Exosomal MiR-381 from M2-polarized macrophages attenuates urethral fibroblasts activation through YAP/GLS1-regulated glutaminolysis - Ye-Hui Chen; Yi-Cheng Xu; Ting-Ting Lin; Hang Chen; Ru-Nan Dong; Feng-Ping Cai; Zhi-Bin Ke; Jia-Yin Chen; Yong Wei; Qing-Shui Zheng; Xue-Yi Xue; Ning Xu (Inflammation Research, 2023)

Potential response of dark carbon fixation to global warming in estuarine and coastal waters - Lin Qi; Yanling Zheng; Lijun Hou; Bolin Liu; Jie Zhou; Zhirui An; Li Wu; Feiyang Chen; Zhuke Lin; Guoyu Yin; Hongpo Dong; Xiaofei Li; et al. (Global Change Biology, 2023)
Dark carbon fixation (DCF), through which chemoautotrophs convert inorganic carbon to organic carbon, is recognized as a vital process of global carbon biogeochemical cycle. However, little is known about the response of DCF processes in estuarine and coastal waters to global warming. Using radiocarbon labelling method, the effects of temperature on the activity of chemoautotrophs were investigated in benthic water of the Yangtze estuarine and coastal areas. A dome‐shaped thermal response pattern was observed for DCF rates (i.e., reduced rates at lower or higher temperatures), with the optimum temperature ( T opt ) varying from about 21.9 to 32.0°C. Offshore sites showed lower T opt values and were more vulnerable to global warming compared with nearshore sites. Based on temperature seasonality of the study area, it was estimated that warming would accelerate DCF rate in winter and spring but inhibit DCF activity in summer and fall. However, at an annual scale, warming showed an overall promoting effect on DCF rates. Metagenomic analysis revealed that the dominant chemoautotrophic carbon fixation pathways in the nearshore area were Calvin‐Benson‐Bassham (CBB) cycle, while the offshore sites were co‐dominated by CBB and 3‐hydroxypropionate/4‐hydroxybutyrate cycles, which may explain the differential temperature response of DCF along the estuarine and coastal gradients. Our findings highlight the importance of incorporating DCF thermal response into biogeochemical models to accurately estimate the carbon sink potential of estuarine and coastal ecosystems in the context of global warming.

A green synthesized medicine residue carbon-based iron composite for the removal of chromium (VI) and cadmium (II): Performance, kinetics and mechanism - Fa-Ming Diao; Man-Li Chen; Lin-Yin Tong; Ying-Nan Chen; Zeng-Hui Diao (Environmental Science and Pollution Research, 2023)

Fabrication of a SnO2–Sb electrode with TiO2 nanotube array as the middle layer for efficient electrochemical oxidation of amaranth dye - Daying Chen; Lin Zhao; Danning Chen; Pengfei Hou; Jiashu Liu; Chuanbin Wang; Moses Akintayo Aborisade; Meilin Yin; Yongkui Yang (Chemosphere, 2023)

Numerical investigation of submerged flexible vegetation dynamics and wave attenuation under combined waves and following currents - Kai Yin; Ming Lin; Sudong Xu; Jianxin Hao; Liuyan Mao; Mengqi Li (Ocean Engineering, 2023)

Crustal accretion in a slow-spreading center of Meso-Tethyan Ocean: Constraints from cumulates in the Dongco ophiolite (Central Tibet) - Xiao-Ni Li; Wei-Qi Zhang; Tong Liu; Chang Zhang; Zhen Zhang; Yin-Zheng Lin; Chuan-Zhou Liu (Lithos, 2023)

Neonicotinoids residues in cow milk and health risks to the Chinese general population - Xin Wei; Yanan Pan; Zixiong Tang; Qingqi Lin; Yanqi Jiang; Jingyuan Chen; Weixuan Xian; Renli Yin; Adela Jing Li; Rongliang Qiu (Journal of Hazardous Materials, 2023)

Corrigendum to “Mechanism of PM2.5-induced human bronchial epithelial cell toxicity in central China” [J Hazard Mater 396 (2020) 122747] - Shuyin Duan; Meihua Zhang; Yaqiong Sun; Zhenya Fang; Hefeng Wang; Shuxian Li; Yanze Peng; Juan Li; Junxia Li; Jiaqi Tian; Haoyu Yin; Sanqiao Yao; et al. (Journal of Hazardous Materials, 2023)

Racial differences in the associations of urinary phthalate metabolites with depression risk - Jilei Lin; Siying Cheng; Jing Zhang; Liebin Zhao; Shuhua Yuan; Lei Zhang; Yong Yin (Environmental Research, 2023)

Overturning collapse responses of RC frame-shear wall structures induced by failure of vertical members - Xiao-Jing Yin; Bin Zhang; Qian-Qian Yu; Xiang-Lin Gu (Engineering Structures, 2023)

Paleoproterozoic accretion and assembly of the Western Block of North China: A new model - Changqing Yin; Guochun Zhao; Wenjiao Xiao; Shoufa Lin; Rui Gao; Jian Zhang; Jiahui Qian; Peng Gao; Hengzhong Qiao; Wenxuan Li (Earth-Science Reviews, 2023)

Ultralow Ru loading RuO2-TiO2 with strong oxide-support interaction for efficient chlorine evolution and ammonia-nitrogen-elimination - Mengchen Hu; Tianqi Yu; Kexin Tan; Anchao Zhou; Lin Luo; Shibin Yin (Chemical Engineering Journal, 2023)

Cartilage-targeting mRNA-lipid nanoparticles rescue perifocal apoptotic chondrocytes for integrative cartilage repair - Xinning Yu; Tengjing Xu; Huimin Shi; Jianqiao Hong; Xiaoqiang Jin; Le Cao; Jiajie Wang; Yunting Lin; Zongyou Pan; Siheng Wang; Jinghua Fang; Kaiwang Xu; et al. (Chemical Engineering Journal, 2023)

Superior efficiency hydrogen peroxide production in acidic media through epoxy group adjacent to Co-O/C active centers on carbon black - Jili Yuan; Hao Yin; Xin Ge; Ronglan Pan; Caijuan Huang; Dechao Chen; Lin Hu; Haibo Xie (Chemical Engineering Journal, 2023)

Betaine regulates adipogenic and osteogenic differentiation of hAD-MSCs - Yue Jing; Jian Zhou; Fenghua Guo; Lin Yu; Xiaomeng Ren; Xiushan Yin (Molecular Biology Reports, 2023)

Consistent differences in brain structure and functional connectivity in high-altitude native Tibetans and immigrants - Xinjuan Zhang; Weiwei Xie; Wenrui Du; Yanqiu Liu; Jianzhong Lin; Wu Yin; Lihui Yang; Fengjuan Yuan; Ran Zhang; Haipeng Liu; Hailin Ma; Jiaxing Zhang (Brain Imaging and Behavior, 2023)

Conservation and sustainable development of coastal species of horticultural importance: insights from genetic and environmental patterns at spatio-temporal scale - Achyut Kumar Banerjee; Jiakai Wang; Hui Feng; Yuting Lin; Xinru Liang; Minghui Yin; Hao Peng; Weixi Li; Tengjiao Li; Wuxia Guo; Yelin Huang (Biodiversity and Conservation, 2023)

Effect of Tyrosol Acyl Esters on the Antioxidant Status of Mussel ( Mytilus edulis ) Oil During Accelerated Oxidative Storage - Qian Wang; Mo-Tong Zhang; Xin-Miao Wang; Guan-Hua Zhao; Yuan-Yuan Hu; Fa-Wen Yin; Hui-Lin Liu; Xiao-Yang Liu; Da-Yong Zhou (Journal of Aquatic Food Product Technology, 2023)

A new chamigrane sesquiterpene from the rice fermentation of Antrodiella albocinnamomea - Min Guo; Ying-Zhong Liang; Xiu-Ming Cui; Lin-Jiao Shao; Yin-Fei Li; Xiao-Yan Yang (Natural Product Research, 2023)

Efficient and selective removal of Hg(II) from water using recyclable hierarchical MoS2/Fe3O4 nanocomposites - Shiyu Li; Lin Yang; Jialong Wu; Linlin Yao; Deming Han; Yong Liang; Yongguang Yin; Ligang Hu; Jianbo Shi; Guibin Jiang (Water Research, 2023)

Insight into the effect of pyrolysis temperature on photoreactivity of biochar-derived dissolved organic matter: Impacts of aromaticity and carbonyl groups - Hanzhuo Luo; Eydhah Almatrafi; Wenjun Wang; Yang Yang; Danlian Huang; Weiping Xiong; Min Cheng; Chengyun Zhou; Yin Zhou; Qing Lin; Guoge Fang; Guangming Zeng; et al. (Science of The Total Environment, 2023)

Virulence assessment of four Glaesserella parasuis strains isolated in Liaoning province of China - Ping Yan; Yong C. Jia; Xue L. Zhang; Yuan Y. Zhou; Ying Guo; Rong L. Yin; Jing Yuan; Lin X. Wang; Zhong B. Guo; Jing Y. Wang; Xin Wang; Rong H. Yin (Research in Veterinary Science, 2023)

5-epi-ent-Kaurane diterpenoids from the aerial parts of Isodon eriocalyx and their anti-atherosclerotic potential - Long Mu; Tian Li; Peng-Lin Wu; Ling-Qiao Cai; Shu-Ying Li; Zi-Yuan Wang; Yuan-Yuan Liu; Jie Wang; Dong Yan; Zheng-Yun Rao; Chao-Jun Wang; Jian Zhang; et al. (Phytochemistry, 2023)

Plate convergence controls long-term full-depth circulation of the South China Sea - Shaoru Yin; F. Javier Hernández-Molina; Lin Lin; Min He; Jinyao Gao; Jiabiao Li (Marine Geology, 2023)

Nitrogen-doped hydrochar prepared by biomass and nitrogen-containing wastewater for dye adsorption: Effect of nitrogen source in wastewater on the adsorption performance of hydrochar - Zhaohua Lin; Ruikun Wang; Shiteng Tan; Kai Zhang; Qianqian Yin; Zhenghui Zhao; Peng Gao (Journal of Environmental Management, 2023)

Coupling and decoupling of Au and As in pyrite from Carlin-type Au deposits, southwest China - Shiru Lin; Kai Hu; Jian Cao; Yin Liu; Shengjun Liu; Bin Zhang (Journal of Asian Earth Sciences, 2023)

Ultrafast microfluidic preparation of highly dispersed Ru/TiO2 catalyst for the hydrodeoxygenation of lignin-derived phenolic compounds - Zhuojie Zhong; Bowen Luo; Chengyin Lin; Tao Yin; Zhipeng Tian; Chao Wang; Ying Chen; Yanxue Wu; Riyang Shu (Fuel, 2023)

Effects of ultraviolet and infrared radiation absence or presence on the aroma volatile compounds in winegrape during veraison - Haining Yin; Lin Wang; Hanmei Su; Yanying Liang; Ping Ji; Xuefei Wang; Zhumei Xi (Food Research International, 2023)

Taurine reduces apoptosis mediated by endoplasmic reticulum stress in islet β-cells induced by high-fat and -glucose diets - Dongdong Zhao; Xiaozhou Zhang; Yongxin Bian; Lu Meng; Yutong Wu; Yidi Ma; Chen Li; Jingjing Wang; Zizheng Fu; Jingyuan Dai; Deqi Yin; Shumei Lin; et al. (Food and Chemical Toxicology, 2023)

