Corrigendum to “Induction of core symptoms of autism spectrum disorders by in vivo CRISPR/Cas9-based gene editing in the brain of adolescent rhesus monkeys” [Sci. Bull. 66(9) (2021) 937–946] - Shi-Hao Wu; Xiao Li; Dong-Dong Qin; Lin-Heng Zhang; Tian-Lin Cheng; Zhi-Fang Chen; Bin-Bin Nie; Xiao-Feng Ren; Jing Wu; Wen-Chao Wang; Ying-Zhou Hu; Yi-lin Gu; et al. (Science Bulletin, 2023)

Quantification of the uncertainty in multiscale validation of coarse-resolution satellite albedo products: A study based on airborne CASI data - Xiaodan Wu; Jianguang Wen; Rongqi Tang; Jingping Wang; Qicheng Zeng; Zheng Li; Dongqin You; Xingwen Lin; Baochang Gong; Qing Xiao (Remote Sensing of Environment, 2023)

Optimal design of horizontal axis tidal current turbine blade - Zhen-qi Li; Guang-nian Li; Lin Du; Hai-peng Guo; Wen-xin Yuan (Ocean Engineering, 2023)

Environmentally-friendly biorecovery of manganese from electrolytic manganese residue using a novel Penicillium oxalicum strain Z6-5-1: Kinetics and mechanism - Shuai Zhao; Bo-Wen Zheng; Yu-Cang Wang; Fei He; Li-Juan Wang; Xiong Lin; Xue-Mei Luo; Jia-Xun Feng (Journal of Hazardous Materials, 2023)

Roles of radical species in vacuum-UV/UV/peroxydisulfate advanced oxidation processes and contributions of the species to contaminant degradation at different water depths - Yu-Jia Nong; Yi-Lin Zhang; Uwe Hübner; Wen-Long Wang; Qian-Yuan Wu; Nan Huang; Jörg E. Drewes; Hong-Ying Hu (Journal of Hazardous Materials, 2023)

Simultaneous adsorption of As(III) and Pb(II) by the iron-sulfur codoped biochar composite: Competitive and synergistic effects - Yijun Chen; Qintie Lin; Xiaoqing Wen; Jin He; Haoyu Luo; Quanfa Zhong; Libin Wu; Jiaqi Li (Journal of Environmental Sciences, 2023)

Combustion mechanism and ash-to-gas products of star anise residues: Atmosphere and temperature dependencies and joint optimization - Tao Chen; Xiaoming Li; Jiayu Liang; Fatih Evrendilek; Xiaocui Wen; Sen Lin; Jingyong Liu (Fuel, 2023)

Characterization of procyanidin extracts from hawthorn (Crataegus pinnatifida) in human colorectal adenocarcinoma cell line Caco-2, simulated Digestion, and fermentation identified unique and novel prebiotic properties - Xue Han; Qian Zhou; Zhe Gao; Guanying Bianca Xu; Hong Chen; Bimal Chitrakar; Yasai Sun; Wen Zhao; Xuan Lin; Kaixuan Zhou; Zhisheng Zhang (Food Research International, 2023)

Polarity-extended composition profiling via LC-MS-based metabolomics approaches: A key to functional investigation of Citrus aurantium L - Wen Miao; Xiaojing Liu; Na Li; Xiqing Bian; Yiran Zhao; Jing He; Tingting Zhou; Jian-Lin Wu (Food Chemistry, 2023)

Discovery of novel ascorbic acid derivatives and other metabolites in fruit of Rosa roxburghii Tratt through untargeted metabolomics and feature-based molecular networking - Yaqi Zhang; Xiqing Bian; Guanyu Yan; Baoqing Sun; Wen Miao; Mingzheng Huang; Na Li; Jian-Lin Wu (Food Chemistry, 2023)

OSA-linear dextrin enhances the compactness of pea protein isolate nanoparticles: Increase of high internal phase emulsions stability - Xiao-Long Li; Wen-Jie Liu; Bao-Cai Xu; Bao Zhang; Wu Wang; Dong-Lin Su (Food Chemistry, 2023)

A highly sensitive electrochemical immunosensor based on electrospun nanocomposite for the detection of parathion - Wen-jia Yin; Jing-xian Zhang; Hong Wang; Yu Wang; Xi Zeng; Zhen-lin Xu; Jin-yi Yang; Zhi-li Xiao; Bruce D. Hammock; Peng Wen (Food Chemistry, 2023)

Comparison of tropomyosin released peptide and epitope mapping after in vitro digestion from fish (Larimichthys crocea), shrimp (Litopenaeus vannamei) and clam (Ruditapes philippinarum) through SWATH-MS based proteomics - LiLi Xu; Xiao Mei Zhang; Yun Qi Wen; Jin Long Zhao; Tong Cheng Xu; Ling Yong; Hong Lin; Hong Wei Zhang; Zhen Xing Li (Food Chemistry, 2023)

Storage stability of scallop (Patinopecten yessoensis) male gonad hydrolysates/κ-carrageenan composite hydrogels embeded curcumin - Jia-Nan Yan; Xin-Yu Jiang; Lin Li; Wen Sun; Bin Lai; Hai-Tao Wu (Food Hydrocolloids, 2023)

A novel l-rhamnose-binding lectin participates in defending against bacterial infection in zebrafish - Jing Wang; Xin-Lu Guo; Hong-Ye Chen; Lin-Xi Xiao; Gui-Wen Yang; Hui-Ting Yang (Fish & Shellfish Immunology, 2023)

Carnosic acid attenuated cytochrome c release through the mitochondrial structural protein Mic60 by PINK1 in SH-SY5Y cells - Chia-Yuan Lin; Yi-Chen Huang; Chi-Rei Wu; Han-Ting Wu; Ru-Huei Fu; Chia-Wen Tsai (Food and Chemical Toxicology, 2023)

Swallowtail butterflies and hawkmoths contribute equally to the pollination of Habenaria dentata (Orchidaceae) - Shao-Lin Tan; Xing-Hui Chen; Hai-Hong Liao; Lang Huang; Han-Wen Xiao; Huo-Lin Luo; Dong-Jin Xiong; Bo-Yun Yang; Zong-Xin Ren (Flora, 2023)

Quasi-zero-stiffness metamaterial pipe for low-frequency wave attenuation - Changqi Cai; Jiaxi Zhou; Kai Wang; Qida Lin; Daolin Xu; Guilin Wen (Engineering Structures, 2023)

Hepatoma-targeting and reactive oxygen species-responsive chitosan-based polymeric micelles for delivery of celastrol - Xue Zhang; Xueya Xu; Xiaoying Wang; Yajuan Lin; Yaling Zheng; Wen Xu; Jian Liu; Wei Xu (Carbohydrate Polymers, 2023)

Enhancement of water barrier and antimicrobial properties of chitosan/gelatin films by hydrophobic deep eutectic solvent - Haitao Wen; Daobang Tang; Yaosheng Lin; Jinhao Zou; Zhongyi Liu; Pengfei Zhou; Xuping Wang (Carbohydrate Polymers, 2023)

Corrigendum to “miR-7-5p overexpression suppresses cell proliferation and promotes apoptosis through inhibiting the ability of DNA damage repair of PARP-1 and BRCA1 in TK6 cells exposed to hydroquinone” [Chem. Biol. Interact. 283 (2018) 84–90] - Hao Luo; Hairong Liang; Yuting Chen; Shaoyun Chen; Yongchun Xu; Longmei Xu; Jiaxian Liu; Kairu Zhou; Jucheng Peng; Guoqiang Guo; Bei Lai; Li Song; et al. (Chemico-Biological Interactions, 2023)

Soil microbial community is resilient to thinning disturbance - Wan-Rou Lin; Wen-Cheng Chen; Pi-Han Wang (Tropical Ecology, 2023)

DOK7 Promotes NMJ Regeneration After Nerve Injury - Ethan D. Kosco; Hongyang Jing; Peng Chen; Wen-Cheng Xiong; Ivy S. Samuels; Lin Mei (Molecular Neurobiology, 2023)

TCR repertoire landscape reveals macrophage-mediated clone deletion in endotoxin tolerance - Juanjuan Zhao; Li Jia; YiJing Tao; Xu Zhao; Jing Yang; Yanxin Lu; Yaping Yan; Ling Mao; Lin Hu; Jia Lu; MengMeng Guo; Chao Chen; et al. (Inflammation Research, 2023)
Background Endotoxin tolerance (ET) is a protective mechanism in the process of sepsis, septic shock, and their sequelae including uncontrolled inflammation. Accumulating evidence has shown that peripheral T cells contribute to the induction of ET. However, what and how T-cell development contributes to ET inductions remain unclear. Methods Mice were intraperitoneally injected with LPS at a concentration of 5 mg/kg to establish an LPS tolerance model and were divided into two groups: a group examined 72 h after LPS injection (72-h group) and a group examined 8 days after LPS injection (8-day group). Injection of PBS was used as a control. We performed high-throughput sequencing to analyze the characteristics and changes of CD4 + SP TCR β CDR3 repertoires with respect to V direct to J rearrangement during the ET induction. Moreover, the proportion and proliferation, as well as surface molecules such as CD80 and CD86, of F4/80 + macrophages were analyzed using FCM. Furthermore, ACT assay was designed and administered by the tail vein into murine LPS-induced mouse model to evaluate the role of F4/80 + macrophages on the development of CD4 + SP thymocytes in ET condition. Results We found that the frequency and characteristics of the TCR β chain CDR3 changed obviously under condition of ET, indicating the occurrence of TCR rearrangement and thymocyte diversification. Moreover, the absolute numbers of F4/80 + macrophages, but not other APCs, were increased in thymic medulla at 72-h group, accompanied by the elevated function-related molecules of F4/80 + macrophages. Furthermore, adoptively transferred OVA 332-339 peptide-loaded macrophages into Rag-1 −/− mice induced the clone deletion of OVA-specific CD4 + SP, thereby ameliorating the pathology in lung tissue in LPS challenge. Conclusions These data reveal that the frequency and characteristics of the TCR β chain CDR3 undergo dynamic programming under conditions of LPS tolerance. Furthermore, the peripheral macrophages may be a key factor which carry peripheral antigen to thymic medulla and affect the negative selection of T-cell population, thereby contributing to the formation of ET. These results suggest that the clone selection in thymus in ET may confer protection against microbial sepsis.

Activity-density and spatial distribution of termites on a fine-scale in a tropical rainforest in Xishuangbanna, southwest China - Myo Thant; Xiaobing Lin; Anjana J. Atapattu; Min Cao; Shang-wen Xia; Shengjie Liu; Xiaodong Yang (Soil Ecology Letters, 2023)

Rapid shifts in thermal reaction norms and tolerance of brooded coral larvae following parental heat acclimation - Lei Jiang; Cheng‐Yue Liu; Guoxin Cui; Lin‐Tao Huang; Xiao‐Lei Yu; You‐Fang Sun; Hao‐Ya Tong; Guo‐Wei Zhou; Xiang‐Cheng Yuan; Yi‐Si Hu; Wen‐Liang Zhou; Manuel Aranda; et al. (Molecular Ecology, 2023)
Thermal priming of reef corals can enhance their heat tolerance; however, the legacy effects of heat stress during parental brooding on larval resilience remain understudied. This study investigated whether preconditioning adult coral Pocillopora damicornis to high temperatures (29°C and 32°C) could better prepare their larvae for heat stress. Results showed that heat‐acclimated adults brooded larvae with reduced symbiont density and shifted thermal performance curves. Reciprocal transplant experiments demonstrated higher bleaching resistance and better photosynthetic and autotrophic performance in heat‐exposed larvae from acclimated adults compared to unacclimated adults. RNA‐seq revealed strong cellular stress responses in larvae from heat‐acclimated adults that could have been effective in rescuing host cells from stress, as evidenced by the widespread upregulation of genes involved in cell cycle and mitosis. For symbionts, a molecular coordination between light harvesting, photoprotection and carbon fixation was detected in larvae from heat‐acclimated adults, which may help optimize photosynthetic activity and yield under high temperature. Furthermore, heat acclimation led to opposing regulations of symbiont catabolic and anabolic pathways and favoured nutrient translocation to the host and thus a functional symbiosis. Notwithstanding, the improved heat tolerance was paralleled by reduced light‐enhanced dark respiration, indicating metabolic depression for energy saving. Our findings suggest that adult heat acclimation can rapidly shift thermal tolerance of brooded coral larvae and provide integrated physiological and molecular evidence for this adaptive plasticity, which could increase climate resilience. However, the metabolic depression may be maladaptive for long‐term organismal performance, highlighting the importance of curbing carbon emissions to better protect corals.

Coral reef resilience persisted for a millennium but has declined rapidly in recent decades - Ting Zhang; Tianran Chen; Sheng Liu; Xianzhi Lin; Shu Li; Wen Yan (Frontiers in Marine Science, 2023)
The lack of long-term records of coral community composition restricts our understanding of the contemporary ecological states of tropical reefs. Here we integrated paleo-ecological reconstruction, historical mortality evidence, and ecological survey data to determine the temporal variability in reef resilience of the Nansha atolls in the tropical western Pacific. Subfossil coral assemblages extracted from the reef cores exhibited no evidence of community shifts attributable to centennial-scale changes in El Niño variability during the last millennium, suggesting long-term stability in community structure and persistence of reef resilience. By contrast, ecological surveys revealed a major collapse in the reef ecosystem, and high-precision U-series dating of dead Acropora fragments indicated that this collapse occurred in recent decades and was especially relevant to several strong/extreme El Niño episodes. Frequent and intensive El Niño−Southern Oscillation and marine heatwaves have overwhelmed the reefs’ resistive and recovery capacity, thereby impairing reef resilience.

