An atlas of CNV maps in cattle, goat and sheep - Yongzhen Huang; Yunjia Li; Xihong Wang; Jiantao Yu; Yudong Cai; Zhuqing Zheng; Ran Li; Shunjin Zhang; Ningbo Chen; Hojjat Asadollahpour Nanaei; Quratulain Hanif; Qiuming Chen; et al. (Science China Life Sciences, 2021)

Mycorrhization of Quercus mongolica seedlings by Tuber melanosporum alters root carbon exudation and rhizosphere bacterial communities - Yanliang Wang; Ran Wang; Bin Lu; Alexis Guerin-Laguette; Xinhua He; Fuqiang Yu (Plant and Soil, 2021)

Correction to: The CsGPA1-CsAQPs module is essential for salt tolerance of cucumber seedlings - Yan Yan; Mintao Sun; Yansu Li; Jun Wang; Chaoxing He; Xianchang Yu (Plant Cell Reports, 2021)

Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1 - Guang-Tong Jiang; Lin Shao; Shuo Kong; Meng-Liu Zeng; Jing-Jing Cheng; Tao-Xiang Chen; Song Han; Jun Yin; Wan-Hong Liu; Xiao-Hua He; Yu-Min Liu; Lanzi Gongga; et al. (Neuroscience Bulletin, 2021)

Experimental study on the suffusion mechanism of gap-graded soils under an exceedance hydraulic gradient - Liang Chen; Yu Wan; Jian-Jian He; Chun-Mu Luo; Shu-Fa Yan; Xian-Feng He (Natural Hazards, 2021)

Activation of the Hippocampal LXRβ Improves Sleep-Deprived Cognitive Impairment by Inhibiting Neuroinflammation - Chen Qiu; Min Wang; Wen Yu; Zheng Rong; He-Sheng Zheng; Ting Sun; Shui-Bing Liu; Ming-Gao Zhao; Yu-Mei Wu (Molecular Neurobiology, 2021)

Rhizosphere-associated nosZII microbial community of Phragmites australis and its influence on nitrous oxide emissions in two different regions - Rui Su; Rui Huang; Jin Zeng; Dayong Zhao; Rujia He; Zhongbo Yu; Qinglong L. Wu (Journal of Soils and Sediments, 2021)

Study on the Relationship between the miRNA-centered ceRNA Regulatory Network and Fatigue - Xingzhe Yang; Feng Li; Jie Ma; Yan Liu; Xuejiao Wang; Ruochong Wang; Yifei Zhang; Wei Zhang; Qingyun He; Dandan Song; Jiaojiao Yu (Journal of Molecular Neuroscience, 2021)
In recent years, the incidence of fatigue has been increasing, and the effective prevention and treatment of fatigue has become an urgent problem. As a result, the genetic research of fatigue has become a hot spot. Transcriptome-level regulation is the key link in the gene regulatory network. The transcriptome includes messenger RNAs (mRNAs) and noncoding RNAs (ncRNAs). MRNAs are common research targets in gene expression profiling. Noncoding RNAs, including miRNAs, lncRNAs, circRNAs and so on, have been developed rapidly. Studies have shown that miRNAs are closely related to the occurrence and development of fatigue. MiRNAs can regulate the immune inflammatory reaction in the central nervous system (CNS), regulate the transmission of nerve impulses and gene expression, regulate brain development and brain function, and participate in the occurrence and development of fatigue by regulating mitochondrial function and energy metabolism. LncRNAs can regulate dopaminergic neurons to participate in the occurrence and development of fatigue. This has certain value in the diagnosis of chronic fatigue syndrome (CFS). CircRNAs can participate in the occurrence and development of fatigue by regulating the NF-κB pathway, TNF-α and IL-1β. The ceRNA hypothesis posits that in addition to the function of miRNAs in unidirectional regulation, mRNAs, lncRNAs and circRNAs can regulate gene expression by competitive binding with miRNAs, forming a ceRNA regulatory network with miRNAs. Therefore, we suggest that the miRNA-centered ceRNA regulatory network is closely related to fatigue. At present, there are few studies on fatigue-related ncRNA genes, and most of these limited studies are on miRNAs in ncRNAs. However, there are a few studies on the relationship between lncRNAs, cirRNAs and fatigue. Less research is available on the pathogenesis of fatigue based on the ceRNA regulatory network. Therefore, exploring the complex mechanism of fatigue based on the ceRNA regulatory network is of great significance. In this review, we summarize the relationship between miRNAs, lncRNAs and circRNAs in ncRNAs and fatigue, and focus on exploring the regulatory role of the miRNA-centered ceRNA regulatory network in the occurrence and development of fatigue, in order to gain a comprehensive, in-depth and new understanding of the essence of the fatigue gene regulatory network.

Consumer-driven nutrient release to the water by a small omnivorous fish enhanced ramet production but reduced the growth rate of the submerged macrophyte Vallisneria denseserrulata (Makino) Makino - Jinlei Yu; Manli Xia; Yanyan Zhao; Hu He; Baohua Guan; Feizhou Chen; Zhengwen Liu; Erik Jeppesen (Hydrobiologia, 2021)

Prenatal phthalate exposure reduction through an integrated intervention strategy - Wei Wu; Liu Cao; Ting-Ting Zheng; Shu-Yu Feng; Guan-Wei Ma; Ying-Ying He; Ping Wu (Environmental Science and Pollution Research, 2021)

Translocation versus ion trapping in the root uptake of 2,4-dichlorophenol by wheat seedlings - Qi Yu; Anfei He; Dongjin Shi; G. Daniel Sheng (Environmental Science and Pollution Research, 2021)

A combined radical and non-radical oxidation processes for efficient degradation of Acid Orange 7 in the homogeneous Cu(II)/PMS system: important role of chloride - Ying Huang; Qiongji Jiang; Xubiao Yu; Huihui Gan; Xia Zhu; Siyi Fan; Yan Su; Zhirui Xu; Cunrui He (Environmental Science and Pollution Research, 2021)

Irinotecan and berberine co-delivery liposomes showed improved efficacy and reduced intestinal toxicity compared with Onivyde for pancreatic cancer - Xue Wang; Ying Liu; Wanjia Xu; Lirui Jia; Dongxu Chi; Jiang Yu; Jiamei Wang; Zhonggui He; Xiaohong Liu; Yongjun Wang (Drug Delivery and Translational Research, 2021)

The impacts of different anticoagulants and long-term frozen storage on multiple metal concentrations in peripheral blood: a comparative study - Yu Bao; Xiaoting Ge; Longman Li; Junxiu He; Sifang Huang; Xiaoyu Luo; Xing Chen; Pan Chen; Xiaobo Yang (BioMetals, 2021)

DcNet: Dilated Convolutional Neural Networks for Side-Scan Sonar Image Semantic Segmentation - Xiaohong Zhao; Rixia Qin; Qilei Zhang; Fei Yu; Qi Wang; Bo He (Journal of Ocean University of China, 2021)

Interactive effects of nutrient availability, fluctuating supply, and plant parasitism on the post-invasion success of Bidens pilosa - Fang-Lei Gao; Qiao-Sheng He; Ru-Qian Xie; Jia-Hui Hou; Chen-Lu Shi; Jun-Min Li; Fei-Hai Yu (Biological Invasions, 2021)

Interaction of magnolia bark extracts with Staphylococcus aureus DNA and evaluation of the stability of their antibacterial activities - Shu-Mei Cui; Hai-yun Liang; Ting Li; Ke-Ke He; Yu-Mei Zheng; Meng Tang; Chong-rong Ke; Li-Ya Song (Archives of Microbiology, 2021)

Eddy diffusivity and coherent mesoscale eddy analysis in the Southern Ocean - Wenjin Sun; Jingsong Yang; Wei Tan; Yu Liu; Baojun Zhao; Yijun He; Changming Dong (Acta Oceanologica Sinica, 2021)

Geniposide-Loaded Liposomes for Brain Targeting: Development, Evaluation, and In Vivo Studies - Jinyan Wan; Yu Long; Songyu Liu; Yulu Zhang; Yan Xiang; Dan Li; Ai Shi; Yu Shuang; Ying Li; Yanan He; Nan Li; Yongmei Guan (AAPS PharmSciTech, 2021)

Structure–activity relationship studies on Pd176252 derivatives leading to discovery of novel GRP receptor antagonist with potent anticancer activity - Ming-jun Yu; Chao Li; Meng He; Yu-ting Zhu; Rui Yang; Sheng-song Deng; Xiao-ming Meng; Ri-sheng Yao (Medicinal Chemistry Research, 2021)

High-resolution genome-wide association study and genomic prediction for disease resistance and cold tolerance in wheat - Yunlong Pang; Yuye Wu; Chunxia Liu; Wenhui Li; Paul St. Amand; Amy Bernardo; Danfeng Wang; Lei Dong; Xiufang Yuan; Huirui Zhang; Meng Zhao; Linzhi Li; et al. (Theoretical and Applied Genetics, 2021)

Endoplasmic reticulum stress is involved in retinal injury induced by repeated transient spikes of intraocular pressure - Xue Yang; Xiaowei Yu; Zhenni Zhao; Yuqing He; Jiamin Zhang; Xiaoqian Su; Nannan Sun; Zhigang Fan (Journal of Zhejiang University-SCIENCE B, 2021)

Integration of small RNAs, degradome, and transcriptome sequencing provides insights into the differences between Shizhu ginseng and Yuan ginseng - Mengyuan Peng; Yanlin Chen; Wenjuan Wang; Zhihua He; Wangqiang Dai; Zhiyun Lin; Zemin Yang; Mengjuan Gong; Yongqin Yin; Bin Han; Yu Zeng; Yingfang Wang (Journal of Plant Biochemistry and Biotechnology, 2021)
Panax ginseng is one of the most popular herbs which have been used as an important traditional Chinese medicine since ancient times. Yuan ginseng and Shizhu ginseng,which belong to P. ginseng , are widely used as substitutes for wild ginseng in clinical practice. Clinical practice has proved that the clinical efficacy of Shizhu ginseng is better than Yuan ginseng. However, current research cannot completely explain this phenomenon. Considering that small RNA may be one of the pharmacodynamic substances of P. ginseng , it is challenging to investigate differential miRNAs between Shizhu ginseng and Yuan ginseng. In this study, the transcriptome, small RNAome and degradome of P. ginseng were studied by high-throughput sequencing. A total of 63,875 unigenes and 43,950,137 small RNA clean reads were obtained from the roots of P. ginseng . Among 3206 differentially expressed genes, 1190 genes were up-regulated in Yuan ginseng when compared with Shizhu ginseng. 24 known differential miRNAs and 7 novel differential miRNAs were obtained. The 304 targets of 24 differentially expressed miRNA (17 known and 7 novel) families are mainly related to energy metabolism, biotic stress and disease immunity in ginseng itself. Through the association analysis of mRNA and miRNA, our work gives a better understanding of the difference between Yuan ginseng and Shizhu ginseng. Considering the cross-kingdom regulation of plant miRNAs, our results may provide a foundation for understanding the miRNA-dependent clinical efficacy in P. ginseng .