Mechanisms of vegetation restoration at landslides caused by a catastrophic earthquake in Central Taiwan - Wen-Tzu Lin; Pi-Hui Huang; Tien-Yin Chou (Ecological Engineering, 2023)

The shadows hang over immunotherapy-neutrophil extracellular traps in cancer - Dan Pu; Liyuan Yin; Xiaoqian Zhai; Ruoxiang Wang; Lin Huang; Qiang Wu; Lingling Zhu; Yuwen Zhou; Qinghua Zhou; Lu Li (Science China Life Sciences, 2023)

Dissolved black carbon concentrations in suspended particulate matter from the Bohai Sea - Chongtai Chen; Yin Fang; Yingjun Chen; Tian Lin; Fengchang Wu (Science China Earth Sciences, 2023)

Quercetin alleviates tubulointerstitial inflammation by inhibiting exosomes-mediated crosstalk between tubular epithelial cells and macrophages - Di Yin; Jing-Yuan Cao; Yan Yang; Zhong-Tang Li; Hong Liu; Tao-Tao Tang; Wei-Jie Ni; Yi-Lin Zhang; Wei Jiang; Yi Wen; Zuo-Lin Li; Jing Zhao; et al. (Inflammation Research, 2023)

Adaption of tobacco rattle virus to its solanaceous hosts is related to the codon usage bias of the hosts and that of the viral 16 K gene - Qi Lin; Yuanting Zheng; Yueyan Yin; Yi Chen; Miaomiao Li; Hongying Zheng; Jianping Chen; Fei Yan; Yuwen Lu; Shengchun Xu (European Journal of Plant Pathology, 2023)

A concise synthesis of marine natural product (−)-15-oxopuupehenol from (+)-sclarelide - Yun-Fei Cheng; Hui-Jing Li; Yin-Lin Zhang; Yan-Chao Wu (Natural Product Research, 2023)

Extended chloramination significantly enriched intracellular antibiotic resistance genes in drinking water treatment plants - Haibei Li; Hongling Yu; Yongbing Liang; Xudong Zhang; Dong Yang; Lin Wang; Danyang Shi; Tianjiao Chen; Shuqing Zhou; Jing Yin; Zhongwei Yang; Junwen Li; et al. (Water Research, 2023)

Activated AMPK-mediated glucose uptake and mitochondrial dysfunction is critically involved in the glutamate-induced oxidative injury in HT22 cell - Shao-Peng Lin; Jingyi Bu; Shan Ye; Qiangda Xie; Jue-Xian Wei; Xiaofang Yin; Fen Mei; Pei-Yi Lin; Xiao-Hui Chen (Tissue and Cell, 2023)

The ginsenoside Rh2 protects porcine oocytes against aging and oxidative stress by regulating SIRT1 expression and mitochondrial activity - Hongye Liu; Zhi-Yong An; Zhou-Yan Li; Liu-Hui Yang; Xiu-Li Zhang; Yan-Tong Lv; Xi-Jun Yin; Lin-Hu Quan; Jin-Dan Kang (Theriogenology, 2023)

Dynamic damage characteristics of mudstone around hammer driven pile and evaluation of pile bearing capacity - Jichao Yin; Xiaoyu Bai; Nan Yan; Songkui Sang; Lin Cui; Junwei Liu; Mingyi Zhang (Soil Dynamics and Earthquake Engineering, 2023)

Responses of microbial community to geochemical parameters on vertical depth in bioheap system of low-grade copper sulfide - Xiu-Tong Li; Zhong-Sheng Huang; Ye Huang; Zhen Jiang; Zong-Lin Liang; Hua-Qun Yin; Guang-Ji Zhang; Yan Jia; Ye Deng; Shuang-Jiang Liu; Cheng-Ying Jiang (Science of The Total Environment, 2023)

Chronic environmental inorganic arsenic exposure causes social behavioral changes in juvenile zebrafish (Danio rerio) - Yi-Hong Wang; Ya-Qian Wang; Xiao-Gang Yu; Yin Lin; Jun-Xia Liu; Wei-Ye Wang; Chong-Huai Yan (Science of The Total Environment, 2023)

Late Tonian (ca. 785 Ma) subduction-related mafic-ultramafic cumulates in the West Cathaysia terrane, South China - Lijun Wang; Kexin Zhang; Shoufa Lin; Jean H. Bédard; Gabriel S. Santos; Weihong He; Changqing Yin; Wenjiao Xiao (Precambrian Research, 2023)

Nano-Fe3O4 coated on carbon monolith for anode enhancement in microbial fuel cells - Yini Chen; Fan Zhao; Yu Pu; Xiangyu Lin; Haoran Yin; Xinhua Tang (Journal of Environmental Chemical Engineering, 2023)

The contribution of subliminal perceptions, dietary habits, and psychological traits to the perception of oral tingling and burning sensations - Lu-lu Zhang; Chao Ma; Hou-yin Wang; Ying-ming Zheng; Qing-bin Zhang; Kui Zhong; Bo-lin Shi; Lei Zhao (Food Research International, 2023)

Effect of ferulic acid covalent conjugation on the functional properties and antigenicity of β-lactoglobulin - Yu-Ting Xue; Ya-Ning Han; Yan Wang; Ying-Hua Zhang; Yu-Qi Yin; Bo-Hao Liu; Han-Lin Zhang; Xin-Huai Zhao (Food Chemistry, 2023)

Polystyrene microplastics arrest skeletal growth in puberty through accelerating osteoblast senescence - Chun Pan; Yin Wu; Sihan Hu; Ke Li; Xiangyu Liu; Yu Shi; Wenzheng Lin; Xinglong Wang; Yujie Shi; Zhuobin Xu; Huihui Wang; Hao Chen (Environmental Pollution, 2023)

Valorization of lignin through reductive catalytic fractionation of fermented corn stover residues - Wen-Zheng Yin; Ling-Ping Xiao; Shuang-Lin Zou; Wen-Xin Li; Hongliang Wang; Run-Cang Sun (Bioresource Technology, 2023)

Quantitative characterization of filamentous fungal promoters on a single-cell resolution to discover cryptic natural products - Peng-Lin Wei; Jie Fan; Jingwen Yu; Zihui Ma; Xian Guo; Nancy P. Keller; Erwei Li; Chunbo Lou; Wen-Bing Yin (Science China Life Sciences, 2023)

The evolution and determinants of Chinese inter-provincial green development efficiency: an MCSE-DEA-Tobit-based perspective - Lin Yang; Zhanxin Ma; Jie Yin; Yiming Li; Haodong Lv (Environmental Science and Pollution Research, 2023)

Pharmacokinetics and residue elimination of metalaxyl enantiomers in snakehead (Channa argus) - Hao Zhou; Meiyu Zhang; Qi Shan; Heqing Huang; Meiling Zhang; Shugui Liu; Jiawei Lin; Lisha Ma; Guangming Zheng; Lichun Li; Cheng Zhao; Xiaoxin Dai; et al. (Aquaculture, 2023)

Reactive and microbial inhibitory mechanisms depicting the panoramic view of pH stress effect on common biological nitrification - Xuehai Yue; Hong Liu; Haotian Wei; Lin Chang; Zhengjun Gong; Lei Zheng; Fengjun Yin (Water Research, 2023)

Corrigendum to “Induction of core symptoms of autism spectrum disorders by in vivo CRISPR/Cas9-based gene editing in the brain of adolescent rhesus monkeys” [Sci. Bull. 66(9) (2021) 937–946] - Shi-Hao Wu; Xiao Li; Dong-Dong Qin; Lin-Heng Zhang; Tian-Lin Cheng; Zhi-Fang Chen; Bin-Bin Nie; Xiao-Feng Ren; Jing Wu; Wen-Chao Wang; Ying-Zhou Hu; Yi-lin Gu; et al. (Science Bulletin, 2023)

Diverse alkaloids from the aerial parts of Aconitum carmichaelii and antiproliferative activity of costemline via inhibiting SIRT1/ROCK1/P-STAT3 pathways - Yin-Lin Zhou; Duan-Na Zhang; Ji-Xu Qiao; Jing Wu; Yong-Ming Yan; Zhi-Xing Cao; Cheng Peng; Yu-Zhu Tan (Phytochemistry, 2023)

Ca2+-dependent TaCCD1 cooperates with TaSAUR215 to enhance plasma membrane H+-ATPase activity and alkali stress tolerance by inhibiting PP2C-mediated dephosphorylation of TaHA2 in wheat - Minghan Cui; Yanping Li; Jianhang Li; Fengxiang Yin; Xiangyu Chen; Lumin Qin; Lin Wei; Guangmin Xia; Shuwei Liu (Molecular Plant, 2023)

Remediation performance and mechanisms of Cu and Cd contaminated water and soil using Mn/Al-layered double oxide-loaded biochar - Pengcheng Lin; Hang Liu; Hua Yin; Minghan Zhu; Haoyu Luo; Zhi Dang (Journal of Environmental Sciences, 2023)

Infant food production environments: A potential reservoir for vancomycin-resistant enterococci non-nosocomial infections - Zining Wang; Sihao Liao; Guanwen Huang; Mengyao Feng; Rui Yin; Lin Teng; Chenghao Jia; Yicheng Yao; Min Yue; Yan Li (International Journal of Food Microbiology, 2023)

A 13 million-year record of Li isotope compositions in island carbonates: Constraints on bulk inorganic carbonate as a global seawater Li isotope archive - Guang-Yi Wei; Feifei Zhang; Yi-Sheng Yin; Yi-Bo Lin; Philip A.E. Pogge von Strandmann; Mengchun Cao; Na Li; Guolin Xiong; Xinran Chen; Caiwei Fan; Changgui Xu; Fei Tan; et al. (Geochimica et Cosmochimica Acta, 2023)

Comparative investigation on the pyrolysis of crop, woody, and herbaceous biomass: Pyrolytic products, structural characteristics, and CO2 gasification - Lin Mu; Ranyu Wang; Pengwei Xie; Yonglin Li; Xiankun Huang; Hongchao Yin; Ming Dong (Fuel, 2023)

A highly sensitive electrochemical immunosensor based on electrospun nanocomposite for the detection of parathion - Wen-jia Yin; Jing-xian Zhang; Hong Wang; Yu Wang; Xi Zeng; Zhen-lin Xu; Jin-yi Yang; Zhi-li Xiao; Bruce D. Hammock; Peng Wen (Food Chemistry, 2023)

Locking-DNA network regulated CRISPR-Cas12a fluorescent aptasensor based on hollow flower-like magnetic MoS2 microspheres for sensitive detection of sulfadimethoxine - Yan Lv; Yuhan Sun; Imran Mahmood Khan; Qiaofeng Li; You Zhou; Lin Yue; Yin Zhang; Zhouping Wang (Chemical Engineering Journal, 2023)

Corrigendum to “Discovery and characterization of the flavonoids in Cortex Mori Radicis as naturally occurring inhibitors against intestinal nitroreductases” [Chem. Biol. Interact. 368 (2022) 110222] - Xi Chen; Yue Han; Lu Chen; Qian-Lin Tian; Yu-Ling Yin; Qi Zhou; Shi-Zhu Zang; Jie Hou (Chemico-Biological Interactions, 2023)

Response characteristics of antibiotic resistance genes and bacterial communities during agricultural waste composting: Focusing on biogas residue combined with biochar amendments - Yuewei He; Xiaowei Yin; Fanghong Li; Bo Wu; Ling Zhu; Dabing Ge; Nanyi Wang; Anwei Chen; Lihua Zhang; Binghua Yan; Hongli Huang; Lin Luo; et al. (Bioresource Technology, 2023)

Sex difference on fibroblast growth factors (FGFs) expression in skin and wound of streptozotocin(STZ)-induced type 1 diabetic mice - Nuo-qi Wang; Wei-hua Jia; Lin Yin; Na Li; Mei-dai Liang; Jia-min Shang; Bi-yu Hou; Li Zhang; Gui-fen Qiang; Guan-hua Du; Xiu-ying Yang (Molecular Biology Reports, 2023)

Exposure to Endocrine-Disrupting Chemicals and Type 2 Diabetes Mellitus in Later Life - Jian-Yan Lin; Rui-Xing Yin (Exposure and Health, 2023)
Type 2 diabetes mellitus (T2DM), one of the most common chronic metabolic diseases, involves a complex interaction among genetic, epigenetic, and environmental risk factors. The incidence and prevalence of T2DM are rapidly increasing globally. In recent years, increasing body of evidences from both human and animal studies have displayed an association between exposure to early unfavorable life factors such as endocrine-disrupting chemicals (EDCs) and the prevalence of T2DM in later life. The exogenous EDCs can lead to disadvantageous metabolic consequences because they interfere with the synthesis, secretion, transport, binding, action, and metabolism of endogenous hormones. EDCs also have long-term adverse effects on newborns, children, and adolescents by causing increased susceptibility to T2DM in adults. This review summarizes the most recent advances in this field, including diabetes-related EDCs (bisphenol A, phthalates, chlordane compounds, parabens, pesticides, and other diabetes-related EDCs), EDC exposure and gestational diabetes mellitus, prenatal and perinatal EDC exposures and T2DM, adult EDC exposure and T2DM, transgenerational effects of EDCs on T2DM as well as the possible diabetogenic mechanisms.

