Screening of microRNA and mRNA related to secondary hair follicle morphogenesis and development and functional analysis in cashmere goats - Fangzheng Shang; Yu Wang; Rong Ma; Youjun Rong; Min Wang; Zhihong Wu; Erhan Hai; Jianfeng Pan; Lili Liang; Zhiying Wang; Ruijun Wang; Rui Su; et al. (Functional & Integrative Genomics, 2022)
microRNA (miRNA) is a type of endogenous short-chain non-coding RNA with regulatory function found in eukaryotes, which is involved in the regulation of a variety of cellular and biological processes. However, the research on the development of cashmere goat secondary hair follicles is still relatively scarce. In this study, small RNA libraries and mRNA libraries of 45 days, 55 days, 65 days, and 75 days of fetal skin of cashmere goats were constructed, and the constructed libraries were sequenced using Illumina Hiseq4000, and the expression profiles of miRNA and mRNA in cashmere goat fetal skin were obtained. The differentially expressed miRNAs and mRNAs in six control groups were identified and the qRT-PCR experiment shows that the sequencing results are accurate. Sixty-six miRNAs related to secondary hair follicle development were screened, and used TargetScan and miRanda to predict 33 highly expressed miRNA target genes. At the same time, 664 mRNAs related to the development of secondary hair follicles were screened, and GO enrichment and KEGG pathway analysis were performed. It was found that some miRNA target genes were consistent with the screening results of mRNAs related to secondary hair follicle development and were enriched in Notch signaling pathway, TGF-β signaling pathway. Therefore, miR-145-5p-DLL4, miR-27b-3p-DLL4, miR-30e-5p-DLL4, miR-193b-3p-TGF-β1, miR-181b-5p-NOTCH2, and miR-103-3p-NOTCH2 regulatory network related to the development of secondary hair follicles were constructed and the results of dual-luciferase reporter gene assay indicated that there is a targeted relationship between chi-miR-30e-5p and DLL4, which will provide a basis for molecular mechanism of miRNA-mRNA in the development of the hair follicles in cashmere goats.

Metabacillus rhizolycopersici sp. nov., Isolated from the Rhizosphere Soil of Tomato Plants - Rong Ma; Shan-Wen He; Xing Wang; Kyu Kyu Thin; Ji-Gang Han; Xiao-Xia Zhang (Current Microbiology, 2022)

Prediction model for disc cutter wear during hard rock breaking based on plastic removal abrasiveness mechanism - Lei She; She-rong Zhang; Chao Wang; Zheng-qiao Wu; Lun-chuang Yu; Li-xin Wang (Bulletin of Engineering Geology and the Environment, 2022)

Mechanism of progressive failure of a slope with a steep joint under the action of freezing and thawing: model test - Cong Li; Rong-tang Zhang; Jie-bing Zhu; Bo Lu; Xiao-ke Shen; Xiao-wei Wang; Jie-sheng Liu; Liang-liang Wu; Xin-zhou Zhang (Journal of Mountain Science, 2022)

Fast forward modeling of muon transmission tomography based on model voxelization ray energy loss projection - Rong-Qing Zhang; Zhen-Zhu Xi; Wei Liu; He Wang; Zi-Yan Yang (Applied Geophysics, 2022)

Drivers of foliar 15 N trends in southern China over the last century - Songbo Tang; Jianfeng Liu; Frank S. Gilliam; Peter Hietz; Zhiheng Wang; Xiankai Lu; Feiyan Zeng; Dazhi Wen; Enqing Hou; Yuan Lai; Yunting Fang; Ying Tu; et al. (Global Change Biology, 2022)
Foliar stable nitrogen (N) isotopes (δ 15 N) generally reflect N availability to plants and have been used to infer about changes thereof. However, previous studies of temporal trends in foliar δ 15 N have ignored the influence of confounding factors, leading to uncertainties on its indication to N availability. In this study, we measured foliar δ 15 N of 1811 herbarium specimens from 12 plant species collected in southern China forests from 1920 to 2010. We explored how changes in atmospheric CO 2 , N deposition and global warming have affected foliar δ 15 N and N concentrations ([N]) and identified whether N availability decreased in southern China. Across all species, foliar δ 15 N significantly decreased by 0.82‰ over the study period. However, foliar [N] did not decrease significantly, implying N homeostasis in forest trees in the region. The spatiotemporal patterns of foliar δ 15 N were explained by mean annual temperature (MAT), atmospheric CO 2 (), atmospheric N deposition, and foliar [N]. The spatiotemporal trends of foliar [N] were explained by MAT, temperature seasonality, , and N deposition. N deposition within the rates from 5.3 to 12.6 kg N ha −1 year −1 substantially contributed to the temporal decline in foliar δ 15 N. The decline in foliar δ 15 N was not accompanied by changes in foliar [N] and therefore does not necessarily reflect a decline in N availability. This is important to understand changes in N availability, which is essential to validate and parameterize biogeochemical cycles of N.

Optimization of the Hydrodynamic Performance of a Double-Vane Otter Board Based on Orthogonal Experiments - Lei Wang; Xun Zhang; Rong Wan; Qingchang Xu; Guangrui Qi (Journal of Marine Science and Engineering, 2022)
An orthogonal experiment was conducted to study the effects of the aspect ratio, camber of the fore wing, and gap ratio of front and rear wing panels on the hydrodynamic performance of double-vane otter boards. The design of the orthogonal experiment comprised three factors (each having three levels), namely the aspect ratio (1.0, 1.5, and 2.0), camber (0.12, 0.14, and 0.16), and gap ratio (0.25, 0.30, and 0.35), the drag coefficient Cx and the lift coefficient Cy of nine otter board models obtained in a wind tunnel experiment, and the lift–drag ratio K obtained by calculation. The lift–drag ratio for a working angle of attack of 30° was selected as the inspection index, and the experimental data were analyzed in an orthogonal design-direct analysis. Analysis of each factor revealed that the optimal level combination of factors was A3B3C3 and that the decreasing order of the effects of the factors was A (aspect ratio) > B (gap ratio) > C (camber). The orthogonal experiment thus obtained an optimal otter board in terms of the aspect ratio (2.0), fore wing camber (0.16), and gap ratio (0.35), with the aspect ratio having the greatest effect on performance. The hydrodynamic performances of the otter board with the optimized structure and another otter board model were compared in numerical simulation, which verified the correctness of the analysis results. The experimental results provide a reference for the optimal design of the double-vane otter board.

Physiology, metabolism, antibiotic resistance, and genetic diversity of Harveyi clade bacteria isolated from coastal mariculture system in China in the last two decades - Hao Kang; Yongxiang Yu; Meijie Liao; Yingeng Wang; Guanpin Yang; Zheng Zhang; Bin Li; Xiaojun Rong; Chunyuan Wang (Frontiers in Marine Science, 2022)
Vibrio bacteria, particularly members of the Harveyi clade, are the most important pathogens of aquatic organisms that cause significant economic losses in the world. It is difficult to provide specific data on taxa of the Harveyi clade for biological research and prevention strategies. Therefore, we conducted an extensive phenotypic and antibiotic resistance study, as well as phylogenetic and molecular typing of 192 isolates of the Harveyi clade collection from 2000 to 2020 with a typical interannual difference from a coastal area in China. The isolates had a significant interspecific genetic and antibiotic resistance diversity. Based on the multilocus sequence analysis (MLSA) of housekeeping genes ( gyrB , pyrH , recA , and atpA ), 192 Harveyi clade isolates were rapidly and accurately classified into 10 species. The population of these isolates was composed of 95 sequence types (STs), of which 92 STs were newly identified, indicating a high degree of genetic diversity. ST327 ranked first, accounting for 11.5% of the total number of isolates (22 out of 192), followed by ST215 with 6.25%, while 63 STs included single isolates. At the metabolic level, the physiological and biochemical experiments revealed that all the Harveyi clade isolates were positive for oxidase and negative for melibiose. The isolates showed a varied tolerance to 11 antibiotics. No isolates were resistant to neomycin. The percentages of sulfadimidine-resistant strains (61 out of 192), sulfadiazine (44 out of 192), sulfamonomethoxine (44 out of 192), sulfamethoxazole (33 out of 192), thiamphenicol (34 out of 192), ciprofloxacin (52 out of 192), and enrofloxacin (31 out of 192) were 31.77%, 22.92%, 22.92%, 17.19%, 17.71%, 27.08%, and 16.15%, respectively. A proportion of 61.8% of the isolates presented a multiple antibiotic resistance index (MARI) lower than 0.1, indicating that the risk of antibiotic resistance transmission of most of the Harveyi clade is low in mariculture systems in China. These results provide substantial data to support further studies on the identification and genetic and metabolic diversity of Harveyi clade isolates in mariculture systems in China.

Antimicrobial Resistance and Genotype Characteristics of Vibrio scophthalmi Isolated from Diseased Mariculture Fish Intestines With Typical Inter-Annual Variability - Yongxiang Yu; Xiao Liu; Yingeng Wang; Meijie Liao; Miaomiao Tang; Xiaojun Rong; Chunyuan Wang; Bin Li; Zheng Zhang (Frontiers in Marine Science, 2022)
As an intestinal organism settled long-term within the gut of marine fish, Vibrio scophthalmi is a potential object for the bacterium genetic variation and adaptation research. The genetic diversity, antimicrobial resistance phenotype, and genotype of 33 V. scophthalmi isolated from diseased marine fish intestines between 2002 and 2020 were evaluated. The results showed that all isolates were frequently resistant to penicillins, cephalosporins, aminoglycosides, and macrolides and displayed multidrug-resistant (MDR) phenotype in vitro . Thirty percent of isolates were resistant to more than 20 different drugs. The average insensitive (resistant and intermediate) rate of V. scophthalmi isolates was 49.5%~81.8% between 2002 and 2020, but the t-test revealed that there was no significant difference in the drug-resistance rate of V. scophthalmi isolates with typical interannual variability. Eleven antimicrobial resistance genes ( strB , strA , ant(3 ˝)-I , mphA , blaPSE , qnrS , tetC , tetE , tetM , tetS , and int1 ) were detected in these isolates, but the antimicrobial resistance phenotypes and genotypes of these isolates were not consistent. Enterobacterial repetitive intergenic consensus polymerase chain reaction (ERIC-PCR) analysis indicated that 33 isolates could be divided into two clusters (G1 and G3) and two single isolates (G2 and G4), and the G2 cluster was isolated from South Sea C. undulates with typical geographical species differences. There was no significant correlation between the drug susceptibility and the genetic types of V. scophthalmi isolates. The results reveal the mismatch phenomenon between antimicrobial resistance and genotype of inherent V. scophthalmi in the marine fish intestines, and the antimicrobial susceptibility isolates might be a potential risk source for storage and transmission of resistance genes.

Factors Influencing Alzheimer’s Disease Risk: Whether and How They are Related to the APOE Genotype - Rong Zhang; Xiaojiao Xu; Hang Yu; Xiaolan Xu; Manli Wang; Weidong Le (Neuroscience Bulletin, 2022)
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease featuring progressive cognitive impairment. Although the etiology of late-onset AD remains unclear, the close association of AD with apolipoprotein E (APOE), a gene that mainly regulates lipid metabolism, has been firmly established and may shed light on the exploration of AD pathogenesis and therapy. However, various confounding factors interfere with the APOE -related AD risk, raising questions about our comprehension of the clinical findings concerning APOE . In this review, we summarize the most debated factors interacting with the APOE genotype and AD pathogenesis, depict the extent to which these factors relate to APOE -dependent AD risk, and discuss the possible underlying mechanisms.

Impact of heat stress on milk yield, antioxidative levels, and serum metabolites in primiparous and multiparous Holstein cows - Xue Chen; Jia Nan Dong; Ji Ye Rong; Jun Xiao; Wei Zhao; Natnael D. Aschalew; Xue Feng Zhang; Tao Wang; Gui Xin Qin; Zhe Sun; Yu Guo Zhen (Tropical Animal Health and Production, 2022)

An improved hybrid bream derived from a hybrid lineage of Megalobrama amblycephala (♀)×Culter alburnus (♂) - Dingbin Gong; Min Tao; Lihui Xu; Fangzhou Hu; Zehong Wei; Shi Wang; Yude Wang; Qingfeng Liu; Chang Wu; Kaikun Luo; Chenchen Tang; Rong Zhou; et al. (Science China Life Sciences, 2022)

Prediction of the sea buckthorn AQP gene structure and its spatiotemporal expression pattern under drought stress - Dan Zhang; Nanxiang Yang; Jiawei Dong; Cheng Wang; Qiangfeng Li; Rong Wang; Zhipeng Feng; Dejuan Xie; Guisheng Ye; Yuhua Ma (Journal of Plant Biochemistry and Biotechnology, 2022)

Dynamic Cause of the Sudden Death Event of Small Yellow Croaker (Larimichthys polyactis) in the East China Sea in Winter 2017 - Zilu Wei; Xiaohui Jiao; Jicai Zhang; Yunfei Du; Zengrui Rong; Hui Wu; Ya Ping Wang (Frontiers in Marine Science, 2022)
Small yellow croaker ( Larimichthys polyactis ), a benthic fish species widely distributed in the Northwest Pacific Ocean, plays an important role in the fishery catch of coastal countries. A large amount of dead small yellow croaker floated on the sea surface near 30.2°N, 125.3°E in the East China Sea on 19 February 2017, and more than 9,000 kilograms were caught by fishermen, which had never been recorded before. This study aims to investigate the dynamic causes of this sudden death event based on available in-situ, satellite and modelling data. The event occurred near the overwintering ground of small yellow croaker, where a majority of these fish assembled in winter. There were persistent ocean fronts at target site with average intensity of 0.05°C/km at sea surface and bottom in February 2017, which was the strongest in the past 5 years from 2015 to 2019. The fronts provided nutrients and food to fish, and the intense gradients prevented fish from crossing, thus forming “water barriers” to restrict the horizontal movement of fish. Due to enhanced convection, the water was well-mixed, enabling the demersal croaker to float to sea surface. The sea temperature was particularly warm in winter 2017, but then experienced a significant drop by more than 4.5°C in 40 days according to satellite and modelling datasets due to the northerly wind and the southeastward movement of cold eddy. The drop of temperature led to ‘cold shock’ of fish, affecting their physiological regulation and survival. Under the combined influence of these factors, a large number of small yellow croaker died and aggregated near the target site. This paper has a great reference value for further study on the living habits of small yellow croaker and their responses to marine dynamic changes.

