets; Thomas E. Kolb; Andrew D. Richardson; Charles P.A. Bourque; Rosvel Bracho; et al. (Agricultural and Forest Meteorology, 2023)

Perturbations in the characteristics of ionospheric HF radio waves during the April 11, 2019, earthquake in Japan: Results from oblique sounding - Leonid F. Chernogor; Kostyantyn P. Garmash; Qiang Guo; Victor T. Rozumenko; Yu Zheng (Advances in Space Research, 2023)

Sex-dependent associations of plasma high-density lipoprotein cholesterol and mortality risk in healthy older men and women: two prospective cohort studies - Sultana Monira Hussain; Andrew M Tonkin; Gerald F Watts; Paul Lacaze; Chenglong Yu; Lawrence J Beilin; Zhen Zhou; Anne B Newman; Johannes T Neumann; Cammie Tran; John J McNeil (GeroScience, 2023)
The relationship between high plasma high-density lipoprotein cholesterol (HDL-C) and cause and mortality are not well established in healthy older people. This study examined the associations between HDL-C levels and mortality in initially healthy older men and women. This analysis included participants from the Aspirin in Reducing Events in the Elderly (ASPREE; n =18,668) trial and a matched cohort from the UK Biobank (UKB; n =62,849 ≥65 years). Cox regression was used to examine hazard ratios between HDL-C categories <1.03 mmol/L, 1.03–1.55 mmol/L (referent category), 1.55–2.07 mmol/L, and >2.07 mmol/L and all-cause, cancer, cardiovascular disease (CVD), and “non-cancer non-CVD” mortality. Genetic contributions were assessed using a polygenic score for HDL-C. Among ASPREE participants (aged 75±5 years), 1836 deaths occurred over a mean follow-up of 6.3±1.8 years. In men, the highest category of HDL-C levels was associated with increased risk of all-cause (HR 1.60, 95% CI 1.26–2.03), cancer (HR 1.37, 95% CI 0.96–2.00), and “non-cancer non-CVD” mortality (HR 2.35, 95% CI 1.41–3.42) but not CVD mortality (HR 1.08, 95% CI 0.60–1.94). The associations were replicated among UKB participants (aged 66.9±1.5 years), including 8739 deaths over a mean follow-up of 12.7±0.8 years. There was a non-linear association between HDL-C levels and all-cause and cause-specific mortality. The association between HDL-C levels and mortality was unrelated to variations in the HDL-C polygenic score. No significant association was found between HDL-C levels and mortality in women. Higher HDL-C levels are associated with increased risk from cancer and “non-cancer non-CVD” mortality in healthy older men but no such relationship was observed in women.

Genomic basis for the unique phenotype of the alkaliphilic purple nonsulfur bacterium Rhodobaca bogoriensis - Michael T. Madigan; Kelly S. Bender; Sophia A. Sanguedolce; Mary N. Parenteau; Marisa H. Mayer; Yukihiro Kimura; Zheng-Yu Wang-Otomo; W. Matthew Sattley (Extremophiles, 2023)

Preparation of a Single-Cell Suspension from Tumor Biopsy Samples for Single-Cell RNA Sequencing - A. A. Frolova; T. S. Gerashchenko; M. R. Patysheva; A. A. Fedorov; M. M. Tsyganov; U. A. Bokova; O. D. Bragina; M. A. Vostrikova; E. Yu. Garbukov; N. V. Cherdyntseva (Bulletin of Experimental Biology and Medicine, 2023)

Endogenous Regeneration of Alveolar Bone by Decellularized Tooth Matrix - A. V. Latyshev; T. I. Danilova; A. V. Kuznetsova; O. P. Popova; N. N. Butorina; A. Yu. Drobyshev; A. A. Ivanov (Bulletin of Experimental Biology and Medicine, 2023)

Geological controls on the distribution of gas hydrates in the shallow parts of the gas hydrate stability zone – constraints from seafloor drilling off Taiwan - G. Bohrmann; C. Berndt; S. Lin; T.-H. Tu; A.T. Lin; H.-H. Hsu; M.-C. Lai; W.-C. Chi; C. Deusner; J. Elger; K. Wallmann; T. Freudenthal; et al. (Marine and Petroleum Geology, 2023)

Multigenerational impacts of EE2 on reproductive fitness and immune competence of marine medaka - Drew R. Peterson; Frauke Seemann; Miles T. Wan; Roy R. Ye; Lianguo Chen; Keng P. Lai; Peter Yu; Richard Y.C. Kong; Doris W.T. Au (Aquatic Toxicology, 2023)

The Neurobiological Role of Lithium Salts - I. V. Gogoleva; O. A. Gromova; I. Yu. Torshin; T. R. Grishina; A. V. Pronin (Neuroscience and Behavioral Physiology, 2023)

CLDN6 Suppresses Migration and Invasion of MCF-7 and SKBR-3 Breast Cancer Cells by Blocking the SMAD/Snail/MMP-2/9 Axis - T. Liu; L. Jiang; Q. Bai; S. Wu; X. Yu; T. Wu; J. Wang; X. Zhang; H. Li; K. Zhao; L. Wang (Bulletin of Experimental Biology and Medicine, 2023)

Mapping cellular senescence networks in human diabetic foot ulcers - Grace T. Yu; Dileep D. Monie; Sundeep Khosla; Tamar Tchkonia; James L. Kirkland; Saranya P. Wyles (GeroScience, 2023)

Marine fishes of Palawan, Philippines: Species diversity, new records, and conservation status - Rodulf Anthony T. Balisco; Victor S. Ticzon; Badi R. Samaniego; Wen-Chien Huang; Benjamin J. Gonzales; Te-Yu Liao (Regional Studies in Marine Science, 2023)

Advanced destruction technologies for PFAS in soils: Progress and challenges - Yu-Gyeong Kang; Quinn T. Birch; Mallikarjuna N. Nadagouda; Dionysios D. Dionysiou (Current Opinion in Environmental Science & Health, 2023)

Assessing Antigen-Adjuvant Complex Stability Against Physical Stresses By wNMR - Marc B. Taraban; Katharine T. Briggs; Yihua Bruce Yu; Michael T. Jones; Lindsey Rosner; Akhilesh Bhambhani; Donna M. Williams; Christopher Farrell; Mikhail Reibarkh; Yongchao Su (Pharmaceutical Research, 2023)

Association of the rs1344706 Polymorphism of the ZNF804A Gene with Induced EEG Rhythm Changes during Visual Perception of Verbal Stimuli in Healthy and Schizophrenic Subjects - Zh. V. Garakh; V. E. Golimbet; E. V. Larionova; T. V. Lezheiko; V. B. Strelets; Yu. S. Zaytseva (Neuroscience and Behavioral Physiology, 2023)

Immunopatological and Genetic Aspects of the Pathogenesisof CNS Lesions in VZV Infection - E. Yu. Skripchenko; G. F. Zheleznikova; N. V. Skripchenko; L. A. Alekseeva; O. V. Goleva; T. V. Bessonova; A. A. Zhirkov (Neuroscience and Behavioral Physiology, 2023)

Spatial and temporal scaling of sub-daily extreme rainfall for data sparse places - R. L. Wilby; C. W. Dawson; D. Yu; Z. Herring; A. Baruch; M. J. Ascott; D. L. Finney; D. M. J. Macdonald; J. H. Marsham; T. Matthews; C. Murphy (Climate Dynamics, 2023)
Global efforts to upgrade water, drainage, and sanitation services are hampered by hydrometeorological data-scarcity plus uncertainty about climate change. Intensity–duration–frequency (IDF) tables are used routinely to design water infrastructure so offer an entry point for adapting engineering standards. This paper begins with a novel procedure for guiding downscaling predictor variable selection for heavy rainfall simulation using media reports of pluvial flooding. We then present a three-step workflow to: (1) spatially downscale daily rainfall from grid-to-point resolutions; (2) temporally scale from daily series to sub-daily extreme rainfalls and; (3) test methods of temporal scaling of extreme rainfalls within Regional Climate Model (RCM) simulations under changed climate conditions. Critically, we compare the methods of moments and of parameters for temporal scaling annual maximum series of daily rainfall into sub-daily extreme rainfalls, whilst accounting for rainfall intermittency. The methods are applied to Kampala, Uganda and Kisumu, Kenya using the Statistical Downscaling Model (SDSM), two RCM simulations covering East Africa (CP4 and P25), and in hybrid form (RCM-SDSM). We demonstrate that Gumbel parameters (and IDF tables) can be reliably scaled to durations of 3 h within observations and RCMs. Our hybrid RCM-SDSM scaling reduces errors in IDF estimates for the present climate when compared with direct RCM output. Credible parameter scaling relationships are also found within RCM simulations under changed climate conditions. We then discuss the practical aspects of applying such workflows to other city-regions.

