The transition from Palaeo-Asian to marginal Pacific tectonic domain experienced in the Eastern North China Craton: evidence from Late Jurassic sediment provenance in the North Yellow Sea Basin - Haitian Yu; Zhongjie Xu; Rihui Cheng; Duo Wan; Dan Gao; Zhen Zhang (Earth Science Informatics, 2022)

Beauty affects fairness: facial attractiveness alters neural responses to unfairness in the ultimatum game - Yu Pan; Jia Jin; Yan Wan; Yujia Wu; Fenghua wang; Sihua Xu; Lian Zhu; Jing Xu; Hengyi Rao (Brain Imaging and Behavior, 2022)

Failure criteria of unreinforced masonry walls of rural buildings under the impact of flash floods in mountainous regions - Guang-wu Si; Xiao-qing Chen; Jian-gang Chen; Wan-yu Zhao; Shuai Li; Xiang-ning Li (Journal of Mountain Science, 2022)

Measurement of surface deformation related to the December 2018 Mt. Etna eruption using time-series interferometry and magma modeling for hazard zone mapping - Suci Ramayanti; Arief R. Achmad; Hahn Chul Jung; Min-Jeong Jo; Sang-Wan Kim; Yu-Chul Park; Chang-Wook Lee (Geosciences Journal, 2022)

Effect of water temperature on embryonic development of Protunus trituberculatus in an off-season breeding mode - Jie He; Litao Wan; Huaihua Yu; Yingying Peng; Dongxu Zhang; Wenjun Xu (Frontiers in Marine Science, 2022)
Portunus trituberculatus (swimming crab) is an important breeding crab in China. The current breeding mode of swimming crab is still the traditional “spring seedling and winter harvest” breeding mode. In recent years, researchers have begun to explore a new off-season breeding mode through autumn seedling. In this study, the rate of embryonic development, embryo antioxidant ability and hatching rate of swimming crab in different water temperatures in an off-season breeding mode (breeding in early autumn) and digestive enzyme activity of newly hatched larvae were compared. The results showed that the duration of each development stage of swimming crab embryos was gradually reduced with increasing water temperature. The total development time was 9.43 d at 27°C and only 6.88 d at 33°C. These effects were accompanied by an increase in the development rate from 0.11 d -1 to 0.15 d -1 . The total effective accumulated temperature under the 4 temperature conditions was basically maintained at about 150°C·d (147.08 ∼ 153.62°C·d), and there was no significant difference between different groups. The development of embryos at 27°C and 29°C was very synchronous, and no abnormal embryos were observed. Conversely, at 31°C, the later stage of development exhibited asynchrony, and diapause and death were noted in some embryos. At 33°C, more embryos died. The embryo hatching rate was approximately 70% at 27°C and 29°C, and the rate was significantly reduced at 31°C and 33°C. Specifically, the rate was only 13.89% at 33°C. As the water temperature increased, the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) as well as the total antioxidant capacity (T-AOC) and malondialdehyde (MDA) levels of embryos increased first and then decreased, reaching the highest value at 31°C. Catalase (CAT) activity exhibited the opposite trend which was the lowest at 29 °C with a value of only 0.17 U/mg prot and the highest at 33°C with a value of up to 0.51 U/mg prot. At temperatures of 27°C, 29°C and 31°C, the differences in various digestive enzymes of newly hatched larvae primarily manifested as the high activities of pepsin (PEP) and α-amylase (AMS) at 31°C, and other differences were not obvious. At 33°C during embryonic development, the activities of various digestive enzymes were relatively low, especially the activities of trypsin (TPS) and cellulase (CL), which were significantly lower than those of the other three temperature groups. Therefore, judging from the antioxidant index of embryos and the digestive enzyme activity of newly hatched larvae, the embryonic development was still good when the water temperature was 31°C, accompanied by water temperatures above 31°C that seriously affected enzyme activity. Overall, a temperature below 31°C represents the appropriate temperature for embryonic development in autumn in swimming crabs.

Trimethylamine N-oxide facilitates the progression of atrial fibrillation in rats with type 2 diabetes by aggravating cardiac inflammation and connexin remodeling - Wan-Ying Jiang; Jun-Yu Huo; Sheng-Chan Wang; Yan-Di Cheng; Yi-Ting Lyu; Zhi-Xin Jiang; Qi-Jun Shan (Journal of Physiology and Biochemistry, 2022)

The carbon reduction effect of China’s outward foreign direct investment for carbon neutrality target - Zong-bin Zhang; Wan-yi Dong; Zi-yu Tang (Environmental Science and Pollution Research, 2022)

Adsorption/desorption of naphthalene and phenanthrene in a binary competitive system in the riparian zone - Weihong Dong; Xiaofang Shen; Yuyu Wan; Zhipeng Cao; Yujie Wei; Yu Liu (Environmental Geochemistry and Health, 2022)

mTORC1/C2 regulate spermatogenesis in Eriocheir sinensis via alterations in the actin filament network and cell junctions - Zhen-Fang Li; Shuang-Li Hao; Lan-Min Wang; Hong-Yu Qi; Jia-Ming Wang; Fu-Qing Tan; Wan-Xi Yang (Cell and Tissue Research, 2022)

New taxonomic framework for Arthrodermataceae: a comprehensive analysis based on their phylogenetic reconstruction, divergence time estimation, phylogenetic split network, and phylogeography - Zhi-Yuan Zhang; Yu-Lian Ren; Xin Li; Wan-Hao Chen; Jian-Dong Liang; Yan-Feng Han; Zong-Qi Liang (Antonie van Leeuwenhoek, 2022)

Associations of metal profiles in blood with thyroiditis: a cross-sectional study - Yaosheng Luo; Huixian Zeng; Yanshi Ye; Genfeng Yu; Cheng Song; Siyang Liu; Xingying Chen; Yuqi Jiang; Hualin Duan; Yue Li; Shengqing He; Zhi Chen; et al. (Environmental Science and Pollution Research, 2022)
Autoimmune thyroiditis (AIT) is increasingly common, and serological markers include thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TgAb). To determine if selected metals influence thyroiditis antibody positivity, this cross-sectional study investigated associations between metals and thyroiditis antibody status. Healthy individuals ( n = 1104) completed a questionnaire and underwent checkups of anthropometric parameters, thyroid function status, and levels of seven metals in blood (magnesium, iron, calcium, copper, zinc, manganese, and lead). Associated profiles of glyco- and lipid metabolism were also established. Logistic regression and restricted cubic spline (RCS) regression analysis were applied to adjudge associations between metals and TPOAb and TgAb status. It was found that, after adjusting for likely cofounding factors, participants with antibody positivity had significantly lower serum concentrations of magnesium and iron. When serum magnesium levels were analyzed in quartiles, the odds ratios of quartile 4 were 0.329–fold (95% confidence interval (CI): 0.167–0647) and 0.259-fold (95% CI 0.177–0.574) that of quartile 1 regarding TPOAb and TgAb positivity ( P = 0.004, 0.003). After adjustment, the RCS analysis detected nonlinear associations between iron and TPOAb and TgAb positivity ( P < 0.01, both). In stratified analyses, these associations regarding magnesium and iron remained for women of reproductive age, but not for postmenopausal women and men. We conclude that lower serum levels of magnesium and iron are associated with incremental positivity of thyroiditis antibodies and may be among the most important metals contributing to AIT in women of reproductive age.

A new triarylindanone and a new isobenzofuranone derivative from Selaginella tamariscina - Yu-Jie Peng; Dan Zhang; Wan-Ling Chen; Si-Yi Wang; Yao Zhang; Hui Zou; Hong-Ling Xiang; Ge-Lei Xiao (Natural Product Research, 2022)

Phylogenetic relationships and migration patterns of the Fargesia spathacea complex inferred from genomic data - Wan-Wan Li; Yun Zhou; Lei Huang; Yu‐Qu Zhang; Yi Ren; Jia-Ning Yu (Plant Systematics and Evolution, 2022)

A Population Pharmacokinetic Modelling Approach to Unravel the Complex Pharmacokinetics of Vincristine in Children - A. Laura Nijstad; Wan-Yu Chu; Evelien de Vos-Kerkhof; Catherine F. Enters-Weijnen; Mirjam E. van de Velde; Gertjan J. L. Kaspers; Shelby Barnett; Gareth J. Veal; Arief Lalmohamed; C. Michel Zwaan; Alwin D. R. Huitema (Pharmaceutical Research, 2022)
Background Vincristine, a chemotherapeutic agent that extensively binds to β-tubulin, is commonly dosed at 1.4–2.0 mg/m 2 capped at 2 mg. For infants, doses vary from 0.025–0.05 mg/kg or 50–80% of the mg/m 2 dose. However, evidence for lower doses in infants compared to older children is lacking. This study was conducted to unravel the complex pharmacokinetics of vincristine, including the effects of age, to assist optimal dosing in this population. Methods 206 patients (0.04–33.9 years; 25 patients < 1 years), receiving vincristine, with 1297 plasma concentrations were included. Semi-mechanistic population pharmacokinetic analyses were performed using non-linear mixed effects modelling. Results A three-compartment model, with one saturable compartment resembling saturable binding to β-tubulin and thus, saturable distribution, best described vincristine pharmacokinetics. Body weight and age were covariates significantly influencing the maximal binding capacity to β-tubulin, which increased with increasing body weight and decreased with increasing age. Vincristine clearance (CL) was estimated as 30.6 L/h (95% confidence interval (CI) 27.6–33.0), intercompartmental CL (Q) as 63.2 L/h (95%CI 57.2–70.1), volume of distribution of the central compartment as 5.39 L (95%CI 4.23–6.46) and of the peripheral compartment as 400 L (95%CI 357–463) (all parameters correspond to a patient of 70 kg). The maximal binding capacity was 0.525 mg (95%CI 0.479–0.602) (for an 18 year old patient of 70 kg), with a high association rate constant, fixed at 1300 /h and a dissociation constant of 11.5 /h. Interpretation A decrease of vincristine β-tubulin binding capacity with increasing age suggests that young children tolerate higher doses of vincristine.

Clinical profiles and antimicrobial resistance patterns of invasive Salmonella infections in children in China - Wen Song; Qingwen Shan; Yue Qiu; Xianyao Lin; Chunhui Zhu; Zhiqiang Zhuo; Caihong Wang; Jianning Tong; Rui Li; Chaomin Wan; Yu Zhu; Minxia Chen; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2022)
Invasive Salmonella infections result in a significant burden of disease including morbidity, mortality, and financial cost in many countries. Besides typhoid fever, the clinical impact of non-typhoid Salmonella infections is increasingly recognized with the improvement of laboratory detection capacity and techniques. A retrospective multicenter study was conducted to analyze the clinical profiles and antimicrobial resistance patterns of invasive Salmonella infections in hospitalized children in China during 2016–2018. A total of 130 children with invasive Salmonella infections were included with the median age of 12 months (range: 1–144 months). Seventy-nine percent of cases occurred between May and October. Pneumonia was the most common comorbidity in 33 (25.4%) patients. Meningitis and septic arthritis caused by nontyphoidal Salmonella (NTS) infections occurred in 12 (9.2%) patients and 5 (3.8%) patients. Patients < 12 months (OR: 16.04) and with septic shock (OR: 23.4), vomit (OR: 13.33), convulsion (OR: 15.86), C-reactive protein (CRP) ≥ 40 g/L (OR: 5.56), and a higher level of procalcitonin (PCT) (OR: 1.05) on admission were statistically associated to an increased risk of developing meningitis. Compared to 114 patients with NTS infections , 16 patients with typhoid fever presented with higher levels of CRP and PCT ( P < 0.05). The rates of resistance to ampicillin, sulfamethoxazole/trimethoprim, ciprofloxacin, and ceftriaxone among Salmonella Typhi and NTS isolates were 50% vs 57.3%, 9.1% vs 24.8%, 0% vs 11.2%, and 0% vs 9.9%, respectively. NTS has been the major cause of invasive Salmonella infections in Chinese children and can result in severe diseases. Antimicrobial resistance among NTS was more common.

