Spray-Dried Succinylated Soy Protein Microparticles for Oral Ibuprofen Delivery - Maria Antonieta Anaya Castro; Isabelle Alric; Fabien Brouillet; Jérôme Peydecastaing; Sophie Girod Fullana; Vanessa Durrieu (AAPS PharmSciTech, 2019)

Effect of Mild Hyperthermia on Transdermal Absorption of Nicotine from Patches - Apoorva Panda; Purnendu Kumar Sharma; S. Narasimha Murthy (AAPS PharmSciTech, 2019)

Optimal Selection of Incoming Materials from the Inventory for Achieving the Target Drug Release Profile of High Drug Load Sustained-Release Matrix Tablet - Yi Zhang; Bing Xu; Xin Wang; Shengyun Dai; Xinyuan Shi; Yanjiang Qiao (AAPS PharmSciTech, 2019)

Development and Characterization of a Self-Nanoemulsifying Drug Delivery System Comprised of Rice Bran Oil for Poorly Soluble Drugs - Georgios K. Eleftheriadis; Panagiota Mantelou; Christina Karavasili; Paschalina Chatzopoulou; Dimitrios Katsantonis; Maria Irakli; Aggeliki Mygdalia; Ioannis S. Vizirianakis; Dimitrios G. Fatouros (AAPS PharmSciTech, 2019)

Formulation and Evaluation of a Novel Oral Oil-Based Suspension Using Micro-environmental pH-Modifying Solid Dispersion - Shudong Zhang; Qiang Wan; Yidan Xing; Jiafeng Ding; Shizhuang Yang; Weiwei Sun; Mengmeng Lu; Baoliang Pan (AAPS PharmSciTech, 2019)

Oral Delivery of Methylthioadenosine to the Brain Employing Solid Lipid Nanoparticles: Pharmacokinetic, Behavioral, and Histopathological Evidences - Pramod Kumar; Gajanand Sharma; Varun Gupta; Ramanpreet Kaur; Kanika Thakur; Ruchi Malik; Anil Kumar; Naveen Kaushal; Om Prakash Katare; Kaisar Raza (AAPS PharmSciTech, 2019)

Pediatric Formulations: Knowledge Gaps Limiting the Expedited Preclinical to Clinical Translation in Children - Monika Lavan; Stephen R. Byrn; Gregory Knipp (AAPS PharmSciTech, 2019)

Distribution of Protein Content and Number of Aggregates in Monoclonal Antibody Formulation After Large-Scale Freezing - Astrid Hauptmann; Georg Hoelzl; Thomas Loerting (AAPS PharmSciTech, 2019)

Application of Texture Analysis Technique in Formulation Development of Lyophilized Orally Disintegrating Tablets Containing Mannitol, Polyvinylpyrrolidone and Amino Acids - Ellen Hackl; Irina Ermolina (AAPS PharmSciTech, 2019)

Detailed Morphological Characterization of Nanocrystalline Active Ingredients in Solid Oral Dosage Forms Using Atomic Force Microscopy - Kumiko Sakai-Kato; Kunie Nanjo; Yuki Takechi-Haraya; Yukihiro Goda; Haruhiro Okuda; Ken-ichi Izutsu (AAPS PharmSciTech, 2019)

An Evaluation of Curcumin-Encapsulated Chitosan Nanoparticles for Transdermal Delivery - Rajesh Sreedharan Nair; Andrew Morris; Nashiru Billa; Chee-Onn Leong (AAPS PharmSciTech, 2019)

Structure-Based Gastro-Retentive and Controlled-Release Drug Delivery with Novel 3D Printing - Haoyang Wen; Bosai He; Haoyu Wang; Fen Chen; Pingfei Li; Mengsuo Cui; Qijun Li; Weisan Pan; Xinggang Yang (AAPS PharmSciTech, 2019)

Multi-Layered Nanomicelles as Self-Assembled Nanocarrier Systems for Ocular Peptide Delivery - Abhirup Mandal; Pratikkumar Patel; Dhananjay Pal; Ashim K. Mitra (AAPS PharmSciTech, 2019)

Development of Theranostic Perfluorocarbon Nanoemulsions as a Model Non-Opioid Pain Nanomedicine Using a Quality by Design (QbD) Approach - Michele Herneisey; Lu Liu; Eric Lambert; Nicholas Schmitz; Shannon Loftus; Jelena M. Janjic (AAPS PharmSciTech, 2019)

Formation Mechanism, In vitro and In vivo Evaluation of Dimpled Exenatide Loaded PLGA Microparticles Prepared by Ultra-Fine Particle Processing System - Chune Zhu; Tingting Peng; Di Huang; Disang Feng; Xinyi Wang; Xin Pan; Wen Tan; Chuanbin Wu (AAPS PharmSciTech, 2019)

Characterization of the Solid Physical State of API and Its Distribution in Pharmaceutical Hot Melt Extrudates Using Terahertz Raman Imaging - Mohammed Ibrahim; Jiaxiang Zhang; Michael Repka; Rui Chen (AAPS PharmSciTech, 2019)

Aggregation Behavior of Medium Chain Fatty Acids Studied by Coarse-Grained Molecular Dynamics Simulation - Md Shakhawath Hossain; Staffan Berg; Christel A. S. Bergström; Per Larsson (AAPS PharmSciTech, 2019)

