Distribution characteristics and relationships of soil organic carbon and inorganic carbon in a typical wetland in semi-arid area of Northeast China - Yuan Xin; Xianglong Xing; Long Chen; Zhongsheng Zhang; Walian Du; Shouzheng Tong; Mingye Zhang; Yu An; Geng Cui; Dongmei Zheng; Guangtao Liu (CATENA, 2025)

Mg isotopes and in-situ Rb Sr dating reveal carbonate-rich and carbonate-poor sediments in mantle sources of lamproites beneath the North China Craton - Kaizhang Yu; Yongsheng Liu; Wei Chen; Chunfei Chen; Chutian Shu; Stephen F. Foley; Jixing Li; Zhaochu Hu (Chemical Geology, 2025)

Carbonate-associated phosphorus as a proxy for porewater alkalinity and phosphate level during marine carbonate authigenesis in deep-subsurface sediments - Yu Hu; Yu Gao; Jörn Peckmann; Linying Chen; Duofu Chen; Dong Feng (Chemical Geology, 2025)

A binary-medium-based multiscale constitutive model for stabilized expansive soil considering the influence of freeze-thaw cycles - Cong Chen; Yunyong He; Bo Xiang; Enlong Liu; Yanyang Yu (Cold Regions Science and Technology, 2025)

Dialysis-assisted control significantly enables stable long-term unaerated partial nitrification in a microalgal-bacterial consortium treating hydrolyzed urine - Zimu Li; Zhipeng Chen; Yue Xie; Yanbing Hu; Shiling Xu; Sheng Yu; Shuang Qiu; Shijian Ge (Bioresource Technology, 2025)

Protein language model-assisted directed evolution of cyclodextrinase Enables Precision α-O-Oligosaccharide synthesis - Ting Nie; Zhenxin Yan; Hao Liu; Xiudian Zhang; Weiwei Zhong; Qin Chen; Changbin Zhu; Liang Hong; Guang-yu Yang (Bioresource Technology, 2025)

Optimizing microalgal-bacterial granular sludge performance with solar-LED nighttime light supplementation for improved wastewater treatment - Can Tong; Lingyang Zhang; Changqing Chen; Bin Ji; Anjie Li; Xiaoyuan Zhang; Yu Liu (Bioresource Technology, 2025)

Indole-3-acetic acid-mediated root exudates as potential inhibitors of antibiotic resistance genes in the rhizosphere microbiome: Mechanistic insights into microbial community assembly and resistome dissemination - Ping Chen; Kaifeng Yu; Kaimin Yang; Dong Zhang; Peng Li; Yiliang He (Bioresource Technology, 2025)

Machine learning coupling microbial succession to decipher gas stripping-reinforced sulfate reduction for hydrogen sulfide removal - Ting-Ting Zhang; Ei Myat Mon Oo; Bi-Long Chen; Lin Liu; Quan-Bao Zhao; Jia-Cheng E. Yang; Yu-Ming Zheng (Bioresource Technology, 2025)

High-quality, low-nitrogen bio-oil from kitchen waste via K2CO3-catalyzed solvothermal liquefaction in recycled ethanol–water co-solvent - Mi Yan; Linyi Chen; Yu Liu; Hongyu Sun; Haihua Zhang; Rendong Zheng; Yuxuan Ying (Bioresource Technology, 2025)

Computational-assisted protein engineering to develop thermostable and highly active catalase for industrial and biocatalytic applications - Shuai Xu; Ya-min Chen; Xiang-yu Meng; Ru Pan; Ao-xuan Yan; Zhi-min Li; Zong-lin Li (Bioresource Technology, 2025)

BIM-integrated LCA framework for prefabricated buildings with automated benchmarking and visual decision support - Xuan Ma; Mengqi Huang; Xilin Chen; Yu Bai; Qian-Bing Zhang (Building and Environment, 2025)

Biphasic system and benign polymerization enable full utilization of biomass components - Jiakang Liang; Jingyi Han; Man Zhou; Xiaojie Yu; Li Chen; Cunshan Zhou (Biomass and Bioenergy, 2025)

Extraction of polysaccharides from waste medium as functional ingredients - Nan Zhao; Zhongyang Liu; Xinyue Fan; Muhammad Naveed Sheas; Xinyi Chen; Ting Yu; Fujie Yan (Bioresource Technology Reports, 2025)

Revealing GHG-NH3 emission mechanisms: A comparison of food waste composting and biogas residue composting - Bao Yu; Mingyue Xu; Yue Chen; Yuecen Dong; Xingkun Xu; Luoqi Wang; Guodi Zheng; Jianguo Liu (Bioresource Technology Reports, 2025)

Sesquiterpenoids and monoterpenoids from the aerial parts of Sarcandra glabra (Thunb.) Nakai - Yang Liu; Jie Chen; Wan-Wan Yu; Yong-Ming Luo; Meng-Li He; Xin-Yu Chen; Fang-You Chen (Biochemical Systematics and Ecology, 2025)

A new norlignan and other compounds from Artemisia frigida Willd - Xin-Ya Dong; Ru-Ya Li; Hong-Xia Tang; Ya-Jie Li; Jun Chen; Jin-Guo Luo; Na Yu; Xiang-Wei Xu; Xu-Dong Zhou (Biochemical Systematics and Ecology, 2025)

Phenolics from Toxicodendron vernicifluum (Stokes) F. A. Barkley (Anacardiaceae) and their chemotaxonomic significance - Cai-Wen Meng; Wen-Jing Zu; Jie Liu; Xue Qiu; Hong-Yun Bai; Jian-Yu Liu; Yong-Nan Xu; Mei-Chen Li (Biochemical Systematics and Ecology, 2025)

Cytotoxic stilbenoid from the leaves and stems of Cassia nodosa - Qionghui Sun; Limei Yu; Changyan Shao; Chen Qing; Haji Akber Aisa; Rui Zhan; Yegao Chen (Biochemical Systematics and Ecology, 2025)

Emission estimates of ozone-depleting hydrochlorofluorocarbons for China inferred from new observations and inverse modeling - Ye Chen; Xiaoyi Hu; Kuang Xiao; Xiao Zhang; Mingzhu Li; Tong Ye; Bowei Li; Mingrui Ji; Bo Yao; Haibo Yu; Xuekun Fang; Li Tan; et al. (Atmospheric Environment, 2025)

Anthropogenic aerosol feedbacks intensify air pollution and weather variability over China - Jixiang Li; Haipeng Yu; Andrea Pozzer; Kai Tang; Chenhui Jia; Zeyong Hu; Siyu Chen; Yunsai Zhu; Yuling Hu; Bofei Zhang; Hongyu Luo; Zekui Jiang; et al. (Atmospheric Environment, 2025)

Reactive Oxygen Species in Rice Fields: A Review of Generation Mechanisms, Influencing Factors and their Environmental Impacts - Yingxue Yu; Wentao Yang; Yonglin Chen; Hongyan Liu; Tao Jiang; Jian Zhu; Liyu Yang; Pan Wu (Water, Air, & Soil Pollution, 2025)

Critical Review on Recycling of Erdite/KFeS2 Rods from Waste Sludge as Environmental Functional Materials - Yu Chen; Jiewen Yang; Dongxu Liang; Ying Zhang; Tong Sun; Weilu Yang; Suiyi Zhu; Xinfeng Xie; Temuujin Jadambaa (Water, Air, & Soil Pollution, 2025)

Effects of Multi-Step-Ahead Prediction Strategies on LSTM-Based Runoff Prediction - Jingchao Jiang; Yang Gao; Jiaqi Chen; Jingzhou Huang; Juan Yu; Cong Jiang; Junzhi Liu; Anke Xue (Water Resources Management, 2025)

Comparative study of gangue fine aggregate strengthening technologies: microbially induced mineralization, water glass strengthening, and composite strengthening - Chunhua Feng; Linpeng Pan; Ning Li; Yu Chen; Xiaomeng Zhao; Fang Liu; Jianping Zhu; Mingxing Du (Waste Disposal & Sustainable Energy, 2025)

Dehydrochlorination of PVC at low-temperatures and the pyrolysis behavior of dechlorinated PVC - Jiayou Sun; Tianyang Ding; Xue Zhao; Pengcheng Wang; Wen Chen; Jie Yu (Waste Disposal & Sustainable Energy, 2025)

Correction: Combining network Pharmacology and metabonomics to explore the mechanism of baicalin inhibiting PRRSV replication - Qin Luo; Yu-xuan Huang; Hai-rui Li; Chang-hong Qiao; Zhen-wen He; Xiang-yu Chen; Xiao-hu Wang; Gang Wang; Meng-meng Zhao; Ru-jian Cai (Veterinary Research Communications, 2025)

Combining network pharmacology and metabonomics to explore the mechanism of baicalin inhibiting PRRSV replication - Qin Luo; Yu-xuan Huang; Hai-rui Li; Chang-hong Qiao; Zhen-wen He; Xiang-yu Chen; Xiao-hu Wang; Gang Wang; Meng-meng Zhao; Ru-jian Cai (Veterinary Research Communications, 2025)

Genome-Wide Identification and Expression Profiling of Oryza Sativa Sulfotransferase Genes Associated with Oxyfluorfen and Fluroxypyr-Meptyl Metabolism - Li Qing Zeng; Xiao Yu Zhong; Nian Hua Teng; Xu Zhen Shi; Yi Zhuo Wang; Xi Ran Cheng; Ying Yu Zeng; Zhao Jie Chen (Tropical Plant Biology, 2025)

Genome-Enabled Analyses Reveal Roles of Mangrove Homeobox Superfamily in Response to Salinity - Tingting Chen; Xiuxu Ye; Erhui Feng; Yu Zhang; Peng Wang (Tropical Plant Biology, 2025)

Identification and Expression Analysis of Low-Temperature Stress Responsive MIKC-Type MADS-Box Gene Family in Wheat - Zhang Junbao; Chen Yushu; Wang Xuesong; Cao Jiaang; Yang Sen; Shao Qingyi; Yu Mengdi; Jin Zhongmin; Liu Lijie (Tropical Plant Biology, 2025)

High Plasma Sarcosine Levels Are Associated with Decreased Risks of Adverse Outcomes After Ischemic Stroke: A Multicenter Prospective Study - Lulu Sun; Daoxia Guo; Xinyue Chang; Yi Liu; Yu He; Pinni Yang; Mengyao Shi; Jing Chen; Aili Wang; Yonghong Zhang; Jiang He; Tan Xu; et al. (Translational Stroke Research, 2025)

Pluvial flood warnings in a tidally influenced basin enhanced by rainfall–tide compound indicators: Taipei case study - Mei-Ying Lin; Wen-Yih Sun; Huei-Syuan Fu; Chih-Hsin Chang; Wei-Bo Chen; Chieh-Ju Wang; Hsuan-Wei Wang; Yi-Chiang Yu; Yen-Wei Li (Stochastic Environmental Research and Risk Assessment, 2025)

Evaluating drought conditions and predicting return periods with the standard soil moisture index: a three-threshold run theory and GH copula approach - Jun Zhao; Yu Liu; Xiaodong Wang; Jinchao Xu; Nuo Chen; Min Liu; Yuhan Zhao; Sadashiv Chaturvedi (Stochastic Environmental Research and Risk Assessment, 2025)

Gamma-selinene synthase catalyzes the first step of dihydroagarofuran sesquiterpene alkaloid biosynthesis in Tripterygium - Xin-Yue Liu; Yu-Fei Li; Jun-Zhe Zhou; Jin-Quan Huang; Ling-Jian Wang; Lei Yang; Chen-Yi Li; Xin Fang; Xiao-Ya Chen (Science China Life Sciences, 2025)

Golgi-associated TRAF6 as a regulator of protein convertase FURIN for insulin receptor precursor processing - Minjun Liu; Kun Zhou; Yang Sheng; Wen Zhang; Qiaoli Chen; Ziyue Chen; Xinyu Yang; Yuxin Jin; Fangtong Liu; Yinqiu Mu; Shu Su; Weikuan Feng; et al. (Science China Life Sciences, 2025)