Phytoplankton Distributions in the Kuroshio-Oyashio Region of the Northwest Pacific Ocean: Implications for Marine Ecology and Carbon Cycle - Yaoyao Wang; Rong Bi; Jing Zhang; Jiawei Gao; Shigenobu Takeda; Yoshiko Kondo; Fajin Chen; Gui’e Jin; Julian P. Sachs; Meixun Zhao (Frontiers in Marine Science, 2022)
The Northwest Pacific Ocean (NWPO) is a significant sink for atmospheric CO 2 but a paucity of large-scale phytoplankton surveys in the upper and lower euphotic zone results in uncertainties in estimates of the efficiency of the biological carbon pump there. Here, we report the spatial distribution of lipid biomarkers from diatoms (brassicasterol/epi-brassicasterol), dinoflagellates (dinosterol), and haptophytes (C 37 alkenones) as proxies of phytoplankton biomass and community structure in suspended particles from the surface and deep chlorophyll maximum (DCM) layers across low- and mid-latitude regions of the NWPO. Our observations suggest that these lipid biomarkers can be used as indicators of the vertical distributions of phytoplankton biomass, which was comparable between the surface and DCM layers. Water masses with different nutrient concentrations strongly controlled the variations of lipid biomarkers, showing high biomass and the dominance of diatoms in the eutrophic Oyashio region, whereas low biomass and high proportions of dinoflagellates and haptophytes occurred in the oligotrophic Kuroshio region. Diatoms predominated in the DCM, likely enhancing carbon sequestration in the deep ocean and in sediments. Our results quantitatively demonstrate the horizontal and vertical variations of phytoplankton biomass and community structure, leading to an improved understanding of ecosystem function and biogeochemical cycles in this important region of the NWPO.

How do precipitation events modify the stable isotope ratios in leaf water at Lhasa on the southern Tibetan Plateau? - Yong Wang; Wusheng Yu; Lun Luo; Minghui Li; Xiaoming Liu; Rong Guo; Yaoming Ma; Baiqing Xu; Guangjan Wu; Chengyi Zhao; Zhaowei Jing; Feili Wei; et al. (Isotopes in Environmental and Health Studies, 2022)

Ventromedial Thalamus-Projecting DCN Neurons Modulate Associative Sensorimotor Responses in Mice - Jie Zhang; Hao Chen; Li-Bin Zhang; Rong-Rong Li; Bin Wang; Qian-Hui Zhang; Liu-Xia Tong; Wei-Wei Zhang; Zhong-Xiang Yao; Bo Hu (Neuroscience Bulletin, 2022)

Identification and management of GCK-MODY complicating pregnancy in Chinese patients with gestational diabetes - Yanyan Jiang; Fusong Jiang; Ming Li; Qingkai Wu; Chenming Xu; Rong Zhang; Mingqiang Song; Yanzhong Wang; Ying Wang; Yating Chen; Juan Zhang; Xiaoxu Ge; et al. (Molecular and Cellular Biochemistry, 2022)

HucMSC-Ex alleviates inflammatory bowel disease via the lnc78583-mediated miR3202/HOXB13 pathway - Yuting Xu; Li Zhang; Dickson Kofi Wiredu Ocansey; Bo Wang; Yilin Hou; Rong Mei; Yongmin Yan; Xu Zhang; Zhaoyang Zhang; Fei Mao (Journal of Zhejiang University-SCIENCE B, 2022)

Phytoremediation of uranium-contaminated soil by perennial ryegrass (Lolium perenne L.) enhanced with citric acid application - Lishan Rong; Shiqi Zhang; Jiali Wang; Shiyou Li; Shuibo Xie; Guohua Wang (Environmental Science and Pollution Research, 2022)

The solar wind plasma upstream of Mars observed by Tianwen-1: Comparison with Mars Express and MAVEN - Kai Fan; Limei Yan; Yong Wei; Aibing Zhang; Linggao Kong; Markus Fränz; Fei He; Lihui Chai; Chongjing Yuan; Yuqi Wang; Jun Zhong; Zhaojin Rong; et al. (Science China Earth Sciences, 2022)

Cassiterite oxygen isotopes in magmatic-hydrothermal systems: in situ microanalysis, fractionation factor, and applications - Yang Li; Sheng He; Rong-Qing Zhang; Xian-Wu Bi; Lian-Jun Feng; Guo-Qiang Tang; Wen-Zhong Wang; Fang Huang; Xian-Hua Li (Mineralium Deposita, 2022)

Origin of Dispersed Organic Matter within Sandstones and Its Implication for Uranium Mineralization: A Case Study from Dongsheng Uranium Ore Filed in China - Fan Zhang; Yangquan Jiao; Shuangming Wang; Liqun Wu; Hui Rong (Journal of Earth Science, 2022)

Novel blood-based hypomethylation of SH3BP5 is associated with very early-stage lung adenocarcinoma - Rong Qiao; Runbo Zhong; Chunlan Liu; Feifei Di; Zheng Zhang; Ling Wang; Tian Xu; Yue Wang; Liping Dai; Wanjian Gu; Baohui Han; Rongxi Yang (Genes & Genomics, 2022)

Experimental Study on Mechanical Properties of Highly Swelling Soft Rocks in the Yanji Basin, Northern China - Rong Zhao; Xiong Wu; Ge Zhu; Xiaolei Wang; Aoshuang Mei; Xiao Zhang (Rock Mechanics and Rock Engineering, 2022)

The establishment of giant panda (Ailuropoda melanoleuca) fibroblast cell line - Yuliang Liu; Jiasong Chen; Tongying Feng; Rong Hou; Zhigang Cai; Donghui Wang; Mingyue Zhang; Yuan Li; Yijiao Chen; Junhui An (In Vitro Cellular & Developmental Biology - Animal, 2022)

QTL mapping integrated with BSA-Seq analysis identifies a novel gene conferring resistance to brown planthopper from common wild rice (Oryza rufipogon Griff.) - Xuan Wang; Yue Han; Yue-xiong Zhang; Biao Deng; Bi-qiu Wu; Xin-ying Guo; Yu-fen Qin; Yao-yu Fang; Fang Liu; Bao-xiang Qin; Ji-jing Luo; Rong-bai Li (Euphytica, 2022)

Sediment Resuspension as a Major Contributor to Sinking Particles in the Northwestern South China Sea: Evidence From Observations and Modeling - Lihua Ran; Wentao Ma; Martin G. Wiesner; Yuntao Wang; Jianfang Chen; Lanlan Zhang; Zhi Yang; Jingjing Zhang; Hongliang Li; Jian Ren; Rong Xiang; Erick Fredj (Frontiers in Marine Science, 2022)
The lateral advection of sinking particles is a well-known phenomenon in the South China Sea (SCS) and has a significant impact on the estimation of the efficiency of the biological carbon pump. However, little is known about the sources and pathways of sinking particles. Here, we present benthic and freshwater diatom fluxes and relative abundances collected by a sediment trap deployed at a water depth of 1,000 m and more than 500 m above the seafloor in the northwestern SCS, indicating that laterally transported resuspended sediment accounts for a significant part of the particle flux to the deep sea. A Lagrangian particle tracking model (LPTM) revealed that the resuspended particles likely originated from the neighboring continental slope, approximately 12–145 km to the west of the study site. Sediment trap observations and the LPTM together indicated that the impact of resuspended sediment occurred mainly in the deep water, and especially strong sediment resuspension was related to summer monsoon-induced coastal upwelling. The results suggest that particle resuspension has an important impact on the biological pump as well as on paleoenvironmental reconstructions of the SCS.

Activation of Autophagy Ameliorates Age-Related Neurogenesis Decline and Neurodysfunction in Adult Mice - Na Yang; Xueqin Liu; Xiaojie Niu; Xiaoqiang Wang; Rong Jiang; Na Yuan; Jianrong Wang; Chengwu Zhang; Kah-Leong Lim; Li Lu (Stem Cell Reviews and Reports, 2022)

Necrostatin-1 Relieves Learning and Memory Deficits in a Zebrafish Model of Alzheimer’s Disease Induced by Aluminum - Xiaocheng Gao; Ping Zhang; Jianping Chen; Lan Zhang; Nan Shang; Jin Chen; Rong Fan; Yanhong Wang; Tao Huang; Qiao Niu; Qinli Zhang (Neurotoxicity Research, 2022)

Mass cultivation of conidia of Pyricularia oryzae - Zhong-na Hao; Hai-ping Qiu; Zhen Zhang; Rong-yao Chai; Shi-zhen Wang; Yan-li Wang; Jiao-yu Wang; Guo-chang Sun (Journal of Plant Pathology, 2022)

Correction to: A native Trichoderma harzianum strain Th62 displays antagonistic activities against phytopathogenic fungi and promotes the growth of Celosia cristata - Xue-Yue Hou; Yue-Feng Wang; Chuan-Ying Jiang; Tong-Tong Zhai; Rui Miao; Jun-Jie Deng; Zhi-Hong Yao; Rong-Shu Zhang (Horticulture, Environment, and Biotechnology, 2022)

Association Between Essential Metal Elements and the Risk of Autism in Chinese Han Population - Jiahui Ma; Jing Wu; Haibin Li; Jingyu Wang; Jisheng Han; Rong Zhang (Biological Trace Element Research, 2022)

Epidemiological investigation and genetic characterization of porcine astrovirus genotypes 2 and 5 in Yunnan province, China - Keqing Ren; Rong Wang; Xiao Liu; Yinghua Liu; Jintao Zhang; Junyu Bi; Lianfeng Zhao; Zhigang Guo; Jianping Liu; Gefen Yin (Archives of Virology, 2022)

Human impacts alter driver–response relationships in lakes of Southwest China - Wenxiu Zheng; Enlou Zhang; Rong Wang; Peter Guy Langdon (Limnology and Oceanography, 2022)
Biodiversity and ecological stability are closely linked, and over recent timescales, anthropogenic impacts have accelerated losses in both from local to global scales. We attempt to show the combined response of diversity and stability of an aquatic community to changes in human activity as a driver. To address this, we measured the diversity and variability of chironomids and their drivers and nature of response to external conditions over the last century, based on 4 lake sediment sequences from Southwest China, one of world's 36 biodiversity hotspots. Our results showed that the driver–response relationship was linear in a lake without direct human impacts but nonlinear in human directly impacted lakes. Recent decreases in alpha diversity and increases in beta diversity were commonly recorded in all four lakes, suggesting that both species loss and a faster replacement of chironomid taxa are a regional phenomenon. However, in the same context of human‐induced global warming, increased variability and regime shifts only occurred in lowland lakes, directly disturbed by humans, highlighting that direct human impacts have overcome natural forcing as the determinant driver shaping the chironomid composition in these sites. In addition, we found that increases in beta diversity occurred prior to a regime shift and its character depends on how the community responds to the key external pressure. Our findings reveal that direct human disturbances have largely reshaped the chironomid composition and induced an earlier regime shift at the cost of species loss, resilience loss, and a change in driver–response type.

The Sources and Burial of Marine Organic Carbon in the Eastern China Marginal Seas - Yali Cao; Rong Bi; Xingchen Wang; Xi Chen; Jingwen Hu; Yaoyao Wang; Yiqing Jiang; Hailong Zhang; Lei Xing; Meixun Zhao (Frontiers in Marine Science, 2022)
The ecological functions and biogeochemical processes of continental marginal seas are important for the global carbon cycle. In the eastern China marginal seas (ECMS), phytoplankton productivity has increased significantly in recent decades, but the sources and burial processes of marine organic carbon (OC) remain under-studied. We analyzed the contents of marine lipid biomarkers (brassicasterol, dinosterol, and C 37 alkenones) in surface suspended particles obtained from seven cruises between 2010 and 2015, and in surface sediments from eight cruises between 2006 and 2012 in the ECMS, to estimate marine OC sources and burial. The correlations between lipid biomarkers and environmental factors were quantified to reveal controlling factors. The study area was divided into four regions according to cluster analysis conducted based on sediment parameters. Our results showed that the concentrations of marine lipid biomarkers in surface water were high near large estuaries such as the Changjiang River Estuary and the Yellow River Estuary, but those in surface sediments were high in mud areas. Nutrient concentration was a key factor controlling phytoplankton biomass in surface water, with high nutrients enhancing the growth of diatoms and dinoflagellates, while haptophytes were more abundant in low-nutrient, high-salinity and cold environments. High marine OC contents calculated from total OC δ 13 C were mainly associated with fine sediments transported by coastal currents, and finally deposited in mud areas. The proto-burial efficiency of marine OC in the ECMS (7–19%) was markedly higher than the mean value in global marginal seas, with high values being located in the western coast of the ECMS. The proto-burial efficiency of total marine lipid biomarkers (6–24%) was quantified for the first time in our study, with overall values and spatial patterns similar to that of marine OC. A key parameter for marine OC and marine biomarker proto-burial efficiency was sediment grain size. The smaller the sediment grain size was, the better the marine OC and marine biomarker were retained. Our study provides an important basis to elucidate spatial distribution patterns and forcing mechanisms of marine OC in surface water (production process) and surface sediments (burial process), and to estimate carbon budgets in large marginal seas.