The Preventive Effects of Lactobacillus casei on Acute Lung Injury Induced by Lipopolysaccharide - Lihui Zhao; Ying Mao; Haiming Yu; He Liu; Chao Wang; Jianwei Liu; Yutong Han; Yang Bi; Donghai Zhang (Indian Journal of Microbiology, 2021)

Exosomal long non-coding RNA SOX2 overlapping transcript enhances the resistance to EGFR-TKIs in non-small cell lung cancer cell line H1975 - Dongbo Zhou; Zhi Xia; Mingxuan Xie; Ying Gao; Qiao Yu; Baimei He (Human Cell, 2021)

Research progress in bioremediation of petroleum pollution - Yong Yang; Zhan-Wei Zhang; Rui-Xia Liu; Hai-Yan Ju; Xue-Ke Bian; Wan-Ze Zhang; Chuan-Bo Zhang; Ting Yang; Bing Guo; Chen-Lei Xiao; He Bai; Wen-Yu Lu (Environmental Science and Pollution Research, 2021)

Experimental noise and vibration characteristics of elevated urban rail transit considering the effect of track structures and noise barriers - Wei He; Kewen He; Chao Zou; Yanli Yu (Environmental Science and Pollution Research, 2021)

Effects of climate change on ecosystem services and their components in southern hills and northern grasslands in China - Lan Bai; Jialing Tian; Yu Peng; Yihang Huang; Xiaoao He; Xueying Bai; Ting Bai (Environmental Science and Pollution Research, 2021)

Apatite as an alternative petrochronometer to trace the evolution of magmatic systems containing metamict zircon - Hao-Cheng Yu; Kun-Feng Qiu; Callum J. Hetherington; David Chew; Ya-Qi Huang; Deng-Yang He; Jian-Zhen Geng; Hai-Yang Xian (Contributions to Mineralogy and Petrology, 2021)

Protective effect of Bombyx mori gloverin on intestinal epithelial cells exposure to enterotoxigenic E. coli - Qian Lin; Qingqing Fu; Guoqi Su; Daiwen Chen; Bing Yu; Yuheng Luo; Ping Zheng; Xiangbing Mao; Zhiqing Huang; Jie Yu; Junqiu Luo; Hui Yan; et al. (Brazilian Journal of Microbiology, 2021)

Effect of stress paths on failure mechanism and progressive damage of hard-brittle rock - Zi-quan Chen; Chuan He; Xiong-yu Hu; Chun-chi Ma (Journal of Mountain Science, 2021)

Baicalin attenuates adriamycin-induced nephrotic syndrome by regulating fibrosis procession and inflammatory reaction - Ning Tan; Chen-Xia Sun; Hui-Jun Zhu; De-Yu Li; Sheng-Guang Huang; Shou-Di He (Genes & Genomics, 2021)

A preliminary study on geomorphological characteristics and genetic mechanism of pockmarks in the Makran accretionary prism, northern Arabian Sea - Zhen Zhang; Xiguang Deng; Huiqiang Yao; Miao Yu; Haifeng Wang; Gaowen He; Bin Liu; Tingting Wu; Sanober Kahkashan; Syed Waseem Haider; Naimatullah Sohoo; Noor Ahmed Kalhoro (Geo-Marine Letters, 2021)

Quantitative proteomic analysis reveals that serine/threonine kinase is involved in Streptococcus suis virulence and adaption to stress conditions - Haodan Zhu; Junming Zhou; Dandan Wang; Zhengyu Yu; Bin Li; Yanxiu Ni; Kongwang He (Archives of Microbiology, 2021)

Antitubercular metabolites from the marine-derived fungus strain Aspergillus fumigatus MF029 - Zhijun Song; Yu Liu; Jieyu Gao; Jiansen Hu; Hongtao He; Shengwang Dai; Luoqiang Wang; Huanqin Dai; Lixin Zhang; Fuhang Song (Natural Product Research, 2021)

Investigation of Characteristics of Long Runout Landslides Based on the Multi-source Data Collaboration: A Case Study of the Shuicheng Basalt Landslide in Guizhou, China - Yu Zhuang; Aiguo Xing; Yangyang Leng; Muhammad Bilal; Yanbo Zhang; Kaiping Jin; Junyi He (Rock Mechanics and Rock Engineering, 2021)

Recycling of Paleo-Asian Ocean carbonates and its influence on the lithospheric composition of the North China Craton - Yongsheng Liu; Chunfei Chen; Detao He; La Zhang; Kaizhang Yu (Science China Earth Sciences, 2021)

GPR40 receptor agonist TAK-875 improves cognitive deficits and reduces β-amyloid production in APPswe/PS1dE9 mice - Chao Liu; Zhao-Yan Cheng; Qing-Peng Xia; Yu-Hui Hu; Chen Wang; Ling He (Psychopharmacology, 2021)

Associations of Sleep Characteristics with Cerebrospinal Fluid sTREM2 in Cognitively Normal Older Adults: the CABLE Study - He-Ying Hu; Ling-Zhi Ma; Hao Hu; Yan-Lin Bi; Ya-Hui Ma; Xue-Ning Shen; Ya-Nan Ou; Qiang Dong; Lan Tan; Jin-Tai Yu (Neurotoxicity Research, 2021)

Seismic response characteristics and deformation evolution of the bedding rock slope using a large-scale shaking table - Jianxian He; Shengwen Qi; Zhifa Zhan; Songfeng Guo; Chunlei Li; Bowen Zheng; Xiaolin Huang; Yu Zou; Guoxiang Yang; Ning Liang (Landslides, 2021)

PSMB4 inhibits cardiomyocyte apoptosis via activating NF-κB signaling pathway during myocardial ischemia/reperfusion injury - Chen Yang; Pengyi Yu; Fangfang Yang; Qian He; Bo Jiang; Liang Zheng; Qianyun Wang; Jun Wang; Hui Qiu; Hui Wang; Lei Zhang (Journal of Molecular Histology, 2021)

Effects of Mn2+ on neutral lipid content, C4 pathway, and related gene expression in Phaeodactylum tricornutum - Rong-Shi Chen; Li Zhang; Feng-Juan Wei; Lan-Ying Yuan; Pu Zhao; He-Yu Wang; Yi-Fu Gong (Journal of Applied Phycology, 2021)

5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivative attenuates lupus nephritis with less effect to thymocyte development - Fengjiao Wei; Xiaoqing Zhou; Huanpeng Chen; Xuyan Tian; Zhonghua Liu; Bolan Yu; Xixin He; Chuan Bai; Zhaofeng Huang (Immunologic Research, 2021)

Serotonin 2A receptor function and depression-like behavior in rats model of hypothyroidism - Zhicheng Jin; Jianer Ling; Jing Yu; Mengzi He; Pingping Ni; Fang Zhang; Yizhen Wang (Experimental Brain Research, 2021)

A comparison study of applying natural iron minerals and zero-valent metals as Fenton-like catalysts for the removal of imidacloprid - Siwan Liu; Wenwei Yu; Huang Cai; Faying Lai; Hansun Fang; Huajun Huang; Jinbao He (Environmental Science and Pollution Research, 2021)

Refractory organic compounds in coal chemical wastewater treatment by catalytic ozonation using Mn-Cu-Ce/Al2O3 - Kang-He Zhao; Yu-Long Ma; Feng Lin; Shao-Ying Ge; Li Zhu (Environmental Science and Pollution Research, 2021)

Genome-wide analysis of the GRAS gene family exhibited expansion model and functional differentiation in sea buckthorn (Hippophae rhamnoides L.) - Liyang Yu; Guoyun Zhang; Zhongrui Lyu; Caiyun He; Jianguo Zhang (Plant Biotechnology Reports, 2021)

Identification of Suitable Hydrologic Response Unit Thresholds for Soil and Water Assessment Tool Streamflow Modelling - Liupeng Jiang; Jinghai Zhu; Wei Chen; Yuanman Hu; Jing Yao; Shuai Yu; Guangliang Jia; Xingyuan He; Anzhi Wang (Chinese Geographical Science, 2021)

Nonstationary Responses of Demersal Fishes to Environmental Variations in Temperate Waters of the Northwestern North Pacific under a Changing Climate - Qingsong He; Shuyang Ma; Qinwang Xing; Wenchao Zhang; Haiqing Yu; Zhenjiang Ye (Fishes, 2021)
Although nonstationarity in marine ecosystems has attracted great attention, the nonstationary responses of demersal fishes to environmental variations induced by the changing climate are still not well understood. Here, we collected 21 time series of demersal fishes from 1956 to 2015 to investigate the climate-induced nonstationary responses in temperate waters of the northwestern North Pacific (NWP). We showed that these demersal fishes experienced state shifts in approximately 1986/87, accompanied by abrupt warming over this region. Moreover, the relationships between demersal fishes and sea surface temperature (SST) were found to change between the two identified eras (i.e., a weak relationship before 1986 and a strong negative relationship after 1986), which may be primarily caused by the alternating dominance of the East Asian winter monsoon and mega-ENSO on SST in temperate waters of the NWP. The identified climate-induced nonstationary responses of demersal fishes to SST variability in this study may provide implications for understanding climate-induced biological dynamics, predicting demersal fish fluctuations, coping with potential ecological risks, and the sustainable exploitation of fishery resources in the future climate. Note that the impact of fishing on the demersal fishes in temperate waters of the NWP was not assessed in this study due to the lack of fishing effort data and therefore the conclusions of our research should be approached with caution.

Research on Improving the Working Efficiency of Hydraulic Jet Submarine Cable Laying Machine - Zhifei Lu; Chen Cao; Yongqiang Ge; Jiamin He; Zhou Yu; Jiawang Chen; Xinlong Zheng (Journal of Marine Science and Engineering, 2021)
The anchoring and hooking of ships, bedrock friction and biological corrosion threaten the safety and stability of submarine cables. A hydraulic jet submarine cable laying machine manages to bury the submarine cables deep into the seabed, and effectively reduces the occurrence of external damage to the submarine cables. This machine uses a hydraulic jet system to realize trenching on the seabed. However, the hydraulic jet submarine cable laying machine has complicated operation and high power consumption with high requirements on the mother ship, and it is not yet the mainstream trenching method. In this paper, a mathematical model for the hydraulic jet nozzle of the submarine cable laying machine is established, and parameters that affect the trenching efficiency are studied. The effects of jet target distance, flow, angle and nozzle spacing on the working efficiency of the burying machine are analyzed by setting up a double-nozzle model. The results of the theory, numerical simulation and experiment show that the operational efficiency of the hydraulic jet submarine cable laying machine can be distinctly improved by setting proper jet conditions and parameters.

Vitamin D status and vitamin D receptor genotypes in celiac disease: a meta-analysis - Chao Lu; Weihua Zhou; Xinjue He; Xinxin Zhou; Chaohui Yu (Critical Reviews in Food Science and Nutrition, 2021)

CsUFO is involved in the formation of flowers and tendrils in cucumber - Yue Chen; Haifan Wen; Jian Pan; Hui Du; Keyan Zhang; Leyu Zhang; Yao Yu; Huanle He; Run Cai; Junsong Pan; Gang Wang (Theoretical and Applied Genetics, 2021)

Identification of a delayed leaf greening gene from a mutation of pummelo - Hui-Wen Yu; Zhi-Hao Lu; Xia Wang; Dan Liu; Jia-Xian He; Xiao-Lin Jiang; Ling-Jun Ke; Wen-Wu Guo; Xiu-Xin Deng; Qiang Xu (Science China Life Sciences, 2021)

A Hu sheep genome with the first ovine Y chromosome reveal introgression history after sheep domestication - Ran Li; Peng Yang; Ming Li; Wenwen Fang; Xiangpeng Yue; Hojjat Asadollahpour Nanaei; Shangquan Gan; Duo Du; Yudong Cai; Xuelei Dai; Qimeng Yang; Chunna Cao; et al. (Science China Life Sciences, 2021)

The optical and molecular signatures of DOM under the eutrophication status in a shallow, semi-enclosed coastal bay in southeast China - Chen Zhao; Yuping Zhou; Yu Pang; Yanzhen Zhang; Wei Huang; Yuntao Wang; Ding He (Science China Earth Sciences, 2021)

Ectopic expression of DoFLS1 from Dendrobium officinale enhances flavonol accumulation and abiotic stress tolerance in Arabidopsis thaliana - Zhenming Yu; Wei Dong; Jaime A. Teixeira da Silva; Chunmei He; Can Si; Jun Duan (Protoplasma, 2021)

LncRNA KCNQ1OT1 is a key factor in the reversal effect of curcumin on cisplatin resistance in the colorectal cancer cells - Zhi-hai Zheng; He-yi You; Yu-jie Feng; Zhong-tao Zhang (Molecular and Cellular Biochemistry, 2021)

The Ulva prolifera genome reveals the mechanism of green tides - Yuan He; Songdong Shen; Dachun Yu; Yehua Wang; Jiao Yin; Zongling Wang; Yuantu Ye (Journal of Oceanology and Limnology, 2021)

The contrasting relationships of relative humidity with influenza A and B in a humid subtropical region - Qian Wu; Jun He; Wen-Yan Zhang; Ke-Fu Zhao; Jing Jin; Jun-Ling Yu; Qing-Qing Chen; Sai Hou; Meng Zhu; Zhiwei Xu; Hai-Feng Pan (Environmental Science and Pollution Research, 2021)

Retrospective surveillance of porcine circovirus 4 in pigs in Inner Mongolia, China, from 2016 to 2018 - Zhuo Ha; Chengdong Yu; Changzhan Xie; Guanyu Wang; Ying Zhang; Pengfei Hao; Jinfeng Li; Zhuoxin Li; Yanwei Li; Fulong Rong; Fulong Nan; He Zhang; et al. (Archives of Virology, 2021)

Heavy Metals in Indoor Dust Across China: Occurrence, Sources and Health Risk Assessment - Baolin Liu; Fei Huang; Yong Yu; Xuedong Li; Yaowei He; Lei Gao; Xin Hu (Archives of Environmental Contamination and Toxicology, 2021)