Decades’ progress and prospects on maize functional genomics and molecular breeding - Qing Li; Jinsheng Lai; Jian Chen; Lin Li; Weibin Song; Beibei Xin; Hainan Zhao; Yingjie Xiao; Feng Tian; Gang Li; Yameng Liang; Lei Liu; et al. (Science China Life Sciences, 2025)

Uncovering the gut microbiome and antibiotic resistome of mammals on the Tibetan Plateau - Chen Tian; Zecheng Tang; Xiaoyu Zhang; Xueqin Yao; Yitian Li; Daohua Zhuang; Yu Luo; Teng Li; Liyan Bai; Fangfang Zhao; Lei Zhu; Guolin Shi; et al. (Science China Life Sciences, 2025)

Carbon isotope excursions in the Ediacaran carbonate strata: Insights from deep-shallow carbon cycle coupling - Yongsheng Liu; Pengfei Xi; Detao He; Chunfei Chen; Kaizhang Yu; Wei Chen (Science China Earth Sciences, 2025)

Climatic and human drivers of spatio-temporal trends in Holocene carbon accumulation in Chinese peatlands - Minghua Zhao; Zhiguo Rao; Yunxia Li; Chaozhu Li; Zixian Feng; Zicheng Yu; Fahu Chen (Science China Earth Sciences, 2025)

Eddies regulate the variability in Argentine shortfin squid distribution and abundance in the southwest Atlantic Ocean - Lichuan Zhang; Kai Zhu; Wenbin Zhu; Bing Kang; Pengchao Jin; Qinwang Xing; Xinjun Chen; Wei Yu (Reviews in Fish Biology and Fisheries, 2025)

Ginsenoside Rg1 alleviates PCPA-induced insomnia by inhibiting NLRP3 inflammasome activation and pyroptosis through the Nrf2/HO-1 pathway in mice - Jingyi Li; Xiufeng Wang; Yu Zhang; Min Wei; Jianqiang Qi; Dan Liu; Runhua Wu; Qin Chen; Junshan Huang (Psychopharmacology, 2025)

Effects of Heat-Killed Probiotic Strains on Biofilm Formation, Transcription of Virulence-Associated Genes, and Prevention of UTIs in Mice - Yueh-Ying Chen; Zhen-Shu Liu; Bo-Yuan Chen; Hon-Man-Herman Tam; Wei-Yau Shia; Hsin-Hsuan Yu; Po-Wen Chen (Probiotics and Antimicrobial Proteins, 2025)

Synbiotic Effects of Lacticaseibacillus paracasei K56 and Prebiotics on the Intestinal Microecology of Children with Obesity - Pengwei Zhang; Xianhui Dong; Yijun Zeng; Junkui Chen; Sijia Yang; Peipei Yu; Chunhong Ye; Wei-Lian Hung; Qiuyue Jiang; Wen Zhao; Zhaozhong Zeng; Jinjun Li; et al. (Probiotics and Antimicrobial Proteins, 2025)

Genome-Wide Identification and Characterization of the Trihelix Transcription Factor Family in Polygonatum kingianum and Gene Expression Pattern Analysis Under MeJA Treatment - Chun-Yu Chen; Wan-Bo Ding; Hong-Jing Zhang; Yan-Ran Qi; Wen-Xiang Wang (Plant Molecular Biology Reporter, 2025)

Phylogenomic Analysis of WD40 Gene Family and the Association with Anthocyanin Biosynthesis in Lagerstroemia indica - Mingzhu Bai; Mengmeng Chen; Mengxin Yu; Guozhe Zhang; Yu Zhao; Qingqing Ma; Liyuan Yang; Cuihua Gu (Plant Molecular Biology Reporter, 2025)

Mowing intensifies plant phosphorus limitation and phosphorus acquisition regulation under N fertilization in the temperate alkaline meadow - Haoran Fu; Jibo Shi; Xiaoying Chen; Yu Tian; Yingxin Huang; Guangdi Li; Qiang Li (Plant and Soil, 2025)

Transcription factor PsnERF1 regulates leaf morphological development in poplar - Zelin Li; Yiran Wang; Yu Qi; Song Chen; Yuqi Liu; Gaofeng Fan; Wenbo Zhang; Su Chen (Plant Cell, Tissue and Organ Culture (PCTOC), 2025)

The nutritional value, application status and challenges of Houttuynia cordata Thunb (H. cordata) - Xiaolin Huang; Peng Yu; Yinghua Luo; Ziyuan Guo; Zihan Wang; Chen Ma; Li Dong; Peng Luo; Guoze Wang; Xiaosong Hu; Fang Chen; Hao Guo; et al. (Phytochemistry Reviews, 2025)

Characteristic ‘Pattern of Autofluorescence’ of the Fingernails and Certain Skin’s Positions is a Novel Diagnostic Biomarker for Acute Ischemic Stroke: A Preliminary Study - Danhong Wu; Mingchao Zhang; Yue Tao; Yujia Li; Haibo Yu; Shufan Zhang; Yufan Luo; Tianqing Chu; Xin Chen; Weihai Ying (Phenomics, 2025)

Metabolomics Reveals Reasons for the Efficacy of Acupuncture in Migraine Patients: The Role of Anaerobic Glycolysis and Mitochondrial Citrate in Migraine Relief - Zishan Gao; Xianzhong Yan; Rui Wang-Sattler; Marcela Covic; Guang Yu; Feifei Ge; Jia Lin; Qin Chen; Juan Liu; Sapna Sharma; Sophie Molnos; Brigitte Kuehnel; et al. (Phenomics, 2025)
Acupuncture is used worldwide to treat migraine, but its scientific mechanism remains unclear. Here, we report a 1 H NMR metabolomics study involving 40 migraine patients and 10 healthy individuals randomly receiving acupuncture or sham acupuncture, followed by machine learning techniques and functional analysis. We found that acupuncture at acupoints particularly enhanced anaerobic glycolysis and modified mitochondrial function by adjusting the levels of plasma pyruvic acid ( p = 0.012), lactic acid ( p = 0.031) and citrate ( p = 0.00079) at a Bonferroni-corrected level of significance compared to the pre-treatment level of these three metabolites in migraine patients. Therefore, acupuncture supplies energy to migraine patients and relieves migraine attacks. In contrast, we observed that sham acupuncture may partially supply energy to migraine patients through lipid metabolism by changing the levels of plasma lipid ( p = 0.0012), glycerine ( p = 0.021), and pyruvic acid ( p = 0.047) at a Bonferroni-corrected level of significance. The functional network analysis further indicates this different way of supplying energy contributes to the different effects of acupuncture and sham acupuncture. Our findings reveal novel metabolic evidence for the specific effect of acupuncture in relation to sham acupuncture. This metabolic evidence could enlighten a brand new direction into acupuncture analgesia mechanism, which in turn would pose fresh challenges for future acupuncture research.

Evaluation of sea-level variability in three oceanic reanalysis products over the East China sea - Mengrong Ding; Yong Jiang; Yujie Han; Yujie Chen; Zipeng Yu (Ocean Dynamics, 2025)

CDK5-Induced HCN2 Channel Dysfunction in the Prelimbic Cortex Drives Allodynia and Anxiety-Like Behaviors in Neuropathic Pain - Lu Chen; Shuai Cao; Yun-Ze Liu; Qi-Fan Yang; Jin-Yu Yang; Dan-Yang Zhang; Guo-Guang Xie; Xiang-Sha Yin; Ying Zhang; Yun Wang (Neuroscience Bulletin, 2025)

GZR101, a Novel Premixed Insulin for the Treatment of Diabetes Mellitus - Wei Chen; Cheng Cui; Wancai Xing; Yining Zhang; Anshun He; Yue Wang; Yan Huang; Nannan Zhai; Qimin Shi; Fangkai Xue; Yongchun Wang; Jun Zhang; et al. (Naunyn-Schmiedeberg's Archives of Pharmacology, 2025)

Chicago Sky Blue 6B modulates MAPK/NF-kB pathway in rat knee osteoarthritis - Yejin Zhang; Weiqing Li; Yu Bai; Hehuan Lai; Jiawei Fang; Lin Ye; Dengwei He; Zhenzhong Chen (Naunyn-Schmiedeberg's Archives of Pharmacology, 2025)

Geological Target Recognition Method Based on Multi-mode Adaptive Prediction System: Algorithms and Applications - Pengfei Lv; Weiying Chen; Yu Zou (Natural Resources Research, 2025)

Ginger-derived 1-(4’-hydroxy-3’-methoxyphenyl)-5-methoxydecan-3-one (HMPM) induces apoptosis and DNA damage against triple-negative breast cancer cells in vitro - Min-Yu Lee; Wan-Ling Tseng; Zong-Ying Yang; Tsu-Ming Chien; Chien-Chih Chiu; Yi-Hao Lo; Chung-Yi Chen; Hsueh-Wei Chang (Molecular Biology Reports, 2025)

Naringin mitigates liver damage in a tissue-engineered liver of metabolic dysfunction-associated steatotic liver disease model by promoting autophagy via the mTOR-ULK1 pathway - Jihui Jia; Yizhi Zhang; Jing Lin; Zhongping Duan; Yu Chen; Xiaohui Zhang (Molecular Biology Reports, 2025)

Role of N6-methyladenosine methylation in transverse aortic constriction-induced cardiac fibrosis: insights from MeRIP-seq analysis - Shidong Liu; Hongxu Liu; Qiyuan Bai; Zhili Wei; Pengying Zhao; Hao Chen; Bing Song; Cuntao Yu (Molecular Biology Reports, 2025)
This study aimed to investigate the role and potential mechanisms of N6-methyladenosine (m6A) methylation in a mouse model of transverse aortic constriction (TAC)-induced cardiac fibrosis using MeRIP-seq. A TAC-induced cardiac fibrosis mouse model was established, and cardiac function and structural parameters were assessed by echocardiography four weeks post-surgery. The global m6A methylation levels in myocardial tissues were evaluated using Dot blot analysis, and the expression levels of m6A-modifying enzymes (METTL3, METTL14, ALKBH5, FTO) were detected by qPCR and Western blot. Additionally, methylated RNA immunoprecipitation sequencing (MeRIP-Seq) was performed to identify differentially methylated sites, followed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses to determine the biological functions and signaling pathways of m6A-methylated genes. The results showed that TAC surgery successfully induced a cardiac fibrosis model in mice, as indicated by significantly reduced EF and LVEF and increased LVIDd and LVIDs. Moreover, m6A methylation levels were elevated in myocardial tissues of TAC mice, accompanied by upregulation of METTL3 and METTL14 expressions and downregulation of ALKBH5 and FTO expression. MeRIP-seq revealed that m6A peaks were primarily enriched in the 3’ UTR regions, with 1,466 differentially methylated sites identified between TAC and sham groups, including 717 hypermethylated and 749 hypomethylated sites. Functional enrichment analyses showed that these differentially methylated genes were involved in various biological processes, including signal transduction, transcriptional regulation, and ion channel activity, and were associated with pathways such as type 2 diabetes mellitus, signaling pathways regulating pluripotency of stem cells, and insulin signaling. Thus, our findings suggested that m6A methylation played a significant role in TAC-induced cardiac fibrosis by regulating key genes involved in myocardial remodeling and functional impairment.