Sampling Designs for Monitoring Ichthyoplankton in the Estuary Area: A Case Study on Coilia mystus in the Yangtze Estuary - Xiangyu Long; Rong Wan; Zengguang Li; Dong Wang; Pengbo Song; Fan Zhang (Frontiers in Marine Science, 2022)
A fishery-independent survey can provide detailed information for fishery assessment and management. However, the sampling design for the survey on ichthyoplankton in the estuary area is still poorly understood. In this study, we developed six stratified schemes with various sample sizes, attempting to find cost-efficient sampling designs for monitoring Coilia mystus ichthyoplankton in the Yangtze Estuary. The generalized additive model (GAM) with the Tweedie distribution was used to quantify the “true” distribution of C. mystus eggs and larvae, based on the data from the fishery-independent survey in 2019–2020. The performances of different sampling designs were evaluated by relative estimation error (REE), relative bias (RB), and coefficient of variation (CV). The results indicated that appropriate stratifications with intra-stratum homogeneity and inter-stratum heterogeneity could improve precision. The stratified schemes should be divided not only between the North Branch and South Branch but between river and sea. No less than two stratifications in the South Branch could also get better performance. The sample sizes of 45–55 were considered as the cost-efficient range. Compared to other monitoring programs, monitoring ichthyoplankton in the estuary area required a more complex stratification and a higher resolution sampling. The design ideology and optimization methodology in our study would provide references to sampling designs for ichthyoplankton in the estuary area.

Caffeine Inhibits Activation of the NLRP3 Inflammasome via Autophagy to Attenuate Microglia-Mediated Neuroinflammation in Experimental Autoimmune Encephalomyelitis - Hui-Qi Wang; Kai-Yi Song; Jin-Zhou Feng; Si-Yuan Huang; Xiu-Ming Guo; Lei Zhang; Gang Zhang; Ying-Chao Huo; Rong-Rong Zhang; Yue Ma; Qing-Zhe Hu; Xin-Yue Qin (Journal of Molecular Neuroscience, 2022)

Promotional effect of ZrO2 and WO3 on bimetallic Pt-Pd diesel oxidation catalyst - Rongrong Fan; Zhaoqiang Li; Yu Wang; Yan Wang; Zhiyong Ding; Cheng Zhang; Na Kang; Xin Guo; Rong Wang (Environmental Science and Pollution Research, 2022)

Stress response mechanisms and description of three novel species Shewanella avicenniae sp. nov., Shewanella sedimentimangrovi sp. nov. and Shewanella yunxiaonensis sp. nov., isolated from mangrove ecosystem - Guo-Hong Liu; Qi Zhang; Manik Prabhu Narsing Rao; Shang Yang; Rong Tang; Huai Shi; Jie-Ping Wang; Guan-Min Huang; Bo Liu; Shun-Gui Zhou; Wen-Jun Li (Antonie van Leeuwenhoek, 2021)

Use of historical and contemporary distribution of mammals in China to inform conservation - Kang Huang; He Zhang; Chengliang Wang; Rong Hou; Pei Zhang; Gang He; Songtao Guo; Shiyi Tang; Baoguo Li; Charles Oxnard; Ruliang Pan (Conservation Biology, 2021)
A systematic understanding of dynamic animal extinction trajectories for different regions in a nation like China is critically important to developing practical conservation strategies. We explored historical and contemporary changes in terrestrial mammalian diversity to determine how diversity in each of the 5 regions in China has changed over time and to examine the conservation potential of these regions. We used records from databases on Pleistocene mammalian fossils and historical distribution records (1175–2020) for Primates (as a case study) to reconstruct evolutionary and historical distribution trajectories of the 11 orders of terrestrial mammals and to predict their prospective survival based on the national conservation strategy applied. The results indicated that since the Pleistocene, 4–5 mammalian orders have been lost in the northeast, 3 in central China, 2 along the coast, and 1 in the northwest. In the southwest, all 11 orders were maintained. Contemporarily, the coast and southwest had the highest and second‐highest species densities. The southwest region and southeastern sections of the northwest region were the most historically and contemporarily diverse areas, which suggests that they should be the first priority for protected area (PA) designation. The central and coastal areas should be secondarily prioritized. In these 2 regions, conservation should focus on human coexistence with nature. Less attention should be paid to the PA in the northeast and western northwest because in these areas ecosystems are depauperate and the climate is harsh. Conservation in these areas should focus principally on avoiding further human encroachment on natural areas. Article impact statement : Historical and contemporary patterns of extinction can be a basis for mammalian conservation strategies.

The Non-stationary Environmental Effects on Spawning Habitat of Fish in Estuaries: A Case Study of Coilia mystus in the Yangtze Estuary - Dong Wang; Rong Wan; Zengguang Li; Junbo Zhang; Xiangyu Long; Pengbo Song; Lu Zhai; Shuo Zhang (Frontiers in Marine Science, 2021)
The estuarine areas provide necessary spawning habitat, nursing habitat, and migratory for a variety of fishes and the environmental conditions are of significant heterogeneity. Coilia mystus is the key commercial fish that spawns in the Yangtze Estuary and the yield has declined sharply in the past 30 years. In order to understand the spawning habitat selection mechanism of C. mystus , the geographically weighted regression (GWR) model was applied to explore the non-stationary effect of environmental variables [e.g., the sea surface temperature (SST) and the sea surface salinity (SSS)] and geographical variables [e.g., the distance to the coast (DTC) and the depth (DEP) of water] on the egg density distribution of C. mystus . The data were derived from the spring and summer ichthyoplankton surveys carried out from 2019 to 2020 in the Yangtze Estuary, China. The GWR model results showed that the key variables in different seasons had spatial non-stationary effects on the distribution of spawning habitat of C. mystus , which were mainly caused by regional rise in temperature and saltwater intrusion of the South Branch. In the spring, the SSS, the DTC, and the DEP were the main impact factors and saltwater intrusion in the South Branch might lead to the trend that the spawning habitat moved further upstream to the Changxing Island. The SST was most important in the summer and the relatively lower SST was more crucial in the spawning habitat selection than the DTC and the DEP. The GWR model performed well in the study of C. mystus potential spawning habitat in the Yangtze Estuary. We recommend that more attention should be paid in regional variation of environmental factors to explore fish potential spawning habitat in the estuarine areas.

Differences in pathogenicity and physiologic races between Pyricularia oryzae isolates from indica and japonica rice varieties - Zhong-na Hao; Zhen Zhang; Hai-ping Qiu; Rong-yao Chai; Shi-zhen Wang; Yan-li Wang; Jiao-yu Wang; Guo-chang Sun (Journal of Plant Pathology, 2021)

Mortality risk attributable to diurnal temperature range: a multicity study in Yunnan of southwest China - Yujin Wang; Yang Chen; Jiaqi Chen; Rong Wu; Pi Guo; Shun Zha; Qingying Zhang (Environmental Science and Pollution Research, 2021)

Motor Circuit and Superior Temporal Sulcus Activities Linked to Individual Differences in Multisensory Speech Perception - Liyuan Li; Rong Li; Xinju Huang; Fei Shen; Hongyu Wang; Xuyang Wang; Chijun Deng; Chong Wang; Jiale Yang; Leiyao Zhang; Jiyi Li; Ting Zou; et al. (Brain Topography, 2021)

Lignans and phenylpropanoids from the liquid juice of phyllostachys edulis - De-Tao Wang; Ying-Ying Xue; Ying-Fang Zhang; Hang Xun; Qi-Rong Guo; Feng Tang; Jia Sun; Fei-Fei Qi (Natural Product Research, 2021)

Development and application of the Faba_bean_130K targeted next-generation sequencing SNP genotyping platform based on transcriptome sequencing - Chenyu Wang; Rong Liu; Yujiao Liu; Wanwei Hou; Xuejun Wang; Yamei Miao; Yuhua He; Yu Ma; Guan Li; Dong Wang; Yishan Ji; Hongyan Zhang; et al. (Theoretical and Applied Genetics, 2021)

CARMA1 is required for Notch1-induced NF-κB activation in SIL-TAL1-negative T cell acute lymphoblastic leukemia - Ninghan Zhang; Jiawen Xu; Rong Wang; Ting Pan; Huanxin Zhang; Lingling Yin; Yao Yao; Linyan Xu; Shengyun Zhu; Qingyun Wu; Zhenyu Li; Xuejiao Liu; et al. (Journal of Molecular Medicine, 2021)

Comparison of mitochondrial genomes provides insights into intron dynamics and evolution in Botryosphaeria dothidea and B . kuwatsukai - Bo Wang; Xiaofei Liang; Xiaojuan Hao; Haiyue Dang; Tom Hsiang; Mark L. Gleason; Rong Zhang; Guangyu Sun (Environmental Microbiology, 2021)
Summary Botryosphaeria dothidea is one of the most common fungal pathogens on a large number of hosts worldwide. Botryosphaeria dothidea and B. kuwatsukai are also the main causal agents of apple ring rot. In this study, we sequenced, assembled and annotated the circular mitogenomes of 12 diverse B . dothidea isolates (105.7–114.8 kb) infecting various plants including apple, and five diverse B . kuwatsukai isolates (118.0–124.6 kb) from apple. B . dothidea mitogenomes harboured a set of 29–31 introns and 48–52 ORFs. In contrast, B . kuwatsukai mitogenomes harboured more introns (32–34) and ORFs (51–54). The variation in mitogenome sizes was associated mainly with different numbers of introns and insertions of mobile genetic elements. Interestingly, B . dothidea and B . kuwatsukai displayed distinct intron distribution patterns, with three intron loci showing presence/absence dynamics in each species. Large numbers of introns (57% in B . dothidea and 49% in B . kuwatsukai ) were most likely obtained through horizontal transfer from non‐Dothideomycetes. The mitochondrial gene phylogeny supported the differentiation of the two species. Overall, this study sheds light into the mitochondrial evolution of the plant pathogens B . dothidea and B . kuwatsukai , and intron distribution patterns could be useful markers for studies on population diversity.

A stable QTL qSalt-A04-1 contributes to salt tolerance in the cotton seed germination stage - Qishen Gu; Huifeng Ke; Chenchen Liu; Xing Lv; Zhengwen Sun; Zhengwen Liu; Wei Rong; Jun Yang; Yan Zhang; Liqiang Wu; Guiyin Zhang; Xingfen Wang; et al. (Theoretical and Applied Genetics, 2021)

Hydrated halloysite: the pesky stuff responsible for a cascade of landslides triggered by the 2018 Iburi earthquake, Japan - Fawu Wang; Shuai Zhang; Ran Li; Rong Zhou; Andreas Auer; Hiroto Ohira; Zili Dai; Tetsuya Inui (Landslides, 2021)

Evaluation of field resistance to brown stripe disease in novel and major cultivated sugarcane varieties in China - Xiao-Yan Wang; Xiao-Yan Cang; Wei Qin; Hong-Li Shan; Rong-Yue Zhang; Chang-Mi Wang; Wen-Feng Li; Ying-Kun Huang (Journal of Plant Pathology, 2021)

Effects of Mn2+ on neutral lipid content, C4 pathway, and related gene expression in Phaeodactylum tricornutum - Rong-Shi Chen; Li Zhang; Feng-Juan Wei; Lan-Ying Yuan; Pu Zhao; He-Yu Wang; Yi-Fu Gong (Journal of Applied Phycology, 2021)

Exposure to antibiotics and mental disorders in children: a community-based cross-sectional study - Jingjing Zhang; Kaiyong Liu; Liang Sun; Linsheng Yang; Xinji Liu; Yitian Zhu; Rong Wei; Zhongxiu Jin; Li Wang; Ying Ma; Sufang Wang; Annuo Liu; et al. (Environmental Geochemistry and Health, 2021)

A temperature-induced chitosanase bacterial cell-surface display system for the efficient production of chitooligosaccharides - Qianqian Li; Tuantuan Wang; Yangzhi Ye; Shimin Guan; Baoguo Cai; Shuo Zhang; Shaofeng Rong (Biotechnology Letters, 2021)

Oceanobacillus salinisoli sp. nov., a bacterium isolated from saline soil of Turpan city in Xinjiang province, north–west China - Wen-Yong Zhu; Li Yang; Zhou-Tian-Le Zhang; Chang-Gai Mu; Yun Wang; Ya-Rong Kou; Gang-Qiang Jiang; Min Yin; Shu-Kun Tang (Archives of Microbiology, 2021)

YAP promotes ocular neovascularization by modifying PFKFB3-driven endothelial glycolysis - Yifan Feng; Rong Zou; Xi Zhang; Minqian Shen; Xiuping Chen; Jing Wang; Weiran Niu; Yuanzhi Yuan; Fei Yuan (Angiogenesis, 2021)

Surfactant-assisted adsorption of uranyl ions in aqueous solution on TiO2/polythiophene nanocomposite - Youqun Wang; Yinghui Xie; Zhiyang Zheng; Dejun Zeng; Ying Dai; Zhibin Zhang; Xiaohong Cao; Rong Zou; Yunhai Liu (Environmental Science and Pollution Research, 2021)

Retrospective surveillance of porcine circovirus 4 in pigs in Inner Mongolia, China, from 2016 to 2018 - Zhuo Ha; Chengdong Yu; Changzhan Xie; Guanyu Wang; Ying Zhang; Pengfei Hao; Jinfeng Li; Zhuoxin Li; Yanwei Li; Fulong Rong; Fulong Nan; He Zhang; et al. (Archives of Virology, 2021)