Genome-wide association study reveals markers and candidate genes associated with growth in the rice flower carp, an economic fish species of integrated rice-fish culture in China - Hui Luo; Xianhui Pan; Yin Huang; Zhe Li; Hua Ye; Kangqi Zhou; Luting Wen; Junqi Qin; Wenping He; Xuesong Du; Dapeng Wang; Yong Lin (Frontiers in Marine Science, 2023)
The rice flower carp ( Cyprinus carpio ) is an important fish in integrated rice-fishery farming. Here, we performed the first genome-wide association study (GWAS) for seven growth traits (including body mass, total length, body length, body height, body width, caudal-peduncle depth, and eye spacing) in 200 rice flower carp samples using 369,688 high-quality SNPs and 42,225 indels obtained by double-digest genotyping-by-sequencing (ddGBS). The morphometrics of these traits were highly correlated (Pearson’s correlation coefficients = 0.74–0.99, p < 0.001). GWAS detected 15, 5, 4, 26, 7, 16, and 17 loci significant associated (-log10P ≥ 5) with body mass, total length, body length, body width, body height, caudal-peduncle depth, and eye spacing, respectively. Subsequently, within the 50 kb upstream and downstream regions surrounding these significant loci, 38, 19, 18, 20, 52, 27, and 37 candidate genes for the seven growth traits were detected, respectively. Importantly, B6_4352672 and A8_4978825 were significantly associated with more than five growth traits. These results showed loci significantly associated with more than five growth traits will be helpful for future marker-assisted selection (MAS). Interestingly, chromosomes A8 and B25 had many loci significantly associated with growth traits, most of which were shared among multiple growth-related traits. These results indicated that chromosome A8 and B25 may be closely related to growth traits. Our findings not only help understand the genetic architecture of growth traits in fish but facilitate the identification of candidate genes for marker-assisted selection towards breeding faster-growing rice flower carp in the future.

Towards effective wildlife protection law for marine species in China: A stakeholders’ perspective - Kit Yue Kwan; Ruifang Chen; Chun-Chieh Wang; Shuhao Lin; Lv Wu; Xiaoyong Xie; Zhaohong Weng; Menghong Hu; Haichao Zhou; Zhou Wu; Yijian Fu; Wenquan Zhen; et al. (Frontiers in Marine Science, 2023)
Introduction As one of the megadiverse countries, the effectiveness of wildlife protection in China is of great significance to global biodiversity conservation. With continued evolution and revisions, China’s Wildlife Protection Law has listed over 140 marine species; however, it is still inclined toward terrestrial animals. Methods To narrow the gap between compliance and enforcement, we collected 1,309 effective responses from various coastal cities of China through an anonymous online questionnaire survey, to investigate their exposure, understanding and attitudes toward Wildlife Protection Law for marine species (mWPL). Results Most respondents demonstrated an overall good understanding about the context, necessity and effectiveness of mWPL. The fisher communities were found to be more aware of the dissemination and implementation of mWPL. However, they understood less of the penal system, and exhibited negative attitudes toward the necessity and punishment of the legislation, probably due to the conflicts between resource utilizations and legislative interventions. The participants also indicated that seahorses, horseshoe crabs and corals were commonly subjected to illegal exploitations. Discussion While most respondents suggested greater fines, tighter laws and better public enforcement, we advocate the exploration of bottom-up options such as community engagement and environmental education to improve compliance and implementation of mWPL for the benefit of marine wildlife conservation in China.

Establishing the Safe Space via Physiologically Based Biopharmaceutics Modeling. Case Study: Fevipiprant/QAW039 - Alexandros Kourentas; Monika Gajewska; Wen Lin; Sundeep S. Dhareshwar; Caroline Steib-Lauer; Swarupa Kulkarni; Stefan Hirsch; Tycho Heimbach; Martin Mueller-Zsigmondy (The AAPS Journal, 2023)

Laboratory simulated aging methods, mechanisms and characteristic changes of microplastics: A review - Lin Wang; Jianqiang Zhang; Wen Huang; Yang He (Chemosphere, 2023)

Establishing a high-performance anti-fouling PEI-ZIF-PAA membrane with improved Lewis acid-base interactions and hydrophilicity - Zhang-Hong Wan; Jing Guan; Chun-Miao Zhang; Wen-Qing Fei; Lin Wang; Shu-Guang Wang; Xue-Fei Sun (Chemosphere, 2023)

Biotransformation of sulfamonomethoxine in a granular sludge system: Pathways and mechanisms - Meng-Yuan Li; Run-Dong Zhang; Yi-Xing Lin; Qi-Wen Li; Qiu-Yue Zhao; Zong-Xi Zhao; Zhong-Ming Ling; Long-Fei Shu; Min Zhang; Li-Xin Hu; Yi-Jing Shi; Guang-Guo Ying (Chemosphere, 2023)

Enhancing mechanical and photocatalytic properties by surface microstructure regulation of TiO2 nanofiber membranes - Xilin Liao; Hai-Tao Ren; Baolei Shen; Jia-Horng Lin; Ching-Wen Lou; Ting-Ting Li (Chemosphere, 2023)

The extract from aerial part of Scutellaria baicalensis regulates gut microbiota in rabbit fish: Replacement of antibiotic fighting against pathogenic bacteria - Yi-Teng Xia; Edwin Hok-Chi Cheng; Huai-You Wang; Lynn Hoi-Lam Zhang; Sheng-Ying Lin; Tina Ting-Xia Dong; Ran Duan; Qi-Wei Qin; Wen-Xiong Wang; Karl Wah-Keung Tsim (Aquaculture, 2023)

Meta-analysis of studies on protection provided by different prophylactic agents, their routes of administration and incubation times against nodavirus infection in Macrobrachium rosenbergii - Ken Fong Chen; Sathiya Maran; Wen Siang Tan; Lin Kooi Ong; Syafiq Asnawi Zainal Abidin; Iekhsan Othman; Beng Ti Tey; Ronald Fook Seng Lee (Aquaculture, 2023)

Differences in lipid accumulation and mobilization in the hepatopancreas and ovary of female mud crab (Scylla paramamosain, Estampador, 1949) during ovarian development - Baojia Chen; Jia Zheng; Cuiying Chen; Kun Wu; Fan Lin; Lijun Ning; Hua Rong; Chuan Chen; Fei Xiao; Haotian Zhang; Xiaobo Wen (Aquaculture, 2023)

Water quality criteria derivation and tiered ecological risk evaluation of antifouling biocides in marine environment - Hai-Wei Luo; Min Lin; Xin-Xin Bai; Bin Xu; Minjie Li; Jin-Jian Ding; Wen-Jun Hong; Liang-Hong Guo (Marine Pollution Bulletin, 2023)

Food values drive Chinese consumers' demand for meat and milk substitutes - Jiayu Sun; David L. Ortega; Wen Lin (Appetite, 2023)

Ecological value of mariculture shellfish resources in China: Assessment and management - Chun-Yu Lin; Gui-Lin Dai; Yang Liu; Meng-Qi Zhang; Ying Liu; Wen Jiang; Xiu-Mei Fu; Han-Xue Chen (Marine Policy, 2023)

Pre-exposure of peracetic acid enhances its subsequent combination with ultraviolet for the inactivation of fungal spores: Efficiency, mechanisms, and implications - Wei Lin; Jie Zuo; Kai Li; Ruizhu Hu; Xiangqian Xu; Tinglin Huang; Gang Wen; Jun Ma (Water Research, 2023)

Kidney Mesenchymal stem cells alleviate cisplatin-induced kidney injury and apoptosis in rats - Rui-ning Liang; De-qi Yan; Xing-ping Zhang; Xu Chen; Wen-hui Zhang; Hong-lin Jia (Tissue and Cell, 2023)

Chlorpyrifos induces neuronal cell death via both oxidative stress and Akt activation downstream-regulated CHOP-triggered apoptotic pathways - Jhe-Wei Lin; Shih-Chang Fu; Jui-Ming Liu; Shing-Hwa Liu; Kuan-I Lee; Kai-Min Fang; Ren-Jun Hsu; Chun-Fa Huang; Kun-Min Liu; Kai-Chih Chang; Chin-Chuan Su; Ya-Wen Chen (Toxicology in Vitro, 2023)

Ambient relative humidity-dependent obstructive sleep apnea severity in cold season: A case-control study - Kuan-Jen Bai; Wen-Te Liu; Yuan-Chien Lin; Yansu He; Yueh-Lun Lee; Dean Wu; Ta-Yuan Chang; Li-Te Chang; Chun-Yeh Lai; Cheng-Yu Tsai; Kian Fan Chung; Kin-Fai Ho; et al. (Science of The Total Environment, 2023)

Ecological risk assessment and corrective actions for dioxin-polluted sediment in a chemical plant's brine water storage pond - Chi-Wei Huang; Wen-Yen Huang; Chitsan Lin; Yi-Lin Li; Tsung-Po Huang; Xuan-Thanh Bui; Huu Hao Ngo (Science of The Total Environment, 2023)

Spatial allocation of LID practices with a water footprint approach - Wen-Kai Chuang; Zih-Ee Lin; Tzu-Chi Lin; Shang-Lien Lo; Chia-Lin Chang; Pei-Te Chiueh (Science of The Total Environment, 2023)

ARSCP: An antimicrobial residue surveillance cloud platform for animal-derived foods - Jun-Jun Yu; Ya-Lin Hu; Cheng-Zheng Liu; Shuai-Bin Wu; Zi-Jian Zheng; Ze-Hua Cui; Li Chen; Tian Wei; Shi-Kai Sun; Jun Ning; Xiang Wen; Qiu-Yue Diao; et al. (Science of The Total Environment, 2023)

Enhanced sulfolane-contaminated groundwater degradation and power generation by a mini tubular microbial fuel cell/electro-Fenton combined system - Shu-Hui Liu; Yen-Ni Tsai; Chiaying Chen; Chi-Wen Lin; Ting-Jun Zhu (Process Safety and Environmental Protection, 2023)

A numerical investigation of the transport process of density currents over steep slopes and its implications for subsea cable breaks - Sheng-De Tsai; Jia-Lin Chen; Wen-Yang Hsu; Wei-Zhan Tsai; Andhy Romdani (Ocean Engineering, 2023)

Typhoon-induced suspended sediment dynamics in the mouth-bar region of a river/wave-dominated estuary - Mingen Liang; Jing Liu; Yitong Lin; Zixiao He; Wen Wei; Liangwen Jia (Marine Geology, 2023)

Transcriptomic data recover a new superfamily-level phylogeny of Cucujiformia (Coleoptera, Polyphaga) - Ming-Long Yuan; Wen-Ting Chen; Qi-Lin Zhang; Min Li; Li Zhang; Pei-An Tang (Molecular Phylogenetics and Evolution, 2023)

Promoting removal of copper from sediment and production of bioelectricity by sediment microbial fuel cells using tea extracts - Shu-Hui Liu; Chu-Yuan Yang; Chi-Wen Lin; Ting-Jun Zhu (Journal of Water Process Engineering, 2023)

Sonocatalytic removal of tetracycline in the presence of S-scheme Cu2O/BiFeO3 heterojunction: Operating parameters, mechanisms, degradation pathways and toxicological evaluation - Xin Wang; Xue-Song He; Chun-Yu Li; Shi-Lin Liu; Wen Lu; Zheng Xiang; Yang Wang (Journal of Water Process Engineering, 2023)

Characterization of fibroblast growth factor receptor 4 (FGFR4) from the red swamp crayfish Procambarus clarkii and its role in antiviral and antimicrobial immune responses - Yan-Mei Zhang; Chen-Yang Lin; Bang-Ze Li; Wen-Bin Xu; Wei-Ren Dong; Miao-An Shu (Journal of Invertebrate Pathology, 2023)

Immobilizing copper in loess soil using microbial-induced carbonate precipitation: Insights from test tube experiments and one-dimensional soil columns - Yi-Xin Xie; Wen-Chieh Cheng; Lin Wang; Zhong-Fei Xue; Md Mizanur Rahman; Wenle Hu (Journal of Hazardous Materials, 2023)

Photothermal and Concus Finn capillary assisted superhydrophobic fibrous network enabling instant viscous oil transport for crude oil cleanup - Ting Dong; Yanhui Liu; Na Tian; Yuanming Zhang; Guangting Han; Fudi Peng; Ching-Wen Lou; Shan Chi; Yanming Liu; Cui Liu; Jia-Horng Lin (Journal of Hazardous Materials, 2023)

Exploring the abundance and influencing factors of antimicrobial resistance genes in manure plasmidome from swine farms - Zunfang Tu; Junrui Shui; Jinxin Liu; Hongmei Tuo; Haoyu Zhang; Cong Lin; Jingyi Feng; Yuxuan Feng; Wen Su; Anyun Zhang (Journal of Environmental Sciences, 2023)

Gastrodin ameliorates exercise-induced fatigue via modulating Nrf2 pathway and inhibiting inflammation in mice - Yaping Zhou; Qi Wu; Wen Yu; Fan Ye; Yunyun Cao; Otobong D. Akan; Xiuxiu Wu; Tiantian Xie; Han Lu; Fuliang Cao; Feijun Luo; Qinlu Lin (Food Bioscience, 2023)

Joint effects of per- and polyfluoroalkyl substance alternatives and heavy metals on renal health: A community-based population study in China - Li-Xia Liang; Pengxin Dong; Yang Zhou; Lin Zhang; Zhengmin Qian; Sarah Dee Geiger; Elizabeth Bingheim; Xiaojiang Tang; Yan Wu; Jiayun Lv; Li-Zi Lin; Mohammed Zeeshan; et al. (Environmental Research, 2023)

Immobilizing of lead and copper using chitosan-assisted enzyme-induced carbonate precipitation - Lin Wang; Wen-Chieh Cheng; Zhong-Fei Xue; Bin Zhang; Xin-Jiang Lv (Environmental Pollution, 2023)

Associations between maternal phthalate exposure and neonatal neurobehaviors: The Taiwan maternal and infant cohort study (TMICS) - Hsing-Kang Chen; Shu-Li Wang; Yu-Hsun Chang; Chien-Wen Sun; Ming-Tsang Wu; Mei-Lien Chen; Yu-Jie Lin; Chia-Jung Hsieh (Environmental Pollution, 2023)