Molecular hydrogen attenuates cisplatin-induced nephrotoxicity by modulating β-hydroxybutyrate metabolism - Yan Tian; Huilan Su; Yunxi Chen; Xiaomeng Geng; Yafang Zhang; Yu Wang; Wenjie Tang; Weiping Fan; Jianjun Zhou; Youzhen Wei (Molecular Biology Reports, 2025)

Thymus serpyllum extract exerts anticancer activities against colorectal cancer by modulating metastasis, cell cycle arrest, and apoptosis - Chao-Yuan Yao; Kai-Fu Chang; Ju-Huei Chien; Xiao-Fan Huang; Yu-Chi Chen; Ming-Chang Hsieh; Nu-Man Tsai (Molecular Biology Reports, 2025)

Interplay between Nrf2 and ROS in regulating epithelial-mesenchymal transition: implications for cancer metastasis and therapy - Yi Xu; Shuning Hu; Rui Chen; Sheng Xu; Guangyang Yu; Lili Ji (Molecular Biology Reports, 2025)
Epithelial-mesenchymal transition (EMT), including developmental (Type I), wound healing (Type II), and pathological (Type III) subtypes, constitutes a critical driver of cancer metastasis. This review analyzes the redox interplay between nuclear factor erythroid 2-related factor 2 (Nrf2) and reactive oxygen species (ROS) in EMT regulation and cancer progression. Nrf2 maintains redox homeostasis through antioxidant gene activation while paradoxically promoting tumor survival and drug resistance via Keap1-dependent degradation and phosphorylation-mediated stabilization. ROS generated through mitochondrial and NADPH oxidase pathways exhibit dual functionality: moderate levels activate EMT transcription factors to drive metastasis and cancer stem cells (CSCs) plasticity, whereas excessive ROS induce apoptosis and ferroptosis. While Nrf2 typically suppresses EMT through ROS neutralization and epithelial integrity preservation, chronic Nrf2 activation in CSCs paradoxically sustains metastatic potential through redox buffering. This synthesis delineates the spatiotemporal regulation of Nrf2-ROS-EMT networks across tumor microenvironments, emphasizing therapeutic opportunities through redox balance modulation and pathway-specific Nrf2 inhibition in advanced malignancies.

Correction: Regulatory effect of AMP-activated protein kinase on pulmonary hypertension induced by chronic hypoxia in rats: in vivo and in vitro studies - Xiaoying Huang; Rong Fan; Yuanyuan Lu; Chang Yu; Xiaomei Xu; Xie Zhang; Panpan Liu; Shuangquan Yan; Chun Chen; Liangxing Wang (Molecular Biology Reports, 2025)

Expression of thrombomodulin in pterygium: implications for inflammation and disease progression - Yu-Kuei Lee; Chun-Chieh Lai; I-Chen Peng; Yi-Hsun Huang (Molecular Biology Reports, 2025)

Phenotypic and molecular characterization of a recurrent SPTAN1 mutation causing SPG91 - Shih-Chun Lan; Ming-Der Perng; Yung-Yee Chang; Ying-Fa Chen; Min-Yu Lan (Molecular Biology Reports, 2025)

Antioral cancer effects of ginger derivative 3-HDM exert oxidative stress-associated apoptosis and DNA damage - Kuan-Liang Chen; Hsin-I Lu; Ching-Yu Yen; Chung-Yi Chen; Tsu-Ming Chien; Jiiang-Huei Jeng; Bing-Hung Chen; Hsueh-Wei Chang (Molecular Biology Reports, 2025)

FADS2 inhibits colorectal cancer cell proliferation by regulating ferroptosis through SLC7A11/GPX4 - Qinghui Yang; Hao Zhang; Jing Luo; Hongmei Yu; Xiaodi Yang; Chen Wang (Molecular Biology Reports, 2025)

Molecular cloning, expression, and bioinformatics analysis of the CueO laccase gene from Escherichia coli SDB2 - Hui Deng; Sicong Li; Yanling Huang; Jiangling Li; Qingsong Ni; Yang Zhao; Jin Chen; Xiurong Peng; Bin Li; Dan Yu (Molecular Biology Reports, 2025)

New insights into tRNA-derived small RNAs in human digestive diseases - Yong-qiang Liu; Feng Chen; Fa Zhang; Yuan-mei Ye; Yu-jie Su; Ya-tao Liu; Yu-fang Leng (Molecular Biology Reports, 2025)

YAP/TAZ as master regulators in liver regeneration and disease: insights into mechanisms and therapeutic targets - Bingyu Ye; Meijuan Yue; Hu Chen; Caifang Sun; Yongle Shao; Qinpeng Jin; Chunyan Zhang; Guoying Yu (Molecular Biology Reports, 2025)

RNA methylation and breast cancer: insights into m6A, m7G and m5C - Yuhan Dai; Shuhan Zhao; Huilin Chen; Wenxin Yu; Ziyi Fu; Yangyang Cui; Hui Xie (Molecular Biology Reports, 2025)

Moderate-intensity aerobic exercise inhibits cell pyroptosis to improve myocardial ischemia-reperfusion injury - Yu Wang; Yushan Li; Chaofan Chen; Hailong Zhang; Weili Liu; Chao Wu; Haonan Chen; Ran Li; Jinghan Wang; Yingchao Shi; Shengfang Wang; Chuanyu Gao (Molecular Biology Reports, 2025)

Araloside A Induces Raf/MEK/ERK-Dependent Autophagy to Mitigate Alzheimer’s and Parkinson’s Pathology in Cellular and C. elegans Models - Xue Chen; Xing-Yue Zhou; Cai Lan; Hai-Jun Fu; Zhi-Chao Li; Meng-Yi Chen; Yong-Ping Wen; Lu Yu; Da-Lian Qin; An-Guo Wu; Jian-Ming Wu; Xiao-Gang Zhou (Molecular Neurobiology, 2025)

Melatonin Attenuates Spinal Cord Injury by Regulating Ferroptosis Through the Nrf2/HO-1/GPX4 Pathway - Zhengxi Yu; Dingwei Wu; Tengbin Shi; Dehui Chen; Hao Feng; Huina Chen; Hailin Lin; Lei Sun; Wenge Liu (Molecular Neurobiology, 2025)

PET Imaging Unveils Neuroinflammatory Mechanisms in Psychiatric Disorders: From Microglial Activation to Therapeutic Innovation - Yu-dan Liu; Yi-heng Chang; Xue-ting Xie; Xin-yao Wang; Hao-yan Ma; Mei-chen Liu; Hui-min Zhang (Molecular Neurobiology, 2025)

Performance comparison of germline variant calling tools in sporadic disease cohorts - Qiaofeng Song; Jinglan Zhai; Changshui Chen; Haibo Li; Aihua Cao; Bo Yuan; Yu An (Molecular Genetics and Genomics, 2025)

Prevalence and spectrum of STRC variants in 1015 sensorineural hearing loss patients: insights from the Chinese population - Luo Guo; Sha Yu; Wenrui Zhao; Liheng Chen; Guiqing Cheng; Weitao Li; Wei Li; Haiting Ji; Shan Sun; Huiqian Yu; Haiying Liu; Chunyi Gui; et al. (Molecular Genetics and Genomics, 2025)

Genetic analysis of patients with low-frequency non-syndromic hearing loss - Sha Yu; Weitao Li; Xinhao Lin; Liheng Chen; Wenxia Chen; Luo Guo; Yilai Shu (Molecular Genetics and Genomics, 2025)

Reductive coupling of 2,2'-dinitrobiphenyls into benzo[c]cinnolines with NaHS - Pingbing Yu; Zhaoyue Wen; Chun Wang; Jianlian Wu; Tie-Gen Chen; Wei Chen (Molecular Diversity, 2025)

Impact of vancomycin and Clostridioides difficile on the secretome and pathogenicity of Clostridium innocuum - Yi-Ywan M. Chen; Kun-Yi Chien; Hui-Ru Shieh; Cai-Jie Luo; Yu-Xun Chang; Chuan Chiang-Ni; Chih-Ho Lai; Cheng-Hsun Chiu (Medical Microbiology and Immunology, 2025)

Dose-dependent M2 macrophage polarization induced by Talaromyces marneffei promotes lung cancer cell growth via arginine-ornithine-cycle activation - Anqi Chen; Qian Yu; Leliang Zheng; Junqi Yi; Ziying Tang; Huabo Ge; Yue Ning; Na Yin; Yaohuan Xie; Shengnan Chen; Wenhua Shi; Xiaoling She; et al. (Medical Microbiology and Immunology, 2025)

Multi-omics dissection of RAD21-PON1 axis reveals metabolic-immune crosstalk and prognostic significance in hepatocellular carcinoma - Zhe Liu; Fang Liu; Zhongyu Yao; Yun Long; Nanjun Chen; Jixiang Yu; Lei Wang; Yang Wang; Ka-Chun Wong (Mammalian Genome, 2025)

Flooding-drainage regulates arsenic transformation and its associated microbial dynamics in paddy soil amended with ferrihydrite - Shaopeng Jia; Jianbo Chen; Yujuan Fang; Xiu Yi; Manjia Chen; Yining Gao; Huanyun Yu; Chengshuai Liu; Hui Tong (Journal of Soils and Sediments, 2025)

Integrated source apportionment, migration analysis, and probabilistic risk assessment of trace metals in soil–groundwater systems at an informal landfill - Mengqi Liu; Siyuan Chen; Xueyan Yu; Congcong Sun; Xiaofei Yan (Journal of Soils and Sediments, 2025)

Application of Urea Phosphate to Increase Soil Phosphorus Supply Intensity, Maize yield, and Phosphate Fertilizer Utilization Efficiency in Saline-Alkaline Soil - Guiting Yang; Yuezhuo Zhuang; Zhiguang Liu; Min Zhang; Yu Wang; Ming Zhang; Qi Chen (Journal of Soil Science and Plant Nutrition, 2025)

Biochar-Amended Composting Transforms Chicken Manure Waste Into a Resource: Enhancing Extra-Rhizosphere Soil Fertility and Shaping Microbial Communities - Longjun Chen; Haiping Fan; Lulong Zhong; Yuncai Wang; Cheng Chen; Xin Chen; Yanping Chen; Jiaolin Zhang; Yu Lin (Journal of Soil Science and Plant Nutrition, 2025)
This study elucidates the synergistic regulatory mechanisms of biochar-amended chicken manure and mushroom residue compost (BCM) on soil microbial communities and nutrient cycling in the extra-rhizosphere, while evaluating its potential for sustainable agricultural waste recycling. Methods: We conducted a 50-day composting trial using five biochar application rates (0–7%). Assessed parameters included compost maturity (C/N ratio), nutrient content (NO 3 − -N, available phosphorus [AP], soil organic matter [SOM]), phosphatase and catalase activities, microbial community composition, and metabolic pathways. We performed Redundancy analysis (RDA) to correlate SOM/AP dynamics with microbial diversity and functional pathways. Results: At 5–7% biochar, compost maturity improved significantly, with C/N ratios of 15.6–18.2 and 2.2-4.0-fold increases in NO 3 − -N (1.41 mg/g), AP (50.09 mg/kg), and SOM (166.11 g/kg). Enzymatic activities (phosphatase: 9.81 mg/g·24 h; catalase: 83.08 µmol/g·24 h) correlated strongly with SOM/AP (R 2 = 0.71–0.82). Biochar enriched Proteobacteria (34.1%) and Actinobacteriota (15.2%), suppressed Halophiles ( Halomonas reduced by 52%), and enhanced carbon metabolism and oxidative phosphorylation pathways. RDA identified SOM/AP as a key driver of microbial diversity (R 2 = 0.91). The 5% biochar dose optimized nutrient retention (37–59% increases in AP, Available potassium [AK], NO 3 − -N) while maintaining microbial diversity, outperforming higher doses. Conclusions: This study demonstrates biochar’s dual role in reshaping extra-rhizosphere microbial ecology and nutrient dynamics, offering a precision agriculture strategy for sustainable waste recycling and circular economy practices. The 5% biochar dosage proved optimal, enhancing nutrient cycling and microbial activity while mitigating halophilic microbial suppression. Graphical Abstract

Predicting and Optimizing Cotton Yield and Nitrogen-Phosphorus Fertilization Using the DSSAT Model and Ecological Stoichiometry Theory - Zhuo Yu; Meiwei Lin; Yi Chen; Xiaoju He; Kai Lu; Kairui Wen; Weihong Sun; Weiguo Fu (Journal of Soil Science and Plant Nutrition, 2025)

Correction: Nitrogen Supply Shapes the Nitrogen Cycling Microbiome in Sorghum Intercropped with Peanut - Xiaolong Shi; Pei Guo; Xia Shao; Yuxuan Chen; Chang Liu; Chunjuan Liu; Haiqiu Yu; Hongtao Zou; Yufei Zhou (Journal of Plant Growth Regulation, 2025)