Transcutaneous Auricular Vagus Nerve Stimulation: From Concept to Application - Yu Wang; Shao-Yuan Li; Dan Wang; Mo-Zheng Wu; Jia-Kai He; Jin-Ling Zhang; Bin Zhao; Li-Wei Hou; Jun-Ying Wang; Lei Wang; Yi-Fei Wang; Yue Zhang; et al. (Neuroscience Bulletin, 2021)

Syntheses and anticancer activities of novel glucosylated (−)-epigallocatechin-3-gallate derivatives linked via triazole rings - Bo-Ya Shi; Ze-Hao Wang; Ning Zhang; Yin-Rong Xie; Xiu-Li Sun; Hao-Nan Yang; Yi-Long Wu; Cheng-Ting Zi; Xuan-Jun Wang; Jun Sheng (Medicinal Chemistry Research, 2021)

Mucor rongii sp. nov., a New Cold-Tolerant Species from China - Feirong Bai; Su Yao; Chengshan Cai; Tianci Zhang; Yu Wang; Wei Liu; Baowen Ma; Changyuan Rong; Chi Cheng (Current Microbiology, 2021)

Coupling ocean–atmosphere intensity determines ocean chlorophyll-induced SST change in the tropical Pacific - Feng Tian; Rong-Hua Zhang; Xiujun Wang (Climate Dynamics, 2021)

Dietary Supplementation with Sea Cucumber Saponins and Exercise Can Significantly Suppress Adipose Accumulation in Mice Fed with High-Fat Diet - Rong Li; Jing Meng; Haohao Shi; Chengcheng Wang; Zhaojie Li; Changhu Xue; Yuming Wang; Tiantian Zhang (Journal of Ocean University of China, 2021)

Simplified calculation method for cumulative deformations of marine structured clay under cyclic loading - Meng Zang; Ling-wei Kong; Rong-tang Zhang; Wei-wei Wang (Arabian Journal of Geosciences, 2021)

Mesoscale wind stress-SST coupling induced feedback to the ocean in the western coast of South America - Chaoran Cui; Rong-Hua Zhang; Yanzhou Wei; Hongna Wang (Journal of Oceanology and Limnology, 2021)

Effect of fermentation bed on bacterial growth in the fermentation mattress material and cecum of ducks - Jian- mei Wang; Xin- meng Gan; Fa-jun Pu; Wan- xia Wang; Min Ma; Ling-li Sun; Ji-wei Hu; Bo Hu; Rong-ping Zhang; Li-li Bai; Liang Li; He-he Liu (Archives of Microbiology, 2021)

Genome-wide identification and characterization of long non-coding RNAs involved in flag leaf senescence of rice - Xiaoping Huang; Hongyu Zhang; Qiang Wang; Rong Guo; Lingxia Wei; Haiyan Song; Weigang Kuang; Jianglin Liao; Yingjin Huang; Zhaohai Wang (Plant Molecular Biology, 2021)
Key message This study showed the systematic identification of long non-coding RNAs (lncRNAs) involving in flag leaf senescence of rice, providing the possible lncRNA-mRNA regulatory relationships and lncRNA-miRNA-mRNA ceRNA networks during leaf senescence. Abstract LncRNAs have been reported to play crucial roles in diverse biological processes. However, no systematic identification of lncRNAs associated with leaf senescence in plants has been studied. In this study, a genome-wide high throughput sequencing analysis was performed using rice flag leaves developing from normal to senescence. A total of 3953 lncRNAs and 38757 mRNAs were identified, of which 343 lncRNAs and 9412 mRNAs were differentially expressed. Through weighted gene co-expression network analysis (WGCNA), 22 continuously down-expressed lncRNAs targeting 812 co-expressed mRNAs and 48 continuously up-expressed lncRNAs targeting 1209 co-expressed mRNAs were considered to be significantly associated with flag leaf senescence. Gene Ontology results suggested that the senescence-associated lncRNAs targeted mRNAs involving in many biological processes, including transcription, hormone response, oxidation–reduction process and substance metabolism. Additionally, 43 senescence-associated lncRNAs were predicted to target 111 co-expressed transcription factors. Interestingly, 8 down-expressed lncRNAs and 29 up-expressed lncRNAs were found to separately target 12 and 20 well-studied senescence-associated genes (SAGs). Furthermore, analysis on the competing endogenous RNA (CeRNA) network revealed that 6 down-expressed lncRNAs possibly regulated 51 co-expressed mRNAs through 15 miRNAs, and 14 up-expressed lncRNAs possibly regulated 117 co-expressed mRNAs through 21 miRNAs. Importantly, by expression validation, a conserved miR164-NAC regulatory pathway was found to be possibly involved in leaf senescence, where lncRNA MSTRG.62092.1 may serve as a ceRNA binding with miR164a and miR164e to regulate three transcription factors. And two key lncRNAs MSTRG.31014.21 and MSTRG.31014.36 also could regulate the abscisic-acid biosynthetic gene BGIOSGA025169 ( OsNCED4 ) and BGIOSGA016313 (NAC family) through osa-miR5809. The possible regulation networks of lncRNAs involving in leaf senescence were discussed, and several candidate lncRNAs were recommended for prior transgenic analysis. These findings will extend the understanding on the regulatory roles of lncRNAs in leaf senescence, and lay a foundation for functional research on candidate lncRNAs.

Involvement of Mitophagy in Aluminum Oxide Nanoparticle–Induced Impairment of Learning and Memory in Mice - Tao Huang; Weiwei Guo; Yanhong Wang; Lijun Chang; Nan Shang; Jin Chen; Rong Fan; Lan Zhang; Xiaocheng Gao; Qiao Niu; Qinli Zhang (Neurotoxicity Research, 2021)

A native Trichoderma harzianum strain Th62 displays antagonistic activities against phytopathogenic fungi and promotes the growth of Celosia cristata - Xue-Yue Hou; Yue-Feng Wang; Chuan-Ying Jiang; Tong-Tong Zhai; Rui Miao; Jun-Jie Deng; Zhi-Hong Yao; Rong-Shu Zhang (Horticulture, Environment, and Biotechnology, 2021)

Clinical and microbiological characteristics of adults with hospital-acquired pneumonia: a 10-year prospective observational study in China - Yuyao Yin; Chunjiang Zhao; Henan Li; Longyang Jin; Qi Wang; Ruobing Wang; Yawei Zhang; Jiangang Zhang; Hui Wang; Chunxia Yang; Bin Cao; Yingmei Liu; et al. (European Journal of Clinical Microbiology & Infectious Diseases, 2021)

Comparative Transcriptomic Analyses of Haemophilus parasuis Reveal Differently Expressed Genes among Strains with Different Virulence Degrees - Yuan Y. Zhou; Chao Wang; Jing Yuan; Rong L. Yin; Xin Chen; Rui Li; Xue L. Zhang; Jing Wang; Chen Huang; Rong H. Yin (Current Microbiology, 2021)

Marinobacter shengliensis subsp. alexandrii Subsp. Nov., Isolated from Cultivable Phycosphere Microbiota of Highly Toxic Dinoflagellate Alexandrium catenella LZT09 and Description of Marinobacter shengliensis Subsp. shengliensis Subsp. Nov - Xi Yang; Rong Xiang; Nurhezreen Md Iqbal; Yu-Han Duan; Xiao-Ai Zhang; Lei Wang; Lin-Zeng Yu; Jia-Zhou Li; Ming-Fei Sun; Qiao Yang; Chun-Tian Zheng; Shen-Quan Liao (Current Microbiology, 2021)

Development of a Microfluidics-Based Quantitative Real-Time PCR to Rapidly Identify Photobacterium damselae subsp. damselae with Different Pathogenicity by Detecting the Presence of mcp or dly Gene - Zheng Zhang; Yongxiang Yu; Jing Chen; Yingeng Wang; Yong Jiang; Meijie Liao; Xiaojun Rong; Hao Zhang (Journal of Ocean University of China, 2021)

Chlamydia trachomatis induces autophagy by p62 in HeLa cell - Fuyan Wang; Hongbo Zhang; Xiaofang Lu; Quan Zhu; Tingting Shi; Rong Lu; Ping Yu; Lei Zhang; Yong Wang (World Journal of Microbiology and Biotechnology, 2021)

Effects of simulated drought stress on carotenoid contents and expression of related genes in carrot taproots - Rong-Rong Zhang; Ya-Hui Wang; Tong Li; Guo-Fei Tan; Jian-Ping Tao; Xiao-Jun Su; Zhi-Sheng Xu; Yong-Sheng Tian; Ai-Sheng Xiong (Protoplasma, 2021)

Retraction Note: Fibrauretine reduces ischemia/reperfusion injury via RISK/eNOS activation - Chunsheng Wang; Rong Chang; Gan Gao; Xing Liu; Yingwei Zhang (Naunyn-Schmiedeberg's Archives of Pharmacology, 2021)

Knockdown of Arginyl-tRNA Synthetase Attenuates Ischemia-Induced Cerebral Cortex Injury in Rats After Middle Cerebral Artery Occlusion - Yang Liu; Xue-Bin Hu; Li-Zhi Zhang; Zi Wang; Rong Fu (Translational Stroke Research, 2021)
Some researchers have previously shown that RNAi knockdown of arginyl-tRNA synthetase (ArgRS) before or after a hypoxic injury can rescue animals from death, based on the model organism, C. elegans . However, there has been no study on the application of arginyl-tRNA synthetase knockdown in treating mammalian ischemic stroke, and its potential mechanism and effect on ischemic brain damage are still unknown. Here, we focused on the Rars gene, which encodes an arginyl-tRNA synthetase, and examined the effects of Rars knockdown in a permanent middle cerebral artery occlusion model in rats. To achieve this aim, adult male Sprague-Dawley (SD) rats were given right cerebral cortex injections of short hairpin RNA (shRNA) adenovirus (AV) particles to knock down arginyl-tRNA synthetase, and a non-targeting control (NTC) vector or phosphate-buffered solution served as the controls. After 4 days, the rats were exposed to permanent middle cerebral artery occlusion (pMCAO). Then, the right cerebral cortex level of arginyl-tRNA synthetase was examined, and the effects of the Rars knockdown were evaluated by differences in infarction volume, oxidative stress, blood-brain barrier, mitochondrial function, and glucose metabolism at 1 day and 3 days after MCAO. The injection of shRNA adenovirus particles successfully suppressed the expression of arginyl-tRNA synthetase in the cerebral cortex. We observed an improvement in oxidative stress, mitochondrial function, and glucose utilization and a reduction in brain edema compared with the non-targeting control rats with suppressed expression of arginyl-tRNA synthetase mRNA in the ipsilateral ischemic cortex of the brain. Our findings indicate that knockdown of arginyl-tRNA synthetase in the cerebral cortex exerted neuroprotective effects, which were achieved not only by the improvement of oxidative stress and glucose utilization but also by the maintenance of mitochondrial morphological integrity and the preservation of mitochondrial function. Knockdown of ArgRS administration could be a promising approach to protect ischemic stroke.

Small RNA Sequencing Analysis of Germinating Single-bud Seedcane Sett in Sugarcane - Kai-Chao Wu; Lin Xu; Zhi-Nian Deng; Tian Pang; Rong-Hua Zhang; Yi-Jie Li; Xiao-Yan Liu; Cheng-Feng Huang; Wen-Xian Qin; Jian-Feng Wei; Li-Ping Wei; Yang-Rui Li; et al. (Sugar Tech, 2021)

Systematic identification and characterization of circular RNAs involved in flag leaf senescence of rice - Xiaoping Huang; Hongyu Zhang; Rong Guo; Qiang Wang; Xuanzhi Liu; Weigang Kuang; Haiyan Song; Jianglin Liao; Yingjin Huang; Zhaohai Wang (Planta, 2021)
Main conclusion Circular RNAs (circRNAs) identification, expression profiles, and construction of circRNA-parental gene relationships and circRNA-miRNA-mRNA ceRNA networks indicate that circRNAs are involved in flag leaf senescence of rice. Abstract Circular RNAs (circRNAs) are a class of 3′-5′ head-to-tail covalently closed non-coding RNAs which have been proved to play important roles in various biological processes. However, no systematic identification of circRNAs associated with leaf senescence in rice has been studied. In this study, a genome-wide high-throughput sequencing analysis was performed using rice flag leaves developing from normal to senescence. Here, a total of 6612 circRNAs were identified, among which, 113 circRNAs were differentially expressed (DE) during the leaf senescence process. Moreover, 4601 (69.59%) circRNAs were derived from the exons or introns of their parental genes, while 2110 (71%) of the parental genes produced only one circRNA. The sequence alignment analysis showed that hundreds of rice circRNAs were conserved among different plant species. Gene Ontology (GO) enrichment analysis revealed that parental genes of DE circRNAs were enriched in many biological processes closely related to leaf senescence. Through weighted gene co-expression network analysis (WGCNA), six continuously down-expressed circRNAs, 18 continuously up-expressed circRNAs and 15 turn-point high-expressed circRNAs were considered to be highly associated with leaf senescence. Additionally, a total of 17 senescence-associated circRNAs were predicted to have parental genes, in which, regulations of three circRNAs to their parental genes were validated by qRT-PCR. The competing endogenous RNA (ceRNA) networks were also constructed. And a total of 11 senescence-associated circRNAs were predicted to act as miRNA sponges to regulate mRNAs, in which, regulation of two circRNAs to eight mRNAs was validated by qRT-PCR. It is discussed that senescence-associated circRNAs were involved in flag leaf senescence probably through mediating their parental genes and ceRNA networks, to participate in several well-studied senescence-associated processes, mainly including the processes of transcription, translation, and posttranslational modification (especially protein glycosylation), oxidation–reduction process, involvement of senescence-associated genes, hormone signaling pathway, proteolysis, and DNA damage repair. This study not only showed the systematic identification of circRNAs involved in leaf senescence of rice, but also laid a foundation for functional research on candidate circRNAs.