Paroxysmal sympathetic hyperactivity: the storm after acute basilar artery occlusion - Juntao Yin; Wan Wang; Yu Wang; Yuqing Wei (Acta Neurologica Belgica, 2022)

At what size do anti-injury shelters start to play a positive role in the culture of Portunus trituberculatus? - Jie He; Huaihua Yu; Litao Wan; Dongxu Zhang; Wenjun Xu (Frontiers in Marine Science, 2022)
Based on the existing research, special plastic baskets were used as anti-injury shelters to explore the hidden behavior and molting growth of Portunus trituberculatus (Swimming crab) different initial body weights (Group A: 5.74 ± 0.11 g, Group B: 12.06 ± 0.15 g, Group C: 24.82 ± 0.41 g, Group D: 49.55 ± 1.12 g and Group E: 94.32 ± 1.19 g). The results showed that the shelter occupancy rate (SOR) during the daytime with all different body weights were significantly higher than that at night ( P < 0.05), and the SOR was proportional to the crab’s body weight, among them, SOR in group E was as high as 71.52%. Meanwhile, the territorial consciousness of smaller body weight crabs (Groups A, B and C) was poor, and there was a phenomenon in which multiple individuals occupied the same shelter at the same time, while the individuals with the body weight of approximately 50 g and above (Groups D and E) had strong territorial consciousness, and most of them occupied one shelter alone. In all groups, more individuals chose to molt in the shelter on condition that there existed shelter, and the rate of molting in group B was high up to 81.15% and that in other groups was about 60%. Although the existence of shelter had no significant influence on the molting interphase (MI) of swimming crab in each group, the body weight growth rate (WGR) and carapace width growth rate (WGR C ) after molting were increased by shelter compared with those without shelter. In addition, shelter could improve the survival rate (SR) in each group, and the effect of shelter on individuals with large body weight was relatively more obvious, in which the SR in Group D was significantly improved ( P < 0.05). In general, the shelter can play a positive role in the whole growth of swimming crab. Therefore, it is necessary to set up the shelter in advance before the seedlings are put into production, which is helpful to increase the yield of swimming crab.

The Rhizosphere Microbial Index Reflects the Optimal Restoration Pattern and the Nutrient Preference of Rhizosphere Microbes of Typical Plants in a Desertified Environment - Boyuan Bi; Chuanyu Wan; Qian Tong; Kun Wang; He Zhang; Yu Wang; Fengpeng Han (Journal of Soil Science and Plant Nutrition, 2022)

Dissecting the role of cell signaling versus CD8+ T cell modulation in propranolol antitumor activity - Wei Li; Jielin Wan; Cuiyu Chen; Chengfang Zhou; Ping Liao; Qian Hu; Jiali Hu; Yang Wang; Yu Zhang; Cong Peng; Yuanfei Huang; Weihua Huang; et al. (Journal of Molecular Medicine, 2022)

The Effect of Co-Exposure to Glyphosate, Cadmium, and Arsenic on Chronic Kidney Disease - Junne-Ming Sung; Wei-Hsiang Chang; Kuan-Hung Liu; Chung Yu Chen; Trias Mahmudiono; Wan-Ru Wang; Ho-Chi Hsu; Zhen-Yi Li; Hsiu-Ling Chen (Exposure and Health, 2022)

Catalytic effect of cesium on the oxidation behavior of cation exchange resins in Li2CO3-Na2CO3-K2CO3 melt - Yang-Hai Zheng; Yong-De Yan; Yun Xue; Yue-Lin Wang; Xin Liu; Wan-Sheng Mi; Qing-Guo Zhang; Yu Li; Fu-Qiu Ma; Mi-Lin Zhang; Zhi-Hao Gan; Kai Zhu (Environmental Science and Pollution Research, 2022)

Effects of soil organic matter components and iron aluminum oxides on aggregate stability during vegetation succession in granite red soil eroded areas - Zhe Lin; Zhi-gang Huang; Da-lan Liao; Wan-xia Huang; Juan Huang; Yu-song Deng (Journal of Mountain Science, 2022)

Effects of testosterone on skin structure and factors related to androgen conversion and binding in Hetian sheep - Ruijun Shi; Shuwei Li; Penggang Liu; Lili Guo; Shujuan Gong; Yu Wan (Tropical Animal Health and Production, 2022)

The Effects of Diameter, Length and Insertion Method on the Stability of Orthodontic Miniscrew - Wan-Ping Yu; Jian-Hong Yu; Shiuan-Hui Wang; Jui-Ting Hsu (Journal of Medical and Biological Engineering, 2022)

The safety degree evaluation of marine biodiversity in China - Xiu-Mei Fu; Wan-Yu Wu; Fang Yang; Shan-Shan Jiang; Shi-Qi Wang; Xiao-Yan Li; Hui-Ying Tang; Ying Liu; Chang-Yun Wang (Journal of Coastal Conservation, 2022)

Pollution assessment, source identification, and health risks of heavy metals: a case study in a typical wheat–maize rotation area of eastern China - Fang Wan; Yongbo Teng; Xiuwen Zhang; Linsong Yu; Hong Pan; Hui Wang; Quangang Yang; Yanhong Lou; Yuping Zhuge (Environmental Geochemistry and Health, 2022)

Plant secondary metabolite and temperature determine the prevalence of Arsenophonus endosymbionts in aphid populations - Chun‐Yan Chang; Xiao‐Wan Sun; Pan‐Pan Tian; Ning‐Hui Miao; Yu‐Lin Zhang; Xiang‐Dong Liu (Environmental Microbiology, 2022)
Summary Transmission rate and role in hosts contribute to the prevalence of an endosymbiont. However, factors affecting transmission and role of facultative endosymbionts are still not well understood. Here, we illustrated that host plants and environmental temperatures affected the transmission, relative abundance and role of Arsenophonus in the cotton aphid Aphis gossypii . The transmission rate of this endosymbiont from mother aphids to offspring was relatively lower. High temperatures impeded the transmission, and infection rates declined as aphids were exposed to 30°C. Contents of amino acids and secondary metabolites were remarkably different among host plants. Aphids feeding on zucchini leaves containing a higher titre of amino acids and lower secondary metabolites harboured a relatively lower abundance of Arsenophonus . Concentrations of an amino acid and a plant secondary metabolite, cucurbitacin B, in aphid diet were not associated with Arsenophonus abundance. However, gossypol, another plant secondary metabolite, was strongly related with the abundance. Arsenophonus imparted a fitness benefit to aphids, and the benefit was dependent on host plants and gossypol concentration. In sum, plant secondary metabolite and environmental temperature affect transmission, relative abundance and role of Arsenophonus , which determine the endosymbiont prevalence in aphid populations.

Fissistiganoids A and B: two new flavonoids from the Fissistigma tungfangense - Wan-Lin Zhong; Xue-Ming Zhou; Ji-Ling Yi; Xin-Ming Song; Bin Zhang; Jing-Yu Yang; Guang-Ying Chen (Natural Product Research, 2022)

Comparing the Muscle Nutritional Quality of Eight Common Wild-Caught Economic Shrimp Species from the East China Sea - Litao Wan; Yingying Peng; Huaihua Yu; Wenjun Xu; Jie He (Journal of Aquatic Food Product Technology, 2022)

Recent advances in RNA structurome - Bingbing Xu; Yanda Zhu; Changchang Cao; Hao Chen; Qiongli Jin; Guangnan Li; Junfeng Ma; Siwy Ling Yang; Jieyu Zhao; Jianghui Zhu; Yiliang Ding; Xianyang Fang; et al. (Science China Life Sciences, 2022)

Identifying factors contributing to social vulnerability through a deliberative Q-Sort process: an application to heat vulnerability in Taiwan - Leslie Mabon; Wan-Yu Shih (Natural Hazards, 2022)
Extreme heat events are gaining ever more policy and societal attention under a warming climate. Although a breadth of expertises are required to understand drivers of vulnerability to hazards such as extreme heat, it is also acknowledged that expert assessments in group settings may be subject to biases and uneven power relations. In this Technical Note, we outline a structured deliberative process for supporting experts to work collaboratively to assess social vulnerability to a climate-related hazard, in this case extreme heat in Taiwanese cities. We argue that adapting elicitation approaches such as Q-Methodology for use in collaborative settings can help to organise expert discussion and enable dialogue and mutual learning, in a way that supports consensus-building on vulnerability assessment. Outcomes from our collaborative assessments suggest elderly people living alone, elderly people over 75, pre-existing circulatory diseases and level of participation in community decision-making may all be notable drivers of heat vulnerability in the Taiwanese context. Methodologically, we argue that collaborative sorting exercises offer a way to embed local and experiential knowledges into assessments of available evidence, but that strong facilitation and additional checks are necessary to ensure an inclusive process that reflects the diversity of perspectives involved.

Identification of the Largest SCA36 Pedigree in Asia: with Multimodel Neuroimaging Evaluation for the First Time - Yue Xie; Zhao Chen; Zhe Long; Rui-Ting Chen; Yi-Zheng Jiang; Ming-Jie Liu; Lin-Liu Peng; Hui-Rong Peng; Na Wan; Guangdong Zou; Chun-Rong Wang; Yu-Ting Shi; et al. (The Cerebellum, 2022)

The assessment and source apportionment of metals in the water-level fluctuation zone of the upper reaches Yangtze mainstream - Pengcheng Wang; Li Ma; Qiuyun Huang; Hai Yu; Ying Liu; Weiwei Jiang; Juan Wan; Qin Wang; Henglin Xiao (Journal of Soils and Sediments, 2022)

Comparison of Different Chemical Extraction Methods for Predicting the Bioavailability and Phytotoxicity of Soil PAEs to Green Vegetables (Brassica Rapa Var. Chinensis) - Jinjin Cheng; Xiaolong Chen; Lili Tian; Qun Wan; Xiangyang Yu (Bulletin of Environmental Contamination and Toxicology, 2022)

Mechanical damage evolution and mechanism of sandstone with prefabricated parallel double fissures under high-humidity condition - Wei Chen; Wen Wan; Yanlin Zhao; Huan He; Qiuhong Wu; Yu Zhou; Senlin Xie (Bulletin of Engineering Geology and the Environment, 2022)

Controlling average number of photons received per biomass to promote the growth of Synechocystis sp. PPC 6803 - Jiangong Zhang; Fei Fan; Tao Yu; Jianpei Chen; Minxi Wan; Yuanguang Li (Biotechnology Letters, 2022)

FLOURY AND SHRUNKEN ENDOSPERM6 Encodes a Glycosyltransferase and is Essential for the Development of Rice Endosperm - Hang Yang; Linglong Liu; Kai Wu; Shijia Liu; Xi Liu; Yunlu Tian; Yunlong Wang; Erchao Duan; Jie Lei; Xiuhao Bao; Rongbo Chen; Xiaoli Chen; et al. (Journal of Plant Biology, 2022)

Heavy metal spatial distribution, sources and ecological risks in farmland soils from three areas in the Yangtze River basin in Anhui - Kuan Zhao; Ruixin Hu; Xin Wan; Baohua Zhou; Yu Wang (Arabian Journal of Geosciences, 2022)

Influence of humidity on mechanical properties of fractured sandstone under the triaxial compression - Yu Zhou; Wen Wan; Huan He; Wei Chen; Yanlin Zhao; Qiuhong Wu; Senlin Xie (Arabian Journal of Geosciences, 2022)

Development of novel polymorphic microsatellite markers for Picea brachytyla - Shuai-Peng Si; Chun-Jing Wang; Ji-Zhong Wan; Yu-Lin Qian; Chun-Hui Zhang (Molecular Biology Reports, 2022)

Effects of Involuntary and Voluntary Exercise in Combination with Acousto-Optic Stimulation on Adult Neurogenesis in an Alzheimer's Mouse Model - Wan-yi Li; Jun-yan Gao; Su-Yang Lin; Shao-tao Pan; Biao Xiao; Yu-tao Ma; Kai Xie; Wei Shen; Zhi-tao Liu; Guang-yu Li; Jie-jie Guo; Qin-wen Wang; et al. (Molecular Neurobiology, 2022)

The Effects of Ground and Treadmill Running on Energy Metabolism and Muscle Contractile Properties: A Randomized Cross-Over Study - Yuan Zhou; Jian-gang Chen; Xiao-long Li; Xin-liang Pan; Yi-zheng Zhou; Zheng-ao Li; Zhi-cheng Liang; Jia-min Long; Ming-ze Qin; Jing Zhang; Bing Shi; Bing-jun Wan; et al. (Journal of Science in Sport and Exercise, 2022)
Purpose This study aimed to compare the effects of ground and treadmill running on energy metabolism and muscle contractile properties, providing a basis for the general public to choose running venues. Methods Ten male college students (age, 20.10 ± 1.53 years; height, 176.20 ± 5.49 cm; weight, 72.14 ± 8.25 kg; body fat percent, 12.41% ± 4.65%) were recruited in this study. Energy expenditure (EE) was measured using the accelerometer (GT9X) combined with specific estimation equations. Average heart rate (HR) was measured using a heart rate band (Polar). Muscle contractile properties were assessed by measuring muscle displacement (Dm) and contraction velocity (Vc) using tensiomyography (TMG-S1). Blood glucose (Glu) and lactate (Lac) were measured by portable devices (eB-G and Lactate Scout). The running speed was 9 km/h and the duration was 25 min. Two-way ANOVA (protocol × time) was used to analyze the effect of running protocols on energy metabolism and muscle contractile properties. Results EE of treadmill running was significantly higher than EE of ground running (protocol main effect, P < 0.001), and HR of treadmill running was significantly higher than that of ground running in the first testing time (protocol simple effect, P = 0.026; protocol × time interaction P = 0.043). The decrease in Dm of the rectus femoris after treadmill running was significantly higher than that of ground running (protocol main effect, P = 0.009). The interaction of different running protocols and testing times on Lac was significant ( P = 0.025), but all results of the simple effects analysis were not statistically significant ( P > 0.05). Conclusion Our study found a difference in energy expenditure between treadmill and ground running at 9 km/h with duration of 25 min. In addition, treadmills are more likely to cause a decrease in muscle displacement distance of the rectus femoris measured after exercise than ground running. Future studies are needed to further investigate whether the differences are induced by internal metabolism or the environmental conditions of running.