Lactoferrin attenuated urban particulate matter-induced nephrotoxicity by regulating the CSF2/CENPE axis - Wen-Chih Liu; Hui-Wen Chiu; Chu-Lin Chou; Yu-Jhe Chiu; Yu-Hsuan Lee (Environmental Pollution, 2023)

Acute exposure to microcystins affects hypothalamic-pituitary axes of male rats - Ting Shi; Lin-Lin Xu; Liang Chen; Jun He; Ye-Ke Wang; Feng Chen; Yang Chen; John P. Giesy; Yu-Ting Wang; Qian-Hui Wu; Wen-Li Xu; Jun Chen; et al. (Environmental Pollution, 2023)

Origin of clay in granite intrusive contact zone and its influence on tunnel deformation and instability - Guo-Hua Zhang; Bo-Wen Zhang; Fei Tan; Zhong-Hou Liu; Jun-Peng Zou; Zhong-Zhi Xie; Jin-Quan Wu; Zhi-Ping Lin; Zhan-Rong Zhang (Engineering Geology, 2023)

Highly efficient shrimp shell recovery by solid-state fermentation with Streptomyces sp. SCUT-3 - De-Lin Lu; Ming-Shu Zhang; Jun-Jin Deng; Wen-Jun Lu; Zhen-Dong Yang; Zhi-Wei Li; Yu-Chen Chen; Xiao-Chun Luo (Chemical Engineering Journal, 2023)

Targeted therapy for autoimmune diseases based on multifunctional frame nucleic acid system: Blocking TNF-α-NF-κB signaling and mediating macrophage polarization - Mei Zhang; Yuting Wen; Zhangheng Huang; Xin Qin; Mi Zhou; Dexuan Xiao; Weitong Cui; Zhiqiang Liu; Yunfeng Lin (Chemical Engineering Journal, 2023)

MOF-templated hollow cobalt sulfide as an enhanced Oxone activator for degradation of UV Absorber: Key role of sulfur Vacancy-Induced highly active CoII sites - Ta Cong Khiem; Xiaoguang Duan; Wei-Jie Liu; Young-Kwon Park; Ha Manh Bui; Wen-Da Oh; Suresh Ghotekar; Yiu Fai Tsang; Kun-Yi Andrew Lin (Chemical Engineering Journal, 2023)

Clay nanosheets simultaneously intercalated and stabilized by PEGylated chitosan as drug delivery vehicles for cancer chemotherapy - Hsuan-Jung Huang; Shih-Yu Huang; Tzu-Hao Wang; Tzu-Yun Lin; Nan-Ching Huang; Orion Shih; U-Ser Jeng; Che-Yi Chu; Wen-Hsuan Chiang (Carbohydrate Polymers, 2023)

Research on type I kerogen molecular simulation and docking between kerogen and saturated hydrocarbon molecule during oil generation - Tian Liang; Zhao-Wen Zhan; Yan-Rong Zou; Xiao-Hui Lin; Yun Shan; Ping'’an Peng (Chemical Geology, 2023)

Bixasteroid, a new compound from the fruits of Bixa orellana and its anti-inflammatory activity - Yi-min Chen; Tian-qi Xu; Xiao-qi Zhang; Chun-lin Fan; Wen-cai Ye; Wei Xu; Guang-xiong Zhou (Natural Product Research, 2023)

Solvent-Based Soil Washing of Mercury-Contaminated Soil with Eco-friendly Washing Agents - Wazir Aitizaz Ahsan; Hong-Giang Hoang; Qiong-Jia Zhang; Chitsan Lin; Wen-Yen Huang; Minh Ky Nguyen; Adnan Hussain (Water, Air, & Soil Pollution, 2023)

Structure, Intracellular Localisation and Expression Analysis of Sucrose Nonfermenting-Related Kinase ShSnRK1α in Sugarcane - Ting-ting Zhao; Jun-gang Wang; Wen-zhi Wang; Cui-lian Feng; Xiao-yan Feng; Lin-bo Shen; Shu-zhen Zhang (Sugar Tech, 2023)

Establishment of an efficient method for kiwifruit in vitro micrografting - Wantian Yao; Lingling Kong; Diya Lei; Bing Zhao; Honglan Tang; Xuan Zhou; Yuanxiu Lin; Yunting Zhang; Yan Wang; Wen He; Mengyao Li; Qing Chen; et al. (Plant Cell, Tissue and Organ Culture (PCTOC), 2023)

The detection of major clades and new species of Mallocybe (Inocybaceae, Agaricales) from China with elongate cheilocystidia - Jian-Hua Hu; Wen-Jie Yu; Lun-Sha Deng; Yu-Guang Fan; Tolgor Bau; Li-Ping Tang; Wen-Fei Lin; Chun-Ying Deng (Mycological Progress, 2023)

Expression of Concern: Folic acid rivals methylenetetrahydrofolate reductase (MTHFR) gene-silencing effect on MEPM cell proliferation and apoptosis - Wen-lin Xiao; Min Wu; Bing Shi (Molecular and Cellular Biochemistry, 2023)

Analyzing landslide-induced debris flow and flow-bridge interaction by using a hybrid model of depth-averaged model and discrete element method - Wen-Jie Shiu; Ching-Fang Lee; Chia-Chi Chiu; Meng-Chia Weng; Che-Ming Yang; Wei-An Chao; Chun-Yuan Liu; Cheng-Han Lin; Wei-Kai Huang (Landslides, 2023)

Phosphorus availability mediates plant–plant interaction and field productivity in maize-grass pea intercropping system: Field experiment and its global validation - Shuang-Guo Zhu; Hong-Yan Tao; Wen-Bo Li; Rui Zhou; Yan-Wen Gui; Li Zhu; Xiao-Lin Zhang; Wei Wang; Bao-Zhong Wang; Fu-Jian Mei; Hao Zhu; You-Cai Xiong (Agricultural Systems, 2023)

Antiherbivore effect of Cuscuta campestris against Spodoptera frugiperda - Chang-Lin Sung; Fang-Yu Hu; Yi Li; Shin-Fu Tsai; Wen-Po Chuang (Arthropod-Plant Interactions, 2023)

Mechanism of oceanic eddies in modulating the sea surface temperature response to a strong typhoon in the western North Pacific - Sheng Lin; Wen-Zhou Zhang; Yuntao Wang; Fei Chai (Frontiers in Marine Science, 2023)
Eddies are ubiquitous mesoscale dynamics in oceans worldwide that prominently influence the upper ocean. Specifically, the presence of preexisting eddies can modulate oceanic responses to passing typhoons, for which the underlying mechanism requires further investigation. In 2013, Typhoon Soulik traveled over 2,000 km in the western North Pacific, encountering multiple eddies, offering a suitable opportunity for investigating the impact of eddies on typhoon-induced upper ocean responses. A coupled ocean-atmosphere model was developed for this event, and the simulations were validated with multiple observations. The surface cold wake after Typhoon Soulik was successfully reproduced by the coupled model, showing a multicore structure, which was due to the preexisting mesoscale cyclonic eddies along the typhoon path. An experimental case excluding eddies was also tested in the numerical model. The comparison between the control and experimental cases revealed that sea surface cooling was enhanced by eddies via the vertical mixing and horizontal advection of eddy-related currents. In particular, vertical mixing enhanced sea surface cooling beneath the typhoon center due to the stronger vertical stratification within the preexisting cyclonic oceanic eddies. The eddy-related current with a horizontal temperature gradient contributed to advection, enhancing sea surface cooling at the cooling center and leading to a rightward-shifted pattern of enhanced sea surface cooling. This study enriches the understanding of the complex upper ocean dynamics under the combined effects of typhoons and eddies.

Halorarius litoreus gen. nov., sp. nov., Halorarius halobius sp. nov., Haloglomus halophilum sp. nov., Haloglomus salinum sp. nov., and Natronomonas marina sp. nov., extremely halophilic archaea isolated from tidal flat and marine solar salt - Ya-Ping Sun; Bei-Bei Wang; Zhang-Ping Wu; Xi-Wen Zheng; Jing Hou; Heng-Lin Cui (Frontiers in Marine Science, 2023)
Five novel halophilic archaeal strains, named BND22 T , ZY10 T , ZY41 T , ZY58 T , and ZY43 T , were isolated from the coastal saline sediment of the intertidal zone located in Qingdao and the natural sea salt produced from Huanghua marine solar saltern, PRChina. These five strains demonstrated the typical morphology and growth characteristics of haloarchaea. The comparison of 16S rRNA gene revealed that strain BDN22 T was associated with Salinirubellus salinus ZS-35-S2 T (95.2% similarity), strain ZY10 T was related to Halosegnis rubeus F17-44 T (95.1% similarity), both strains ZY41 T and ZY58 T were closely related to Haloglomus irregulare F16-60 T (98.1% and 98.2% similarities, respectively), and strain ZY43 T was close to Natronomonas salina YPL13 T (98.0% similarity). In addition to the 16S rRNA gene, the rpoB′ gene is undoubtedly another important molecular marker for the identification of halophilic archaea, and concatenated-conserved-protein phylogeny was widely used in archaeal classification in recent years. Phylogenetic and phylogenomic analyses based on rpoB′ genes and 122 concatenated archaeal protein genes showed that these haloarchaea construct three different clades and gathered together with the current members of Haloarculaceae . Strains BND22 T and ZY10 T formed two distinct clades separated from Salinirubellus salinus ZS-35-S2 T and Halosegnis members, strains ZY41 T and ZY58 T clustered with Haloglomus irregulare F16-60 T , and strain ZY43 T gathered with the current members of Natronomonas. The ANI, DDH, and AAI values of these five strains against phylogenetic neighbours were no more than 91%, 45%, and 92%, respectively, far below the cut-off values for species delineation, supporting their placements in new taxa. Based on the phenotypic, chemotaxonomic, phylogenetic, and phylogenomic properties, these five strains represent five novel taxa of the family Haloarculaceae , Halorarius litoreus gen. nov., sp. nov. (type strain BND22 T = CGMCC 1.18780 T = JCM 34966 T ), Halorarius halobius sp. nov. (type strain ZY10 T = CGMCC 1.17475 T = JCM 34319 T ), Haloglomus halophilum sp. nov. (type strain ZY41 T = CGMCC 1.17030 T = JCM 34161 T ), Haloglomus salinum sp. nov. (type strain ZY58 T = CGMCC 1.17216 T = JCM 34163 T ), and Natronomonas marina sp. nov. (type strain ZY43 T = CGMCC 1.17202 T = JCM 34162 T ). This is the first report of description of a novel haloarchaeon isolated from a marine intertidal zone.

Seismic Multiple Attenuation in the Continent–Ocean Transition Zone of the Northern South China Sea - Nan Chen; Chun-Feng Li; Yong-Lin Wen; Peng Wang; Xiu-Lian Zhao; Xiao-Li Wan (Journal of Marine Science and Engineering, 2023)
In this study, we process four new multichannel reflection seismic profiles acquired in 2015 and 2016 in the continent–ocean transition zone (COT) of the northern South China Sea (SCS). We apply a multi-domain, progressive, and seabed-controlled denoising technique and obtain a good denoising effect. Combining velocity analysis in the multi-round time domain and forward modeling, we analyze the types and characteristics of multiples in the study area and formulate an effective demultiple technique to attenuate strong seabed multiples, diffracted multiples from rough seafloor, and other multiples from deep reflectors. The processing results show that the sea surface-related multiple elimination technique predicts the sea surface-related multiples accurately by data convolution, and has a good effect in attenuating seabed multiples. Diffracted multiple attenuation method extracts high-frequency and high-energy diffracted multiples, and suppresses multiples by the energy ratios of multiples to primary events. To attenuate deep multiples, we select predictive deconvolution to attenuate periodic deep multiples after many trials and detailed analysis. The combination of these different techniques in sequence proves to be quite effective in attenuating different seismic multiples in the COT. The imaged crustal structures near the COT often show strong magmatism and/or basement uplifting. The faulted and thinned continental crust adjacent to the COT corresponds to the lowest free-air gravity anomalies. Gravity anomalies often increase from the COT to the oceanic crust. An exception is to the northeast of the SCS, where the relatively wide COT shows very high gravity anomalies, likely induced by mantle upwelling and serpentinization.