Marinifaba aquimaris gen. nov., sp. nov., a novel chitin‐degrading gammaproteobacterium in the family Alteromonadaceae isolated from seawater of the Mariana Trench - Xin Sui; Xiao-yan He; Ning-hua Liu; Yan-ru Dang; Qian-qian Cha; Mei-ling Sun; Chun-yang Li; Hui-hui Fu; Xiao-yan Song; Qi-long Qin; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Above‐ and belowground biodiversity jointly drive ecosystem stability in natural alpine grasslands on the Tibetan Plateau - Litong Chen; Lin Jiang; Xin Jing; Jiuluan Wang; Yu Shi; Haiyan Chu; Jin‐Sheng He (Global Ecology and Biogeography, 2021)
Aim Most existing studies that examined the biotic mechanisms of ecosystem stability have focused on aboveground biodiversity. Whether and how belowground biodiversity affects the stability of natural ecosystems is largely unknown. In the present study, we investigated the relationships between above‐ and belowground biodiversity and the temporal stability of grassland biomass production across a large gradient of soil and climatic conditions. Location Tibetan Plateau. Time period 2001–2016. Major taxa studied Alpine grass and soil bacteria, arbuscular mycorrhiza (AM) fungi and fauna. Methods We coupled a field biodiversity survey conducted in 54 alpine grassland ecosystems across the Tibetan Plateau with a satellite‐sensed proxy (enhanced vegetation index, EVI) of ecosystem productivity during 2001–2016. The temporal stability of primary productivity was calculated as the ratio of the mean annual peak EVI to the standard deviation of the annual peak EVI over this period. Plant diversity was determined using a classic vegetation survey approach, soil bacterial and AM fungal diversity were measured using a high‐throughput sequencing approach, and soil fauna was counted and identified at the order level after being extracted using a modified Berlese–Tullgren method. Results Our results demonstrated that both above‐ and belowground biodiversity were positively associated with ecosystem stability. Belowground biodiversity not only affected ecosystem stability directly, but also influenced it indirectly through plant diversity and soil fertility. Furthermore, soil pH, climate and its variability strongly influenced soil biodiversity, which in turn influenced ecosystem stability. Main conclusions Our study demonstrates the indispensable role of belowground biodiversity in regulating ecosystem stability, emphasizing the necessity of conserving this ‘hidden’ biodiversity in fragile alpine ecosystems facing ongoing environmental change.

Analysis of unigenes involved in lateral root development in Bupleurum chinense and B. scorzonerifolium - Ma Yu; Hua Chen; Qian Liu; Jing Huang; Kassa Semagn; Dan Liu; Yuchan Li; Bin Yang; Yilian He; Chun Sui; Dabin Hou; Jianhe Wei (Planta, 2021)

Genome-Wide Identification and Expression Analysis of Heavy Metal Stress–Responsive Metallothionein Family Genes in Nicotiana tabacum - Qin Yu; Linshen He; Chunsong Huo; Xiaohan Jiang; Hua Chen; Run Wang; Minzhi Tang; Ling Dong; Ji Chen; Yonghao Li; Shunqin Zhu; Wanhong Liu (Plant Molecular Biology Reporter, 2021)

Genetic Architecture of Childhood Kidney and Urological Diseases in China - Ye Fang; Hua Shi; Tianchao Xiang; Jiaojiao Liu; Jialu Liu; Xiaoshan Tang; Xiaoyan Fang; Jing Chen; Yihui Zhai; Qian Shen; Guomin Li; Li Sun; et al. (Phenomics, 2021)
Kidney disease is manifested in a wide variety of phenotypes, many of which have an important hereditary component. To delineate the genotypic and phenotypic spectrum of pediatric nephropathy, a multicenter registration system is being implemented based on the Chinese Children Genetic Kidney Disease Database (CCGKDD). In this study, all the patients with kidney and urological diseases were recruited from 2014 to 2020. Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features. The genetic diagnosis was confirmed in 883 of 2256 (39.1%) patients from 23 provinces in China. Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome (SRNS, 23.5%), glomerulonephritis (GN, 32.2%), congenital anomalies of the kidney and urinary tract (CAKUT, 21.2%), cystic renal disease (3.9%), renal calcinosis/stone (3.6%), tubulopathy (9.7%), and chronic kidney disease of unknown etiology (CKDu, 5.8%). The pathogenic variants of 105 monogenetic disorders were identified. Ten distinct genomic disorders were identified as pathogenic copy number variants (CNVs) in 11 patients. The diagnostic yield differed by subgroups, and was highest in those with cystic renal disease (66.3%), followed by tubulopathy (58.4%), GN (57.7%), CKDu (43.5%), SRNS (29.2%), renal calcinosis /stone (29.3%) and CAKUT (8.6%). Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions. We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed. Our data demonstrate the utility of family-based exome sequencing, and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease.

Serum Calcium Predicts Cognitive Decline and Clinical Progression of Alzheimer’s Disease - Ling-Zhi Ma; Zi-Xuan Wang; Zuo-Teng Wang; Xiao-He Hou; Xue-Ning Shen; Ya-Nan Ou; Qiang Dong; Lan Tan; Jin-Tai Yu (Neurotoxicity Research, 2021)

Transcutaneous Auricular Vagus Nerve Stimulation: From Concept to Application - Yu Wang; Shao-Yuan Li; Dan Wang; Mo-Zheng Wu; Jia-Kai He; Jin-Ling Zhang; Bin Zhao; Li-Wei Hou; Jun-Ying Wang; Lei Wang; Yi-Fei Wang; Yue Zhang; et al. (Neuroscience Bulletin, 2021)

2-(3-Hydroxybenzyl)benzo[d]isothiazol-3(2H)-one Mannich base derivatives as potential multifunctional anti-Alzheimer’s agents - Yuxi He; Ganyuan Xiao; Guangjun Yu; Qing Song; Heng Zhang; Zhuoling Liu; Zhenghuai Tan; Yong Deng (Medicinal Chemistry Research, 2021)

Assessment of the Germination Potential of Brassica oleracea Seeds Treated with Karrikin 1 and Cyanide, Which Modify the Ethylene Biosynthetic Pathway - Abdul Sami; Shamsur Rehman; Muhammad Ayyoub Tanvir; Xiang Yu Zhou; Zong He Zhu; Kejin Zhou (Journal of Plant Growth Regulation, 2021)

Targeting a novel hsa_circ_0000520/miR-556-5p/NLRP3 pathway-mediated cell pyroptosis and inflammation attenuates ovalbumin (OVA)-induced allergic rhinitis (AR) in mice models - Xiaofeng Yu; Meng Wang; He Zhao; Zhiwei Cao (Inflammation Research, 2021)

Protective effects of Astragaloside IV against oxidative injury and apoptosis in cultured astrocytes by regulating Nrf2/JNK signaling - Jintao Yang; Chongyu Shao; Wentao Li; Haitong Wan; Yu He; Jiehong Yang (Experimental Brain Research, 2021)

Effect of ambient air pollution on tuberculosis risks and mortality in Shandong, China: a multi-city modeling study of the short- and long-term effects of pollutants - Yao Liu; Shi Zhao; Yifan Li; Wanmei Song; Cuixiang Yu; Lei Gao; Jinjun Ran; Daihai He; Huaichen Li (Environmental Science and Pollution Research, 2021)

Numerical simulation of hydraulic properties of soil in the GSPAC system under variable water-levels - Rui Dong; Yu-jiang He (Earth Science Informatics, 2021)

Simulation of social resilience affected by extreme events in ancient China - Hongming He; Claudio O. Delang; Jie Zhou; Yu Li; Wenming He (Climatic Change, 2021)

Drought tolerance in high-generation transgenic maize inbred lines overexpressing the betaine aldehyde dehydrogenase gene - He Zhao; Qi Zhang; Mo Zhang; Yu-Kun Jin; Zhen-Zhong Jiang; Nan Jiang; Qi Wang; Jing Qu; Shu-Yan Guan; Pi-Wu Wang (Cereal Research Communications, 2021)

Correction to: Synthetic antimicrobial agents inhibit aflatoxin production - Jing Li; Qing-Qing Zhi; Jie Zhang; Xiao-Yu Yuan; Li-Hong Jia; Yu-Lin Wan; Qiu-Yun Liu; Jian-Rong Shi; Zhu-Mei He (Brazilian Journal of Microbiology, 2021)

Synthetic antimicrobial agents inhibit aflatoxin production - Jing Li; Qing-Qing Zhi; Jie Zhang; Xiao-Yu Yuan; Li-Hong Jia; Yu-Lin Wan; Qiu-Yun Liu; Jian-Rong Shi; Zhu-Mei He (Brazilian Journal of Microbiology, 2021)

Efficiency comparison of B6(Cg)-Tyrc−2j /J and C57BL/6NTac embryos as hosts for the generation of knockout mice - Yu’e Ma; Lei He; Lijie Xiang; Jie Zhang; Jing Wang; Wenjing Zhu; Wenni Cao; Yichen Zhu; Man Gao; Fei Zhou; Zhiwei Liu (Transgenic Research, 2021)
Careful selection of the host embryo is critical to the efficient production of knockout (KO) mice when injecting mouse embryonic stem (mES) cells into blastocysts. B6(Cg)-Tyr c−2j /J (B6 albino) and C57BL/6NTac (B6NTac) strains of mice are widely used to produce host blastocysts for such procedures. Here, we tested these two strains to identify an appropriate match for modified agouti C57BL/6N (JM8A3.N1) mES cells. When comparing blastocyst yield, super-ovulated B6NTac mice produced more injectable blastocysts per female than B6 albino mice (8.2 vs. 5.4). There was no significant difference in birth rate when injected embryos were transferred to the same pseudopregnant recipient strain. However, the live birth rate was significantly higher for B6NTac blastocysts than B6 albino blastocysts (62.7% vs. 50.2%). In addition, the proportion of pups exhibiting high-level and complete chimerism, as identified by coat color, was also significantly higher in the B6NTac strain. There was no obvious difference in the efficiency of germline transmission (GLT) when compared between B6NTac and B6 albino host embryos (61.5% vs. 63.3% for mES clones; 64.5% vs. 67.9% for genes, respectively), thus suggesting that an equivalent GLT rate could be obtained with only a few blastocyst injections for B6NTac embryos. In conclusion, our data indicate that B6NTac blastocysts are a better choice for the microinjection of JM8A3.N1 mES cells than B6 albino blastocysts.

Generation and identification of endothelial-specific Hrh2 knockout mice - Rui Meng; Wen-Ke Cai; Wen-Mang Xu; Qiang Feng; Ping Wang; Yan-hua Huang; Yu-Xin Fan; Tao Zhou; Qin Yang; Zhi-Ran Li; Gong-Hao He (Transgenic Research, 2021)

LAI scale effect research based on compact airborne spectrographic imager data in the Heihe Oasis - Xiao-ai Dai; Chao Liu; Nai-wen Li; Mei-lian Wang; Yu-wei Yang; Xing-ping Yang; Shi-qi Zhang; Xu-wei He; Zheng-li Yang; Heng Lu; Jing-zhong Li; Ze-kun Wang (Journal of Mountain Science, 2021)

Comprehensive drought monitoring in Yunnan Province, China using multisource remote sensing data - Jin-liang Wang; Yuan-he Yu (Journal of Mountain Science, 2021)

Assessment of the Tidal Current Energy Resources and the Hydrodynamic Impacts of Energy Extraction at the PuHu Channel in Zhoushan Archipelago, China - He Wu; Huaming Yu; Yizhou Fang; Qingwei Zhou; Fengxuan Zhuo; Ryan M. Kelly (Journal of Ocean University of China, 2021)

Genome-wide identification of the ARRs gene family in tobacco (Nicotiana tabacum) - Jing Lv; Chang-bo Dai; Wei-feng Wang; Yu-he Sun (Genes & Genomics, 2021)

Spatio-temporal Variations of Sea Surface Wind in Coral Reef Regions over the South China Sea from 1988 to 2017 - Xin He; Zhenghua Chen; Yongqiang Lu; Wei Zhang; Kefu Yu (Chinese Geographical Science, 2021)

Complete genome sequence of a previously undescribed monopartite begomovirus and betasatellite infecting Malvastrum coromandelianum in Cambodia - Yafei Tang; Zhenggang Li; Xiaoman She; Lin Yu; Guobing Lan; Lihua Lv; Judith K. Brown; Zifu He (Archives of Virology, 2021)

Composition and co-occurrence patterns of Phragmites australis rhizosphere bacterial community - Siwen Hu; Rujia He; Wanjie Wang; Dayong Zhao; Jin Zeng; Rui Huang; Ming Duan; Zhongbo Yu (Aquatic Ecology, 2021)