Application of improved support vector machine in geochemical lithology identification - Shitao Yin; Xiaochun Lin; Yongjian Huang; Zhifeng Zhang; Xiang Li (Earth Science Informatics, 2023)

The Tick-Borne Pathogens: An Overview of China’s Situation - Yuxuan Luan; Jingmin Gou; Dongjie Zhong; Li Ma; Chuansong Yin; Minfeng Shu; Guangyuan Liu; Qing Lin (Acta Parasitologica, 2023)

Genome-wide association study reveals markers and candidate genes associated with growth in the rice flower carp, an economic fish species of integrated rice-fish culture in China - Hui Luo; Xianhui Pan; Yin Huang; Zhe Li; Hua Ye; Kangqi Zhou; Luting Wen; Junqi Qin; Wenping He; Xuesong Du; Dapeng Wang; Yong Lin (Frontiers in Marine Science, 2023)
The rice flower carp ( Cyprinus carpio ) is an important fish in integrated rice-fishery farming. Here, we performed the first genome-wide association study (GWAS) for seven growth traits (including body mass, total length, body length, body height, body width, caudal-peduncle depth, and eye spacing) in 200 rice flower carp samples using 369,688 high-quality SNPs and 42,225 indels obtained by double-digest genotyping-by-sequencing (ddGBS). The morphometrics of these traits were highly correlated (Pearson’s correlation coefficients = 0.74–0.99, p < 0.001). GWAS detected 15, 5, 4, 26, 7, 16, and 17 loci significant associated (-log10P ≥ 5) with body mass, total length, body length, body width, body height, caudal-peduncle depth, and eye spacing, respectively. Subsequently, within the 50 kb upstream and downstream regions surrounding these significant loci, 38, 19, 18, 20, 52, 27, and 37 candidate genes for the seven growth traits were detected, respectively. Importantly, B6_4352672 and A8_4978825 were significantly associated with more than five growth traits. These results showed loci significantly associated with more than five growth traits will be helpful for future marker-assisted selection (MAS). Interestingly, chromosomes A8 and B25 had many loci significantly associated with growth traits, most of which were shared among multiple growth-related traits. These results indicated that chromosome A8 and B25 may be closely related to growth traits. Our findings not only help understand the genetic architecture of growth traits in fish but facilitate the identification of candidate genes for marker-assisted selection towards breeding faster-growing rice flower carp in the future.

Effects of periodic drying-wetting on microbial dynamics and activity of nitrite/nitrate-dependent anaerobic methane oxidizers in intertidal wetland sediments - Feiyang Chen; Yuhui Niu; Zhirui An; Li Wu; Jie Zhou; Lin Qi; Guoyu Yin; Hongpo Dong; Xiaofei Li; Dengzhou Gao; Min Liu; Yanling Zheng; et al. (Water Research, 2023)

Rural-urban disparities in the associations of residential greenness with diabetes and prediabetes among adults in southeastern China - Wanqi Yu; Xiaoqing Li; Wenling Zhong; Shu Dong; Chuanteng Feng; Bin Yu; Xi Lin; Yanrong Yin; Tiehui Chen; Shujuan Yang; Peng Jia (Science of The Total Environment, 2023)

Divergent responses and ecological risks of wheat (Triticum aestivum L.) to cerium oxide nanoparticles in different soil types - Dun Chen; Zihan Lin; Fuxun Ai; Yan Xia; Wenchao Du; Ying Yin; Hongyan Guo (Science of The Total Environment, 2023)

Triclocarban and triclosan exacerbate high-fat diet-induced hepatic lipid accumulation at environmental related levels: The potential roles of estrogen-related receptors pathways - Xin Li; Jia-Da Zhang; Han Xiao; Sen He; Ting-Ting He; Xiao-Min Ren; Bing-Hua Yan; Lin Luo; Yu-Long Yin; Lin-Ying Cao (Science of The Total Environment, 2023)

Between the devil and the deep blue sea: Trends, drivers, and impacts of coastal reclamation in Malaysia and way forward - Su Yin Chee; Mou Leong Tan; Yi Lin Tew; Yee Kwang Sim; Jean Chai Yee; Amanda Kar Mun Chong (Science of The Total Environment, 2023)

Marine environmental monitoring with unmanned vehicle platforms: Present applications and future prospects - Shuyun Yuan; Ying Li; Fangwen Bao; Haoxiang Xu; Yuping Yang; Qiushi Yan; Shuqiao Zhong; Haoyang Yin; Jiajun Xu; Ziwei Huang; Jian Lin (Science of The Total Environment, 2023)

Quantitative analysis of the structural evolution in Si anode via multi-scale image reconstruction - Chen Zhu; Shiming Chen; Ke Li; Zu-Wei Yin; Yinguo Xiao; Hai Lin; Feng Pan; Luyi Yang (Science Bulletin, 2023)

Two new pentasaccharide resin glycosides from Argyreia acuta - Yi-Lin Niu; Zhi-Tong Li; Yong-Qin Yin (Phytochemistry Letters, 2023)

Assessment of future socioeconomic drought based on CMIP6: evolution, driving factors and propagation - Tian Wang; Xinjun Tu; Vijay P. Singh; Xiaohong Chen; Kairong Lin; Zonglin Zhou; Yin Tan (Journal of Hydrology, 2023)

Emission, partition, and formation pathway of polychlorinated dibenzo-p-dioxins and dibenzofurans during co-disposal of industrial waste with municipal solid waste - Yuxuan Ying; Yunfeng Ma; Xiaoxiao Wang; Hong Yu; Angjian Wu; Shengyong Lu; Xiaodong Li; Xiaoqing Lin; Lijun Liu; Wenhua Yin (Journal of Environmental Chemical Engineering, 2023)

New insight into the combined effects of ibuprofen and Cu (II) on activated sludge system: System performance, community structure, microbial interaction network - Daying Chen; Minglu Zhang; Yanwen Qin; Zhimin Wang; Meilin Yin; Minghan Zhu; Lin Zhao; Xiaohui Wang (Journal of Environmental Chemical Engineering, 2023)

The effects of light, conspecific density and soil fungi on seedling growth of temperate tree species - Jin Yin; Fei Lin; Emiel De Lombaerde; Zikun Mao; Shufang Liu; Ji Ye; Shuai Fang; Xugao Wang (Forest Ecology and Management, 2023)

Comprehensive application possibility: Construction hydrophilic, amphiphilic and hydrophobic system of modified zein by enzymatic or cysteine modification - An-Qi Zhang; Xiao-Yan Li; Bo-Hao Liu; Yu-Qi Yin; Han-Lin Zhang; Ying-Hua Zhang (Food Hydrocolloids, 2023)

Effect of Paecilomyces cicadae polysaccharide Pc0-1 on cyclophosphamide-induced immunosuppression and regulation of intestinal flora in mice - Shiwei Yao; Xingwen Yang; Weijie Wu; Qihong Jiang; Shanggui Deng; Bin Zheng; Lin Chen; Yin Chen; Xingwei Xiang (Food Bioscience, 2023)

Hyperoside attenuates Cd-induced kidney injury via inhibiting NLRP3 inflammasome activation and ROS/MAPK/NF-κB signaling pathway in vivo and in vitro - Ziyin Li; Weizuo Liao; Xinxin Yin; Lili Liu; Zhiqiang Zhao; Xiaodan Lu; Feifei Xu; Xiuqin Lin; Yingsi Chen; Jia Song; Zhini He; Qinzhi Wei; et al. (Food and Chemical Toxicology, 2023)

Catalytic activity enhancement by P and S co-doping of a single-atom Fe catalyst for peroxymonosulfate-based oxidation - Yin Li; Jiahui Hu; Yubin Zou; Lin Lin; Hebin Liang; Huaxin Lei; Bing Li; Xiao-yan Li (Chemical Engineering Journal, 2023)

Sulfur isotope, fluid inclusions, and quartz solubility model decipher multistage hydrothermal fluids evolution and ore precipitation mechanism at the Nantai porphyry Mo deposit, Qinling, Central China - Zhong-Yu Zhang; Yin-Hong Wang; Jia-Jun Liu; Shan-Yuan Lin; Fang-Fang Zhang; Wei Zhang; Zhen-Yu Bo; Hui Zhang; Hong-Yu Li (Chemical Geology, 2023)

Cholesterol homeostasis regulated by ABCA1 is critical for retinal ganglion cell survival - Jialiang Yang; Yuhong Chen; Tongdan Zou; Bai Xue; Fang Yang; Xiangzhou Wang; Yibo Huo; Boyun Yan; Yuxia Xu; Shiyu He; Yi Yin; Jing Wang; et al. (Science China Life Sciences, 2023)

Human platelet mitochondria improve the mitochondrial and cardiac function of donor heart - Zhi Jun Lin; Soomin Kim; Hui Xing Cui; Kyuboem Han; Hong Kyu Lee; Chun-Hyung Kim; Young Cheol Kang; Yin Hua Zhang (Pflügers Archiv - European Journal of Physiology, 2023)

PROK2–PROKR2 Signaling: New Contributor to Pleasant Touch - Feng-Lin Chen; Hai-Yan Yin; Yong Tang (Neuroscience Bulletin, 2023)

In situ phytostabilization of arable soils severely contaminated with cadmium at Yangshuo, Southern China, using cash crops and amendments: a comprehensive performance evaluation - Bo-Fang Yan; Mei-Lin Yan; Xue Xiao; Rong-Liang Qiu; Yuan-Qing Chao; Yin-Xin Li; Su-Lian Lv; Zhong-Xin Tan; Ye-Tao Tang (Journal of Soils and Sediments, 2023)

Orbital and Millennial-Scale Climate Variability over the Past 76 ka in the Western Tarim Basin, Northwest China - Rui Zhang; Qiuzhen Yin; Weihua Nai; Zhixiang Wang; Hao Lu; Chunju Huang; Yansheng Gu; Lin Li; Yusong Wang; Linjing Liu (Journal of Earth Science, 2023)