The construction of high efficient visible-light-driven 3D porous g-C3N4/Fe3O4 photocatalyst: A new photo-induced bacterial inactivation material enhanced by cascade photo-Fenton reaction - Ze-Yu Liu; Wen-Qian Huang; Chuan-Qing Huang; Zhao-Zhen Liu; Xiao-Yue Tang; Wei-Chang Chen; Zheng-Zheng Tang; Yu-Xing Huang; Shuo-Chun Zheng; Lin Lin; Changzhu Li; Yong Ye (Chemosphere, 2023)

Revealing microcystin-LR ecotoxicity to earthworm (Eisenia fetida) at the intestinal cell level - Xiang Liu; Jin-Cheng Ye; Fen Li; Rong-Jun Gao; Xiao-Xiao Wang; Ji-Liang Cheng; Bai-Lin Liu; Lei Xiang; Yan-Wen Li; Quan-Ying Cai; Hai-Ming Zhao; Ce-Hui Mo; et al. (Chemosphere, 2023)

Effective multipurpose sewage sludge and food waste reduction strategies: A focus on recent advances and future perspectives - Xuefeng Zhu; Yuting Xu; Guangyin Zhen; Xueqin Lu; Suyun Xu; Jie Zhang; Lin Gu; Haifeng Wen; Hongbo Liu; Xuedong Zhang; Zhichao Wu (Chemosphere, 2023)

VUV/UV oxidation performance for the elimination of recalcitrant aldehydes in water and its variation along the light-path - Wan-Yue Ouyang; Wen-Long Wang; Yi-Lin Zhang; Han-Ying Cai; Qian-Yuan Wu (Water Research, 2023)

Modelling the Public Perception of Urban Public Space Lighting Based on SDGSAT-1 Glimmer Imagery: A Case Study in Beijing, China - Zirong Lin; Weili Jiao; Huichan Liu; Tengfei Long; Yongkun Liu; Shengrong Wei; Guojin He; Boris A. Portnov; Tamar Trop; Ming Liu; Xuwen Li; Chunhui Wen (Sustainable Cities and Society, 2023)

Composition of dissolved organic matter (DOM) in wastewater treatment plants influent affects the efficiency of carbon and nitrogen removal - Ling Wen; Fang Yang; Xuan Li; Siwan Liu; Yuye Lin; En Hu; Li Gao; Ming Li (Science of The Total Environment, 2023)

Mapping Chinese annual gross primary productivity with eddy covariance measurements and machine learning - Xian-Jin Zhu; Gui-Rui Yu; Zhi Chen; Wei-Kang Zhang; Lang Han; Qiu-Feng Wang; Shi-Ping Chen; Shao-Min Liu; Hui-Min Wang; Jun-Hua Yan; Jun-Lei Tan; Fa-Wei Zhang; et al. (Science of The Total Environment, 2023)

Sources, transport, and visibility impact of ambient submicrometer particle number size distributions in an urban area of central Taiwan - Li-Hao Young; Chih-Sheng Hsu; Ta-Chih Hsiao; Neng-Huei Lin; Si-Chee Tsay; Tang-Huang Lin; Wen-Yinn Lin; Chau-Ren Jung (Science of The Total Environment, 2023)

Zero-valent iron boosts nitrate-to-ammonia bioconversion via extracellular electron donation and reduction pathway complementation - Xue Li; Jie Li; Xiao-Rong Yu; Yong-Kun Zhu; Hou-Qi Liu; Lin Chen; Jing Wu; Xian-Zhong Fu; Shuo Cui; Tian-Yin Huang; Ru-Quan Ye; Wen-Wei Li (Resources, Conservation and Recycling, 2023)

Widely targeted metabolomics analysis reveals the effect of exogenous auxin on postharvest resistance to Botrytis cinerea in kiwifruit (Actinidia chinensis L.) - Zhe-Xin Li; Shuai Yang; Xu Wang; Qin-Hong Liao; Wen-Lin Zhang; Jing Liu; Guo-Hua Liu; Jian-Min Tang (Postharvest Biology and Technology, 2023)

Experimental study on the distribution law of the blade foot resistance of a large deep-water open caisson in sand - Bing-nan Jiang; Ting Yu; Wen-ming Peng; Ying-bin Zhang; Shun-bin He; Jian-lin Ma (Ocean Engineering, 2023)

Wild coral oocytes are more amenable to low temperature preservation than cultured counterparts - Chiahsin Lin; Cheng-Chia Lin; Fu-Wen Kuo; Sujune Tsai (Marine Environmental Research, 2023)

Constructing self-assembled microtubular structured Zn–In–S and modulation mechanism towards efficient photocatalytic degradation of tetracycline - Xiaoman Li; Xiaolan Guo; Jiliang Niu; Jialiang Lin; Jianhua Cheng; Yongyou Hu; Yuancai Chen; Weiqiu Wen (Journal of Cleaner Production, 2023)

Impacts of hydraulic conditions on microplastics biofilm development, shear stresses distribution, and microbial community structures in drinking water distribution pipes - Xiao Chen; Xiao-ying Lian; Yi Wang; Sheng Chen; Yi-ran Sun; Guo-lin Tao; Qiao-wen Tan; Jing-chun Feng (Journal of Environmental Management, 2023)

Target anisotropic scattering deduction model using multi-aspect SAR data - Xiaoyang Yue; Fei Teng; Yun Lin; Wen Hong (ISPRS Journal of Photogrammetry and Remote Sensing, 2023)

The largest rock avalanche in China at Iymek, Eastern Pamir, and its spectacular emplacement landscape - An-Wen Shi; Yu-Feng Wang; Qian-Gong Cheng; Qi-Wen Lin; Tian-Hua Li; Bernd Wünnemann (Geomorphology, 2023)

Capital endowment, health information literacy and healthy dietary behaviors: Evidence from a survey of Chinese rural residents - Yiqin Wang; Xiaowei Wen; Wenwen Liang; Xiaoxi Lin (Food Quality and Preference, 2023)

Diet-rich in wheat bran modulates tryptophan metabolism and AhR/IL-22 signalling mediated metabolic health and gut dysbacteriosis: A novel prebiotic-like activity of wheat bran - Tao Yan; Lin Shi; Tianqi Liu; Xiangnan Zhang; Minmin Yang; Wen Peng; Xiaomin Sun; Lijing Yan; Xiaoshuang Dai; Xinbing Yang (Food Research International, 2023)

The associations of particulate matter short-term exposure and serum lipids are modified by vitamin D status: A panel study of young healthy adults - Jia-Min Li; Han-Yu Yang; Si-Han Wu; Shyamali C. Dharmage; Bin Jalaludin; Luke D. Knibbs; Michael S. Bloom; Yuming Guo; Lidia Morawska; Joachim Heinrich; Yim Steve Hung Lam; Li-Zi Lin; et al. (Environmental Pollution, 2023)

Association between long-term ambient ozone exposure and attention-deficit/hyperactivity disorder symptoms among Chinese children - Peien Zhou; Wangjian Zhang; Yu-Jie Xu; Ru-Qing Liu; Zhengmin Qian; Stephen Edward McMillin; Elizabeth Bingheim; Li-Zi Lin; Xiao-Wen Zeng; Bo-Yi Yang; Li-Wen Hu; Wen Chen; et al. (Environmental Research, 2023)

Using cluster algorithms with a machine learning technique and PMF models to quantify local-specific origins of PM2.5 and associated metals in Taiwan - Chin-Yu Hsu; Jhy-Charm Soo; Sheng-Lun Lin; Chih-Da Wu; Kai Hsien Chi; Wen-Chang Hsu; Chun-Chieh Tseng; Yu-Cheng Chen (Environmental Pollution, 2023)

Identification of serum metabolic signatures of environmental-leveled phthalate in the Taiwanese child population using NMR-based metabolomics - Sheng-Han Lee; Zhi-Yi Du; Wei-Chen Tseng; Wan-Yu Lin; Mei-Huei Chen; Ching-Chun Lin; Hao-Jan Liang; Hui-Ju Wen; Yue-Leon Guo; Pau-Chung Chen; Ching-Yu Lin (Environmental Pollution, 2023)

Cation-doped V2O5 microsphere as a bidirectional catalyst to activate sulfur redox reactions for lithium-sulfur batteries - Fan-Jun Liu; Wen-Lin Luo; Ze Zhang; Ji Yu; Jian-Xin Cai; Zhen-Yu Yang (Chemical Engineering Journal, 2023)

Developing membrane reactors with suspended polyphthalocyanine nanoplatelets for upscaling syntheses of protein-polymer bioconjugates - Wen Fang Wei; Wan Lin Guo; Min Jian; Liu Shu Qin; Xue Li; Tao Cai (Chemical Engineering Journal, 2023)

Realizing the bifunctional electrocatalysis via local charge rearrangement of α-CrOOH-modulated Co@CoMoOx for overall water splitting - Suh-Ciuan Lim; Chao-Lung Chiang; Chun-Kuo Peng; Wen-Bin Wu; Yu-Chang Lin; Yu-Ru Lin; Chi-Liang Chen; Yan-Gu Lin (Chemical Engineering Journal, 2023)

13.2% EQE near-infrared TADF OLED with emission peak at 761 nm - Jing-Wen Tai; Yukun Tang; Kai Zhang; Chen-Zong Yang; Ze-Hui Pan; Yu-Ching Lin; Yu-Wei Shih; Chia-Hsun Chen; Tien-Lung Chiu; Jiun-Haw Lee; Chuan-Kui Wang; Chung-Chih Wu; et al. (Chemical Engineering Journal, 2023)

Sputter-deposited nickel nanoparticles on Kevlar fabrics with laser-induced graphene for efficient solar evaporation - Shuaihang Zhu; Zhiwei Lei; Yuejie Dou; Ching-Wen Lou; Jia-Horng Lin; Jiwei Li (Chemical Engineering Journal, 2023)

Enhancement of an efficient enzyme cocktail from Penicillium consortium on biodegradation of pretreated poplar - Cuiyi Liang; Qiong Wang; Wen Wang; Carol Sze Ki Lin; Yunzi Hu; Wei Qi (Chemical Engineering Journal, 2023)

N-type small molecule electron transport materials with D-A-D conjugated core for non-fullerene organic solar cells - Dan Zhou; Yubing Li; Hehui Zhang; Haolan Zheng; Xingxing Shen; Wen You; Lin Hu; Liangjing Han; Yongfen Tong; Lie Chen (Chemical Engineering Journal, 2023)

Near-infrared I/II emission and absorption carbon dots via constructing localized excited/charge transfer state for multiphoton imaging and photothermal therapy - Wen-Bo Zhao; Dan-Dan Chen; Kai-Kai Liu; Yong Wang; Rui Zhou; Shi-Yu Song; Fu-Kui Li; Lai-Zhi Sui; Qing Lou; Lin Hou; Chong-Xin Shan (Chemical Engineering Journal, 2023)

Unravelling the formation mechanism and performance of nitrogen, sulfur codoped biochar as peroxymonosulfate activator for gatifloxacin removal - Zheng-Yi Choong; Mohamed Faisal Gasim; Kun-Yi Andrew Lin; Tuan Sherwyn Hamidon; Hazwan Hussin; Wen-Da Oh (Chemical Engineering Journal, 2023)

In-situ growth of bimetallic FeCo-MOF on magnetic biochar for enhanced clearance of tetracycline and fruit preservation - Yi-Cai Jiang; Meng-Fan Luo; Zi-Nuo Niu; Si-Yuan Xu; Yue Gao; Yuan Gao; Wen-Juan Gao; Jing-Jing Luo; Rui-Lin Liu (Chemical Engineering Journal, 2023)

Insights into integration of polyhydroxyalkanoates (PHAs) production into wastewater treatment: Comparison of different electron acceptors on system function and PHA-producer enrichment - Baozhen Liu; Qinxue Wen; Long Huang; Zhiqiang Chen; Xiao Lin; Shaojiao Liu (Chemical Engineering Journal, 2023)

Lamellar-structured anodes based on lithiophilic gradient enable dendrite-free lithium metal batteries with high capacity loading and fast-charging capability - Yucheng Liu; Chuang Sun; Yuhao Lu; Xiaoping Lin; Maohua Chen; Yuansen Xie; Chao Lai; Wen Yan (Chemical Engineering Journal, 2023)

Effects of a novel hybrid polymer material on the hydro-mechanical behavior of subgrade silts considering freeze-thaw cycles - Xiao-ning Zhang; Xin-zhuang Cui; Lu-qiang Ding; Ji-yuan Luan; Yi-lin Wang; Peng Jiang; Jian-wen Hao (Cold Regions Science and Technology, 2023)

Osteomodulin protects dental pulp stem cells from cisplatin-induced apoptosis in vitro - Ting Dong; Wen-zhen Lin; Xiao-han Zhu; Ke-yong Yuan; Li-li Hou; Zheng-wei Huang (Stem Cell Reviews and Reports, 2023)

Soil water and salt migration in oasis farmland during crop growing season - Dengke Ma; Zhibin He; Lisha Wang; Wenzhi Zhao; Longfei Chen; Pengfei Lin; Peng Zhao; Wen Wang; Yuan Gao; Jing Li (Journal of Soils and Sediments, 2023)

Effects of Glycogen Synthase Kinase-3 Beta Gene Polymorphisms on the Plasma Concentration of Aripiprazole in Chinese Patients with Schizophrenia: A Preliminary Study - Zhizhong Xu; Chunyan Wen; Yinghua Huang; Qianfa Yuan; Xianhua Zhang; Duoduo Lin; Liangsheng Liu; Wenqiang Wang (Journal of Molecular Neuroscience, 2023)

Andrographolide ameliorates hepatic steatosis by suppressing FATP2-mediated fatty acid uptake in mice with nonalcoholic fatty liver disease - Li-Sha Ran; Ya-Zeng Wu; Yi-Wen Gan; Hong-Lian Wang; Li-Juan Wu; Chun-Mei Zheng; Yao Ming; Ran Xiong; Yong-Lin Li; Shi-Hang Lei; Xue Wang; Xiao-Qing Lao; et al. (Journal of Natural Medicines, 2023)
Excessive intrahepatocellular lipid accumulation or steatosis is caused by abnormal lipid metabolism and a common character of nonalcoholic fatty liver disease (NAFLD), which may progress into cirrhosis and hepatocellular cancer. Andrographolide (Andro) is the primary active ingredient extracted from Andrographis paniculata , showing a protective role against dietary steatosis with the mechanism not fully understood. In this study, we showed that administration of Andro (50, 100, and 200 mg/kg/day for 8 weeks, respectively) attenuated obesity and metabolic syndrome in high-fat diet (HFD)-fed mice with improved glucose tolerance, insulin sensitivity, and reduced hyperinsulinemia, hyperglycemia, and hyperlipidemia. HFD-fed mice presented hepatic steatosis, which was significantly prevented by Andro. In vitro, Andro decreased the intracellular lipid droplets in oleic acid-treated LO2 cells. The selected RT-PCR array revealed a robust expression suppression of the fatty acid transport proteins (FATPs) by Andro treatment. Most importantly, we found that Andro consistently reduced the expression of FATP2 in both the oleic acid-treated LO2 cells and liver tissues of HFD-fed mice. Overexpression of FATP2 abolished the lipid-lowering effect of Andro in oleic acid-treated LO2 cells. Andro treatment also reduced the fatty acid uptake in oleic acid-treated LO2 cells, which was blunted by FATP2 overexpression. Collectively, our findings reveal a novel mechanism underlying the anti-steatosis effect of Andro by suppressing FATP2-mediated fatty acid uptake, suggesting the potential therapeutic application of Andro in the treatment of NAFLD. Graphical abstract