Stable Isotopes Reveal Water Vapor Sources of Precipitation over the Jiaolai Plain, Shandong Peninsula, China - Ying Wang; Bu-li Cui; Dong-sheng Li; Ya-xuan Wang; Wan-xin Yu; He-hua Zong (Asia-Pacific Journal of Atmospheric Sciences, 2022)

Anterior Cingulate Cortex Mediates Hyperalgesia and Anxiety Induced by Chronic Pancreatitis in Rats - Dan Ren; Jia-Ni Li; Xin-Tong Qiu; Fa-Ping Wan; Zhen-Yu Wu; Bo-Yuan Fan; Ming-Ming Zhang; Tao Chen; Hui Li; Yang Bai; Yun-Qing Li (Neuroscience Bulletin, 2022)
Central sensitization is essential in maintaining chronic pain induced by chronic pancreatitis (CP), but cortical modulation of painful CP remains elusive. Here, we examined the role of the anterior cingulate cortex (ACC) in the pathogenesis of abdominal hyperalgesia in a rat model of CP induced by intraductal administration of trinitrobenzene sulfonic acid (TNBS). TNBS treatment resulted in long-term abdominal hyperalgesia and anxiety in rats. Morphological data indicated that painful CP induced a significant increase in FOS-expressing neurons in the nucleus tractus solitarii (NTS) and ACC, and some FOS-expressing neurons in the NTS projected to the ACC. In addition, a larger portion of ascending fibers from the NTS innervated pyramidal neurons, the neural subpopulation primarily expressing FOS under the condition of painful CP, rather than GABAergic neurons within the ACC. CP rats showed increased expression of vesicular glutamate transporter 1, and increased membrane trafficking and phosphorylation of the N -methyl-D-aspartate receptor (NMDAR) subunit NR2B and the α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) subunit GluR1 within the ACC. Microinjection of NMDAR and AMPAR antagonists into the ACC to block excitatory synaptic transmission significantly attenuated abdominal hyperalgesia in CP rats, which was similar to the analgesic effect of endomorphins injected into the ACC. Specifically inhibiting the excitability of ACC pyramidal cells via chemogenetics reduced both hyperalgesia and comorbid anxiety, whereas activating these neurons via optogenetics failed to aggravate hyperalgesia and anxiety in CP rats. Taken together, these findings provide neurocircuit, biochemical, and behavioral evidence for involvement of the ACC in hyperalgesia and anxiety in CP rats, as well as novel insights into the cortical modulation of painful CP, and highlights the ACC as a potential target for neuromodulatory interventions in the treatment of painful CP.

Uptake, translocation, and subcellular distribution of three triazole pesticides in rice - Haocong Li; Yong Li; Wenfeng Wang; Qun Wan; Xiangyang Yu; Wenjing Sun (Environmental Science and Pollution Research, 2022)

Interaction between organic matter and tetracycline in river sediments in cold regions - Changyong Wu; Rui Tang; Huiqi Li; Xiang Liu; Liya Fu; Yin Yu; Chunli Wan (Environmental Science and Pollution Research, 2022)

Stability properties of natural estrogen conjugates in different aqueous samples at room temperature and tips for sample storage - Jun Zhang; Yi-ping Wan; Ze-hua Liu; Hao Wang; Zhi Dang; Yu Liu (Environmental Science and Pollution Research, 2022)

Effects of different stocking densities on the growth performance and antioxidant capacity of Chinese mitten crab (Eriocheir sinensis) in rice crab culture system - Xin Wang; Qi Yao; Xin-yu Lei; Dong-ming Zhang; Sen Wang; Ji-wu Wan; Hong-jian Liu; Yu-ke Chen; Yun-long Zhao; Gui-qin Wang; Qiu-ju Wang; Zhi-xin Guo (Aquaculture International, 2022)

Hippocampal SIRT1-Mediated Synaptic Plasticity and Glutamatergic Neuronal Excitability Are Involved in Prolonged Cognitive Dysfunction of Neonatal Rats Exposed to Propofol - Lin-Hui Ma; Jie Wan; Jing Yan; Ning Wang; Yan-Ping Liu; Hai-Bi Wang; Cheng-Hua Zhou; Yu-Qing Wu (Molecular Neurobiology, 2022)

Sesquiterpene lactones isolated from Carpesium abrotanoides L. by LC–MS combined with HSCCC inhibit liver cancer through suppression of the JAK2/STAT3 signaling pathway - Bingbing Shen; Yupei Yang; Dan Wan; Huanghe Yu; Yuan Cai; Xionglong Wang; Daifeng Tang; Chunyu Tang; Shuihan Zhang (Medicinal Chemistry Research, 2022)

Another Record: Ocean Warming Continues through 2021 despite La Niña Conditions - Lijing Cheng; John Abraham; Kevin E. Trenberth; John Fasullo; Tim Boyer; Michael E. Mann; Jiang Zhu; Fan Wang; Ricardo Locarnini; Yuanlong Li; Bin Zhang; Zhetao Tan; et al. (Advances in Atmospheric Sciences, 2022)
The increased concentration of greenhouse gases in the atmosphere from human activities traps heat within the climate system and increases ocean heat content (OHC). Here, we provide the first analysis of recent OHC changes through 2021 from two international groups. The world ocean, in 2021, was the hottest ever recorded by humans, and the 2021 annual OHC value is even higher than last year’s record value by 14 ± 11 ZJ (1 zetta J = 10 21 J) using the IAP/CAS dataset and by 16 ± 10 ZJ using NCEI/NOAA dataset. The long-term ocean warming is larger in the Atlantic and Southern Oceans than in other regions and is mainly attributed, via climate model simulations, to an increase in anthropogenic greenhouse gas concentrations. The year-to-year variation of OHC is primarily tied to the El Niño-Southern Oscillation (ENSO). In the seven maritime domains of the Indian, Tropical Atlantic, North Atlantic, Northwest Pacific, North Pacific, Southern oceans, and the Mediterranean Sea, robust warming is observed but with distinct inter-annual to decadal variability. Four out of seven domains showed record-high heat content in 2021. The anomalous global and regional ocean warming established in this study should be incorporated into climate risk assessments, adaptation, and mitigation.

Comparison of nominal and standardized catch per unit effort data in quantifying habitat suitability of skipjack tuna in the equatorial Pacific Ocean - Cheng Zhou; Yuanyuan Hu; Jie Cao; Liuxiong Xu; Xuefang Wang; Rong Wan; Yu Xiao; Jiangfeng Zhu; Hao Tang (Acta Oceanologica Sinica, 2022)

Evolution of a primary consumer in response to low and high food availability shapes life history traits and population demography - Quan Wan; Zhi-Yu Huang; Kun Zhang; Yi-Long Xi (Hydrobiologia, 2022)

Detection of pulmonary tuberculosis in children using the Xpert MTB/RIF Ultra assay on sputum: a multicenter study - Xiaoshan Peng; Qiong Liao; Min Fang; Yu Zhu; Yan Shi; Shuting Quan; Yacui Wang; Li Duan; Xiaomei Shi; Yang Liu; Manzhi Wang; Qingsong Wei; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2022)

Serine protease HtrA2/Omi regulates adaptive mitochondrial reprogramming in the brain cortex after ischemia/reperfusion injury via UCP2-SIRT3-PGC1 axis - Hao Meng; Lian-Kun Sun; Jing Su; Wan-Yu Yan; Yao Jin; Xin Luo; Xian-Rui Jiang; Hong-Lei Wang (Human Cell, 2022)

Astragalus Polysaccharide Protects Against Cadmium-Induced Autophagy Injury Through Reactive Oxygen Species (ROS) Pathway in Chicken Embryo Fibroblast - Xudong Shen; Zequn Tang; Yu Bai; Meishuo Wan; Miao Yu; Jingyi Chen; Guangxing Li; Ruili Zhang; Ming Ge (Biological Trace Element Research, 2022)

Expression pattern of alkB homolog 5 in goat testis and its role in spermatogonial stem cells - Zifei Liu; Yu Cai; Mingtian Deng; Dongxu Li; Qingqing Leng; Liangyue Shi; Yutong Tang; Feng Wang; Yongjie Wan (Cell and Tissue Research, 2022)

The Effects of Limosilactobacillus reuteri LR-99 Supplementation on Body Mass Index, Social Communication, Fine Motor Function, and Gut Microbiome Composition in Individuals with Prader–Willi Syndrome: a Randomized Double-Blinded Placebo-Controlled Trial - Xue-Jun Kong; Kevin Liu; Patrick Zhuang; Ruiyi Tian; Siyu Liu; Cullen Clairmont; Xiaojing Lin; Hannah Sherman; Junli Zhu; Yelan Wang; Michelle Fong; Alice Li; et al. (Probiotics and Antimicrobial Proteins, 2021)
Prader–Willi syndrome (PWS) is a rare genetic disorder associated with developmental delay, obesity, and neuropsychiatric comorbidities. Limosilactobacillus reuteri ( Lactobacillus reuteri , Lact. reuteri ) has demonstrated anti-obesity and anti-inflammatory effects in previous studies. In the present study, we aim to evaluate the effects of Lact. reuteri supplementation on body mass index (BMI), social behaviors, and gut microbiota in individuals with PWS. We conducted a 12-week, randomized, double-blind, placebo-controlled trial in 71 individuals with PWS aged 6 to 264 months (64.4 ± 51.0 months). Participants were randomly assigned to either receive daily Lact. reuteri LR-99 probiotic (6 × 10 10 colony forming units) or a placebo sachet. Groupwise differences were assessed for BMI, ASQ-3, and GARS-3 at baseline, 6 weeks, and 12 weeks into treatment. Gut microbiome data was analyzed with the QIIME2 software package, and predictive functional profiling was conducted with PICRUSt-2. We found a significant reduction in BMI for the probiotic group at both 6 weeks and 12 weeks relative to the baseline ( P < 0.05). Furthermore, we observed a significant improvement in social communication and interaction, fine motor function, and total ASQ-3 score in the probiotics group compared to the placebo group ( P < 0.05). Altered gut microbiota was observed in the probiotic group to favor weight loss and improve gut health. The findings suggest a novel therapeutic potential for Lact. reuteri LR-99 probiotic to modulate BMI, social behaviors, and gut microbiota in Prader–Willi syndrome patients, although further investigation is warranted. Trial registration Chinese Clinical Trial Registry: ChiCTR1900022646