Antidepressant Effect of Paeoniflorin Is Through Inhibiting Pyroptosis CASP-11/GSDMD Pathway - Dan-Dan Tian; Min Wang; An Liu; Mei-Rong Gao; Chen Qiu; Wen Yu; Wen-Ju Wang; Kun Zhang; Le Yang; Yan-Yan Jia; Chang-Bin Yang; Yu-Mei Wu (Molecular Neurobiology, 2021)

Rhizobium rhizolycopersici sp. nov., Isolated from the Rhizosphere Soil of Tomato Plants in China - Kyu Kyu Thin; Shan-Wen He; Xing Wang; Yao Wang; Ma Rong; Ji-Gang Han; Xiaoxia Zhang (Current Microbiology, 2021)

Study on Characteristics of Shear Modulus of Zhanjiang Structured Clay During Triaxial Shearing - Meng Zang; Ling-wei Kong; Rong-tang Zhang; Wei-wei Wang (Geotechnical and Geological Engineering, 2021)

Risk of congenital heart disease due to exposure to common electrical appliances during early pregnancy: a case-control study - Doudou Zhao; Leqian Guo; Ruo Zhang; Qixia Zhu; Hongli Wang; Rong Liu; Hong Yan; Shaonong Dang (Environmental Science and Pollution Research, 2021)

Heavy metal concentrations and associated health risks in edible tissues of marine nekton from the outer Pearl River Estuary, South China Sea - Chang-Ping Yang; Yan Liu; Bin-Bin Shan; Jing Xu; Wei Yu; Dian-Rong Sun; Zai-Wang Zhang (Environmental Science and Pollution Research, 2021)

Geochemical characteristics and geological significance of chert nodules in Qixia formation, Pingding Mountain, lower Yangtze Plate - Jun Li; Lu-wang Chen; Chun-ming Hao; Jie Zhang; Song Chen; He-rong Gui (Journal of Mountain Science, 2021)

Red elemental selenium (Se 0 ) improves the immunoactivities of EPC cells, crucian carp and zebrafish against spring viraemia of carp virus - Jinbao Tian; Yong Zhang; Rong Zhu; Yeqing Wu; Xiaoxiao Liu; Xingguo Wang (Journal of Fish Biology, 2021)
Selenium, as an essential trace element, interferes through selenoproteins in many physiological processes of plants and mammals. Its antiviral activity has recently attracted much attention because selenium improves the antiviral capacity of animal cells against a few viruses relevant to human diseases. In this study, the red elemental selenium was purified from the fermentative culture of Herbaspirillum camelliae WT00C and then used to culture epithelioma papulosum cyprinid (EPC) cells or feed crucian carp and zebrafish. Finally, its antiviral effects were investigated at the cell level and living fishes after spring viraemia of carp virus infection. At the cell level, 5, 10 and 20 μg ml –1 red elemental selenium significantly induced the expression of interferon ( IFN ) and ISG 15 genes in EPC cells. The viral TCID 50 (50% tissue culture infective dose) values in the EPC cells incubated with 5, 10 and 20 μg ml –1 red elemental selenium were significantly less than those of the control. More expression of IFN and ISG 15 genes and less TCID 50 values indicate that red elemental selenium indeed improves the antiviral capability of EPC cells. In the crucian carp fed with the food containing 5 and 10 μg g –1 red elemental selenium, IFN expressions showed 13‐ and 39‐fold increases at the 16th day of post‐injection, and its expression was dependent on selenium concentrations. Meanwhile, no fish death occurred in all the experimental groups. In the zebrafish fed with the red worm containing 5 μg g –1 red elemental selenium, IFN and Mx expressions and survival rate were significantly higher than those of the control. The results of this study show that red elemental selenium indeed improves the antiviral activity of fish. The antiviral effects of selenium mainly come from its immune regulation through its incorporation into selenoproteins. The optimum level of selenium contributes to improving fish immunity, whereas excess selenium causes excessive immune and inflammatory responses.

Phytochemical and antitumor studies on Cynanchum mongolicum (Maxim.) Kom - Yong-Cheng Yang; Yan-Ming Wang; Zi-Jian Rong; Li-Na Hong; Qian Zhang; Jing-Ming Jia; An-Hua Wang (Natural Product Research, 2020)

Mapping quantitative trait loci associated with stem-related traits in maize (Zea mays L.) - Qiqi Shang; Degui Zhang; Rong Li; Kaixin Wang; Zimeng Cheng; Zhiqiang Zhou; Zhuanfang Hao; Jinbao Pan; Xinhai Li; Liyu Shi (Plant Molecular Biology, 2020)

Quantitative Determination of Glymphatic Flow Using Spectrophotofluorometry - Yu Zhang; Jian Song; Xu-Zhong He; Jian Xiong; Rong Xue; Jia-Hao Ge; Shi-Yu Lu; Die Hu; Guo-Xing Zhang; Guang-Yin Xu; Lin-Hui Wang (Neuroscience Bulletin, 2020)

Lycium barbarum polysaccharide protects against Homocysteine-induced Vascular smooth muscle cell proliferation and phenotypic transformation via PI3K/Akt pathway - Minghao Zhang; Fan Li; Smritee Pokharel; Ting Ma; Xiuyu Wang; Yiyong Wang; Weirong Wang; Rong Lin (Journal of Molecular Histology, 2020)

Prenatal diagnosis and neonatal phenotype of a de novo microdeletion of 17p11.2p12 associated with Smith‒Magenis syndrome and external genital defects - Pingping Zhang; Yanmei Sun; Haishen Tian; Limin Rong; Fangna Wang; Xiaoping Yu; Yali Li; Jian Gao (Journal of Genetics, 2020)

The intestine of artificially bred larval turbot (Scophthalmus maximus) contains a stable core group of microbiota - Zheng Zhang; Yongxiang Yu; Yan Jiang; Yingeng Wang; Meijie Liao; Xiaojun Rong; Qian Liu (Archives of Microbiology, 2020)

FgPal1 regulates morphogenesis and pathogenesis in Fusarium graminearum - Jinrong Yin; Chaofeng Hao; Gang Niu; Wei Wang; Guanghui Wang; Ping Xiang; Jin‐Rong Xu; Xue Zhang (Environmental Microbiology, 2020)
Summary Ascospores are the primary inoculum in Fusarium graminearum , a causal agent of wheat head blight. In a previous study, FgPAL1 was found to be upregulated in the Fgama1 mutant and important for ascosporogenesis. However, the biological function of this well‐conserved gene in filamentous ascomycetes is not clear. In this study, we characterized its functions in growth, differentiation and pathogenesis. The Fgpal1 mutant had severe growth defects and often displayed abnormal hyphal tips. It was defective in infectious growth in rachis tissues and spreading in wheat heads. The Fgpal1 mutant produced conidia with fewer septa and more nuclei per compartment than the wild type. In actively growing hyphal tips, FgPal1‐GFP mainly localized to the subapical collar and septa. The FgPal1 and LifeAct partially co‐localized at the subapical region in an interdependent manner. The Fgpal1 mutant was normal in meiosis with eight nuclei in developing asci but most asci were aborted. Taken together, our results showed that FgPal1 plays a role in maintaining polarized tip growth and coordination between nuclear division and cytokinesis, and it is also important for infectious growth and developments of ascospores by the free cell formation process.

Divergence in flowering time is a major component contributing to reproductive isolation between two wild rice species (Oryza rufipogon and O. nivara) - Xun Xu; Qing-Lin Meng; Mu-Fan Geng; Ning-Ning Ren; Lian Zhou; Yu-Su Du; Zhe Cai; Mei-Xia Wang; Xin Wang; Xiu-Hua Wang; Jing-Dan Han; Shuai Jiang; et al. (Science China Life Sciences, 2020)

Cytokinin (6-benzylaminopurine) elevates lignification and the expression of genes involved in lignin biosynthesis of carrot - Ahmed Khadr; Ya-Hui Wang; Rong-Rong Zhang; Xin-Rui Wang; Zhi-Sheng Xu; Ai-Sheng Xiong (Protoplasma, 2020)

Small grain and semi-dwarf 3, a WRKY transcription factor, negatively regulates plant height and grain size by stabilizing SLR1 expression in rice - Jie Lan; Qibing Lin; Chunlei Zhou; Yakun Ren; Xi Liu; Rong Miao; Ruonan Jing; Changling Mou; Thanhliem Nguyen; Xingjie Zhu; Qian Wang; Xin Zhang; et al. (Plant Molecular Biology, 2020)

Identification, functional characterization, and estrogen regulation on gonadotropin-releasing hormone in the spotted scat, Scatophagus argus - Hua-pu Chen; Xue-fan Cui; Yao-rong Wang; Zhi-yuan Li; Chang-xu Tian; Dong-neng Jiang; Chun-Hua Zhu; Yong Zhang; Shui-sheng Li; Guang-li Li (Fish Physiology and Biochemistry, 2020)

Model test of the stability degradation of a prestressed anchored rock slope system in a corrosive environment - Cong Li; Rong-tang Zhang; Jie-bing Zhu; Zhi-jun Liu; Bo Lu; Bin Wang; Yu-zhou Jiang; Jie-sheng Liu; Ping Zeng (Journal of Mountain Science, 2020)

NLRP6 contributes to inflammation and brain injury following intracerebral haemorrhage by activating autophagy - Han Xiao; Hui Chen; Rong Jiang; Li Zhang; Lu Wang; Hui Gan; Ning Jiang; Jing Zhao; Xuan Zhai; Ping Liang (Journal of Molecular Medicine, 2020)

Changes in leaf vein traits among vein types of alpine grassland plants on the Tibetan Plateau - Chang-shun Wang; Wang-wang Lyu; Li-li Jiang; Shi-ping Wang; Qi Wang; Fan-dong Meng; Li-rong Zhang (Journal of Mountain Science, 2020)

Ice sheet controls on fine-grained deposition at the southern Mendeleev Ridge since the penultimate interglacial - Liming Ye; Xiaoguo Yu; Weiyan Zhang; Rong Wang (Acta Oceanologica Sinica, 2020)

Aluminum-Induced Cognitive Impairment and PI3K/Akt/mTOR Signaling Pathway Involvement in Occupational Aluminum Workers - Nan Shang; Ping Zhang; Shuo Wang; Jianping Chen; Rong Fan; Jin Chen; Tao Huang; Yanhong Wang; Jeremy Duncan; Ling Zhang; Qiao Niu; Qinli Zhang (Neurotoxicity Research, 2020)

RETRACTED ARTICLE: Fibrauretine reduces ischemia/reperfusion injury via RISK/eNOS activation - Chunsheng Wang; Rong Chang; Gan Gao; Xing Liu; Yingwei Zhang (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

Comparison of the effects of deep and moderate neuromuscular block on respiratory system compliance and surgical space conditions during robot-assisted laparoscopic radical prostatectomy: a randomized clinical study - Shao-jun Zhu; Xiao-lin Zhang; Qing Xie; Yan-feng Zhou; Kui-rong Wang (Journal of Zhejiang University-SCIENCE B, 2020)

Biochemical Toxicity and Potential Detoxification Mechanisms in Earthworms Eisenia fetida Exposed to Sulfamethazine and Copper - Hong Rong; Chengrun Wang; Haitao Liu; Min Zhang; Yueting Yuan; Yanjie Pu; Jin Huang; Jinyu Yu (Bulletin of Environmental Contamination and Toxicology, 2020)

Fluoride-Induced Alteration in the Diversity and Composition of Bacterial Microbiota in Mice Colon - Rong Fu; Ruiyan Niu; Rui Li; Baijuan Yue; Xuhua Zhang; Qiqi Cao; Jundong Wang; Zilong Sun (Biological Trace Element Research, 2020)

Habitat fragmentation changes top‐down and bottom‐up controls of food webs - Rong Wang; Xin Zhang; Yi‐Su Shi; Yuan‐Yuan Li; Jianguo Wu; Fangliang He; Xiao‐Yong Chen (Ecology, 2020)
Top‐down and bottom‐up controls regulate the structure and stability of ecosystems, but their relative roles in terrestrial systems have been debated. Here we studied a hydro‐inundated land‐bridge system in subtropical China and tested the relative importance of these two controls in determining the rodent‐mediated regeneration of a locally dominant tree species. Our results showed that both controls operated in terrestrial habitats and that their relative importance switched as habitat size changed. Habitat loss initially removed predators of rodents that released rodent populations and triggered massive seed predation (top‐down control), leading to reduced seedling establishment. A further reduction in habitat size led to decrease in rodent population that was supposed to increase seedling survival of the tree species, but the decline in habitat size deteriorated the abiotic environments (bottom‐up control) that severely prevented seedling recruitment. As the ongoing global land use change is creating increasing number of small‐sized forest fragments, our findings provide novel insights into the restoration of seriously fragmented forests.