Promising Chitosan-Coated Alginate-Tween 80 Nanoparticles as Rifampicin Coadministered Ascorbic Acid Delivery Carrier Against Mycobacterium tuberculosis - Ivana R. Scolari; Paulina L. Páez; Mariela E. Sánchez-Borzone; Gladys E. Granero (AAPS PharmSciTech, 2019)

Design and Development of Lidocaine Microemulsions for Transdermal Delivery - Yaping Wang; Xihui Wang; Xiangyu Wang; Yilei Song; Xiaodan Wang; Jifu Hao (AAPS PharmSciTech, 2019)

Insights on Oral Drug Delivery of Lipid Nanocarriers: a Win-Win Solution for Augmenting Bioavailability of Antiretroviral Drugs - Bushra Nabi; Saleha Rehman; Sanjula Baboota; Javed Ali (AAPS PharmSciTech, 2019)

PBPK Absorption Modeling of Food Effect and Bioequivalence in Fed State for Two Formulations with Crystalline and Amorphous Forms of BCS 2 Class Drug in Generic Drug Development - Jereb Rebeka; Opara Jerneja; Legen Igor; Petek Boštjan; Bajc Aleksander; Žakelj Simon; Kristl Albin (AAPS PharmSciTech, 2019)

Design, Development, and Characterization of Imiquimod-Loaded Chitosan Films for Topical Delivery - Buddhadev Layek; Saif S. Rahman Nirzhor; Sneha Rathi; Karunya K. Kandimalla; Timothy S. Wiedmann; Swayam Prabha (AAPS PharmSciTech, 2019)

Measurement of Aerodynamic Particle Size Distribution of Orally Inhaled Products by Cascade Impactor: How to Let the Product Specification Drive the Quality Requirements of the Cascade Impactor - Daryl L. Roberts; Jolyon P. Mitchell (AAPS PharmSciTech, 2019)

Taste Evaluation by Electronic Tongue and Bioavailability Enhancement of Efavirenz - Monica R. P. Rao; Kirti Bhutada; Pauroosh Kaushal (AAPS PharmSciTech, 2019)

The Impact of Serum Proteins and Surface Chemistry on Magnetic Nanoparticle Colloidal Stability and Cellular Uptake in Breast Cancer Cells - Wid Mekseriwattana; Supreeya Srisuk; Ruttanaporn Kriangsaksri; Nuttawee Niamsiri; Kanlaya Prapainop (AAPS PharmSciTech, 2019)

Preparation and Characterization of an Oral Norethindrone Sustained Release/Controlled Release Nanoparticles Formulation Based on Chitosan - Bashar M. Altaani; Suhair S. Al-Nimry; Razan H. Haddad; Rana Abu-Dahab (AAPS PharmSciTech, 2019)

Antioxidant Potential and Angiotensin-Converting Enzyme (ACE) Inhibitory Activity of Orotic Acid-Loaded Gum Arabic Nanoparticles - Abdelkader Hassani; Siti Aslina Hussain; Norhafizah Abdullah; Suryani Kamarudin; Rozita Rosli (AAPS PharmSciTech, 2019)

Paclitaxel Encapsulation into Dual-Functionalized Multi-Walled Carbon Nanotubes - Vishakha Rathod; Rahul Tripathi; Parth Joshi; Prafulla K. Jha; Pratap Bahadur; Sanjay Tiwari (AAPS PharmSciTech, 2019)

IGF-II-Conjugated Nanocarrier for Brain-Targeted Delivery of p11 Gene for Depression - Manit Gandhi; Priyanka Bhatt; Gaurav Chauhan; Sarita Gupta; Ambikanandan Misra; Rajashree Mashru (AAPS PharmSciTech, 2019)

Incorporation of 3,3′-Diindolylmethane into Nanocapsules Improves Its Photostability, Radical Scavenging Capacity, and Cytotoxicity Against Glioma Cells - Juliane Mattiazzi; Marcel Henrique Marcondes Sari; Renata Lautenchleger; Morgana Dal Prá; Elizandra Braganhol; Letícia Cruz (AAPS PharmSciTech, 2019)

Bacterial Ghosts Carrying 5-Fluorouracil: A Novel Biological Carrier for Targeting Colorectal Cancer - Abdullah M. E. Youssof; Fars K. Alanazi; Mounir M. Salem-Bekhit; Faiyaz Shakeel; Nazrul Haq (AAPS PharmSciTech, 2019)

Understanding the Potential for Dissolution Simulation to Explore the Effects of Medium Viscosity on Particulate Dissolution - Deirdre M. D’Arcy; Tim Persoons (AAPS PharmSciTech, 2019)

Drug-Lipid-Surfactant Miscibility for the Development of Solid Lipid Nanoparticles - Anne Trivino; Ashwini Gumireddy; Harsh Chauhan (AAPS PharmSciTech, 2019)

Quality by Design Approach for Developing Lipid-Based Nanoformulations of Gliclazide to Improve Oral Bioavailability and Anti-Diabetic Activity - Pravin Patel; Sravanthi Reddy Pailla; Nagarjun Rangaraj; Hanumanth Srikanth Cheruvu; Sujatha Dodoala; Sunitha Sampathi (AAPS PharmSciTech, 2019)

Novel Drug Delivery Approach via Self-Microemulsifying Drug Delivery System for Enhancing Oral Bioavailability of Asenapine Maleate: Optimization, Characterization, Cell Uptake, and In Vivo Pharmacokinetic Studies - Mitali H. Patel; Veenu P. Mundada; Krutika K. Sawant (AAPS PharmSciTech, 2019)