Tritonibacter aquimaris sp. nov. and Tritonibacter litoralis sp. nov., two novel members of the Roseobacter group isolated from coastal seawater - Na Li; Xiao-yan He; Ning-hua Liu; Tie-ji Gu; Jian Li; Yu-hui Geng; Shan Zhang; Peng Wang; Hui-hui Fu; Mei Shi; Xiu-lan Chen; Yu-zhong Zhang; et al. (Antonie van Leeuwenhoek, 2021)

Chemical food contaminants during food processing: sources and control - Changjian Li; Changyan Li; Hang Yu; Yuliang Cheng; Yunfei Xie; Weirong Yao; Yahui Guo; He Qian (Critical Reviews in Food Science and Nutrition, 2021)

Emergence and prevalence of naturally occurring lower virulent African swine fever viruses in domestic pigs in China in 2020 - Encheng Sun; Zhenjiang Zhang; Zilong Wang; Xijun He; Xianfeng Zhang; Lulu Wang; Wenqing Wang; Lianyu Huang; Fei Xi; Haoyue Huangfu; Ghebremedhin Tsegay; Hong Huo; et al. (Science China Life Sciences, 2021)

Genome-wide association mapping for resistance to bacterial blight and bacterial leaf streak in rice - Nan Jiang; Jun Fu; Qin Zeng; Yi Liang; Yanlong Shi; Zhouwei Li; Youlun Xiao; Zhizhou He; Yuntian Wu; Yu Long; Kai Wang; Yuanzhu Yang; et al. (Planta, 2021)

KCNQ Channels in the Mesolimbic Reward Circuit Regulate Nociception in Chronic Pain in Mice - Hao-Ran Wang; Su-Wan Hu; Song Zhang; Yu Song; Xiao-Yi Wang; Lei Wang; Yang-Yang Li; Yu-Mei Yu; He Liu; Di Liu; Hai-Lei Ding; Jun-Li Cao (Neuroscience Bulletin, 2021)
Mesocorticolimbic dopaminergic (DA) neurons have been implicated in regulating nociception in chronic pain, yet the mechanisms are barely understood. Here, we found that chronic constructive injury (CCI) in mice increased the firing activity and decreased the KCNQ channel-mediated M-currents in ventral tegmental area (VTA) DA neurons projecting to the nucleus accumbens (NAc). Chemogenetic inhibition of the VTA-to-NAc DA neurons alleviated CCI-induced thermal nociception. Opposite changes in the firing activity and M-currents were recorded in VTA DA neurons projecting to the medial prefrontal cortex (mPFC) but did not affect nociception. In addition, intra-VTA injection of retigabine, a KCNQ opener, while reversing the changes of the VTA-to-NAc DA neurons, alleviated CCI-induced nociception, and this was abolished by injecting exogenous BDNF into the NAc. Taken together, these findings highlight a vital role of KCNQ channel-mediated modulation of mesolimbic DA activity in regulating thermal nociception in the chronic pain state.

Prediction model based on the Laplacian eigenmap method combined with a random forest algorithm for rainstorm satellite images during the first annual rainy season in South China - Xiao-yan Huang; Li He; Hua-sheng Zhao; Ying Huang; Yu-shuang Wu (Natural Hazards, 2021)

Stoichiometric relations of C, N, and P in urban top soils in Nanjing, China, and their biogeochemical implications - Jin-Ling Yang; Da-Gang Yuan; Yu-Guo Zhao; Yue He; Gan-Lin Zhang (Journal of Soils and Sediments, 2021)

RETRACTED ARTICLE: Two Metal Complexes: Selective Detection of Fe3+ Ion and Promotion Activity on Mesenchymal Stem Cells Differentiate Into Vascular Endothelial Cells - Qin-Ming Zhao; Zhong-You Xu; Hui-Peng Zhu; Yu-Xiang He; Mo Wang (Journal of Fluorescence, 2021)

Involvement of LIMK2 in actin cytoskeleton remodeling during the definitive endoderm differentiation - Yuping He; Lulu Zhang; Yaxin He; Hong Yu; Shengbiao Li; Qiuhong Li (In Vitro Cellular & Developmental Biology - Animal, 2021)

Hydrocotyle vulgaris L.: a new cadmium-tolerant landscape species and its physiological responses to cadmium exposure - Kehui Liu; Xiaolu Liang; Chunming Li; Leyi Wang; Xiaoyu He; Rilan Qin; Yi Li; Fangming Yu (Environmental Science and Pollution Research, 2021)

Prediction of methane production from co-digestion of lignocellulosic biomass with sludge based on the major compositions of lignocellulosic biomass - Pengfei Li; Chao He; Chongbo Cheng; Youzhou Jiao; Dekui Shen; Ran Yu (Environmental Science and Pollution Research, 2021)

Genome sequencing and functional annotation of Bacillus sp. strain BS-Z15 isolated from cotton rhizosphere soil having antagonistic activity against Verticillium dahliae - Zhong-Yi Chen; Xieerwanimu Abuduaini; Nuramina Mamat; Qi-Lin Yang; Meng-Jun Wu; Xin-Rui Lin; Ru Wang; Rong-Rong Lin; Wei-Jun Zeng; Huan-Chen Ning; He-Ping Zhao; Jin-Yu Li; et al. (Archives of Microbiology, 2021)

Bearing capacity behaviour of prestressed anchor cable under slope blasting excavation - Guofeng Li; Ning Li; Chong Yu; Mingming He (Arabian Journal of Geosciences, 2021)

Geological and climatic histories likely shaped the origins of terrestrial vertebrates endemic to the Tibetan Plateau - Jiekun He; Siliang Lin; Chenchen Ding; Jiehua Yu; Haisheng Jiang (Global Ecology and Biogeography, 2021)
Aim The Tibetan Plateau (TP) hosts many endemic species, but questions regarding when and from where these species originated have not been comprehensively answered. Here, we provide a synthesis of the biogeographical history of terrestrial vertebrates endemic to the TP and investigate the potential drivers of their spatio‐temporal origins. Location Tibetan Plateau and its surrounding regions. Time period Cenozoic. Major taxa studied Terrestrial vertebrates. Methods We used dispersal–extinction–cladogenesis models based on time‐calibrated phylogenies to reconstruct the ancestral ranges of 174 endemic TP species and compiled the ancestral ranges and age estimates of their dispersal events. We generated a possibility map of source areas for endemic TP species by counting the incidence of non‐TP sister clades in 110 km × 110 km grid cells. We used generalized linear mixed models to assess the relative importance of historical processes and environmental factors in explaining the geographical variations in the source areas. We created subsets based on four vertebrate classes to test whether the dispersal events varied spatially and temporally among taxonomic groups. Results We found that the endemic species colonized the TP as early as 55 Ma, and that the main colonization phase started to increase around 15 Ma and peaked after 6 Ma. The major source areas of endemic TP species include the Hengduan Mountains, the Himalayas, and Central Asia. Elevation difference had the strongest effect on the source areas, followed by geographical distance. The spatio‐temporal origins of species endemic to the TP and the potential drivers showed significant differences among vertebrate classes. Main conclusions Our study supports the hypothesis that endemic TP species originated from various zoogeographical regions at different times and highlights the important roles of the TP uplift and past climatic changes for determining the spatio‐temporal origins of endemic TP species.

Microbial metabolic response to winter warming stabilizes soil carbon - Jing Tian; Ning Zong; Iain P. Hartley; Nianpeng He; Jinjing Zhang; David Powlson; Jizhong Zhou; Yakov Kuzyakov; Fusuo Zhang; Guirui Yu; Jennifer A. J. Dungait (Global Change Biology, 2021)
Current consensus on global climate change predicts warming trends with more pronounced temperature changes in winter than summer in the Northern Hemisphere at high latitudes. Moderate increases in soil temperature are generally related to faster rates of soil organic carbon (SOC) decomposition in Northern ecosystems, but there is evidence that SOC stocks have remained remarkably stable or even increased on the Tibetan Plateau under these conditions. This intriguing observation points to altered soil microbial mediation of carbon‐cycling feedbacks in this region that might be related to seasonal warming. This study investigated the unexplained SOC stabilization observed on the Tibetan Plateau by quantifying microbial responses to experimental seasonal warming in a typical alpine meadow. Ecosystem respiration was reduced by 17%–38% under winter warming compared with year‐round warming or no warming and coincided with decreased abundances of fungi and functional genes that control labile and stable organic carbon decomposition. Compared with year‐round warming, winter warming slowed macroaggregate turnover rates by 1.6 times, increased fine intra‐aggregate particulate organic matter content by 75%, and increased carbon stabilized in microaggregates within stable macroaggregates by 56%. Larger bacterial “necromass” (amino sugars) concentrations in soil under winter warming coincided with a 12% increase in carboxyl‐C. These results indicate the enhanced physical preservation of SOC under winter warming and emphasize the role of soil microorganisms in aggregate life cycles. In summary, the divergent responses of SOC persistence in soils exposed to winter warming compared to year‐round warming are explained by the slowing of microbial decomposition but increasing physical protection of microbially derived organic compounds. Consequently, the soil microbial response to winter warming on the Tibetan Plateau may cause negative feedbacks to global climate change and should be considered in Earth system models.

Termite mounds reduce soil microbial diversity by filtering rare microbial taxa - Qing‐Lin Chen; Hang‐Wei Hu; Zhen‐Zhen Yan; Chao‐Yu Li; Bao‐Anh Thi Nguyen; Yong Zheng; Yong‐Guan Zhu; Ji‐Zheng He (Environmental Microbiology, 2021)
Summary Termites are ubiquitous insects in tropical and subtropical habitats, and some of them construct massive nests (‘mounds’), which substantially promote substrate heterogeneity by altering soil properties. Yet, the role of termite nesting process in regulating the distribution and diversity of soil microbial communities remains poorly understood, which introduces uncertainty in predictions of ecosystem functions of termite mounds in a changing environment. Here, by using amplicon sequencing, we conducted a survey of 134 termite mounds across >1500 km in northern Australia and found that termite mounds significantly differed from bulk soils in the microbial diversity and community compositions. Compared with bulk soils, termite nesting process decreased the microbial diversity and the relative abundance of rare taxa. Rare taxa had a narrower habitat niche breadth than dominant taxa and might be easier to be filtered by the potential intensive microbial competition during the nesting processes. We further demonstrated that the shift in pH induced by termite nesting process was a major driver shaping the microbial community profiles in termite mounds. Together, our work provides novel evidence that termite nesting is an important process in regulating soil microbial diversity, which advances our understanding of the functioning of termite mounds.

Effects of Spray Parameters on the Effective Spray Width of Single-Rotor Drone in Sugarcane Plant Protection - Ping Zhang; Wei Zhang; Hai-Tian Sun; Feng-Guang He; Hai-Ba Fu; Li-Qiang Qi; Li-Juan Yu; Li-Yu Jin; Bo Zhang; Jian-Sheng Liu (Sugar Tech, 2021)

In vitro and In vivo Antibacterial Effects of Nisin Against Streptococcus suis - Haodan Zhu; Lixiao Han; Yanxiu Ni; Zhengyu Yu; Dandan Wang; Junming Zhou; Bin Li; Wei Zhang; Kongwang He (Probiotics and Antimicrobial Proteins, 2021)

Human β-Defensin 118 Attenuates Escherichia coli K88–Induced Inflammation and Intestinal Injury in Mice - Qian Lin; Qingqing Fu; Xiang Li; Yuheng Luo; Junqiu Luo; Daiwen Chen; Xiangbing Mao; Bing Yu; Ping Zheng; Zhiqing Huang; Jie Yu; Hui Yan; et al. (Probiotics and Antimicrobial Proteins, 2021)

Selective Ferroptosis Inhibitor Liproxstatin-1 Attenuates Neurological Deficits and Neuroinflammation After Subarachnoid Hemorrhage - Yang Cao; Yin Li; Chao He; Feng Yan; Jian-Ru Li; Hang-Zhe Xu; Jian-Feng Zhuang; Hang Zhou; Yu-Cong Peng; Xiong-Jie Fu; Xiao-Yang Lu; Yuan Yao; et al. (Neuroscience Bulletin, 2021)

The physical–mechanical properties degradation mechanism and microstructure response of acid–alkali-contaminated Xiashu loess - Shaorui Sun; Wuchao Wang; Jihong Wei; Jinglei Song; Yongxiang Yu; Wei He; Jixing Zhang (Natural Hazards, 2021)

The Roles of Epinephelus coioides miR-122 in SGIV Infection and Replication - Hong-Yan Sun; Yu-Ling Su; Pin-Hong Li; Jia-Yang He; He-Jia Chen; Gang Wang; Shao-Wen Wang; Xiao-Hong Huang; You-Hua Huang; Qi-Wei Qin (Marine Biotechnology, 2021)
In mammals, mature miR-122 is 22 nucleotides long and can be involved in regulating a variety of physiological and biological pathways. In this study, the expression profile and effects of grouper Epinephelus coioides miR-122 response to Singapore grouper iridovirus (SGIV) infection were investigated. The sequences of mature microRNAs (miRNAs) from different organisms are highly conserved, and miR-122 from E. coioides exhibits high similarity to that from mammals and other fish. The expression of miR-122 was up-regulated during SGIV infection. Up-regulation of miR-122 could significantly enhance the cytopathic effects (CPE) induced by SGIV, the transcription levels of viral genes (MCP, VP19, LITAF and ICP18), and viral replication; reduce the expression of inflammatory factors (TNF-a, IL-6, and IL-8), and the activity of AP-1 and NF-κB, and miR-122 can bind the target gene p38α MAPK to regulate the SGIV-induced cell apoptosis and the protease activity of caspase-3. The results indicated that SGIV infection can up-regulate the expression of E. coioides miR-122, and up-regulation of miR-122 can affect the activation of inflammatory factors, the activity of AP-1 and NF-κB, and cell apoptosis to regulate viral replication and proliferation.