Strength and Failure Behaviors of a Jointed Rock Mass Anchored by Steel Bolts: A Numerical Modeling Study - Hong-Wen Jing; Xu-Xu Yang; Mao-Lin Zhang (Geotechnical and Geological Engineering, 2023)

Dual-response and lysosome-targeted fluorescent probe for viscosity and sulfur dioxide derivatives - Feng Li; Bang-Zhao Zhou; Wen Yao; Shou-Kang Sun; Jun-Ying Miao; Bao-Xiang Zhao; Zhao-Min Lin (Analytica Chimica Acta, 2023)

A two-dimensional disposable full-history time-temperature indicator for cold chain logistics - Wen Shou; Yueliang Wang; Yuanyuan Yao; Lifen Chen; Binyong Lin; Zhenyu Lin; Longhua Guoa (Analytica Chimica Acta, 2023)

Target controlled alternative hybridization chain reaction for fluorescent detection of dual mycotoxins - Qin Ma; Yiyan Lin; Yun Yang; Wenming Yang; Wen Yun; Mingming Zhang; Lizhu Yang (Analytica Chimica Acta, 2023)

Physiological and transcriptome analysis of Mytilus coruscus in response to Prorocentrum lima and microplastics - Xiao-wen Tang; Rong Yu; Mei-hua Fan; Zhi Yang; Zhi Liao; Zong-xin Yang; Chen-ying Xie; Yu-kun Xuan; Jian-xin Wang; Xiao-lin Zhang; Xiao-jun Yan (Frontiers in Marine Science, 2022)
Nowadays, diarrheic shellfish toxicity (DSP) toxin and microplastics (MPs) are commonly found in coastal waters worldwide. Due to their widespread use, their persistence and toxicity, they may induce adverse effects on Mytilus coruscus . However, the underlying toxic mechanisms of DSP and MPs on M. coruscus remain unclear. This study explored the physiological index and transcriptome change of the digestive gland of adult M. coruscus exposed for 3 days to polystyrene (PS) MPs (0.2 mg/L, 90-100 μm) and Prorocentrum lima alone or in combination. The results showed that the CAT activity and MDA content significantly increased, respiration rate and feeding rate significantly decreased. The combination of MPs and P. lima caused more structural damage to the rough surface endoplasmic reticulum and mitochondria in the digestive glands of M. coruscus . The transcriptome analysis showed that 485 and 220 genes were up- and down-regulated, respectively, after exposure to P. lima ; 1,989 up-regulated DEGs and 1,098 down-regulated DEGs were identified after exposure to MP treatment, and 1,004 up-regulated DEGs and 664 down-regulated DEGs were identified after exposure to the combination of P. lima and MPs. The DEGs were mainly enriched in the lysosome, mRNA surveillance pathway, carbon metabolism, the mTOR signaling pathway, the complement and coagulation cascades, and the TNF signaling pathway. The MP, P. lima exposure mainly induced the expression of RNA-binding protein musashi, serine/arginine repetitive matrix protein 1, low affinity immunoglobulin epsilon Fc receptor, toll-like receptor 2, caspase 7, calmodulin, E3 ubiquitin-protein ligase, serine/threonine-protein kinase PRP4, glutathione S-transferase, and heat shock 70 kDa protein. MPs and P. lima poison mainly influence the expression of RNA transport, immune related gene, apoptosis, signal related gene, and antioxidant gene change. The combination of MPs and P. lima has a synergistic toxic effect. This study provides a new insights into its physiological and molecular responses of M. coruscus to MPs and P. lima toxic exposure.

Promoting human rights for Taiwan’s fishermen: Collaboration with the primary source countries of Taiwan’s DWF migrant fishermen - Po-Chih Hung; Hsiao-Chien Lee; Chih-Cheng Lin; Wen-Hong Liu (Frontiers in Marine Science, 2022)
Taiwan is one of the largest distant water fishing (DWF) nations worldwide, and relies largely on the migrant labor to keep costs low. However, this industry has caused Taiwan to be listed in the 2020 “List of Goods Produced by Child Labor or Forced Labor” of the U.S. Department of Labor. In view of this, the Taiwanese government is actively adopting further management measures to supervise the domestic and foreign fishermen agencies. It is because the latter has been involved in many disputes, especially in recruitment, payroll, and labor contracts, which directly or indirectly affect the rights of migrant fishermen. On the other hand, although the C188 Work in Fishing Convention has stregthend the protection of the fishermen’s human rights, it still stays ambiguous in terms of private agency management. That is also why so many disputes have been caused in recent years.This study conducts a comparative analysis of the agency management systems in the primary source countries of Taiwan’s distant water fishing migrant fishermen (that is, Indonesia, the Philippines, and Vietnam), as well as interviews with distant water fishing stakeholders to provide insights on the improvement of agency management and migrant fishermen’s rights in Taiwan. The findings imply that the positive interaction, mutual trust, and understanding of laws and regulations between fishermen’s exporting and importing countries lead to future cross-national collaboration. This study suggests that the Taiwanese government should follow the spirit of the C188 but not be restricted to the Convention texts to amend or formulate regulations and policies of agencies for fully protecting the rights of migrant fishermen.

Effects of oxygen content on gaseous and solid products during molten salt oxidation of cation exchange resins - Yun Xue; Yue-Lin Wang; Yang-Hai Zheng; Yu-Sheng Yang; Wen-Da Xu; Yong-De Yan; Ran Zhao; Qing-Guo Zhang; Xin Liu; Fu-Qiu Ma; Mi-Lin Zhang (Environmental Science and Pollution Research, 2022)

Weakened influence of El Niño–Southern Oscillation on the zonal shift of the South Asian High after the early 1980s - Sixian Cen; Wen Chen; Shangfeng Chen; Lin Wang; Yuyun Liu; Jingliang Huangfu (International Journal of Climatology, 2022)
Previous studies indicated that El Niño–Southern Oscillation (ENSO) significantly impacts the zonal shift of the South Asian High (SAH) in boreal summer. This analysis reveals that the influence of ENSO on the zonal shift of the SAH has experienced a significant interdecadal weakening around the early 1980s. Specifically, ENSO has a significant relation with the SAH's zonal shift before the early 1980s. However, after the early 1980s, the impact of the ENSO on the SAH is weak. We further examined the physical processes for the interdecadal change of the ENSO–SAH relation. It is indicated that interdecadal change of relationship between ENSO and SAH zonal shift is attributable to change in the connection between ENSO and Indian summer monsoon (ISM). Before the early 1980s, ENSO could exert significant impacts on the ISM and lead to significant condensational latent heating anomalies around the northern Indian Peninsula. The atmospheric heating anomalies around the northern Indian Peninsula trigger an atmospheric wave train extending eastward from North Africa toward the Iranian Plateau (IP), which further leads to changes in the zonal location of the SAH. Hence, the ENSO exerts significant impacts on the summer SAH zonal shift. By contrast, after the early 1980s, ENSO had a weak impact on the ISM and could not lead to apparent atmospheric heating anomalies over IP. As such, ENSO has a weak effect on the SAH zonal shift. Further analysis indicates that interannual variation of the SAH zonal shift is related to an atmospheric wave train over mid–high latitudes of Eurasia after the early 1980s.

Administration of the Potential Probiotic Paenibacillus ehimensis NPUST1 Enhances Expression of Indicator Genes Associated with Nutrient Metabolism, Growth and Innate Immunity against Aeromonas hydrophila and Streptococcus indie Infections in Zebrafish (Danio rerio) - Pei-Hui Lin; Sai-Wei Chen; Zhi-Hong Wen; Shao-Yang Hu (Fishes, 2022)
Probiotics as antibiotic alternatives for preventing and controlling infectious diseases are a relatively eco-friendly strategy in aquaculture. The bacteriocin-producing probiotic Paenibacillus ehimensis NPUST1 was isolated from tilapia culture pond water in our previous study. The present study demonstrated that P. ehimensis NPUST1 produced hydrolytic enzymes, including protease, amylase, cellulase, xylanase and lipase. The effects of P. ehimensis NPUST1 on zebrafish nutrient metabolism, growth performance and innate immunity were evaluated by measuring the expression of indicator genes in zebrafish after feeding P. ehimensis NPUST1 at doses of 106 and 107 CFU/g for 8 weeks. There was an obvious increase in the hepatic mRNA expression of carbohydrate metabolism-related genes, including glucokinase, hexokinase 1, glucose-6-phosphatase, and pyruvate kinase, and growth-related genes, including the growth hormone receptor and insulin-like growth factor-1. The expression of the innate immune-related genes including interleukin (IL)-1β, IL-6, IL-15, tumor necrosis factor-α, toll-like receptor (TLR)-1, TLR-4, complement component C3b and lysozyme were significantly increased in P. ehimensis NPUST1-supplemented fish. A significant reduction in cumulative mortality was exhibited in P. ehimensis NPUST1-supplemented fish after infection with Aeromonas hydrophila and Streptococcus iniae. In conclusion, our data suggested that P. ehimensis NPUST1 supplementation in feed could potentially improve nutrient metabolism and growth in addition to enhancing innate immunity and disease resistance against A. hydrophila and S. iniae in zebrafish.

Aloe polysaccharide promotes osteogenesis potential of adipose-derived stromal cells via BMP-2/Smads and prevents ovariectomized-induced osteoporosis - Xue-wei Yao; He-dong Liu; Mao-xian Ren; Tian-lin Li; Wen-kai Jiang; Zhi Zhou; Zhi-yi Liu; Min Yang (Molecular Biology Reports, 2022)
Background Aloe polysaccharide (AP) is a type of an active macromolecule of Aloe vera, which contributes to its function. However, whether AP possesses anti-osteoporosis properties is unknown. Methods Adipose-derived stromal cells were treated with different concentrations of AP. Early and late osteogenesis were, respectively, evaluated by ALP and Alizarin Red S staining. The effect of AP on the processes of adipogenesis inhibition in ADSCs was analyzed by oil red O staining. Western blot was used to assess the expression of osteogenic and adipogenic related factors. Then, Noggin was administered to further confirm the mechanism by which AP promotes the osteogenesis of ADSCs. Finally, 40 female SD rats were classified into a bilateral laparotomy group (Sham group) and three bilateral ovariectomy groups: OVX group, OVX + AP group, and OVX + AP + Noggin group. The bilateral rat femurs were collected to perform micro-CT scanning, HE, Masson trichrome, and Oil red O staining. Results The results indicated that AP could increase ALP expression and calcium deposition. Through molecular mechanisms, AP promotes the protein expression of COL1A1, OPN, and ALP in ADSCs, but downregulates the expression of PPARγ. Also, AP directs ADSCs’ fate by stimulating the BMP2/Smads signaling pathway. In vivo, the rat AP-treated had more trabecular bone than the OVX rat, indicating partial protection from cancellous bone loss after treatment with AP. Conclusion Our results show that AP may promote osteogenesis of ADSCs through BMP-2/Smads signaling pathway and inhibits lipogenic differentiation. Thus, AP might be a promising alternative medicine to treat postmenopausal osteoporosis.

Uncovering expression and functional analysis of newly discovered high-affinity K+ transporter family members from sugarcane - Hai-bin Luo; Cheng-mei Huang; Yuan-wen Wei; Hui-ming Zhu; Hui-qing Cao; Sheng-li Jiang; Zhi-nian Deng; Kai-chao Wu; Lin Xu (Journal of Plant Biochemistry and Biotechnology, 2022)

AIoT-Based Ergometer for Physical Training in Frail Elderly with Cognitive Decline: A Pilot Randomized Control Trial - Chih-Chun Lin; Li-Chieh Kuo; Yu-Sheng Lin; Chia-Ming Chang; Fang Wen Hu; Yi-Jing Chen; Chun-Tse Lin; Fong-Chin Su (Journal of Medical and Biological Engineering, 2022)
Purpose Reduced physical activity is reported in the elderly, especially in institutional residents. Institutionalized older adults exhibit a high prevalence of frailty. In this work, we developed an artificial intelligence of things (AIoT)-based feedback assistive strengthening ergometer (AIFASE), for the physical strengthening of the elderly with intelligent assistance. Methods We conducted a 12-week intervention in a long-term care facility. In total, 16 participants (84.38 ± 6.0 years; 4 males and 12 females) were recruited with 1:1 randomization of exercise to control groups. The muscle strength of the lower extremities, timed up and go test (TUG), and Short-form Physical Performance Battery (SPPB) of the participants were measured. The AIFASE system allows the clinical staff to record the personal physical performance of the elderly and generates personalized exercise prescriptions accordingly. AIFASE also displays the current usage status of all ergometers and the users’ physiological conditions. The algorithms were developed to generate warning alerts when the training workload was too large by personal physiological detection. AIFASE automatically customized the exercise prescription according to the user’s exercise performance. Results After a 12-week AIFASE intervention, the intervention group exhibited significant improvements in the strength of the hip flexor, Semi-Tandem Stand, and Tandem Stand. Conclusion In this study, we developed an AIoT ergometer that delivered customized physical training prescriptions to improve the physical performance of long-term care facility residents. We believe that the application of AIFASE will help improve the quality of institutional care.