3D-Printed Isoniazid Tablets for the Treatment and Prevention of Tuberculosis—Personalized Dosing and Drug Release - Heidi Öblom; Jiaxiang Zhang; Manjeet Pimparade; Isabell Speer; Maren Preis; Michael Repka; Niklas Sandler (AAPS PharmSciTech, 2019)
The aim of the present work was to produce 3D-printed oral dosage forms with a sufficient drug dose displaying various release profiles. Hot-melt extrusion was utilized to produce drug-loaded feedstock material that was subsequently 3D-printed into 6, 8, and 10 × 2.5 mm tablets with 15% and 90% infill levels. The prepared formulations contained 30% ( w / w ) isoniazid in combination with one or multiple pharmaceutical polymers possessing suitable properties for oral drug delivery. Thirteen formulations were successfully hot-melt extruded of which eight had properties suitable for fused deposition modeling 3D printing. Formulations containing HPC were found to be superior regarding printability in this study. Filaments with a breaking distance below 1.5 mm were observed to be too brittle to be fed into the printer. In addition, filaments with high moisture uptake at high relative humidity generally failed to be printable. Different release profiles for the 3D-printed tablets were obtained as a result of using different polymers in the printed formulations. For 8 mm tablets printed with 90% infill, 80% isoniazid release was observed between 40 and 852 min. Drug release characteristics could further be altered by changing the infill or the size of the printed tablets allowing personalization of the tablets. This study presents novel formulations containing isoniazid for prevention of latent tuberculosis and investigates 3D printing technology for personalized production of oral solid dosage forms enabling adjustable dose and drug release properties.

Drug-Phospholipid Complex—a Go Through Strategy for Enhanced Oral Bioavailability - Kaushik Kuche; Nallamothu Bhargavi; Chander Parkash Dora; Sanyog Jain (AAPS PharmSciTech, 2019)

Drug–Lipid Conjugates for Enhanced Oral Drug Delivery - Tushar Date; Kaushani Paul; Navneet Singh; Sanyog Jain (AAPS PharmSciTech, 2019)

Convective Drying Kinetics of Polymer Strip Films Loaded with a BCS Class II Drug - A. T. Naseri; E. Cetindag; J. Forte; E. Bilgili; Rajesh N. Davé (AAPS PharmSciTech, 2019)

Stability of Vaccines - N. Dumpa; K. Goel; Yuhan Guo; H. McFall; Amit Raviraj Pillai; Ashay Shukla; M. A. Repka; S. Narasimha Murthy (AAPS PharmSciTech, 2019)

New Insights on Solid-State Changes in the Levothyroxine Sodium Pentahydrate during Dehydration and its Relationship to Chemical Instability - Harsh S. Shah; Kaushalendra Chaturvedi; Mazen Hamad; Simon Bates; Ajaz Hussain; Kenneth Morris (AAPS PharmSciTech, 2019)

A Novel Simulation-Based Approach for Comparing the Population Against Average Bioequivalence Statistical Test for the Evaluation of Nasal Spray Products on Spray Pattern and Droplet Size Distribution Parameters - Jernej Grmaš; Vesna Lužar-Stiffler; Rok Dreu; Rade Injac (AAPS PharmSciTech, 2019)

A Combined Utilization of Plasdone-S630 and HPMCAS-HF in Ziprasidone Hydrochloride Solid Dispersion by Hot-Melt Extrusion to Enhance the Oral Bioavailability and No Food Effect - Xu Xue; Guoguang Chen; Xiaoqing Xu; Jin Wang; Jingjing Wang; Lili Ren (AAPS PharmSciTech, 2019)

Mechanical Properties of Topical Anti-Psoriatic Medicines: Implications for Patient Satisfaction with Treatment - A. Teixeira; V. Vasconcelos; M. Teixeira; V. Almeida; R. Azevedo; T. Torres; J. M. Sousa Lobo; P. C. Costa; I. F. Almeida (AAPS PharmSciTech, 2019)

On the Stability of Nano-formulations Prepared by Direct Synthesis: Simulated Ostwald Ripening of a Typical Nanocrystal Distribution Post-nucleation - Peter J. Skrdla; Husheng Yang (AAPS PharmSciTech, 2019)

A Novel Phytantriol-Based Lyotropic Liquid Crystalline Gel for Efficient Ophthalmic Delivery of Pilocarpine Nitrate - Xingqi Wang; Yong Zhang; Jie Huang; Chunling Tian; Mengqiu Xia; Liu Liu; Zhengguang Li; Jiaojiao Cao; Shuangying Gui; Xiaoqin Chu (AAPS PharmSciTech, 2019)

Determination of Mycoplasma hyopneumoniae-Specific IgG, IgG1, and IgG2a Titers in BALB/c Mice Induced by Mineral Oil-Based Oil-in-Water Emulsion Adjuvants Prepared Using a Self-Emulsifying Drug Delivery System - Rakesh Bastola; Jo-Eun Seo; Gyubin Noh; Taekwang Keum; Ju Hun Kim; Jong Il Shin; Sooyeun Lee; Sangkil Lee (AAPS PharmSciTech, 2019)

Lipid Nanoemulsions of Rebamipide: Formulation, Characterization, and In Vivo Evaluation of Pharmacokinetic and Pharmacodynamic Effects - Arjun Narala; Swathi Guda; Kishan Veerabrahma (AAPS PharmSciTech, 2019)