Different Changing Patterns of Three NOS–NO System Activities after Ischemia–Reperfusion in Rabbit with AMI - Jun Zhang; Chao Chen; Fengpeng Li; Guangren Gao; Jinguo Fu; Heping Niu; Kai Yu; Lei Wang; Run Guo; Yanfang Wan; Zhanfeng Ma; Qianyu Zhang; et al. (Cell Biochemistry and Biophysics, 2021)

Experimental study on capillary water rise and influencing factors in silty soil - Wangwen Huo; Zhiduo Zhu; Yuyi Peng; Shaoyun Pu; Yu Wan; Chen Zhang (Arabian Journal of Geosciences, 2021)

Application of GIS-based DRASTIC model approaches in assessing groundwater vulnerability for shallow alluvial aquifer deposited - Aida Soraya Shamsuddin; Sharifah Norkhadijah Syed Ismail; Emilia Zainal Abidin; Ho Yu Bin; Hafizan Juahir; Wan Azdie Mohd. Abu Bakar (Arabian Journal of Geosciences, 2021)

Three-Dimensional Heterogeneity of Cerebellar Interposed Nucleus-Recipient Zones in the Thalamic Nuclei - Kuang-Yi Ma; Xin-Yu Cai; Xin-Tai Wang; Zhao-Xiang Wang; Wan-Meng Huang; Zhi-Ying Wu; Zhou-Yan Feng; Ying Shen (Neuroscience Bulletin, 2021)

Emerging Benefits: Pathophysiological Functions and Target Drugs of the Sigma-1 Receptor in Neurodegenerative Diseases - Ning-hua Wu; Yu Ye; Bin-bin Wan; Yuan-dong Yu; Chao Liu; Qing-jie Chen (Molecular Neurobiology, 2021)

Exposure to 2,4-dichlorophenol, 2,4,6-trichlorophenol, pentachlorophenol and risk of thyroid cancer: a case-control study in China - Wan-Jun Yang; Hua-Bing Wu; Chi Zhang; Qi Zhong; Ming-Jun Hu; Jia-Liu He; Guo-Ao Li; Zhen-Yu Zhu; Jin-Liang Zhu; Huan-Huan Zhao; Han-Shuang Zhang; Fen Huang (Environmental Science and Pollution Research, 2021)

Directional arrangement of phyllite fragments in phyllite talus slope at the eastern margin of the Tibetan Plateau - Yu-hao Wan; Xiao-yan Zhao; Si-xiang Ling; Jin Li; Cai-yun Zeng; Wünnemann Bernd (Journal of Mountain Science, 2021)

Differential metabolism-associated gene expression of duck pancreatic cells in response to two strains of duck hepatitis A virus type 1 - Zhen Chen; Shao-hua Shi; Yu Huang; Cui-qin Huang; Rong-chang Liu; Long-fei Cheng; Guang-hua Fu; Hong-mei Chen; Chun-he Wan; Qiu-ling Fu (Archives of Virology, 2021)
Several outbreaks of duck hepatitis A virus type 1 (DHAV-1), which were characterized by yellow coloration and hemorrhage in pancreatic tissues, have occurred in China. The causative agent is called pancreatitis-associated DHAV-1. The mechanisms involved in pancreatitis-associated DHAV-1 infection are still unclear. Transcriptome analysis of duck pancreas infected with classical-type DHAV-1 and pancreatitis-associated DHAV-1 was carried out. Deep sequencing with Illumina-Solexa resulted in a total of 53.9 Gb of clean data from the cDNA library of the pancreas, and a total of 29,597 unigenes with an average length of 993.43 bp were generated by de novo sequence assembly. The expression levels of D-3-phosphoglycerate dehydrogenase, phosphoserine aminotransferase, and phosphoserine phosphatase, which are involved in glycine, serine, and threonine metabolism pathways, were significantly downregulated in ducks infected with pancreatitis-associated DHAV-1 compared with those infected with classical-type DHAV-1. These findings provide information regarding differences in expression levels of metabolism-associated genes between ducks infected with pancreatitis-associated DHAV-1 and those infected with classical-type DHAV-1, indicating that intensive metabolism disorders may contribute to the different phenotypes of DHAV-1-infection.

A Systematic Approach for Liposome and Lipodisk Preclinical Formulation Development by Microfluidic Technology - Elizabeth S. Levy; Jesse Yu; Alberto Estevez; Jialin Mao; Liling Liu; Elizabeth Torres; Dennis Leung; Chun-Wan Yen (The AAPS Journal, 2021)

The Decision Strategies of Adolescents with Different Emotional Stabilities in Unfair Situations - Yajing Si; Lin Jiang; Chanlin Yi; Qi Zhang; Cunbo Li; Jing Yu; Peiyang Li; Qiang Liu; Feng Wan; Fali Li; Dezhong Yao; Peng Xu (Neuroscience Bulletin, 2021)

Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1 - Guang-Tong Jiang; Lin Shao; Shuo Kong; Meng-Liu Zeng; Jing-Jing Cheng; Tao-Xiang Chen; Song Han; Jun Yin; Wan-Hong Liu; Xiao-Hua He; Yu-Min Liu; Lanzi Gongga; et al. (Neuroscience Bulletin, 2021)

Experimental study on the suffusion mechanism of gap-graded soils under an exceedance hydraulic gradient - Liang Chen; Yu Wan; Jian-Jian He; Chun-Mu Luo; Shu-Fa Yan; Xian-Feng He (Natural Hazards, 2021)

SETD3 Downregulation Mediates PTEN Upregulation-Induced Ischemic Neuronal Death Through Suppression of Actin Polymerization and Mitochondrial Function - Xiangyu Xu; Yu Cui; Congqin Li; Yuyang Wang; Jing Cheng; Songfeng Chen; Jiangdong Sun; Jinyang Ren; Xujin Yao; Jingchen Gao; Xiaohong Huang; Qi Wan; et al. (Molecular Neurobiology, 2021)

Inhibition of miR-1298-5p attenuates sepsis lung injury by targeting SOCS6 - Jian Ma; Li-Yun Xu; Qiu-Hong Sun; Xiao-Yu Wan; BingLi (Molecular and Cellular Biochemistry, 2021)

Ion migration process and influencing factors in inland river basin of arid area in China: a case study of Shiyang River Basin - Huiying Ma; Guofeng Zhu; Yu Zhang; Liyuan Sang; Qiaozhuo Wan; Zhiyuan Zhang; Yuanxiao Xu; Dongdong Qiu (Environmental Science and Pollution Research, 2021)

Analysis of the mechanism and failure mode of landslides subjected to transient seepage in a Piedmont region of Nanjing area - Liangchen Yu; Changhong Yan; Shulan Guo; Jinzhong Tan; Jianqiang Guo; Zhihui Lou; Jiajia Wan (Bulletin of Engineering Geology and the Environment, 2021)

Seismic gravelly soil liquefaction assessment based on dynamic penetration test using expanded case history dataset - Nima Pirhadi; Jilei Hu; Yu Fang; Idriss Jairi; Xusheng Wan; Jianguo Lu (Bulletin of Engineering Geology and the Environment, 2021)

Geniposide-Loaded Liposomes for Brain Targeting: Development, Evaluation, and In Vivo Studies - Jinyan Wan; Yu Long; Songyu Liu; Yulu Zhang; Yan Xiang; Dan Li; Ai Shi; Yu Shuang; Ying Li; Yanan He; Nan Li; Yongmei Guan (AAPS PharmSciTech, 2021)

Research progress in bioremediation of petroleum pollution - Yong Yang; Zhan-Wei Zhang; Rui-Xia Liu; Hai-Yan Ju; Xue-Ke Bian; Wan-Ze Zhang; Chuan-Bo Zhang; Ting Yang; Bing Guo; Chen-Lei Xiao; He Bai; Wen-Yu Lu (Environmental Science and Pollution Research, 2021)

Dynamic characteristics of chlorine dispersion process and quantitative risk assessment of pollution hazard - Baoquan Xin; Jianliang Yu; Wenyi Dang; Lu Wan (Environmental Science and Pollution Research, 2021)

Effects of soil shrinkage in permanent gullies formation: The case of Benggang erosion in the granite area of southern China - Wan-xia Huang; Yu-song Deng; Chong-fa Cai; Dai-hua Jiang (Journal of Mountain Science, 2021)

Spatiotemporal characteristics and trend assessment of Ms ≥ 5.6 earthquakes in the Tianshan area of China based on co-occurrence analysis and commensurability - Jia Wan; Jun-Ping Yan; Zi-Qiang Liu; Xiao-Meng Wang; Yu-Feng Zhang; Cheng-Bo Wang (Applied Geophysics, 2021)

First report of peanut foot rot caused by Fusarium neocosmosporiellum in Shandong Province, China - Manlin Xu; Xia Zhang; Zhiqing Guo; Jing Yu; Juxiang Wu; Xinguo Li; Yucheng Chi; Shubo Wan (Journal of Plant Pathology, 2021)

Establishment and characterization of the Bactrocera dorsalis (Diptera: Tephritidae) embryonic cell line QAU-Bd-E-2 - Gui-Ling Zheng; Jie Li; Qian-Long Yu; Bin Zhang; Xue-Meng Ding; Hui Li; Hong-Xu Zhou; Fang-Hao Wan; Chang-You Li (In Vitro Cellular & Developmental Biology - Animal, 2021)

Effects of Selenium on MAC-T Cells in Bovine Mastitis: Transcriptome Analysis of Exosomal mRNA Interactions - Hongyuan Jing; Yu Chen; Wan Liang; Miaoyu Chen; Changwei Qiu; Meng-yao Guo (Biological Trace Element Research, 2021)

Aristolochic acid IVa forms DNA adducts in vitro but is non-genotoxic in vivo - Jingjing Wan; Ruixue Chen; Zhou Yang; Jing Xi; Yiyi Cao; Yu Chen; Xinyu Zhang; Yang Luan (Archives of Toxicology, 2021)

An Analytical Method to Estimate Seabed Topography Only from Vertical Gravitational Gradient - Jinhai Yu; Huan Xu; Xiaoyun Wan (Marine Geodesy, 2021)

Prenylated xanthones and biphenyls from Garcinia esculenta with antistaphylococcal activity - Dan Zheng; Hong Zhang; Jia-Ming Jiang; Yu-Yu Chen; Shi-Jie Wan; Zhi-Xiu Lin; Hong-Xi Xu (Natural Product Research, 2021)

Congestive heart failure in COX2 deficient rats - Qiangyou Wan; Deping Kong; Qian Liu; Shumin Guo; Chenchen Wang; Yan Zhao; Zun-Ji Ke; Ying Yu (Science China Life Sciences, 2021)

Shared genetic study gives insights into the shared and distinct pathogenic immunity components of IgA nephropathy and SLE - Yue-miao Zhang; Xu-jie Zhou; Yan-Na Wang; Xing-zi Liu; Yong-Fei Wang; Yu-lung Lau; Wan-ling Yang; Hong Zhang (Molecular Genetics and Genomics, 2021)

Impact failure models and application condition of trees in debris-flow hazard mitigation - Ke Jin; Jian-gang Chen; Xiao-qing Chen; Wan-yu Zhao; Guang-wu Si; Xing-long Gong (Journal of Mountain Science, 2021)

Detection of Vestibular Schwannoma on Triple-parametric Magnetic Resonance Images Using Convolutional Neural Networks - Tzu-Hsuan Huang; Wei-Kai Lee; Chih-Chun Wu; Cheng-Chia Lee; Chia-Feng Lu; Huai-Che Yang; Chun-Yi Lin; Wen-Yuh Chung; Po-Shan Wang; Yen-Ling Chen; Hsiu-Mei Wu; Wan-You Guo; et al. (Journal of Medical and Biological Engineering, 2021)
Purpose The first step in typical treatment of vestibular schwannoma (VS) is to localize the tumor region, which is time-consuming and subjective because it relies on repeatedly reviewing different parametric magnetic resonance (MR) images. A reliable, automatic VS detection method can streamline the process. Methods A convolutional neural network architecture, namely YOLO-v2 with a residual network as a backbone, was used to detect VS tumors from MR images. To heighten performance, T1-weighted–contrast-enhanced, T2-weighted, and T1-weighted images were combined into triple-channel images for feature learning. The triple-channel images were cropped into three sizes to serve as input images of YOLO-v2. The VS detection effectiveness levels were evaluated for two backbone residual networks that downsampled the inputs by 16 and 32. Results The results demonstrated the VS detection capability of YOLO-v2 with a residual network as a backbone model. The average precision was 0.7953 for a model with 416 × 416-pixel input images and 16 instances of downsampling, when both the thresholds of confidence score and intersection-over-union were set to 0.5. In addition, under an appropriate threshold of confidence score, a high average precision, namely 0.8171, was attained by using a model with 448 × 448-pixel input images and 16 instances of downsampling. Conclusion We demonstrated successful VS tumor detection by using a YOLO-v2 with a residual network as a backbone model on resized triple-parametric MR images. The results indicated the influence of image size, downsampling strategy, and confidence score threshold on VS tumor detection.