Correction to: Icariside II promotes the differentiation of human amniotic mesenchymal stem cells into dopaminergic neuron-like cells - Wei Kuang; Tao Liu; Fang He; Limei Yu; Qian Wang; Changyin Yu (In Vitro Cellular & Developmental Biology - Animal, 2021)

Icariside II promotes the differentiation of human amniotic mesenchymal stem cells into dopaminergic neuron-like cells - Wei Kuang; Tao Liu; Fang He; Limei Yu; Qian Wang; Changyin Yu (In Vitro Cellular & Developmental Biology - Animal, 2021)

Screening of binding proteins that interact with two components of the HOG MAPK pathway by the yeast two-hybrid method in Colletotrichum siamense - Xiaomiao Liao; Xiping Long; Qiguang He; Miao Song; Xiao Li; Wenbo Liu; Yu Zhang; Chunhua Lin; Weiguo Miao (European Journal of Plant Pathology, 2021)

Correction to: A Brush–Spin–Coating Method for Fabricating In Vitro Patient-Specific Vascular Models by Coupling 3D-Printing - Qing-Zhuo Chi; Li-Zhong Mu; Ying He; Yong Luan; Yu-Chen Jing (Cardiovascular Engineering and Technology, 2021)

A Brush–Spin–Coating Method for Fabricating In Vitro Patient-Specific Vascular Models by Coupling 3D-Printing - Qing-Zhuo Chi; Li-Zhong Mu; Ying He; Yong Luan; Yu-Chen Jing (Cardiovascular Engineering and Technology, 2021)

Revealing interactions between root phenolic metabolomes and rhizosphere bacterial communities in Populus euphratica plantations - Zhichao Xia; Yue He; Lei Yu; Zhijun Li; Helena Korpelainen; Chunyang Li (Biology and Fertility of Soils, 2021)

Mechanism of colluvial landslide induction by rainfall and slope construction: A case study - Zhou Zhou; Jun-hui Shen; Ying Li; Wei-feng Duan; Ri-chang Yang; Jun-cheng Shu; He-wei Li; Sheng-yu Tao; Sheng-zhe Zheng (Journal of Mountain Science, 2021)

Establishment of a micropropagation supporting technology for the Fraxinus mandshurica × Fraxinus sogdiana - Liming He; Yungang Xu; Fansuo Zeng; Hongmei Tian; Ying Xiao; Hualing Liu; Lei Yu; Yaguang Zhan (In Vitro Cellular & Developmental Biology - Plant, 2021)

miR-23b Attenuates LPS-Induced Inflammatory Responses in Acute Lung Injury via Inhibition of HDAC2 - Zhi-Feng Luo; Xiang-Hui Jiang; Huan Liu; Li-Yuan He; Xiong Luo; Fu-Chun Chen; Yu-Lin Tan (Biochemical Genetics, 2021)

IAP’s Solar-Powered Unmanned Surface Vehicle Actively Passes through the Center of typhoon Sinlaku (2020) - Hongbin Chen; Jun Li; Wenying He; Shuqing Ma; Yingzhi Wei; Jidong Pan; Yu Zhao; Xuefen Zhang; Shuzhen Hu (Advances in Atmospheric Sciences, 2021)

Assessing the effects of climate variable and timescale selection on uncertainties in dryness/wetness trends in conterminous China - Tianxiao Ma; Yu Liang; Michael G. Sunde; Matthew K. Lau; Bo Liu; Mia M. Wu; Hong S. He (International Journal of Climatology, 2021)
Analysing dryness/wetness trends, which is typically achieved by examining drought indices, is an essential approach for assessing extreme climate events. However, since there are differences among studies in terms of selected climate variables and timescales used to calculate drought indices, there is uncertainty regarding the magnitude and direction of the dryness/wetness, trend even for the same region. We used 40 years weather station data (1970–2010) and studied the uncertainties of dryness/wetness trends in conterminous China. The effects of selected climate variables, timescales and their interaction on the dryness/wetness trends were quantified by comparing the Standardized Precipitation Index, Standardized Precipitation Evapotranspiration Index (SPEI) with the Thornthwaite equation and SPEI with the Penman–Monteith equation at 3‐, 12‐ and 24‐month timescales. The results indicated that (a) higher uncertainties occurred in relatively arid and humid regions; (b) timescale tended to exaggerate the effect of climate variables, even though its effect was substantially lower than climate variables; (c) relative humidity and precipitation were the primary climate variables affecting observed dryness/wetness trend uncertainties. Since the key climate variables changed depending on the selected timescale, the role of timescale should be further examined the Inner Mongolia and Northeast regions. In general, the study results suggest that the trend analysis of dryness/wetness should include the interaction of both climate variable and timescale selection, particularly when a single drought index is used to estimate the dryness/wetness trend in diverse regions.

Global patterns in leaf stoichiometry across coastal wetlands - Yu‐Kun Hu; Xu‐Yan Liu; Nian‐Peng He; Xu Pan; Song‐Yuan Long; Wei Li; Man‐Yin Zhang; Li‐Juan Cui (Global Ecology and Biogeography, 2021)
Aim Coastal wetlands provide crucial ecosystem functions and services, such as coastal protection, nutrient retention and C sequestration. Despite the important roles in global C, N and P cycling, the global variation in leaf stoichiometry across coastal wetlands remains unclear. Location Global. Time period 1980–2018. Major taxa studied Vascular plants. Methods By compiling a global dataset of 698 data records in 205 sites, we carried out systematic analyses of the world‐wide trends and their determinants of leaf element contents and ratios of plants across coastal wetlands. Results Leaf N and P contents increased significantly, but C:N, C:P and N:P ratios decreased with increasing latitude in coastal wetlands. The mean annual temperature was the predominant driver of leaf N, P and C:N, whereas soil N:P was a good predictor of leaf C:P and N:P ratios. Furthermore, N increased faster with P in plant leaves of coastal wetlands compared with terrestrial ecosystems. Within coastal wetlands, herb‐dominated salt marshes had a significantly higher leaf P content, lower leaf N:P ratio and lower scaling exponent of leaf N to P than tree‐dominated mangroves. Main conclusions The similar latitudinal patterns of leaf stoichiometry in coastal wetlands compared with terrestrial ecosystems reflected the similar influences of temperature. However, different slopes of leaf P and N:P ratios and N and P scaling relationships between these two ecosystems suggested that different salinity and tidal inundation levels result in different strategies of N and P use in coastal wetland plants. These differences in leaf stoichiometry between ecosystems and between different types of coastal wetlands might need to be emphasized in future biogeochemical modelling owing to their different roles in global nutrient and carbon cycling.

EmhR is an indole‐sensing transcriptional regulator responsible for the indole‐induced antibiotic tolerance in Pseudomonas fluorescens - Jian‐Ting Han; Di‐Yin Li; Meng‐Yuan Zhang; Xiao‐Quan Yu; Xiang‐Xue Jia; Hang Xu; Xu Yan; Wen‐Juan Jia; Shaomin Niu; Megan L. Kempher; Xuanyu Tao; Yong‐Xing He (Environmental Microbiology, 2021)
Summary Indole is well known as an interspecies signalling molecule to modulate bacterial physiology; however, it is not clear how the indole signal is perceived and responded to by plant growth promoting rhizobacteria (PGPR) in the rhizosphere. Here, we demonstrated that indole enhanced the antibiotic tolerance of Pseudomonas fluorescens 2P24, a PGPR well known for its biocontrol capacity. Proteomic analysis revealed that indole influenced the expression of multiple genes including the emhABC operon encoding a major multidrug efflux pump. The expression of emhABC was regulated by a TetR‐family transcription factor EmhR, which was demonstrated to be an indole‐responsive regulator. Molecular dynamics simulation showed that indole allosterically affected the distance between the two DNA‐recognizing helices within the EmhR dimer, leading to diminished EmhR–DNA interaction. It was further revealed the EmhR ortholog in Pseudomonas syringae was also responsible for indole‐induced antibiotic tolerance, suggesting this EmhR‐dependent, indole‐induced antibiotic tolerance is likely to be conserved among Pseudomonas species. Taken together, our results elucidated the molecular mechanism of indole‐induced antibiotic tolerance in Pseudomonas species and had important implications on how rhizobacteria sense and respond to indole in the rhizosphere.

Dynamic relationship between meteorological conditions and air pollutants based on a mixed Copula model - Simin He; Zhiyao Li; Wenjie Wang; Mingxing Yu; Liangpo Liu; Md Nur Alam; Qian Gao; Tong Wang (International Journal of Climatology, 2021)
Many methods have been developed to verify the correlation between meteorological conditions and air pollutants; however, all have limitations that lead to biased or incomplete conclusions. Hence, improved methods are urgently required to describe this correlation comprehensively and accurately. In this study, we demonstrated the ability of the Copula function to apply time‐varying correlations between meteorological factors and atmospheric pollutants. A mixed Copula model was constructed using meteorological monitoring data for Beijing and Guangzhou from 2014 to 2019 to dynamically analyse the correlation characteristics and tail dependence between these factors. We then performed a correlation analysis for the data from the average, lower, and upper tails to obtain a more accurate and comprehensive correlation description. Dynamic analysis results demonstrated significant seasonal fluctuations between meteorological conditions and pollutants relationships. Moreover, the correlation coefficient variations differ according to their average and tail values. High humidity is more likely to be accompanied by increased NO 2 compared with average summer humidity. Our proposed model represents a novel application of the Copula function for determining the factors influencing air pollution. This model emphasizes the tail dependence between meteorological conditions and air pollutant concentrations and can be used to guide more targeted prevention and control strategies.

The effect of reef roughness on monochromatic wave breaking and transmission over fringing reefs - Yu Yao; Xiaoxiao Yang; Weijie Liu; Tiancheng He (Marine Georesources & Geotechnology, 2021)

Diagnostic incremental value of sputum in patients with pleural tuberculosis - Shuai Guo; Chao Han; Yu He; Mao-Shui Wang (Infectious Diseases, 2021)

Characteristic and evolution of HAT and HDAC genes in Gramineae genomes and their expression analysis under diverse stress in Oryza sativa - Jiaqi Hou; Ruifei Ren; Huangzhuo Xiao; Zhenfei Chen; Jinfu Yu; Haorui Zhang; Qipeng Shi; Haoli Hou; Shibin He; Lijia Li (Planta, 2021)

Kidney function change after transcatheter aortic valve replacement in patients with diabetes and/or hypertension - Jiaqi Fan; Changjie Yu; Kaida Ren; Wanbing Lin; Stella Ng; Zexin Chen; Xinping Lin; Lihan Wang; Qifeng Zhu; Yuxin He; Jubo Jiang; Xianbao Liu; et al. (Journal of Zhejiang University-SCIENCE B, 2021)

Purification and cDNA Cloning of Antimicrobial Peptides from the Skin Secretion of the Chinese Frog Rana chensinensis - Manyu Wu; Yang He; Djerry Yvan Arold Dinghani; Yuhua Wang; Yaohui Hu; Huan Wang; Bixiang Wang; Bo Lv; Hansong Yu; Liankui Wen (International Journal of Peptide Research and Therapeutics, 2021)

High-Level Expression and Purification of Melittin in Escherichia coli Using SUMO Fusion Partner - Qiu-chi Chen; Lei Liu; Tian-Yi Yu; Lu Tang; Mo-li Yin; Wen-he Zhu; Xiu-yun Jiang; Hui-yan Wang (International Journal of Peptide Research and Therapeutics, 2021)