Candida species causing fungal keratitis: molecular identification, antifungal susceptibility, biofilm formation, and clinical aspects - Fernanda M. Bezerra; Talita T. Rocchetti; Soraia L. Lima; Maria Cecília Z. Yu; Daniel A. da Matta; Ana Luisa Höfling-Lima; Analy S. A. Melo; Lauro A. de Oliveira (Brazilian Journal of Microbiology, 2023)

Redox homeostasis of cereals during acclimation to drought - Yu. E. Kolupaev; T. O. Yastreb; N. I. Ryabchun; A. I. Kokorev; V. P. Kolomatska; A. P. Dmitriev (Theoretical and Experimental Plant Physiology, 2023)

Modelling multicomponent gas diffusion and predicting the concentration-dependent effective diffusion coefficient of coal with application to carbon geo-sequestration - Meng Yuan; Yu Jing; Zakhar Lanetc; Aleksandr Zhuravljov; Fatemeh Soleimani; Guangyao Si; Ryan T. Armstrong; Peyman Mostaghimi (Fuel, 2023)

Prevention of the Genotoxic Effects of Doxorubicin with Anthocyanin-Containing Complex from Sorbus aucuparia L. Fruit - O. Yu. Rybalkina; O. V. Neupokoeva; O. L. Voronova; T. G. Razina; G. I. Kalinkina; N. V. Isaikina; E. A. Kiseleva; A. A. Churin; E. P. Zueva; V. V. Zhdanov (Bulletin of Experimental Biology and Medicine, 2023)

Participation of cAMP-Mediated Signaling Transduction in the Regulation of the Secretory Function of Neuroglia during Ethanol-Induced Neurodegeneration - G. N. Zyuz’kov; V. V. Zhdanov; L. A. Miroshnichenko; T. Yu. Polyakova; E. V. Simanina; M. G. Danilets; V. I. Agafonov; L. A. Stavrova (Bulletin of Experimental Biology and Medicine, 2023)

A Fiber-Optic Scanner for Determining the Morphometric Parameters of the Palate in Patients - T. I. Murashkina; E. A. Badeeva; T. V. Istomina; T. V. Gaivoronskaya; E. Yu. Plotnikova; T. V. Parshikova (Biomedical Engineering, 2023)

The contrast in suspended particle dynamics at surface and near bottom on the river-dominated northern South China Sea shelf in summer: implication on physics and biogeochemistry coupling - Jay Lee; James T. Liu; Yu-Shih Lin; Chen-Tung Arthur Chen; Bo-Shian Wang (Frontiers in Marine Science, 2023)
To understand the process-response relations among physical forcing and biogeochemical properties of suspended particles (SPs) in the river-dominated northern South China Sea shelf, a 5-day shipboard observation was conducted at a fixed location on the dispersal pathway of the Zhujiang (Pearl) River plume (ZRP) in the summer of 2016. Instrumented moorings were deployed near the sampling site to record the flow and wave fields every 10 minutes. Hydrographic properties were measured hourly to identify different water masses. Water and SPs samples at the surface (3 m) and near the bottom (3 m above the bed) were taken every 3 h for the analyses of nutrients, chlorophyll-a (Chl-a), and particulate organic matter (POM including POC, PN, and δ 13 C POC ). Meanwhile, the grain-size composition of SPs and seafloor sediment were also analyzed. Results showed that monsoon winds drove cold upwelling and ZRP waters at the surface. Both the upwelling and ZRP regimes contained newly produced marine phytoplankton based on low POC/Chl-a ratio (PC ratio) and enriched δ 13 C POC. However, SPs in the ZRP regime were smaller (<153 µm), having denser particle bulk density, and less enriched δ 13 C POC , indicating different bio-communities from the upwelling regime. EOF analysis of the surface data suggested that mixing processes and the dispersal of the ZRP regime were mainly controlled by far-field storm winds, tidal modulation, and strength of mixing. On the other hand, a bottom nepheloid layer (BNL) was observed, mainly consisting of SPs<63 μm with higher bulk density than SPs at the surface. POM in the BNL was degraded and δ 13 C POC -depleted according to the PC ratio and δ 13 C POC . EOF analysis of the near-bottom data indicated that the dominant physical processes influencing the biogeochemical properties of SPs in the BNL were jointly the upwelling-associated lateral transport (first order) and tide-related resuspension (second order). Our study identified the contrast between the surface and near-bottom regimes with the coupling patterns among physical forcing and physiochemical properties of SPs using good constraints on particle dynamics and particle sources.

Punctiform Breakup and Initial Oceanization in the Central Red Sea Rift - Ya-Di Sang; Bakhit M. T. Adam; Chun-Feng Li; Liang Huang; Yong-Lin Wen; Jia-Ling Zhang; Yu-Tao Liu (Journal of Marine Science and Engineering, 2023)
The Central Red Sea Rift is a natural laboratory to study the transition from rifting to spreading. Based on new reflection seismic profiles and gravity modeling, we examined the crustal structure, tectonic evolution, breakup mechanism, and future evolution of the Central Red Sea Rift. Along this rift axis, the breakup of continental lithosphere is discontinuous and the oceanic crust is limited to the axial deeps. The punctiform breakup and formation of deeps is assisted by mantle upwelling and topographic uplift, but the nucleation is directly controlled by the normal-fault system. The discontinuities spaced between axial deeps within the relatively continuous central troughs are presently axial domes or highs and will evolve into new deeps with tectonic subsidence. Isolated deeps will grow and connect with each other to become a continuous central trough, before transitioning into a unified spreading center.

Regional variability in peatland burning at mid-to high-latitudes during the Holocene - Thomas G. Sim; Graeme T. Swindles; Paul J. Morris; Andy J. Baird; Angela V. Gallego-Sala; Yuwan Wang; Maarten Blaauw; Philip Camill; Michelle Garneau; Mark Hardiman; Julie Loisel; Minna Vӓliranta; et al. (Quaternary Science Reviews, 2023)

The construction of synthetic communities improved the yield and quality of Salvia miltiorrhiza Bge. - Hong-M. Jia; Bo Li; Yu-R. Wu; Yun-T. Ma; Zhu-Y. Yan (Journal of Applied Research on Medicinal and Aromatic Plants, 2023)

Modeling and model updating of a full-scale experimental base-isolated building - Tianhao Yu; Erik A. Johnson; Patrick T. Brewick; Richard E. Christenson; Eiji Sato; Tomohiro Sasaki (Engineering Structures, 2023)

Status and prospects of tree-ring research in Central Asia - Tongwen Zhang; Kexiang Liu; Yuting Fan; Shulong Yu; Ruibo Zhang; Huaming Shang; Yujiang Yuan; Wenshou Wei; Qing He; Heli Zhang; Bakytbek Ermenbaev; Rysbek Satylkanov; et al. (Dendrochronologia, 2023)

Assessment of Cognitive Functions in Patients Accidentally Exposed to Radiation - E. A. Litvinchuk; T. E. Kantina; E. Yu. Burtovaia (Neuroscience and Behavioral Physiology, 2023)

Effect of Sodium Lauryl Sulfate on Sorption of Cells of the Electrogenic Bacterium Strain Micrococcus luteus on Carbon Cloth - D. I. Stom; M. N. Saksonov; E. I. Gavlik; G. O. Zhdanova; S. A. Sasim; T. Ph. Kazarinova; M. Yu. Tolstoy; J. Gescher (Indian Journal of Microbiology, 2023)

The Dependence of the Electrophysiological Effects of Class III Antiarrhythmic Drug Refralon on the Frequency of Myocardium Activation - D. V. Abramochkin; O. B. Pustovit; N. Yu. Mironov; T. S. Filatova; V. S. Kuzmin (Bulletin of Experimental Biology and Medicine, 2023)

Effects of the Maternal Environment on Early Postnatal Development in OXYS Rats - T. N. Igonina; O. M. Voronkova; D. S. Ragaeva; E. Yu. Brusentsev; I. N. Rozhkova; N. G. Kolosova; S. Ya. Amstislavsky (Neuroscience and Behavioral Physiology, 2023)

On the occurrence of low concentration hyperpycnal river plumes in a small mountainous river-canyon system - Sheng-De Tsai; Yu-Chi Lin; Andhy Romdani; Jia-Lin Chen; Ray T. Hsu; James T. Liu (Continental Shelf Research, 2023)

Effect of Changes in the Redox Status on Biofilm Formation in Escherichia coli - T. V. Kalashnikova; L. V. Sutormina; Z. Yu. Samoilova; O. N. Oktyabrsky; G. V. Smirnova (Bulletin of Experimental Biology and Medicine, 2023)

MTNR1A and MTNR1B Gene Variants of the Melatonin Receptor and Arterial Stiffness in Persons without Arterial Hypertension - S. N. Kolomeichuk; V. A. Korneva; T. Yu. Kuznetsova; L. S. Korostovtseva; M. V. Bochkarev; Yu.V. Sviryaev; M. L. Blagonravov (Bulletin of Experimental Biology and Medicine, 2023)

Comparative analysis of four types of mesoscale eddies in the North Pacific Subtropical Countercurrent region - part II seasonal variation - Wenjin Sun; Mengxuan An; Jishan Liu; Jie Liu; Jingsong Yang; Wei Tan; Kenny T. C. Lim Kam Sian; Jinlin Ji; Yu Liu; Changming Dong (Frontiers in Marine Science, 2023)
The North Pacific Subtropical Countercurrent area (STCC) is high in mesoscale eddy activities. According to the rotation direction of the eddy flow field and the sign of temperature anomaly within the eddy, they can be divided into four categories: cyclonic cold-core eddy (CCE), anticyclonic warm-core eddy (AWE), cyclonic warm-core eddy (CWE) and anticyclonic cold-core eddy (ACE). CCE and AWE are called normal eddies, and CWE and ACE are named abnormal eddies. Based on the OFES data and vector geometry automatic detection method, we find that at the sea surface, the maximum monthly number of the CCE, AWE, CWE, and ACE occurs in December (765.70 ± 52.05), January (688.20 ± 82.53), August (373.40 ± 43.09) and August (533.00 ± 56.92), respectively. The number of normal eddies is more in winter and spring, and less in summer and autumn, while abnormal eddies have the opposite distribution. The maximum rotation velocity of the four types of eddies appears in June (11.71 ± 0.75 cm/s), June (12.24 ± 0.86 cm/s), May (10.63 ± 0.99 cm/s) and June (9.97 ± 0.91 cm/s), which is fast in winter and spring. The moving speed of the four types of eddies is almost similar (about 10 ~ 11 cm/s). The amplitude of normal and abnormal eddies is both high in summer and autumn, and low in winter and spring, with larger amplitudes in normal than abnormal eddies. The eccentricity (defined as the eccentricity of the ellipse obtained by fitting the eddy boundary) of the four types of eddies is also close to each other, and their variation ranges from 0.7 to 0.8, with no apparent seasonal variation. The vertical penetration depth, which has no significant seasonal difference, is 675.13 ± 67.50 m in cyclonic eddies (CCE and CWE), which is deeper than that 622.32 ± 81.85 m in anticyclonic eddies (ACE and AWE). In addition, increasing the defined temperature threshold for abnormal eddies can significantly reduce their numbers but does not change their seasonal variation trend.