A Novel Eyes Topical Drug Delivery System: CsA-LNC for the Treatment of DED - Anan Zhang; Rong Sun; Meixin Ran; Yaxin Deng; Ying Ge; Yunjing Zhu; Xiumei Tao; Lixia Shang; Jingxin Gou; Haibing He; Tian Yin; Yanjiao Wang; et al. (Pharmaceutical Research, 2020)

Genetic diversity analysis for narrow-leafed lupin (Lupinus angustifolius L.) by SSR markers - Yishan Ji; Rong Liu; Jinguo Hu; Yuning Huang; Dong Wang; Guan Li; Md. Mosiur Rahman; Hongyan Zhang; Chenyu Wang; Mengwei Li; Tao Yang; Xuxiao Zong (Molecular Biology Reports, 2020)

Identification of Ala2Thr mutation in insulin gene from a Chinese MODY10 family - Juan Zhang; Yanjun Liu; Ming Li; Xiaoxu Ge; Ying Wang; Xin Huang; Di Yang; Rong Zhang; Yating Chen; Ming Lu; Jun Yin; Mingqiang Song; et al. (Molecular and Cellular Biochemistry, 2020)

A review of progress in coupled ocean-atmosphere model developments for ENSO studies in China - Rong-Hua Zhang; Yongqiang Yu; Zhenya Song; Hong-Li Ren; Youmin Tang; Fangli Qiao; Tongwen Wu; Chuan Gao; Junya Hu; Feng Tian; Yuchao Zhu; Lin Chen; et al. (Journal of Oceanology and Limnology, 2020)

Farm animals and aquaculture: significant reservoirs of mobile colistin resistance genes - Yingbo Shen; Rong Zhang; Stefan Schwarz; Congming Wu; Jianzhong Shen; Timothy R. Walsh; Yang Wang (Environmental Microbiology, 2020)
Summary Colistin resistance has attracted substantial attention after colistin was considered as a last‐resort drug for the treatment of infections caused by carbapenem‐resistant and/or multidrug‐resistant (MDR) Gram‐negative bacteria in clinical settings. However, with the discovery of highly mobile colistin resistance ( mcr ) genes, colistin resistance has become an increasingly urgent issue worldwide. Despite many reviews, which summarized the prevalence, mechanisms, and structures of these genes in bacteria of human and animal origin, studies on the prevalence of mobile colistin resistance genes in aquaculture and their transmission between animals and humans remain scarce. Herein, we review recent reports on the prevalence of colistin resistance genes in animals, especially wildlife and aquaculture, and their possibility of transmission to humans via the food chain. This review also gives some insights into the routine surveillance, changing policy and replacement of polymyxins by polymyxin derivatives, molecular inhibitors, and traditional Chinese medicine to tackle colistin resistance.

Microalgae for saline wastewater treatment: a critical review - Hoang Nhat Phong Vo; Huu Hao Ngo; Wenshan Guo; Soon Woong Chang; Dinh Duc Nguyen; Zhuo Chen; Xiaochang C. Wang; Rong Chen; Xinbo Zhang (Critical Reviews in Environmental Science and Technology, 2020)

A study on the effects of salinity and pH on PSII function in mulberry seedling leaves under saline–alkali mixed stress - Zhang Huihui; Li Xin; Che Yan-hui; Wang Yue; Li Ma-bo; Yang Rong-yi; Xu Nan; Sun Guang-yu (Trees, 2020)

Effect of expanded shrub litter on decomposition of graminoid litter in a temperate freshwater marsh - Xinhou Zhang; Yiping Wang; Wei Jiang; Rong Mao (Plant and Soil, 2020)

Synthesis, pharmacological evaluation and molecular docking of novel R-/S-2-(2-hydroxypropanamido)-5-trifluoromethyl benzoic acid as dual anti-inflammatory anti-platelet aggregation agents - Rong Rong; Rui-zhen Zhang; Xin Wang; Yu-han Dan; Yun-li Zhao; Zhi-guo Yu (Naunyn-Schmiedeberg's Archives of Pharmacology, 2020)

The isolation and culture of giant panda (Ailuropoda melanoleuca) breast milk cells - Chen Yijiao; Wang Donghui; Liu Yuliang; Li Feiping; He Ping; Cai Zhigang; Zhang Hao; Chen Min; Hou Rong; An Junhui (In Vitro Cellular & Developmental Biology - Animal, 2020)

Sugar transporter genes in grass carp (Ctenopharyngodon idellus): molecular cloning, characterization, and expression in response to different stocking densities - Xiao Liang; Fengying Yan; Yu Gao; Mei Xiong; Haishan Wang; Kommaly Onxayvieng; Rong Tang; Li Li; Xi Zhang; Wei Chi; Marina Piria; Mirna Mrkonjić Fuka; et al. (Fish Physiology and Biochemistry, 2020)

Effects of streptozotocin on pancreatic islet β-cell apoptosis and glucose metabolism in zebrafish larvae - Xue Wang; Xue-liang Yang; Ke-chun Liu; Wen-long Sheng; Qing Xia; Rong-chun Wang; Xi-qiang Chen; Yun Zhang (Fish Physiology and Biochemistry, 2020)

Central autonomic network functional connectivity: correlation with baroreflex function and cardiovascular variability in older adults - Kan Ding; Takashi Tarumi; Ciwen Wang; Steven Vernino; Rong Zhang; David C. Zhu (Brain Structure and Function, 2020)

Molecular evolution of GII.P17-GII.17 norovirus associated with sporadic acute gastroenteritis cases during 2013–2018 in Zhoushan Islands, China - Can Chen; Bing Wu; Hui Zhang; Ke-Feng Li; Rong Liu; Hong-Ling Wang; Jian-Bo Yan (Virus Genes, 2020)

Simulation of the landform change process on a purple soil slope due to tillage erosion and water erosion using UAV technology - Chao Yang; Zheng-an Su; Jian-rong Fan; Hai-dong Fang; Liang-tao Shi; Jian-hui Zhang; Zhou-yao He; Tao Zhou; Xiao-yi Wang (Journal of Mountain Science, 2020)

High resolution UPLC-MS/MS method for simultaneous separation and determination of six flavonoids from semen cuscutae extract in rat plasma: application to comparative pharmacokinetic studies in normal and kidney-deficient rats - Wei Zhang; Zhi-Tian Fu; Yao Xie; Zhi-Wen Duan; Yu Wang; Rong-Hua Fan (Natural Product Research, 2020)

Iridoid, phenylethanoid and flavonoid glycosides from Forsythia suspensa - Qian Wei; Rong Zhang; Qin Wang; Xin Jia Yan; Quan Wei Yu; Fu Xia Yan; Chang Li; Yue Hu Pei (Natural Product Research, 2020)

Transcript profiling of genes involved in carotenoid biosynthesis among three carrot cultivars with various taproot colors - Ya-Hui Wang; Tong Li; Rong-Rong Zhang; Ahmed Khadr; Yong-Sheng Tian; Zhi-Sheng Xu; Ai-Sheng Xiong (Protoplasma, 2020)

Physiological and proteomic responses of mangrove plant Avicennia marina seedlings to simulated periodical inundation - Huan Li; Zan Li; Zhi-Jun Shen; Mei-Rong Luo; Yi-Ling Liu; Ming-Yue Wei; Wen-Hua Wang; Ying-Ying Qin; Chang-Hao Gao; Ke-Ke Li; Qian-Su Ding; Shan Zhang; et al. (Plant and Soil, 2020)

Representing surface wind stress response to mesoscale SST perturbations in western coast of South America using Tikhonov regularization method - Chaoran Cui; Rong-Hua Zhang; Hongna Wang; Yanzhou Wei (Journal of Oceanology and Limnology, 2020)

MiR-145 alleviates Hcy-induced VSMC proliferation, migration, and phenotypic switch through repression of the PI3K/Akt/mTOR pathway - Minghao Zhang; Fan Li; Xiuyu Wang; Jian Gong; Yushan Xian; Guan Wang; Zihan Zheng; Chenxu Shang; Bo Wang; Yanhao He; Weirong Wang; Rong Lin (Histochemistry and Cell Biology, 2020)

The Diversity of Associated Microorganisms in Different Organs and Rhizospheric Soil of Arctium lappa L. - Yanping Xing; Yanyun Yang; Liang Xu; Ning Hao; Rong Zhao; Jiahao Wang; Shengnan Li; Dachuan Zhang; Tingting Zhang; Tingguo Kang (Current Microbiology, 2020)

The effects of mesoscale oceanographic structures and ambient conditions on the catch of albacore tuna in the South Pacific longline fishery - Cheng Zhou; Pingguo He; Liuxiong Xu; Pascal Bach; Xuefang Wang; Rong Wan; Hao Tang; Yu Zhang (Fisheries Oceanography, 2020)
Albacore tuna ( Thunnus alalunga ) exhibit patchy concentrations associated with biological process at a wide range of spatial scales, resulting in variations in their catchability by fishing gears. Here, we investigated the association of catch variation for pelagic longlines in the South Pacific Ocean with oceanographic mesoscale structures (in horizontal dimension) and ambient conditions (in vertical dimension). The distribution of albacore tuna as indicated by catch per unit effort (CPUE) of longlines was significantly related to the presence of mesoscale structures, with higher CPUE found at locations closer to thermal fronts and with greater gradient magnitudes, as well as areas marked by peripheral contour line of the anticyclone indicated by Sea Surface Height Anomalies ~0.05 m. Surface mesoscale current velocity had the negative effect on the catch, probably as a result of decreased catchability by shoaling the hook depth. Vertical distribution of albacore in the survey region of South Pacific Ocean was hardly restricted by ambient temperature and oxygen concentration, though effect of ambient temperature was relevant and showed a negatively linear correlation with CPUE at the range of 20–24°C. On the contrary, albacore distribution was evidently dominated by the water depth and showed strong preference on water depth of 200 m, which was likely a representative feeding layer. The presence of prey resources and their accessibility by albacore revealed by mesoscale structures in the biological and physical processes, and catchability determined by the location of the baited hooks comprehensively contribute to the variability of catch.

Toonapolyynes A–D, new polyynes from Toona ciliata - Rong Wang; Fu-Qiang Ni; Jun Sang; Yao Zhang; Jia-Luo Huang; Sheng Yin; Gui-Hua Tang (Natural Product Research, 2020)

Simulating Spatial Variation of Soil Carbon Content in the Yellow River Delta: Comparative Analysis of Two Artificial Neural Network Models - Chen Wang; Yuan Cui; Ziwen Ma; Yutong Guo; Qian Wang; Yujiao Xiu; Rong Xiao; Mingxiang Zhang (Wetlands, 2020)

Reduced mineral fertilization coupled with straw return in field mesocosm vegetable cultivation helps to coordinate greenhouse gas emissions and vegetable production - Rong Huang; Jiang Liu; Xinhua He; Deti Xie; Jiupai Ni; Chang Xu; Yarong Zhang; En Ci; Zifang Wang; Ming Gao (Journal of Soils and Sediments, 2020)

Cell membrane damage induced by continuous stress of artemisinin sustained-release microspheres (ASMs) on Microcystis aeruginosa at different physiological stages - Lixiao Ni; Feifei Yue; Jianhua Zhang; Shiyi Rong; Xuanyu Liu; Yifei Wang; Peifang Wang; Danye Li; Na Wang; Hanqi Wu; Shiyin Li (Environmental Science and Pollution Research, 2020)

Atorvastatin ameliorates depressive behaviors and neuroinflammatory in streptozotocin-induced diabetic mice - Zhang Hai-Na; Yu Xu-Ben; Tang Cong-Rong; Cao Yan-Cheng; Yang Fan; Xu Lei-Mei; Sun Ruo-Lan; Ye-Zi; Wang Ye-Xuan; Liang Jing (Psychopharmacology, 2020)

Effect of different seasons (spring vs summer) on the microbiota diversity in the feces of dairy cows - Han Li; Rong Li; Huijun Chen; Jing Gao; Yu Wang; Yifeng Zhang; Zhili Qi (International Journal of Biometeorology, 2020)

Steroidogenic acute regulatory protein/aldosterone synthase mediates angiotensin II-induced cardiac fibrosis and hypertrophy - Wei-Wei Zhang; Rong-Hua Zheng; Feng Bai; Katelyn Sturdivant; Ning-Ping Wang; Erskine A. James; Himangshu S. Bose; Zhi-Qing Zhao (Molecular Biology Reports, 2020)

Utilization of pre-existing competent and barren quartz veins as hosts to later orogenic gold ores at Huangjindong gold deposit, Jiangnan Orogen, southern China - Liang Zhang; David I. Groves; Li-Qiang Yang; Si-Chen Sun; Roberto F. Weinberg; Jiu-Yi Wang; Sheng-Gang Wu; Lei Gao; Lan-Ling Yuan; Rong-Hua Li (Mineralium Deposita, 2020)

Analysis of nicotine-induced metabolic changes in Blakeslea trispora by GC-MS - Yang Liu; You-ran Shao; Xiang-yu Li; Zhi-ming Wang; Li-rong Yang; Yu-zhou Zhang; Mian-bin Wu; Jian-ming Yao (Journal of Zhejiang University-SCIENCE B, 2020)

Developing stripe rust resistant wheat (Triticum aestivum L.) lines with gene pyramiding strategy and marker-assisted selection - Rong Liu; Jing Lu; Min Zhou; Shigang Zheng; Zehou Liu; Chihong Zhang; Mei Du; Minxiu Wang; Yunfang Li; Yu Wu; Lei Zhang (Genetic Resources and Crop Evolution, 2020)

Development of Climate and Earth System Models in China: Past Achievements and New CMIP6 Results - Tianjun Zhou; Ziming Chen; Liwei Zou; Xiaolong Chen; Yongqiang Yu; Bin Wang; Qing Bao; Ying Bao; Jian Cao; Bian He; Shuai Hu; Lijuan Li; et al. (Journal of Meteorological Research, 2020)

Stable Isotope Signatures and Moisture Transport of a Typical Heavy Precipitation Case in the Southern Tianshan Mountains - Liwei Wang; Mingjun Zhang; Shengjie Wang; Athanassios A. Argiriou; Gaofei Wang; Vasileios Salamalikis; Mengyu Shi; Rong Jiao (Chinese Geographical Science, 2020)

Sky islands as foci for divergence of fig trees and their pollinators in southwest China - Jun‐Yin Deng; Rong‐Hua Fu; Stephen G. Compton; Mei Liu; Qin Wang; Chuan Yuan; Lu‐Shui Zhang; Yan Chen (Molecular Ecology, 2020)
The dynamics of populations and their divergence over time have shaped current levels of biodiversity and in the case of the “sky islands” of mountainous southwest (SW) China have resulted in an area of exceptional botanical diversity. Ficus tikoua is a prostrate fig tree subendemic to the area that displays unique intraspecific diversity, producing figs typical of different pollination modes in different parts of its range. By combining climate models, genetic variation in populations of the tree's obligate fig wasp pollinators and distributions of the different plant phenotypes, we examined how this unusual situation may have developed. We identified three genetically distinct groups of a single Ceratosolen pollinator species that have largely parapatric distributions. The complex topography of the region contributed to genetic divergence among the pollinators by facilitating geographical isolation and providing refugia. Migration along elevations in response to climate oscillations further enhanced genetic differentiation of the three pollinator groups. Their distributions loosely correspond to the distributions of the functionally significant morphological differences in the male figs of their host plants, but postglacial expansion of one group has not been matched by spread of its associated plant phenotype, possibly due to a major river barrier. The results highlight how interplay between the complex topography of the “sky island” complex and climate change has shaped intraspecies differentiation and relationships between the plant and its pollinator. Similar processes may explain the exceptional botanical diversity of SW China.

