Strategies for Improving Healing of the Gastric Epithelium Using Oral Solid Dispersions Loaded with Pentacyclic Triterpene–Rich Centella Extract - Saowanee Wannasarit; Panupong Puttarak; Kanidta Kaewkroek; Ruedeekorn Wiwattanapatapee (AAPS PharmSciTech, 2019)

Preparation, Characterization, and Properties of Inclusion Complexes of Balofloxacin with Cyclodextrins - Xiuyun Ren; Hongyun Qian; Peixiao Tang; Yuling Tang; Yuanyuan Liu; Hongyu Pu; Man Zhang; Ludan Zhao; Hui Li (AAPS PharmSciTech, 2019)

Preparation and Comparison of Oral Bioavailability for Different Nano-formulations of Olaparib - Akshay D. Pathade; Nagavendra Kommineni; Upendra Bulbake; Mohit M. Thummar; Gananadhamu Samanthula; Wahid Khan (AAPS PharmSciTech, 2019)

Formulation and Characterization of Novel Dry Suspension and Dry Emulsion of 20(S)-Protopanaxadiol - Liying Zhang; Congcong Xu; Jingjing Mao; Weiwei Wang; Han Han; Yiqiong Pu; Tong Zhang (AAPS PharmSciTech, 2019)

Insight into the Dissolution Molecular Mechanism of Ternary Solid Dispersions by Combined Experiments and Molecular Simulations - Run Han; Tianhe Huang; Xinyang Liu; Xunqing Yin; Haifeng Li; Jiahong Lu; Yuanhui Ji; Huimin Sun; Defang Ouyang (AAPS PharmSciTech, 2019)

Anti-solvent Precipitation Method Coupled Electrospinning Process to Produce Poorly Water-Soluble Drug-Loaded Orodispersible Films - Qingchun Song; Xiong Guo; Yi Sun; Mingshi Yang (AAPS PharmSciTech, 2019)

Levofloxacin Hemihydrate In Situ Gelling Ophthalmic Solution: Formulation Optimization and In Vitro and In Vivo Evaluation - Hemant Bhalerao; K. B. Koteshwara; Sajeev Chandran (AAPS PharmSciTech, 2019)

Effect of Roughness on the Dispersion of Dry Powders for Inhalation: a Dynamic Visualization Perspective - Xiang Kou; Paul W. S. Heng; Lai Wah Chan; Steven T. Wereley; M. Teresa Carvajal (AAPS PharmSciTech, 2019)

E-Selectin-Binding Peptide–Modified Bovine Serum Albumin Nanoparticles for the Treatment of Acute Lung Injury - Yu Liu; Bowen Yang; Xuan Zhao; Mingrong Xi; Zongning Yin (AAPS PharmSciTech, 2019)

Monitoring Magnesium Stearate Blending in a V-Blender Through Passive Vibration Measurements - Austin Cameron; Lauren Briens (AAPS PharmSciTech, 2019)

Quantitative Structure–Property Relationship Approach in Formulation Development: an Overview - Ajit S. Kulkarni; Amit J. Kasabe; Manish S. Bhatia; Neela M. Bhatia; Vinod L. Gaikwad (AAPS PharmSciTech, 2019)

Advancements in Dissolution Testing of Oral and Non-oral Formulations - Sandra Klein (AAPS PharmSciTech, 2019)

Quality by Design Approach for the Development of Self-Emulsifying Systems for Oral Delivery of Febuxostat: Pharmacokinetic and Pharmacodynamic Evaluation - Nagarjun Rangaraj; Saurabh Shah; Maruthi A J; Sravanthi Reddy Pailla; Hanumanth Srikanth Cheruvu; Sujatha D; Sunitha Sampathi (AAPS PharmSciTech, 2019)

Evaluation of the Disintegration Action of Soy Polysaccharide by Image Analysis - Rana Amayreh; Lorina Bisharat; Marco Cespi; Giovanni Filippo Palimieri; Alberto Berardi (AAPS PharmSciTech, 2019)

Effects of Temperature and Humidity on the Skin Permeation of Hydrophilic and Hydrophobic Drugs - Hiroaki Iikura; Koji Uchida; Chie Ogawa-Fuse; Kotatsu Bito; Satoru Naitou; Masaru Hosokawa; Takashi Uchida; Tomohiko Sano; Hiroaki Todo; Kenji Sugibayashi (AAPS PharmSciTech, 2019)

Leveraging Lyophilization Modeling for Reliable Development, Scale-up and Technology Transfer - Deliang Zhou; Sherwin Shang; Ted Tharp; Feroz Jameel; Kushal Sinha; Nandkishor K. Nere (AAPS PharmSciTech, 2019)

Mixing Cell: a Device to Mimic Extent of Lubrication and Shear in Continuous Tubular Blenders - Sara Moghtadernejad; M. Sebastian Escotet-Espinoza; Zhanjie Liu; Elisabeth Schäfer; Fernando Muzzio (AAPS PharmSciTech, 2019)

Printing and Additive Manufacturing - Jukka Rantanen; Niklas Sandler (AAPS PharmSciTech, 2019)

3D-Printed Wearable Personalized Orthodontic Retainers for Sustained Release of Clonidine Hydrochloride - Heliu Jiang; Junhui Fu; Mingguang Li; Shanshan Wang; Bo Zhuang; Haiyan Sun; Cheng Ge; Bin Feng; Yiguang Jin (AAPS PharmSciTech, 2019)

Freeze-Dried Self-Nanoemulsifying Self-Nanosuspension (SNESNS): a New Approach for the Preparation of a Highly Drug-Loaded Dosage Form - Hala N. ElShagea; Nermeen A. ElKasabgy; Rania H. Fahmy; Emad B. Basalious (AAPS PharmSciTech, 2019)

Dissolvable Microneedle-Mediated Transcutaneous Delivery of Tetanus Toxoid Elicits Effective Immune Response - Srijanaki Paravastu Pattarabhiran; Anjana Saju; Kanchan Rajendra Sonawane; Raghuraman Manimaran; Shubhmita Bhatnagar; Girdhari Roy; Radha Balkrishna Kulkarni; Venkata Vamsi Krishna Venuganti (AAPS PharmSciTech, 2019)

Fabrication Strategies of Scaffolds for Delivering Active Ingredients for Tissue Engineering - Nermeen A. Elkasabgy; Azza A. Mahmoud (AAPS PharmSciTech, 2019)

Temozolomide Conjugated Carbon Quantum Dots Embedded in Core/Shell Nanofibers Prepared by Coaxial Electrospinning as an Implantable Delivery System for Cell Imaging and Sustained Drug Release - Mojtaba Shamsipour; Amir Mohammad Mansouri; Pouran Moradipour (AAPS PharmSciTech, 2019)

Eco-Friendly Tadalafil Surfactant-Free Dry Emulsion Tablets (SFDETs) Stabilized by In Situ Self-Assembled Aggregates of Natural Oil and Native Cyclodextrins - Shaimaa M. Badr-Eldin; Gihan S. Labib; Mona H. Aburahma (AAPS PharmSciTech, 2019)

Self-Assembling Topical Nanomicellar Formulation to Improve Curcumin Absorption Across Ocular Tissues - Meshal Alshamrani; Sadia Sikder; Fohona Coulibaly; Abhirup Mandal; Dhananjay Pal; Ashim K. Mitra (AAPS PharmSciTech, 2019)

Chitosan-Based Drug Delivery Systems for Optimization of Photodynamic Therapy: a Review - Giovana Maria Fioramonti Calixto; Sarah Raquel de Annunzio; Francesca Damiani Victorelli; Maria Lucia Frade; Paula Scanavez Ferreira; Marlus Chorilli; Carla Raquel Fontana (AAPS PharmSciTech, 2019)