Nitrogen Supply Shapes the Nitrogen Cycling Microbiome in Sorghum Intercropped with Peanut - Xiaolong Shi; Pei Guo; Xia Shao; Yuxuan Chen; Chang Liu; Chunjuan Liu; Haiqiu Yu; Hongtao Zou; Yufei Zhou (Journal of Plant Growth Regulation, 2025)

Physiological and transcriptomic responses of attached-cultivated Arthrospira platensis to heat stress - Wen Liu; Lu Li; Youzhi Yu; Zhihui Li; Lin Chen; Tianzhong Liu (Journal of Applied Phycology, 2025)

TiO2-Doped Fe-Tailings Heterogeneous Catalysts: Engineering Synergistic Photocatalytic-Fenton Pathways for High-Efficiency Phenol Mineralization - Wen-hao Zhang; Yu Wei; Qi Yu; Chun-heng Wang; Xue-fei Lei; Shao-hua Luo; Huan-huan Chen; Wen-ning Mu (International Journal of Environmental Research, 2025)

Lung epithelial injury impairs early host immune responses to Mycobacterium tuberculosis - Xuan Miao; Xue Li; Zuokuan He; Guiying Xu; Yu Li; Youwei Wang; Junping Wu; Qi Wu; Huaiyong Chen (Inflammation Research, 2025)

Early hyperferritinemia in polytrauma: a biomarker of systemic inflammation and mortality risk in a multicenter cohort study - Shunyao Chen; Teding Chang; Jialiu Luo; Cong Zhang; Peidong Zhang; Shuaipeng Gu; Zhiqiang Lin; Yujie Chen; Youxie Shen; Liming Dong; Qian Wan; Liang He; et al. (Inflammation Research, 2025)

Interleukin-37 modulates microglial phenotype and inhibits inflammatory response via the MyD88/NF-κB pathway in lipopolysaccharide-induced neuroinflammation - Jingwen Zhang; Muhammad Abid Hayat; Yu Si; Tao Guo; Yinying Ni; Qian Wang; Yancheng Hong; Yudie Cao; Sijia He; Zijuan Weng; Fengmei Li; Hao Zuo; et al. (Inflammation Research, 2025)

The causal effect of natural killer cells on COVID-19 infection, hospitalization and severity - Kaili Yang; Jun Quan; Zhi Liu; Zebing Huang; Shuyi Wang; Jia Li; Aiming Wang; Li Wu; Songman Yu; Panpan Yi; Meifang Xiao; Yayu Chen; et al. (Inflammation Research, 2025)

IL-33, a neutrophil extracellular trap-related gene involved in the progression of diabetic kidney disease - Yufei Ye; Anwen Huang; Xinyan Huang; Qin Jin; Hongcheng Gu; LuLu Liu; Bing Yu; Longyi Zheng; Wei Chen; Zhiyong Guo (Inflammation Research, 2025)

Pivotal epitopes for islet antigen-specific CD8+ T cell detection improve classification of suspected type 1 diabetes with the HLA-A*0201 allele - Yang Chen; Min Shen; Yong Gu; Xinyu Xu; Lingling Bian; Fan Yang; Shuang Chen; Li Ji; Jin Liu; Jing Zhu; Zheng Zhang; Qi Fu; et al. (Immunologic Research, 2025)

Lithospermic acid targeting heat shock protein 90 attenuates LPS-induced inflammatory response via NF-кB signalling pathway in BV2 microglial cells - Jie Guo; Chen-guang Li; Feng-yi Mai; Jing-rong Liang; Ze-hao Chen; Jiao Luo; Ming-chao Zhou; Yu-long Wang; Wen-tao Yang (Immunologic Research, 2025)

Acute systemic inflammation induces region-specific morphological remodeling of astrocytes and microglia concurrent with depression-like behavior - An-Qi Zhang; Meng-Meng Zhang; Ling-Jie Li; Mei-Xue Yuan; Rong-Yu Liu; Peng Chen; Chen-Wei Wang; Yu Wang; Jiang-Ning Zhou; Qing-Hong Shan; Xin-Ya Qin (Histochemistry and Cell Biology, 2025)

Blocking triggering receptors expressed on myeloid cell-1 alleviates alveolar epithelial cell senescence by inhibiting oxidative stress in pulmonary fibrosis - Wen-Jing Zhong; Jian-Bing Xiong; Chen-Yu Zhang; Ling Jin; Nan-Shi-Yu Yang; Han-Xi Sha; Yu-Biao Liu; Jia-Xi Duan; Cha-Xiang Guan; Yong Zhou; Feng Su (Histochemistry and Cell Biology, 2025)

Enhancing Laterite’s Mechanical Properties and Reducing Water Sensitivity with Glycerol Monostearate - Kun-Yu Fu; Yan-Ge Chen; Ying-Zhen Ji; Qi-Ya Wang (Geotechnical and Geological Engineering, 2025)

Desiccation Cracking Behavior of Weathered Red-Layer Mudstone: Influence of Temperature and Layer Thickness - Yuqing Zhou; Xiaobin Chen; Jiasheng Zhang; Zhaosheng Yu (Geotechnical and Geological Engineering, 2025)

Comparative chloroplast genomic analysis: uncovering variations and phylogenetic relationships in tea plants from Shaoyang, Hunan Province, China - Jin Li; Yu Qin; Jun Tang; Xiao-Yan Qiu; Chang-Qing Xie; Han Tang; Ai-Ming Tang; Xiao Chen; Jun-Ping Xie; Hua Luo (Genetic Resources and Crop Evolution, 2025)

Identification, characterization, and expression profiling of putrescine synthesis genes associated with bentazone metabolism in Oryza sativa - Li Qing Zeng; Nian Hua Teng; Ying Yu Zeng; Zhi Jiang He; Yi Zhuo Wang; Zhi Zhong Zhou; Xiao Liang Liu; Xi Ran Cheng; Zhao Jie Chen (Genetic Resources and Crop Evolution, 2025)

Identification, characterization, and expression profiling of rice MADS-box transcription factor genes associated with fluroxypyr-meptyl and oxyfluorfen metabolism - Zhi Zhong Zhou; Nian Hua Teng; Jia Lin Liang; Ying Yu Zeng; Yi Zhuo Wang; Li Qing Zeng; Xiao Liang Liu; Xi Ran Cheng; Zhao Jie Chen (Genetica, 2025)

Comparative analysis of chloroplast genomes of Loropetalum chinense and its purplish-red-flowered variety - Lilin Chen; Yu Song; Zhiyong Zhang; Huimin Li (Functional & Integrative Genomics, 2025)

DNA methylation in plant heterosis: mechanisms and prospects - Dan Wang; Xinrui Tang; Chaoguan Yu; Jianfeng Hua; Tingting Chen; Yinfeng Xie (Functional & Integrative Genomics, 2025)

Integrative genomics and genetics from evolutionary insights to precision breeding in peanuts (Arachis Hypogaea L.) - Muhammad Jawad Umer; Lu Huang; Hao Liu; Raufa Batool; Haifen Li; Shaoxiong Li; Yanbin Hong; Runfeng Wang; Qianxia Yu; Qing Lu; Rajeev K. Varshney; Xiaoping Chen (Functional & Integrative Genomics, 2025)

Discovering novel type I collagen fragments from Cyprinus carpio supporting bone regeneration - Jianhua Zeng; Miao Chen; Xinglong Wang; Huan Yu; Liang Zhang; Yongxing Peng; Ping Wan; Zhongshi Huang; Fuqiang Ma; Jingtang Li (Functional & Integrative Genomics, 2025)

Transcriptomic profiling reveals mechanism, therapeutic potential, and prognostic value of cancer stemness characteristic in nasopharyngeal carcinoma - Jin-Wei Chen; Run-Nan Shen; Jiang-Quan Zhu; Ying-Hang Wang; Liang-Min Fu; Yu-Hang Chen; Jia-Zheng Cao; Jin-Huan Wei; Jun-Hang Luo; Jia-Ying Li; Cheng-Peng Gui (Functional & Integrative Genomics, 2025)

Effects of MS-222 on the physiological and biochemical response, histomorphology, gut microbiota, and flesh quality in largemouth bass (Micropterus salmoides) - Ping Gao; Rimeng Chen; ShanShan Lin; Haodong Yu; Xuezhen Zhang (Fish Physiology and Biochemistry, 2025)

Formation mechanism and health risk assessment of high fluoride geothermal water in Gonghe Basin, Northwest China - Jianqiang Chen; Zhen Wang; Yongge Li; Haiyan Liu; Yu Yang; Narsimha Adimalla; Chuanshun Zhi; Bo Wang (Environmental Geochemistry and Health, 2025)

Investigation on the enrichment and partitioning of triclosan (TCS) in aquatic-sedimentary-multispecies plant systems - Li Hua; Gaofan Dai; Yu Chen; Linfeng Li (Environmental Geochemistry and Health, 2025)

Discrimination between focal epilepsy and generalized epilepsy based on the spatial patterns of EEG network - Chunli Chen; Yi Liang; Guan Zhou; Shiyun Xu; Cheng Li; Jixuan Zhou; Lian Luo; Dezhong Yao; Peng Xu; Fali Li; Liang Yu (Cognitive Neurodynamics, 2025)

Aberrant dynamics of the default mode network activity in patients with obsessive-compulsive disorder - Yan Cui; Hui Lei; Shuang Yu; Ke Chen; Yang Xia; Ruxiang Xu; Daqing Guo; Xiongzhao Zhu; Dezhong Yao (Cognitive Neurodynamics, 2025)

Research on hybrid modelling techniques for complex karst geology - Hu Song; Qingru Yu; Linjun Qu; Yan Zhang; Mintao Ou; Yangyang Chen; Wen Liu (Carbonates and Evaporites, 2025)

Study on the mechanism of shallow damage to expansive soil slopes induced by preferential crack flow infiltration - Xiao-hu Huang; Zhao-heng Wei; Jian-wei Chen; Yu-huang Xiao (Bulletin of Engineering Geology and the Environment, 2025)

Ecological risk assessment for Cry1Da_7, Cry1B.3 and Vip3Cb1 proteins expressed in MON 89151 cotton: an insect-protected cotton with targeted activity against Lepidoptera - Harit K. Bal; Collin J. Preftakes; Lawrence Long; Carlos J. Esquivel; Frankie Stubbins; Chitvan Khajuria; Jianguo Tan; David Dyck; Brent Werner; Justin Ungerer; Bingyao Li; Yu Liu-Gontarek; et al. (Transgenic Research, 2025)

Competent expression of effective and long-acting human α-Gal A-Fc fusion protein in the milk of transgenic mice - Mengke Yuan; Lan Yang; Chunyang Li; Zhiqiang Wu; Zhipeng Liu; Tianfei Du; Xinzong Rong; Cong Cong; Yongxia Zhang; Xiaoping Yu; Yali Gao; Zhengli Chen; et al. (Transgenic Research, 2025)

Long-term tea cultivation degrades soil health: Insights from microbial structure and function in tea gardens - Xinyi Chen; Mengqi Lin; Zhenghao Wu; Lei Yu; Qingxue Guo (Soil Ecology Letters, 2025)

Transcriptome analysis reveals the regulation of PhAN2 on PhANS, PhRT and PhAN9 in petunia - Yi Yao; Wenjie Yang; Wenqi Deng; Zeyu Chen; Weiyuan Yang; Juanxu Liu; Yixun Yu (Plant Biotechnology Reports, 2025)

Dynamic characteristics of large-scale ice avalanches under the effect of frictional heat - Yu Luo; Qiang Chen; Lei Zhu; Tengfei Yan (Journal of Mountain Science, 2025)

Microscopic Differences and Connectivity Evaluation for Typical Unconsolidated Sandstone Gas Reservoirs in the South China Sea: A Case Study from Lingshui A Area, Qiongdongnan Basin - Di Meng; Yiqiang Li; Chong Zhang; Xiaoyu Tang; Ning Zhao; Wei Zhou; Jian Chen; Yu Sun (Journal of Ocean University of China, 2025)