Predicting the Effects of Different Triazole Antifungal Agents on the Pharmacokinetics of Tamoxifen - Lu Chen; Liqin Zhu; Mengxue Li; Na Li; Fang Qi; Nan Wang (AAPS PharmSciTech, 2019)

Agranulocytosis-Protective Olanzapine-Loaded Nanostructured Lipid Carriers Engineered for CNS Delivery: Optimization and Hematological Toxicity Studies - Dnyandev G. Gadhave; Amol A. Tagalpallewar; Chandrakant R. Kokare (AAPS PharmSciTech, 2019)

A Mechanistic Approach To Model the Compression Cycle of Different Toolings Based on Compression Roller Interactions - Rohit P. Dugar; Robert Sedlock; Chris Offenburger; Rutesh H. Dave (AAPS PharmSciTech, 2019)

Mucoadhesive Polymeric Films to Enhance Barbaloin Penetration Into Buccal Mucosa: a Novel Approach to Chemoprevention - Giulia Di Prima; Alice Conigliaro; Viviana De Caro (AAPS PharmSciTech, 2019)

Development of Valsartan Floating Matrix Tablets Using Low Density Polypropylene Foam Powder: In vitro and In vivo Evaluation - Mohamed Rahamathulla; S. Saisivam; H. V. Gangadharappa (AAPS PharmSciTech, 2019)

Topical Delivery of Artemisone, Clofazimine and Decoquinate Encapsulated in Vesicles and Their In vitro Efficacy Against Mycobacterium tuberculosis - Lindi van Zyl; Joe M. Viljoen; Richard K. Haynes; Marique Aucamp; Andile H. Ngwane; Jeanetta du Plessis (AAPS PharmSciTech, 2019)

5β-Cholanic Acid/Glycol Chitosan Self-Assembled Nanoparticles (5β-CHA/GC-NPs) for Enhancing the Absorption of FDs and Insulin by Rat Intestinal Membranes - Chengyun Yan; Jiwei Gu; Yuguang Lv; Weiguo Shi; Zhan Huang; Ying Liao (AAPS PharmSciTech, 2019)

Systematic Evaluation of a Diclofenac-Loaded Carboxymethyl Cellulose-Based Wound Dressing and Its Release Performance with Changing pH and Temperature - Tina Maver; Lidija Gradišnik; Dragica Maja Smrke; Karin Stana Kleinschek; Uroš Maver (AAPS PharmSciTech, 2019)

In Situ Cocrystallization of Dapsone and Caffeine during Fluidized Bed Granulation Processing - Valerio Todaro; Zelalem Ayenew Worku; Lucio Mendes Cabral; Anne Marie Healy (AAPS PharmSciTech, 2019)

Influence of Dissolution Vessel Geometry and Dissolution Medium on In Vitro Dissolution Behaviour of Triamterene-Coated Model Stents in Different Test Setups - Katharina Pruessmann; Monika Wentzlaff; Ruprecht Schilling; Anne Seidlitz (AAPS PharmSciTech, 2019)

Manufacturing of Multi-drug Formulations with Customised Dose by Solvent Impregnation of Mesoporous Silica Tablets - Marek Šoltys; Sarah Akhlasová; Aleš Zadražil; Pavel Kovačík; František Štěpánek (AAPS PharmSciTech, 2019)

Tunable Properties of Poly-DL-Lactide-Monomethoxypolyethylene Glycol Porous Microparticles for Sustained Release of Polyethylenimine-DNA Polyplexes - Treniece L. Terry; Brittany E. Givens; Victor G. J. Rodgers; Aliasger K. Salem (AAPS PharmSciTech, 2019)

Cryogenic Fabrication of Dry Powders to Enhance the Solubility of a Promising Anticancer Drug, SHetA2, for Oral Administration - Mariam Ibrahim; Manolya Kukut Hatipoglu; Lucila Garcia-Contreras (AAPS PharmSciTech, 2019)

Exploring the Nano Spray-Drying Technology as an Innovative Manufacturing Method for Solid Lipid Nanoparticle Dry Powders - Krystyna Glaubitt; Maurizio Ricci; Stefano Giovagnoli (AAPS PharmSciTech, 2019)

Surface-Activated Fibre-Like SBA-15 as Drug Carriers for Bone Diseases - Magdalena Prokopowicz; Jacek Żeglinski; Adrian Szewczyk; Adrianna Skwira; Gavin Walker (AAPS PharmSciTech, 2019)

Critical In Vitro Characterization Methods of Lipid-Based Formulations for Oral Delivery: a Comprehensive Review - Nitin Kumar Swarnakar; Natarajan Venkatesan; Guru Betageri (AAPS PharmSciTech, 2019)

Use of Risk Assessment and Plackett–Burman Design for Developing Resveratrol Spray-Dried Emulsions: a Quality-by-Design Approach - Pontip Benjasirimongkol; Suchada Piriyaprasarth; Kunikazu Moribe; Pornsak Sriamornsak (AAPS PharmSciTech, 2019)

Active Targeting of Drugs and Bioactive Molecules via Oral Administration by Ligand-Conjugated Lipidic Nanocarriers: Recent Advances - A. B. Shreya; Sushil Yadaorao Raut; Renuka Suresh Managuli; Nayanabhirama Udupa; Srinivas Mutalik (AAPS PharmSciTech, 2019)

Folic Acid-Functionalized Gold Nanorods for Controlled Paclitaxel Delivery: In Vitro Evaluation and Cell Studies - Ligeri Papaioannou; Athina Angelopoulou; Sophia Hatziantoniou; Maria Papadimitriou; Panagiotis Apostolou; Ioannis Papasotiriou; Konstantinos Avgoustakis (AAPS PharmSciTech, 2019)