Do Maternal Microbes Shape Newborn Oral Microbes? - Shengrong Wu; Fei Yu; Liya Ma; Youhong Zhao; Xin Zheng; Xiaodong Li; Zhiqiang Li; Xiangyi He; Jianye Zhou (Indian Journal of Microbiology, 2021)

Responses of submerged macrophytes and periphyton to warming under two nitrogen scenarios: A microcosm study - Yang Liu; Celina Aznarez; Erik Jeppesen; Hu He; Wei Li; Eti E. Levi; Juan Pablo Pacheco; Yu Cao (Hydrobiologia, 2021)

The metabolic and immunological characteristics of pregnant women with COVID-19 and their neonates - Jingjiao Zhou; Yudie Wang; Juan Zhao; Lixing Gu; Cheng Yang; Jun Wang; Heng Zhang; Yu Tian; Hu Tuo; Dan Li; Min Wei; Bing He (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Antimonate removal by diatomite modified with Fe-Mn oxides: application and mechanism study - Qiu-Yi Dong; Yu-Chun Fang; Bin Tan; Aura Ontiveros-Valencia; Ang Li; He-Ping Zhao (Environmental Science and Pollution Research, 2021)

Polybrominated diphenyl ethers in soils from Tianjin, North China: distribution, health risk, and temporal trends - Yu Han; Jiali Cheng; Lei He; Minna Zhang; Shan Ren; Jiazheng Sun; Xiangyang Xing; Zhenwu Tang (Environmental Geochemistry and Health, 2021)

Synthesis and biological evaluation of amino acid derivatives containing chrysin that induce apoptosis - Yang Li; Qizhi Zhang; Jun He; Wenmei Yu; Jie Xiao; Yu Guo; Xiaoming Zhu; Yunmei Liu (Natural Product Research, 2021)

SIMS U-Pb geochronology for the Jurassic Yanliao Biota from Bawanggou section, Qinglong (northern Hebei Province, China) - Zhiqiang Yu; Huaiyu He; Gang Li; Chenglong Deng; Haibing Wang; Xinxin Zhang; Qing Yang; Xiao-Ping Xia; Zhonghe Zhou; Rixiang Zhu (International Geology Review, 2021)

Adsorption Separation of CO2/CH4 from Landfill Gas by Ethanolamine-Modified Silica Gel - Yong Zhang; Kejin Chen; Chao Lv; Taijun Wu; Yonglin Wen; Hua He; Sheng Yu; Li’ao Wang (Water, Air, & Soil Pollution, 2021)

Mechanism for synoptic and intra-seasonal oscillation of visibility in Beijing-Tianjin-Hebei region - Xin Li; Caixia Yu; Xueliang Deng; Dongyan He; Zhijun Zhao; Huisi Mo; Jiajia Mo; Yanxing Wu (Theoretical and Applied Climatology, 2021)

Roles of FERONIA-like receptor genes in regulating grain size and quality in rice - Long Wang; Dandan Wang; Zhuhong Yang; Shun Jiang; Jianing Qu; Wei He; Zhenming Liu; Junjie Xing; Youchu Ma; Qinlu Lin; Feng Yu (Science China Life Sciences, 2021)

Discovery of new small-molecule cyclin-dependent kinase 6 inhibitors through computational approaches - Xiaojiao Luo; Yu Zhao; Pan Tang; Xingkai Du; Feng Li; Qingying Wang; Rong Li; Jun He (Molecular Diversity, 2021)

Aristocratic human papillomavirus drove cervical cancer: a study of the therapeutic potential of the combination of interferon with zinc - Yun-He Gao; Lei Yu; Zhong-Shan Liu; Yun-Feng Li (Molecular and Cellular Biochemistry, 2021)

Effects of Exogenous Organic Matter on the Migration of Organic Contaminants with Different Polarities in Soil - Yu Liang; Jiangtao He; Si Zhang; Qiwen Xia (International Journal of Environmental Research, 2021)

Modelling asymmetric deformation along a curved strike-slip basement-fault system - Bin Deng; Hemin Koyi; Caiwei Fan; Dong Lai; Yu He; Gang Yang; Qiang Luo; Xinjian Wang; Shugen Liu (International Journal of Earth Sciences, 2021)

Molecular epidemiology and antifungal susceptibilities of Cryptococcus species isolates from HIV and non-HIV patients in Southwest China - Si-Ying Wu; Mei Kang; Ya Liu; Zhi-Xing Chen; Yu-Ling Xiao; Chao He; Ying Ma (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Determination of thiamethoxam and its metabolite clothianidin residue and dissipation in cowpea by QuEChERS combining with ultrahigh-performance liquid chromatography–tandem mass spectrometry - Li Chen; Fugen Li; Chunhong Jia; Pingzhong Yu; Ercheng Zhao; Min He; Junjie Jing (Environmental Science and Pollution Research, 2021)

Spatial-temporal pattern evolution and driving force analysis of ecological environment vulnerability in Panzhihua City - Xiaoai Dai; Yu Gao; Xuwei He; Ting Liu; Bohan Jiang; Huaiyong Shao; Yuanzhi Yao (Environmental Science and Pollution Research, 2021)

Effects of chemical solutions on the hydromechanical behavior of a laterite/bentonite mixture used as an engineered barrier - Yong He; Ming-ming Wang; Dong-yu Wu; Ke-neng Zhang; Yong-gui Chen; Wei-min Ye (Bulletin of Engineering Geology and the Environment, 2021)

Cerebral blood flow alterations in hemodialysis patients with and without restless legs syndrome: an arterial spin labeling study - Hao Wang; Xue Han; Mei Jin; Li-yan Wang; Zong-li Diao; Wang Guo; Peng Zhang; Zheng Wang; Han Lv; He-yu Ding; Zheng-yu Zhang; Peng-fei Zhao; et al. (Brain Imaging and Behavior, 2021)

CAS-ESM2.0 Model Datasets for the CMIP6 Flux-Anomaly-Forced Model Intercomparison Project (FAFMIP) - Jiangbo Jin; He Zhang; Xiao Dong; Hailong Liu; Minghua Zhang; Xin Gao; Juanxiong He; Zhaoyang Chai; Qingcun Zeng; Guangqing Zhou; Zhaohui Lin; Yi Yu; et al. (Advances in Atmospheric Sciences, 2021)
The second version of the Chinese Academy of Sciences Earth System Model (CAS-ESM2.0) is participating in the Flux-Anomaly-Forced Model Intercomparison Project (FAFMIP) experiments in phase 6 of the Coupled Model Intercomparison Project (CMIP6). The purpose of FAFMIP is to understand and reduce the uncertainty of ocean climate changes in response to increased CO 2 forcing in atmosphere-ocean general circulation models (AOGCMs), including the simulations of ocean heat content (OHC) change, ocean circulation change, and sea level rise due to thermal expansion. FAFMIP experiments (including faf-heat, faf-stress, faf-water, faf-all, faf-passiveheat, faf-heat-NA50pct and faf-heat-NA0ct) have been conducted. All of the experiments were integrated over a 70-year period and the corresponding data have been uploaded to the Earth System Grid Federation data server for CMIP6 users to download. This paper describes the experimental design and model datasets and evaluates the preliminary results of CAS-ESM2.0 simulations of ocean climate changes in the FAFMIP experiments. The simulations of the changes in global ocean temperature, Atlantic Meridional Overturning Circulation (AMOC), OHC., and dynamic sea level (DSL), are all reasonably reproduced.

Datasets for the CMIP6 Scenario Model Intercomparison Project (ScenarioMIP) Simulations with the Coupled Model CAS FGOALS-f3-L - Shuwen Zhao; Yongqiang Yu; Pengfei Lin; Hailong Liu; Bian He; Qing Bao; Yuyang Guo; Lijuan Hua; Kangjun Chen; Xiaowei Wang (Advances in Atmospheric Sciences, 2021)
The datasets for the tier-1 Scenario Model Intercomparison Project (ScenarioMIP) experiments from the Chinese Academy of Sciences (CAS) Flexible Global Ocean-Atmosphere-Land System model, finite-volume version 3 (CAS FGOALS-f3-L) are described in this study. ScenarioMIP is one of the core MIP experiments in phase 6 of the Coupled Model Intercomparison Project (CMIP6). Considering future CO 2 , CH 4 , N 2 O and other gases’ concentrations, as well as land use, the design of ScenarioMIP involves eight pathways, including two tiers (tier-1 and tier-2) of priority. Tier-1 includes four combined Shared Socioeconomic Pathways (SSPs) with radiative forcing, i.e., SSP1-2.6, SSP2-4.5, SSP3-7.0 and SSP5-8.5, in which the globally averaged radiative forcing at the top of the atmosphere around the year 2100 is approximately 2.6, 4.5, 7.0 and 8.5 W m −2 , respectively. This study provides an introduction to the ScenarioMIP datasets of this model, such as their storage location, sizes, variables, etc. Preliminary analysis indicates that surface air temperatures will increase by about 1.89°C, 3.07°C, 4.06°C and 5.17°C by around 2100 under these four scenarios, respectively. Meanwhile, some other key climate variables, such as sea-ice extension, precipitation, heat content, and sea level rise, also show significant long-term trends associated with the radiative forcing increases. These datasets will help us understand how the climate will change under different anthropogenic and radiative forcings.

CAS-ESM2.0 Model Datasets for the CMIP6 Ocean Model Intercomparison Project Phase 1 (OMIP1) - Xiao Dong; Jiangbo Jin; Hailong Liu; He Zhang; Minghua Zhang; Pengfei Lin; Qingcun Zeng; Guangqing Zhou; Yongqiang Yu; Mirong Song; Zhaohui Lin; Ruxu Lian; et al. (Advances in Atmospheric Sciences, 2021)
As a member of the Chinese modeling groups, the coupled ocean-ice component of the Chinese Academy of Sciences’ Earth System Model, version 2.0 (CAS-ESM2.0), is taking part in the Ocean Model Intercomparison Project Phase 1 (OMIP1) experiment of phase 6 of the Coupled Model Intercomparison Project (CMIP6). The simulation was conducted, and monthly outputs have been published on the ESGF (Earth System Grid Federation) data server. In this paper, the experimental dataset is introduced, and the preliminary performances of the ocean model in simulating the global ocean temperature, salinity, sea surface temperature, sea surface salinity, sea surface height, sea ice, and Atlantic Meridional Overturning Circulation (AMOC) are evaluated. The results show that the model is at quasi-equilibrium during the integration of 372 years, and performances of the model are reasonable compared with observations. This dataset is ready to be downloaded and used by the community in related research, e.g., multi-ocean-sea-ice model performance evaluation and interannual variation in oceans driven by prescribed atmospheric forcing.

Highly enriched N‐containing organic molecules of Synechococcus lysates and their rapid transformation by heterotrophic bacteria - Qiang Zheng; Wenxin Lin; Yu Wang; Yunyun Li; Chen He; Yuan Shen; Weidong Guo; Quan Shi; Nianzhi Jiao (Limnology and Oceanography, 2021)
Phytoplankton are major contributors of labile dissolved organic matter to marine euphotic zone ecosystems. Viral‐mediated phytoplankton lysis releases a considerable amount of bioavailable cellular contents and facilitates localized heterotrophic bacterial growth. The rapid turnover times of this labile organic matter renders it difficult to trace their transformation within natural environments. In the present study, we used a model phototroph‐heterotroph coculture system to investigate the organic molecular variation during cyanophage‐induced Synechococcus lysis and post‐lysis periods using fluorescence spectroscopy and ultrahigh resolution mass spectrometry analyses. Approximately 80% of the Synechococcus lysates were respired to carbon dioxide within 2 days coupled to rapid regeneration of inorganic nutrients. Five fluorescent dissolved organic matter components were detected in the incubations including four humic‐like and one protein‐like components, and their abundances varied markedly with the succession of the viral lysis process. Viral lysis promoted the transformation of Synechococcus biomass to dissolved organic matter, and heterotrophic bacterial metabolism facilitated the transformation of organic molecules from relatively high (avg. ~ 430 Da) to low (avg. ~ 360 Da) molecular weight, corresponding to variation in their bioavailability. The Synechococcus ‐derived organic matter was highly enriched in N‐containing organic molecules. Identified metabolites within the cultures primarily comprised amino acids or oligopeptides and other low‐molecular‐weight organic acids, carbohydrates, nucleotides, lipids, biogenic amines, and porphyrins. Among these, oligopeptides, nucleotides, and lipid compounds significantly increased with viral lysis. These results provide insight into biogeochemical cycling mediated by viral shunts in oceans, thus deepening our understanding of microbial food webs at the molecular level.