Origins of clay-rich strata in Cenozoic paleochannel deposits: an example from Suttor Formation, Queensland - T. Yu; J. Cooling; J. Esterle; T. Chadwick; A. Babaahmadi (Australian Journal of Earth Sciences, 2023)

Nature and evolution of diagenetic fluids in the deeply buried Cambrian Xiaoerbulake Formation, Tarim Basin, China - T. Y. Wei; C. F. Cai; Y. J. Hu; H. Y. Yu; D. W. Liu; Z. W. Jiang; D. W. Wang (Australian Journal of Earth Sciences, 2023)

Multiscale measurements of gas diffusion coefficient of coal using counter-diffusion and image-based methods - Lkhamsuren Baatar; Peyman Mostaghimi; Meng Yuan; Ryan T. Armstrong; Lewis Adler; Ismet Canbulat; Guangyao Si; Batyrkhan Gaidarov; Yu Jing (International Journal of Coal Geology, 2023)

Provenance changes for mineral matter in the latest Permian coals from western Guizhou, southwestern China, relative to tectonic and volcanic activity in the Emeishan Large Igneous Province and Paleo-Tethys region - Minglian Shen; Shifeng Dai; Victor P. Nechaev; David French; Ian T. Graham; Shande Liu; Igor Yu. Chekryzhov; Irina A. Tarasenko; Shaowei Zhang (Gondwana Research, 2023)

Prenatal exposure to polycyclic aromatic hydrocarbons is not associated with behavior problems in preschool and early school-aged children: A prospective multi-cohort study - Erin R. Wallace; Erin Buth; Adam A. Szpiro; Yu Ni; Christine T. Loftus; Erin Masterson; Drew B. Day; Bob Z. Sun; Alexis Sullivan; Emily Barrett; Ruby HN. Nguyen; Morgan Robinson; et al. (Environmental Research, 2023)

Effects of the Spectral Components of Everyday Illumination on the Formation of Eye Structures in the Japanese Quail Coturnix Japonica - N. N. Trofimova; Yu. S. Petronyuk; T. S. Guryeva; E. I. Mednikova; P. P. Zak (Neuroscience and Behavioral Physiology, 2023)

Impairments to Emotional and Behavioral Regulation in Children with Attention Deficit Hyperactivity Disorder - L. S. Chutko; E. A. Yakovenko; S. Yu. Surushkina; T. I. Anisimova; A. V. Sergeev; M. D. Didur; D. V. Cherednichenko (Neuroscience and Behavioral Physiology, 2023)

Constructional Features of a Multielectrode Electrocardiology Screening System - M. N. Kramm; O. N. Bodin; A. Yu. Bodin; T. L. N. Truong; G. V. Zhikhareva (Biomedical Engineering, 2023)

Cooperative feeding and foraging lateralization by Eden's whales off southern China - Bingyao Chen; Caiwen Wu; Lisa T Ballance; Dagmar Fertl; Huiping Jiang; Ying Qiao; Zhuoxuan Du; Yu Zhang; Feng Yang; Guang Yang; Robert L. Pitman (Marine Mammal Science, 2023)
We investigated surface feeding behaviors of Eden's whales ( Balaenoptera edeni edeni ) in northern Beibu Gulf, southern China, between April 3, 2018, and April 26, 2021. During 122 days at sea, 1,065 individual feeding events were recorded, and eight feeding behaviors were identified: two nonlunging (tread‐water and/or trap‐feeding, 7.7%, and a novel behavior we call “pirouette feeding,” 15.3%) and six lunging (right lateral lunging, RLL, 10.9%; left lateral lunging, 0.2%; upright lunging, 6.3%, vertical lunging, 18.5%; inverted lunging, 0.3%; cooperative lateral lunging, COL, 40.9%). During COL, 2–8 whales swam clockwise around a fish school and simultaneously performed RLL on surfacing—the first cooperative feeding behavior recorded for a Balaenoptera whale. Five lateralized feeding behaviors (entailing either a left or right rotation on the long‐body axis) accounted for 65.8% of individual feeding events, with a strong right‐side bias (99.7%). Lateralized behavior is prevalent in many vertebrates, including several species of rorquals, and we suggest that the right‐biased foraging lateralization among rorquals specifically allows them to keep their right eye on their prey (i.e., a sensory versus motor lateralization), and that this shared asymmetry among conspecifics may have preadapted Eden's whale for cooperative foraging.

Endovascular Thrombectomy for Acute Basilar Artery Occlusion: Latest Findings and Critical Thinking on Future Study Design - Wengui Yu; Randall T. Higashida (Translational Stroke Research, 2022)
Randomized controlled trials (RCTs) have demonstrated powerful efficacy of endovascular thrombectomy (EVT) for large vessel occlusion in the anterior circulation. The effect of EVT for acute basilar artery occlusion (BAO) in the posterior circulation remains unproven. Here, we highlight the latest findings of observational studies and RCTs of EVT for BAO, with a focus on the predictors of functional outcomes, the limitations of recent RCTs, and critical thinking on future study design. Pooled data from large retrospective studies showed 36.4% favorable outcome at 3 months and 4.6% symptomatic intracranial hemorrhage (sICH). Multivariate logistic regression analysis revealed that higher baseline NIHSS score, pc-ASPECTS < 8, extensive baseline infarction, large pontine infarct, and sICH were independent predictors of poor outcome. Two recent randomized trial BEST (Endovascular treatment vs. standard medical treatment for vertebrobasilar artery occlusion) and BASICS (Basilar Artery International Cooperation Study) failed to demonstrate significant benefit of EVT within 6 or 8 h after stroke symptom onset. The limitations of these studies include slow enrollment, selection bias, high crossover rate, and inclusion of patients with mild deficit. To improve enrollment and minimize risk of diluting the overall treatment effect, futile recanalization and re-occlusion, optimal inclusion/exclusion criteria, including enrollment within 24 h of last known well, NIHSS score ≥ 10, pc-ASPECTS ≥ 8, no large pontine infarct, and the use of rescue therapy for underlying atherosclerotic stenosis, should be considered for future clinical trials.

Methamphetamine-induced lethal toxicity in zebrafish larvae - Yu Chen; Alexander S. Wisner; Isaac T. Schiefer; Frederick E. Williams; F. Scott Hall (Psychopharmacology, 2022)

Analysis of landslide occurrence time via rainfall intensity and soil water index ternary diagram - Yi-Jun Liu; Yen-Yu Chiu; Frank T.-C. Tsai; Su-Chin Chen (Landslides, 2022)

DNA Damage in Splenocytes of Mice Exposed to Secondary Radiation Created by 650 MeV Protons Bombarding a Concrete Shielding Barrier - T. M. Blokhina; A. A. Ivanov; N. Yu. Vorobyeva; E. I. Yashkina; O. V. Nikitenko; T. M. Bychkova; A. G. Molokanov; G. N. Timoshenko; A. Yu. Bushmanov; A. S. Samoilov; A. N. Osipov (Bulletin of Experimental Biology and Medicine, 2022)

Antinociceptive Effect of Ethowurtzine, a New Compound from the Class of Hexaazaizowurzitane - S. G. Krylova; E. A. Kiseleva; T. N. Povet’eva; Yu. V. Nesterova; O. Yu. Rybalkina; P. V. Kul’pin; O. G. Afanas’eva; D. A. Kulagina; V. V. Eremina; O. V. Baibakova; E. P. Zueva; N. I. Suslov; et al. (Bulletin of Experimental Biology and Medicine, 2022)

Further refinements of a continuous radon monitor for surface ocean water measurements - Chunqian Li; Shibin Zhao; Chenglun Zhang; Meng Li; Jinjia Guo; Natasha T. Dimova; Tong Yang; Wen Liu; Guangquan Chen; Huaming Yu; Bochao Xu (Frontiers in Marine Science, 2022)
Radon is an excellent natural tracer for studying various geophysical processes. In the past centuries, radon isotopes measurement approaches for marine research have been fully developed but still suffer limitations. Here we present the setup and validation of an improved continuous online measurement system (PIC-ORn) to measure dissolved radon in the surface ocean and other water bodies. We demonstrated that the PIC measurement efficiency is ~2 times higher than a RAD7 and is less affected by relative humidity and produces reliable results. Laboratorial measurements indicated that the new PIC-ORn system responded timely to the change of radon activities in water. The new system was successfully deployed during a cruise to the northwest Pacific Ocean in June 2021. Despite low radon-in-water activities, the results obtained by the new PIC-ORn system matched the traditional measurement systems within the estimated uncertainties. The PIC-ORn detector takes advantage of higher efficiency, lower cost, and power consumption, and is less affected by air moisture. The new system does not rely on drying units, further reducing on-site supervision, which would benefit the researches in submarine groundwater advection and diffusion and ocean-atmosphere gas exchange.