Seasonal spermatogenesis, epididymal storage, and creatine kinase expression in Pelodiscus sinensis - Yu-Fei Yang; Jia-Hao Wu; Run-Lan Lin; Shang-Jun Yin; Guo-Ying Qian; Wei Wang; Yong-Doo Park (Animal Reproduction Science, 2023)

Effective immobilization of Cd(II) in soil by biotic zero-valent iron and coexisting sulfate - Weiquan Li; Yuhang Yang; Xueying Lin; Weizhao Yin; Zhanqiang Fang; Ping Li; Jinhua Wu (Chemosphere, 2023)

Ambient air pollution, bone mineral density and osteoporosis: Results from a national population-based cohort study - Yin Yang; Rui Li; Miao Cai; Xiaojie Wang; Haopeng Li; Yinglin Wu; Lan Chen; Hongtao Zou; Zilong Zhang; Haitao Li; Hualiang Lin (Chemosphere, 2023)

The hybrid Pelteobagrus fulvidraco (♀) × Leiocassis longirostris (♂) exhibits improved trait on hypoxia-tolerance - Hongyu Wang; Ge Lin; Jie Zhou; Yongqin Zong; Xianhui Ning; Tao Wang; Shaowu Yin; Kai Zhang; Jie Ji (Aquaculture, 2023)

Impact of synoptic condition on urban microclimate variation: A measurement study in a humid subtropical city during summer season - Shi Yin; Junyi Hua; Chao Ren; Sheng Liu; Hankun Lin; Songyi Huang; Kun Wang; Jiaxing Ma; Yiqiang Xiao (Urban Climate, 2023)

Transcriptomics and metabolomics together reveal the underlying mechanism of heroin hepatotoxicity - Yingbiao Yue; Lei Zou; Jie Tao; Lin Yin; Zhenrong Xie; Yu Xia; Zunyue Zhang; Kunhua Wang; Mei Zhu (Toxicology, 2023)

Corrigendum to Correlation among the Ailaoshan-Song Ma-Song Chay orogenic belts and implications for the evolution of the eastern Paleo-Tethys Ocean [Tectonophysics 843 (2022) 229618]. - Yin Wang; Wei Lin; Michel Faure; Vuong Van Nguyen; Lingtong Meng; Yang Chu; Wei Wei; Hoai Luong Thi Thu; Claude Lepvrier; Tich Van Vu; Qiuli Li; Hao Wang; et al. (Tectonophysics, 2023)

Study on damage constitutive relationship of mudstone affected by dynamic pile driving - Yamei Zhang; Jichao Yin; Xiaoyu Bai; Lin Cui; Songkui Sang; Junwei Liu; Nan Yan; Mingyi Zhang (Soil Dynamics and Earthquake Engineering, 2023)

Assessment of factors affecting the diurnal variations of atmospheric PAHs based on a numerical simulation - Zhongxiu Zhen; Yan Yin; Haowen Zhang; Jingyi Li; Jianlin Hu; Lin Li; Xiang Kuang; Kui Chen; Honglei Wang; Qingyuan Yu; Xin Zhang (Science of The Total Environment, 2023)

Zero-valent iron boosts nitrate-to-ammonia bioconversion via extracellular electron donation and reduction pathway complementation - Xue Li; Jie Li; Xiao-Rong Yu; Yong-Kun Zhu; Hou-Qi Liu; Lin Chen; Jing Wu; Xian-Zhong Fu; Shuo Cui; Tian-Yin Huang; Ru-Quan Ye; Wen-Wei Li (Resources, Conservation and Recycling, 2023)

Competitive control of multiscale aquifer heterogeneity on solute transport in an alluvial aquifer - Maosheng Yin; Rui Ma; Yong Zhang; Jingjing Lin; Zhilin Guo; Chunmiao Zheng (Journal of Hydrology, 2023)

New insights into lincomycin biodegradation by Conexibacter sp. LD01: Genomics characterization, biodegradation kinetics and pathways - Huaxin Lei; Jiayu Zhang; Jin Huang; Dengjin Shen; Yin Li; Rui Jiao; Renxin Zhao; Xiaoyan Li; Lin Lin; Bing Li (Journal of Hazardous Materials, 2023)

A carbon-neutral scenario simulation of an urban land–energy–water coupling system: A case study of Shenzhen, China - Gang Lin; Dong Jiang; Yitong Yin; Jingying Fu (Journal of Cleaner Production, 2023)

Effects of dietary Ginkgo biloba leaf extract on growth performance, immunity and environmental stress tolerance of Penaeus vannamei - Meiqiu Liao; Feifei Wang; Lin Huang; Can Liu; Wenna Dong; Xueqi Zhuang; Xiaoli Yin; Yuan Liu; Weina Wang (Fish & Shellfish Immunology, 2023)

Residential greenness and dyslipidemia risk: Dose-response relations and mediation through BMI and air pollution - Qinjian Wang; Xiaoqing Li; Wenling Zhong; Hongyun Liu; Chuanteng Feng; Chao Song; Bin Yu; Yao Fu; Xi Lin; Yanrong Yin; Tiehui Chen; Jan D. Reinhardt; et al. (Environmental Research, 2023)

Inorganic sulfur cycles in sediments of the Pearl River Estuary: Processes, mechanisms, and isotopic indicators - Xijie Yin; Yunpeng Lin; Yunhai Li; Liang Wang; Zhilei Sun; Guogang Li (Estuarine, Coastal and Shelf Science, 2023)

Bisphenol A exacerbates selenium deficiency-induced pyroptosis via the NF-κB/NLRP3/Caspase-1 pathway in chicken trachea - Kexin Yin; Xinyue Sun; Yaxin Zheng; Wenyue Zhang; Hongjin Lin (Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2023)

Adjusting charge kinetics of conjugated polymers via integration of LSPR effect with homojunction - Mingjuan Zhang; Lin Tang; Abing Duan; Yi Zhang; Fengjiao Xiao; Yuan Zhu; Jiajia Wang; Chengyang Feng; Nian Yin (Chemical Engineering Journal, 2023)

Clustered regularly interspaced short palindromic repeats (CRISPR) technology and genetic engineering strategies for microalgae towards carbon neutrality: A critical review - Tse-Min Lee; Jia-Yi Lin; Tsung-Han Tsai; Ru-Yin Yang; I-Son Ng (Bioresource Technology, 2023)

Carotenoid components and their biosynthesis in a bud mutant of Shiranui mandarin (Citrus reticulata Blanco) with citrine flavedo - Xun Wang; Jinqiu Huang; Zongyan Yin; Ke Xu; Dong Jiang; Lijin Lin; Xiaoai Zhang; Zhihui Wang (Journal of Zhejiang University-SCIENCE B, 2023)

Experimental investigation on spontaneous combustion oxidation characteristics and stages of coal with different metamorphic degrees - Baisheng Nie; Hongwei Yan; Peijun Liu; Zongyu Chen; Chao Peng; Xiaotong Wang; Feifei Yin; Jie Gong; Yueying Wei; Shuangshuang Lin; Qiang Gao; Mingwei Cao (Environmental Science and Pollution Research, 2023)

Spatio-temporal association mining of intercity PM2.5 pollution: Hubei Province in China as an example - Jiangping Chen; Xiaofeng Song; Lin Zang; Feiyue Mao; Jianhua Yin; Yi Zhang (Environmental Science and Pollution Research, 2023)

Multi-Degree-of-Freedom for Underwater Optical Wireless Communication with Improved Transmission Performance - Anliang Liu; Ruolin Zhang; Bin Lin; Hongxi Yin (Journal of Marine Science and Engineering, 2022)
Underwater optical wireless communication (UOWC) has great potential to provide high-speed and intensive communications over short ranges underwater. However, the mobility of the UOWC system is limited by the strict alignment requirements between the transceivers. In this paper, a multi-degree-of-freedom (MDOF) UOWC system with high flexibility and improved transmission performance is proposed and experimentally demonstrated based on the off-the-shelf light-emitting diode (LED) source. A hardware pre-equalization circuit is employed at the transmitter to extend the modulation bandwidth from 5.03 MHz to 50 MHz. At the receiving end, a Fresnel lens array is constructed to achieve efficient convergence of multiple incident optical signals from different directions. To improve the underwater signal transmission quality, we designed an additional digital signal recovery module after the trans-impedance amplifier. Finally, an experimental system is established with a 460 nm blue LED. The communication reliability of the system is verified by the measurement of the eye diagram and the bit error rate of the recovered signal at the receiving end. The experimental results show that optical signals from three different incident directions with a maximum data rate of 100 Mbps are reliably transmitted over a 1.2-m-long water tank using the non-return-to-zero on-off-keying modulation format.

The effects of extracellular algicidal compounds of Bacillus sp. B1 on Heterosigma akashiwo: a metabolomics approach - Xuanyue Li; Zehong Lin; Meiyi Yuan; Ling Zhao; Pinghe Yin (Environmental Science and Pollution Research, 2022)

Research status, challenges and future prospects of renewable synthetic fuel catalysts for CO2 photocatalytic reduction conversion - Yujun Chen; Bin Guan; Xingze Wu; Jiangfeng Guo; Zeren Ma; Jinhe Zhang; Xing Jiang; Shibo Bao; Yiyan Cao; Chengdong Yin; Di Ai; Yuxuan Chen; et al. (Environmental Science and Pollution Research, 2022)

Physio-Biochemical and Transcriptional Responses to Heat Stress in Seedlings Following Carbon Ion Beam Irradiation of Arabidopsis Seeds - Lin Wang; Ruonan Ma; Yue Yin; Zhen Jiao (Journal of Plant Growth Regulation, 2022)

Correction to: MiR‑30c‑1‑3p targets matrix metalloproteinase 9 involved in the rupture of abdominal aortic aneurysms - Lin Yang; Hong‑Gang Sui; Meng‑Meng Wang; Jia‑Yin Li; Xiao‑Feng He; Jing‑Yuan Li; Xiao‑Zeng Wang (Journal of Molecular Medicine, 2022)

Identification of the Hub Genes and the Signaling Pathways in Human iPSC-Cardiomyocytes Infected by SARS-CoV-2 - Li-Min Xie; Yin-Fei Huang; Ye-Ling Liu; Jia-Qi Liang; Wei Deng; Geng-Ling Lin; Huan-Min Luo; Xu-Guang Guo (Biochemical Genetics, 2022)

Study on the chemical composition of Caesalpinia sinensis - Lu-Fen Leng; Qi Lai; Dian Lv; Jun-Lin Yin; Guang-Zhi Zeng (Natural Product Research, 2022)

Does isolated nuchal translucency from 2.5 to 2.9 mm increase the risk of fetal chromosome disease? - Daishu Yin; Lin Chen; Li Wang; Yang Zeng; Feng Tang; Jing Wang (Molecular Genetics and Genomics, 2022)

Multi-stage melt impregnation and magma–seawater interaction in a slow-spreading oceanic lithosphere: constraints from cumulates in the Lagkorco ophiolite (central Tibet) - Wei-Qi Zhang; Chuan-Zhou Liu; Tong Liu; Chang Zhang; Zhen-Yu Zhang; Xiao-Ni Li; Zhen Zhang; Yin-Zheng Lin (Contributions to Mineralogy and Petrology, 2022)

Complete genome sequence of iris potyvirus B infecting Lilium lancifolium in China - Qi Lin; Dankan Yan; Mengying Hua; Yueyan Yin; Hongying Zheng; Jianping Chen; Fei Yan; Jiejun Peng; Qiongji He; Yuwen Lu (Archives of Virology, 2022)