An in vitro Assessment of Thermo-Reversible Gel Formulation Containing Sunitinib Nanoparticles for Neovascular Age-Related Macular Degeneration - Priyanka Bhatt; Priya Narvekar; Rohan Lalani; Mahavir Bhupal Chougule; Yashwant Pathak; Vijaykumar Sutariya (AAPS PharmSciTech, 2019)

Effect of Formulation Variables on the Nasal Permeability and Stability of Naloxone Intranasal Formulations - Hao-Jui Hsu; Yang Yang; Venkateswara Pavuluri; Ciby Abraham; Suresh Babu Naraharisetti; Muhammad Ashraf; Manar Al-Ghabeish (AAPS PharmSciTech, 2019)

Surface Wettability Modulated by Surfactant and Its Effects on the Drug Release and Absorption of Fenofibrate Solid Dispersions - Baixue Yang; Chen Wei; Feiyou Qian; Sanming Li (AAPS PharmSciTech, 2019)

Liqui-Pellet: the Emerging Next-Generation Oral Dosage Form Which Stems from Liquisolid Concept in Combination with Pelletization Technology - Matthew Lam; Taravat Ghafourian; Ali Nokhodchi (AAPS PharmSciTech, 2019)

Curcumin-Loaded Nanostructured Lipid Carrier Modified with Partially Hydrolyzed Ginsenoside - Karthikeyan Selvaraj; Bong-Kyu Yoo (AAPS PharmSciTech, 2019)

Quality-by-Design Approach for Biological API Encapsulation into Polymersomes Using “Off-the-Shelf” Materials: a Study on L-Asparaginase - Alexsandra Conceição Apolinário; Rafael Bertelli Ferraro; Camila Areias de Oliveira; Adalberto Pessoa Jr; Carlota de Oliveira Rangel-Yagui (AAPS PharmSciTech, 2019)

Pharmaceutical Topical Delivery of Poorly Soluble Polyphenols: Potential Role in Prevention and Treatment of Melanoma - Gayathri Heenatigala Palliyage; Somnath Singh; Charles R. Ashby; Amit K. Tiwari; Harsh Chauhan (AAPS PharmSciTech, 2019)

Dentifrice Based on Fluoride–Hydrotalcite Compounds: Characterization and Release Capacity Evaluation by Novel In Vitro Methods - Cinzia Pagano; Luana Perioli; Fabio Marmottini; Daniele Ramella; Maria Cristina Tiralti; Maurizio Ricci (AAPS PharmSciTech, 2019)

Estimation of Anti-inflammatory and Analgesic Effects of Topical NANOCEN (Nanoliposomal Arthrocen) on Mice - Ramin Goudarzi; Sima Amini; Ahmad Reza Dehpour; Alireza Partoazar (AAPS PharmSciTech, 2019)

Cascade Impactor Equivalence Testing: Comparison of the Performance of the Modified Chi-Square Ratio Statistic (mCSRS) with the Original CSRS and EMA’s Average Bioequivalence Approach - Abhinav Kurumaddali; David Christopher; Dennis Sandell; Helen Strickland; Beth Morgan; Juergen Bulitta; Christopher Wiggenhorn; Stephen Stein; Svetlana Lyapustina; Günther Hochhaus (AAPS PharmSciTech, 2019)

Highly Water-Soluble Methotrexate-Polyethyleneglycol-Rhodamine Prodrug Micelle for High Tumor Inhibition Activity - Xiao Duan; Xue Yang; Changfeng Li; Lihua Song (AAPS PharmSciTech, 2019)

Development and Qualification of a Scale-Down Mammalian Cell Culture Model and Application in Design Space Development by Definitive Screening Design - Lei Nie; Dong Gao; Haiyan Jiang; Jinxia Gou; Lei Li; Feng Hu; Tingting Guo; Haibin Wang; Haibin Qu (AAPS PharmSciTech, 2019)

The Pharmacokinetic Prediction of Cyclosporin A after Coadministration with Wuzhi Capsule - Jingjing Fan; Lu Chen; Xiaoqing Lu; Mengxue Li; Liqin Zhu (AAPS PharmSciTech, 2019)

Effects of β-Cyclodextrin and Hydroxypropyl-β-Cyclodextrin Inclusions on the Degradation of Magnolol by Intestinal Bacteria - Lan Tang; Zhuanfeng Zhu; Miao Xie; Lipeng Cao; Xiao Lan Yu; Ran Zhang; Zhimin Ou; Weiguang Shan; Zhenhai Zhang (AAPS PharmSciTech, 2019)

In silico Tools at Early Stage of Pharmaceutical Development: Data Needs and Software Capabilities - Juliet Obianuju Njoku; Daniela Amaral Silva; Dwaipayan Mukherjee; Gregory K. Webster; Raimar Löbenberg (AAPS PharmSciTech, 2019)

Pulmonary and Regional Deposition of Nebulized and Dry Powder Aerosols in Ferrets - Philip J. Kuehl; Ramesh Chand; Jacob D. McDonald; David L. Hava; Wesley H. DeHaan (AAPS PharmSciTech, 2019)

Alginate Microspheres Elicit Innate M1-Inflammatory Response in Macrophages Leading to Bacillary Killing - Kalpesh Vaghasiya; Aisha Eram; Ankur Sharma; Eupa Ray; Suneera Adlakha; Rahul Kumar Verma (AAPS PharmSciTech, 2019)

Combination of UVB Absorbing Titanium Dioxide and Quercetin Nanogel for Skin Cancer Chemoprevention - Arvind Bagde; Ketan Patel; Arindam Mondal; Shallu Kutlehria; Nusrat Chowdhury; Aragaw Gebeyehu; Nilkumar Patel; Nagi Kumar; Mandip Singh (AAPS PharmSciTech, 2019)

Budesonide-Loaded Eudragit S 100 Nanocapsules for the Treatment of Acetic Acid-Induced Colitis in Animal Model - Milad Reda Qelliny; Usama Farghaly Aly; Omar Helmy Elgarhy; Khaled Aly Khaled (AAPS PharmSciTech, 2019)

Novel Application of Hot Melt Extrusion for the Manufacturing of Vaginal Films Containing Microbicide Candidate Dapivirine - Galit Regev; Sravan Kumar Patel; Bernard J. Moncla; John Twist; Brid Devlin; Lisa C. Rohan (AAPS PharmSciTech, 2019)

Correction to: Quantification of Inkjet-Printed Pharmaceuticals on Porous Substrates Using Raman Spectroscopy and Near-Infrared Spectroscopy - Magnus Edinger; Laura-Diana Iftimi; Daniel Markl; Mohammed Al-Sharabi; Daniel Bar-Shalom; Jukka Rantanen; Natalja Genina (AAPS PharmSciTech, 2019)

Flexibility of 3D Extruded Printing for a Novel Controlled-Release Puerarin Gastric Floating Tablet: Design of Internal Structure - Pingfei Li; Shiming Zhang; Wenliang Sun; Mengsuo Cui; Haoyang Wen; Qijun Li; Weisan Pan; Xinggang Yang (AAPS PharmSciTech, 2019)

Overview of Brazilian Requirements for Therapeutic Equivalence of Orally Inhaled and Nasal Drug Products - Marcia Cavallin Silva; Helena Silveira Costa; Bruna Nardy Valadares; Leticia Grecchi; Lee Nagao; Gustavo Mendes Lima Santos (AAPS PharmSciTech, 2019)

Evaluation of Abuse-Deterrent Characteristics of Tablets Prepared via Hot-Melt Extrusion - Xiaoming Xu; Akhtar Siddiqui; Charudharshini Srinivasan; Adil Mohammad; Ziyaur Rahman; Maxwell Korang-Yeboah; Xin Feng; Mansoor Khan; Muhammad Ashraf (AAPS PharmSciTech, 2019)

Modification of Three-Phase Drug Release Mode of Octreotide PLGA Microspheres by Microsphere-Gel Composite System - Tengteng Wang; Chunyan Zhang; Wei Zhong; Xiucheng Yang; Aiping Wang; Rongcai Liang (AAPS PharmSciTech, 2019)