Distribution of n ‐alkan‐2‐ones in Qionghai Lake sediments, southwest China, and its potential for late Quaternary paleoclimate reconstruction - Gen Wang; Yongli Wang; Zhifu Wei; Wei He; Ting Zhang; Xueyun Ma; Xiaoli Yu (Journal of Quaternary Science, 2021)
Studies on long‐chain n ‐alkan‐2‐ones from lake sediments remain sparse. In this study, we present an n ‐alkan‐2‐one record from Qionghai Lake, southwest China, to assess the paleoclimate significance of variations in their compositions. A homologous series of n ‐alkan‐2‐ones ranging from C 21 to C 35 were identified, with maximum concentrations of the C 29 or C 31 chain lengths and a strong odd‐over‐even predominance. This type of n ‐alkan‐2‐one is considered to derive mainly from microbial oxidation of the corresponding n ‐alkanes, and partial inputs from plants. The n ‐alkan‐2‐one‐derived average chain length (ACL) and carbon preference index (CPI) values changed significantly over the past 28k cal a bp , consistent with the sediment grain size and n ‐alkane proxies from the same core. Generally, the high CPI 27‐33 ‐ket and low ACL 27‐33 ‐ket values indicated cold and dry climates such as for the Last Glacial Maximum (23.2–19.7k cal a bp ), Heinrich 1 event (17.6–15.6k cal a bp ) and Younger Dryas (12.8–11.6k cal a bp ), but low CPI 27‐33 ‐ket and high ACL 27‐33 ‐ket values denoted a warm and humid Holocene Climatic Optimum (7.0–4.3k cal a bp ). Therefore, n ‐alkan‐2‐ones have great paleoclimatic potential and can be applied together with other biomarkers to reconstruct a reliable paleoclimate record in lake sediments.

Rapid and highly efficient genomic engineering with a novel iEditing device for programming versatile extracellular electron transfer of electroactive bacteria - Yang‐Yang Fan; Qiang Tang; Yang Li; Feng‐He Li; Jing‐Hang Wu; Wen‐Wei Li; Han‐Qing Yu (Environmental Microbiology, 2021)
Summary The advances in synthetic biology bring exciting new opportunities to reprogram microorganisms with novel functionalities for environmental applications. For real‐world applications, a genetic tool that enables genetic engineering in a stably genomic inherited manner is greatly desired. In this work, we design a novel genetic device for rapid and efficient genome engineering based on the i ntron‐encoded homing‐endonuclease empowered genome editing (iEditing). The iEditing device enables rapid and efficient genome engineering in Shewanella oneidensis MR‐1, the representative strain of the electroactive bacteria group. Moreover, combining with the Red or RecET recombination system, the genome‐editing efficiency was greatly improved, up to approximately 100%. Significantly, the iEditing device itself is eliminated simultaneously when genome editing occurs, thereby requiring no follow‐up to remove the encoding system. Then, we develop a new extracellular electron transfer (EET) engineering strategy by programming the parallel EET systems to enhance versatile EET. The engineered strains exhibit sufficiently enhanced electron output and pollutant reduction ability. Furthermore, this device has demonstrated its great potential to be extended for genome editing in other important microbes. This work provides a useful and efficient tool for the rapid generation of synthetic microorganisms for various environmental applications.

T4 ‐like myovirus community shaped by dispersal and deterministic processes in the South China Sea - Huifang Li; Lu Liu; Yu Wang; Lanlan Cai; Maoqiu He; Long Wang; Chen Hu; Nianzhi Jiao; Rui Zhang (Environmental Microbiology, 2021)
Summary As the most abundant and genetically diverse biological entities, viruses significantly influence ecological, biogeographical and evolutionary processes in the ocean. However, the biogeography of marine viruses and the drivers shaping viral community are unclear. Here, the biogeographic patterns of T4‐like viruses and the relative impacts of deterministic (environmental selection) and dispersal (spatial distance) processes were investigated in the northern South China Sea. The dominant viral operational taxonomic units were affiliated with previously defined Marine, Estuary, Lake and Paddy Groups. A clear viral biogeographic pattern was observed along the environmental gradient from the estuary to open sea. Marine Groups I and IV had a wide geographical distribution, whereas Marine Groups II, III and V were abundant in lower‐salinity continental or eutrophic environments. A significant distance‐decay pattern was noted for the T4‐like viral community, especially for those infecting cyanobacteria. Both deterministic and dispersal processes influenced viral community assembly, although environmental selection (e.g. temperature, salinity, bacterial abundance and community, etc.) had a greater impact than spatial distance. Network analysis confirmed the strong association between viral and bacterial community composition, and suggested a diverse ecological relationship (e.g. lysis, co‐infection or mutualistic) between and within viruses and their potential bacterial hosts.

Diversity and potential biogeochemical impacts of viruses in bulk and rhizosphere soils - Li Bi; Dan‐Ting Yu; Shuai Du; Li‐Mei Zhang; Li‐Yu Zhang; Chuan‐Fa Wu; Chao Xiong; Li‐Li Han; Ji‐Zheng He (Environmental Microbiology, 2021)
Summary Viruses can affect microbial dynamics, metabolism and biogeochemical cycles in aquatic ecosystems. However, viral diversity and functions in agricultural soils are poorly known, especially in the rhizosphere. We used virome analysis of eight rhizosphere and bulk soils to study viral diversity and potential biogeochemical impacts in an agro‐ecosystem. The order Caudovirales was the predominant viral type in agricultural soils, with Siphoviridae being the most abundant family. Phylogenetic analysis of the terminase large subunit of Caudovirales identified high viral diversity and three novel groups. Viral community composition differed significantly between bulk and rhizosphere soils. Soil pH was the main environmental driver of the viral community structure. Remarkably, abundant auxiliary carbohydrate‐active enzyme (CAZyme) genes were detected in viromes, including glycoside hydrolases, carbohydrate esterases and carbohydrate‐binding modules. These results demonstrate that virus‐encoded putative auxiliary metabolic genes or metabolic genes that may change bacterial metabolism and indirectly contribute to biogeochemical cycling, especially carbon cycling, in agricultural soil.

Variations of soil organic matters and plant cuticular waxes along an altitude gradient in Qinghai-Tibet Plateau - Luhua Yao; Na Guo; Yuji He; Yu Xiao; Yang Li; Jianhua Gao; Yanjun Guo (Plant and Soil, 2021)

Extracellular enzyme stoichiometry reveals the carbon and phosphorus limitations of microbial metabolisms in the rhizosphere and bulk soils in alpine ecosystems - Yongxing Cui; Haijian Bing; Linchuan Fang; Mao Jiang; Guoting Shen; Jialuo Yu; Xia Wang; He Zhu; Yanhong Wu; Xingchang Zhang (Plant and Soil, 2021)

The 3-ketoacyl-CoA synthase WFL is involved in lateral organ development and cuticular wax synthesis in Medicago truncatula - Tianquan Yang; Youhan Li; Yu Liu; Liangliang He; Aizhong Liu; Jiangqi Wen; Kirankumar S. Mysore; Million Tadege; Jianghua Chen (Plant Molecular Biology, 2021)

Experimental study on permeability response in fractured rock to the effect of hydro-mechanical coupling, fracture geometry, and component content - Tong Zhang; Xiang He; Yang Liu; Yixin Zhao; Ke Yang; Xiang Yu (Natural Hazards, 2021)

Identification of 5S and 45S rDNA sites in Chrysanthemum species by using oligonucleotide fluorescence in situ hybridization (Oligo-FISH) - Jun He; Sisi Lin; Zhongyu Yu; Aiping Song; Zhiyong Guan; Weimin Fang; Sumei Chen; Fei Zhang; Jiafu Jiang; Fadi Chen; Haibin Wang (Molecular Biology Reports, 2021)

Impact of North Atlantic SST and Tibetan Plateau forcing on seasonal transition of springtime South Asian monsoon circulation - Wei Yu; Yimin Liu; Xiu-Qun Yang; Guoxiong Wu; Bian He; Jinxiao Li; Qing Bao (Climate Dynamics, 2021)
The South Asian circulation and precipitation in spring shows a clear seasonal transition and interannual variation. We investigate how the North Atlantic sea surface temperature (SST) and Tibetan Plateau (TP) forcing affect this seasonal transition over South Asia on interannual timescale. Our results suggest that North Atlantic SST can affect the seasonal transition of South Asian monsoon via TP forcing in spring. The positive tripole pattern of North Atlantic SST anomaly during winter–spring can trigger a steady downstream Rossby wave train with cyclonic circulation over the southwestern TP. This forms a spring dipole mode of surface sensible heating and 10 m winds over the plateau, with a westerly (easterly) flow and positive (negative) surface sensible heating over its southern (northern) regions. A distinct land–air coupling configuration in May is then generated on the southwestern TP via such a positive TP dipole mode, which consists of anomalous positive precipitation, negative surface sensible heating and a baroclinic circulation structure with cyclonic circulation in the mid- to upper troposphere and a shallow anticyclonic circulation in the lower layer. The anticyclonic circulation is opposite to the summertime monsoon circulation. It weakens the cross-equatorial flow and water vapor transport to the South Arabian Sea and Bay of Bengal, resulting in in-situ precipitation reduction. Consequently, the seasonal transition in circulation over South Asia from winter to summer is delayed.

Lung injury induced by pyrrolizidine alkaloids depends on metabolism by hepatic cytochrome P450s and blood transport of reactive metabolites - Yisheng He; Wei Lian; Liang Ding; Xiaoyu Fan; Jiang Ma; Qing-Yu Zhang; Xinxin Ding; Ge Lin (Archives of Toxicology, 2021)

Fluid and ore-material source of the Xiajiaxiaohe gold deposit in central Yishu fault zone in Shandong, Eastern China - Yixin Dou; Guangzhou Mao; Lingqiang Meng; Xiaotong Liu; Pengrui An; Mingping Cao; Tieliang He; Liguo Song; Yu Wang; Yiwen Xu (Arabian Journal of Geosciences, 2021)

Effect of soil microstructure on the small-strain shear modulus of saline soil - Xingang Wang; Tangdai Xia; Longju Zhang; Zhi Ding; Shaoheng He; Yu Peng (Arabian Journal of Geosciences, 2021)

Profiles and Source Apportionment of Nonmethane Volatile Organic Compounds in Winter and Summer in Xi’an, China, based on the Hybrid Environmental Receptor Model - Jian Sun; Zhenxing Shen; Yue Zhang; Wenting Dai; Kun He; Hongmei Xu; Zhou Zhang; Long Cui; Xuxiang Li; Yu Huang; Junji Cao (Advances in Atmospheric Sciences, 2021)

Preparation of mPEG-b-PLA/TM-2 Micelle Lyophilized Products by Mixed Lyoprotectors and Antitumor Effect In Vivo - Ying Zhang; Yi Liu; Na Wang; Hongbing Liu; Jingxin Gou; Haibing He; Yu Zhang; Tian Yin; Yanjiao Wang; Xing Tang (AAPS PharmSciTech, 2021)

Intensified fragmentation and shrinkage of the polar climate zone in the Arctic - Yanlong Guan; Hongwei Lu; Li He; Yu Kang; Hari Adhikari; Jiankai Zhang; Petri Pellikka (International Journal of Climatology, 2021)
Using both observation and CMIP5 simulation data, this study investigates the shifts of climate zones from a landscape perspective on the Arctic for the period 1940–2013. The results reveal that the reduction in area is often accompanied by the fragmentation of the spatial structure. In terms of percentage of landscape, the coverage of polar climate zone had undergone a rapid decrease from 1940 to 2013. Moreover, the polar climate has been facing an intensified fragmentation over the time 1940–2013. Further analysis shows that this fragmentation phenomenon can be attributed more to anthropogenic than natural forcing from 1940 to 2003, even though the change in patch density is not steady, by comparison of observations and simulation results. In addition, the fragmentation in the Arctic climate zone depends on the horizontal resolution of data. Although the fragmentation trends of observations at three spatial resolutions of 2°–0.5° are consistent, the magnitude of trends weakens as the spatial resolution decreases.

Host–microbiota interactions and responses to grass carp reovirus infection in Ctenopharyngodon idellus - Fanshu Xiao; Lanjie Liao; Qiaoqing Xu; Zhili He; Tiaoyi Xiao; Jianjun Wang; Jie Huang; Yuhe Yu; Bo Wu; Qingyun Yan (Environmental Microbiology, 2021)
Summary Gut microbiota could facilitate host to defense diseases, but fish–microbiota interactions during viral infection and the underlying mechanism are poorly understood. We examined interactions and responses of gut microbiota to grass carp reovirus (GCRV) infection in Ctenopharyngodon idellus , which is the most important aquaculture fish worldwide. We found that GCRV infection group with serious haemorrhagic symptoms (G7s) showed considerably different gut microbiota, especially with an abnormally high abundance of gram‐negative anaerobic Cetobacterium somerae . It also showed the lowest ( p p Cetobacterium and Acinetobacter . The results suggested that an expansion of C. somerae initiated by GCRV could aggravate host inflammatory reactions through the LPS‐related NLRs and TLRs pathways. This study advances our understanding of the interplay between fish immunity and gut microbiota challenged by viruses; it also sheds new insights for ecological defense of fish diseases with the help of gut microbiota.