Rare earth element characteristics of the Permian Lucaogou Formation shale in the Junggar Basin, Northwest China - Jun Yin; Li Wang; Haitao Lin; Yali Zhu (Arabian Journal of Geosciences, 2022)

Xenoestrogen Status of Wuling Farm to Surrounding Water Bodies: An Application of Biochemical Parameters Using Onychostoma barbatulum - Lin-Yan Liao; Hui-Ling Cheng; Shu-Yin Wang; Shih-Hsiung Liang; Da-Ji Huang (Journal of Marine Science and Engineering, 2022)
The aim of this study was to apply biochemical parameters to Onychostoma barbatulum to understand whether Wuling Farm activities have caused organic pollution from xenoestrogens to flow into surrounding streams and thereby affected area aquatic ecosystems. Individuals of the Taiwan shovel-jaw carp (O. barbatulum) were collected by fyke netting in the Cijiawan, Kaoshan, and Yusheng Rivers in the protected area of Shei-Pa National Park and in the Ikawan River outside the protected areas from 4–5 June 2015 to 20–21 September 2015. The collected male individuals of O. barbatulum were divided into two groups. In the first group monooxygenase (Mon) activity, glutathione S-transferase (GST) activity, and vitellogenin (VTG) concentration in the liver were measured right after they were captured. Those in the second group were acclimated for 14 days and then exposed to 0 (control) or 10 ng/L 17β-estradiol for 10 days and then measured for changes in Mon, GST, and VTG in their livers. The value of VTG concentrations in O. barbatulum individuals collected from the Ikawan River was 2.12 ± 1.62 μg PO42+/g protein, which was the highest among all samples, followed by those collected from the Yusheng River (0.78 ± 1.00 μg PO42+/g protein). Individuals collected from the Yusheng River had the highest liver Mon activity (4.16 ± 1.08△A650/30 min/g protein) and the highest GST activity (1.58 ± 1.13 △A340/20 min/g protein), followed by those from the Ikawan River (Mon: 3.63 ± 1.13 △A650/30 min/g protein; GST: 1.24 ± 0.73 △A340/20 min/g protein). Comprehensive analyses showed that Mon and GST activities and VTG concentrations in livers measured right after being collected were lower than individuals exposed to 10 ng 17β-estradiol/L in the laboratory. Induced VTG concentrations were 9.87 ± 0.89 μg PO42+/g protein, Mon activity 8.02 ± 1.74 △A650/30 min/g protein, and GST activity 3.24 ± 0.62 △A340/20 min/g protein, indicating that farming activities have not significantly affected these aquatic organisms. However, pollution sources are still releasing pollutants containing xenoestrogens into the Yusheng River and Ikawan River. The impact of xenoestrogens is worthy of continuous long-term follow-up monitoring.

Establishment and characterization of a spinal cord tissue cell line from mandarin fish, Siniperca chuatsi and its susceptibility to several viruses - Jinpeng Gong; Xiaoyi Pan; Lingyun Lin; Yue Zhu; Jiayun Yao; Congxu Wang; Wenlin Yin; Lei Huang; Yihan Liu; Fan Chen; Jinyu Shen (Journal of Fish Diseases, 2022)
In this study, we established and characterized a continuous cell line from the spinal cord tissue of mandarin fish, Siniperca chuatsi and assessed its susceptibility to infectious spleen and kidney necrosis virus (ISKNV), Siniperca chuatsi ranavirus (SCRaV) and Siniperca chuatsi rhabdovirus (SCRV). The cell line, named SCC, has been successively cultured up to 40 passages. The optimal growing conditions of SCC cells were in Leibovitz's L‐15 medium supplemented with 20% foetal bovine serum (FBS) at 28°C. Karyotype analysis demonstrated 48 normal diploid chromosomes in the cells. The identity of S. chuatsi origin of SCC cells was confirmed by partial sequencing of the 16S rRNA and cytochrome oxidase I ( COI ) genes. Infection susceptibility assessment showed that ISKNV, SCRIV and SCRV and can be stably produced and transmitted in SCC cells, and the replication efficiency of ISKNV, SCRaV and SCRV ranged from 10 7.4 to 10 9.6 TCID 50 /ml. In addition, transmission electron microscopy analysis of ISKNV, SCRAV and SCRV infected SCC cells showed numerous viral particles. In conclusion, the newly established SCC cells provide an important tool for isolation and production of viruses, as well as for molecular and cell biology studies.

Endothelial cells induce degradation of ECM through enhanced secretion of MMP14 carried on extracellular vesicles in venous malformation - Gao-Hong Chen; Jie-Gang Yang; Hou-Fu Xia; Lin-Zhou Zhang; Yin-Hsueh Chen; Kui-Ming Wang; Xu Duan; Lian-Zhi Wu; Yi-Fang Zhao; Gang Chen (Cell and Tissue Research, 2022)

Vibrio salinus sp. nov., a marine nitrogen-fixing bacterium isolated from the lagoon sediment of an islet inside an atoll in the western Pacific Ocean - Wei-Sheng Huang; Li-Ting Wang; Jwo-Sheng Chen; Yen-Ting Chen; Sean Ting-Shyang Wei; Yin-Ru Chiang; Pei-Ling Wang; Tzong-Huei Lee; Shih-Ting Lin; Lina Huang; Wung Yang Shieh (Antonie van Leeuwenhoek, 2022)

Correction to: Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice - Xiongjie Fu; Hanhai Zeng; Jikuang Zhao; Guoyang Zhou; Hang Zhou; Jianfeng Zhuang; Chaoran Xu; Jianru Li; Yucong Peng; Yang Cao; Yin Li; Huaijun Chen; et al. (Translational Stroke Research, 2022)

Transport process and mechanism of the Hongshiyan rock avalanche triggered by the 2014 Ludian earthquake, China - Shi-lin Zhang; Yue-ping Yin; Hai-bo Li; Wen-pei Wang; Jia-wen Zhou (Landslides, 2022)

MiR-30c-1-3p targets matrix metalloproteinase 9 involved in the rupture of abdominal aortic aneurysms - Lin Yang; Hong-Gang Sui; Meng-Meng Wang; Jia-Yin Li; Xiao-Feng He; Jing-Yuan Li; Xiao-Zeng Wang (Journal of Molecular Medicine, 2022)
Abdominal aortic aneurysm (AAA) can be fatal if ruptured, but there is no predictive biomarker. Our aim was to evaluate the prognostic potential of microRNAs (miRNAs/miRs) in an AAA mouse model and patients with unruptured AAA (URAAA) and ruptured AAA (RAAA). Among the 64 miRNAs differentially expressed in mice with AAA compared to control, miR-30c-1-3p, miR-432-3p, miR-3154, and miR-379-5p had high homology with human miRNAs. MiR-30c-1-3p plasma levels were significantly lower in patients with RAAA than in those with URAAA or control and tended to negatively correlate with the maximum aortic diameter ( r = −0.3153, P = 0.06109). MiR-30c-1-3p targeted matrix metalloproteinase ( MMP)-9 mRNA through the coding region and downregulated its expression in vitro. MMP-9 plasma concentrations were significantly higher in the RAAA group than in the URAAA group ( P < 0.001) and were negatively associated with miR-30c-1-3p levels ( r = −0.3671, P = 0.01981) and positively–with the maximal aortic diameter ( r = 0.6251, P < 0.0001). The optimal cutoff values for MMP-9 expression and the maximal aortic diameter were 461.08 ng/ml and 55.95 mm, with areas under the curve of 0.816 and 0.844, respectively. Our results indicate that plasma levels of miR-30c-1-3p and MMP-9 may be candidate biomarkers of AAA progression. Key messages Downregulation of miR-30c-1-3p expression and upregulation of its potential target MMP-9 are predictors of the devastation of AAA. Downregulation of miR-30c-1-3p expression and its downstream impact on MMP-9 have a potential on predicting the development and rupture of AAA.

Halomonas salinarum sp. nov., a moderately halophilic bacterium isolated from saline soil in Yingkou, China - Ya-Lin Yin; Fang-Ling Li; Lei Wang (Archives of Microbiology, 2022)

Recognition of the Multi-class Schizophrenia Based on the Resting-State EEG Network Topology - Fali Li; Lin Jiang; Yuanyuan Liao; Cunbo Li; Qi Zhang; Shu Zhang; Yangsong Zhang; Li Kang; Rong Li; Dezhong Yao; Gang Yin; Peng Xu; et al. (Brain Topography, 2022)

Estrogenic and anti-neutrophilic inflammatory phenanthrenes from Juncus effusus L. - Hao-Chun Hu; Yi-Hong Tsai; Yu-Che Chuang; Kuei-Hung Lai; Yu-Ming Hsu; Tsong-Long Hwang; Chih-Chan Lin; Ferenc Fülöp; Yang-Chang Wu; Szu-Yin Yu; Yu-Ting Kuo; Fang-Rong Chang (Natural Product Research, 2022)

Correction to: Receptor-Interacting Protein 140 Enhanced Temozolomide-Induced Cellular Apoptosis Through Regulation of E2F1 in Human Glioma Cell Lines - Hong-Chieh Tsai; Kuo-Chen Wei; Pin-Yuan Chen; Chiung-Yin Huang; Ko-Ting Chen; Ya-Jui Lin; Hsiao-Wei Cheng; Chun-Hao Huang; Hsiang-Tsui Wang (NeuroMolecular Medicine, 2022)

Receptor-Interacting Protein 140 Enhanced Temozolomide-Induced Cellular Apoptosis Through Regulation of E2F1 in Human Glioma Cell Lines - Hong-Chieh Tsai; Kuo-Chen Wei; Pin-Yuan Chen; Chiung-Yin Huang; Ko-Ting Chen; Ya-Jui Lin; Hsiao-Wei Cheng; Chun-Hao Huang; Hsiang-Tsui Wang (NeuroMolecular Medicine, 2022)

Activation of Neuropeptide Y2 Receptor Can Inhibit Global Cerebral Ischemia-Induced Brain Injury - Reggie Hui-Chao Lee; Celeste Yin-Chieh Wu; Cristiane T. Citadin; Alexandre Couto e Silva; Harlee E. Possoit; Garrett A. Clemons; Christina H. Acosta; Victoria A. de la Llama; Jake T. Neumann; Hung Wen Lin (NeuroMolecular Medicine, 2022)

Effects of Biogas Slurry on Crop Yield, Physicochemical Properties and Aggregation Characteristics of Lime Concretion Soil in Wheat–Maize Rotation in the North China Plain - Jiao Tang; Anthony J. Davy; Wei Wang; Xihuan Zhang; Dafu Wu; Lin Hu; Jinzhong Yin (Journal of Soil Science and Plant Nutrition, 2022)

Long-term exercise pre-training attenuates Alzheimer’s disease–related pathology in a transgenic rat model of Alzheimer’s disease - Luodan Yang; Chongyun Wu; Yong Li; Yan Dong; Celeste Yin-Chieh Wu; Reggie Hui-Chao Lee; Darrell W. Brann; Hung Wen Lin; Quanguang Zhang (GeroScience, 2022)

miR-21-5p serves as a promoter in renal cell carcinoma progression through ARHGAP24 downregulation - Bin Meng; Pengfei Wang; Chaofei Zhao; Guangwei Yin; Xin Meng; Lin Li; Shengyong Cai; Chengquan Yan (Environmental Science and Pollution Research, 2022)