The Influence of Cellulosic Polymer’s Variables on Dissolution/Solubility of Amorphous Felodipine and Crystallization Inhibition from a Supersaturated State - Nian-Qiu Shi; Ying Jin; Yong Zhang; Xiao-Xia Che; Xiao Xiao; Gui-Hua Cui; Yu-Zhou Chen; Bo Feng; Zheng-Qiang Li; Xian-Rong Qi (AAPS PharmSciTech, 2019)

Recent Advances in Formulation Strategies for Efficient Delivery of Vitamin D - Rahul Gupta; Chittaranjan Behera; Gourav Paudwal; Neha Rawat; Ashish Baldi; Prem N. Gupta (AAPS PharmSciTech, 2019)

Solubility Prediction of Drugs in Binary Solvent Mixtures at Various Temperatures Using a Minimum Number of Experimental Data Points - Sina Dadmand; Farzin Kamari; William E. Acree; Abolghasem Jouyban (AAPS PharmSciTech, 2019)

In vitro SPF and Photostability Assays of Emulsion Containing Nanoparticles with Vegetable Extracts Rich in Flavonoids - Letícia Caramori Cefali; Janaína Artem Ataide; Samara Eberlin; Fernanda Cristina da Silva Gonçalves; Ana Rita Fernandes; Joana Marto; Helena Margarida Ribeiro; Mary Ann Foglio; Priscila Gava Mazzola; Eliana Barbosa Souto (AAPS PharmSciTech, 2019)

Solid-State Characterization of Three Polymorphs of an Orally Available Analog of Diethylenetriaminepentaacetic Acid - Carla Coste Sanchez; Arjun Kalra; Tonglei Li; Michael Jay (AAPS PharmSciTech, 2019)

Novel Dissolution Method for Oral Film Preparations with Modified Release Properties - Isabell Speer; Maren Preis; Jörg Breitkreutz (AAPS PharmSciTech, 2019)

Moisture Monitoring in Fluid-Bed Granulation by Multi-Resonance Microwave Sensor: Applicability on Crystal-Water Containing Donepezil Granules - Johanna Peters; Wolfgang Taute; Claas Döscher; Michael Höft; Reinhard Knöchel; Jörg Breitkreutz (AAPS PharmSciTech, 2019)

Brain Microdialysis Study of Vancomycin in the Cerebrospinal Fluid After Intracerebroventricular Administration in Mice - Yusuke Miura; Yuki Fuchigami; Sakiko Nomura; Koyo Nishimura; Masayori Hagimori; Shigeru Kawakami (AAPS PharmSciTech, 2019)

Stability, Cytotoxicity, and Retinal Pigment Epithelial Cell Binding of Hyaluronic Acid-Coated PLGA Nanoparticles Encapsulating Lutein - Chuda Chittasupho; Penpitcha Posritong; Pakaporn Ariyawong (AAPS PharmSciTech, 2019)

Inhibition of Co-Crystallization of Olmesartan Medoxomil and Hydrochlorothiazide for Enhanced Dissolution Rate in Their Fixed Dose Combination - Magdy M. Abdelquader; Ebtessam A. Essa; Gamal M. El Maghraby (AAPS PharmSciTech, 2019)

Global Regulatory Landscape - Yoshihiro Matsuda (AAPS PharmSciTech, 2019)

Raman Spectroscopy for Process Analytical Technologies of Pharmaceutical Secondary Manufacturing - Brigitta Nagy; Attila Farkas; Enikő Borbás; Panna Vass; Zsombor Kristóf Nagy; György Marosi (AAPS PharmSciTech, 2019)

The Journey to AAPS 2020: a Reflection from Strategic Planning to PharmSci 360 - Joseph W. Polli; Christopher R. McCurdy; Dale Eric Wurster; Binodh S. DeSilva; Annette Bak; Reina Bendayan; Bernd Meibohm; Allen C. Templeton; William Weiser (AAPS PharmSciTech, 2018)

Skin Penetration and Permeation Properties of Transcutol®—Neat or Diluted Mixtures - David W. Osborne; Jasmine Musakhanian (AAPS PharmSciTech, 2018)

Enhanced Understanding of Pharmaceutical Materials Through Advanced Characterisation and Analysis - Ana Patricia Ferreira; John F. Gamble; Michael M. Leane; Hyunsoo Park; Dolapo Olusanmi; Mike Tobyn (AAPS PharmSciTech, 2018)

Power of the Dissolution Test in Distinguishing a Change in Dosage Form Critical Quality Attributes - Vivian A. Gray (AAPS PharmSciTech, 2018)

Augmentation of Fluvastatin Cytotoxicity Against Prostate Carcinoma PC3 Cell Line Utilizing Alpha Lipoic–Ellagic Acid Nanostructured Lipid Carrier Formula - Usama A. Fahmy (AAPS PharmSciTech, 2018)

Formulation, Characterization, and Pharmacokinetic Studies of 6-Gingerol-Loaded Nanostructured Lipid Carriers - Qiuyu Wei; Qiuxuan Yang; Qilong Wang; Congyong Sun; Yuan Zhu; Ya Niu; Jiangnan Yu; Ximing Xu (AAPS PharmSciTech, 2018)