Regulation of the Placental Growth Factor Mediated by Sumoylation and Expression of miR-652-3p in Pregnant Women with Early-Onset Preeclampsia - V. A. Gusar; A. V. Timofeeva; V. V. Chagovets; N. E. Kan; T. Yu. Ivanets; G. T. Sukhikh (Bulletin of Experimental Biology and Medicine, 2022)

The Experience of Using Multipotent Mesenchymal Stromal Cells in the Treatment of Severe Recurrent Cholangitis in Children with Biliary Atresia after Kasai Surgery - A. V. Degtyareva; М. H. Isaeva; D. N. Silachev; K. V. Goryunov; Yu. А. Shevtsova; I. V. Dubrovina; A. A. Burov; E. A. Filippova; V. V. Zubkov; L. V. Krechetova; V. V. Vtorushina; E. V. Inviyaeva; et al. (Bulletin of Experimental Biology and Medicine, 2022)

Comparative Efficacy of the Stromal-Vascular Fraction Cells of Lipoaspirate and Hyaluronic Acid in the Treatment of Gonarthrosis: Results of an Interim Analysis - E. Ya. Shevela; T. R. Glebova; M. A. Kotova; N. A. Nitsa; Yu. A. Kozhevnikov; I. V. Meledina; A. A. Ostanin; E. R. Chernykh (Bulletin of Experimental Biology and Medicine, 2022)

Expression of Inhibitory Molecules (Arginase-1, IDO, and PD-L1) by Myeloid-Derived Suppressor Cells in Multiple Myeloma Patients in Remission - T. V. Tyrinova; E. V. Batorov; T. A. Aristova; G. Yu. Ushakova; S. A. Sizikova; V. V. Denisova; A. A. Ostanin; E. R. Chernykh (Bulletin of Experimental Biology and Medicine, 2022)

A Method for Fluorescent Diagnosis of Malignant Cutaneous Neoplasms Using Ytterbium Phthalocyanines - D. D. Stavtsev; T. V. Dubinina; E. A. Gorbunova; A. Yu. Gerasimenko (Biomedical Engineering, 2022)

Circulating markers of oxidative stress and risk of incident cardiovascular events in obstructive sleep apnea - A. J. Hirsch Allen; Bernardo U. Peres; Yu Liu; Rachel Jen; Aditi Shah; Ismail Laher; Fernanda Almeida; Carolyn Taylor; Ali Abdul Ghafoor; Najib T. Ayas (Sleep and Biological Rhythms, 2022)

Changes in Electroencephalogram Indicators in Patients in the Somatogenic Phase of Acute Poisoning with Opioid Receptor Agonists - A. Yu. Mikhailov; I. Yu. Berezina; L. I. Sumsky; Yu.M. Scheidegger; T. A. Goretskaya; Yu.L. Arzumanov (Neuroscience and Behavioral Physiology, 2022)

Features of the Humoral Response to Infection, Vaccination, and Revaccination during COVID-19 - S. Yu. Kombarova; A. V. Aleshkin; L. I. Novikova; S. S. Bochkareva; A. M. Zatevalov; E. R. Mekhtiev; T. E. Mizaeva; A. A. Basov; O. Yu. Borisova; E. I. Likhanskaya; E. A. Voropaeva; Yu. N. Urban; et al. (Bulletin of Experimental Biology and Medicine, 2022)

Experimental Evaluation of the Effectiveness of Isobornylphenols in the Model of Pathospermia and Their Effect on the Antioxidant—Prooxidant Balance of Male Germ Cells - T. G. Borovskaya; A. V. Vychuzhanina; Yu. A. Shchemerova; E. V. Buravlev; I. Yu. Chukicheva; A. V. Kuchin (Bulletin of Experimental Biology and Medicine, 2022)

Acanthopagrus oconnorae , a new species of seabream (Sparidae) from the Red Sea - Lucía Pombo‐Ayora; Viktor N. Peinemann; Collin T. Williams; Song He; Yu Jia Lin; Yukio Iwatsuki; Donal D. C. Bradley; Michael L. Berumen (Journal of Fish Biology, 2022)
A new species of sparid fish, Acanthopagrus oconnorae , is described based on 11 specimens collected in the shallow (0–1 m depth) mangrove‐adjacent sandflats of Thuwal, Saudi Arabia. The new species is distinguished from its congeners by the following combination of characters: second anal‐fin spine 12.8%–16.6% of standard length (SL); 3½ scale rows between the fifth dorsal‐fin spine and lateral line; suborbital width 5.7%–6.7% of SL; eyes positioned at the anterior edge of the head, often forming a weakly convex break in an otherwise gently curved head profile, when viewed laterally; caudal fin light yellow with black posterior margin (approximately half of fin); anal fin dusky grey, with posterior one‐fifth of the fin light yellow; black streaks on inter‐radial membranes of anal fin absent. The most similar species to A. oconnorae is Acanthopagrus vagus , which differs by the presence of a w‐shaped anterior edge of the scaled predorsal area, a more acute snout and black streaks on the inter‐radial membranes of the anal fin. Phylogenetic placement and species delimitation of A. oconnorae are discussed based on COI, CytB and 16S sequences. It is hypothesized that ecology and behaviour explain how this species avoided detection despite its likely occurrence in coastal areas of the Red Sea with historically high fishing pressure.

Mild or Moderate COVID-19 during Pregnancy Does Not Affect the Content of CD34+ Hematopoietic Stem Cells in Umbilical Cord Blood of Newborns - Yu. A. Romanov; Yu. A. Kosolapova; V. V. Zubkov; D. N. Degtyarev; A. Yu. Romanov; T. N. Dugina; G. T. Sukhikh (Bulletin of Experimental Biology and Medicine, 2022)

Comparative analysis of four types of mesoscale eddies in the north pacific subtropical countercurrent region – part I spatial characteristics - Mengxuan An; Jie Liu; Jishan Liu; Wenjin Sun; Jingsong Yang; Wei Tan; Yu Liu; Kenny T. C. Lim Kam Sian; Jinlin Ji; Changming Dong (Frontiers in Marine Science, 2022)
The North Pacific Subtropical Countercurrent (STCC) region has high mesoscale eddy activities due to its complex circulation structure. This study divides these mesoscale eddies into four types: cyclonic cold-core eddy (CCE), anticyclonic warm-core eddy (AWE), cyclonic warm-core eddy (CWE), and anticyclonic cold-core eddy (ACE) according to the rotation direction of the eddy flow field and the sign of average temperature anomaly within the eddy after spatial high-pass filtering. CCE and ACE are called normal eddies, while CWE and ACE are named abnormal eddies. Using eddy-resolving model data (OFES), this work finds that the abnormal eddy phenomenon mainly occurs in the ocean’s upper layer. The eddy number proportion for CCEs, AWEs, CWEs, and ACEs at the sea surface is 35.60, 32.08, 12.95, and 19.37%. The corresponding average radius is 79.14 ± 3.7, 83.34 ± 3.75, 73.74 ± 4.14, and 79.46 ± 3.89 km, respectively. Each type of eddy’s average amplitude is about 3 cm. Regarding the eddy average eccentricity, the four types of eddies have very close eccentricities, with a range of 0.73 ~ 0.76. If the types of eddies are not distinguished, the eddies generated north of 21°N tend to move southward, while eddies generated south of that latitude tend to move northward. The depth of CCEs, AWEs, CWEs, and ACEs with average eddy nonlinearity larger than one is concentrated in the ocean’s upper layer at 109.0, 116.0, 159.0, and 52.0 m, respectively. This study deepens the understanding of the spatial distribution characteristics of mesoscale eddies in the STCC region.

Studies of Cognitive Functions and the Organization of Brain Bioelectrical Activity during Waking and Sleep in Patients with Frontal Lobe Tumors - Yu. Yu. Arapova; I. A. Popov; A. I. Shikhliarova; E. E. Rostorguev; N. S. Kuznetsova; T. P. Protasova (Neuroscience and Behavioral Physiology, 2022)

Modeling of Benign Prostatic Hyperplasia in Rats with a High Dose of Testosterone - I. V. Sorokina; N. A. Zhukova; Yu. V. Meshkova; D. S. Baev; T. G. Tolstikova; M. A. Bakarev; E. L. Lushnikova (Bulletin of Experimental Biology and Medicine, 2022)

Discerning Comparison of 1 and 0.5% Ethylene Glycol in Sprague-Dawley Rats with Modeled Urolithiasis - A. V. Bervinova; N. A. Borozdina; V. A. Palikov; Yu. A. Palikova; E. S. Mikhailov; I. N. Kravchenko; V. A. Rykov; T. I. Ponomareva; S. G. Semushina; I. A. Pakhomova; I. A. Dyachenko; A. N. Murashev (Bulletin of Experimental Biology and Medicine, 2022)

Infrared Thermometry for Acute Radiation Syndrome in Mice - Yu. A. Zrilova; T. M. Bychkova; Т. А. Karaulova; O. V. Nikitenko; I. M. Parfenova; N. M. Stavrakova; A. A. Ivanov (Bulletin of Experimental Biology and Medicine, 2022)