Characteristics of the chemical composition and source apportionment of PM2.5 for a one-year period in Wuhan, China - Xiaoyu Zhang; Guixiang Ji; Xiaowu Peng; Lingya Kong; Xin Zhao; Rongrong Ying; Wenjun Yin; Tian Xu; Juan Cheng; Lin Wang (Journal of Atmospheric Chemistry, 2022)

Community structure and assembly of denitrifying bacteria in epiphytic biofilms in a freshwater lake ecosystem - Guoqing Li; Dingbo Yan; Pinhua Xia; Haipeng Cao; Tao Lin; Yin Yi (Journal of Oceanology and Limnology, 2022)

Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight - Yu-Qian Song; Shi-Di Hu; Xu Lin; Xiang-He Meng; Xiao Wang; Yin-Hua Zhang; Cheng Peng; Rui Gong; Tao Xu; Tong Zhang; Chen-Zhong Li; Dao-Yan Pan; et al. (Journal of Molecular Medicine, 2022)
An increasing number of epidemiological studies have suggested that birth weight (BW) may be a determinant of bone health later in life, although the underlying genetic mechanism remains unclear. Here, we applied a pleiotropic conditional false discovery rate (cFDR) approach to the genome-wide association study (GWAS) summary statistics for lumbar spine bone mineral density (LS BMD) and BW, aiming to identify novel susceptibility variants shared between these two traits. We detected 5 novel potential pleiotropic loci which are located at or near 7 different genes ( NTAN1 , PDXDC1 , CACNA1G , JAG1 , FAT1P1 , CCDC170 , ESR1 ), among which PDXDC1 and FAT1P1 have not previously been linked to these phenotypes. To partially validate the findings, we demonstrated that the expression of PDXDC1 was dramatically reduced in ovariectomized (OVX) mice in comparison with sham-operated (SHAM) mice in both the growth plate and trabecula bone. Furthermore, immunohistochemistry assay with serial sections showed that both osteoclasts and osteoblasts express PDXDC1 , supporting its potential role in bone metabolism. In conclusion, our study provides insights into some shared genetic mechanisms for BMD and BW as well as a novel potential therapeutic target for the prevention of OP in the early stages of the disease development. Key messages We investigated pleiotropy-informed enrichment between LS BMD and BW. We identified genetic variants related to both LS BMD and BW by utilizing a cFDR approach. PDXDC1 is a novel pleiotropic gene which may be related to both LS BMD and BW. Elevated expression of PDXDC1 is related to higher BMD and lower ratio n-6/n-3 PUFA indicating a bone protective effect of PDXDC1.

Blood Transcriptome Analysis Reveals Gene Expression Differences between Yangtze Finless Porpoises from Two Habitats: Natural and Ex Situ Protected Waters - Wang Liu; Denghua Yin; Danqing Lin; Yan Yan; Xiaoyan Zhu; Congping Ying; Jialu Zhang; Pao Xu; Kai Liu (Fishes, 2022)
The Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis, YFP) is a critically endangered small odontocete species, mainly distributed in the middle and lower reaches of the Yangtze River, Poyang Lake, and Dongting Lake. Under the influence of human activities, many factors are threatening the survival and reproduction of YFPs in their natural habitat. Ex situ conservation is of great significance to strengthen the rescuing conservation of YFPs by providing suitable alternative habitats and promoting the reproduction and growth of the ex situ population. To reveal the differences in gene expression of YFPs in natural and ex situ protected waters, and to investigate the effects of environmental factors on YFPs and their mechanisms, we performed transcriptome sequencing for blood tissues of YFPs collected from natural waters and ex situ protected waters. Using RNA-seq we identified 4613 differentially expressed genes (DEGs), of which 4485 were up-regulated and 128 were down-regulated in the natural population. GO analysis showed that DEGs were significantly enriched in entries related to binding, catalytic activity, and biological regulation; KEGG analysis showed that DEGs were enriched mainly in signal transduction, endocrine system, immune system, and sensory system-related pathways. Further analysis revealed that water pollution in natural waters may affect the hormone secretion of YFPs by altering the expression pattern of endocrine genes, thus interfering with normal endocrine activities; noise pollution may induce oxidative stress and inflammatory responses in YFPs, thus impairing the auditory function of YFPs. This study provides a new perspective for further research on the effect of habitat conditions on the YFPs and suggests that improving the habitat environment may help in the conservation of YFPs.

Ocean Currents May Influence the Endolithic Bacterial Composition in Coral Skeletons - Po-Yu Liu; Sung-Yin Yang; Chih-Ying Lu; Naohisa Wada; Stéphane De Palmas; Shu-Shuo Yeh; Hideyuki Yamashiro; Sen-Lin Tang; Shan-Hua Yang (Frontiers in Marine Science, 2022)
Coral endolithic microbes can be an important nutrients support for hosts while under stresses. Previous studies have found that the endolithic microbial composition of a single coral species can be biogeographical diverse. However, the potential environmental factors, such as salinity, temperature, pH, and nutrient, that might influence the composition of the endolithic microbes remain unclear. In this study, we used both amplicon sequence variants (ASV) and a kmer-based taxonomic unit (KTU) to characterize the endolithic bacterial constitution of Isopora spp. located in the western Pacific Ocean—where it is subjected to the Kuroshio Current (in Okinawa, Japan and Green Island, Taiwan)—and the South China Sea (Dongsha Atoll). The endolithic bacterial community compositions showed a significant geographical difference, and we suggest that the ocean current and primary productivity are the most essential environmental factors influencing the bacterial communities in the skeleton of Isopora spp. In addition, our results showed that, technically, compared to ASV, bacterial composition based on KTU avoids extreme data, making it a suitable tool for explaining the associations between microbes and environmental factors.

Probiotic Potential and Effects on Gut Microbiota Composition and Immunity of Indigenous Gut Lactobacilli in Apis cerana - Mingkui Lv; Sifan Wang; Huajuan Yin; Kun Dong; Yiqiu Liu; Hongbin Pan; Qiuye Lin; Zhenhui Cao (Probiotics and Antimicrobial Proteins, 2022)

Stability Analysis of Slope Considering the Energy Evolution of Locked Segment - Xiangjie Yin; Hang Lin; Yifan Chen; Yi Tang; Yixian Wang; Yanlin Zhao; Weixun Yong (Geotechnical and Geological Engineering, 2022)

Pollution characteristics and emissions of typical organophosphate esters of a wastewater treatment plant - Hongling Yin; Yi Luo; Jiaojiao Song; Shiping Li; Shuyu Lin; Yuanming Xiong; Shuhong Fang; Juan Tang (Environmental Science and Pollution Research, 2022)

The impact of Alzheimer's disease susceptibility loci on lateral ventricular surface morphology in older adults - Shan Li; Na An; Nan Chen; Yin Wang; Lin Yang; Yalin Wang; Zhijun Yao; Bin Hu (Brain Structure and Function, 2022)

Knockout of GGPPS1 restrains rab37-mediated autophagy in response to ventilator-induced lung injury - Zexu Wang; Meizi Chen; Xia Pan; Li Wang; Cheng Yin; Qiuqi Lin; Jingjing Jiang; Yunlei Zhang; Bing Wan (Human Cell, 2022)

Transcriptomic analyses provide insight into adventitious root formation of Euryodendron excelsum H. T. Chang during ex vitro rooting - Yuping Xiong; Shuangyan Chen; Zhenpeng Wei; Xiaohong Chen; Beiyi Guo; Ting Zhang; Yuying Yin; Xincheng Yu; Jinhui Pang; Meiyun Niu; Xinhua Zhang; Yuan Li; et al. (Plant Cell, Tissue and Organ Culture (PCTOC), 2022)

Evaluation on explosion characteristics and parameters of pulverized coal for low-quality coal: experimental study and analysis - Hongwei Yan; Baisheng Nie; Chao Peng; Peijun Liu; Xiaotong Wang; Feifei Yin; Jie Gong; Yueying Wei; Shuangshuang Lin; Qiang Gao; Mingwei Cao (Environmental Science and Pollution Research, 2022)

Numerical Simulation of Mine Water Inflow with an Embedded Discrete Fracture Model: Application to the 16112 Working Face in the Binhu Coal Mine, China - Tao Chen; Huiyong Yin; Yutao Zhai; Lin Xu; Cuiyue Zhao; Lifeng Zhang (Mine Water and the Environment, 2022)

A bi-scale assessing framework for aesthetic ecosystem services of villages in a world heritage site - Yin-ping Ding; Zhi-lin Liu; Yuan-mei Jiao; Qiu-e Xu; Kan-feng Zhang; Cheng-jing Liu; Fan Chen (Journal of Mountain Science, 2022)

Impacts of anthropogenic and biophysical factors on ecological land using logistic regression and random forest: A case study in Mentougou District, Beijing, China - Chao Tian; Lin-lin Cheng; Ting-ting Yin (Journal of Mountain Science, 2022)

miRNA–mRNA Integrative Analysis Reveals the Roles of miRNAs in Hypoxia-Altered Embryonic Development- and Sex Determination-Related Genes of Medaka Fish - Keng Po Lai; Nathan Yi Kan Tam; Yuelong Chen; Chi Tim Leung; Xiao Lin; Chau Fong Tsang; Yin Cheung Kwok; William Ka Fai Tse; Shuk Han Cheng; Ting Fung Chan; Richard Yuen Chong Kong (Frontiers in Marine Science, 2022)
Recent studies have shown hypoxia to be an endocrine disruptor that impairs sex differentiation and reproductive function, leading to male-biased F1 populations in fish. However, the molecular mechanisms through which hypoxia alters fish sex differentiation and therefore sex ratios remain poorly understood. In order to understand the potential role of miRNAs in mediating hypoxia-altered sex determination and differentiation in fish, we conducted small RNA sequencing and transcriptome sequencing on marine medaka ( Oryzias melastigma ) embryos that were exposed to hypoxia (2.0 ± 0.2 mg O 2 L – 1) for 40 h (encompassing a critical window of sex determination). We identified dysregulated miRNAs and mRNAs in the hypoxia-exposed embryo, and bioinformatic analysis of the integrative small RNA sequencing and transcriptome sequencing results revealed hypoxia to cause alterations of genes related to embryonic development through miRNA regulation. Importantly, we have identified miRNA-mRNA pairs that were reported to play roles in gonad development (novel miR-145-col9a3 and novel miRNA-94- arid5b), in sex hormone response (novel miRNA-210-ca2, novel miRNA-106-nr2f2, nbr-miR-29c-nr4a1, and ola-miR-92b-akr1d1), and in sex characteristic development (novel miRNA-145-mns1, nle-miR-20-sord, and ipu-miR-219b-abcc8). Our findings highlighted the possible roles of miRNA–mRNA in regulation of embryonic development and sex determination in response to hypoxic stress.