Effect of Fast-Disintegrating Tablets’ Characteristics on the Sublingual Permeability of Atropine Sulfate for the Potential Treatment of Organophosphates Toxicity - Alhussain Aodah; Mohamad Rawas-Qalaji; Rawan Bafail; Mutasem Rawas-Qalaji (AAPS PharmSciTech, 2019)

Investigation of Controlled Release Molecular Mechanism of Oil Phase in Spilanthol Emulsion: Development and In Vitro, In Vivo Characterization - Degong Yang; Wanlin Li; Liang Fang; Chao Liu (AAPS PharmSciTech, 2019)

Decision Support for Excipient Risk Assessment in Pharmaceutical Manufacturing - Andres Bejarano; Chandima Hewa Nadungodage; Fang Wang; Ann Christine Catlin; Stephen W. Hoag (AAPS PharmSciTech, 2019)

Mucoadhesive In Situ Gelling Liquid Crystalline Precursor System to Improve the Vaginal Administration of Drugs - Patricia Rocha de Araújo; Giovana Maria Fioramonti Calixto; Isabel Cristiane da Silva; Lucas Henrique de Paula Zago; João Augusto Oshiro Junior; Fernando Rogério Pavan; Anderson Orzari Ribeiro; Carla Raquel Fontana; Marlus Chorilli (AAPS PharmSciTech, 2019)

Formulation of Dronedarone Hydrochloride-Loaded Proliposomes: In Vitro and In Vivo Evaluation Using Caco-2 and Rat Model - Surya Prakasarao Kovvasu; Priyanka Kunamaneni; Steven Yeung; Javier Rueda; Guru V. Betageri (AAPS PharmSciTech, 2019)

Prediction of Human Pharmacokinetics of Fomepizole from Preclinical Species Pharmacokinetics Based on Normalizing Time Course Profiles - Ravi Kumar Jairam; Sadanand Rangnathrao Mallurwar; Suresh P. Sulochana; Devaraj V. Chandrasekhar; Umesh Todmal; Ravi Kanth Bhamidipati; Wolfgang Richter; Nuggehally R. Srinivas; Ramesh Mullangi (AAPS PharmSciTech, 2019)

Crystal Transformation of β-CD-MOF Facilitates Loading of Dimercaptosuccinic Acid - Yuehuai Xiong; Li Wu; Tao Guo; Caifen Wang; Wenting Wu; Yan Tang; Ting Xiong; Yong Zhou; Weifeng Zhu; Jiwen Zhang (AAPS PharmSciTech, 2019)

Prediction of Dissolution of Sustained Release Coated Ciprofloxacin Beads Using Near-infrared Spectroscopy and Process Parameters: a Data Fusion Approach - Ahmed Ibrahim; Bhaveshkumar H. Kothari; Raafat Fahmy; Stephen W. Hoag (AAPS PharmSciTech, 2019)

Novel Hot Melt Extruded Matrices of Hydroxypropyl Cellulose and Amorphous Felodipine–Plasticized Hydroxypropyl Methylcellulose as Controlled Release Systems - Shan Yi; Jiandong Wang; Yang Lu; Ruyu Ma; Qi Gao; Shulai Liu; Subin Xiong (AAPS PharmSciTech, 2019)

Delivery of Docetaxel to Brain Employing Piperine-Tagged PLGA-Aspartic Acid Polymeric Micelles: Improved Cytotoxic and Pharmacokinetic Profiles - Anupama Singh; Nagarani Thotakura; Bhupinder Singh; Shikha Lohan; Poonam Negi; Deepak Chitkara; Kaisar Raza (AAPS PharmSciTech, 2019)

Enhancement of Oral Bioavailability and Anti-hyperuricemic Activity of Isoliquiritigenin via Self-Microemulsifying Drug Delivery System - Kangyi Zhang; Qilong Wang; Qiuxuan Yang; Qiuyu Wei; Na Man; Michael Adu-Frimpong; Elmurat Toreniyazov; Hao Ji; Jiangnan Yu; Ximing Xu (AAPS PharmSciTech, 2019)

Isolation of Itraconazole Nanostructured Microparticles via Spray Drying with Rational Selection of Optimum Base for Successful Reconstitution and Compaction - Kate P. M. McComiskey; Alan McDonagh; Lidia Tajber (AAPS PharmSciTech, 2019)

Fabrication of Dissolvable Microneedle Patches Using an Innovative Laser-Cut Mould Design to Shortlist Potentially Transungual Delivery Systems: In Vitro Evaluation - Esra’a Albarahmieh; Labiba AbuAmmouneh; Zaina Kaddoura; Farah AbuHantash; Bashar A. Alkhalidi; Alaaldeen Al-Halhouli (AAPS PharmSciTech, 2019)

Quality by Design Enabled Development of Oral Self-Nanoemulsifying Drug Delivery System of a Novel Calcimimetic Cinacalcet HCl Using a Porous Carrier: In Vitro and In Vivo Characterisation - Kahnu Charan Panigrahi; Ch. Niranjan Patra; M. E. Bhanoji Rao (AAPS PharmSciTech, 2019)

Correction to: Nondestructive Quantitative Inspection of Drug Products Using Benchtop NMR Relaxometry—the Case of NovoMix® 30 - Katharine T. Briggs; Marc B. Taraban; Weizhen Wang; Y. Bruce Yu (AAPS PharmSciTech, 2019)

A Novel Surfactant-Free O/O Paclitaxel Ointment for the Topical Treatment of Psoriasis - Xiaozhuo Yin; Xiaolei Cao; Jiaqi Li; Xu Cheng; Gang Cheng; Meijuan Zou; Hongyu Piao (AAPS PharmSciTech, 2019)

Temperature/pH-Triggered PNIPAM-Based Smart Nanogel System Loaded With Anastrozole Delivery for Application in Cancer Chemotherapy - Ajit Singh; Kalpesh Vaishagya; Rahul K. Verma; Rahul Shukla (AAPS PharmSciTech, 2019)

Designing of a pH-Triggered Carbopol®/HPMC In Situ Gel for Ocular Delivery of Dorzolamide HCl: In Vitro, In Vivo, and Ex Vivo Evaluation - Maryam Kouchak; Mina Mahmoodzadeh; Fereydoun Farrahi (AAPS PharmSciTech, 2019)

In Memoriam: Dr. Paul B. Myrdal - Philip J. Kuehl; Hugh D. Smyth; Stephen W. Stein; Robert O. Williams (AAPS PharmSciTech, 2019)

A Thermodynamic Balance Model for Liquid Film Drying Kinetics of a Tablet Film Coating and Drying Process - Bumjoon Cha; Shaun C. Galbraith; Huolong Liu; Seo-Young Park; Zhuangrong Huang; Thomas O’Connor; Sau Lee; Seongkyu Yoon (AAPS PharmSciTech, 2019)

A High-Demanding Strategy to Ensure the Highest Quality Standards of Oral Liquid Individualized Medicines for Pediatric Use - Javier Suárez-González; Ana Santoveña-Estévez; Sofía Armijo-Ruíz; Aurora Castillo; José B. Fariña (AAPS PharmSciTech, 2019)

Quantification of Inkjet-Printed Pharmaceuticals on Porous Substrates Using Raman Spectroscopy and Near-Infrared Spectroscopy - Magnus Edinger; Laura-Diana Iftimi; Daniel Markl; Mohammed Al-Sharabi; Daniel Bar-Shalom; Jukka Rantanen; Natalja Genina (AAPS PharmSciTech, 2019)

Determination of Passive Dry Powder Inhaler Aerodynamic Particle Size Distribution by Multi-Stage Cascade Impactor: International Pharmaceutical Aerosol Consortium on Regulation & Science (IPAC-RS) Recommendations to Support Both Product Quality Control and Clinical Programs - Jolyon P. Mitchell; Stephen W. Stein; William Doub; Adrian P. Goodey; J. David Christopher; Rajni B. Patel; Terrence P. Tougas; Svetlana Lyapustina (AAPS PharmSciTech, 2019)