An experimental determination of the relationship between the minimum height of landslide dams and the run-out distance of landslides - Kun-Ting Chen; Tien-Chien Chen; Xiao-Qing Chen; Hua-Yong Chen; Wan-Yu Zhao (Landslides, 2021)

Protective effects of Astragaloside IV against oxidative injury and apoptosis in cultured astrocytes by regulating Nrf2/JNK signaling - Jintao Yang; Chongyu Shao; Wentao Li; Haitong Wan; Yu He; Jiehong Yang (Experimental Brain Research, 2021)

Clinical characteristics of re-hospitalized COVID-19 patients with recurrent positive SARS-CoV-2 RNA: a retrospective study - Lei Pan; Runsheng Wang; Na Yu; Chao Hu; Junhong Yan; Xiaomin Zhang; Tao Wang; Jungui Hao; Fuquan Gao; Tonggang Liu; Jing Wang; Xiaojing Liu; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Correction to: Synthetic antimicrobial agents inhibit aflatoxin production - Jing Li; Qing-Qing Zhi; Jie Zhang; Xiao-Yu Yuan; Li-Hong Jia; Yu-Lin Wan; Qiu-Yun Liu; Jian-Rong Shi; Zhu-Mei He (Brazilian Journal of Microbiology, 2021)

Synthetic antimicrobial agents inhibit aflatoxin production - Jing Li; Qing-Qing Zhi; Jie Zhang; Xiao-Yu Yuan; Li-Hong Jia; Yu-Lin Wan; Qiu-Yun Liu; Jian-Rong Shi; Zhu-Mei He (Brazilian Journal of Microbiology, 2021)

Spatial distribution pattern in mammal and bird richness and their relationship with ecosystem services in Sanjiangyuan National Park, China - Hua-wei Wan; Hao-xin Li; Jin-hui Wu; Yu-ping Liu (Journal of Mountain Science, 2021)

Evaluation of the in-place adsorbed gas content of organic-rich shales using wireline logging data: a new method and its application - Xin Nie; Yu Wan; Da Gao; Chaomo Zhang; Zhansong Zhang (Frontiers of Earth Science, 2021)

Germination dynamics of allergenic fungal spores in respiratory mucus - Wan-Rou Lin; Szu-Yu Chen; Shih-Ching Hsiao; Pi-Han Wang (Aerobiologia, 2021)

KCNQ Channels in the Mesolimbic Reward Circuit Regulate Nociception in Chronic Pain in Mice - Hao-Ran Wang; Su-Wan Hu; Song Zhang; Yu Song; Xiao-Yi Wang; Lei Wang; Yang-Yang Li; Yu-Mei Yu; He Liu; Di Liu; Hai-Lei Ding; Jun-Li Cao (Neuroscience Bulletin, 2021)
Mesocorticolimbic dopaminergic (DA) neurons have been implicated in regulating nociception in chronic pain, yet the mechanisms are barely understood. Here, we found that chronic constructive injury (CCI) in mice increased the firing activity and decreased the KCNQ channel-mediated M-currents in ventral tegmental area (VTA) DA neurons projecting to the nucleus accumbens (NAc). Chemogenetic inhibition of the VTA-to-NAc DA neurons alleviated CCI-induced thermal nociception. Opposite changes in the firing activity and M-currents were recorded in VTA DA neurons projecting to the medial prefrontal cortex (mPFC) but did not affect nociception. In addition, intra-VTA injection of retigabine, a KCNQ opener, while reversing the changes of the VTA-to-NAc DA neurons, alleviated CCI-induced nociception, and this was abolished by injecting exogenous BDNF into the NAc. Taken together, these findings highlight a vital role of KCNQ channel-mediated modulation of mesolimbic DA activity in regulating thermal nociception in the chronic pain state.

First report of Alternaria alternata causing leaf spots of Liriodendron chinense × tulipifera in China - Guan-Qun Jin; Guang-Yao Mao; De-Wei Li; Yu Wan; Li-Hua Zhu (Journal of Plant Pathology, 2021)

MiR-150-5p regulate T cell activation in severe aplastic anemia by targeting Bach2 - Yingmei Li; Jifeng Yu; Fang Wang; Rong Guo; Haizhou Xing; Yali Chen; Dandan Chen; Xinsheng Xie; Dingming Wan; Zhongxing Jiang (Cell and Tissue Research, 2021)

Severe Zinc Deficiency Causes the Loss and Apoptosis of Olfactory Ensheathing Cells (OECs) and Olfactory Deficit - Yu Jiang; Lingqi Gu; Zilin Zhang; Jianya Zhao; Chunhua Wan (Journal of Molecular Neuroscience, 2021)

Microbiological profiles and antimicrobial resistance patterns of pediatric bloodstream pathogens in China, 2016–2018 - Yue Qiu; Junwen Yang; Yiping Chen; Jinhong Yang; Qingxiong Zhu; Chunhui Zhu; Shuangjie Li; Jing Liu; Chaomin Wan; Yu Zhu; Minxia Chen; Yi Xu; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Upper Ocean Temperatures Hit Record High in 2020 - Lijing Cheng; John Abraham; Kevin E. Trenberth; John Fasullo; Tim Boyer; Ricardo Locarnini; Bin Zhang; Fujiang Yu; Liying Wan; Xingrong Chen; Xiangzhou Song; Yulong Liu; et al. (Advances in Atmospheric Sciences, 2021)

Western North Pacific Tropical Cyclone Database Created by the China Meteorological Administration - Xiaoqin Lu; Hui Yu; Ming Ying; Bingke Zhao; Shuai Zhang; Limin Lin; Lina Bai; Rijin Wan (Advances in Atmospheric Sciences, 2021)
This paper describes the access to, and the content, characteristics, and potential applications of the tropical cyclone (TC) database that is maintained and actively developed by the China Meteorological Administration, with the aim of facilitating its use in scientific research and operational services. This database records data relating to all TCs that have passed through the western North Pacific (WNP) and South China Sea (SCS) since 1949. TC data collection has expanded over recent decades via continuous TC monitoring using remote sensing and specialized field detection techniques, allowing collation of a multi-source TC database for the WNP and SCS that covers a long period, with wide coverage and many observational elements. This database now comprises a wide variety of information related to TCs, such as historical or real-time locations (i.e., best track and landfall), intensity, dynamic and thermal structures, wind strengths, precipitation amounts, and frequency. This database will support ongoing research into the processes and patterns associated with TC climatic activity and TC forecasting.

Petrogenesis and tectonic setting of Late Devonian I-type granitic plutons in the Kekesala area, Chinese western Tianshan: implication for tectonic evolution of the North Tianshan Ocean - Zuopeng Wang; Yongjun Li; Gaoxue Yang; Le Wu; Yu Wan; Philemon Lindagato; Shuling Li (International Geology Review, 2021)

Evaluation of climate model simulations in representing the precipitation non‐stationarity by considering observational uncertainties - Yongjing Wan; Jie Chen; Ping Xie; Chong‐Yu Xu; Daiyuan Li (International Journal of Climatology, 2021)
The reliability of climate model simulations in representing the precipitation changes is one of the preconditions for climate‐change impact studies. However, the observational uncertainties hinder the robust evaluation of these climate model simulations. The goal of the present study is to evaluate the capacities of climate model simulations in representing the precipitation non‐stationarity in consideration of observational uncertainties. The mean of multiple observations from five observational precipitation datasets is used as a reference to quantify the uncertainty of observed precipitation and to evaluate the performance of climate model simulations. The non‐stationarity of precipitation was represented using the mean and variance of annual total precipitation and annual maximum daily precipitation for the 1982–2015 period. The results show that the spatial distributions of annual and extreme precipitation are similar for various observational datasets, while there has less agreement in the variance changes of extreme precipitation. Climate models are capable of representing the spatial distributions of the annual and extreme precipitation amounts at the global scales. In terms of the non‐stationarity, climate model simulations are capable of capturing the large‐scale spatial pattern of the trend in mean for annual precipitation. On the contrary, the simulations are less reliable in reproducing the change of extreme precipitation, as well as the trend of variance for annual precipitation. Overall, climate models are more reliable in simulating the mean of precipitation than the variance, and they are more reliable in simulating annual precipitation than extreme. Besides, the uncertainties of precipitation for both observations and simulations are much larger in monsoon regions than in other regions. This study suggests that considering observational uncertainties is necessary when using observational datasets as the reference to project future climate change and assess the impact of climate change on environments.

Decreased grain size1, a C3HC4-type RING protein, influences grain size in rice (Oryza sativa L.) - Xingjie Zhu; Shengzhong Zhang; Yaping Chen; Changlin Mou; Yunshuai Huang; Xi Liu; Jingli Ji; Jiangfeng Yu; Qixian Hao; Chunyan Yang; Mengying Cai; Thanhliem Nguyen; et al. (Plant Molecular Biology, 2021)

Restriction of groundwater recharge and evapotranspiration due to a fluctuating water table: a study in the Ordos Plateau, China - Ke-Yu Zhao; Xiao-Wei Jiang; Xu-Sheng Wang; Li Wan (Hydrogeology Journal, 2021)

Genetic diversity and population structure analysis of Emmenopterys henryi Oliv., an endangered relic species endemic to China - Yanli Niu; Arvind Bhatt; Yansong Peng; Wenxing Chen; Yuan Gao; Xuanhuai Zhan; Zhiyong Zhang; Wan Hu; Manzhen Song; Zhijun Yu (Genetic Resources and Crop Evolution, 2021)

Zinc Deficiency Aggravation of ROS and Inflammatory Injury Leading to Renal Fibrosis in Mice - Ran Xu; Miao-yu Chen; Wan Liang; Yu Chen; Meng-yao Guo (Biological Trace Element Research, 2021)

Dietary Selenium Deficiency Facilitated Reduced Stomatin and Phosphatidylserine Externalization, Increasing Erythrocyte Osmotic Fragility in Mice - Shi-yu Duan; Si-jie Chen; Wan Liang; Miao-yu Chen; Yu Chen; Meng-yao Guo (Biological Trace Element Research, 2021)

Molecular survey of selected viral pathogens in wild leopard cats (Prionailurus bengalensis) in Taiwan with an emphasis on the spatial and temporal dynamics of carnivore protoparvovirus 1 - Chen-Chih Chen; Ai-Mei Chang; Wan-Jhen Chen; Po-Jen Chang; Yu-Ching Lai; Hsu-Hsun Lee (Archives of Virology, 2021)

Effects of Different Component Contents of Colistin Methanesulfonate on the Pharmacokinetics of Prodrug and Formed Colistin in Human - Ya-Xin Fan; Yuan-Cheng Chen; Yi Li; Ji-Cheng Yu; Xing-Chen Bian; Xin Li; Wan-Zhen Li; Bei-Ning Guo; Hai-Lan Wu; Xiao-Fen Liu; Yu Wang; Xiao-Yong Xu; et al. (Pharmaceutical Research, 2021)

Climate‐induced nonlinearity in pelagic communities and non‐stationary relationships with physical drivers in the Kuroshio ecosystem - Shuyang Ma; Yongjun Tian; Caihong Fu; Haiqing Yu; Jianchao Li; Yang Liu; Jiahua Cheng; Rong Wan; Yoshiro Watanabe (Fish and Fisheries, 2021)
Climate‐induced nonlinearity in biological variability and non‐stationary relationships with physical drivers are crucial to understand responses of marine organisms to climate variability. These phenomena have raised concerns in the northeastern North Pacific, but are out of the spotlight in the northwestern North Pacific in spite of potential implications for this productive system under increased climate variability. Pelagic communities in the Kuroshio ecosystem have both ecological and economic importance. However, patterns of climate‐induced nonlinearity in pelagic communities are not well understood, and existence of non‐stationarity in their relationships with physical drivers remains obscure. Here, we compile large numbers of climatic, oceanic and biological long‐term time‐series data and employ diverse statistical techniques to reveal such climate‐induced nonlinearity and non‐stationarity. Results show that pelagic communities in the Tsushima and Pacific areas (major areas in the Kuroshio ecosystem) had regime shifts in the late 1990s and late 1980s, respectively. Winter sea surface temperatures in the Kuroshio Current path and in the eastern part of East China Sea, which are respectively affected by the Kuroshio Current and Siberian High, correlate with dominant variability patterns in their pelagic communities. Furthermore, non‐stationarity was identified with threshold years in the 1990s in the Tsushima area and in the 1980s in the Pacific area as a possible result of the declined variances in the Siberian High and Aleutian Low, respectively. Our findings provide insights on spatial differentiation of climate‐induced nonlinearity and non‐stationarity, which are valuable for the management of pelagic communities in the northwestern North Pacific under changing climatic conditions.