High Survival with Fitness Cost in Marine Copepod Tigriopus japonicus Exposed to the Toxic Dinoflagellate Alexandrium pacificum - Wenzhuo Yu; Yunyun Zhuang; Ning Wang; Jing Wang; Hongju Chen; Guangxing Liu (Journal of Ocean University of China, 2025)

Investigation of Aviation Turbulence in Different Air Traffic Control Zones across China - Jingyuan Shao; Zhenyu Yu; Yi Li; Kaijun Wu; Zhaoyue Zhang; Youfan Chen; Wenhan Gu; Haiwen Liu; Yanyu Leung; Pak-Wai Chan; Jianping Guo; Zibo Zhuang (Journal of Meteorological Research, 2025)

Assessing the impact of upstream water quality levels on downstream economic growth in China: A high-resolution panel study - Yu Ding; Chenglong Wang; Chenyang Shuai; Xi Chen; Jingran Sun; Bu Zhao (Journal of Geographical Sciences, 2025)

Di(2-ethylhexyl) phthalate reduces the ginsenoside content in Panax ginseng root exudates by disrupting rhizosphere microbe-mediated soil nitrogen cycling - Lu Yu-Shun; Li Shan-Shan; Sha Ji-Yue; Chen Jian-Bo; Huo Xiao-Hui; Xu Yan-Yang (Applied Soil Ecology, 2025)

Space self-adaption global variance Reduction(SsGVR) method for large-scale radiation shielding calculation - Jichong Lei; Zhenping Chen; Zhiqiang Peng; Zining Ni; Jun Hong; Hong Hu; Xiaoyong Fang; Cannan Yi; Changan Ren; Muhammad Abdul Wasaye; Tao Yu (Annals of Nuclear Energy, 2025)

Modulation of growth, gut-liver axis, and antioxidant defense by Bacillus tequilensis (GCB-3) in grass carp (Ctenopharyngodon idella) under high-carbohydrate diet: Insights into health enhancement and oxidative stress mitigation - Xin Wang; Dongming Zhang; Xinping Zhang; Xinyu Lei; Dan Jiang; Lili Lin; Wenli Zhu; Sibu Wang; Quan Huang; Yuxin Li; Yu-ke Chen; Zhixin Guo (Animal Feed Science and Technology, 2025)

Flexible MoS2-based wearable SERS sensor for noninvasive early diagnosis of glutaric acidemia - Qi Liu; Wenrou Yu; Luo Ren; Anping Liu; Zhaoxian Chen; Xuliang Xia; Yuqin Xie; Yingzhou Huang (Analytica Chimica Acta, 2025)

Analytical and usability comparison of microsampling dried blood spot devices for glucocorticoid detection in sports using ultra-high-performance liquid chromatography–tandem mass spectrometry - Cheng-Chia Chen; Yu-En Lin; Mei-Chich Hsu; Yu-Chuan Lin; William Chih-Wei Chang (Analytica Chimica Acta, 2025)

Multi-modal fusion model combines SERS spectroscopy and clinicopathological features to predict neoadjuvant therapy response in breast cancer - Murong Li; Fei Xie; Longfei Yin; Xiongwei Cai; Wenting Yu; Zhaonan You; Tiantian Liu; Lei Chen; Song Yu; Guohua Wu; Shu Wang (Analytica Chimica Acta, 2025)

All-in-one prepared highly stable fluorescent copper nanocluster composite for point-of-care sensing of tetracycline - Ting Zhu; Yu Yang; Yuhui Shang; Yali Liu; Jinyang Chen (Analytica Chimica Acta, 2025)

A novel cucurbit[8]uril-based fluorescent probe for the detection of phenethylamine in urine - Min Chen; Wen Min; Shang-Wei Yuan; Carl Redshaw; Li-Xia Chen; Qiu-Yu Peng; Tao Yang; Zhu Tao; Xin Xiao (Analytica Chimica Acta, 2025)

Development and validation of a five-channel multiplex LC−ESI−MS/MS method for the quantification of carboxylic acids in urine - Wan-Hui Lu; Ju-Yu Chen; Te-I Weng; Ching-Hua Kuo; Guan-Yuan Chen (Analytica Chimica Acta, 2025)

Automatic calibration of the Biome-BGC model with the PEST software to simulate the forest and farmland ecosystems of the Qinling Mountains in China - Kaiyuan Gong; Zhuo Huang; Linsen Wu; Zhihao He; Junqing Chen; Zhao Wang; Qiang Yu; Hao Feng; Jianqiang He (Agricultural and Forest Meteorology, 2025)

Warming enhances productivity despite exacerbated water and nutrient deficits in wild blueberry, a traditionally managed temperate crop - Pratima Pahadi; Yu-Ying Chen; Seanna Annis; Lily Calderwood; Frank Drummond; Jay Wason; Yong-Jiang Zhang (Agricultural and Forest Meteorology, 2025)

Measurement as functional minimization: An image-based method for river surface velocity and discharge estimation - Kailin Huang; Lionel Pénard; Hua Chen; Chong-Yu Xu (Advances in Water Resources, 2025)

Liu Jun Zi Decoction extends lifespan and healthspan through p16/p21 signaling in Caenorhabditis elegans - Xinyi Wang; Lu Zhang; Xiaoyan Gao; Lijun Zhang; Jing Yu; Ying Liu; Minglv Fang; Yingxuan Yan; Liang Chen; Jun Du; Huida Guan; Cheng Huang; et al. (Biogerontology, 2025)

Genetically predicted causal links between gut microbiota and biological aging phenotypes in age-related macular degeneration - Yifan Zhou; Zhenyu Wang; Chen Huang; Xiaotong Yu; Xueyao Cai; Di Zhao; Yuchen Cai (Biogerontology, 2025)

Control of post-harvest soft rot (Rhizopus stolonifer) on sweet cherry using volatile organic compounds produced by Bacillus velezensis Q-84 - Jian-Yu Wang; Min-Xin Mao; Chun-Yan Xu; Man Zou; Wen-Ting Bao; Yi-Ning Zhou; Shun-Qing Hu; Ke-Xin Jiao; Qing-Kun Lu; Peng Zhao; Kun-Peng Zhang; Yi-Lun Chen; et al. (BioControl, 2025)

LncRNA SNHG16 Drives PD-L1-Mediated Immune Escape in Colorectal Cancer through Regulating miR-324-3p/ELK4 Signaling - Zhiyuan Chen; Zhenjuan Wu; Minghao Wu; Yu Zhang; Sha Hou; Xiangyang Wang; Ya Peng (Biochemical Genetics, 2025)

Complete genome sequence of a novel partitivirus identified in Rhizoctonia solani AG-4 HG III isolate Rs31 - Hongyang Chu; Rui Shi; Churong Wu; Wurong Chen; He Liu; Yuyu Zhang; Shuhui Yu; Yuchuan Li; Yanqiong Li (Archives of Virology, 2025)

Pterostilbene feeding experiment on Litopenaeus vannamei: network pharmacology, molecular docking, and physiological enhancement mechanism - Zhengxu Chen; Futao Jing; Tengwen Zhang; Xin Yu; Liwen Liao; Yaobing Li; Yuxin Wen; Luqing Pan (Aquaculture International, 2025)

Integrated Geology-Geophysics Exploration of Rare Metal Deposits in the Yidun Island Arc Collisional Orogen - Rong Yang; Yu Peng; Li Qing; Qian-kun Liu; Xue-feng Hao; Han Wu; Jun-bo Fan; Hong-juan Chen; Tao Yang (Applied Geophysics, 2025)

Simultaneous estimation of Bouguer gravity anomaly and near-surface density using Bayesian approach: A Yunnan case study - Feng-gui Niu; Shi Chen; Yong-bo Li; Hong-lei Li; Yuan-yuan Niu; Yu-hang Pan (Applied Geophysics, 2025)

Numerical Simulation of a Three-Dimensional Strongly Magnetic Material Tensor in Wave Vector Domain - Kun Li; Hui Shi; Yu-cheng Wu; Chen Kang; Zhao-Dongdong (Applied Geophysics, 2025)

Neutrophil CD11b is a pivotal PANoptosis marker correlated with disease activity in antineutrophil cytoplasmic antibody-associated vasculitis - Xiang-Yu Han; Yi-Yang Zhao; Su-Fang Chen; Zhi-Ying Li; Ming-Hui Zhao; Min Chen (Apoptosis, 2025)

Sources and characteristics of different mode aerosols in the Mt. Everest region - Yaowen Lv; Xianjie Cao; Tao Wang; Zeren Yu; Chen Cui; Pengfei Tian; Jiening Liang; Lei Zhang (Air Quality, Atmosphere & Health, 2025)

Adaptive Feeding Strategies Facilitate Resilience of Deep‐Sea Cold Seep Molluscs Confronting Climate Change - Yu Chen; Yali Liu; Jie Li; Haiyan Yu; Junyi Yang; Qiqi Li; Lina Lyu; Si Zhang (Molecular Ecology, 2025)
Molluscs living in dynamic deep‐sea cold seep environments have evolved distinct feeding strategies for survival. Here, we present the chromosome‐level genomes of two sympatric mollusc species with distinct feeding strategies, a symbiosis‐dependent mussel Gigantidas haimaensis and a predatory snail Phymorhynchus buccinoides . Comparative genomic analysis revealed gene family expansions related to the bacterial component degradation (e.g., b4GalT s) in G. haimaensis , suggesting an adaptation to symbiotic life. Conversely, P. buccinoides exhibited gene family expansions associated with appetite regulation (e.g., ox2r ) and the digestive system (e.g., sult1 and chst ), indicating genetic modifications for deep‐sea predation. Furthermore, we conducted an in situ experiment mimicking a scenario in which ocean warming and sea‐level rise resulted in a mass methane leakage in deep‐sea cold seeps. Interestingly, G. haimaensis increased its metabolic rate and exhibited transcriptional responses. However, P. buccinoides suppressed energy production and responses at translational and posttranslational levels, which is compatible with their distinct feeding strategies. Collectively, our results provide insights on the evolutionary basis and resilience mechanisms related to energy management, which may facilitate methane tolerance of molluscs in the deep‐sea cold seeps threatened by climate change.

The Pilot Study on the Histological and Ultrastructural Characteristics of Major Immune Organs (Spleen, Head Kidney, and Trunk Kidney) and Analysis of Pathological Features in Sichuan Taimen ( Hucho bleekeri ) - Qinyao Wei; Hua Li; Yeyu Chen; Zhao Liu; Yanling Chen; Yi Yu; Quanyu Tu; Guiliang Liu; Zhaobin Song; Jun Du; Huanchao Yang (Journal of Fish Diseases, 2025)
Sichuan taimen ( Hucho bleekeri ) is a glacial relict and critically endangered fish species restricted to the Yangtze River drainage in China. The lack of knowledge regarding the morphology of immune organs may limit the timely detection of health threats, thereby hindering effective conservation efforts. To address this gap, the pilot study provides the first histological and ultrastructural characterisation of the main immune organs (spleen, head kidney, and trunk kidney) of H. bleekeri . The spleen comprises red and white pulp; the red pulp is abundant in erythrocytes, while the white pulp contains leukocytes within a reticular network. Melano‐macrophage centers, involved in immune and phagocytic activities, are prominent in the spleen and kidneys. The head kidney functions as a primary haematopoietic organ, exhibiting distinct lymphoid and non‐lymphoid zones supported by a reticular framework. The trunk kidney serves an excretory role, and its tissue contains dispersed renal corpuscles. Ultrastructural analyses revealed typical cellular features, including well‐developed rough endoplasmic reticulum and melano‐macrophage‐associated lysosomes. Notably, structural abnormalities—including mitochondrial swelling, cristae fragmentation, and mild dilation of the rough endoplasmic reticulum—were observed in the head kidney; these may potentially reflect early immune activation or sublethal environmental stress. These baseline findings would provide critical morphological references and lay a foundation for future studies on immune function, disease pathology, and conservation strategies in H. bleekeri .