Green Synthesis of Carbon Nanotubes-Reinforced Molecularly Imprinted Polymer Composites for Drug Delivery of Fenbufen - Xin-Lu Liu; Hong-Fei Yao; Mei-Hong Chai; Wei He; Yan-Ping Huang; Zhao-Sheng Liu (AAPS PharmSciTech, 2018)

In Vivo Evaluation of Taste-Masked Fast-Disintegrating Sublingual Tablets of Epinephrine Microcrystals - Ousama Rachid; Keith J. Simons; Mutasem Rawas-Qalaji (AAPS PharmSciTech, 2018)

Novel Random Triblock Copolymers for Sustained Delivery of Macromolecules for the Treatment of Ocular Diseases - Mary Joseph Ngatuni; Hoang M. Trinh; Dhananjay Pal; Ashim K. Mitra (AAPS PharmSciTech, 2018)

Lipomers (Lipid-polymer Hybrid Particles) of Vardenafil Hydrochloride: a Promising Dual Platform for Modifying the Drug Release Rate and Enhancing Its Oral Bioavailability - Mai Ahmed Tawfik; Mina Ibrahim Tadros; Magdy Ibrahim Mohamed (AAPS PharmSciTech, 2018)

Radiolabeling of Preformed Niosomes with [99mTc]: In Vitro Stability, Biodistribution, and In Vivo Performance - Ameneh Almasi; Soraya Shahhosseini; Azadeh Haeri; Fariba Johari Daha; Parham Geramifar; Simin Dadashzadeh (AAPS PharmSciTech, 2018)

Intranasal Surface-Modified Mosapride Citrate-Loaded Nanostructured Lipid Carriers (MOS-SMNLCs) for Treatment of Reflux Diseases: In vitro Optimization, Pharmacodynamics, and Pharmacokinetic Studies - Reham Waheed Hammad; Rania Abdel Baset Sanad; Nevine Shawky Abdelmalk; Randa Latif Aziz; Faisal A. Torad (AAPS PharmSciTech, 2018)

Aggregate Elasticity and Tabletability of Molecular Solids: a Validation and Application of Powder Brillouin Light Scattering - Dherya Bahl; Aditya B. Singaraju; Lewis L. Stevens (AAPS PharmSciTech, 2018)

Investigating a Novel Hot Melt Extrusion-Based Drying Technique to Solidify an Amorphous Nanosuspension Using Design of Experiment Methodology - Bhavin Y. Gajera; Dhaval A. Shah; Rutesh H. Dave (AAPS PharmSciTech, 2018)

Preparation and Characterization of an Oral Vaccine Formulation Using Electrosprayed Chitosan Microparticles - Jorge Alberto S. Moreno; Danai-Anastasia Panou; Karen Stephansen; Ioannis S. Chronakis; Anja Boisen; Ana C. Mendes; Line Hagner Nielsen (AAPS PharmSciTech, 2018)

Comparing a Statistical Model and Bayesian Approach to Establish the Design Space for the Coating of Ciprofloxacin HCl Beads at Different Scales of Production - Bhaveshkumar H. Kothari; Raafat Fahmy; H. Gregg Claycamp; Christine M. V. Moore; Sharmista Chatterjee; Stephen W. Hoag (AAPS PharmSciTech, 2018)

Nano-lipid Complex of Rutin: Development, Characterisation and In Vivo Investigation of Hepatoprotective, Antioxidant Activity and Bioavailability Study in Rats - G. S. Ravi; R. Narayana Charyulu; Akhilesh Dubey; Prabhakara Prabhu; Srinivas Hebbar; Avril Candida Mathias (AAPS PharmSciTech, 2018)

Enhanced Oral Bioavailability of Chlormadinone Acetate through a Self-Microemulsifying Drug Delivery System for a Potential Dose Reduction - Jia Zeng; Jianxing Chen; Liangkang Chen; Wei Zheng; Yunfeng Cao; Ting Huang (AAPS PharmSciTech, 2018)

In-Line Film Coating Thickness Estimation of Minitablets in a Fluid-Bed Coating Equipment - Gregor Podrekar; Domen Kitak; Andraž Mehle; Zoran Lavrič; Boštjan Likar; Dejan Tomaževič; Rok Dreu (AAPS PharmSciTech, 2018)

Intratumoral Injection Administration of Irinotecan-Loaded Microspheres: In Vitro and In Vivo Evaluation - Shengjun Zhu; Mingjin Dou; Guihua Huang (AAPS PharmSciTech, 2018)

Interactions Between Biological Products and Product Packaging and Potential Approaches to Overcome Them - Minjia Wang; Yusheng Li; Priyanka Srinivasan; Zhiqing Hu; Rui Wang; Anggrida Saragih; M. A. Repka; S. N. Murthy (AAPS PharmSciTech, 2018)

Nanocarrier-Based Combination Chemotherapy for Resistant Tumor: Development, Characterization, and Ex Vivo Cytotoxicity Assessment - Sarjana Raikwar; Sonal Vyas; Rajeev Sharma; Nishi Mody; Surbhi Dubey; Suresh P. Vyas (AAPS PharmSciTech, 2018)

Bioavailability Enhancement of Aripiprazole Via Silicosan Particles: Preparation, Characterization and In vivo Evaluation - Azza A. Mahmoud; Alaa H. Salama; Rehab N. Shamma; Faten Farouk (AAPS PharmSciTech, 2018)

Enhancement in the Transdermal and Localized Delivery of Honokiol Through Breast Tissue - Xinyi Gao; Meera Gujjar Patel; Pooja Bakshi; Dipali Sharma; Ajay K. Banga (AAPS PharmSciTech, 2018)