Psychopharmacological Effects of Stimulation of the Functions of Neural Stem Cells by STAT3 Inhibitor under Conditions of Modeled Ethanol-Induced Encephalopathy - G. N. Zyuz’kov; V. V. Zhdanov; L. A. Miroshnichenko; T. Yu. Polyakova; L. A. Stavrova; E. V. Simanina; M. Yu. Minakova; V. I. Agafonov; A. A. Churin (Bulletin of Experimental Biology and Medicine, 2022)

Parameters of Hemodynamic Allostasis in Patients of Various Age Groups with Essential Arterial Hypertension - T. Yu. Zotova; A. A. Lukanina; M. L. Blagonravov (Bulletin of Experimental Biology and Medicine, 2022)

In-situ radon-in-water detection for high resolution submarine groundwater discharge assessment - Shibin Zhao; Meng Li; William C. Burnett; Kai Cheng; Chunqian Li; Jinjia Guo; Songling Yu; Wen Liu; Tong Yang; Natasha T. Dimova; Guangquan Chen; Zhigang Yu; et al. (Frontiers in Marine Science, 2022)
Submarine groundwater discharge (SGD), including both land-based fresh groundwater that enters the ocean from coastal aquifers as well as recirculated seawater that is continuously recharged and discharged on the seabed, has been considered as an important component of the global water and biogenic element (e.g., nitrogen, phosphorus, silicon and carbon) sources and a significant pathway for material exchange at the land-sea interface of coastal ecosystems. Some researchers reported that SGD associated nutrient additions to coastal waters have caused unwanted ecological issues, including red tides, coastal acidification and hypoxia. Natural radon isotope ( 222 Rn, t 1/2 = 3.8 d ) is an excellent tracer for studying SGD and other oceanographic processes including air-sea gas exchange, sediment-water diffusion, and earthquake prediction. However, the conventional radon measurement methods suffer many technical disadvantages. We consequently developed a convenient submersible radon determination approach (“OUC-Rn”) using a commercial pulsed ionization chamber (PIC) radon sensor and gas extraction membrane module to produce high precision and high resolution observations. We demonstrate the radon degassing efficiency of the membrane contactor is comparable to the shower-head type air-water exchanger but is independent of operating position. The radon measurement efficiency of the PIC is 2-fold higher than the RAD7 detector and is far less influenced by moisture. We successfully deployed the system in 2.5 meters water depth over a 100 hours period in an anthropogenic influenced bay. Based on our high temporal resolution observations, the SGD flux was estimated to be 0-43.0 cm/d (mean: 25.4 ± 14.5 cm/d). The SGD fluxes pattern plotted together with the tidal variations revealed that tidal pumping may be the main force driving seawater recirculation into aquifers and thus affecting nutrient, carbon and other dissolved matters dynamics in coastal regions.

Machine learning methods for assessing photosynthetic activity: environmental monitoring applications - S. S. Khruschev; T. Yu. Plyusnina; T. K. Antal; S. I. Pogosyan; G. Yu. Riznichenko; A. B. Rubin (Biophysical Reviews, 2022)

GeoSoilEnviroCARS (Sector 13) at the Advanced Photon Source: a comprehensive synchrotron radiation facility for Earth science research at ambient and extreme conditions - S. R. Sutton; M. L. Rivers; S. Chariton; P. J. Eng; A. Lanzirotti; M. Newville; T. Officer; V. B. Prakapenka; Y. J. Ryu; J. E. Stubbs; S. Tkachev; Y. Wang; et al. (Physics and Chemistry of Minerals, 2022)

Antimicrobial Activity of the Serum before and after Vaccination with EpiVacCorona - V. G. Arzumanyan; E. P. Bystritskaya; T. I. Kolyganova; A. M. Iksanova; P. V. Samoilikov; S. Yu. Konanykhina; A. A. Vartanova; O. A. Svitich (Bulletin of Experimental Biology and Medicine, 2022)

Delayed Consequences of the Toxic Effect of Paclitaxel on the Testes of Prepubertal Rats and Their Correction with p-Tyrosol - T. G. Borovskaya; V. A. Grigor’eva; Yu. A. Shchemerova; E. A. Bokhan; A. V. Vychuzhanina; S. I. Kamalova; V. E. Goldberg (Bulletin of Experimental Biology and Medicine, 2022)

A Mathematical Model of a Thermoelectric Device for the Treatment of Whitlow by Local Hypothermia - O. V. Yevdulov; D. V. Yevdulov; T. I. Isabekova; G. I. Aminov; I. Yu. Aminova (Biomedical Engineering, 2022)

A Warm and A Cold Spot in Cape Cod Waters Amid the Recent New England Shelf Warming - Lisan Yu; Kristine T. Yang (Frontiers in Marine Science, 2022)
Despite the widely recognized warming of the New England Continental Shelf (NES), climate patterns of the shelf’s economically and ecologically important coastal environments remain less examined. Here we use a satellite sea-surface temperature (SST) analysis gridded on 0.05°C spatial resolution to show, for the first time, the existence of a warm and a cold spot in the environs of Cape Cod, Massachusetts amid the NES warming of the past 15 years. The warm spot refers to an increasing warming trend in shallow waters of Nantucket Sound sheltered by the islands of Martha’s Vineyard and Nantucket. The summer SST maxima have increased by 3.1±1.0°C ( p<0.1 ), about three times faster than the warming elsewhere on the NES, and the summer season has lengthened by 20 ± 7 days ( p<0.1 ). The cold spot refers to an increasing cooling trend over Nantucket Shoals, an area of shallow sandy shelf that extends south and southeast from Nantucket Island and also known for strong tidal mixing. The strong cooling trend during June–August reduced the SST maxima by -2.5±1.2°C ( p<0.1 ) and shortened the warm season by -32 ± 11 days ( p<0.1 ). Away from the Cape Cod waters, the broad warming on the shelf is attributable to a forward shifted annual cycle. The shift is most significant in August–November, during which the summer temperatures lingered longer into the fall, producing a pronounced warming and delaying the onset of the fall season by 13 ± 6 days ( p<0.1 ). The three different patterns of SST phenology trends displayed by the respective warm spot, the cold spot, and the broad shelf highlight the highly dynamically diverse responses of coastal waters under climate warming. Finally, the study showed that spatial resolution of SST datasets affects the characterization of the spatial heterogeneity in the nearshore SSTs. The widely used Optimum Interpolation SST (OISST) on 0.25°C resolution was examined. Although the two SST datasets agree well with the measurements from the moored buoys at four locations, OISST does not have the cold spot and shows a higher rate of warming on the shelf.

Studies of the Relationship between Oxytocinergic System Genes, Perinatal Complications, and the Formation of Interpersonal Relationships in Schizophrenia Patients - V. A. Mikhailova; T. V. Lezheiko; N. Yu. Kolesina; V. E. Golimbet (Neuroscience and Behavioral Physiology, 2022)

Developing machine learning model to estimate the shear capacity for RC beams with stirrups using standard building codes - Md Nasir Uddin; Kequan Yu; Ling-zhi Li; Junhong Ye; T. Tafsirojjaman; Wael Alhaddad (Innovative Infrastructure Solutions, 2022)

Prediction of disability-free survival in healthy older people - Johannes Tobias Neumann; Le T. P. Thao; Anne M. Murray; Emily Callander; Prudence R. Carr; Mark R. Nelson; Rory Wolfe; Robyn L. Woods; Christopher M. Reid; Raj C. Shah; Anne B. Newman; Jeff D. Williamson; et al. (GeroScience, 2022)
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disability-free survival outcome was defined as absence of dementia, persistent disability or death. Selection of potential predictors from amongst 25 biomedical, psychosocial and lifestyle variables including recognized geriatric risk factors, utilizing a machine-learning approach. Separate models were developed for men and women. The selected predictors were evaluated in a multivariable Cox proportional hazards model and validated internally by bootstrapping. We included 19,114 Australian and US participants aged ≥65 years (median 74 years, IQR 71.6–77.7). Common predictors of a worse prognosis in both sexes included higher age, lower Modified Mini-Mental State Examination score, lower gait speed, lower grip strength and abnormal (low or elevated) body mass index. Additional risk factors for men included current smoking, and abnormal eGFR. In women, diabetes and depression were additional predictors. The biased-corrected areas under the receiver operating characteristic curves for the final prognostic models at 5 years were 0.72 for men and 0.75 for women. Final models showed good calibration between the observed and predicted risks. We developed a prediction model in which age, cognitive function and gait speed were the strongest predictors of disability-free survival in healthy older people. Trial registration Clinicaltrials.gov (NCT01038583)

Search for New Target Genes of MicroRNA for Differential Diagnosis of Benign and Malignant Neoplasms of the Thyroid Gland by In Silico Methods - V. V. Kononchuk; E. V. Kopeikina; T. S. Kalinina; O. V. Saik; E. Yu. Alekseenok; M. K. Kolyagina; V. A. Matashova; S. P. Shevchenko; L. F. Gulyaeva; N. E. Kushlinskii (Bulletin of Experimental Biology and Medicine, 2022)

Erythropoiesis-Stimulating Properties of Anthocyanin-Containing Complex from Sorbus aucuparia L. in Cytostatic Anemic Syndrome in Mice with Lewis Lung Carcinoma - O. Yu. Rybalkina; E. P. Fedorova; A. V. Chaikovsky; T. G. Razina; G. I. Kalinkina; N. V. Isaikina; E. A. Kiseleva; E. P. Zueva; V. V. Zhdanov (Bulletin of Experimental Biology and Medicine, 2022)