Efficacy of Ciprofloxacin and Its Copper Complex against Pseudomonas aeruginosa Biofilms - Frederic Tewes; Tania F. Bahamondez-Canas; Hugh D. C. Smyth (AAPS PharmSciTech, 2019)

Development and Characterization of Florfenicol-Loaded BSA Nanoparticles as Controlled Release Carrier - Francisco Arriagada; Germán Günther; Irene Zabala; Jorge Rubio-Retama; Javier Morales (AAPS PharmSciTech, 2019)

Solubilization of Carbamazepine in TPGS Micelles: Effect of Temperature and Electrolyte Addition - Shubham Jain; Sonia Pandey; Priyanka Sola; Habiba Pathan; Rahul Patil; Debes Ray; Vinod K. Aswal; Pratap Bahadur; Sanjay Tiwari (AAPS PharmSciTech, 2019)

Nanostructured Lipid Carrier of Propofol: a Promising Alternative to Marketed Soybean Oil–Based Nanoemulsion - Ganesh Shevalkar; Rohan Pai; Pradeep Vavia (AAPS PharmSciTech, 2019)

Effect of Tetrabutylammonium Bromide-Based Deep Eutectic Solvents on the Aqueous Solubility of Indomethacin at Various Temperatures: Measurement, Modeling, and Prediction with Three-Dimensional Hansen Solubility Parameters - Masumeh Mokhtarpour; Hemayat Shekaari; Fleming Martinez; Mohammed Taghi Zafarani-Moattar (AAPS PharmSciTech, 2019)

An Investigation of Magnesium Stearate Mixing Performance in a V-Blender Through Passive Vibration Measurements - Austin Cameron; Lauren Briens (AAPS PharmSciTech, 2019)

Preparation of Peppermint Oil-Based Nanodevices Loaded with Paclitaxel: Cytotoxic and Apoptosis Studies in HeLa Cells - Sergio E. Flores-Villaseñor; René D. Peralta-Rodríguez; Felipe Padilla-Vaca; H. Iván Meléndez-Ortiz; Jorge C. Ramirez-Contreras; Bernardo Franco (AAPS PharmSciTech, 2019)

Formulation, Optimization, and In vivo Evaluation of Gastroretentive Drug Delivery System of Nifedipine for the Treatment of Preeclampsia - Megha N. Karemore; Jasmine G. Avari (AAPS PharmSciTech, 2019)

Reducing Burst Release Effect of Freely Water-Soluble Drug Incorporated into Gastro-Floating Formulation Below HPMC Threshold Concentration Through Interpolymer Complex - Syaiful Choiri; T. N. Saifullah Sulaiman; Abdul Rohman (AAPS PharmSciTech, 2019)

Effect of USP Induction Ports, Glass Sampling Apparatus, and Inhaler Device Resistance on Aerodynamic Patterns of Fluticasone Propionate–Loaded Engineered Mannitol Microparticles - Piyush Mehta; C. Bothiraja; Shivajirao Kadam; Atmaram Pawar (AAPS PharmSciTech, 2019)

3D Printing of Metformin HCl PVA Tablets by Fused Deposition Modeling: Drug Loading, Tablet Design, and Dissolution Studies - Mariam Ibrahim; Morgan Barnes; Robert McMillin; Daniel W. Cook; Sarah Smith; Mathew Halquist; Dayanjan Wijesinghe; Thomas D. Roper (AAPS PharmSciTech, 2019)

A Comparative Solubility Enhancement Study of Cefixime Trihydrate Using Different Dispersion Techniques - Rana M. Obaidat; Mai Khanfar; Rand Ghanma (AAPS PharmSciTech, 2019)

Nondestructive Quantitative Inspection of Drug Products Using Benchtop NMR Relaxometry—the Case of NovoMix® 30 - Katharine T. Briggs; Marc B. Taraban; Weizhen Wang; Y. Bruce Yu (AAPS PharmSciTech, 2019)

Application of Gamma Radiation on Hard Gelatin Capsules as Sterilization Technique and Its Consequences on the Chemical Structure of the Material - James Teixeira Rodrigues; Francisco Nunes de Souza Neto; Murillo Fernandes Ferreira; Plínio Lázaro Faleiro Naves; Luciana Rebelo Guilherme (AAPS PharmSciTech, 2019)

Nanoparticles: Oral Delivery for Protein and Peptide Drugs - Shu-jun Cao; Shuo Xu; Hui-ming Wang; Yong Ling; Jiahua Dong; Rui-dong Xia; Xiang-hong Sun (AAPS PharmSciTech, 2019)

Development of High-Strength Extended-Release Multiparticulate System by Crystallo-co-agglomeration Technique with Integration of Central Composite Design - Vinod L. Gaikwad; Namdeo R. Jadhav; Atmaram P. Pawar; Kakasaheb R. Mahadik (AAPS PharmSciTech, 2019)

Impacts of Polymeric Additives on Nucleation and Crystal Growth of Indomethacin from Supersaturated Solutions - Hui Cheng; Liang Mao; Shuai Zhang; Huixia Lv (AAPS PharmSciTech, 2019)

The Influence of Viscosity and Non-freezing Water Contents Bounded to Different Hydroxypropyl Celluloses (HPC) and Hydroxypropyl Methylcelluloses (HPMC) on Stability of Acetylsalicylic Acid - Przemysław Talik; Joanna Piotrowska; Urszula Hubicka (AAPS PharmSciTech, 2019)

Dual-Ligand Modification of PEGylated Liposomes Used for Targeted Doxorubicin Delivery to Enhance Anticancer Efficacy - Cong Li; Chaoyang Lai; Qiujun Qiu; Xiang Luo; Ling Hu; Huangliang Zheng; Yi Lu; Min Liu; Hongxia Zhang; Xinrong Liu; Yihui Deng; Yanzhi Song (AAPS PharmSciTech, 2019)

Design and Toxicity Evaluation of Novel Fatty Acid-Amino Acid-Based Biocompatible Surfactants - Sameer S. Katiyar; Varun Kushwah; Chander Parkash Dora; Ravindra Y. Patil; Sanyog Jain (AAPS PharmSciTech, 2019)

A Novel Phytantriol-Based In Situ Liquid Crystal Gel for Vaginal Delivery - Huang Jie; Liu Liu; Gui Shuangying; Wang Xingqi; Hu Rongfeng; Zhang Yong; Tian Chunling; Xia Mengqiu; Chu Xiaoqin (AAPS PharmSciTech, 2019)

Small-Scale Tools to Assess the Impact of Interfacial and Shear Stress on Biologic Drug Products - Maria O. Ogunyankin; Smeet Deshmukh; Mary E. Krause; Thiago Carvalho; Masano Huang; Andrew Ilott; Brenda Remy; Mehrnaz Khossravi (AAPS PharmSciTech, 2019)

Development, Optimization, and In Vitro/In Vivo Characterization of Enhanced Lipid Nanoparticles for Ocular Delivery of Ofloxacin: the Influence of Pegylation and Chitosan Coating - Hussein M. Eid; Mohammed H. Elkomy; Shahira F. El Menshawe; Heba F. Salem (AAPS PharmSciTech, 2019)

Combination of Colloidal Silicon Dioxide with Spray-Dried Solid Dispersion to Facilitate Discharge from an Agitated Dryer - Yung-Chi Lee; Michael McNevin; Craig Ikeda; Georgia Chouzouri; Justin Moser; David Harris; Logan Howell (AAPS PharmSciTech, 2019)

Nanosized Transferosome-Based Intranasal In Situ Gel for Brain Targeting of Resveratrol: Formulation, Optimization, In Vitro Evaluation, and In Vivo Pharmacokinetic Study - Heba F. Salem; Rasha M. Kharshoum; Heba A. Abou-Taleb; Demiana M. Naguib (AAPS PharmSciTech, 2019)