Overexpression of long noncoding RNA MCM3AP-AS1 promotes osteogenic differentiation of dental pulp stem cells via miR-143-3p/IGFBP5 axis - Changwei Yang; Xuehong Xu; Pingting Lin; Bizhu Luo; Shufang Luo; Honglan Huang; Jianyu Zhu; Meie Huang; Shuhai Peng; Qianju Wu; Lu Yin (Human Cell, 2022)

Simultaneous high-efficiency removal of sulfamethoxazole and zinc (II) from livestock and poultry breeding wastewater by a novel dual-functional bacterium, Bacillus sp. SDB4 - Xi Chen; Hai Lin; Yingbo Dong; Bing Li; Tingting Yin; Chenjing Liu (Environmental Science and Pollution Research, 2022)

Assessing relative density of carbonate granular soil via dynamic cone penetration field and model tests - Lan Lin; Sa Li; Liqiang Sun; Tingting Li; Jiangsong Yin (Marine Georesources & Geotechnology, 2021)

Inhibition of Dectin-1 Ameliorates Neuroinflammation by Regulating Microglia/Macrophage Phenotype After Intracerebral Hemorrhage in Mice - Xiongjie Fu; Hanhai Zeng; Jikuang Zhao; Guoyang Zhou; Hang Zhou; Jianfeng Zhuang; Chaoran Xu; Jianru Li; Yucong Peng; Yang Cao; Yin Li; Huaijun Chen; et al. (Translational Stroke Research, 2021)

Genetic dissection of a pericentromeric region of barley chromosome 6H associated with Fusarium head blight resistance, grain protein content and agronomic traits - Yadong Huang; Lu Yin; Ahmad H. Sallam; Shane Heinen; Lin Li; Karen Beaubien; Ruth Dill-Macky; Yanhong Dong; Brian J. Steffenson; Kevin P. Smith; Gary J. Muehlbauer (Theoretical and Applied Genetics, 2021)

A Novel Approach to Surface Strain Measurement for Cylindrical Rock Specimens Under Uniaxial Compression Using Distributed Fibre Optic Sensor Technology - Shao-Qun Lin; Dao-Yuan Tan; Jian-Hua Yin; Hua Li (Rock Mechanics and Rock Engineering, 2021)

Rehabilitation of motor function in children with cerebral palsy based on motor imagery - Jiaxin Xie; Lin Jiang; Yanan Li; Baodan Chen; Fali Li; Yuanling Jiang; Dongrui Gao; Lili Deng; XuLin Lv; XianKun Ma; Gang Yin; Dezhong Yao; et al. (Cognitive Neurodynamics, 2021)

Experimental and Model Predictive Investigation into the Relationship of pH Alternation with Addition of Lime in Acid Tin Tailing Treatments - Feng Yin; Ying-Jie Li; Qun Zhao; Chen Li; Jie Li; Sen-Lin Tian (Bulletin of Environmental Contamination and Toxicology, 2021)

Identification and Characterization of Gene SpDMRT99B and Its Sex-Biased Expression Profile in the Mud Crab, Scylla paramamosain - Yin Zhang; Shaobin Fang; Fei Lin; Shengkang Li; Huaiping Zheng; Yueling Zhang; Mhd Ikhwanuddin; Hongyu Ma (Journal of Ocean University of China, 2021)

Bioinformatics-based study to identify immune infiltration and inflammatory-related hub genes as biomarkers for the treatment of rheumatoid arthritis - Sheng Fang; Xin Xu; Lin Zhong; An-quan Wang; Wei-lu Gao; Ming Lu; Zong-Sheng Yin (Immunogenetics, 2021)

Euphanoids A and B, two new lathyrane diterpenoids with nitric oxide (NO) inhibitory activity from Euphorbia kansuensis - Xue-Long Yan; Run-Zhu Fan; Jun Sang; Xing-Lin Xie; Gui-Hua Tang; Sheng Yin (Natural Product Research, 2021)

Geo-structures and deformation-failure characteristics of rockslide areas near the Baige landslide scar in the Jinsha River tectonic suture zone - Shi-lin Zhang; Yue-ping Yin; Xie-wen Hu; Wen-pei Wang; Zong-liang Li; Xin-ming Wu; Gang Luo; Sai-nan Zhu (Landslides, 2021)

3D finite-element modeling of Earth induced electromagnetic field and its potential applications for geomagnetic satellites - Hongbo Yao; Zhengyong Ren; Jingtian Tang; Yufeng Lin; Changchun Yin; Xiangyun Hu; Qinghua Huang; Keke Zhang (Science China Earth Sciences, 2021)

Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1 - Guang-Tong Jiang; Lin Shao; Shuo Kong; Meng-Liu Zeng; Jing-Jing Cheng; Tao-Xiang Chen; Song Han; Jun Yin; Wan-Hong Liu; Xiao-Hua He; Yu-Min Liu; Lanzi Gongga; et al. (Neuroscience Bulletin, 2021)

Genome-Wide Identification and Expression Analysis of the Barrel Medic (Medicago truncatula) and Alfalfa (Medicago sativa L.) Basic Helix-Loop-Helix Transcription Factor Family Under Salt and Drought Stresses - Boniface Ndayambaza; Xiaoyu Jin; Xueyang Min; Xiaoshan Lin; Xiaofan Yin; Wenxian Liu (Journal of Plant Growth Regulation, 2021)

Comparing the clinical outcomes across different sodium/glucose cotransporter 2 (SGLT2) inhibitors in heart failure patients: a systematic review and network meta-analysis of randomized controlled trials - Yao Hao Teo; Celine Shuen Yin Yoong; Nicholas L. Syn; Yao Neng Teo; Jia Yang Alex Cheong; Yoke-Ching Lim; Chi-Hang Lee; Tiong-Cheng Yeo; Ping Chai; Raymond C. C. Wong; Weiqin Lin; Ching-Hui Sia (European Journal of Clinical Pharmacology, 2021)

Degraded polysaccharides from Porphyra haitanensis: purification, physico-chemical properties, antioxidant and immunomodulatory activities - Yun-Feng Huo; Yin-Ting Li; Wei Xia; Chong Wang; Yuan-Yuan Xie; Yan-Bo Wang; Tao Zhou; Ling-Lin Fu (Glycoconjugate Journal, 2021)

Size Effect and Anisotropy in a Transversely Isotropic Rock Under Compressive Conditions - Kaihui Li; Zhen-Yu Yin; Dongya Han; Xiang Fan; Rihong Cao; Hang Lin (Rock Mechanics and Rock Engineering, 2021)

Magnetic Resonance Imaging-Guided and Navigated Individualized Repetitive Transcranial Magnetic Stimulation for Cognitive Impairment in Schizophrenia - Xu-Sha Wu; Tian-Cai Yan; Xian-Yang Wang; Yang Cao; Xiao-Fan Liu; Yu-Fei Fu; Lin Wu; Yin-Chuan Jin; Hong Yin; Long-Biao Cui (Neuroscience Bulletin, 2021)

Integration of small RNAs, degradome, and transcriptome sequencing provides insights into the differences between Shizhu ginseng and Yuan ginseng - Mengyuan Peng; Yanlin Chen; Wenjuan Wang; Zhihua He; Wangqiang Dai; Zhiyun Lin; Zemin Yang; Mengjuan Gong; Yongqin Yin; Bin Han; Yu Zeng; Yingfang Wang (Journal of Plant Biochemistry and Biotechnology, 2021)
Panax ginseng is one of the most popular herbs which have been used as an important traditional Chinese medicine since ancient times. Yuan ginseng and Shizhu ginseng,which belong to P. ginseng , are widely used as substitutes for wild ginseng in clinical practice. Clinical practice has proved that the clinical efficacy of Shizhu ginseng is better than Yuan ginseng. However, current research cannot completely explain this phenomenon. Considering that small RNA may be one of the pharmacodynamic substances of P. ginseng , it is challenging to investigate differential miRNAs between Shizhu ginseng and Yuan ginseng. In this study, the transcriptome, small RNAome and degradome of P. ginseng were studied by high-throughput sequencing. A total of 63,875 unigenes and 43,950,137 small RNA clean reads were obtained from the roots of P. ginseng . Among 3206 differentially expressed genes, 1190 genes were up-regulated in Yuan ginseng when compared with Shizhu ginseng. 24 known differential miRNAs and 7 novel differential miRNAs were obtained. The 304 targets of 24 differentially expressed miRNA (17 known and 7 novel) families are mainly related to energy metabolism, biotic stress and disease immunity in ginseng itself. Through the association analysis of mRNA and miRNA, our work gives a better understanding of the difference between Yuan ginseng and Shizhu ginseng. Considering the cross-kingdom regulation of plant miRNAs, our results may provide a foundation for understanding the miRNA-dependent clinical efficacy in P. ginseng .

Multifunctional graphene-based nanocomposites for simultaneous enhanced photocatalytic degradation and photothermal antibacterial activity by visible light - Ya-kun Lv; Lin Mei; Liu-xue Zhang; De-hong Yang; Zi-yu Yin (Environmental Science and Pollution Research, 2021)

Long-term effects of liquid swine manure land surface application in an apple orchard field on soil bacterial community and heavy metal contents in apple (Malus pumila Mill.) - Hongchao Jiao; Qin Yin; Cunhu Fan; Ling Wang; Jingpeng Zhao; Xiaojuan Wang; Kun Du; Hai Lin (Environmental Science and Pollution Research, 2021)

Biomechanical Evaluation of a Fin-type Implant Compared to Traditional Buttress Plate for the Stabilization of the Posteromedial Fragment in Tibial Plateau Split Fractures - Jian-Chih Chen; Kang-Ping Lin; Tien-Ching Lee; Yin-Chih Fu; Kun-Jhih Lin (Journal of Medical and Biological Engineering, 2021)

Study on the Quantitative Relationship Among Canopy Hyperspectral Reflectance, Vegetation Index and Cotton Leaf Nitrogen Content - Caixia Yin; Jiao Lin; Lulu Ma; Ze Zhang; Tongyu Hou; Lifu Zhang; Xin Lv (Journal of the Indian Society of Remote Sensing, 2021)
Study the response mechanism of Canopy spectral reflectance (CSR) to cotton nitrogen fertilizer, propose the sensitive band and center wavelength of cotton leaf nitrogen content (LNC), and compare the response characteristics of various vegetation indexes to LNC, propose a vegetation index that responds well to LNC and construct estimating model. This experiment sets five nitrogen fertilizer levels, namely N 0 (control), N 120 (120 kg/hm 2 ), N 240 (240 kg/hm 2 ), N 360 (360 kg/hm 2 ), N 480 (480 kg/hm 2 ). Among them, referring to the conventional nitrogen fertilizer is applied by local farmers (N 330 , 330 kg/hm 2 ). The results showed the following: (1) Visible light and near-infrared (NIR) can be used as two large ranges for precise monitoring of nitrogen, especially the CSR in the NIR range differs significantly under different nitrogen fertilizers. In the early stage of cotton growth, the CSR decreased with the nitrogen application rate increase, in a suitable nitrogen environment (360 kg/hm 2 ), and beyond N 360 , vice versa. In the later growth period, the CSR increases with the increase in nitrogen fertilizer. This trend is most evident in the short-wave NIR regions;(2) the range of 690–709 nm, 717–753 nm, and 940–958, which can be remote sensed by the spectral reflectance when cotton is affected in poor or rich nitrogen. The center wavelength corresponding to the nitrogen-sensitive band, respectively, are 697 nm, 735 nm, 953 nm, the band width can maintain 5–15 nm, generally not more than 20 nm;(3) compared with the ratio vegetation index, difference vegetation index, and normalized vegetation index, the combined vegetation index of more than two bands has a better effect on cotton LNC monitoring, of which the index (R 560 −R 670 )/(R 560 + R 670 −R 450 ), (R 700 −1.7 × R 670 + 0.7 × R 450 )/(R 700 + 2.3 × R 670 −1.3 × R 450 ) are significantly related to LNC in this papers, and the correlation coefficients can reach, respectively, 0.935 * and 0.936 * . These findings help to estimate the model of LNC. The model is as follows: Y = 19.883 × x + 42.285, where x refers to the combined vegetation index (R 700 −1.7 × R 670 + 0.7 × R 450 )/(R 700 + 2.3 × R 670 −1.3 × R 450 ), Y is LNC, but the model accuracy will be affected in the crop different phenological stage, and the model has the highest monitoring accuracy during the bud period.