Development of a Phage‐Display Derived Peptide‐Based Colloidal Gold Strip for Rapid Detection of Enterocytozoon hepatopenaei via Spore Wall Protein Interaction - Jia‐rong Xie; Hao Li; Ben Chen; Yan‐chang Fan; Yu‐hao Gong; Liqun Lu (Journal of Fish Diseases, 2025)
Infection by Enterocytozoon hepatopenaei (EHP) leads to stunted or arrested growth in shrimp, causing significant economic losses in shrimp aquaculture. In this study, the spore wall protein EhSW12 was expressed using a prokaryotic expression system. Subsequently, phage display technology was employed to screen for peptides that interact with EhSW12. A rapid detection method was developed that bypasses the laborious procedure of extracting tissue DNA samples. Instead, enzymatic digestion was used to lyse the spore wall protein present in tissue homogenates, thereby enabling direct detection of EhSW12 via antigen colloidal gold rapid test strips and dot blot assays. The colloidal gold test strips, noted for their convenience and rapidity, satisfy the requirements for on‐site testing, while the dot blot method—with its simple operation—is well suited for high‐throughput sample analysis. Both methods were compared with the national standard qPCR assay. Specificity was validated using various shrimp antigens prepared in the laboratory; the results demonstrated that only the EHP antigen yielded a positive reaction, with no cross‐reaction observed with other common shrimp pathogens (e.g., white spot syndrome virus, decapod iridescent virus and highly pathogenic Vibrio ). Sensitivity tests indicated that the minimum detection limits for the test strip and dot blot methods were, respectively, 7 × 10 6 copies and 5.2 × 10 4 copies. In summary, both methods exhibit strong specificity, high sensitivity, rapid detection speed and operational simplicity—characteristics that make them highly suitable for large‐scale on‐site rapid testing.

Population Genomics and Climate Change Vulnerability in Two Sympatric Desert Rodents - Tian Tian; Jilong Cheng; Yu Zhang; Lin Xia; Yilin Chen; Fangyuan Yang; Zhixin Wen; Yaqian Cui; Weibo Wang; Xueying Zhang; Yanhua Qu; Qisen Yang (Global Change Biology, 2025)
Climate change poses a severe threat to desert ecosystems; however, understanding how specialized desert species respond to changing climate remains limited. These species are confronting extreme changes, including intensified droughts, altered precipitation, and temperature patterns. Here, we integrate population and ecogenomic approaches to examine population genetic structure, demographic history, and climate adaptation in two distantly related, sympatric rodent species in arid and semi‐arid regions in East Asia. We further combine genomic offset analysis, ecological niche modeling, and landscape connectivity assessments to evaluate their climate change risks. Our results reveal that the two species have diverged into five geographically distinct lineages, each associated with a different arid region. Lineage divergence times are estimated between 20 and 400 thousand years ago, with population size declines occurring around the Last Glacial Maximum. While the two species exhibited distinct climate adaptation, evidenced by different key climatic variables and associated genes identified for each species, they exhibited congruent vulnerability to future climate change. This was indicated by parallel patterns of genomic offset and niche suitability loss. Under future climate change scenarios, eastern lineages in high precipitation seasonality areas (e.g., DB lineages in Horqin Sandy Land) face a higher risk due to substantial genomic offset, habitat loss, and reduced connectivity. In contrast, lineages on the west ranges with low precipitation seasonality (e.g., QH lineages in the Qaidam Basin and HL lineage in the Changtang Plateau) appear less vulnerable, characterized by lower genomic offset and the expansion of desert habitats. Overall, this study provides a comprehensive framework for identifying vulnerable populations and predicting responses to climate changes in desert species, offering critical insights for the conservation of desert ecosystems.

High Quality, Granular, Timely, Trustworthy and Efficient Vertebrate Species Distribution Data Across a 30,000 km 2 Protected Area Complex - Yinqiu Ji; Alex Diana; Xueyou Li; Eleni Matechou; Jim E. Griffin; Shuwei Liu; Mingjie Luo; Chunying Wu; Ru Bai; Chenyang Yao; Tingting Yin; Feng Dong; et al. (Ecology Letters, 2025)
The routine generation of species distribution data at scale remains a challenge. We used aquatic environmental DNA metabarcoding to sample vertebrate species across the 30,000 km 2 Gaoligongshan region along the China–Myanmar border. In just 56 calendar days (33 researcher‐field‐days + 69 researcher‐lab‐days), we detected 389 vertebrate species, of which 35 are Red‐Listed. We introduce the ‘eDNA‐aware’ OccPlus occupancy model, which accounts for false‐negative and false‐positive error in the field and lab. OccPlus leverages the taxonomic breadth of eDNA datasets by using ordination to estimate species occupancies. We recover known biogeographic patterns and find that native terrestrial and fish species have higher occupancies inside protected areas while domesticated species and non‐native fishes have higher occupancies outside them. Our study demonstrates how eDNA metabarcoding can obtain high‐quality, granular, timely, trustworthy and efficient species distribution data to facilitate nature conservation and restoration.

Molecular Functional Diversity of Foliar Endophytic Fungi and Their Contributions to Seedling Survival in a Subtropical Forest - Baocai Han; Yunquan Wang; Sirong Zhang; Xiangcheng Mi; Lei Chen; Xiaojuan Liu; Keping Ma; Yu Liang (Ecology Letters, 2025)
Plant‐microbe interactions are critical in shaping forest dynamics, yet the molecular functions through which foliar endophytic fungi (FEF) influence seedling survival and coexistence remain unresolved. By combining FEF transcriptomics with seedling dynamics in a subtropical forest, we tested whether FEF molecular functions regulate seedling survival via host fitness differences and niche differentiation under modern coexistence theory. We found that FEF transcript diversity was strongly associated with host divergence time and maximum height, and FEF functions significantly enhanced seedling survival through fitness‐related and niche‐related processes. Among these FEF functions, gene ontology (GO) terms with high host‐phylogeny dependence enhance seedling survival through fitness differences associated with multi‐organism interactions, while those with high host‐trait dependence enhance seedling survival through niche differentiation related to basic life processes. Our findings establish a bridge between microbial functional genomics and modern coexistence theory in natural forests.

Probabilistic Simulations and Projections of Global Temperature Based on Greenhouse Gases - Hang Yu; Long Wang; Yuanfang Chen (International Journal of Climatology, 2025)
Climate simulations and projections play a critical role in the research of climate change. Their estimated values and ranges are often calculated by the multi‐model ensemble. Therefore, in order to enrich research methods and reduce uncertainty, this paper simulates and projects global temperature anomalies based on a non‐stationary probability model, using greenhouse gases as covariates and calculates the time profile of the exceedance probabilities for each temperature under various emission scenarios. The results show that the simulated interval includes the majority of the actual temperatures, and the projected future temperatures are close to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change. The very likely (likely) ranges of uncertainty are 0.38°C (0.20°C), which reduce the uncertainty. The probability of global temperature anomalies exceeding 3°C is very small, and the 1.5°C global warming level is unlikely (very low scenario), about as likely as not (low scenarios) and very likely (intermediate scenarios) to be exceeded. Furthermore, the time profiles can accurately represent the probability of exceeding a certain temperature for each year.

Distinct cellular localization of α- synuclein and β-synuclein in the chick retina - Fang He; Lin Liu; Shaoxuan Wang; Xin Lin; Guiyu Guan; Xiaoqian Lai; Xi Yu; Xiaotian Wu; Zhihao Shen; Bilin Rao; Mei-Ling Gao; Xuejiao Chen; et al. (Brain Structure and Function, 2025)

Plumbagin disrupts the mature biofilm of Staphylococcus aureus - Hui Yuan; Ming Lu; Chen Shi; Chunshuang Li; Ze Yao; Hui Shang; Xiang Li; Heshui Yu; Songtao Bie (Biofouling, 2025)

Decoupling and decomposition analysis of industrial carbon emissions, and projection of its future trends: A case study of Quanzhou, China - Yanxi Tang; Jing Xu; Muping Shen; Jiachang Zuo; Fengyi Yu; Yingmao Tang; Tingting Liu; Hongjun Jin; Yongjin Luo; Qingrong Qian; Qinghua Chen (Environment, Development and Sustainability, 2025)

Associations between Plasma Metal Concentrations and Mortality Risk in Non-Small-Cell Lung Cancer Patients: A Prospective Cohort Study - Yan Liu; Xiao-Yun Chen; Jing-si Chen; Miao Xu; Hong-Jun Zhang; Quan Tang; Yu‑Song Zhang; Da‑Peng Li; Li-Qiang Qin; Kun Wang (Biological Trace Element Research, 2025)

Two new amplisins with antibacterial activities from Akanthomyces attenuatus - Fan Cai; Wen Xie; Haoyu Yu; Xingtong Chen; Wei Lin; Jianbin Xiao; Chao Chen; Mingliang Zhang; Qin Li; Huaidong Zhang; Hui Zhang; Li Li (Natural Product Research, 2025)

Collision Avoidance Pattern with Collective Wisdom: Ship Action Decision-Making Azimuth Map Construction Based on COLREGs - Ziwei Wang; Fei Shao; Chong Zhang; Hongchu Yu; Shuzhe Chen; Lei Wu (Journal of Marine Science and Engineering, 2025)
Ship collision avoidance decision-making is a core determinant of navigational safety, and its effectiveness directly governs a ship’s ability to operate safely in a complex environment. Although successive editions of the COLREGs have provided a relatively systematic qualitative description of the principal encounter state and corresponding handling principles, they still lack a quantitative specification of collision avoidance actions. As a result, ship officers must rely heavily on experiential judgment for state recognition and decision-making in real operations, which in turn increases the likelihood of human error-induced failures in avoidance. To address this problem, this study constructs a COLREG-compliant collision avoidance decision azimuth map derived from the collective wisdom of ship officers. Specifically, a two-stage mining process tailored to large-scale AIS data is designed: in the first stage, ship–ship encounter cases are extracted from the full dataset, and, in the second stage, collision avoidance actions are mined from these encounter cases. Subsequently, a decision tree classification model is employed to partition the latent relationships between the relative motion features of two ships and their collision avoidance actions under different encounter scenarios, thereby constructing a data-driven ship collision avoidance decision azimuth map. Finally, taking the eastern coastal waters of China as a case study, the constructed ship collision avoidance action azimuth map is shown to provide scenario-specific guidance for two-ship encounters, offer an objective basis for the quantitative enrichment of COLREGs, and supply a methodological reference for future autonomous ship collision avoidance systems.

CENPI Promotes the Progression in Oral Squamous Cell Carcinoma and Is Regulated by E2F4 - Yi Chen; Fei Duan; Xinxing Duan; Xutao Wen; Xiong Yu; Dan Li (Cell Biochemistry and Biophysics, 2025)

Seasonal dynamics and vertical distribution of ecosystem-level carbon stocks in different vegetation types of the Minjiang estuary wetland - Yulong Chen; Maxiao Zhang; Jialong Guo; Qi Liu; Yu Zhang; Zhihao Li; Addo-Danso D. Shalom; Shubin Li; Lili Zhou (Frontiers in Marine Science, 2025)
Coastal wetlands play a crucial role in the global carbon cycle and climate regulation by serving as significant reservoirs of ecosystem carbon stock. However, their carbon sequestration capacity is strongly influenced by vegetation types, as well as the seasonal dynamics and vertical distribution of soil organic carbon. In this study, four wetland ecosystem types in the Minjiang Estuary— Kandelia candel , Phragmites australis , Cyperus malaccensis , and the unvegetated Tidal flat (control)—were investigated to assess the characteristics of ecosystem carbon stocks. The results showed that total ecosystem carbon stock was highest in K. candel —dominated vegetation (161.00 t C ha -1 ), followed by C. malaccensis (155.29 t C ha -1 ), and P. australis (128.44 t C ha -1 ), while the Tidal flat exhibited the lowest carbon value (49.08 t C ha -1 ). Vegetated wetlands stored 2.6-3.3 times more carbon than unvegetated Tidal flats, underscoring vegetation’s key role in carbon accumulation. Across all sites, soils contained the vast majority (92.23%-95.05%) of ecosystem carbon, while vegetation accounted for only (4.94%-7.77%). Distinct seasonal patterns were observed that carbon stock in the K. candel ecosystem showed spring maxima and autumn minima, whereas the herbaceous wetlands ( P. australis and C. malaccensis ) peaked in autumn. In contrast, carbon stock in the Tidal flat peaked significantly during summer. Vertical distributions of soil organic carbon (SOC) stock exhibited distinct site-specific patterns. The K. candel wetlands exhibited SOC stock peak in the 20–40 cm soil layer across seasons, while the P. australis and C. malaccensis wetlands generally decreased SOC with depth increasing except for in autumn. In the Tidal flat, SOC stock increased with soil depth in spring and autumn but peaked at 20–40 cm in summer and winter. Correlations analysis indicated that soil moisture and temperature significantly promoted carbon accumulation, whereas high bulk density and low pH constrained carbon storage, particularly in K. candel and P. australis wetlands. These findings provide critical insights into the carbon stock dynamics and seasonal variability of different coastal vegetation types, offering a scientific basis for the conservation of coastal wetland ecosystems and the development of carbon enhancement strategies in China.