Effects of high-temperature stress on photosynthesis of a new variety "SF-2" in Neoporphyra haitanensis - Xiu-Wen Yang; Lin-Bin Huang; Xing-Hong Yan (Journal of Applied Phycology, 2022)

Joint influence of the quasi-biennial oscillation and Indian Ocean basin mode on tropical cyclone occurrence frequency over the western North Pacific - Jingliang Huangfu; Yulian Tang; Lin Wang; Wen Chen; Ronghui Huang; Tianjiao Ma (Climate Dynamics, 2022)

Evaluation of the Madden-Julian Oscillation in Fengyun-3B Polar-Orbiting Satellite Reprocessed OLR Data - Hainan Gong; Wanchun Zhang; Ling Sun; Zizhen Dong; Peng Zhang; Lin Wang; Wen Chen; Renguang Wu (Journal of Meteorological Research, 2022)

Halorussus vallis sp. nov., Halorussus aquaticus sp. nov., Halorussus gelatinilyticus sp. nov., Halorussus limi sp. nov., Halorussus salilacus sp. nov., Halorussus salinisoli sp. nov.: six extremely halophilic archaea isolated from solar saltern, salt lake and saline soil - Xi-Wen Zheng; Zhang-Ping Wu; Ya-Ping Sun; Bei-Bei Wang; Jing Hou; Heng-Lin Cui (Extremophiles, 2022)

Halorientalis salina sp. nov., Halorientalis marina sp. nov., Halorientalis litorea sp. nov.: three extremely halophilic archaea isolated from a salt lake and coarse sea salt - Bei-Bei Wang; Ya-Ping Sun; Zhang-Ping Wu; Xi-Wen Zheng; Jing Hou; Heng-Lin Cui (Extremophiles, 2022)

Impact of salinity origin on microbial communities in saline springs within the Illinois Basin, USA - Linduo Zhao; Hongbo Shao; Li Zhang; Samuel V. Panno; Walton R. Kelly; Tzu‐Yu Lin; Wen‐Tso Liu; Theodore M. Flynn; Peter Berger (Environmental Microbiology, 2022)
Saline springs within the Illinois Basin result from the discharge of deep‐seated evaporated seawater (brine) and likely contain diverse and complex microbial communities that are poorly understood. In this study, seven saline/mineral springs with different geochemical characteristics and salinity origins were investigated using geochemical and molecular microbiological analyses to reveal the composition of microbial communities inhabiting springs and their key controlling factors. The 16S rRNA sequencing results demonstrated that each spring harbours a unique microbial community influenced by its geochemical properties and subsurface conditions. The microbial communities in springs that originated from Cambrian/Ordovician strata, which are deep confined units that have limited recharge from overlying formations, share a greater similarity in community composition and have a higher species richness and more overlapped taxa than those that originated from shallower Pennsylvanian strata, which are subject to extensive regional surface and groundwater recharge. The microbial distribution along the spring flow paths at the surface indicates that 59.8%–94.2% of total sequences in sedimentary samples originated from spring water, highlighting the role of springs in influencing microbiota in the immediate terrestrial environment. The results indicate that the springs introduce microbiota with a high biodiversity into surface terrestrial or aquatic ecosystems, potentially affecting microbial reservoirs in downstream ecosystems.

Numerical Investigation of Depressurization through Horizontal Wells in Methane-Hydrate-Bearing Sediments Considering Sand Production - Xuyang Guo; Yan Jin; Jingyu Zi; Jiaying Lin; Bolong Zhu; Qian Wen; Qi Jing (Journal of Marine Science and Engineering, 2022)
Sand production has been identified as a key reason limiting sustained and commercial gas production in methane-hydrate-bearing sediments. Production tests in Canada and Japan were terminated partially because of excessive sand production in pilot wells. It is meaningful to carry out numerical investigations and sensitivity analyses to improve the understanding of sand production mechanisms during the exploitation of methane hydrates. This study introduces a numerical model to describe the coupled thermal–hydraulic–mechanical–chemical responses and sand production patterns during horizontal well depressurization in methane-hydrate-bearing sediments. The model is benchmarked with a variety of methane hydrate reservoir simulators. Results show that the spatial and temporal evolution patterns of multi-physical fields are different and the hydromechanical evolutions are the fastest. Gas production and sand production rates are oscillatory in the early stages and long-term rates become stable. Gas production is sensitive to rock physical and operational parameters and insensitive to rock mechanical properties such as cohesion. In contrast, sand production is sensitive to cohesion and insensitive to rock physical and operational parameters. Although cohesion does not directly affect gas productivity, gas productivity can be impaired if excessive sand production impedes production operations. This study provides insights into the sand production mechanism and quantifies how relevant parameters affect sand production during the depressurization in methane-hydrate-bearing sediments.

Prolonged electrolysis injures the neural development of zebrafish (Danio rerio) - Chaoqun Zheng; Yan Gao; Jinling Zhu; Lin Gan; Mengmeng Wang; Wen Zhang; Shunqing Yang; Liuyan Yang (Environmental Science and Pollution Research, 2022)

Two new sesquiterpenoid lactone derivatives from Lindera aggregata - Song-Song Wen; Yan Wang; Jia-Ping Xu; Qi Liu; Lei Zhang; Jing Zheng; Lin Li; Na Zhang; Xin Liu; Yu-Wen Xu; Zhen-Liang Sun (Natural Product Research, 2022)

Design of deep-sea chemical data collector for the seafloor observatory network - Bin Lv; Jie Chen; Hai-lin Liu; Chao Liu; Zhao-wen Zhang; Xiao-nan Zhang; Hao Gao; Yu-long Cai (Marine Georesources & Geotechnology, 2022)

Associations of single and multiple organophosphate pesticide exposure with female infertility in the USA: data from the 2015–2018 National Health and Nutrition Examination Survey - Yingying Wu; Xueqiong Weng; Shan Liu; Yuxuan Tan; Huanzhu Liang; Yexin Li; Lin Wen; Qian Chen; Chunxia Jing (Environmental Science and Pollution Research, 2022)

GDH promotes isoprenaline-induced cardiac hypertrophy by activating mTOR signaling via elevation of α-ketoglutarate level - Zhi-Rong Lin; Zhen-Zhen Li; Yan-Jun Cao; Wen-Jing Yu; Jian-Tao Ye; Pei-Qing Liu (Naunyn-Schmiedeberg's Archives of Pharmacology, 2022)

Construction and evaluation of curcumin upconversion nanocarriers decorated with MnO2 for tumor photodynamic therapy - Xinru Chen; Quandong Li; Zipeng Huang; Wen Lin; Yan Ma (Drug Delivery and Translational Research, 2022)

Circular RNA expression profile of systemic lupus erythematosus and its clinical significance as a potential novel biomarker - Wenyu Li; Runge Fan; Cheng Zhou; Yue Wei; Shunsheng Lin; Sijian Wen; Wen Zeng; Wei Hou; Cheng Zhao; Youkun Lin (Genes & Genomics, 2022)
Background Circular RNAs (circRNAs) are a class of endogenous noncoding RNAs that are more abundant, specific, and highly organized than linear RNAs. Increasing evidence supports that circRNAs may serve as diagnostic biomarkers in many diseases, but their potential as biomarkers in systemic lupus erythematosus (SLE) remains unclear. Objective We investigated the critical circRNAs involved in SLE progression and explored their potential application as biomarkers in SLE. Method RNA sequencing was conducted on peripheral blood mononuclear cells (PBMCs) from 4 SLE patients and 4 healthy volunteers. CircRNA profile data were analyzed to identify differentially expressed circRNAs and visualized via R software. After screening, qPCR analysis of target circRNA expression was performed using PBMCs from 31 SLE patients and 35 healthy volunteers. Correlations between circRNA expression levels and the SLEDAI score were assessed via Spearman correlation analysis. Finally, the performance of circRNAs as biomarkers in SLE was examined by receiver operating characteristic curve analysis. Results The result identified six differentially expressed circRNAs between SLE patients and healthy controls: hsa_circ_0006689, hsa_circ_0070562, hsa_circ_0006117, hsa_circ_0007683, hsa_circ_0042519, and hsa_circ_0008647. The validation analysis showed differing relative expression levels of hsa_circ_0007683, hsa_circ_0042519, hsa_circ_0008647, and hsa_circ_0006689 between SLE patients and healthy volunteers (P < 0.05), and hsa_circ_0006689 expression in PBMCs correlated with the SLEDAI score (P < 0.05). Furthermore, addition of hsa_circ_0006689 expression increased the sensitivities of anti-dsDNA antibody and anti-Sm antibody levels for SLE diagnosis (from 29.03 to 61.30% and 32.26–71.00%, respectively). Conclusion Our results suggest hsa_circ_0006689 may be a useful circRNA biomarker for SLE diagnosis and prognosis.

A histological study of vascular wall resident stem cells in venous malformations - Hou-Fu Xia; Wen-Qiang Lai; Gao-Hong Chen; Ye Li; Qi-Hui Xie; Yu-Lin Jia; Gang Chen; Yi-Fang Zhao (Cell and Tissue Research, 2022)

Local temperature increases reduce soil microbial residues and carbon stocks - Xiao‐Min Zeng; Jiao Feng; Dai‐Lin Yu; Shu‐Hai Wen; Qianggong Zhang; Qiaoyun Huang; Manuel Delgado‐Baquerizo; Yu‐Rong Liu (Global Change Biology, 2022)
Warming is known to reduce soil carbon (C) stocks by promoting microbial respiration, which is associated with the decomposition of microbial residue carbon (MRC). However, the relative contribution of MRC to soil organic carbon (SOC) across temperature gradients is poorly understood. Here, we investigated the contribution of MRC to SOC along two independent elevation gradients of our model system (i.e., the Tibetan Plateau and Shennongjia Mountain in China). Our results showed that local temperature increases were negatively correlated with MRC and SOC. Further analyses revealed that rising temperature reduced SOC via decreasing MRC, which helps to explain future reductions in SOC under climate warming. Our findings demonstrate that climate warming has the potential to reduce C sequestration by increasing the decomposition of MRC, exacerbating the positive feedback between rising temperature and CO 2 efflux. Our study also considered the influence of multiple environmental factors such as soil pH and moisture, which were more important in controlling SOC than microbial traits such as microbial life‐style strategies and metabolic efficiency. Together, our work suggests an important mechanism underlying long‐term soil C sequestration, which has important implications for the microbial‐mediated C process in the face of global climate change.

Viscous Flow Fields Induced by the Run-Up of Periodic Waves on Vertical and Sloping Seawalls - Chun-Yuan Lin; Ching-Jer Huang; Tai-Wen Hsu (Journal of Marine Science and Engineering, 2022)
Unsteady two-dimensional Reynolds Averaged Navier-Stokes (RANS) equations coupled with the k−ε turbulence model was developed to simulate the viscous flow field near seawalls. The complex free-surface configuration was captured using the particle level set method (PLSM). An innovative solid-fluid coupling method was employed to mimic the solid-fluid interaction on fixed Cartesian grids. The proposed numerical model was applied to investigate the viscous flow fields induced by periodic waves propagating on three different seawalls, including vertical and steep seawalls, which are commonly designed in Taiwan with slopes of 1:2 and 1:5. The results reveal that the wave run-up height is closely related to Iribarren number and breaking wave. Partial standing wave or asymmetric recirculating cells in front of a steep seawall lose symmetry with increasing slope. The wave pressure on the seawall face increases as the Ursell number or seawall slope increases. The undertow caused by breaking waves has a significant effect on the bottom shear stress in front of the seawall.

Effects of tillage and cropping sequences on crop production and environmental benefits in the North China Plain - Wen-Xuan Liu; Wen-Sheng Liu; Mu-Yu Yang; Yu-Xin Wei; Zhe Chen; Ahmad Latif Virk; Rattan Lal; Xin Zhao; Hai-Lin Zhang (Environmental Science and Pollution Research, 2022)

Experimental study on the process of overtopping breach of concrete-faced sand-gravel dam - Yanlong Li; Wen Qiu; Zuyu Chen; Lifeng Wen; Lin Wang (European Journal of Environmental and Civil Engineering, 2022)

New phenolic glycosides from Anemone chinensis Bunge and their antioxidant activity - Zeng-Guang Zhang; Yuan-Yuan Li; Bin Lin; Pei-Pei Guan; Yu Mu; Wen-Jun Qiao; Jing-Sheng Zhang; Xue-Shi Huang; Li Han (Natural Product Research, 2022)

Comparative assessment of reference crop evapotranspiration models and its sensitivity to meteorological variables in Peninsular Malaysia - Jing Lin Ng; Yuk Feng Huang; Stephen Luo Sheng Yong; Jia Wen Tan (Stochastic Environmental Research and Risk Assessment, 2022)

Predicting Lumbar Vertebral Osteopenia Using LvOPI Scores and Logistic Regression Models in an Exploratory Study of Premenopausal Taiwanese Women - Chun-Wen Chen; Yi-Jui Liu; Shao-Chieh Lin; Chien-Yuan Wang; Wu-Chung Shen; Der-Yang Cho; Tung-Yang Lee; Cheng-Hsuan Juan; Cheng-En Juan; Kai-Yuan Cheng; Chun-Jung Juan (Journal of Medical and Biological Engineering, 2022)
Purpose To propose hybrid predicting models integrating clinical and magnetic resonance imaging (MRI) features to diagnose lumbar vertebral osteopenia (LvOPI) in premenopausal women. Methods This prospective study enrolled 101 Taiwanese women, including 53 before and 48 women after menopause. Clinical information, including age, body height, body weight and body mass index (BMI), were recorded. Bone mineral density (BMD) was measured by the dual-energy X-ray absorptiometry. Lumbar vertebral fat fraction (LvFF) was measured by MRI. LvOPI scores (LvOPISs) comprising different clinical features and LvFF were constructed to diagnose LvOPI. Statistical analyses included normality tests, linear regression analyses, logistic regression analyses, group comparisons, and diagnostic performance. A P value less than 0.05 was considered as statistically significant. Results The post-menopausal women had higher age, body weight, BMI, LvFF and lower BMD than the pre-menopausal women (all P < 0.05). The lumbar vertebral osteoporosis group had significantly higher age, longer MMI, and higher LvFF than the LvOPI group (all P < 0.05) and normal group (all P < 0.005). LvOPISs (AUC, 0.843 to 0.864) outperformed body weight (0.747; P = 0.0566), BMI (0.737; P < 0.05), age (0.649; P < 0.05), and body height (0.5; P < 0.05) in diagnosing LvOPI in the premenopausal women. Hybrid predicting models using logistic regression analysis (0.894 to 0.9) further outperformed all single predictors in diagnosing LvOPI in the premenopausal women ( P < 0.05). Conclusion The diagnostic accuracy of the LvOPI can be improved by using our proposed hybrid predicting models in Taiwanese premenopausal women.