Mapping Fusogenicity of Ciprofloxacin-Loaded Liposomes with Bacterial Cells - Runali Patil; Arun Torris; Suresh Bhat; Sharvil Patil (AAPS PharmSciTech, 2019)

Characterization of Tetracycline Hydrochloride Compounded in a Miracle Mouthwash Formulation - Usir S. Younis; Mahdieh Fazel; Paul B. Myrdal (AAPS PharmSciTech, 2019)

Assessment of Biopharmaceutical Performance of Supersaturating Formulations of Carbamazepine in Rats Using Physiologically Based Pharmacokinetic Modeling - Samarth D. Thakore; Poonam Singh Thakur; Ganesh Shete; Rahul Gangwal; Ajit S. Narang; Abhay T. Sangamwar; Arvind Kumar Bansal (AAPS PharmSciTech, 2019)

Pressurized Metered Dose Inhaler Technology: Manufacturing - Ernest Vallorz; Poonam Sheth; Paul Myrdal (AAPS PharmSciTech, 2019)

Predictive and Accelerated Formulation Design Using Synchrotron Methods - Stephen R. Byrn; Xiaoming Sean Chen; Pamela A. Smith (AAPS PharmSciTech, 2019)

Impact of Process Parameters on Particle Size Involved in Media Milling Technique Used for Preparing Clotrimazole Nanocrystals for the Management of Cutaneous Candidiasis - Viral Patel; Om Prakash Sharma; Tejal A. Mehta (AAPS PharmSciTech, 2019)

Investigation of Effect of Isopropyl Palmitate on Drug Release from Transdermal Patch and Molecular Dynamics Study - Jiuheng Ruan; Xiaocao Wan; Peng Quan; Chao Liu; Liang Fang (AAPS PharmSciTech, 2019)

Building Process Understanding of Fluid Bed Taste Mask Coating of Microspheres - Barbara Santos Silva; Matthew Santangelo; Marie-Josée Colbert; Clémence Fauteux-Lefebvre; Jeremy A. Bartlett; Pierre-Philippe Lapointe-Garant; Ryan Gosselin (AAPS PharmSciTech, 2019)

Computational Predictability of Microsponge Properties Using Different Multivariate Models - Paresh R. Mahaparale; Bhavani Prasad Vinjamuri; Mayura S. Chavan; Mahavir B. Chougule; Rahul V. Haware (AAPS PharmSciTech, 2019)

Enhanced Permeation of Methotrexate via Loading into Ultra-permeable Niosomal Vesicles: Fabrication, Statistical Optimization, Ex Vivo Studies, and In Vivo Skin Deposition and Tolerability - Abdulaziz M. Al-mahallawi; Ahmed R. Fares; Wessam H. Abd-Elsalam (AAPS PharmSciTech, 2019)

The Influence of Electrostatic Controls on MDI Size Distribution Measurements - Stephen W. Stein; Jack Rasmussen; Sheila Walls; David W. Schultz; Claire Oakley; James B. Drake (AAPS PharmSciTech, 2019)

Effective Topical Delivery of H-AgNPs for Eradication of Klebsiella pneumoniae–Induced Burn Wound Infection - Sanjay Chhibber; Vijay Singh Gondil; Love Singla; Munish Kumar; Tanya Chhibber; Gajanand Sharma; Rohit Kumar Sharma; Nishima Wangoo; Om Prakash Katare (AAPS PharmSciTech, 2019)

Preformulation and Evaluation of Tofacitinib as a Therapeutic Treatment for Asthma - Usir S. Younis; Ernest Vallorz; Kenneth J. Addison; Julie G. Ledford; Paul B. Myrdal (AAPS PharmSciTech, 2019)

Investigating the Effect of APAP Crystals on Tablet Behavior Manufactured by Direct Compression - Nastaran Ghazi; Zhanjie Liu; Chinmay Bhatt; San Kiang; Alberto Cuitino (AAPS PharmSciTech, 2019)

Preparation, Characterization and Antioxidant Evaluation of Poorly Soluble Polyphenol-Loaded Nanoparticles for Cataract Treatment - Deepal Vora; Segewkal Heruye; Dunesh Kumari; Catherine Opere; Harsh Chauhan (AAPS PharmSciTech, 2019)

Poly (ɛ-Caprolactone) Nanoparticles with pH-Responsive Behavior Improved the In Vitro Antitumor Activity of Methotrexate - Letícia Bueno Macedo; Daniele Rubert Nogueira-Librelotto; Josiele de Vargas; Laís Engroff Scheeren; María Pilar Vinardell; Clarice Madalena Bueno Rolim (AAPS PharmSciTech, 2019)

In Vitro Drug Dissolution/Permeation Testing of Nanocarriers for Skin Application: a Comprehensive Review - Ravi Sheshala; Nor Khaizan Anuar; Nor Hayati Abu Samah; Tin Wui Wong (AAPS PharmSciTech, 2019)

Lesson Learnt from Recall of Valsartan and Other Angiotensin II Receptor Blocker Drugs Containing NDMA and NDEA Impurities - Naseem Ahmad Charoo; Areeg Anwer Ali; Shailesh Kumar Buha; Ziyaur Rahman (AAPS PharmSciTech, 2019)

Development of MART for the Rapid Production of Nanostructured Lipid Carriers Loaded with All-Trans Retinoic Acid for Dermal Delivery - Vivek M. Ghate; Arun K. Kodoth; S. Raja; B. Vishalakshi; Shaila A. Lewis (AAPS PharmSciTech, 2019)

Lecithin Microemulsion Lipogels Versus Conventional Gels for Skin Targeting of Terconazole: In Vitro, Ex Vivo, and In Vivo Investigation - Sara M. Talaat; Yosra S. R. Elnaggar; Ossama Y. Abdalla (AAPS PharmSciTech, 2019)

Translational Multi-Disciplinary Approach for the Drug and Gene Delivery Systems for Cancer Treatment - Rachna Nayak; Igor Meerovich; Alekha K. Dash (AAPS PharmSciTech, 2019)

Evaluation of Hydrogenated Soybean Phosphatidylcholine Matrices Prepared by Hot Melt Extrusion for Oral Controlled Delivery of Water-Soluble Drugs - Marina Kolbina; Adrian Schulte; Peter van Hoogevest; Martin Körber; Roland Bodmeier (AAPS PharmSciTech, 2019)

Insulin Mucoadhesive Liposomal Gel for Wound Healing: a Formulation with Sustained Release and Extended Stability Using Quality by Design Approach - Marwa H. S. Dawoud; Ghada E. Yassin; Dalia M. Ghorab; Nadia M. Morsi (AAPS PharmSciTech, 2019)

Feedforward and Feedback Control of a Pharmaceutical Coating Process - Yuxiang Zhao; James K. Drennen; Shikhar Mohan; Suyang Wu; Carl A. Anderson (AAPS PharmSciTech, 2019)

Systematically Optimized Imiquimod-Loaded Novel Hybrid Vesicles by Employing Design of Experiment (DoE) Approach with Improved Biocompatibility, Stability, and Dermatokinetic Profile - Mandeep Sharma; Gajanand Sharma; Bhupinder Singh; Om Prakash Katare (AAPS PharmSciTech, 2019)

Preparation and Evaluation of Mosapride Citrate Dual-Release Dry Suspension - Kuntang Liu; Zhengjie Meng; Yang Li; Jiwei Liu; Yan Xu; Yonglu Wang; Xueming Li (AAPS PharmSciTech, 2019)

Optimization of Stable IgG Formulation Containing Amino Acids and Trehalose During Freeze-Drying and After Storage: a Central Composite Design - Yasaman Mirfakhraei; Homa Faghihi; Amir Hossein Mohammad Zade; Majid Darabi; Alireza Vatanara (AAPS PharmSciTech, 2019)