The Arabidopsis KH-domain protein FLOWERING LOCUS Y delays flowering by upregulating FLOWERING LOCUS C family members - Guang-Yi Dai; Ding-Kang Chen; Yun-Peng Sun; Wei-Yi Liang; Yu Liu; Li-Qun Huang; Yong-Kang Li; Jia-Fan He; Nan Yao (Plant Cell Reports, 2020)

Correction to: Fluoxetine and Riluzole Mitigates Manganese-Induced Disruption of Glutamate Transporters and Excitotoxicity via Ephrin-A3/GLAST-GLT-1/Glu Signaling Pathway in Striatum of Mice - Zhipeng Qi; Xinxin Yang; Yanqi Sang; Yanan Liu; Jiashuo Li; Bin Xu; Wei Liu; Miao He; Zhaofa Xu; Yu Deng; Jinghai Zhu (Neurotoxicity Research, 2020)

Quantitative Determination of Glymphatic Flow Using Spectrophotofluorometry - Yu Zhang; Jian Song; Xu-Zhong He; Jian Xiong; Rong Xue; Jia-Hao Ge; Shi-Yu Lu; Die Hu; Guo-Xing Zhang; Guang-Yin Xu; Lin-Hui Wang (Neuroscience Bulletin, 2020)

Image-Forming Visual Basis of Empathy for Pain in Mice - Kai-Wen Geng; Rui Du; Na Wei; Chun-Li Li; Yan Wang; Wei Sun; Tao Chen; Dong-Yu Wei; Yang Yu; Ting He; Wen-Jun Luo; Rui-Rui Wang; et al. (Neuroscience Bulletin, 2020)

Synaptic Adaptation Contributes to Stimulus-Specific Adaptation in the Thalamic Reticular Nucleus - Yu-Ying Zhai; Ryszard Auksztulewicz; Pei-Run Song; Zhi-Hai Sun; Yu-Mei Gong; Xin-Yu Du; Jie He; Xiongjie Yu (Neuroscience Bulletin, 2020)

Astaxanthin alleviates gestational diabetes mellitus in mice through suppression of oxidative stress - Yangyang Chen; Jichun Tang; Yinghong Zhang; Juan Du; Yuanli Wang; Hui Yu; Yanling He (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

Coupled numerical simulation of a flexible barrier impacted by debris flow with boulders in front - L. Zhao; J. W. He; Z. X. Yu; Y. P. Liu; Z. H. Zhou; S. L. Chan (Landslides, 2020)

Unraveling neuroHIV in the Presence of Substance Use Disorders - Yu Lin; Johnny J. He; Roger Sorensen; Linda Chang (Journal of Neuroimmune Pharmacology, 2020)

The Responses of Maize Yield and Water Use to Growth Stage-Based Irrigation on the Loess Plateau in China - Ning Jin; Jianqiang He; Quanxiao Fang; Chao Chen; Qingfu Ren; Liang He; Ning Yao; Libing Song; Qiang Yu (International Journal of Plant Production, 2020)

Identification of progranulin as a novel diagnostic biomarker for early-onset sepsis in neonates - Kai-Di Yang; Yu He; Sa Xiao; Qing Ai; Jia-Lin Yu (European Journal of Clinical Microbiology & Infectious Diseases, 2020)

Competitive Adsorption and Mobility of Propiconazole and Difenoconazole on Five Different Soils - Feiyan Wang; Duantao Cao; Lihong Shi; Shuhong He; Xin Li; Hua Fang; Yunlong Yu (Bulletin of Environmental Contamination and Toxicology, 2020)

Analyzing adaptation strategies for maize production under future climate change in Guanzhong Plain, China - Qaisar Saddique; Huanjie Cai; Jiatun Xu; Ali Ajaz; Jianqiang He; Qiang Yu; Yunfei Wang; Hui Chen; Muhammad Imran Khan; De Li Liu; Liang He (Mitigation and Adaptation Strategies for Global Change, 2020)

Enhancement of chlortetracycline biodegradation with Trichoderma harzianum LJ245 and its spore-producing mutants using co-metabolism - Yanju Li; Yu Gong; Huiying Zhao; Jingang Gu; Zinuo Wang; Xuli He (Biodegradation, 2020)

Complete genome sequences of porcine circovirus-like virus P1 mutants with 163 amino acids in the capsid protein - Libin Wen; Zhengyu Yu; Jianping Xie; Kongwang He (Archives of Virology, 2020)

Flavonoids repress the production of antifungal 2, 4‐DAPG but potentially facilitate root colonization of the rhizobacterium Pseudomonas fluorescens - Xiao‐Quan Yu; Xu Yan; Meng‐Yuan Zhang; Li‐Qun Zhang; Yong‐Xing He (Environmental Microbiology, 2020)
Summary In the well‐known legume–rhizobia symbiosis, flavonoids released by legume roots induce expression of the Nod factors and trigger early plant responses involved in root nodulation. However, it remains largely unknown how the plant‐derived flavonoids influence the physiology of non‐symbiotic beneficial rhizobacteria. In this work, we demonstrated that the flavonoids apigenin and/or phloretin enhanced the swarming motility and production of cellulose and curli in Pseudomonas fluorescens 2P24, both traits of which are essential for root colonization. Using a label‐free quantitative proteomics approach, we showed that apigenin and phloretin significantly reduced the biosynthesis of the antifungal metabolite 2,4‐DAPG and further identified a novel flavonoid‐sensing TetR regulator PhlH, which was shown to modulate 2,4‐DAPG production by regulating the expression of 2,4‐DAPG hydrolase PhlG. Although having similar structures, apigenin and phloretin could also influence different physiological characteristics of P . fluorescens 2P24, with apigenin decreasing the biofilm formation and phloretin inducing expression of proteins involved in the denitrification and arginine fermentation processes. Taken together, our results suggest that plant‐derived flavonoids could be sensed by the TetR regulator PhlH in P . fluorescens 2P24 and acts as important signalling molecules that strengthen mutually beneficial interactions between plants and non‐symbiotic beneficial rhizobacteria.

Responses of plant biomass and yield component in rice, wheat, and maize to climatic warming: a meta-analysis - Xiaodi Liu; Quanhui Ma; Hongying Yu; Yibo Li; Li Zhou; Qijin He; Zhenzhu Xu; Guangsheng Zhou (Planta, 2020)

The effect of blastomere loss during frozen embryo transfer on the transcriptome of offspring’s umbilical cord blood - Yan-Ting Wu; Ze-Han Dong; Cheng Li; Dai-Zhan Zhou; Jun-Yu Zhang; Yan Wu; Jing-Jing Xu; Yu Wang; Xiao-Qun Ye; Jian-Zhong Sheng; Li Wang; He-Feng Huang (Molecular Biology Reports, 2020)

Design and synthesis of novel spirooxindole–indenoquinoxaline derivatives as novel tryptophanyl-tRNA synthetase inhibitors - Wen Ren; Qian Zhao; Meng Yu; Li Guo; Hongmei Chang; Xian Jiang; Youfu Luo; Wei Huang; Gu He (Molecular Diversity, 2020)

Noise suppression–guided image filtering for low-SNR CT reconstruction - Yuanwei He; Li Zeng; Wei Yu; Changcheng Gong (Medical & Biological Engineering & Computing, 2020)

Effects of monsoon onset vortex on heat budget in the mixed layer of the Bay of Bengal - Kang Xu; Boqi Liu; Yu Liu; Weiqiang Wang; Zhuoqi He (Journal of Oceanology and Limnology, 2020)

Body weight, CYP2C19, and P2Y12 receptor polymorphisms relate to clopidogrel resistance in a cohort of Chinese ischemic stroke patients with aspirin intolerance - Zhiqiang Li; Wanqing Dong; Daorong Yang; Linhai Sun; Xianjun He; Huanhuan Hu; Jianping Zhang; Chunyu Wang; Yulin Li; Ming Zhao; Yu Kong; Yan Wang (European Journal of Clinical Pharmacology, 2020)

Unitary and binary remediations by plant and microorganism on refining oil-contaminated soil - Jia Jia Fei; Yun Yang Wan; Xin Yue He; Zhi Huan Zhang; Yu Xi Ying (Environmental Science and Pollution Research, 2020)

Differential distribution of and similar biochemical responses to different species of arsenic and antimony in Vetiveria zizanioides - Huang Yu; Xizhe Yan; Xiafei Zheng; Kui Xu; Qiuping Zhong; Tony Yang; Feifei Liu; Cheng Wang; Longfei Shu; Zhili He; Fanshu Xiao; Qingyun Yan (Environmental Geochemistry and Health, 2020)

Identification and Characterization of the Nuclease Activity of the Extracellular Proteins from Salmonella enterica Serovar Typhimurium - Chengshui Liao; Mengke Zhang; Xiangchao Cheng; Qi Li; Fuchao Mao; Xiaoli Wang; Chuan Yu; Zuhua Yu; Yanyan Jia; Jing Li; Lei He; Chunjie Zhang; et al. (Current Microbiology, 2020)

Is Disposal of Unused Pharmaceuticals as Municipal Solid Waste by Landfilling a Good Option? A Case Study in China - Qingwei Bu; Hongmei Cao; Xiaofan He; Handan Zhang; Gang Yu (Bulletin of Environmental Contamination and Toxicology, 2020)

Study on crack propagation and shear behavior of weak muddy intercalations submitted to wetting-drying cycles - L. P. He; J. Y. Yu; Q. J. Hu; Q. J. Cai; M. F. Qu; T. J. He (Bulletin of Engineering Geology and the Environment, 2020)

Energy geopolitics in Central Asia: China’s involvement and responses - Qiang Zhou; Ze He; Yu Yang (Journal of Geographical Sciences, 2020)

Evolutionary investment network and the emerging energy power in Central Asia: From the perspective of cross-border mergers and acquisitions - Ze He; Zhaohui Chong; Yu Yang; Yannan Zhou; Yi Liu (Journal of Geographical Sciences, 2020)

Dynamic transition mechanism analysis of the impact of energy development on urbanization in Central Asia - Yannan Zhou; Yu Yang; Zhouying Song; Ze He; Siyou Xia; Yawen Ren (Journal of Geographical Sciences, 2020)

Contrastive Studies of Cytarabine/Daunorubicin Dual-Loaded Liposomes Prepared by pH Gradient and Cu2+ Gradient Method - Jiaoyang Zhang; Lingli Zhou; Yu Zhang; Haibing He; Tian Yin; Jingxin Gou; Yanjiao Wang; Xing Tang (AAPS PharmSciTech, 2020)

Development and current state of seawater shrimp farming, with an emphasis on integrated multi‐trophic pond aquaculture farms, in China – a review - Zhi‐Qiang Chang; Amir Neori; Yu‐Ying He; Ji‐Tao Li; Ling Qiao; Steven Ian Preston; Ping Liu; Jian Li (Reviews in Aquaculture, 2020)
Shrimp farming has been the fastest‐growing sector in seawater aquaculture and has contributed to improving the farmers income and the utilization efficiency of aquaculture resources in China. The shrimp industry has deployed ever‐improved and innovated methods, from extensive farming to semi‐intensive and intensive farming. Various high‐density intensive culture models, such as high‐land, greenhouse and indoor industrialized culture models, have been used for shrimp pond farming in the coastal area. However, efficiency, environmental and social considerations have led to an increasing adoption of the environmentally‐friendly culture model called integrated multi‐trophic aquaculture (IMTA). This has occurred most rapidly along the northern and central coasts of China. The deployed IMTA culture models reviewed here are shrimp + crab, shrimp + fish, shrimp + sea cucumber, shrimp + jellyfish + clam, shrimp + crab + clam, shrimp + crab + clam + fish and the ridgetail white shrimp polyculture in saline alkaline water, which have been tailored to local conditions and organisms' characteristics. Suitable organism varieties and the maintenance of suitable eco‐friendly water quality have been key to success. The eco‐friendly IMTA culture models described here fully exploit the pond culture resources, to increase production with minimal additional feed and labor inputs, while reducing effluent emissions and treatment cost. The performance of shrimp IMTA models is compared to shrimp monoculture models regarding the economics. An equally important outcome of this publication is making generally accessible the findings from a vast Chinese scientific literature on shrimp culture that has hitherto been unavailable in English.