Effects of shallow groundwater table fluctuations on nitrogen in the groundwater and soil profile in the nearshore vegetable fields of Erhai Lake, southwest China - Dan Zhang; Maopan Fan; Hongbin Liu; Rong Wang; Jixia Zhao; Yanxian Yang; Rongyang Cui; Anqiang Chen (Journal of Soils and Sediments, 2020)

Prenatal exposure to organophosphate pesticides, maternal paraoxonase 1 genotype, and childhood neurodevelopment at 24 months of age in Shandong, China - Yiwen Wang; Yan Zhang; Lin Ji; Yijun Zhou; Rong Shi; Michihiro Kamijima; Jun Ueyama; Yu Gao; Ying Tian (Environmental Science and Pollution Research, 2020)

Antler stem cells as a novel stem cell source for reducing liver fibrosis - Xiaoli Rong; Yanyan Yang; Guokun Zhang; Haiying Zhang; Chunyi Li; Yimin Wang (Cell and Tissue Research, 2020)
Liver fibrosis results from collagen fiber deposition. Antler stem cells (ASCs) naturally in vivo differentiate into cartilage, which is only made of Col II in collagen component; whereas liver fibrosis is caused by over-abundance of Col I and III. In addition, ASCs can effectively promote regenerative wound healing in which tissue contains very few collagen fibers (Col I). In this study, we investigate the therapeutic effects of ASCs in a rat model of CCl 4 -induced liver fibrosis. Rats were treated with ASCs for 4 weeks in vivo, then biochemical and histopathological analyses were performed. Furthermore, we established cell co-culture systems of hepatic stellate cells (HSCs) and ASCs and of M1 macrophages and ASCs in vitro. Mesenchymal stem cells (MSCs) were used as a positive control. The results showed that ASC transplantation alleviated liver fibrosis effectively as evidenced by reduced collagen accumulation, decreased fatty degeneration, increased hepatocyte regeneration, decreased inflammation and significantly enhanced liver function; moreover, ASCs decreased the expression of pro-fibrogenic factors including TGF-β and α-SMA. Additionally, our study showed that ASCs inhibit HSC activation and proliferation by controlling the expression of MMPs, TIMP1, TGF-β, α-SMA and COL1A2 involved in these processes. Our results suggested that ASCs alleviate liver fibrosis effectively and inhibit HSC activation. Thus, ASCs may serve as a novel stem cell source for the treatment of liver fibrosis in the clinic.

Preparation and In vitro Evaluation of FDM 3D-Printed Ellipsoid-Shaped Gastric Floating Tablets with Low Infill Percentages - Di Chen; Xiang-Yu Xu; Rui Li; Gen-Ao Zang; Yue Zhang; Ming-Rui Wang; Meng-Fei Xiong; Jia-Rui Xu; Ting Wang; Hui Fu; Qin Hu; Bin Wu; et al. (AAPS PharmSciTech, 2020)

One bis-indole alkaloid-voacamine from Voacanga africana Stapf: biological activity evaluation of PTP1B in vitro utilizing enzymology method based on SPRi expriment - Yan-Qiu Wang; Hong-Xiang Li; Xiao-Chun Liu; Jin-Shuang Zhao; Rong-Qiang Liu; Wen-ying Huai; Wei-Jun Ding; Tian-E Zhang; Yun Deng (Natural Product Research, 2019)

Zizania aquatica–duck ecosystem with recycled biogas slurry maintained crop yield - Guiliang Wang; Jianghong Zhang; Xiangming Kou; Shouhong Wang; Jianfeng Liu; Rong Xu; Guangming Han; Leiming Wu; Lingyu Zhu (Nutrient Cycling in Agroecosystems, 2019)

Effects of Different Preservation Methods on Physicochemical Property of Marine Pathogen Vibrio anguillarum - Yongxiang Yu; Zheng Zhang; Yingeng Wang; Meijie Liao; Xiaojun Rong; Bin Li; Hao Zhang (Journal of Ocean University of China, 2019)

Interaction Between Planetary Boundary Layer and PM2.5 Pollution in Megacities in China: a Review - Yucong Miao; Jing Li; Shiguang Miao; Huizheng Che; Yaqiang Wang; Xiaoye Zhang; Rong Zhu; Shuhua Liu (Current Pollution Reports, 2019)
Purpose of Review During the past decades, the number and size of megacities have been growing dramatically in China. Most of Chinese megacities are suffering from heavy PM 2.5 pollution. In the pollution formation, the planetary boundary layer (PBL) plays an important role. This review is aimed at presenting the current state of understanding of the PBL-PM 2.5 interaction in megacities, as well as to identify the main gaps in current knowledge and further research needs. Recent Findings The PBL is critical to the formation of urban PM 2.5 pollution at multiple temporal scales, ranging from diurnal change to seasonal variation. For the essential PBL structure/process in pollution, the coastal megacities have different concerns from the mountainous or land-locked megacities. In the coastal cities, the recirculation induced by sea-land breeze can accumulate pollutants, whereas in the valley/basin, the blocking effects of terrains can lead to stagnant conditions and thermal inversion. Within a megacity, although the urbanization-induced land use change can cause thermodynamic perturbations and facilitate the development of PBL, the increases in emissions outweigh this impact, resulting in a net increase of aerosol concentration. Moreover, the aerosol radiative effects can modify the PBL by heating the upper layers and reducing the surface heat flux, suppressing the PBL and exacerbating the pollution. Summary This review presented the PBL-PM 2.5 interaction in 13 Chinese megacities with various geographic conditions and elucidated the critical influencing processes. To further understand the complicated interactions, long-term observations of meteorology and aerosol properties with multi-layers in the PBL need to be implemented.

Impact of CYP2R1, CYP27A1 and CYP27B1 genetic polymorphisms controlling vitamin D metabolism on susceptibility to hepatitis C virus infection in a high-risk Chinese population - Jing-jing Yang; Hao-zhi Fan; Ting Tian; Meng-ping Wu; Chao-nan Xie; Peng Huang; Rong-bin Yu; Hong-Gang Yi; Yun Zhang; Jie Wang (Archives of Virology, 2019)

Root diversity in sesame (Sesamum indicum L.): insights into the morphological, anatomical and gene expression profiles - Ruqi Su; Rong Zhou; Marie Ali Mmadi; Donghua Li; Lu Qin; Aili Liu; Jianqiang Wang; Yuan Gao; Mengyuan Wei; Lisong Shi; Ziming Wu; Jun You; et al. (Planta, 2019)

Synergistic effects of stromal cell-derived factor-1α and bone morphogenetic protein-2 treatment on odontogenic differentiation of human stem cells from apical papilla cultured in the VitroGel 3D system - Min Xiao; Jun Qiu; Rong Kuang; Beidi Zhang; Wei Wang; Qing Yu (Cell and Tissue Research, 2019)

Urinary Metal Concentrations and the Incidence of Hypertension Among Adult Residents Along the Yangtze River, China - Qi Zhong; Chun-xiao Jiang; Chi Zhang; Qian Zhang; Qi-rong Qin; Xiao-dong Wang; Fen Huang (Archives of Environmental Contamination and Toxicology, 2019)

Network parameters quantify loss of assemblage structure in human‐impacted lake ecosystems - Rong Wang; John A. Dearing; C. Patrick Doncaster; Xiangdong Yang; Enlou Zhang; Peter G. Langdon; Hui Yang; Xuhui Dong; Zhujun Hu; Min Xu; Yanjie Zhao; Ji Shen (Global Change Biology, 2019)
Lake biodiversity is an incomplete indicator of exogenous forcing insofar as it ignores underlying deformations of community structure. Here, we seek a proxy for deformation in a network of diatom assemblages comprising 452 species in 273 lakes across China. We test predictions from network theory that nodes of similar type will tend to self‐organize in an unstressed system to a positively skewed frequency distribution of nodal degree. The empirical data reveal shifts in the frequency distributions of species associations across regions, from positive skew in lakes in west China with a history of low human impacts, to predominantly negative skew amongst lakes in highly disturbed regions in east China. Skew values relate strongly to nutrient loading from agricultural activity and urbanization, as measured by total phosphorus in lake water. Reconstructions through time show that positive skew reduces with temporal intensification of human impacts in the lake and surrounding catchments, and rises as lakes recover from disturbance. Our study illustrates how network parameters can track the loss of aquatic assemblage structure in lakes associated with human pressures.

Identification and Phylogenetic Analysis of Xanthomonas albilineans (Ashby) Dowson Based on Multiple Gene Sequences in Yunnan Province, China - Rong-Yue Zhang; Xiao-Yan Wang; Hong-Li Shan; Jie Li; Wen-Feng Li; Xiao-Yan Cang; Zhi-Ming Luo; Jiong Yin; Ying-Kun Huang (Sugar Tech, 2019)

Molecular Identification of Sugarcane White Leaf in Puer, Yunnan Province, China - Rong-Yue Zhang; Wen-Feng Li; Ying-Kun Huang; Xiao-Yan Wang; Hong-Li Shan; Jie Li; Xiao-Yan Cang; Zhi-Ming Luo; Jiong Yin (Sugar Tech, 2019)

Genetic dissection of stalk lodging-related traits using an IBM Syn10 DH population in maize across three environments (Zea mays L.) - Yanling Zhang; Tianhu Liang; Min Chen; Yinchao Zhang; Tao Wang; Haijian Lin; Tingzhao Rong; Chaoying Zou; Peng Liu; Michael Lee; Guangtang Pan; Yaou Shen; et al. (Molecular Genetics and Genomics, 2019)

Uranium sorption onto mullite: Characteristics of isotherms, kinetics and thermodynamics - Liao Rong; Shi Zeming; Hou Yun; Zhang Kailiang; Zhang Junji; Wang Xinyu; Cheng Ke; Yang Lvhang (Journal of Earth System Science, 2019)

Developing genetically segregating populations for localization of novel sugarcane brown rust resistance genes - Xiao-Yan Wang; Wen-Feng Li; Ying-Kun Huang; Hong-Li Shan; Rong-Yue Zhang; Jie Li; Xiao-Yan Cang; Zhi-Ming Luo; Jiong Yin (Euphytica, 2019)

Factors affecting interdecadal variability of air–sea CO2 fluxes in the tropical Pacific, revealed by an ocean physical–biogeochemical model - Feng Tian; Rong-Hua Zhang; Xiujun Wang (Climate Dynamics, 2019)

Trends of sea surface wind energy over the South China Sea - Bo Jiang; Yongliang Wei; Jie Ding; Rong Zhang; Yuxin Liu; Xiaoyong Wang; Yizhou Fang (Journal of Oceanology and Limnology, 2019)

A molecular survey of Anaplasma, Ehrlichia, Bartonella and Theileria in ticks collected from southeastern China - Juan Hou; Feng Ling; Ying Liu; Rong Zhang; Xiuping Song; Ruting Huang; Yuyan Wu; Jinna Wang; Jimin Sun; Zhenyu Gong (Experimental and Applied Acarology, 2019)

Identification of cis-regulatory regions responsible for developmental and hormonal regulation of HbHMGS1 in transgenic Arabidopsis thaliana - Xiao-Xiao Gong; Bing-Yu Yan; Yu-Rong Tan; Xuan Gao; Dan Wang; Heng Zhang; Peng Wang; Shuang-Jiang Li; Yi Wang; Lu-Yao Zhou; Jin-Ping Liu (Biotechnology Letters, 2019)

Molecular cloning and functional characterization of a seed-specific VvβVPE gene promoter from Vitis vinifera - Peijie Gong; Rong Wei; Yan Li; Ruipu Wang; Yujin Tang; Ling Wang; Huijun Zhu; Yuejin Wang; Chaohong Zhang (Planta, 2019)

Effect of Apolipoprotein E Genotypes on Huntington’s Disease Phenotypes in a Han Chinese Population - Xiao-Yan Li; Yan-Bin Zhang; Miao Xu; Hong-Rong Cheng; Yi Dong; Wang Ni; Hong-Lei Li; Zhi-Ying Wu (Neuroscience Bulletin, 2019)

Cloud Radiative Feedbacks during the ENSO Cycle Simulated by CAMS-CSM - Lin Chen; Lijuan Hua; Xinyao Rong; Jian Li; Lu Wang; Guo Zhang; Ming Sun; Zi’an Ge (Journal of Meteorological Research, 2019)