Key roles of milk-derived extracellular vesicles in intestinal tract, with special emphasis on microRNAs in extracellular vesicles - Xue Bai; Jingwen Shang; Hong Yu; Chunshuang Wu; Xinping Chen; Xiqing Yue; Mei Yang (Critical Reviews in Food Science and Nutrition, 2025)

Prediction of the potentially suitable areas of Osmanthus cooperi in China under climate change using MaxEnt modeling - Jiaqi Zhou; Yilin Li; Zhirun Yu; Lin Chen (Environmental Monitoring and Assessment, 2025)

Investigating the influence of MSPA - driven spatial arrangement in UGI on carbon sink efficiency - Hangna Dong; Yu Chen; Bo Tang; Ren Lv; Jian Jin (Environment, Development and Sustainability, 2025)

Sex- and Age-Specific Inverted U-Shaped Links between Dietary Iron Intake and Serum α‑Klotho in Chinese Adults - Baodi Xing; Jie Yu; Yiwen Liu; Qi Gao; Xinyue Chen; Shuli He; Fan Ping; Lingling Xu; Wei Li; Huabing Zhang; Yuxiu Li (Biological Trace Element Research, 2025)

The right to environment at sea: a human rights-based approach to marine environmental protection - Guanding Wang; Liang Yu; Xi Chen (Frontiers in Marine Science, 2025)
The marine environment is becoming increasingly fragile and complex, posing serious threats to fundamental human rights. Despite the growing interconnection between marine protection and human rights, a significant gap persists between the international law of the sea and human rights law. The former remains state-centered and largely overlooks human rights, while the latter has developed primarily in land-based contexts and offers limited tools for protecting the marine environment. This article advances a human rights–based approach by introducing the concept of “the right to environment at sea” and illustrating its normative content. It identifies the right-holders, duty-bearers, and corresponding obligations, and demonstrates the unique advantages of this framework in addressing deep-sea mining, marine pollution, and biodiversity protection. It further explores potential pathways to activate the proposed right, including systemic treaty interpretation under Article 31(3)(c) of the Vienna Convention and procedural mechanisms through human rights treaty bodies, the Human Rights Council, regional human rights courts, the International Tribunal for the Law of the Sea, and the International Court of Justice. It argues that this rights paradigm adds values to marine environmental governance by strengthening State obligations and accountability.

Using an acidic vesicle tracer to identify potential bacterivores in coastal waters of the subtropical Western Pacific Ocean - Yun-Chi Lin; Yu-Chen Lin; Kuo-Ping Chiang; Chien-Pang Chin; Wen-Chen Chou (Frontiers in Marine Science, 2025)
Bacterivores play a key role in transferring energy through microbial food webs and are broadly classified as heterotrophic or mixotrophic based on the presence of inherent chloroplasts. Mixotrophs, especially in low-latitude regions, have recently gained attention due to their dual roles as primary producers and bacterial grazers, which enable them to thrive in nutrient-poor, stratified waters where traditional autotrophs or heterotrophs may be less competitive. This study investigated the composition of bacterivores in the coastal waters of northeastern Taiwan during the warm season (July and August 2022). A combination of LysoTracker staining, flow cytometry sorting, and 18S rRNA gene amplicon sequencing was used to rapidly identify heterotrophic and mixotrophic nanoflagellates (HNFs and MNFs, respectively) based on chloroplast autofluorescence. The dominant eukaryotic lineages included Alveolata, Stramenopiles, Opisthokonta, Chlorophyta, and Rhizaria. HNFs were primarily composed of MAST clades, choanoflagellates (Opisthokonta), Telonemia, and Radiolaria, while MNFs included cryptophytes, haptophytes, and chlorophytes such as Mamiella , Mantoniella and Tetraselmis , as well as stramenopiles like Dictyochophyceae and Chrysophyceae. Notably, several non-motile chlorophytes, including Chloropicon and members of Pycnococcaceae, were identified as potential bacterivores based on Lysotracker signals; however, their phagotrophic capability requires further confirmation in future studies. Despite the limitations of LysoTracker-based methods, this study reveals previously overlooked mixotrophic diversity and highlights the need for further validation. These findings advance our understanding of carbon flow and microbial dynamics in subtropical marine ecosystems under changing environmental conditions.

Full waveform inversion of cross-hole GPR data using Markov Chain Monte Carlo method based on SE-Resnet - Sheng-chao Wang; Yu-fei Wang; Yi-fei Liu; De-fu Zhang; Hui Sun; Gong-min Chen; Xiang-yu Tan (Applied Geophysics, 2025)

Identification of Ocean Thermal Energy Conversion Heat Exchange Model Based on Long Short-Term Memory Network and Heat Exchange Efficiency Improvement Study - Yanjun Liu; Xiu You; Mingqian Tian; Tianxu Zhang; Yun Chen; Yanni Yu (Journal of Marine Science and Engineering, 2025)
The core of ocean thermal energy conversion (OTEC) is the transfer and conversion of heat energy, and the heat exchanger is a key component of the heat transfer between the surface warm seawater and the lower cold seawater. The working fluid has a significant impact on the efficiency of the entire cycle in the temperature difference cycle. This study aimed to improve heat exchange efficiency. The article studied heat exchangers, used R134a as the circulating medium, and applied ANSYS-FLUENT 2020R2 simulation software to analyze the variation in heat transfer coefficients. We obtained the trend in the heat transfer coefficient of the heat exchanger with the shape of an elliptical tube under the condition of ocean temperature difference cycles. Then we used a long short-term memory network and Adam optimization algorithm to establish the prediction model. The NSGA-II 11 algorithm was used to realize optimization objectives of the highest heat transfer efficiency and the smallest cross-sectional area of heat transfer tubes along the X and Y directions. Finally, the parameters of the evaporator and condenser ultimately resulted in three optimal solutions. The results of this study can provide a certain theoretical basis and reference value for the efficiency analysis, structure optimization, and experimental research of the subsequent ocean differential circulation heat transfer.

Comprehensive Index System for Evaluation of Ecological Seawalls - Peng Yuan; Yu Han; Sihao Chen; Jian Zeng; Xiaoran Wei; Yongping Chen; Jiali Gu (Journal of Marine Science and Engineering, 2025)
Seawalls are important infrastructure for coastal areas to resist natural disasters such as storm tides and typhoon waves. Traditional seawall construction often causes intertidal zone fragmentation and coastline hardening, which affects the ecological function of the coastline. Ecological seawalls have both functions of disaster prevention and ecology and have become an inevitable trend in seawall construction at home and abroad. However, constructing a comprehensive, scientifically rational evaluation index system for ecological seawalls is a critical and pressing challenge. This study is based on the summary of practical research on seawall construction and puts forward the connotation of ecological seawall clearly. Twenty indexes that reflect the safety, ecology and sustainability of ecological seawalls were selected, and a three-level comprehensive evaluation index system of ecological seawalls was constructed using the Analytic Hierarchy Process (AHP). Three cases, including the second stage of the ecological seawall of the large-scale narrowing project in Yuyao City, Zhejiang Province, were used in this evaluation system. The application results showed that the constructed comprehensive evaluation index system of ecological seawalls in this study has a reasonable evaluation index, and the evaluation result is reliable, which is suitable for popularization and application. This study clarifies the index system and construction method for the comprehensive evaluation of ecological seawalls, puts forward typical measures for ecological seawall construction from five aspects: shore beach protection, seawall body structure, seawall surface protection, building materials and vegetation selection, and provides theoretical and practical guidance for studying and judging the ecological problems of seawalls and guiding the construction of ecological seawalls.

The connection between skeletal muscle and spinal canal membrane of Takifugu rubripes and its anatomical and physiological significance - Yang Song; Wen-Bin Jiang; Yu-Yu Xiong; Chun-Zhuo Shi; Hua-Xun Lai; Jing-Xian Sun; Lin-Lin Chen; Bo Liu; Yan-Yan Chi; Ji-Hang Li; Yi-Tong Sun; Xu-Hui Zhang; et al. (Frontiers in Marine Science, 2025)
Introduction The myodural bridge (MDB) is considered one of the circulatory dynamics of cerebrospinal fluid (CSF). Initially identified in the human neck, it has since been documented across diverse vertebrates, including fish with analogous “MDB-like” structures. The teleost Takifugu rubripes , which exhibits a high degree of genetic homology with humans, serves as an excellent model for such comparative studies. Investigating its MDB-like structure can therefore provide a morphological basis for elucidating the mechanism of CSF circulation and its evolution during the vertebrate land–water transition. Methods In this study, the morphology, development, and ultrastructure of MDB-like structure of Takifugu rubripes were explored. Three fresh adult T. rubripes were selected for gross anatomy. After incubation, 33 T. rubripes aged 13–120 days after hatching (dah) were fixed in 10% formalin solution. The samples aged 50–120 dah were further decalcified with EDTA for histological paraffin sectioning and Masson staining. Four cases aged 106 dah were fixed with 2.5% glutaraldehyde, two of which were observed by scanning electron microscopy, and two cases were observed by transmission electron microscopy. Results Through light microscopy and electron microscopy, the results of the current study is that there are three types of fiber connections (MDB-like) between skeletal muscle and the spinal canal membrane in T. rubripes : (1) The fibers from the myocomma attach to the spinal canal membrane; (2) The epimysium connects to the spinal canal membrane directly or connects to the spinal canal membrane through reticular, filamentous fibers, or fibers emitting from the perimysium; and (3) The fibers from the end of the muscle bundle stop at the spinal canal membrane. These connections mainly exist on the sides of each vertebral interspace and may function similarly to the MDB. Discussion Developmentally, “MDB-like” structures appeared in T. rubripes hatched at 18 dah, began to transmit force at 21 dah, and may have a positive correlation in development with the muscle and spinal canal membrane. This experiment provides developmental morphological information for comparative studies on the conservation and interspecies differences of MDB in evolution and provides informational support to explore the physiological function of MDB in humans.