Heterosis-associated genes confer high yield in super hybrid rice - Tianzi Lin; Cong Zhou; Gaoming Chen; Jun Yu; Wei Wu; Yuwei Ge; Xiaolan Liu; Jin Li; Xingzhou Jiang; Weijie Tang; Yunlu Tian; Zhigang Zhao; et al. (Theoretical and Applied Genetics, 2020)
Key message Heterosis QTLs, including qSS7 and qHD8, with dominance effects were identified through GBS and large-scale phenotyping of CSSLs and hybrid F 1 populations in a paddy field. Abstract Heterosis has contributed immensely to agricultural production, but its genetic basis is unclear. We evaluated dominance effects by creating two hybrid populations: a B-homo set with a homozygous background and heterozygous chromosomal segments and a B-heter set with a heterozygous background and homozygous segments. This was achieved by crossing a set of 156 backcrossed-derived chromosome segment substitution lines (CSSLs) with their recurrent parent (9311), the male parent of the first super-high-yield hybrid Liangyoupei9 (LYP9), and with the female parent (PA64s) of the hybrid. The CSSLs were subjected to a genotyping-by-sequencing analysis to develop a genetic map of segments introduced from the PA64s. We evaluated the heterotic effects on eight yield-related traits in the hybrid variety and F 1 populations in large-scale field experiments over 2 years. Using a linkage map consisting of high-density SNPs, we identified heterosis-associated genes in LYP9. Five candidate genes contributed to the high yield of LYP9, with qSS7 and qHD8 repeatedly detected in both B-hybrid populations. The heterozygous segments harboring qSS7 and qHD8 showed dominance effects that contributed to the heterosis of yield components in the hybrid rice variety Liangyoupei9.

Microstructural properties and compressive strength of lime or/and cement solidified silt: a multi-scale study - Shaoyun Pu; Zhiduo Zhu; Liming Zhao; Weilong Song; Yu Wan; Wangwen Huo; Hairong Wang; Kai Yao; Lele Hu (Bulletin of Engineering Geology and the Environment, 2020)

LncRNA TUG1 promotes esophageal cancer development through regulating PLK1 expression by sponging miR-1294 - Mingzhu Zong; Wanting Feng; Li Wan; Xiaojuan Yu; Weiyong Yu (Biotechnology Letters, 2020)

Deformation mechanism and collapse treatment of the rock surrounding a shallow tunnel based on on-site monitoring - Hong-zhi Qiu; Xiao-qing Chen; Qi-hong Wu; Ren-chao Wang; Wan-yu Zhao; Ke-jiang Qian (Journal of Mountain Science, 2020)

Sphingosylphosphorylcholine alleviates hypoxia-caused apoptosis in cardiac myofibroblasts via CaM/p38/STAT3 pathway - Ying Li; Qi Qi; Wan-cheng Yang; Tian-liang Zhang; Chen-chen Lu; Yu-juan Yao; Wei-hua Kong; Jing Zhao (Apoptosis, 2020)

Interleukin-1β in hypothalamic paraventricular nucleus mediates excitatory renal reflex - Fen Zheng; Chao Ye; Guo-Wei Wan; Bing Zhou; Ying Tong; Jian-Zhen Lei; Qi Chen; Yue-Hua Li; Yu-Ming Kang; Guo-Qing Zhu (Pflügers Archiv - European Journal of Physiology, 2020)

Effects of high-intensity interval training on gut microbiota profiles in 12 months’ old ICR mice - Guiping Wang; Huanhuan Zhou; Lin Zhang; Ruyi Li; Li Luo; Zengli Yu; Zhongxiao Wan (Journal of Physiology and Biochemistry, 2020)

Unitary and binary remediations by plant and microorganism on refining oil-contaminated soil - Jia Jia Fei; Yun Yang Wan; Xin Yue He; Zhi Huan Zhang; Yu Xi Ying (Environmental Science and Pollution Research, 2020)

Mild-to-moderate iodine deficiency in a sample of pregnant women and salt iodine concentration from Zhejiang province, China - Zengli Yu; Canjie Zheng; Wangfeng Zheng; Zhongxiao Wan; Yongjun Bu; Guofu Zhang; Shibin Ding; Erhui Wang; Desheng Zhai; Zheng Feei Ma (Environmental Geochemistry and Health, 2020)

Structural Variability and Functional Prediction in the Epiphytic Bacteria Assemblies of Myriophyllum spicatum - Ling Xian; Tao Wan; Yu Cao; Junyao Sun; Ting Wu; Andrew Apudo Apudo; Wei Li; Fan Liu (Current Microbiology, 2020)

One new sterpurane sesquiterpene from cultures of the basidiomycete Pholiota nameko - Wan-Rong Niu; Cong-Liang Guo; Deng-Ji Lou; Rui-Ting Li; Qiao Xiang; Yu-Lin Zou; Xiu-Ming Cui; Xiao-Yan Yang (Natural Product Research, 2020)

Liquiritin inhibits proliferation and induces apoptosis in HepG2 hepatocellular carcinoma cells via the ROS-mediated MAPK/AKT/NF-κB signaling pathway - Jia-Ru Wang; Tian-Zhu Li; Cheng Wang; Shu-Mei Li; Ying-Hua Luo; Xian-Ji Piao; Yu-Chao Feng; Yi Zhang; Wan-Ting Xu; Yu Zhang; Tong Zhang; Shi-Nong Wang; et al. (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

Highly sensitive serological approaches for Pepino mosaic virus detection - Wan-qin He; Jia-yu Wu; Yi-yi Ren; Xue-ping Zhou; Song-bai Zhang; Ya-juan Qian; Fang-fang Li; Jian-xiang Wu (Journal of Zhejiang University-SCIENCE B, 2020)

Occurrence and partitioning of brominated flame retardants (BFRs) in indoor air and dust: a 15-month case study in a test home - Jia-Qi Guo; Yong-feng Li; Li-Yan Liu; Chun-Yan Huo; Yu Sun; Wan-li Ma; Zi-feng Zhang; Yi-Fan Li (Environmental Science and Pollution Research, 2020)

Clinical characteristic of 15 cases of cryptococcal meningitis treated with Ommaya reservoir - Yingfeng Wan; Xinwei Li; Yirong Wang; Yunsong Yu; Shuxu Yang (Acta Neurologica Belgica, 2020)

Genesis of the Linghu Au deposit in Xiaoqinling Region, Henan province, China: Constraints from fluid inclusions and isotope systematics - Wei Zeng; Zhi-gao Wang; Duo Wan; Feng-yue Sun; Cheng-dong Li; Reng-an Yu; Jia-ying Wang; Jian-chang Xu (Arabian Journal of Geosciences, 2020)

Comparative Variations of Extractive Nitrogenous Components and Quality in Fresh Muscle and Dried Product of Rabbitfish ( Siganus fuscescens ) in Taiwan - Yu-Ru Huang; Wan-Yi Huang; Hsiao-Chin Jen; Bi-Yu Liu; Ken-Meng Huang; Deng Fwu Hwang (Journal of Aquatic Food Product Technology, 2020)

Pharmacokinetics of seven major active components of Mahuang decoction in rat blood and brain by LC–MS/MS coupled to microdialysis sampling - Haoyu Wan; Lujia Pan; Yu Wang; Chang Li; Li Yu; Huifen Zhou; Haitong Wan; Yu He (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

miR-346-3p promotes osteoclastogenesis via inhibiting TRAF3 gene - Yingji Mao; Yu Chen; Yingxiao Fu; Jingjing Guan; Mengxiang Liang; Yansong Zhu; Fugen Yang; Feixiang Li; Zhe Zhang; Chuanfeng Wan; Pinghui Zhou (In Vitro Cellular & Developmental Biology - Animal, 2020)

Alternative Evaluation to Earthworm Toxicity Test in Polychlorinated Biphenyls Spiked and Remediated Soils - Chungui Yu; Congkai Zhang; Zhe Ye; Xianjin Tang; Jixing Wan; Chaofeng Shen (Bulletin of Environmental Contamination and Toxicology, 2020)

Treatment of High Concentration Acid Plasticizer Wastewater by Ozone Microbubble Oxidation - Xiaohui Wan; Li Zhang; Zhiguo Sun; Wei Yu; Hongyong Xie (Water, Air, & Soil Pollution, 2020)

Association of Polygenic Risk Score with Age at Onset and Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease in a Chinese Cohort - Wei-Wei Li; Zhen Wang; Dong-Yu Fan; Ying-Ying Shen; Dong-Wan Chen; Hui-Yun Li; Ling Li; Heng Yang; Yu-Hui Liu; Xian-Le Bu; Wang-Sheng Jin; Fan Zeng; et al. (Neuroscience Bulletin, 2020)

Performance Enhancement Model for Rainfall Forecasting Utilizing Integrated Wavelet-Convolutional Neural Network - Kai Lun Chong; Sai Hin Lai; Yu Yao; Ali Najah Ahmed; Wan Zurina Wan Jaafar; Ahmed El-Shafie (Water Resources Management, 2020)

Small Molecules that Promote Self-Renewal of Stem Cells and Somatic Cell Reprogramming - Guofang Chen; Yu’e Guo; Chao Li; Shuangdi Li; Xiaoping Wan (Stem Cell Reviews and Reports, 2020)

Ultrastructural Characteristics of DHA-Induced Pyroptosis - Deron R. Herr; Ting Yu Amelia Yam; Wan Shun Daniel Tan; Sally Shuxian Koh; Wai Shiu Fred Wong; Wei-Yi Ong; Kanokporn Chayaburakul (NeuroMolecular Medicine, 2020)
Microglial cells are resident macrophages of the central nervous system (CNS) that respond to bioactive lipids such as docosahexaenoic acid (DHA). Low micromolar concentrations of DHA typically promote anti-inflammatory functions of microglia, but higher concentrations result in a form of pro-inflammatory programmed cell death known as pyroptosis. This study used scanning electron microscopy (SEM) and transmission electron microscopy (TEM) to investigate the morphological characteristics of pyroptosis in BV-2 microglial cells following exposure to 200 µM DHA. Vehicle-treated cells are characterized by extended processes, spine-like projections or 0.4 to 5.2 µm in length, and numerous extracellular vesicles (EVs) tethered to the surface of the plasma membrane. In contrast to vehicle-treated cells, gross abnormalities are observed after treating cells with 200 µM DHA for 4 h. These include the appearance of numerous pits or pores of varying sizes across the cell surface, structural collapse and flattening of the cell shape. Moreover, EVs and spines were lost following DHA treatment, possibly due to release from the cell surface. The membrane pores appear after DHA treatment initially measured ~ 30 nm, consistent with the previously reported gasdermin D (GSDMD) pore complexes. Complete collapse of cytoplasmic organization and loss of nuclear envelope integrity were also observed in DHA-treated cells. These processes are morphologically distinct from the changes that occur during cisplatin-induced apoptosis, such as the appearance of apoptotic bodies and tightly packed organelles, and the maintenance of EVs and nuclear envelope integrity. Cumulatively, this study provides a systematic description of the ultrastructural characteristics of DHA-induced pyroptosis, including distinguishing features that differentiate this process from apoptosis.