Self-microemulsifying Drug Delivery System for Improved Oral Delivery of Limonene: Preparation, Characterization, in vitro and in vivo Evaluation - Yuan Zhu; Wen Xu; Jiajia Zhang; Youwu Liao; Caleb Kesse Firempong; Michael Adu-Frimpong; Wenwen Deng; Huiyun Zhang; Jiangnan Yu; Ximing Xu (AAPS PharmSciTech, 2019)

Optimization and Evaluation of Beclomethasone Dipropionate Micelles Incorporated into Biocompatible Hydrogel Using a Sub-Chronic Dermatitis Animal Model - Menna Assem; Omneya Mohammed Khowessah; Dalia Ghorab (AAPS PharmSciTech, 2019)

Utility of Microcrystalline Cellulose for Improving Drug Content Uniformity in Tablet Manufacturing Using Direct Powder Compression - Shohei Nakamura; Chisato Tanaka; Hiroshi Yuasa; Takatoshi Sakamoto (AAPS PharmSciTech, 2019)

Improved Oral Absorption of Poorly Soluble Curcumin via the Concomitant Use of Borneol - Ying Gao; Guo Chen; Xiaojiao Luan; Meijuan Zou; Hongyu Piao; Gang Cheng (AAPS PharmSciTech, 2019)

Cocrystal of 5-Fluorouracil: Characterization and Evaluation of Biopharmaceutical Parameters - Manoj Kumar Gautam; Mousumi Besan; Divya Pandit; Sanjay Mandal; Renu Chadha (AAPS PharmSciTech, 2019)

Performance Characteristics of a Novel Vibration Technique for the Densification of a Powder Bed within a Die of a Rotary Tablet Press — a Proof of Concept - Alexander Kalies; Hüseyin Özcoban; Claudia S. Leopold (AAPS PharmSciTech, 2019)

Highly Soluble Glimepiride and Irbesartan Co-amorphous Formulation with Potential Application in Combination Therapy - Jorge Cruz-Angeles; Marcelo Videa; Luz María Martínez (AAPS PharmSciTech, 2019)

A Thermoelectric Device for Coupling Fluid Temperature Regulation During Continuous Skin Sonoporation or Sonophoresis - Jeremy Robertson; Marie Squire; Sid Becker (AAPS PharmSciTech, 2019)

Thermally Induced Denaturing Energetics of Human Blood Plasma Albumin by Differential Scanning Calorimetry (DSC) as an Indicator for Breast Cancer Diagnosis in Female Patients - Damrongsak Faroongsarng; Somkiat Sunpaweravong; Achara Raksawong (AAPS PharmSciTech, 2019)

Preparation, Characterization, and In vitro Evaluation of Curcumin- and Resveratrol-Loaded Solid Lipid Nanoparticles - Ashwini Gumireddy; Ryann Christman; Dunesh Kumari; Amit Tiwari; E. Jeffrey North; Harsh Chauhan (AAPS PharmSciTech, 2019)

Stability and Bioavailability Enhancement of Telmisartan Ternary Solid Dispersions: the Synergistic Effect of Polymers and Drug-Polymer(s) Interactions - Xiangjun Shi; Tiantian Xu; Wan Huang; Baibai Fan; Xiaoxia Sheng (AAPS PharmSciTech, 2019)

Release Adjustment of Two Drugs with Different Solubility Combined in a Matrix Tablet - Anis Y. Chaerunisaa; Rebaz Ali; Andriy Dashevskiy (AAPS PharmSciTech, 2019)

Pharmaceutical “New Prior Knowledge”: Twenty-First Century Assurance of Therapeutic Equivalence - Ajaz S. Hussain; Vadim J. Gurvich; Kenneth Morris (AAPS PharmSciTech, 2019)

Application of the Modified Tangential Spray-Fluidized Bed to Produce Nonpareils from Primary Crystals - Ramy N. Elsergany; Lai Wah Chan; Paul Wan Sia Heng (AAPS PharmSciTech, 2019)

Development and Characterization of Microstructured, Spray-Dried Co-Amorphous Mixture of Antidiabetic Agents Stabilized by Silicate - Sarika Wairkar; Ram Gaud (AAPS PharmSciTech, 2019)

Formulation of Cinnarizine for Stabilization of Its Physiologically Generated Supersaturation - Maryam Maghsoodi; Ali Nokhodchi; Mahzad Azhdarzadeh Oskuei; Saman Heidari (AAPS PharmSciTech, 2019)

Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy - Donglei Leng; Eric Ofosu Kissi; Korbinian Löbmann; Kaushik Thanki; Elias Fattal; Thomas Rades; Camilla Foged; Mingshi Yang (AAPS PharmSciTech, 2019)

Antifungal and Mucoadhesive Properties of an Orally Administered Chitosan-Coated Amphotericin B Nanostructured Lipid Carrier (NLC) - Janet Tan Sui Ling; Clive J. Roberts; Nashiru Billa (AAPS PharmSciTech, 2019)

Erlotinib-Valproic Acid Liquisolid Formulation: Evaluating Oral Bioavailability and Cytotoxicity in Erlotinib-Resistant Non-small Cell Lung Cancer Cells - Ketan Patel; Ravi Doddapaneni; Manali Patki; Vasanthkumar Sekar; Arvind Bagde; Mandip Singh (AAPS PharmSciTech, 2019)

Buspirone Hydrochloride Loaded In Situ Nanovesicular Gel as an Anxiolytic Nasal Drug Delivery System: In Vitro and Animal Studies - Dina M. Abdelnabi; Marwa H. Abdallah; Hanaa A. Elghamry (AAPS PharmSciTech, 2019)

Optimization of Chitosan-α-casein Nanoparticles for Improved Gene Delivery: Characterization, Stability, and Transfection Efficiency - João Panão Costa; Sofia Carvalho; Sandra Jesus; Edna Soares; Ana Patrícia Marques; Olga Borges (AAPS PharmSciTech, 2019)

Preparation and Evaluation of Irinotecan Poly(Lactic-co-Glycolic Acid) Nanoparticles for Enhanced Anti-tumor Therapy - Xuehua Yang; Ying Yang; Qingwen Jia; Yanyun Hao; Jingjing Liu; Guihua Huang (AAPS PharmSciTech, 2019)

Evaluation of Bio-relevant Mouth-Throat Models for Characterization of Metered Dose Inhalers - Anubhav Kaviratna; Geng Tian; Xiaofei Liu; Renishkumar Delvadia; Sau Lee; Changning Guo (AAPS PharmSciTech, 2019)

Polyglutamic Acid Functionalization of Chitosan Nanoparticles Enhances the Therapeutic Efficacy of Insulin Following Oral Administration - Dileep Urimi; Ashish Kumar Agrawal; Varun Kushwah; Sanyog Jain (AAPS PharmSciTech, 2019)

Self-Emulsifying Oral Lipid Drug Delivery Systems: Advances and Challenges - Sarita Rani; Rafquat Rana; Gaurav K. Saraogi; Vipin Kumar; Umesh Gupta (AAPS PharmSciTech, 2019)

The Use of 3D Printed Molds to Cast Tablets with a Designed Disintegration Profile - Adil Ajmal; Ammon Meskarzadeh; Natalja Genina; Cosima Hirschberg; Johan Peter Boetker; Jukka Rantanen (AAPS PharmSciTech, 2019)

A Drug Release Model Constructed by Factorial Design to Investigate the Interaction Between Host Mesoporous Silica Carriers and Drug Molecules - Tong Liu; Keke Wang; Mingyan Jiang; Long Wan (AAPS PharmSciTech, 2019)

Respiratory Administration of Infliximab Dry Powder for Local Suppression of Inflammation - Homa Faghihi; Abdolhossein Rouholamini Najafabadi; Zahra Daman; Elham Ghasemian; Hamed Montazeri; Alireza Vatanara (AAPS PharmSciTech, 2019)

Effect of pH and Ionic Strength on the Solubility of Quinoline: Back-to-Basics - M. Teresa Carvajal; Samuel Yalkowsky (AAPS PharmSciTech, 2019)