Associations between biological age acceleration and hospitalization burden of community-acquired pneumonia: a cohort study - Biying Wang; Chen Qian; Liping Yi; Youyi Zhang; Hongjie Yu; Xiaohua Liu; Yonggen Jiang; Tao Zhang; Genming Zhao (GeroScience, 2025)

Neuroprotective Effects of Glucosamine in Huntington’s Disease Through NLRP3 Inflammasome Inhibition - Lichieh Julie Chu; Yi-ting Hsu; Yu Aoh; Chih-Yuan Cheng; Hui-Hsuan Wang; Ming-Tse Wu; Hao-Hsuan Li; Xiu-Yuan Lai; Kuo-Feng Hua; Chiung-Mei Chen; Tz-Chuen Ju (Journal of Neuroimmune Pharmacology, 2025)

Peroxymonosulfate activation by iron-sulfur tailings doped with SiO2 for efficient degradation of tetracycline - Chen-Chen Yin; Chun Cheng; Peng-Yu Zhang; Zheng-Yuan Zhang; Ying Qin; Li-Pin Xue; Yu-Qi Feng; Bai Sun; Shu-guang Zhu (Environmental Science and Pollution Research, 2025)

Influence of Human Activity on Wet Deposition and Nitrogen Species in Coastal and Marine Environments - Hung-Yu Chen; Jia-Han Lin; FuJung Tsai (Journal of Marine Science and Engineering, 2025)
In this study, 101 and 102 rainwater samples were collected from April 2020 to February 2024 in a coastal and marine area, respectively. The results show that the Cl/Na ratios in both study areas were lower than the seawater value (1.17), suggesting chloride depletion. The chloride depletion rates in both areas decreased after the COVID-19 lockdown period. The molar ratio of NH4+ to non-sea-salt sulfate (nss-SO42−) was 1.54, with a mixture of (NH4)2SO4 and NH4HSO4 in the coastal area, and 0.83, with NH4HSO4 as the main form, in the marine area. A decreasing trend attributed to high O3 and relative humidity (RH) levels occurred in 2022. Among the dissolved organic nitrogen (DON) species, DON accounted for 24% and 32% of the total dissolved nitrogen (TDN) in the coastal and marine areas, respectively, indicating a greater relative contribution under lower anthropogenic influence. On the basis of the correlation between the species and source analysis results, NO3− mainly originated from fossil fuel combustion, NH4+ originated from agricultural emissions and secondary aerosols, and DON originated from secondary aerosols via combustion processes and natural emissions. In terms of the flux, due to lockdown activities, the Dissolved Inorganic Nitrogen (DIN) flux decreased significantly from 40.6 to 19.3 mmol m−2 yr−1 in the coastal area and from 27.7 to 15.1 mmol m−2 yr−1 in the marine area. Additionally, a slight decrease occurred in the DON flux, from 21.6 to 19.3 mmol m−2 yr−1 and from 27.7 to 15.1 mmol m−2 yr−1, respectively. Regarding new production, based on nitrogen input, the level in the coastal area decreased from 5.83 to 2.10 g C m−2 yr−1, and that in the marine area decreased from 3.92 to 1.55 g C m−2 yr−1, indicating a significant reduction during the COVID-19 lockdown.

Influence Mechanism of Well Location and Near-Well Secondary Hydrates on Gas Production of Class 1S Hydrate Reservoirs - Xian Li; Chenlu Xu; Hongfeng Lu; Zihao Zhao; Jiawang Chen; Liwen Nan; Lu Yu; Jinwen Du; Changwen Xiao; Bo Liu; Zhejun Pan (Journal of Marine Science and Engineering, 2025)
In recent years, a new type of natural gas hydrate reservoir (designated as Class 1S reservoir) has been discovered in the Qiongdongnan Basin. Within this hydrate reservoir, free gas and hydrate coexist within the same stratum. The Class 1S reservoir is comprised of three distinct zones: the gas accumulation zone, the three-phase zone, and the hydrate-bearing zone. It exhibits significant commercial development potential. This paper analyzes the formation mechanism and geological context of Class 1S hydrates. A geological model was established and numerical simulation methods were employed to evaluate its production capacity, elucidating the evolutionary patterns of hydrate saturation distribution at different well locations. The simulation results indicate that production wells should be prioritised in gas accumulation zones in order to achieve the highest cumulative gas production. Additional production wells may be considered in later stages to enhance recovery rates. Secondary hydrate formation significantly impacts production in Hydrate-bearing zone and three-phase zone. Measures such as wellbore heating can be employed to minimize secondary hydrate formation around the wellbore.

Extraction optimization, structure characterization and In vitro antioxidant activity of polysaccharides from Chuju, a cultivar of Chrysanthemum morifolium Ramat - Kaiqi He; Na Chen; Wenjuan Pan; Shasha Yu; Shuangjie Zhu (Natural Product Research, 2025)

Investigating antidiabetic drug targets as potential therapeutic modulators for schizophrenia - Yu-Sheng Huang; Xu Lin; Ya-Juan Xu; Gui-Bing Chen (Psychopharmacology, 2025)
Rationale Certain types of antidiabetic drugs (ADs) have been proven to improve cognitive functions and symptom dimensions in schizophrenia (SCZ). Objectives Schizophrenia is a major contributor to social functional impairment, and antipsychotics (APs) remain the cornerstone of its treatment. Investigating the potential of antidiabetic drugs as APs could significantly advance therapeutic strategies for schizophrenia. Methods To assess this potential, we employed an integrated analytical framework that included two-sample Mendelian randomization (MR) using genetic proxies for antidiabetic drug targets, multivariable MR (MVMR), and colocalization analyses. Furthermore, gene and drug enrichment analyses alongside molecular docking studies were performed to elucidate underlying mechanisms and identify candidate drugs. The analysis utilized summary statistics from genome-wide association meta-analyses (GWAS) of schizophrenia, as well as gene expression data from the eQTLGen consortium. Results A total of fourteen drug targets were identified among eight major antidiabetic drugs. Notably, RXRB, a target of thiazolidinediones (TZDs), exhibited a strong inverse association with schizophrenia risk (OR: 0.28, 95% CI: 0.21–0.38, P < 0.001). Other significant targets included GPD1 (targeted by metformin), LRP2 (insulin), SLC5A2 (SGLT2 inhibitors), and ABCC8/KCNJ11 and INS (sulfonylureas). Primary and secondary MR analyses confirmed the associations of RXRB, INS, LRP2, and SLC5A2 with gene expression levels. Drug enrichment and molecular docking analyses identified bezafibrate as a promising candidate for repurposing as an AP. Conclusion Antidiabetic drugs may possess therapeutic potential in schizophrenia by modulating specific drug-related pathways.These findings provide new theoretical support for the selection of ADs in patients with schizophrenia comorbid with diabetes, and also offer new insights for the future development of APs.

Establishment of a Padlock Probe-Based Fluorescence Quantitative PCR Method for the Detection of the SARS-CoV-2 Omicron S371L Mutation - Yangqing Zhong; Luxin Yu; Yanzhen Lin; Wenjuan Xu; Lingwei Chen; Zhangquan Chen; Xiang Xiao (Journal of Fluorescence, 2025)

Nitrogen fertilization stimulated grassland nitrogen transformation by increasing substrate quantity and ammonia-oxidizing bacteria abundance - Yan-Yu Hu; Cai-Yan Lu; Zhi-Wei Zhang; Guo-Jiao Yang; Xin Chen; Xiao-Tao Lü (Plant and Soil, 2025)

Soil and enzymatic C:N:P stoichiometry response to carbon and nutrient input: evidence from long-term fertilization experiments - Qiong Xiao; Yaping Huang; Guoping Chen; Kailou Liu; Yu Jiang; Boku Zhou; Ping Zhu; Xiaori Han; Junyong Ma; Shutang Liu; Shaomin Huang; Aijun Zhang; et al. (Plant and Soil, 2025)

The lysosomal cysteine protease cathepsin L promotes stemness and multidrug resistance of non-small cell lung cancer by targeting HGF activator - Hui Shi; Jianyu Xu; Juan Wu; Sha Hu; Xi Chen; Qianfang Hu; Qian Liu; Yanxia Yu; Xinyuan Ding; Wenjuan Wang (Molecular and Cellular Biochemistry, 2025)

Research on Environmental Response Characteristic of Super-Long Inclined Shaft Tunnel and CO Diffusion and Ventilation Optimization of Blasting Procedures - Kong-fei Yu; Huai-bing Wang; Hong-yan Wang; Chen-qi Fan; Bu-rui Liu; Xuan-ke Ren (Applied Geophysics, 2025)

Chemical constituents and bioactivities of fermented rose (from Yunnan ) extract - Bo Peng; Yining Hao; Yueyue Chen; Shishuai Yu; Liping Qu (Natural Product Research, 2025)

Waveform purification of ultrasonic signals from xylem cavitation in tree species based on U-MFCC feature extraction and voiceprint recognition models - Siyu Chen; Jiayang Ding; Yifeng Li; Zongheng Xu; Shangshang Ling; Jing Yu; Xiangxue Zhang (Computers and Electronics in Agriculture, 2025)

Large-scale single tree information extraction of oil palm in Malaysia based on sub-meter visible light satellite images - Sen Zhang; Nan Li; Yaoping Cui; Jinwei Dong; Le Yu; Lishan Ran; Ziyue Chen; Jiqiang Niu; Wei Yan; Kasturi Devi Kanniah; Xiangming Xiao (Computers and Electronics in Agriculture, 2025)

Establishment of one-step reverse-transcription loop-mediated isothermal amplification (RT-LAMP) assay for the detection of potato aucuba mosaic virus - An Yan; Yunting Lei; Zhaoyao Yu; Gaoli Wu; Wenzhuo Feng; Xiangru Chen (Crop Protection, 2025)

Submarine groundwater discharge governs dissolved carbon cycling: Multi-scale evidence from a large river-dominated groundwater-saltmarsh-estuary system - Jianan Liu; Liying Lin; Xueqing Yu; Xiaogang Chen; Tong Peng; Xinyi Lin; Xunchi Zhu; Jinzhou Du (Marine Pollution Bulletin, 2025)

Social-ecological memories as references for biodiversity restoration and conservation action in coastal community - Chia-Hsuan Hsu; Yu-Wen Wu; Jiefeng Kang; Hung-Kai Chiu; Mei-Ching Li; Wei-Ting Chen (Marine Pollution Bulletin, 2025)

Source apportionment and ecological risk of heavy metals in sediments from estuaries and bays in China: insights into cross-regional transport - Haiyang Liu; Yiqing Chen; Haoqian Shi; Xudong Huang; Youngchul Kim; Wanli Hou; Jianghua Yu (Marine Pollution Bulletin, 2025)

Differential response patterns of bacterial communities in seawater and sediments to the Chaetomorpha valida bloom in sea cucumber Apostichopus japonicus aquaculture ponds - Hongxia Zhang; Kexin Xu; Ronglian Xing; Linqian Wang; Renyu Liu; Xin Wang; Lihong Chen; Rui Li; Zhen Yu; Xuebin Cao; Cao Cheng; Qun Su (Marine Pollution Bulletin, 2025)

Per- and polyfluoroalkyl substances in tissues of intermediate egrets (Ardea intermedia) from the South China Sea - Ling Mo; Jun Xiang; Ming-Yang Wang; Yu-Quan Zhang; Qin-Wei Hao; Qi-Fei Peng; Yong-Fu Chen; Yu-Feng Hu; Jing Zheng; Qiao Xing; Bin Tang; Li-Cheng Wang (Marine Pollution Bulletin, 2025)

Spatial-temporal shipping risk assessment along Asia-Europe route due to ocean waves - Rong Jing; Chen Chen; Shenping Hu; Kenji Sasa; Hongchu Yu; Yu Hu (Ocean & Coastal Management, 2025)

Study on multi phase flow characteristics and anti-clogging mechanism of liquid fertiliser distributors using CFD-DEM coupling method - Peijie Guo; Jiahui Yu; Peilin Zhong; Yuxiang Chen; Haiying Wang; Yu Chen; Jun Chen; Shuo Zhang; Aiping Xiao (Biosystems Engineering, 2025)

Molecular insights in outstanding performance of Ca2+ bridging MXene/Sodium alginate composite membranes - Hua Li; Hongjun Lin; Saleem Raza; Zhiyu Zhao; Siyuan Chen; Yue Wang; Qianqian Zeng; Cheng Chen; Wei Yu; Liguo Shen (Water Research, 2025)

Altitude regulates the response of nitrogen removal function to short-term flooding events in a riparian ecotone - Yu Gong; Xiaoling Li; Xiaodie Duan; Wenjun Shi; Siyue Li; Chen Ye; Quanfa Zhang (Water Research, 2025)

Microbial-mediated transformation shapes the molecular diversity of landfill leachate under anthropogenic and natural covariation - Qiurui Zhang; Jitao Lv; Shiyang Yu; Tianyu Chen; Yue Sun; Feifei Li; Lu Bai; Xianwei Wang; Xiaosong He; Yong Nie; Nanwen Zhu; Yawei Wang; et al. (Water Research, 2025)