Prognostication of Functional Outcomes of Schizophrenia Using a Multigene Panel - S. A. Golubev; T. V. Lezheiko; G. I. Korovaitseva; M. V. Gabaeva; N. Yu. Kolesina; V. G. Kaleda; V. E. Golimbet (Neuroscience and Behavioral Physiology, 2022)

A Laser Technology for Producing Conductive Film and Bulk Composites Based on Calcium Phosphate and Carbon Nanotubes for Bone Tissue Engineering - D. T. Murashko; S. Z. Zhovnir; M. S. Savelyev; A. Yu. Fedotov; P. V. Lobzhanidze; E. P. Kitsyuk (Biomedical Engineering, 2022)

Numerical Studies of Polymer Materials with Potential for Use in Coronary Stent-Grafts - K. Yu. Klyshnikov; M. A. Rezvova; T. V. Glushkova; Yu. A. Kudryavtseva; E. A. Ovcharenko (Biomedical Engineering, 2022)

Global maps of soil temperature - Jonas J. Lembrechts; Johan van den Hoogen; Juha Aalto; Michael B. Ashcroft; Pieter De Frenne; Julia Kemppinen; Martin Kopecký; Miska Luoto; Ilya M. D. Maclean; Thomas W. Crowther; Joseph J. Bailey; Stef Haesen; et al. (Global Change Biology, 2022)
Research in global change ecology relies heavily on global climatic grids derived from estimates of air temperature in open areas at around 2 m above the ground. These climatic grids do not reflect conditions below vegetation canopies and near the ground surface, where critical ecosystem functions occur and most terrestrial species reside. Here, we provide global maps of soil temperature and bioclimatic variables at a 1‐km 2 resolution for 0–5 and 5–15 cm soil depth. These maps were created by calculating the difference (i.e. offset) between in situ soil temperature measurements, based on time series from over 1200 1‐km 2 pixels (summarized from 8519 unique temperature sensors) across all the world's major terrestrial biomes, and coarse‐grained air temperature estimates from ERA5‐Land (an atmospheric reanalysis by the European Centre for Medium‐Range Weather Forecasts). We show that mean annual soil temperature differs markedly from the corresponding gridded air temperature, by up to 10°C (mean = 3.0 ± 2.1°C), with substantial variation across biomes and seasons. Over the year, soils in cold and/or dry biomes are substantially warmer (+3.6 ± 2.3°C) than gridded air temperature, whereas soils in warm and humid environments are on average slightly cooler (−0.7 ± 2.3°C). The observed substantial and biome‐specific offsets emphasize that the projected impacts of climate and climate change on near‐surface biodiversity and ecosystem functioning are inaccurately assessed when air rather than soil temperature is used, especially in cold environments. The global soil‐related bioclimatic variables provided here are an important step forward for any application in ecology and related disciplines. Nevertheless, we highlight the need to fill remaining geographic gaps by collecting more in situ measurements of microclimate conditions to further enhance the spatiotemporal resolution of global soil temperature products for ecological applications.

Influence of KAR1 on the plant growth and development of dormant seeds by balancing different factors - A. Sami; Z. H. Zhu; T. X. Zhu; D. M. Zhang; L. H. Xiao; Y. Yu; K. J. Zhou (International Journal of Environmental Science and Technology, 2022)

DVPred: a disease-specific prediction tool for variant pathogenicity classification for hearing loss - Fengxiao Bu; Mingjun Zhong; Qinyi Chen; Yumei Wang; Xia Zhao; Qian Zhang; Xiarong Li; Kevin T. Booth; Hela Azaiez; Yu Lu; Jing Cheng; Richard J. H. Smith; et al. (Human Genetics, 2022)

Panel of Candidate Genes to Predict the Survival of Patients with Clear Cell Renal Cancer on the Basis of Gene Expression Regulated by HIF1α/HIF2α - N. V. Apanovich; P. V. Apanovich; D. J. Mansorunov; A. Yu. Kuzevanova; A. A. Korotaeva; T. A. Bogush; V. B. Matveev; A. V. Karpukhin (Bulletin of Experimental Biology and Medicine, 2022)

The Role of JAK and STAT3 in Regulation of Secretory Function of Neuroglial Cells of Different Types in Ethanol-Induced Neurodegenerationt - G. N. Zyuz’kov; V. V. Zhdanov; L. A. Miroshnichenko; T. Yu. Polyakova; E. V. Simanina; M. G. Danilets; M. Yu. Minakova; A. A. Churin; V. I. Agafonov (Bulletin of Experimental Biology and Medicine, 2022)

Correction to: Allochromatium tepidum, sp. nov., a hot spring species of purple sulfur bacteria - Michael T. Madigan; Jill N. Absher; Joseph E. Mayers; Marie Asao; Deborah O. Jung; Kelly S. Bender; Megan L. Kempher; Mackenzie K. Hayward; Sophia A. Sanguedolce; Abigail C. Brown; Shinichi Takaichi; Ken Kurokawa; et al. (Archives of Microbiology, 2022)

New type of RNA virus replication inhibitor based on decahydro-closo-decaborate anion containing amino acid ester pendant group - Varvara V. Avdeeva; Timur M. Garaev; Natalia V. Breslav; Elena I. Burtseva; Tatyana V. Grebennikova; Andrei P. Zhdanov; Konstantin Yu. Zhizhin; Elena A. Malinina; Nikolay T. Kuznetsov (JBIC Journal of Biological Inorganic Chemistry, 2022)

Molecular and Clinical Aspects of the Action of Cytidine Diphosphocholine on Cognitive Functions - O. A. Gromova; I. Yu. Torshin; T. R. Grishina; V. I. Demidov; T. E. Bogacheva (Neuroscience and Behavioral Physiology, 2022)

Landscape REE anomalies and the cause of geophagy in wild animals at kudurs (mineral salt licks) in the Sikhote-Alin (Primorsky Krai, Russia) - A. M. Panichev; N. V. Baranovskaya; I. V. Seryodkin; I. Yu. Chekryzhov; E. A. Vakh; B. R. Soktoev; A. I. Belyanovskaya; R. A. Makarevich; T. N. Lutsenko; N. Yu. Popov; A. V. Ruslan; D. S. Ostapenko; et al. (Environmental Geochemistry and Health, 2022)

Gene expression regulating the cell cycle and gene of antioxidant protection system in toxic hepatitis - Y. V. Valova; M. M. Ziatdinova; G. F. Mukhammadieva; D. O. Karimov; A. S. Fazlyeva; N. Yu. Khusnutdinova; T. G. Yakupova; E. F. Repina (Toxicology and Environmental Health Sciences, 2022)

Estimation of the Regenerative Potential of para-Tyrosol in the Model of Testicular Insufficiency Caused by Damage to Spermatogonial Stem Cells - T. G. Borovskaya; V. A. Grigor’eva; Yu. A. Shchemerova; S. I. Kamalova; A. V. Vychuzhanina; N. A. Krivova; O. B. Zaeva; V. E. Goldberg; A. M. Dygai (Bulletin of Experimental Biology and Medicine, 2022)

The influence of aboveground and belowground species composition on spatial turnover in nutrient pools in alpine grasslands - Xin Jing; Case M. Prager; Litong Chen; Haiyan Chu; Nicholas J. Gotelli; Jin‐Sheng He; Yu Shi; Teng Yang; Biao Zhu; Aimée T. Classen; Nathan J. Sanders (Global Ecology and Biogeography, 2022)
Aim An important research question in ecology is how climate and the biodiversity of aboveground plants and belowground microbiomes affect ecosystem functions such as nutrient pools. However, little is studied on the concurrent role of above‐ and belowground species composition in shaping the spatial distribution patterns of ecosystem functions across environmental gradients. Here, we investigated the relationships between the taxonomic composition of plants, soil bacteria and soil fungi and spatial turnover in nutrient pools, and assessed how species composition–nutrient pool relationships were mediated by contemporary climatic conditions. Location Qinghai‐Tibetan Plateau. Time period Current. Major taxa studied Plants, soil bacteria and soil fungi. Methods We surveyed plant assemblages, sampled the taxonomic composition of soil bacteria and soil fungi, and measured plant‐ and soil‐mediated nutrient pools at 60 alpine grasslands on the Qinghai‐Tibetan Plateau. Using Mantel tests, structural equation models and general linear models, we investigated the relative importance of the taxonomic composition of plant, soil bacterial, and soil fungal communities on the spatial turnover of alpine grassland nutrient pools. Results We found that the taxonomic composition of plant, soil bacterial, and soil fungal communities was associated with local climate. However, the effects of local climate on the spatial turnover of plant‐ and soil‐mediated nutrient pools were mainly indirect and mediated through plant and soil bacterial species composition, but not through soil fungal species composition. We further found that the replacement component of soil bacterial β‐diversity and the richness difference of plant β‐diversity were the direct predictors of nutrient pools in the alpine grasslands. Main conclusions These results highlight that belowground bacterial composition together with aboveground plant species composition are related to spatial turnover in nutrient pools, perhaps even driving it. Conserving above‐ and belowground biodiversity may therefore safeguard against the impacts of local climate on the functions of climate‐sensitive alpine grasslands.