Fracture Mechanical Properties of Three—Dimensional Irregular Sandstone Particles Based on Digital-Image - Kai-wen Shi; Yu-jun Zuo; Wen-ji-bin Sun; Hao Liu; Jian-yun Lin; Tao-tao Li; Bin Chen; Lu-lin Zheng (Geotechnical and Geological Engineering, 2022)

Clinical profiles and antimicrobial resistance patterns of invasive Salmonella infections in children in China - Wen Song; Qingwen Shan; Yue Qiu; Xianyao Lin; Chunhui Zhu; Zhiqiang Zhuo; Caihong Wang; Jianning Tong; Rui Li; Chaomin Wan; Yu Zhu; Minxia Chen; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2022)
Invasive Salmonella infections result in a significant burden of disease including morbidity, mortality, and financial cost in many countries. Besides typhoid fever, the clinical impact of non-typhoid Salmonella infections is increasingly recognized with the improvement of laboratory detection capacity and techniques. A retrospective multicenter study was conducted to analyze the clinical profiles and antimicrobial resistance patterns of invasive Salmonella infections in hospitalized children in China during 2016–2018. A total of 130 children with invasive Salmonella infections were included with the median age of 12 months (range: 1–144 months). Seventy-nine percent of cases occurred between May and October. Pneumonia was the most common comorbidity in 33 (25.4%) patients. Meningitis and septic arthritis caused by nontyphoidal Salmonella (NTS) infections occurred in 12 (9.2%) patients and 5 (3.8%) patients. Patients < 12 months (OR: 16.04) and with septic shock (OR: 23.4), vomit (OR: 13.33), convulsion (OR: 15.86), C-reactive protein (CRP) ≥ 40 g/L (OR: 5.56), and a higher level of procalcitonin (PCT) (OR: 1.05) on admission were statistically associated to an increased risk of developing meningitis. Compared to 114 patients with NTS infections , 16 patients with typhoid fever presented with higher levels of CRP and PCT ( P < 0.05). The rates of resistance to ampicillin, sulfamethoxazole/trimethoprim, ciprofloxacin, and ceftriaxone among Salmonella Typhi and NTS isolates were 50% vs 57.3%, 9.1% vs 24.8%, 0% vs 11.2%, and 0% vs 9.9%, respectively. NTS has been the major cause of invasive Salmonella infections in Chinese children and can result in severe diseases. Antimicrobial resistance among NTS was more common.

Organic–inorganic calcium lignosulfonate compounds for soil acidity amelioration - Fei Kang; Qi-lin Lv; Jin Liu; Yun-shan Meng; Zi-he Wang; Xue-qin Ren; Shu-wen Hu (Environmental Science and Pollution Research, 2022)

Relationship between urinary dichlorophenols and cognitive function among people over 60 years old from NHANES - Xueqiong Weng; Huanzhu Liang; Kun Liu; Jingmin Chen; Qiaoyuan Fei; Shan Liu; Xinrong Guo; Lin Wen; Yingying Wu; Zhiqiang Nie; Chunxia Jing (Environmental Science and Pollution Research, 2022)

Correction to: Effects of cryopreservation on the ultrastructure of coral larvae - Luca Cirino; Sujune Tsai; Li-Hsueh Wang; Wen-Chung Hsieh; Cheng-Liang Huang; Zhi-Hong Wen; Chiahsin Lin (Coral Reefs, 2022)

Maintenance of Epstein-Barr virus latency through interaction of LMP2A with CXCR4 - Ni Qin; Yan Zhang; Lin Xu; Wen Liu; Bing Luo (Archives of Virology, 2022)

Toxicokinetics and metabolism of deoxynivalenol in animals and humans - Yu Sun; Jun Jiang; Peiqiang Mu; Ruqin Lin; Jikai Wen; Yiqun Deng (Archives of Toxicology, 2022)

Modeling of rupture using strong motion generation area: a case study of Hualien earthquake (Mw 6.1) occurred on April 18, 2019 - Saurabh Sharma; Anand Joshi; Sandeep; Che-Min Lin; Chun-Hsiang Kuo; Kuo-Liang Wen; Sandeep Singh; Mukat Lal Sharma; Mohit Pandey; Jyoti Singh (Acta Geophysica, 2022)

Determining In-Situ Stress State by Anelastic Strain Recovery Method Beneath Xiamen: Implications for the Coastal Region of Southeastern China - Chongyuan Zhang; Weiren Lin; Manchao He; Zhigang Tao; Wen Meng (Rock Mechanics and Rock Engineering, 2022)

Altered Retinal Dopamine Levels in a Melatonin-proficient Mouse Model of Form-deprivation Myopia - Kang-Wei Qian; Yun-Yun Li; Xiao-Hua Wu; Xue Gong; Ai-Lin Liu; Wen-Hao Chen; Zhe Yang; Ling-Jie Cui; Yun-Feng Liu; Yuan-Yuan Ma; Chen-Xi Yu; Furong Huang; et al. (Neuroscience Bulletin, 2022)

The fibroblast growth factor receptor antagonist SSR128129E inhibits fat accumulation via suppressing adipogenesis in mice - Xinzhi Zhang; Xin Wen; Geng Hu; Qiang Zhang; Qianying Sun; Yanxin Jia; Yan Liu; Hai Lin; Haifang Li (Molecular Biology Reports, 2022)

Insights into the fates of plasmids and antimicrobial resistance genes during swine manure treatment and related factors based on plasmidome and metagenome analyses - Junrui Shui; Hongmei Tuo; Jinxin Liu; Xialan Zhang; Jingyi Feng; Yuxuan Feng; Wen Su; Cong Lin; Haoyu Zhang; Zunfang Tu; Hongning Wang; Anyun Zhang (Environmental Science and Pollution Research, 2022)

Impacts of Mercury Exposure Levels and Sources on the Demethylation of Methylmercury Through Human Gut Microbiota - Xian-Feng Yang; Shao-Chen Yang; Fu-Li Wen; Lin Feng; Bo Meng; Hai-Yan Hu; Bao-Lin Wang; Jun Li; Alexandre J. Poulain; Ping Li (Bulletin of Environmental Contamination and Toxicology, 2022)

Effect of Zn2+-Cu2+ combined heavy metal on mechanical properties and microstructure of clayey soil - Qiang Ma; Nian-ze Wu; Heng-lin Xiao; Wen-tao Li; Jun-chen Xiang (Journal of Mountain Science, 2022)

Effect of confining pressure on the fracture mechanical properties of multi-particle sandstone - Kai-wen Shi; Yu-jun Zuo; Wenjibin Sun; Hao Liu; Chao Pan; Taotao Li; Bin Chen; Jian-yun Lin (Arabian Journal of Geosciences, 2022)

Ancylostoma ceylanicum Infection in a Miniature Schnauzer Dog Breed - Xu-Hui Lin; Hai-Ming Cai; Zhuan-Qiang Yan; Shen-Quan Liao; Min-Na Lv; Cai-Yan Wu; Juan Li; Jun-Jing Hu; Wen-Wan Xiao; Jian-Fei Zhang; Nan-Shan Qi; Ming-Fei Sun (Acta Parasitologica, 2022)

Hydrodynamic effects of large-scale suspended mussel farms: Field observations and numerical simulations - Wei Zhong; Jun Lin; Qingping Zou; Ying Wen; Wei Yang; Guanlin Yang (Frontiers in Marine Science, 2022)
The hydrodynamic effects of the largest suspended mussel farms in the East China Sea near Gouqi Island, was investigated using a high-resolution 3D ocean model and field observations. To capture the 3D farm effects on hydrodynamics, an additional depth dependent momentum sink term was introduced in the model. The model results compared well with the field observations. The present model and observational results indicate that the presence of farms reduces the flow by more than 79%, 55%, and 34% in the upper, middle, and bottom layers at the farm center, respectively. According to the harmonic analysis of predicted current, mussel farms reduce the magnitude of the semidiurnal tidal current and also alter the magnitude and direction of the diurnal tidal current. The blockage by the farm weakens the Eulerian residual tidal current within the farm in the NE-SW direction, while strengthens that at the edge of the farm in the SE-NW direction. Cross sections, Sec1 and Sec2 are perpendicular to these two major residual currents and intercept with the center of the farm from SE to NW and from NE to SW respectively. The farm effect on the total water flux over a month through the Sec2 displays a semi-lunar periodic oscillation and is one order of magnitude smaller than that at Sec1. An asymmetry tidal current was observed in the farm north of Gouqi Island. The field observation of vertical profiles of current suggests that the thickness of surface canopy boundary layer can reach 5 m upstream from the farm during flood tide, increases gradually downstream up to 10 m under the cumulative influences of the farm. And a wake zone was observed downstream from the farm during flood tide. Better understanding of farm-induced hydrodynamic effects provides insight into how to optimize farm layouts based on local hydrodynamics, to maximize farm productivity and minimize environmental impacts.

PTEN-induced kinase 1 enhances the reparative effects of bone marrow mesenchymal stromal cells on mice with renal ischaemia/reperfusion-induced acute kidney injury - Chenyu Lin; Wen Chen; Yong Han; Yujie Sun; Xiaoqiong Zhao; Yuan Yue; Binyu Li; Wenmei Fan; Tao Zhang; Li Xiao (Human Cell, 2022)
Acute kidney injury (AKI) is a common severe acute syndrome caused by multiple factors and is characterized by a rapid decline in renal function during a short period. Bone marrow mesenchymal stromal cells (BMSCs) are effective in treating AKI. However, the mechanism of their beneficial effects remains unclear. PTEN-induced kinase 1 (PINK1) may play an important role in kidney tissue repair. In this study, we explored the effect of PINK1 overexpression on enhancing BMSC-mediated repair of AKI. In this study, ischaemia/reperfusion-induced AKI (IRI-AKI) in mice and a hypoxia-reoxygenation model in cells were established, and the indices were examined by pathology and immunology experiments. After ischaemia/reperfusion, PINK1 overexpression reduced apoptosis in injured kidney tissue cell, decreased T lymphocyte infiltration, increased macrophage infiltration, and alleviated the inflammatory response. PINK1 relieved the stress response of BMSCs and renal tubular epithelial cells (RTECs), reduced apoptosis, altered the release of inflammatory factors, and reduced the proliferation of peripheral blood mononuclear cells (PBMCs). In conclusion, BMSCs and RTECs undergo stress responses in response to hypoxia, inflammation and other conditions, and overexpressing PINK1 in BMSCs could enhance their ability to resist these stress reactions. Furthermore, PINK1 overexpression can regulate the distribution of immune cells and improve the inflammatory response. The regulation of mitochondrial autophagy during IRI-AKI maintains mitochondrial homeostasis and protects renal function. The results of this study provide new strategies and experimental evidence for BMSC-mediated repair of IRI-AKI.

Underestimation of biogenic silica sinking flux due to dissolution in sediment traps: A case study in the South China Sea - Wen Liang; Lihua Ran; Zhi Yang; Martin G. Wiesner; Yuzhao Liang; Lin Sun; Jianfang Chen (Frontiers in Marine Science, 2022)
The dissolved silicate concentrations in the supernatant of sediment trap sampling bottles retrieved from deep water (1000-3000 m) at four stations in the South China Sea (SCS) were measured to calculate the underestimated flux of biogenic silica (bSi) in sinking particles due to bSi dissolution. High dissolved silicate concentrations in the supernatant, ranging from 122.6 to 1365.8 μmol/L, indicated significant dissolution of particulate bSi in the sampling bottles. Underestimation of the bSi flux in the SCS by ~2% to ~34% (average: ~10%) due to bSi dissolution was revealed, and the degree of underestimation increased with decreasing total bSi flux. The amount of bSi dissolved within the sampling series at each station was generally positively correlated with dissolution time and to a certain extent influenced by the bSi amount collected by the sampling bottles under a low bSi sinking flux. Apparently stronger bSi dissolution was found at two of the four stations due to relatively high bSi dissolution rates, which were possibly related to a higher reactive surface area of the bSi or bacterial activity. Overall, our results demonstrated that the considerable bSi dissolution in sediment trap sampling bottles should not be ignored, especially in the low-productivity oligotrophic ocean, and bSi flux calibration via measurement of the dissolved silicate in sampling bottles is necessary. To reduce bSi flux underestimation due to the deployment of time-series sediment traps, larger-volume sampling bottles should be avoided in the oligotrophic open ocean, and sinking particle samples should be analyzed as soon as the sediment traps are recovered.