Genome-Wide Analysis of LAZ1 Gene Family from Maize - Bing Liang Liu; Hao Qiang Yu; Qian Wen; Feng Ling Fu; Wan Chen Li (Journal of Plant Growth Regulation, 2020)

Lipid content and fatty acid composition of freshwater eels Anguilla japonica caught in different seasons and locations in South Korea - Kiuk Lee; Yu Jeong Kim; Yang Ki Hong; Mi Young Song; Wan Ok Lee; Keum Taek Hwang (Fisheries Science, 2020)

Multiple genetic factors affecting the pharmacokinetic and pharmacodynamic processes of tacrolimus in Chinese myasthenia gravis patients - Huan-Yu Meng; Xi Li; Wan-Lin Jin; Cheng-Kai Yan; Xiao-Hua Dong; Qiu Xu; Yu-Yao Peng; Zhi-Bin Li; Yi Li; Zhao-Hui Luo; Li-Qun Xu; Huan Yang (European Journal of Clinical Pharmacology, 2020)

Effects of Elevated Ozone Concentrations on Root Characteristics and Soil Properties of Elaeocarpus sylvestris and Michelia chapensis - Lan Pan; Wan-qi Lin; Ming Yu; Gan-wen Lie; Li Xue; Hong-yue Chen (Bulletin of Environmental Contamination and Toxicology, 2020)

Gene regulations and delivery vectors for treatment of cancer - Ming Chen; Yu-Xin Ren; Ying Xie; Wan-Liang Lu (Journal of Pharmaceutical Investigation, 2020)

The effects of mesoscale oceanographic structures and ambient conditions on the catch of albacore tuna in the South Pacific longline fishery - Cheng Zhou; Pingguo He; Liuxiong Xu; Pascal Bach; Xuefang Wang; Rong Wan; Hao Tang; Yu Zhang (Fisheries Oceanography, 2020)
Albacore tuna ( Thunnus alalunga ) exhibit patchy concentrations associated with biological process at a wide range of spatial scales, resulting in variations in their catchability by fishing gears. Here, we investigated the association of catch variation for pelagic longlines in the South Pacific Ocean with oceanographic mesoscale structures (in horizontal dimension) and ambient conditions (in vertical dimension). The distribution of albacore tuna as indicated by catch per unit effort (CPUE) of longlines was significantly related to the presence of mesoscale structures, with higher CPUE found at locations closer to thermal fronts and with greater gradient magnitudes, as well as areas marked by peripheral contour line of the anticyclone indicated by Sea Surface Height Anomalies ~0.05 m. Surface mesoscale current velocity had the negative effect on the catch, probably as a result of decreased catchability by shoaling the hook depth. Vertical distribution of albacore in the survey region of South Pacific Ocean was hardly restricted by ambient temperature and oxygen concentration, though effect of ambient temperature was relevant and showed a negatively linear correlation with CPUE at the range of 20–24°C. On the contrary, albacore distribution was evidently dominated by the water depth and showed strong preference on water depth of 200 m, which was likely a representative feeding layer. The presence of prey resources and their accessibility by albacore revealed by mesoscale structures in the biological and physical processes, and catchability determined by the location of the baited hooks comprehensively contribute to the variability of catch.

Red cell distribution width/albumin ratio is associated with 60-day mortality in patients with acute respiratory distress syndrome - Jung-Wan Yoo; Sunmi Ju; Seung Jun Lee; Yu Ji Cho; Jong Deog Lee; Ho Cheol Kim (Infectious Diseases, 2020)

Correction to: Limb Remote Ischemic Preconditioning Reduces Repeated Ketamine Exposure-Induced Adverse Effects in the Developing Brain of Rats - Ying Liu; An Qi Li; Wan Ma; Yu Bo Gao; Li Qin Deng; Chun Zhang; Jin Hai Meng (Journal of Molecular Neuroscience, 2020)

Tirofiban for acute ischemic stroke: systematic review and meta-analysis - Jinhong Gong; Jingjing Shang; Hai Yu; Qian Wan; Dan Su; Zhiqiang Sun; Guangjun Liu (European Journal of Clinical Pharmacology, 2020)

The effect of pH on the sorption of gold nanoparticles on illite - Yuhong Fu; Quan Wan; Zonghua Qin; Xin Nie; Wenbin Yu; Shanshan Li (Acta Geochimica, 2020)

Unconformity-controlled dissolution contributes to reservoirs in the carbonate-rich Permian Fengcheng Formation, northwestern Junggar Basin, China - Kuanhong Yu; Yingchang Cao; Longwei Qiu; Peipei Sun; Yongqiang Yang; Changsheng Qu; Dewen Lei; Xiyu Jia; Min Wan; Zhijie Zhang (Carbonates and Evaporites, 2020)

Validation and correction of sea surface salinity retrieval from SMAP - Sisi Qin; Hui Wang; Jiang Zhu; Liying Wan; Yu Zhang; Haoyun Wang (Acta Oceanologica Sinica, 2020)

Exercise training reduces the risk of opportunistic infections after acute exercise and improves cytokine antigen recognition - Kyung-Wan Baek; Jin-Ok Jo; Yun-Jeong Kang; Kyoung Seob Song; Hak Sun Yu; Jung-Jun Park; Yung Hyun Choi; Hee-Jae Cha; Mee Sun Ock (Pflügers Archiv - European Journal of Physiology, 2020)

L-type Calcium Channels are Involved in Iron-induced Neurotoxicity in Primary Cultured Ventral Mesencephalon Neurons of Rats - Yu-Yu Xu; Wen-Ping Wan; Sha Zhao; Ze-Gang Ma (Neuroscience Bulletin, 2020)

Differences in macrophage polarization in the adipose tissue of obese mice under various levels of exercise intensity - Kyung-Wan Baek; Da-In Lee; Shin Ae Kang; Hak Sun Yu (Journal of Physiology and Biochemistry, 2020)

Record-Setting Ocean Warmth Continued in 2019 - Lijing Cheng; John Abraham; Jiang Zhu; Kevin E. Trenberth; John Fasullo; Tim Boyer; Ricardo Locarnini; Bin Zhang; Fujiang Yu; Liying Wan; Xingrong Chen; Xiangzhou Song; et al. (Advances in Atmospheric Sciences, 2020)

Agrobacterium-mediated genetic transformation of Chinese chestnut (Castanea mollissima Blume) - Zhi-lin Sun; Xiao Li; Wan Zhou; Jun-di Yan; Yue-rong Gao; Xiao-wei Li; Jia-chen Sun; Ke-feng Fang; Qing Zhang; Yu Xing; Ling Qin; Qing-qin Cao (Plant Cell, Tissue and Organ Culture (PCTOC), 2020)
Chinese chestnut ( Castanea mollissima ) is an important germplasm resource for the breeding of Castanea species worldwide with vital ecological and economic value. Biotechnology overcomes the limitations of traditional breeding and accelerates germplasm improvement. However, a genetic transformation system for Chinese chestnut has not yet been established. In this study, a stable and efficient Agrobacterium -mediated genetic transformation method for Chinese chestnut is described. Embryogenic calli of C. mollissima cv. ‘Yanshanhongli’ were used as the target material. The sensitivity of embryogenic calli to kanamycin was determined, whereby the proliferation of non-transformed calli was completely inhibited at 180 mg/L. Antibiotic inhibition results for Chinese chestnut embryogenic calli showed that 50 mg/L cefotaxime and 500 μM timentin completely inhibited the growth of Agrobacterium tumefaciens but did not affect the normal growth of Chinese chestnut embryogenic calli. When embryogenic calli were co-cultured for 2 days with Agrobacterium tumefaciens strain AGL1 harboring the PBI121-EGFP plasmid, an embryogenic callus transformation efficiency of 4.55% was obtained, and two transgenic chimera were acquired. This Agrobacterium -mediated transformation system for Chinese chestnut provides a fundamental platform for genetic improvement of core germplasm and for further verification of gene function.

Modified stepwise mini-incision microdissection testicular sperm extraction: a useful technique for patients with a history of orchidopexy affected by non-obstructive azoospermia - Peng Li; Chen-cheng Yao; Er-lei Zhi; Yuan Xu; Zhong Wan; Ying-chuan Jiang; Yu-hua Huang; Yue-hua Gong; Hui-xing Chen; Ru-hui Tian; Chao Yang; Liang-yu Zhao; et al. (Journal of Zhejiang University-SCIENCE B, 2020)

The High Diversity and Variable Susceptibility of Clinically Relevant Acremonium-Like Species in China - Limin Yao; Hong Wang; Zhe Wan; Ruoyu Li; Jin Yu (Mycopathologia, 2019)

Interception of sulfate deposition from a closed canopy to a forest gap edge canopy in a subalpine dragon spruce plantation - Yu Zhang; Fu-zhong Wu; Bo Tan; Zhen-feng Xu; Han Li; Jun-cheng Liu; Hai-rong Zhao; Si-yi Tan; Cheng-ming You; Wan-qin Yang (Journal of Mountain Science, 2019)

Climatology and change of extreme precipitation events in Taiwan based on weather types - Yi‐chao Wu; S.‐Y. Simon Wang; Yi‐Chiang Yu; Chu‐Ying Kung; An‐Hsiang Wang; Sebastian A. Los; Wan‐Ru Huang (International Journal of Climatology, 2019)
Taiwan's most significant natural hazards are caused by hydrological extremes resulting from excessive precipitation. The threat of extreme precipitation is posed by several different types of weather patterns that affect Taiwan. This study examined the bi‐decadal changes in rainfall by defining an extreme precipitation occurrence (EPO) for a range of event durations from 1 to 24 hr. Three major weather types affecting EPO in Taiwan were identified from 1993 to 2015: the front type consisting of either a frontal zone or convective systems developing with an apparent Meiyu cloudband, diurnal rainfall events when no apparent synoptic features are present, and a tropical cyclone (TC) type according to the maximum sustained wind radius of a TC. Results show that TC‐type events have the greatest overall contribution to EPO at longer (>6 hr) durations. Diurnal/afternoon convection events contribute most to the shorter ( 6 hr) EPO associated with the TC‐type events in summer. The distinction between EPO trends for the entire island of Taiwan and for the Taipei metropolitan area alone (northern Taiwan, population of 7 million) were compared, and an intriguing interannual variation is reported in the TC‐type EPO associated with the TC season 1 year to a year and half just before an El Niño–Southern Oscillation event. The analysis here provides refined statistical distributions of extreme rainfall, and these can contribute to the revision of governmental definitions for weather disasters that are used in mitigation and response strategies.