Mechanical Characterization and Dissolution of Chewing Gum Tablets (CGTs) Containing Co-compressed Health in Gum® and Curcumin/Cyclodextrin Inclusion Complex - Turki Al Hagbani; Christopher Altomare; Mohammad M. Kamal; Sami Nazzal (AAPS PharmSciTech, 2018)

Lipid-Based Oral Formulation Strategies for Lipophilic Drugs - Vivek Patel; Rohan Lalani; Denish Bardoliwala; Saikat Ghosh; Ambikanandan Misra (AAPS PharmSciTech, 2018)

Virtual Prototyping and Parametric Design of 3D-Printed Tablets Based on the Solution of Inverse Problem - Matěj Novák; Tereza Boleslavská; Zdeněk Grof; Adam Waněk; Aleš Zadražil; Josef Beránek; Pavel Kovačík; František Štěpánek (AAPS PharmSciTech, 2018)

Physicochemical and In Vitro Evaluation of Drug Delivery of an Antibacterial Synthetic Benzophenone in Biodegradable PLGA Nanoparticles - Gabriella Costabile; Kathrin I. Gasteyer; Venkatereddy Nadithe; Katherine Van Denburgh; Qian Lin; Shiv Sharma; Joshua J. Reineke; Steven M. Firestine; Olivia M. Merkel (AAPS PharmSciTech, 2018)

Repositioning of Anti-parasitic Drugs in Cyclodextrin Inclusion Complexes for Treatment of Triple-Negative Breast Cancer - Josefina Priotti; María Virginia Baglioni; Agustina García; María José Rico; Darío Leonardi; María Celina Lamas; Mauricio Menacho Márquez (AAPS PharmSciTech, 2018)

Preparation and Evaluation of Probucol-Phospholipid Complex with Enhanced Bioavailability and No Food Effect - Yiwen Qian; Guoguang Chen; Jin Wang; Lili Ren (AAPS PharmSciTech, 2018)

Oral Brain-Targeted Microemulsion for Enhanced Piperine Delivery in Alzheimer’s Disease Therapy: In Vitro Appraisal, In Vivo Activity, and Nanotoxicity - Samar M. Etman; Yosra S. R. Elnaggar; Doaa A. Abdelmonsif; Ossama Y. Abdallah (AAPS PharmSciTech, 2018)

Composite Microparticles Based on Natural Mucoadhesive Polymers with Promising Structural Properties to Protect and Improve the Antifungal Activity of Miconazole Nitrate - G. Tejada; M. C. Lamas; M. Sortino; V. A. Alvarez; D. Leonardi (AAPS PharmSciTech, 2018)

Evaluation of Nasal Inlet Ports Having Simplified Geometry for the Pharmacopeial Assessment of Mass Fraction of Dose Likely to Penetrate Beyond the Nasopharynx: a Preliminary Investigation - Gerallt Williams; Chris Blatchford; Jolyon P. Mitchell (AAPS PharmSciTech, 2018)

Development and Characterization of Novel Medicated Nanofiber for the Treatment of Periodontitis - Amar Deepak; Amit K. Goyal; Goutam Rath (AAPS PharmSciTech, 2018)

Optimization and Characterization of Thymoquinone-Loaded Liposomes with Enhanced Topical Anti-inflammatory Activity - Mahmoud Mostafa; Eman Alaaeldin; Usama Farghaly Aly; Hatem A. Sarhan (AAPS PharmSciTech, 2018)

Novel Self-Assembled Ibrutinib-Phospholipid Complex for Potently Peroral Delivery of Poorly Soluble Drugs with pH-Dependent Solubility - Qiujun Qiu; Mei Lu; Cong Li; Xiang Luo; Xinrong Liu; Ling Hu; Mingqi Liu; Huangliang Zheng; Hongxia Zhang; Min Liu; Chaoyang Lai; Yanzhi Song; et al. (AAPS PharmSciTech, 2018)

Lipid Architectonics for Superior Oral Bioavailability of Nelfinavir Mesylate: Comparative in vitro and in vivo Assessment - Tejashree Belubbi; Sukhada Shevade; Vivek Dhawan; Vinay Sridhar; Anuradha Majumdar; Rute Nunes; Francisca Araújo; Bruno Sarmento; Kalpa Nagarsenker; Frank Steiniger; Alfred Fahr; Aniket Magarkar; et al. (AAPS PharmSciTech, 2018)

Colloidally Stable Small Unilamellar Stearyl Amine Lipoplexes for Effective BMP-9 Gene Delivery to Stem Cells for Osteogenic Differentiation - Imran Vhora; Rohan Lalani; Priyanka Bhatt; Sushilkumar Patil; Hinal Patel; Vivek Patel; Ambikanandan Misra (AAPS PharmSciTech, 2018)

PSMA Antibody-Conjugated Pentablock Copolymer Nanomicellar Formulation for Targeted Delivery to Prostate Cancer - Alex Oselu Owiti; Dhananjay Pal; Ashim Mitra (AAPS PharmSciTech, 2018)

Microemulsion and Microporation Effects on the Genistein Permeation Across Dermatomed Human Skin - Li Chen; Manjusha Annaji; Sharmila Kurapati; William R. Ravis; R. Jayachandra Babu (AAPS PharmSciTech, 2018)