Micromechanical behaviors and fabric within the immediate influence zone of granular-continuum interfaces - Nan Zhang; Shiwei Zhao; T. Matthew Evans; Yu Du; Yushun Lian (European Journal of Environmental and Civil Engineering, 2022)

Population Genomics, Transcriptional Response to Heat Shock, and Gut Microbiota of the Hong Kong Oyster Magallana hongkongensis - Yichun Xie; Elaine Y. Y. Huang; Wenyan Nong; Sean T. S. Law; Yifei Yu; Khan Cheung; Yiqian Li; Cheuk Fung Wong; Ho Yin Yip; Patrick W. S. Joyce; King Ming Chan; Ka Hou Chu; et al. (Journal of Marine Science and Engineering, 2022)
The Hong Kong oyster Magallana hongkongensis, previously known as Crassostrea hongkongensis, is a true oyster species native to the estuarine-coast of the Pearl River Delta in southern China. The species—with scientific, ecological, cultural, and nutritional importance—has been farmed for hundreds of years. However, there is only limited information on its genetics, stress adaptation mechanisms, and gut microbiota, restricting the sustainable production and use of oyster resources. Here, we present population structure analysis on M. hongkongensis oysters collected from Deep Bay and Lantau Island in Hong Kong, as well as transcriptome analysis on heat shock responses and the gut microbiota profile of M. hongkongensis oysters collected from Deep Bay. Single nucleotide polymorphisms (SNPs), including those on the homeobox genes and heat shock protein genes, were revealed by the whole genome resequencing. Transcriptomes of oysters incubated at 25 °C and 32 °C for 24 h were sequenced which revealed the heat-induced regulation of heat shock protein pathway genes. Furthermore, the gut microbe community was detected by 16S rRNA sequencing which identified Cyanobacteria, Proteobacteria and Spirochaetes as the most abundant phyla. This study reveals the molecular basis for the adaptation of the oyster M. hongkongensis to environmental conditions.

Correlation between Structural Transformations in Mesenteric Lymph Nodes and the Levels MicroRNA during Polychemotherapy of Breast Cancer - A. V. Kabakov; O. V. Kazakov; A. F. Poveshchenko; A. P. Lykov; T. V. Raiter; D. N. Strunkin; L. F. Gulyaeva; V. I. Konenkov; A. Yu. Letyagin (Bulletin of Experimental Biology and Medicine, 2022)

Complete genome of the thermophilic purple sulfur Bacterium Thermochromatium tepidum compared to Allochromatium vinosum and other Chromatiaceae - W. Matthew Sattley; Wesley D. Swingley; Brad M. Burchell; Emma D. Dewey; Mackenzie K. Hayward; Tara L. Renbarger; Kathryn N. Shaffer; Lynn M. Stokes; Sonja A. Gurbani; Catrina M. Kujawa; D. Adam Nuccio; Jacob Schladweiler; et al. (Photosynthesis Research, 2022)

Impairments to Executive Functions in Children with Dyslexia - L. S. Chutko; S. Yu. Surushkina; E. A. Yakovenko; T. I. Anisimova; M. D. Didur; S. A. Chekalova (Neuroscience and Behavioral Physiology, 2022)

Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation - R. J. Longchamps; S. Y. Yang; C. A. Castellani; W. Shi; J. Lane; M. L. Grove; T. M. Bartz; C. Sarnowski; C. Liu; K. Burrows; A. L. Guyatt; T. R. Gaunt; et al. (Human Genetics, 2022)
Mitochondrial DNA copy number (mtDNA-CN) measured from blood specimens is a minimally invasive marker of mitochondrial function that exhibits both inter-individual and intercellular variation. To identify genes involved in regulating mitochondrial function, we performed a genome-wide association study (GWAS) in 465,809 White individuals from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium and the UK Biobank (UKB). We identified 133 SNPs with statistically significant, independent effects associated with mtDNA-CN across 100 loci. A combination of fine-mapping, variant annotation, and co-localization analyses was used to prioritize genes within each of the 133 independent sites. Putative causal genes were enriched for known mitochondrial DNA depletion syndromes ( p = 3.09 × 10 –15 ) and the gene ontology (GO) terms for mtDNA metabolism ( p = 1.43 × 10 –8 ) and mtDNA replication ( p = 1.2 × 10 –7 ). A clustering approach leveraged pleiotropy between mtDNA-CN associated SNPs and 41 mtDNA-CN associated phenotypes to identify functional domains, revealing three distinct groups, including platelet activation, megakaryocyte proliferation, and mtDNA metabolism. Finally, using mitochondrial SNPs, we establish causal relationships between mitochondrial function and a variety of blood cell-related traits, kidney function, liver function and overall ( p = 0.044) and non-cancer mortality ( p = 6.56 × 10 –4 ).

Effects of Boron Neutron Capture Therapy on the Growth of Subcutaneous Xenografts of Human Colorectal Adenocarcinoma SW-620 in Immunodeficient Mice - V. V. Kanygin; A. I. Kasatova; E. L. Zavjalov; I. A. Razumov; S. I. Kolesnikov; A. I. Kichigin; O. I. Solov’eva; A. R. Tsygankova; S. Yu. Taskaev; D. A. Kasatov; T. V. Sycheva; V. A. Byvaltsev (Bulletin of Experimental Biology and Medicine, 2022)

Allochromatium tepidum, sp. nov., a hot spring species of purple sulfur bacteria - Michael T. Madigan; Jill N. Absher; Joseph E. Mayers; Marie Asao; Deborah O. Jung; Kelly S. Bender; Megan L. Kempher; Mackenzie K. Hayward; Sophia A. Sanguedolce; Abigail C. Brown; Shinichi Takaichi; Ken Kurokawa; et al. (Archives of Microbiology, 2022)

Excipient Innovation Through Precompetitive Research - Yihua Bruce Yu; Marc B. Taraban; Katharine T. Briggs; Robert G. Brinson; John P. Marino (Pharmaceutical Research, 2021)

Bioinformatic analyses suggest augmented interleukin-17 signaling as the mechanism of COVID-19-associated herpes zoster - Xin Yu; Linfeng Li; Matthew T. V. Chan; William Ka Kei Wu (Environmental Science and Pollution Research, 2021)

Inhibitors of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (Statins) Suppress Proliferation and Motility of Human CD4+ T Lymphocytes in Culture - N. V. Radyukhina; N. Yu. Ruleva; A. Yu. Filatova; T. I. Aref’eva (Bulletin of Experimental Biology and Medicine, 2021)

Influence of Extracellular Vesicles of the Follicular Fluid on Morphofunctional Characteristics of Human Sperm - A. P. Sysoeva; N. P. Makarova; D. N. Silachev; N. N. Lobanova; Yu. A. Shevtsova; E. E. Bragina; E. A. Kalinina; G. T. Sukhikh (Bulletin of Experimental Biology and Medicine, 2021)

Fan-delta facies architecture, morphological evolution and sediment delivery in the Oligocene Dongying Formation of the Nanpu Sag, Bohai Bay Basin, China - H. Jia; T. Liu; H. Ji; X. Meng; J. Yu (Australian Journal of Earth Sciences, 2021)

Optimizing the Design of Blood–Brain Barrier-Penetrating Polymer-Lipid-Hybrid Nanoparticles for Delivering Anticancer Drugs to Glioblastoma - Taksim Ahmed; Fuh-Ching Franky Liu; Chungsheng He; Azhar Z. Abbasi; Ping Cai; Andrew M. Rauth; Jeffery T. Henderson; Xiao Yu Wu (Pharmaceutical Research, 2021)

Leading cancers contributing to educational disparities in cancer mortality in the US, 2017 - Diana R. Withrow; Neal D. Freedman; James T. Gibson; Mandi Yu; Anna M. Nápoles; Amy Berrington de González; Meredith S. Shiels (Cancer Causes & Control, 2021)
Purpose To inform prevention efforts, we sought to determine which cancer types contribute the most to cancer mortality disparities by individual-level education using national death certificate data for 2017. Methods Information on all US deaths occurring in 2017 among 25–84-year-olds was ascertained from national death certificate data, which include cause of death and educational attainment. Education was classified as high school or less (≤ 12 years), some college or diploma (13–15 years), and Bachelor's degree or higher (≥ 16 years). Cancer mortality rate differences (RD) were calculated by subtracting age-adjusted mortality rates (AMR) among those with ≥ 16 years of education from AMR among those with ≤ 12 years. Results The cancer mortality rate difference between those with a Bachelor's degree or more vs. high school or less education was 72 deaths per 100,000 person-years. Lung cancer deaths account for over half (53%) of the RD for cancer mortality by education in the US. Conclusion Efforts to reduce smoking, particularly among persons with less education, would contribute substantially to reducing educational disparities in lung cancer and overall cancer mortality.