Submission of Rifaximin to Different Techniques: Characterization, Solubility Study, and Microbiological Evaluation - Ana Carolina Kogawa; Leena Peltonen; Selma Gutierrez Antonio; Hérida Regina Nunes Salgado (AAPS PharmSciTech, 2019)

Amphotericin B-Loaded Emulgel: Effect of Chemical Enhancers on the Release Profile and Antileishmanial Activity In Vitro - Iluska Martins Pinheiro; Ivana Pereira Santos Carvalho; José Alves Terceiro Neto; Gláucia Laís Nunes Lopes; Elvilene de Sousa Coêlho; Enoque Pereira Costa Sobrinho-Júnior; Michel Mualém de Moraes Alves; Fernando Aécio de Amorim Carvalho; André Luís Menezes Carvalho (AAPS PharmSciTech, 2019)

Potential of Lipid Nanoparticles (SLNs and NLCs) in Enhancing Oral Bioavailability of Drugs with Poor Intestinal Permeability - Sushama Talegaonkar; Arundhati Bhattacharyya (AAPS PharmSciTech, 2019)

Correction to: Enhanced Oral Absorption of Amisulpride Via a Nanostructured Lipid Carrier-Based Capsules: Development, Optimization Applying the Desirability Function Approach and In Vivo Pharmacokinetic Study - Abd El-Halim I. El Assasy; Nihal Farid Younes; Amal I. A. Makhlouf (AAPS PharmSciTech, 2019)

Ethambutol-Loaded Solid Lipid Nanoparticles as Dry Powder Inhalable Formulation for Tuberculosis Therapy - Elham Nemati; Ahad Mokhtarzadeh; Vahid Panahi-Azar; Ali Mohammadi; Hamed Hamishehkar; Mehran Mesgari-Abbasi; Jafar Ezzati Nazhad Dolatabadi; Miguel de la Guardia (AAPS PharmSciTech, 2019)

pH/Thermo-Dual Responsive Tunable In Situ Cross-Linkable Depot Injectable Hydrogels Based on Poly(N-Isopropylacrylamide)/Carboxymethyl Chitosan with Potential of Controlled Localized and Systemic Drug Delivery - Samiullah Khan; Naveed Akhtar; Muhammad Usman Minhas; Syed Faisal Badshah (AAPS PharmSciTech, 2019)

QbD-Based Development of Cationic Self-nanoemulsifying Drug Delivery Systems of Paclitaxel with Improved Biopharmaceutical Attributes - Sarwar Beg; Ravinder Kaur; Rajneet Kaur Khurana; Vikas Rana; Teenu Sharma; Bhupinder Singh (AAPS PharmSciTech, 2019)

Delivery Technologies for Orally Inhaled Products: an Update - Chaeho Moon; Hugh D. C. Smyth; Alan B. Watts; Robert O. Williams (AAPS PharmSciTech, 2019)

Delivery Systems as Vital Tools in Drug Repurposing - Tori Czech; Reza Lalani; Moses O. Oyewumi (AAPS PharmSciTech, 2019)

Naringenin Cocrystals Prepared by Solution Crystallization Method for Improving Bioavailability and Anti-hyperlipidemia Effects - Wenxia Cui; Zehui He; Yongtai Zhang; Qiangyuan Fan; Nianping Feng (AAPS PharmSciTech, 2019)

Surface Dissolution UV Imaging for Investigation of Dissolution of Poorly Soluble Drugs and Their Amorphous Formulation - Chiau Ming Long; Kin Tang; Hitesh Chokshi; Nikoletta Fotaki (AAPS PharmSciTech, 2019)
The aim of this study is to investigate the dissolution properties of poorly soluble drugs from their pure form and their amorphous formulation under physiological relevant conditions for oral administration based on surface dissolution ultraviolet (UV) imaging. Dissolution of two poorly soluble drugs (cefuroxime axetil and itraconazole) and their amorphous formulations (Zinnat ® and Sporanox ® ) was studied with the Sirius Surface Dissolution Imager (SDI). Media simulating the fasted state conditions (compendial and biorelevant) with sequential media/flow rate change were used. The dissolution mechanism of cefuroxime axetil in simulated gastric fluid (SGF), fasted state simulated gastric fluid (FaSSGF) and simulated intestinal fluid (SIF) is predominantly swelling as opposed to the convective flow in fasted state simulated intestinal fluid (FaSSIF-V1), attributed to the effect of mixed micelles. For the itraconazole compact in biorelevant media, a clear upward diffusion of the dissolved itraconazole into the bulk buffer solution is observed. Dissolution of itraconazole from the Sporanox ® compact is affected by the polyethylene glycol (PEG) gelling layer and hydroxypropyl methylcellulose (HPMC) matrix, and a steady diffusional dissolution pattern is revealed. A visual representation and a quantitative assessment of dissolution properties of poorly soluble compounds and their amorphous formulation can be obtained with the use of surface dissolution imaging under in vivo relevant conditions.

Investigating the Mechanism of l-Valine in Improving the Stability of Gabapentin Combining Chemical Analysis Experiments with Computational Pharmacy - Jiaxin Wang; Lixiang Yang; Daixi Li; Ying Xu; Li Yang; Hong Zhao; Zhuangzhi Zhu; Hansen Luan; Qiong Luo (AAPS PharmSciTech, 2019)

Xylan from Pineapple Stem Waste: a Potential Biopolymer for Colonic Targeting of Anti-inflammatory Agent Mesalamine - Atsarina Larasati Anindya; Risa Dwi Oktaviani; Benita Rachel Praevina; Sophi Damayanti; Neng Fisheri Kurniati; Catur Riani; Heni Rachmawati (AAPS PharmSciTech, 2019)

Nanofiber-Mediated Sustained Delivery of Triiodothyronine: Role in Angiogenesis - Aishwarya Satish; Purna Sai Korrapati (AAPS PharmSciTech, 2019)

Solid Dispersion of Kaempferol: Formulation Development, Characterization, and Oral Bioavailability Assessment - Mariana Colombo; Gabriela de Lima Melchiades; Luana Roberta Michels; Fabrício Figueiró; Valquiria Linck Bassani; Helder Ferreira Teixeira; Letícia Scherer Koester (AAPS PharmSciTech, 2019)

Enhanced Solubility of Alkaloids by Complexation with Polycarboxylic Materials for Controlled Release Formulations: Case of Peschiera fuchsiaefolia - Kouadio Victorien Konan; Tien Canh Le; Mircea Alexandru Mateescu (AAPS PharmSciTech, 2019)

Brillouin Light Scattering: Development of a Near Century-Old Technique for Characterizing the Mechanical Properties of Materials - Aditya B. Singaraju; Dherya Bahl; Lewis L. Stevens (AAPS PharmSciTech, 2019)

Lipopolysaccharide Polyelectrolyte Complex for Oral Delivery of an Anti-tubercular Drug - Mumuni Sumaila; Poornima Ramburrun; Pradeep Kumar; Yahya E. Choonara; Viness Pillay (AAPS PharmSciTech, 2019)

Application of the SeDeM Expert System in Studies for Direct Compression Suitability on Mixture of Rhodiola Extract and an Excipient - Shulin Wan; Rui Yang; Han Zhang; Xuelian Li; Mingxian Gu; Tianbing Guan; Jianbing Ren; Huimin Sun; Chuanyun Dai (AAPS PharmSciTech, 2019)

Spray-Dried PulmoSphere™ Formulations for Inhalation Comprising Crystalline Drug Particles - Jeffry G. Weers; Danforth P. Miller; Thomas E. Tarara (AAPS PharmSciTech, 2019)

Effects of Polymer/Surfactant as Carriers on the Solubility and Dissolution of Fenofibrate Solid Dispersion - Baixue Yang; Lulu Wu; Jia Ke; Liuchenzi Zhou; Meixu Chen; Sanming Li; Xuesong Feng (AAPS PharmSciTech, 2019)