Fast and non–derivative method based on high–performance liquid chromatography–charged aerosol detection for the determination of fatty acids from Agastache rugosa (Fisch. et Mey.) O. Ktze. seeds - Rong Yang; Zhuona Wu; Yiqiong Pu; Tong Zhang; Bing Wang (Natural Product Research, 2019)

Species with moderate intraspecific trait variability are locally abundant within an environmentally heterogeneous subtropical forest - Guochun Shen; En-Rong Yan; Avi Bar-Massada; Jian Zhang; Heming Liu; Xihua Wang; Mingshan Xu (Oecologia, 2019)

Relationship between genetic variation in the α2A-adrenergic receptor and the cardiovascular effects of dexmedetomidine in the Chinese Han population - Shao-jun Zhu; Kui-rong Wang; Xiong-xin Zhang; Sheng-mei Zhu (Journal of Zhejiang University-SCIENCE B, 2019)

Influences of immersion bathing in Bacillus velezensis DY-6 on growth performance, non-specific immune enzyme activities and gut microbiota of Apostichopus japonicus - Jinyan Wang; Bin Li; Yingeng Wang; Meijie Liao; Xiaojun Rong; Zheng Zhang (Journal of Oceanology and Limnology, 2019)

Arbuscular mycorrhizal fungi abundance was sensitive to nitrogen addition but diversity was sensitive to phosphorus addition in karst ecosystems - Dan Xiao; Rongxiao Che; Xin Liu; Yongjun Tan; Rong Yang; Wei Zhang; Xunyang He; Zhihong Xu; Kelin Wang (Biology and Fertility of Soils, 2019)

HL2 on chromosome 7D of wheat (Triticum aestivum L.) regulates both head length and spikelet number - Hongni Yao; Quan Xie; Shulin Xue; Jing Luo; Jikang Lu; Zhongxin Kong; Yongpan Wang; Wenling Zhai; Nan Lu; Rong Wei; Yang Yang; Yuzhou Han; et al. (Theoretical and Applied Genetics, 2019)

Identification and Evaluation of Resistance to Sugarcane Streak Mosaic Virus (SCSMV) and Sorghum Mosaic Virus (SrMV) in Excellent Sugarcane Innovation Germplasms in China - Wen-Feng Li; Hong-Li Shan; Xiao-Yan Cang; Xin Lu; Rong-Yue Zhang; Xiao-Yan Wang; Jiong Yin; Zhi-Ming Luo; Ying-Kun Huang (Sugar Tech, 2019)

Field Resistance of Different Sugarcane Varieties to Sugarcane Thrips (Fulmekiola serratus) in China - Zhi-Ming Luo; Xiao-Yan Wang; Ying-Kun Huang; Rong-Yue Zhang; Wen-Feng Li; Hong-Li Shan; Xiao-Yan Cang; Jie Li; Jiong Yin (Sugar Tech, 2019)

Hydrocarbon generation characteristics and exploration prospects of Proterozoic source rocks in China - Wenzhi Zhao; Xiaomei Wang; Suyun Hu; Shuichang Zhang; Huajian Wang; Shuwei Guan; Yuntao Ye; Rong Ren; Tongshan Wang (Science China Earth Sciences, 2019)

Effects of different substrates on nitrogen and phosphorus removal in horizontal subsurface flow constructed wetlands - Rui Xu; Yong Zhang; Rong Liu; Yun Cao; Guoxiang Wang; Lingchen Ji; Yifan Xu (Environmental Science and Pollution Research, 2019)

Calcium intake and colon cancer risk subtypes by tumor molecular characteristics - NaNa Keum; Li Liu; Tsuyoshi Hamada; Zhi Rong Qian; Jonathan A. Nowak; Yin Cao; Annacarolina da Silva; Keisuke Kosumi; Mingyang Song; Daniel Nevo; Molin Wang; Andrew T. Chan; et al. (Cancer Causes & Control, 2019)

Comprehensive meta-analysis and co-expression network analysis identify candidate genes for salt stress response in Arabidopsis - Luoyan Zhang; Zhen Zhang; Xuejie Zhang; Yan Yao; Rong Wang; Benyao Duan; Shoujin Fan (Plant Biosystems, 2019)

Interleukin-26 upregulates interleukin-22 production by human CD4+ T cells in tuberculous pleurisy - Min Zhang; Yi-Ran Niu; Jing-Yuan Liu; Xiao-Shan Wei; Xiao-Rong Wang; Lin-Lin Ye; Wen-Bei Peng; Jian-Chu Zhang; Xiao-Nan Tao; Qiong Zhou (Journal of Molecular Medicine, 2019)

First report of isolation and complete genome of Vibrio rotiferianus strain SSVR1601 from cage‐cultured black rockfish ( Sebastes schlegelii ) associated with skin ulcer - Zheng Zhang; Yong‐xiang Yu; Yong Jiang; Yin‐geng Wang; Mei‐jie Liao; Xiao‐jun Rong; Kai Wang; Hao Zhang; Jing Chen (Journal of Fish Diseases, 2019)
Vibrio rotiferianus is an important marine pathogen of various aquatic organisms and can be found widely distributed in the marine environment. To further characterize this pathogen, the pathogenic properties and genome of V. rotiferianus SSVR1601 isolated from Sebastes schlegelii with skin ulcer were analysed. SSVR1601 was shown to be short rod‐shaped cell with a single polar flagellum. Different degrees of pathological changes in fish kidney, intestine, gills and liver were observed after SSVR1601 challenge. The SSVR1601 genome consists of two chromosomes and two plasmids with a total of 5,717,113 bp, 42.04%–44.93% GC content, 5,269 predicted CDSs, 134 tRNAs and 40 rRNAs. The common virulence factors including OMPs, haemolysin, flagellin, DNase, entF , algU , tcpI , acfB and rfaD were found in strain SSVR1601. Furthermore, factors responsible for iron uptake ( fur , fepC and ccmC ) and types II, IV and VI secretion systems were detected, which are likely responsible for the pathogenicity of SSVR1601. The antimicrobial resistance genes, bacA , tet34 and norM, were detected based on Antibiotic Resistance Genes Database. The phylogenetic analysis revealed SSVR1601 to be most closely related to V. rotiferianus strains CAIM577 and B64D1.

Chronic stress impairs the aquaporin-4-mediated glymphatic transport through glucocorticoid signaling - Fang Wei; Jian Song; Cui Zhang; Jun Lin; Rong Xue; Li-Dong Shan; Shan Gong; Guo-Xing Zhang; Zheng-Hong Qin; Guang-Yin Xu; Lin-Hui Wang (Psychopharmacology, 2019)

MEG3 modulates TIGIT expression and CD4 + T cell activation through absorbing miR-23a - Jianhong Wang; Xiangxiang Liu; Caixia Hao; Yingjuan Lu; Xiaohui Duan; Rong Liang; Guangxun Gao; Tao Zhang (Molecular and Cellular Biochemistry, 2019)

A study of the characteristics of energy flux and its relationship with the summer monsoon over alpine wetlands in the source region of the Yellow River - Dongyu Jia; Jun Wen; Yaoming Ma; Juan Zhou; Jinlei Chen; Rong Liu; Xin Wang; Tangtang Zhang; Xin Lai; ZuoLiang Wang (Meteorology and Atmospheric Physics, 2019)

Changes in air temperature over China in response to the recent global warming hiatus - Qinqin Du; Mingjun Zhang; Shengjie Wang; Cunwei Che; Rong Ma; Zhuanzhuan Ma (Journal of Geographical Sciences, 2019)

A B-box zinc finger protein, MdBBX10, enhanced salt and drought stresses tolerance in Arabidopsis - Xin Liu; Rong Li; Yaqing Dai; Li Yuan; Qinghua Sun; Shizhong Zhang; Xiaoyun Wang (Plant Molecular Biology, 2019)

Mesoscale SST perturbation-induced impacts on climatological precipitation in the Kuroshio-Oyashio extension region, as revealed by the WRF simulations - Jiaxiang Gao; Rong-Hua Zhang; Hongna Wang (Journal of Oceanology and Limnology, 2019)

Relationship between polymorphisms of the lipid metabolism-related gene PLA2G16 and risk of colorectal cancer in the Chinese population - Xiao-Nv Xie; Jing Yu; Li-Hua Zhang; Zhi-Ying Luo; Dong-Sheng Ouyang; Ling-Jie Zheng; Chun-Yang Wang; Li Yang; Ling Chen; Zhi-Rong Tan (Functional & Integrative Genomics, 2019)

A CkDREB1 gene isolated from Caragana korshinskii Kom. enhances Arabidopsis drought and cold tolerance - Ziyi Zhang; Qi Yang; Chunlin Zhang; Lili Wei; Rong Yue; Guojing Li; Xiaofei Lin; Ruigang Wang (Brazilian Journal of Botany, 2019)

Underestimated ecosystem carbon turnover time and sequestration under the steady state assumption: A perspective from long‐term data assimilation - Rong Ge; Honglin He; Xiaoli Ren; Li Zhang; Guirui Yu; T. Luke Smallman; Tao Zhou; Shi‐Yong Yu; Yiqi Luo; Zongqiang Xie; Silong Wang; Huimin Wang; et al. (Global Change Biology, 2019)
It is critical to accurately estimate carbon (C) turnover time as it dominates the uncertainty in ecosystem C sinks and their response to future climate change. In the absence of direct observations of ecosystem C losses, C turnover times are commonly estimated under the steady state assumption ( SSA ), which has been applied across a large range of temporal and spatial scales including many at which the validity of the assumption is likely to be violated. However, the errors associated with improperly applying SSA to estimate C turnover time and its covariance with climate as well as ecosystem C sequestrations have yet to be fully quantified. Here, we developed a novel model‐data fusion framework and systematically analyzed the SSA ‐induced biases using time‐series data collected from 10 permanent forest plots in the eastern China monsoon region. The results showed that (a) the SSA significantly underestimated mean turnover times ( MTT s) by 29%, thereby leading to a 4.83‐fold underestimation of the net ecosystem productivity ( NEP ) in these forest ecosystems, a major C sink globally; (b) the SSA ‐induced bias in MTT and NEP correlates negatively with forest age, which provides a significant caveat for applying the SSA to young‐aged ecosystems; and (c) the sensitivity of MTT to temperature and precipitation was 22% and 42% lower, respectively, under the SSA . Thus, under the expected climate change, spatiotemporal changes in MTT are likely to be underestimated, thereby resulting in large errors in the variability of predicted global NEP . With the development of observation technology and the accumulation of spatiotemporal data, we suggest estimating MTT s at the disequilibrium state via long‐term data assimilation, thereby effectively reducing the uncertainty in ecosystem C sequestration estimations and providing a better understanding of regional or global C cycle dynamics and C‐climate feedback.

Genome-wide detection of additional fetal chromosomal abnormalities by cell-free DNA testing of 15,626 consecutive pregnant women - Hong Yao; Ya Gao; Jia Zhao; Rong Zhang; Huixin Xu; Huamei Hu; Yanmei Luo; Yuying Yuan; Meili Fu; Hongyun Zhang; Hui Jiang; Wei Wang; et al. (Science China Life Sciences, 2019)

An Assessment of ENSO Stability in CAMS Climate System Model Simulations - Lijuan Hua; Lin Chen; Xinyao Rong; Jian Li; Guo Zhang; Lu Wang (Journal of Meteorological Research, 2019)

Relations of Uranium Enrichment and Carbonaceous Debris within the Daying Uranium Deposit, Northern Ordos Basin - Fan Zhang; Yangquan Jiao; Liqun Wu; Hui Rong; Longhui Wang (Journal of Earth Science, 2019)

Angiogenesis in pancreatic cancer: current research status and clinical implications - Shuo Li; Hua-Xiang Xu; Chun-Tao Wu; Wen-Quan Wang; Wei Jin; He-Li Gao; Hao Li; Shi-Rong Zhang; Jin-Zhi Xu; Zi-Hao Qi; Quan-Xing Ni; Xian-Jun Yu; et al. (Angiogenesis, 2019)

Heterologous overexpression of Lithospermum erythrorhizon LeERF-1 gene increases drought and pathogen resistance in Arabidopsis - Rong-Jun Fang; Ai-Qian Li; Ru-Nan Tian; Wen-Ju Zhang; Ai-Lan Zou; Feng-Yao Wu; Yong-Hui Liao; Xiao-Ming Wang; Yan-Jun Pang; Rong-Wu Yang; Gui-Hua Lu; Jin-Liang Qi; et al. (Acta Physiologiae Plantarum, 2019)

Establishment and application of distant hybridization technology in fish - Shi Wang; Chenchen Tang; Min Tao; Qinbo Qin; Chun Zhang; Kaikun Luo; Rurong Zhao; Jing Wang; Li Ren; Jun Xiao; Fangzhou Hu; Rong Zhou; et al. (Science China Life Sciences, 2019)

Silurian integrative stratigraphy and timescale of China - Jiayu Rong; Yi Wang; Renbin Zhan; Junxuan Fan; Bing Huang; Peng Tang; Yue Li; Xiaole Zhang; Rongchang Wu; Guangxu Wang; Xin Wei (Science China Earth Sciences, 2019)

The Role of miR-150 in Stress-Induced Anxiety-Like Behavior in Mice - Wen-Juan Zhang; Wen-Yu Cao; Yan-Qing Huang; Yan-Hui Cui; Bo-Xuan Tu; Lai-Fa Wang; Guang-Jing Zou; Yu Liu; Zhao-Lan Hu; Rong Hu; Chang-Qi Li; Xiao-Wei Xing; et al. (Neurotoxicity Research, 2019)