Microbial communities associated with the ostracods Candona sp. inhabiting the area of the methane seep Goloustnoye (Lake Baikal) - I. A. Khalzov; S. V. Bukin; A. S. Zakharenko; S. M. Chernitsyna; Yu. P. Galachyants; T. Ya. Sitnikova; T. I. Zemskaya (Symbiosis, 2021)

Colony-Forming Ability and Residual Foci of DNA Repair Proteins in Human Lung Fibroblasts Irradiated with Subpicosecond Beams of Accelerated Electrons - N. S. Babayan; D. V. Guryev; N. Yu. Vorobyeva; B. A. Grigoryan; G. L. Tadevosyan; L. S. Apresyan; A. K. Chigasova; E. I. Yashkina; S. M. Rodneva; A. A. Tsishnatti; Yu. A. Fedotov; N. K. Sarkisyan; et al. (Bulletin of Experimental Biology and Medicine, 2021)

Association between Molecular Genetic Markers of DNA Repair and Cell Cycle Control Genes and Response to Platinum-Based Chemotherapy in Ovarian Cancer Patients - T. M. Zavarikina; S. V. Khokhlova; A. S. Tyulyandina; G. N. Khabas; A. V. Asaturova; Yu. V. Nosova; P. K. Brenner; M. A. Kapralova; D. S. Khodirev; M. B. Stenina (Bulletin of Experimental Biology and Medicine, 2021)

Role of MAPK ERK1/2 and p38 in the Regulation of Secretory Functions of Different Populations of Neuroglia in Ethanol-Induced Neurodegeneration - G. N. Zyuz’kov; L. A. Miroshnichenko; T. Yu. Polyakova; V. V. Zhdanov; E. V. Simanina; L. A. Stavrova; A. A. Churin; T. I. Fomina (Bulletin of Experimental Biology and Medicine, 2021)

Study of the Dynamics of Biofilm Formation and Elastase Activity of Pseudomonas aeruginosa in the Presence of Dodecanoyl-Homoserine Lactone - V. S. Cherepushkina; T. E. Mironova; V. N. Afonyushkin; V. Yu. Koptev; E. V. Nefedova; N. A. Donchenko; A. S. Dimova (Bulletin of Experimental Biology and Medicine, 2021)

Age-Related Features of the Viscosity of Plasma and Mitochondrial Membranes of Hepatocytes in Liver Cirrhosis - E. G. Skurikhin; S. A. Afanas’ev; M. A. Zhukova; T. Yu. Rebrova; E. F. Muslimova; E. S. Pan; N. N. Ermakova; O. V. Pershina; A. V. Pakhomova; O. D. Putrova; L. A. Sandrikina; L. V. Kogai; et al. (Bulletin of Experimental Biology and Medicine, 2021)

Antibodies from Multiple Sclerosis Brain Identified Epstein-Barr Virus Nuclear Antigen 1 & 2 Epitopes which Are Recognized by Oligoclonal Bands - Zhe Wang; Peter GE Kennedy; Cecily Dupree; Min Wang; Catherin Lee; Tiffany Pointon; T. Dianne Langford; Michael W Graner; Xiaoli Yu (Journal of Neuroimmune Pharmacology, 2021)

Genetic analyses of gynecological disease identify genetic relationships between uterine fibroids and endometrial cancer, and a novel endometrial cancer genetic risk region at the WNT4 1p36.12 locus - Pik Fang Kho; Sally Mortlock; Frederic Amant; Daniela Annibali; Katie Ashton; John Attia; Paul L. Auer; Matthias W. Beckmann; Amanda Black; Louise Brinton; Daniel D. Buchanan; Stephen J. Chanock; et al. (Human Genetics, 2021)

The Role of Intracellular Signaling Molecules in the Production of Granulocytic CSF Mononuclear Phagocytes in Stress and Cytostatic Influence - V. V. Zhdanov; L. A. Miroshnichenko; G. N. Zyuz’kov; T. Yu. Khrichkova; E. V. Udut; E. V. Simanina; E. Yu. Sherstoboev; L. A. Stavrova; V. I. Agafonov; M. G. Danilets; E. S. Trofimova; M. Yu. Minakova; et al. (Bulletin of Experimental Biology and Medicine, 2021)

Effect of 4-Hexylresorcinol on the Efficiency of Antibiotic Treatment of Experimental Sepsis Caused by Antibiotic-Resistant Klebsiella pneumoniae Strain in Mice - I. G. Shemyakin; O. Yu. Manzenyuk; G. I. El’-Registan; V. V. Firstova; T. I. Kombarova; T. Yu. Gneusheva; E. I. Kyazimov; Yu. A. Nikolaev (Bulletin of Experimental Biology and Medicine, 2021)

Involvement of Hypothalamo-Hypophyseal-Adrenocortical System Hormones in Gastroprotection in Rats on Sensitization and Desensitization of Capsaicin-Sensitive Afferent Neurons - T. T. Podvigina; O. Yu. Morozova; O. P. Komkova; L. P. Filaretova (Neuroscience and Behavioral Physiology, 2021)

Roundup negatively impacts the behavior and nerve function of the Madagascar hissing cockroach (Gromphadorhina portentosa) - Megha Kanabar; Samuel Bauer; Zimuzo M. Ezedum; Ian P. Dwyer; William S. Moore; Gabriella Rodriguez; Aditya Mall; Anne T. Littleton; Michael Yudell; Jenil Kanabar; Wade J. Tucker; Emily R. Daniels; et al. (Environmental Science and Pollution Research, 2021)

Role of JNK and p53 in Implementation of Functions of Various Types of Regeneration-Competent Cells of the Nervous Tissue - G. N. Zyuz’kov; V. V. Zhdanov; L. A. Miroshnichenko; T. Yu. Polyakova; E. V. Simanina; L. A. Stavrova; M. G. Danilets; V. I. Agafonov; A. V. Chaikovskii (Bulletin of Experimental Biology and Medicine, 2021)

Saturation of thylakoid‐associated fatty acids facilitates bioenergetic coupling in a marine diatom allowing for thermal acclimation - Kuan Yu Cheong; Emre Firlar; Lia Ficaro; Maxim Y. Gorbunov; Jason T. Kaelber; Paul G. Falkowski (Global Change Biology, 2021)
In a rapidly warming world, we ask, “What limits the potential of marine diatoms to acclimate to elevated temperatures?,” a group of ecologically successful unicellular eukaryotic photoautotrophs that evolved in a cooler ocean and are critical to marine food webs. To this end, we examined thermal tolerance mechanisms related to photosynthesis in the sequenced and transformable model diatom Phaeodactylum tricornutum . Data from transmission electron microscopy (TEM) and fatty acid methyl ester‐gas chromatography mass spectrometry (FAME‐GCMS) suggest that saturating thylakoid‐associated fatty acids allowed rapid (on the order of hours) thermal tolerance up to 28.5°C. Beyond this critical temperature, thylakoid ultrastructure became severely perturbed. Biophysical analyses revealed that electrochemical leakage through the thylakoid membranes was extremely sensitive to elevated temperature (Q 10 of 3.5). Data suggest that the loss of the proton motive force (pmf) occurred even when heat‐labile photosystem II (PSII) was functioning, and saturation of thylakoid‐associated fatty acids was active. Indeed, growth was inhibited when leakage of pmf through thylakoid membranes was insufficiently compensated by proton input from PSII. Our findings provide a mechanistic understanding of the importance of rapid saturation of thylakoid‐associated fatty acids for ultrastructure maintenance and a generation of pmf at elevated temperatures. To the extent these experimental results apply, the ability of diatoms to generate a pmf may be a sensitive parameter for thermal sensitivity diagnosis in phytoplankton.

Novel disease resistance gene paralogs created by CRISPR/Cas9 in soy - Ervin D. Nagy; Julia L. Stevens; Neil Yu; Chris S. Hubmeier; Nona LaFaver; Megan Gillespie; Brian Gardunia; Qianshun Cheng; Steven Johnson; Audrey L. Vaughn; Miguel E. Vega-Sanchez; Mingqui Deng; et al. (Plant Cell Reports, 2021)
Key message Novel disease resistance gene paralogues are generated by targeted chromosome cleavage of tandem duplicated NBS-LRR gene complexes and subsequent DNA repair in soybean. This study demonstrates accelerated diversification of innate immunity of plants using CRISPR. Abstract Nucleotide-binding-site-leucine-rich-repeat (NBS-LRR) gene families are key components of effector-triggered immunity. They are often arranged in tandem duplicated arrays in the genome, a configuration that is conducive to recombinations that will lead to new, chimeric genes. These rearrangements have been recognized as major sources of novel disease resistance phenotypes. Targeted chromosome cleavage by CRISPR/Cas9 can conceivably induce rearrangements and thus emergence of new resistance gene paralogues. Two NBS-LRR families of soy have been selected to demonstrate this concept: a four-copy family in the Rpp1 region (Rpp1L) and a large, complex locus, Rps1 with 22 copies. Copy-number variations suggesting large-scale, CRISPR/Cas9-mediated chromosome rearrangements in the Rpp1L and Rps1 complexes were detected in up to 58.8% of progenies of primary transformants using droplet-digital PCR. Sequencing confirmed development of novel, chimeric paralogs with intact open reading frames. These novel paralogs may confer new disease resistance specificities. This method to diversify innate immunity of plants by genome editing is readily applicable to other disease resistance genes or other repetitive loci.

Severity of Neurotic Disorders and Social Masochism in Chemical Addicts - C. P. Korolenko; A. A. Ovchinnikov; A. N. Sultanova; T. Yu. Sycheva; T. A. Shpiks; E. V. Tagiltseva (Neuroscience and Behavioral Physiology, 2021)

The Role of Systemic Inflammation in the Pathogenesis of Hemorrhagic Stroke in the Presence and Absence of Effective Brain Blood Flow - P. Yu. Bochkarev; O. V. Berdyugina; V. S. Zhidkova; T. E. Zubova; E. Yu. Gusev (Neuroscience and Behavioral Physiology, 2021)

Circular dichroism and resonance Raman spectroscopies of bacteriochlorophyll b-containing LH1-RC complexes - Y. Kimura; T. Yamashita; R. Seto; M. Imanishi; M. Honda; S. Nakagawa; Y. Saga; S. Takenaka; L.-J. Yu; M. T. Madigan; Z.-Y. Wang-Otomo (Photosynthesis Research, 2021)