Combination of XGBoost Analysis and Rule-Based Method for Intrapartum Cardiotocograph Classification - Pao-Lin Kuo; Lim Bee Yen; Yi-Chun Du; Po-Fan Chen; Pei-Yin Tsai (Journal of Medical and Biological Engineering, 2021)

Association between population density and infection rate suggests the importance of social distancing and travel restriction in reducing the COVID-19 pandemic - Heliang Yin; Tong Sun; Lan Yao; Yan Jiao; Li Ma; Lin Lin; J Carolyn Graff; Lotfi Aleya; Arnold Postlethwaite; Weikuan Gu; Hong Chen (Environmental Science and Pollution Research, 2021)

The glutathione S-transferase (PxGST2L) may contribute to the detoxification metabolism of chlorantraniliprole in Plutella xylostella(L.) - Fei Yin; Qingsheng Lin; Xiaoxiang Wang; Zhenyu Li; Xia Feng; Muhammad Zeeshan Shabbir (Ecotoxicology, 2021)
The diamondback moth ( Plutella xylostella L.), is an economic pest of cruciferous plants worldwide, which causes great economic loss to cruciferous plants production. However, the pest has developed resistance to insecticides. One of such insecticides is chlorantraniliprole. The study of the mechanisms underlying resistance is key for the effective management of resistance. In this study, a comparative proteomics approach was used to isolate and identify various proteins that differed between chlorantraniliprole-susceptible and -resistant strains of P. xylostella . Eleven proteins were significantly different and were successfully identified by MALDI-TOF-MS. Metabolism-related proteins accounted for the highest proportion among the eleven different proteins. The function of the PxGST2L protein was validated by RNAi. Knockdown of PxGST2L reduced the GST activity and increased the toxicity of chlorantraniliprole to the diamondback moth. The resistance ratio of diamondback moth to chlorantraniliprole was reduced from 1029 to 505. The results indicated that PxGST2L is partly responsible for chlorantraniliprole insecticide resistance in DBM. Our finding contributes to the understanding of the mechanism underlying resistance to chlorantraniliprole in the DBM, to develop effective resistance management tactics.

Sensitive Techniques for POCT Sensing on the Residues of Pesticides and Veterinary Drugs in Food - Lin Liu; Yueying Gao; Jinghan Liu; Ying Li; Ziye Yin; Yuanyuan Zhang; Fuwei Pi; Xiulan Sun (Bulletin of Environmental Contamination and Toxicology, 2021)

Current Progress on Antibiotic Sensing Based on Ratiometric Fluorescent Sensors - Jinghan Liu; Ying Li; Lin Liu; Yueying Gao; Yuanyuan Zhang; Ziye Yin; Fuwei Pi; Xiulan Sun (Bulletin of Environmental Contamination and Toxicology, 2021)

Aestuariibaculum sediminum sp. nov., a marine bacterium isolated from a tidal flat in Zhoushan - Zhi-Cheng Wu; Xin-Yin Zhang; Cong Sun; Lin Xu; Ge-Yi Fu; Xue-Wei Xu (Archives of Microbiology, 2021)

Quantification of SARS-CoV-2 antigen levels in the blood of patients with COVID-19 - Bin Su; Jiming Yin; Xingguang Lin; Tiantian Zhang; Xiao Yao; Ying Xu; Yao Lu; Wenzhi Wang; Kun Liu; Jie Zhang; Liangzhi Xie; Ronghua Jin; et al. (Science China Life Sciences, 2021)

Machine learning-based thermokarst landslide susceptibility modeling across the permafrost region on the Qinghai-Tibet Plateau - Guoan Yin; Jing Luo; Fujun Niu; Zhanju Lin; Minghao Liu (Landslides, 2021)

Long non-coding RNA FGD5-AS1 enhances osteosarcoma cell proliferation and migration by targeting miR-506-3p/RAB3D axis - Congda Li; Xiangbo Lin; Caiyun Zhang; Lei Wan; Jijun Yin; Bin Wang (Human Cell, 2021)

Capacity of transportation and spread of COVID-19—an ironical fact for developed countries - Li Ma; Zhuo Yu; Yan Jiao; Lin Lin; Wei Zhong; Sara W. Day; Arnold Postlethwaite; Hong Chen; Qiang Li; Heliang Yin; Gang Wang (Environmental Science and Pollution Research, 2021)

Investigating the use of environmental tableware based on the theory of planned behavior - Jui-Che Tu; Yu-Yin Chen; Yi-Lin Lee; Xiao-Lin Wang (Environment, Development and Sustainability, 2021)

Dissociable plasticity of visual-motor system in functional specialization and flexibility in expert table tennis players - Dazhi Yin; Xuefei Wang; Xiaoyou Zhang; Qiurong Yu; Yu Wei; Qing Cai; Mingxia Fan; Lin Li (Brain Structure and Function, 2021)

Vibrio nitrifigilis sp. nov., a marine nitrogen-fixing bacterium isolated from the lagoon sediment of an islet inside an atoll - Wei-Sheng Huang; Li-Ting Wang; Jwo-Sheng Chen; Yen-Ting Chen; Sean Ting-Shyang Wei; Yin-Ru Chiang; Pei-Ling Wang; Tzong-Huei Lee; Shih-Ting Lin; Lina Huang; Wung Yang Shieh (Antonie van Leeuwenhoek, 2021)

Sleep Characteristics and Cerebrospinal Fluid Progranulin in Older Adults: The CABLE Study - Meng Wang; Fu-Rong Sun; Yan-Lin Bi; Ya-Hui Ma; Jian-Jun Yin; Xue-Ning Shen; Xiao-Tong Wang; Lan Tan; Jin-Tai Yu (Neurotoxicity Research, 2021)

Identification of Regeneration and Hub Genes and Pathways at Different Time Points after Spinal Cord Injury - Sheng Fang; Lin Zhong; An-quan Wang; Hui Zhang; Zong-Sheng Yin (Molecular Neurobiology, 2021)

Blocking the JAK2/STAT3 and ERK pathways suppresses the proliferation of gastrointestinal cancers by inducing apoptosis - Xi Wang; Chunyan Dai; Yifei Yin; Lin Wu; Weiyang Jin; Yufei Fu; Zhe Chen; Ke Hao; Bin Lu (Journal of Zhejiang University-SCIENCE B, 2021)

Relationship between heavy metal consolidation and H2S removal by biochar from microwave pyrolysis of municipal sludge: effect and mechanism - Qingyuan Lin; Jun Zhang; Linlin Yin; Hao Liu; Wei Zuo; Yu Tian (Environmental Science and Pollution Research, 2021)

Comparing the cost, glycaemic control and medication adherence of utilizing patients’ own medicines (POMs) versus usual dispensing among diabetic patients in an outpatient setting - Phei Ching Lim; Yin Ying Chung; Shien Joo Tan; Te Ying Wong; Durga Devi Permalu; Thean Kheng Cheah; Shueh Lin Lim; Chong Yew Lee (DARU Journal of Pharmaceutical Sciences, 2021)

A quantitative study of the scale and distribution of tight gas reservoirs in the Sulige gas field, Ordos Basin, northwest China - Chao Luo; Ailin Jia; Jianlin Guo; Qing Tian; Junlei Wang; Hun Lin; Nanxin Yin; Xuanbo Gao (Frontiers of Earth Science, 2021)

Initiation of efficient C 4 pathway in response to low ambient CO 2 during the bloom period of a marine dinoflagellate - Hao Zhang; Youping Zhou; Tian‐Qi Liu; Xi‐Jie Yin; Lin Lin; Qiang Lin; Da‐Zhi Wang (Environmental Microbiology, 2021)
Summary Dinoflagellates are important primary producers and major causative agents of harmful algal blooms in the global ocean. Despite the great ecological significance, the photosynthetic carbon acquisition by dinoflagellates is still poorly understood. The pathways of photosynthetic carbon assimilation in a marine dinoflagellate Prorocentrum donghaiense under both in situ and laboratory‐simulated bloom conditions were investigated using a combination of metaproteomics, qPCR, stable carbon isotope and targeted metabolomics approaches. A rapid consumption of dissolved CO 2 to generate high biomass was observed as the bloom proceeded. The carbon assimilation genes and proteins including intracellular carbonic anhydrase 2, phosphoenolpyruvate carboxylase, phosphoenolpyruvate carboxykinase and RubisCO as well as their enzyme activities were all highly expressed at the low CO 2 level, indicating that C 4 photosynthetic pathway functioned in the blooming P . donghaiense cells. Furthermore, δ 13 C values and content of C 4 compound (malate) significantly increased with the decreasing CO 2 concentration. The transition from C 3 to C 4 pathway minimizes the internal CO 2 leakage and guarantees efficient carbon fixation at the low CO 2 level. This study demonstrates the existence of C 4 photosynthetic pathway in a marine dinoflagellate and reveals its important complementary role to assist carbon assimilation for cell proliferation during the bloom period.

Proteomic Response of the Brain to Hypoxic Stress in Marine Medaka Fish (Oryzias melastigma) - Keng Po Lai; Nathan Tam; Simon Yuan Wang; William Ka Fai Tse; Xiao Lin; Ting Fung Chan; Yin Tong; Jianwen Zhang; Doris Wai Ting Au; Rudolf Shiu Sun Wu; Richard Yuen Chong Kong (Frontiers in Marine Science, 2021)
Hypoxia is a serious issue that affects the marine environment, with a growing number of hypoxic “dead zones” occurring each year. Reports have indicated that hypoxia is detrimental to the reproductive function and sexual development of fish via the disruption of endocrine signaling in organs involved in the hypothalamus–pituitary–gonad axis, including the brain. While we previously reported that hypoxia induces transcriptome-wide alterations in the brain of marine medaka ( Oryzias melastigma ), whether these effects were reflected at the protein level remains unclear. Therefore, the present study used high-throughput proteomic sequencing along with bioinformatics analysis to assess the short-term and multi-generational effects of hypoxia on the brain proteome of O. melastigma . We identified 36,567 peptides and 7,599 proteins (1% false discovery rate in brain samples), with functions involved in cellular and metabolic processes such as signaling and reproductive processes as well as energy production and conversion. Furthermore, we determined that hypoxia resulted in the significant differential expressions of 33 upregulated and 69 downregulated proteins in the short-term exposure group and 24 upregulated and 52 downregulated proteins in the multi-generational exposure group. Pathway enrichment analysis of the deregulated proteins indicated that hypoxia could impair brain function by altering arachidonic acid metabolism, tight junctions, and adrenergic signaling under short-term hypoxic exposure and by altering p53 and PI3K–Akt signaling under multi-generational hypoxic exposure, which may lead to the onset of neurodegenerative disorders including Alzheimer’s disease and amyotrophic lateral sclerosis. Ingenuity pathway analysis of the deregulated proteins showed that hypoxia affected common signaling pathways in the brain (e.g., integrin, paxillin, and epithelial adherens junction signaling) under both short-term and multi-generational exposures. Hypoxia also deregulated pathways specific to short-term exposure (including integrin-linked kinase, calcium, and integrin signaling) and multi-generational exposure (including sphingosine-1-phosphate signaling, endocannabinoid neuronal synapse pathway, and endoplasmic reticulum stress pathway). Overall, our results provide additional insights into the mechanisms of hypoxia disrupting neuronal function at the protein level in marine medaka.

Cytotoxic meroterpenoids from the marine sponge Dactylospongia elegans - Hao-Bing Yu; Zi-Fei Yin; Bin-Bin Gu; Jian-Peng Zhang; Shu-Ping Wang; Fan Yang; Hou-Wen Lin (Natural Product Research, 2021)