Evaluating and Predicting the Effects of Land Use Changes on Water Quality Using SWAT and CA–Markov Models - Xiaoyan Gong; Jianmin Bian; Yu Wang; Zhuo Jia; Hanli Wan (Water Resources Management, 2019)

Genetic Association Between NGFR, ADAM17 Gene Polymorphism, and Parkinson’s Disease in the Chinese Han Population - Wei-Wei Li; Ying-Ying Shen; Dong-Wan Chen; Hui-Yun Li; Qian-Qian Shi; Jing Mei; Heng Yang; Fa-Ying Zhou; An-Yu Shi; Tao Zhang; Xiu-Qing Yao; Zhi-Qiang Xu; et al. (Neurotoxicity Research, 2019)

QTL mapping and genetic effect of chromosome segment substitution lines with excellent fiber quality from Gossypium hirsutum × Gossypium barbadense - Shao-qi Li; Ai-ying Liu; Ling-lei Kong; Ju-wu Gong; Jun-wen Li; Wan-kui Gong; Quan-wei Lu; Peng-tao Li; Qun Ge; Hai-hong Shang; Xiang-hui Xiao; Rui-xian Liu; et al. (Molecular Genetics and Genomics, 2019)

The variation of rice cultivars in Cd toxicity and distribution of the seedlings and their root histochemical examination - Wan-Ting Chiao; Chun-Hui Yu; Kai-Wei Juang (Paddy and Water Environment, 2019)

Transformation of eIF5B1 gene into Chrysanthemum to gain calluses of high temperature tolerance - Zhi-Qin Wei; Meng-Jiao Lv; Wen Wan; Fei Yu; Xiao-Ying Cao; Lai-Sheng Meng (Biologia, 2019)

Profiling the microbial contamination in aviation fuel from an airport - Dong Hu; Wenfang Lin; Jie Zeng; Peng Wu; Menglu Zhang; Lizheng Guo; Chengsong Ye; Kun Wan; Xin Yu (Biofouling, 2019)

Synergies in Operational Oceanography: The Intrinsic Need for Sustained Ocean Observations - Fraser Davidson; Aida Alvera-Azcárate; Alexander Barth; Gary B. Brassington; Eric P. Chassignet; Emanuela Clementi; Pierre De Mey-Frémaux; Prasanth Divakaran; Christopher Harris; Fabrice Hernandez; Patrick Hogan; Lars R. Hole; et al. (Frontiers in Marine Science, 2019)

Effects of different potassium fertilizers on cadmium uptake by three crops - Kang Wang; Guiping Fu; Yao Yu; Yanan Wan; Zhe Liu; Qi Wang; Jingsuo Zhang; Huafen Li (Environmental Science and Pollution Research, 2019)

Characterization of the complete mitochondrial genome and phylogenetic analysis of Pelodiscus sinensis, a mutant Chinese soft-shell turtle - Jun Zhang; Qingyan Zhou; Xiaoli Yang; Peng Yu; Weishang Zhou; Yuan Gui; Xia Ouyang; Quan Wan (Conservation Genetics Resources, 2019)

New insights into mechanism of bisphenol analogue neurotoxicity: implications of inhibition of O-GlcNAcase activity in PC12 cells - Yu-Xin Gu; Xiao-Xing Liang; Nuo-Ya Yin; Yu Yang; Bin Wan; Liang-Hong Guo; Francesco Faiola (Archives of Toxicology, 2019)

Transcriptome analysis reveals downregulation of virulence-associated genes expression in a low virulence Verticillium dahliae strain - Lirong Jin; Dong Chen; Shengjie Liao; Yu Zhang; Fengyun Yu; Peng Wan; Dazhao Yu; Qijia Wu; Yi Zhang (Archives of Microbiology, 2019)

Interpreting air temperature generated from urban climatic map by urban morphology in Taipei - Yu-Cheng Chen; Tzu-Wen Lo; Wan-Yu Shih; Tzu-Ping Lin (Theoretical and Applied Climatology, 2019)

WSL6 encoding an Era-type GTP-binding protein is essential for chloroplast development in rice - Yinglun Sun; Yunlu Tian; Shuhan Cheng; Yunlong Wang; Yuanyuan Hao; Jianping Zhu; Xiaopin Zhu; Yuanyan Zhang; Mingzhou Yu; Jie Lei; Xiuhao Bao; Hongming Wu; et al. (Plant Molecular Biology, 2019)

Thymosin Alpha-1 Inhibits Complete Freund’s Adjuvant-Induced Pain and Production of Microglia-Mediated Pro-inflammatory Cytokines in Spinal Cord - Yunlong Xu; Yanjun Jiang; Lin Wang; Jiahua Huang; Junmao Wen; Hang Lv; Xiaoli Wu; Chaofan Wan; Chuanxin Yu; Wenjie Zhang; Jiaying Zhao; Yinqi Zhou; et al. (Neuroscience Bulletin, 2019)

Yangyin Tongnao granules enhance neurogenesis in the peri-infarct area and upregulate brain-derived neurotrophic factor and vascular endothelial growth factor after focal cerebral ischemic infarction in rats - Yu Wang; Jiehong Yang; Haixia Du; Hongbo Zhang; Haitong Wan; Yu He (Molecular Biology Reports, 2019)

Ginsenoside Rg1 Prevents Chemotherapy-Induced Cognitive Impairment: Associations with Microglia-Mediated Cytokines, Neuroinflammation, and Neuroplasticity - Dong-Dong Shi; Yu-Hua Huang; Cora Sau Wan Lai; Celia M. Dong; Leon C. Ho; Xiao-Yang Li; Ed X. Wu; Qi Li; Xiao-Min Wang; Yong-Jun Chen; Sookja Kim Chung; Zhang-Jin Zhang (Molecular Neurobiology, 2019)

Prevalence of mycotoxins in feed and feed ingredients between 2015 and 2017 in Taiwan - Ching-Kuo Yang; Yeong-Hsiang Cheng; Wan-Ting Tsai; Rou-Wan Liao; Chia-Sheng Chang; Wan-Chu Chien; Jia-Cin Jhang; Yu-Hsiang Yu (Environmental Science and Pollution Research, 2019)

Adsorption characteristics of copper ion on nanoporous silica - Yanhui Niu; Wenbin Yu; Zonghua Qin; Xin Nie; Shuguang Yang; Quan Wan (Acta Geochimica, 2019)

Effects of occurrence record number, environmental variable number, and spatial scales on MaxEnt distribution modelling for invasive plants - Ji-Zhong Wan; Chun-Jing Wang; Fei-Hai Yu (Biologia, 2019)

Antifungal Susceptibility Profile of Candida Albicans Isolated from Vulvovaginal Candidiasis in Xinjiang Province of China - Liang Yan; Xiao-dong Wang; Seyedmojtaba Seyedmousavi; Juan-na Yuan; Palida Abulize; Wei-hua Pan; Nong Yu; Ya-li Yang; Hai-qing Hu; Wan-qing Liao; Shu-wen Deng (Mycopathologia, 2019)

Effect of selenium on the subcellular distribution of cadmium and oxidative stress induced by cadmium in rice (Oryza sativa L.) - Yanan Wan; Kang Wang; Zhe Liu; Yao Yu; Qi Wang; Huafen Li (Environmental Science and Pollution Research, 2019)

MiR-15b-5p is Involved in Doxorubicin-Induced Cardiotoxicity via Inhibiting Bmpr1a Signal in H9c2 Cardiomyocyte - Guo-xing Wan; Lan Cheng; Hai-lun Qin; Yun-zhang Zhang; Ling-yu Wang; Yong-gang Zhang (Cardiovascular Toxicology, 2019)

Transcriptomic responses of the marine cyanobacterium Prochlorococcus to viral lysis products - Xiaoting Fang; Yaxin Liu; Yao Zhao; Yue Chen; Riyue Liu; Qi‐Long Qin; Gang Li; Yu‐Zhong Zhang; Wan Chan; Wolfgang R. Hess; Qinglu Zeng (Environmental Microbiology, 2019)
Summary Viral infection of marine phytoplankton releases a variety of dissolved organic matter (DOM). The impact of viral DOM (vDOM) on the uninfected co‐occurring phytoplankton remains largely unknown. Here, we conducted transcriptomic analyses to study the effects of vDOM on the cyanobacterium Prochlorococcus , which is the most abundant photosynthetic organism on Earth. Using Prochlorococcus MIT9313, we showed that its growth was not affected by vDOM, but many tRNAs increased in abundance. We tested tRNA‐gly and found that its abundance increased upon addition of glycine. The decreased transcript abundances of N metabolism genes also suggested that Prochlorococcus responded to organic N compounds in vDOM. Addition of vDOM to Prochlorococcus reduced the maximum photochemical efficiency of photosystem II and CO 2 fixation while increasing its respiration rate, consistent with differentially abundant transcripts related to photosynthesis and respiration. One of the highest positive fold‐changes was observed for the 6S RNA, a noncoding RNA functioning as a global transcriptional regulator in bacteria. The high level of 6S RNA might be responsible for some of the observed transcriptional responses. Taken together, our results revealed the transcriptional regulation of Prochlorococcus in response to viral lysis products and suggested its metabolic potential to utilize organic N compounds.

Limb Remote Ischemic Preconditioning Reduces Repeated Ketamine Exposure-Induced Adverse Effects in the Developing Brain of Rats - Ying Liu; An Qi Li; Wan Ma; Yu Bo Gao; Li Qin Deng; Chun Zhang; Jin Hai Meng (Journal of Molecular Neuroscience, 2019)

Lidar Observations of the Typhoon Boundary Layer Within the Outer Rainbands - Yuan-Shiang Tsai; Jiun-Jih Miau; Chao-Ming Yu; Wan-Ting Chang (Boundary-Layer Meteorology, 2019)

The anxiolytic effects of Bai Le Mian capsule, a traditional Chinese hypnotic in mice - Tian-Xiao Wang; Yu-Er Wu; Wei Xu; Wan-Kun Gong; Jian Ni; Wei-Min Qu; Zhi-Li Huang (Sleep and Biological Rhythms, 2019)

Comparative mitogenomic and phylogenetic analysis of Apalone spinifera and Apalone ferox (Testudines: Trionychidae) - Peng Yu; Xiaoli Yang; Weishang Zhou; Wentao Yang; Li Zhou; Xuan Liu; Quan Wan; Jun Zhang (Genetica, 2019)

Chemotherapy-Induced Cognitive Impairment Is Associated with Cytokine Dysregulation and Disruptions in Neuroplasticity - Dong-Dong Shi; Yu-Hua Huang; Cora Sau Wan Lai; Celia M. Dong; Leon C. Ho; Ed X. Wu; Qi Li; Xiao-Min Wang; Sookja Kim Chung; Pak Chung Sham; Zhang-Jin Zhang (Molecular Neurobiology, 2019)

Observed characteristics of tidal currents and mean flow in the northern Yellow Sea - Congcong Bi; Xianwen Bao; Yang Ding; Cong Zhang; Yu Wang; Biao Shen; Kai Wan (Journal of Oceanology and Limnology, 2019)

Relative soil moisture in China’s farmland - Guofeng Zhu; Hanxiong Pan; Yu Zhang; Huiwen Guo; Leilei Yong; Qiaozhuo Wan; Huiying Ma; Sen Li (Journal of Geographical Sciences, 2019)

Isolation and characterization of duck adenovirus 3 circulating in China - Shaohua Shi; Rongchang Liu; Chunhe Wan; Longfei Cheng; Zhen Chen; Guanghua Fu; Hongmei Chen; Qiuling Fu; Yu Huang (Archives of Virology, 2019)

2018 Continues Record Global Ocean Warming - Lijing Cheng; Jiang Zhu; John Abraham; Kevin E. Trenberth; John T. Fasullo; Bin Zhang; Fujiang Yu; Liying Wan; Xingrong Chen; Xiangzhou Song (Advances in Atmospheric Sciences, 2019)

Alginate-based composites for environmental applications: a critical review - Bing Wang; Yongshan Wan; Yuling Zheng; Xinqing Lee; Taoze Liu; Zebin Yu; Jun Huang; Yong Sik Ok; Jianjun Chen; Bin Gao (Critical Reviews in Environmental Science and Technology, 2019)

Neonatal Maternal Deprivation Followed by Adult Stress Enhances Adrenergic Signaling to Advance Visceral Hypersensitivity - Wan-Jie Du; Shufen Hu; Xin Li; Ping-An Zhang; Xinghong Jiang; Shan-Ping Yu; Guang-Yin Xu (Neuroscience Bulletin, 2019)

Identification of the copy number variant biomarkers for breast cancer subtypes - Xiaoyong Pan; XiaoHua Hu; Yu-Hang Zhang; Lei Chen; LiuCun Zhu; ShiBao Wan; Tao Huang; Yu-Dong Cai (Molecular Genetics and Genomics, 2019)

The analgesic effect and possible mechanisms by which koumine alters type II collagen-induced arthritis in rats - Gui-Lin Jin; Jian Yang; Wan-Qing Chen; Jie Wang; Hong-Qiang Qiu; Ying Xu; Chang-Xi Yu (Journal of Natural Medicines, 2019)

Factors controlling spatiotemporal variations in stable nitrogen isotopes of Trachurus japonicus larvae and juveniles in the East China Sea - Weiping Mei; Yu Umezawa; Xin Wan; Chiyuki Sassa; Motomitsu Takahashi (Fisheries Science, 2019)

COX6B1 relieves hypoxia/reoxygenation injury of neonatal rat cardiomyocytes by regulating mitochondrial function - Wei Zhang; Yu Wang; Junzhe Wan; Pengbo Zhang; Fei Pei (Biotechnology Letters, 2019)

Experimental characterization and dependence of rock fracture permeability on 3D stresses - Yu Zhao; Chaolin Wang; Yanlin Zhao; Li He; Wen Wan; Yongfa Zhang (Arabian Journal of Geosciences, 2019)