Development and In Vivo Evaluation of Ziyuglycoside I–Loaded Self-Microemulsifying Formulation for Activity of Increasing Leukocyte - Yongai Xiong; Ya Zou; Li Chen; Yingshu Xu; Sen Wang (AAPS PharmSciTech, 2019)

Beta-carotene-Encapsulated Solid Lipid Nanoparticles (BC-SLNs) as Promising Vehicle for Cancer: an Investigative Assessment - Ashay Jain; Gajanand Sharma; Kanika Thakur; Kaisar Raza; U. S. Shivhare; Gargi Ghoshal; Om Prakash Katare (AAPS PharmSciTech, 2019)

Co-delivery of Doxorubicin and Ceramide in a Liposomal Formulation Enhances Cytotoxicity in Murine B16BL6 Melanoma Cell Lines - Li Chen; Hamad Alrbyawi; Ishwor Poudel; Robert D. Arnold; R. Jayachandra Babu (AAPS PharmSciTech, 2019)

Preparation and Characterization of Syringic Acid–Loaded TPGS Liposome with Enhanced Oral Bioavailability and In Vivo Antioxidant Efficiency - Yingkun Liu; Congyong Sun; Wenjing Li; Michael Adu-Frimpong; Qilong Wang; Jiangnan Yu; Ximing Xu (AAPS PharmSciTech, 2019)

Ultrasound-Assisted Facile Synthesis of Nanostructured Hybrid Vesicle for the Nasal Delivery of Indomethacin: Response Surface Optimization, Microstructure, and Stability - Suraj S. Patil; Dipak D. Kumbhar; Jagdish V. Manwar; Rajesh G. Jadhao; Ravindra L. Bakal; Sharad Wakode (AAPS PharmSciTech, 2019)

Enhanced Transdermal Drug Delivery by Sonophoresis and Simultaneous Application of Sonophoresis and Iontophoresis - Juhyun Park; Hyowon Lee; Guei-Sam Lim; Nayoung Kim; Dongwon Kim; Yeu-Chun Kim (AAPS PharmSciTech, 2019)

Enhancement of Transdermal Delivery of Haloperidol via Spanlastic Dispersions: Entrapment Efficiency vs. Particle Size - Abdurrahman M. Fahmy; Doaa Ahmed El-Setouhy; Basant A. Habib; Saadia A. Tayel (AAPS PharmSciTech, 2019)

Assessing Aerosol Performance of a Dry Powder Carrier Formulation with Increasing Doses Using a Novel Inhaler - Stewart Yeung; Daniela Traini; Alan Tweedie; David Lewis; Tanya Church; Paul M. Young (AAPS PharmSciTech, 2019)

Recent Perspectives in Hot Melt Extrusion-Based Polymeric Formulations for Drug Delivery: Applications and Innovations - Yangmei Ren; Lan Mei; Liangxue Zhou; Gang Guo (AAPS PharmSciTech, 2019)

Effects of Drug-Polymer Interactions on Tablet Properties During the Development of Abuse-Deterrent Dosage Forms - Saikishore Meruva; Maureen D. Donovan (AAPS PharmSciTech, 2019)

RETRACTED ARTICLE: Design, Synthesis, and In Vitro Evaluation of Low Molecular Weight Protamine (LMWP)-Based Amphiphilic Conjugates as Gene Delivery Carriers - Sepideh Arabzadeh; Zeinab Amiri Tehranizadeh; Hamideh Moalemzadeh Haghighi; Fahimeh Charbgoo; Mohammad Ramezani; Fatemeh Soltani (AAPS PharmSciTech, 2019)

RETRACTED ARTICLE: Risedronate-Loaded Macroporous Gel Foam Enriched with Nanohydroxyapatite: Preparation, Characterization, and Osteogenic Activity Evaluation Using Saos-2 Cells - Nadia M. Morsi; Rehab Nabil Shamma; Nouran Osama Eladawy; Abdelfattah A. Abdelkhalek (AAPS PharmSciTech, 2019)

Matrix Tablets for Controlled Release of Drugs Incorporated Using Capillary Absorption - Uroš Maver; Marko Milojević; Jan Štos; Samo Adrenšek; Odon Planinšek (AAPS PharmSciTech, 2019)

Preparation, Pre-clinical and Clinical Evaluation of a Novel Rapidly Absorbed Celecoxib Formulation - Réka Angi; Tamás Solymosi; Nikoletta Erdősi; Tamás Jordán; Balázs Kárpáti; Orsolya Basa-Dénes; Andrea Ujhelyi; John McDermott; Chris Roe; Stuart Mair; Zsolt Ötvös; László Molnár; et al. (AAPS PharmSciTech, 2019)

Investigation of the Compatibility of the Skin PAMPA Model with Topical Formulation and Acceptor Media Additives Using Different Assay Setups - Melanie Köllmer; Parinaz Mossahebi; Elena Sacharow; Sascha Gorissen; Nicole Gräfe; Dirk-Heinrich Evers; Michael E. Herbig (AAPS PharmSciTech, 2019)

Paclitaxel-loaded Nanolipidic Carriers with Improved Oral Bioavailability and Anticancer Activity against Human Liver Carcinoma - Harshita; Md Abul Barkat; Md Rizwanullah; Sarwar Beg; Faheem Hyder Pottoo; Sahabjada Siddiqui; Farhan J. Ahmad (AAPS PharmSciTech, 2019)

In Vitro Cytotoxicity and Bioavailability of Ginsenoside-Modified Nanostructured Lipid Carrier Containing Curcumin - Ajay Vijayakumar; Rengarajan Baskaran; Jeong-Heum Baek; Pasupathi Sundaramoorthy; Bong Kyu Yoo (AAPS PharmSciTech, 2019)

Lipid-Based Nanocarriers for Lymphatic Transportation - Nikhar Vishwakarma; Anamika Jain; Rajeev Sharma; Nishi Mody; Sonal Vyas; Suresh P. Vyas (AAPS PharmSciTech, 2019)

Novel Inhalable Ciprofloxacin Dry Powders for Bronchiectasis Therapy: Mannitol–Silk Fibroin Binary Microparticles with High-Payload and Improved Aerosolized Properties - Chunxia Liu; Ling Lin; Zhengwei Huang; Qiaoli Wu; Junhuang Jiang; Li Lv; Xiaoxia Yu; Guilan Quan; Guocheng Li; Chuanbin Wu (AAPS PharmSciTech, 2019)

Methods to Assess Mixing of Pharmaceutical Powders - Allison Crouter; Lauren Briens (AAPS PharmSciTech, 2019)

Sustained Release Bilayer Tablet of Ibuprofen and Phenylephrine Hydrochloride: Preparation and Pharmacokinetics in Beagle Dogs - Chunli Zhu; Siyuan Xu; Xiaopeng Han; Wei Wang; Wei He; Lifang Yin; Lei Yang; Chao Qin (AAPS PharmSciTech, 2019)

Enhanced Oral Absorption of Amisulpride Via a Nanostructured Lipid Carrier-Based Capsules: Development, Optimization Applying the Desirability Function Approach and In Vivo Pharmacokinetic Study - Abd El-Halim I. El Assasy; Niha F. Younes; Amal I. A. Makhlouf (AAPS PharmSciTech, 2019)

Abuse Deterrent Immediate Release Egg-Shaped Tablet (Egglets) Using 3D Printing Technology: Quality by Design to Optimize Drug Release and Extraction - Pavan Kumar Nukala; Siddhant Palekar; Manali Patki; Ketan Patel (AAPS PharmSciTech, 2019)

Folate-Functionalized Thiomeric Nanoparticles for Enhanced Docetaxel Cytotoxicity and Improved Oral Bioavailability - Muhammad Sajjad; Muhammad Imran Khan; Sara Naveed; Sana Ijaz; Omer Salman Qureshi; Syed Atif Raza; Gul Shahnaz; Muhammad Farhan Sohail (AAPS PharmSciTech, 2019)