Lignans and phenylpropanoids from the roots of Ficus hirta and their cytotoxic activities - Xian-Sheng Ye; Wen-Jing Tian; Xiang-Zhong Liu; Mi Zhou; De-Quan Zeng; Ting Lin; Guang-Hui Wang; Xin-Sheng Yao; Hai-Feng Chen (Natural Product Research, 2022)

The Failure and River Blocking Mechanism of Large-Scale Anti-dip Rock Landslide Induced by Earthquake - Wen-Jie Xu; Lin Wang; Kai Cheng (Rock Mechanics and Rock Engineering, 2022)

The scaling of leaf nitrogen and phosphorus along a phosphorus availability gradient in a subtropical forest - Jiahao Wen; Janice Brahney; Yaoben Lin; Zhiliang Ma; Ningxiao Sun; Ji Zheng; Huawei Ji; Hongzhang Kang; Baoming Du; Guopeng Liang; Muhammad Umair; Chunjiang Liu (Plant Ecology, 2022)

Applications, Challenges, and Outlook for PBPK Modeling and Simulation: A Regulatory, Industrial and Academic Perspective - Wen Lin; Yuan Chen; Jashvant D. Unadkat; Xinyuan Zhang; Di Wu; Tycho Heimbach (Pharmaceutical Research, 2022)

Correction to: Exosome-Derived lncRNA NEAT1 Exacerbates Sepsis-Associated Encephalopathy by Promoting Ferroptosis Through Regulating miR-9-5p/ TFRC and GOT1 Axis - Xue-biao Wei; Wen-qiang Jiang; Ju-hao Zeng; Lin-qiang Huang; Hong-guang Ding; Yuan-wen Jing; Yong-li Han; Yi-chen Li; Sheng-long Chen (Molecular Neurobiology, 2022)

Chemical and biological diversity of new natural products from marine sponges: a review (2009–2018) - Li-Li Hong; Ya-Fang Ding; Wei Zhang; Hou-Wen Lin (Marine Life Science & Technology, 2022)
Marine sponges are productive sources of bioactive secondary metabolites with over 200 new compounds isolated each year, contributing 23% of approved marine drugs so far. This review describes statistical research, structural diversity, and pharmacological activity of sponge derived new natural products from 2009 to 2018. Approximately 2762 new metabolites have been reported from 180 genera of sponges this decade, of which the main structural types are alkaloids and terpenoids, accounting for 50% of the total. More than half of new molecules showed biological activities including cytotoxic, antibacterial, antifungal, antiviral, anti-inflammatory, antioxidant, enzyme inhibition, and antimalarial activities. As summarized in this review, macrolides and peptides had higher proportions of new bioactive compounds in new compounds than other chemical classes. Every chemical class displayed cytotoxicity as the dominant activity. Alkaloids were the major contributors to antibacterial, antifungal, and antioxidant activities while steroids were primarily responsible for pest resistance activity. Alkaloids, terpenoids, and steroids displayed the most diverse biological activities. The statistic research of new compounds by published year, chemical class, sponge taxonomy, and biological activity are presented. Structural novelty and significant bioactivities of some representative compounds are highlighted. Marine sponges are rich sources of novel bioactive compounds and serve as animal hosts for microorganisms, highlighting the undisputed potential of sponges in the marine drugs research and development.

Transport process and mechanism of the Hongshiyan rock avalanche triggered by the 2014 Ludian earthquake, China - Shi-lin Zhang; Yue-ping Yin; Hai-bo Li; Wen-pei Wang; Jia-wen Zhou (Landslides, 2022)

Temporal specificity of IL-6 knockout in enhancing the thermogenic capability of brown adipose tissue - Mei Dong; Cheng Gao; Yanxin Jia; Weijia Xu; Yan Liu; Xin Wen; Qingxin Liu; Hai Lin; Haifang Li (Journal of Physiology and Biochemistry, 2022)

Correction to: Higher sequestration of wheat versus maize crop carbon in soil under rotations - Zheng-Rong Kan; Shou-Wei Han; Wen-Xuan Liu; Xin Zhao; Rattan Lal; Hai-Lin Zhang (Environmental Chemistry Letters, 2022)

PLXDC2 enhances invadopodium formation to promote invasion and metastasis of gastric cancer cells via interacting with PTP1B - Bin Wu; Yan-xia Wang; Jun-jie Wang; Dong-fang Xiang; Meng-si Zhang; Ze-xuan Yan; Wen-ying Wang; Jing-ya Miao; Xi Lan; Jia-jia Liu; Zheng-yan Li; Chuan Li; et al. (Clinical & Experimental Metastasis, 2022)
Plexin-domain containing 2 (PLXDC2) has been reported as an oncoprotein in several human malignancies. However, its expression and roles in gastric cancer remain largely unclear. In this study, we found that PLXDC2 was highly expressed in gastric cancer tissues, and the expression levels were positively correlated with clinicopathological features, but negatively with the patients’ outcome. Cox regression analysis identified PLXDC2 as an independent prognostic indicator for the patients. Knockdown of PLXDC2 markedly suppressed the in vitro invasion and in vivo metastasis of gastric cancer cells, while overexpression of PLXDC2 resulted in opposite effects. Mechanistically, PLXDC2 enhanced the level of phosphorylated Cortactin (p-Cortactin) by physically interacting with protein tyrosine phosphatase 1B (PTP1B), an important dephosphorylase, to prevent its dephosphorylating of p-Cortactin, thereby promoting the formation of invadopodia. Collectively, our results indicate that PLXDC2 contributes to the invasion and metastasis of gastric cancer by inhibiting PTP1B to facilitate the invadopodium formation, and may serve as a potential prognostic biomarker and a therapeutic target for this disease.

Association of cognitive impairment and reduced cortical thickness in prefrontal cortex and anterior cingulate cortex with treatment-resistant depression - Mu-Hong Chen; Wan-Chen Chang; Pei-Chi Tu; Wei-Chen Lin; Cheng-Ta Li; Wen-Sheng Huang; Ya-Mei Bai; Shih-Jen Tsai; Tung-Ping Su (Brain Imaging and Behavior, 2022)

A multi-step nitrifying microbial enrichment to remove ammonia and nitrite in brackish aquaculture systems - Dao Thi Anh Tuyet; Le Minh Hiep; Ha Thi Binh; Le Thanh Huyen; Sen-Lin Tang; Pei-Wen Chiang; Do Manh Hao (Biodegradation, 2022)

Three new sesquiterpene lactones from the whole plants of Elephantopus scaber - Ding-Chai Lin; Qing Tang; Xue-Fang Zhuo; Wen-Zhi Wang; Can-Jie Li; Guang-Kai Kuang; Zhong-Nan Wu; Yu-Bo Zhang; Guo-Cai Wang; Yao-Lan Li (Natural Product Research, 2022)

Isolation and identification of two new sargentodoxosides from Sargentodoxa cuneata and their agonistic effects against FXR - Wen Zhang; Cheng-Peng Sun; Yu-Lin Peng; Wen-Yu Zhao; Zheng-Yue Wang; Jing Ning; Xia Lv; Zhen-Long Yu; Shuang Zhou; Wei Peng; Bang-Jiang Fang; Xiao-Chi Ma (Natural Product Research, 2022)

Chlorophyll fluorescence and grain filling characteristic of wheat (Triticum aestivum L.) in response to nitrogen application level - Hafeez Noor; Min Sun; Hussah I. M. Algwaiz; Alam Sher; Sajid Fiaz; KOTB A. Attia; Shabir Hussain Wani; Muneera D. F. AlKahtani; Latifa Al Husnain; Wen Lin; Zhiqiang Gao (Molecular Biology Reports, 2022)

Lipofundin mediates major inhibition of intravenous propofol on phorbol myristate acetate and Escherichia coli-induced neutrophil extracellular traps - Ming-Shan Chen; Kung-Ssu Yang; Wen-Chun Lin; Chien-Liang Fang; Hsin-Fu Chen; Shew-Meei Sheu (Molecular Biology Reports, 2022)

Correction to: Exercise Rehabilitation and/or Astragaloside Attenuate Amyloid-beta Pathology by Reversing BDNF/TrkB Signaling Deficits and Mitochondrial Dysfunction - Yu-Lin Wang; Chung-Ching Chio; Shu-Chun Kuo; Chao-Hung Yeh; Jui-Ti Ma; Wen-Pin Liu; Mao-Tsun Lin; Kao-Chang Lin; Ching-Ping Chang (Molecular Neurobiology, 2022)

Preliminary establishment of a mass movement warning system for Taiwan using the soil water index - Chi-Wen Chen; Ching Hung; Guan-Wei Lin; Jun-Jih Liou; Shih-Yao Lin; Hsin-Chi Li; Yung-Ming Chen; Hongey Chen (Landslides, 2022)

Dapagliflozin protects against doxorubicin-induced cardiotoxicity by restoring STAT3 - Wei-Ting Chang; Jhih-Yuan Shih; Yu-Wen Lin; Zhih-Cherng Chen; Wei-Chih Kan; Tsung-Hsien Lin; Chon-Seng Hong (Archives of Toxicology, 2022)

Effects of dietary nucleotides on growth performance, immune response, intestinal morphology and disease resistance of juvenile largemouth bass, Micropterus salmoides - Xiao‐chun Chen; Xiao‐quan Huang; Yi‐wen Tang; Lei Zhang; Feng Lin (Journal of Fish Biology, 2022)
An 8 week feeding trial was carried out to investigate the effects of dietary nucleotides on growth performance, intestinal morphology, immune response and disease resistance of juvenile largemouth bass, Micropterus salmoides . Five grades of dietary nucleotide levels were designed as 0, 0.2, 0.4, 0.8 and 1.2 g kg −1 , respectively. Each group had 3 replicates, with 40 fish in each replicate. After the feeding experiment, 15 fish from each tank were infected with Aeromonas hydrophila for 14 days. The results indicated that fish fed the diets containing 0.4, 0.8 and 1.2 g kg −1 nucleotides had higher growth performance and feed utilization than those fed the control diet. Nonetheless, there were no significant differences in survival between all the groups, although fish fed the diets with all‐level nucleotides obtained higher survival than those fed the control diet. Dietary nucleotides significantly affected the superoxide dismutase, acid phosphatase and catalase activities in serum but not the malondialdehyde content. Fish fed the 0.4 g kg −1 nucleotide diets had the highest fold height, enterocyte height and muscular layer thickness significantly. The average mortality of largemouth bass infected with A. hydrophila was significantly influenced by dietary nucleotides. The mortality was significantly higher in the control group (91.11%) and 0.02% nucleotide group (73.11%) followed by the other groups and lowest in the 0.8 g kg −1 nucleotide group. In summary, dietary 0.4–0.8 g kg −1 nucleotides promoted growth performance, enhanced immunity and improved intestinal morphology and disease resistance of largemouth bass.

Super droughts over East Asia since 1960 under the impacts of global warming and decadal variability - Lin Wang; Wen Chen; Qiang Fu; Gang Huang; Qiulin Wang; Chakrit Chotamonsak; Atsamon Limsakul (International Journal of Climatology, 2022)
In the last decade, a sequence of once‐in‐50 year or even once‐in‐100 year high‐impact drought events have hit East Asia. By defining a super drought with the Standardized Precipitation Evaporation Index for the time scales of 3, 6, 12 and 24 months all below −1.5, this study aims to examine the changes in super droughts and the underlying mechanism over East Asia in the past 60 years, putting the recent high‐impact droughts in the context. Super droughts in the last 10 years over East Asia have been the most expansive, with two hotspots located in the Transitional Climate Zone (TCZ) and the Southeast Asian region (SEA) regions, together accounting for 2/3 of the total. The seasonal distribution characterizes the largest contribution from summer followed by autumn and then spring and winter. Super droughts over TCZ peak in the recent two decades, which are primarily driven by the increase in potential evaporation (PET) contributing 41 and 80% in the first and second 10 years, respectively. It turns out that global warming signal can explain more than 90% of this PET increase. Over SEA, the recent decade and the period around 1990 saw the most widespread super droughts that were not spatially uniformly distributed but clustered in three subregions. Different from TCZ, the precipitation rather than PET is the most influential in governing super droughts over SEA. Out of the total variability in precipitation, about half of the super droughts in the recent decade is caused by decadal variability, while the trend mode has negligible influence.

Genetic Diversity Evaluation and Population Structure Analysis of Red Swamp Crayfish (Procambarus clarkii) from Lakes and Rice Fields by SSR Markers - Xin-Fen Guo; Min Liu; Yu-Lin Zhou; Wen-Yu Wei; Zhi Li; Li Zhou; Zhong-Wei Wang; Jian-Fang Gui (Fishes, 2022)
The red swamp crayfish (Procambarus clarkii) is an important aquatic animal and has developed as a popular aquaculture species in China. In this study, a total of 72,839 SSR motifs were identified from transcriptional data, and 20 microsatellite markers of them were finally developed to assess the genetic diversities of seven wild populations from natural lakes and nine cultured populations from rice fields. Genetic diversity was slightly higher in the cultured populations than in the wild populations. The degree of genetic differentiation between cultured populations is slight, while a moderate to a large degree of genetic differentiation between wild populations and most of the variations occurred within individuals (79%). The analysis of cluster, principal coordinate analysis and STRUCTURE were similar, and they showed that isolation-by-distance pattern was not significant. The microsatellite markers developed in this study can not only be used for genetic monitoring of population but also provide important information for the management of breeding and cultured population in red swamp crayfish.

Biflavonoids from the twigs and leaves of Cephalotaxus oliveri Mast. and their α -glucosidase inhibitory activity - Min Song; Tong Xiao; Qiu-Shuang Wu; Hang Fai Kwok; Ging Chan; Li-Gen Lin; Xiao-Qi Zhang; Wen-Cai Ye; Sheng-Jiang He; Qing-Wen Zhang (Natural Product Research, 2022)

Ergosterol peroxide: an effect-directed detecting method from Anoectochilus elwesii and evaluation of anticancer activity - Yanduan Lin; Bingqin Wen; Ziwei Zhang; Jinyan Cai (Natural Product Research, 2022)

Recent developments in vibrational spectral analyses for dynamically assessing and monitoring food dehydration processes - Yuqiao Ren; Xiaohui Lin; Tong Lei; Da-Wen Sun (Critical Reviews in Food Science and Nutrition, 2022)

Vegetation dynamics and their response to Holocene climate change derived from multi-proxy records from Wangdongyang peat bog in southeast China - Lin Zhao; Chunmei Ma; Zhenming Wen; Wei Ye; Guangchun Shang; Lingyu Tang (Vegetation History and Archaeobotany, 2022)

Transcriptome Changes Induced by Botrytis cinerea Stress and Weighted Gene Co-expression Network Analysis (WGCNA) in Actinidia chinensis - Zhe-Xin Li; Wen-Lin Zhang; Deng-Wei Jue; Xia Liu; Yu-Song Jiang; Jian-Min Tang (Plant Molecular Biology Reporter, 2022)