Extrusion 3D Printing of Paracetamol Tablets from a Single Formulation with Tunable Release Profiles Through Control of Tablet Geometry - Shaban A. Khaled; Morgan R. Alexander; Derek J. Irvine; Ricky D. Wildman; Martin J. Wallace; Sonja Sharpe; Jae Yoo; Clive J. Roberts (AAPS PharmSciTech, 2018)
An extrusion-based 3D printer was used to fabricate paracetamol tablets with different geometries (mesh, ring and solid) from a single paste-based formulation formed from standard pharmaceutical ingredients. The tablets demonstrate that tunable drug release profiles can be achieved from this single formulation even with high drug loading (> 80% w / w ). The tablets were evaluated for drug release using a USP dissolution testing type I apparatus. The tablets showed well-defined release profiles (from immediate to sustained release) controlled by their different geometries. The dissolution results showed dependency of drug release on the surface area/volume (SA/V) ratio and the SA of the different tablets. The tablets with larger SA/V ratios and SA had faster drug release. The 3D printed tablets were also evaluated for physical and mechanical properties including tablet dimension, drug content, weight variation and breaking force and were within acceptable range as defined by the international standards stated in the US Pharmacopoeia. X-ray powder diffraction, differential scanning calorimetry and attenuated total reflectance Fourier transform infrared spectroscopy were used to identify the physical form of the active and to assess possible drug-excipient interactions. These data again showed that the tablets meet USP requirement. These results clearly demonstrate the potential of 3D printing to create unique pharmaceutical manufacturing, and potentially clinical, opportunities. The ability to use a single unmodified formulation to achieve defined release profiles could allow, for example, relatively straightforward personalization of medicines for individuals with different metabolism rates for certain drugs and hence could offer significant development and clinical opportunities.

Correction to: Effects of Dendrimer-Like Biopolymers on Physical Stability of Amorphous Solid Dispersions and Drug Permeability Across Caco-2 Cell Monolayers - Monika Lavan; Gregory Knipp (AAPS PharmSciTech, 2018)

Pharmaceutical Additive Manufacturing: a Novel Tool for Complex and Personalized Drug Delivery Systems - Jiaxiang Zhang; Anh Q. Vo; Xin Feng; Suresh Bandari; Michael A. Repka (AAPS PharmSciTech, 2018)

The Effect of Inkjet Printing over Polymeric Films as Potential Buccal Biologics Delivery Systems - Miguel Montenegro-Nicolini; Patricio E. Reyes; Miguel O. Jara; Parameswara R. Vuddanda; Andrónico Neira-Carrillo; Nicole Butto; Sitaram Velaga; Javier O. Morales (AAPS PharmSciTech, 2018)

Controlled Release of 5-Fluorouracil from Alginate Beads Encapsulated in 3D Printed pH-Responsive Solid Dosage Forms - Christos I. Gioumouxouzis; Aikaterini-Theodora Chatzitaki; Christina Karavasili; Orestis L. Katsamenis; Dimitrios Tzetzis; Emmanouela Mystiridou; Nikolaos Bouropoulos; Dimitrios G. Fatouros (AAPS PharmSciTech, 2018)

Application of FT-NIR Analysis for In-line and Real-Time Monitoring of Pharmaceutical Hot Melt Extrusion: a Technical Note - Anh Q. Vo; Herman He; Jiaxiang Zhang; Scott Martin; Rui Chen; Michael A. Repka (AAPS PharmSciTech, 2018)

Influence of Geometry on the Drug Release Profiles of Stereolithographic (SLA) 3D-Printed Tablets - Pamela Robles Martinez; Alvaro Goyanes; Abdul W. Basit; Simon Gaisford (AAPS PharmSciTech, 2018)

Industrial Development of a 3D-Printed Nutraceutical Delivery Platform in the Form of a Multicompartment HPC Capsule - Alice Melocchi; Federico Parietti; Simone Maccagnan; Marco Aldo Ortenzi; Stefano Antenucci; Francesco Briatico-Vangosa; Alessandra Maroni; Andrea Gazzaniga; Lucia Zema (AAPS PharmSciTech, 2018)

3D-Printed Network Structures as Controlled-Release Drug Delivery Systems: Dose Adjustment, API Release Analysis and Prediction - Carolin Korte; Julian Quodbach (AAPS PharmSciTech, 2018)

Correction to: First Development, Optimization, and Stability Control of a Pediatric Oral Atenolol Formulation - Mauro Morri; Patricia Castellano; Darío Leonardi; Silvana Vignaduzzo (AAPS PharmSciTech, 2018)

Nucleic Acid-Based Therapeutics for Pulmonary Diseases - Jing Chen; Yue Tang; Yun Liu; Yushun Dou (AAPS PharmSciTech, 2018)

Impact of Natural Variations in Freeze-Drying Parameters on Product Temperature History: Application of Quasi Steady-State Heat and Mass Transfer and Simple Statistics - Michael J. Pikal; Paritosh Pande; Robin Bogner; Pooja Sane; Vamsi Mudhivarthi; Puneet Sharma (AAPS PharmSciTech, 2018)

Scale-Up and In-line Monitoring During Continuous Melt Extrusion of an Amorphous Solid Dispersion - Abbe Haser; Brian Haight; Andreas Berghaus; Augie Machado; Charlie Martin; Feng Zhang (AAPS PharmSciTech, 2018)

Development of Hot Melt Extruded Solid Dispersion of Tamoxifen Citrate and Resveratrol for Synergistic Effects on Breast Cancer Cells - Nusrat Chowdhury; Imran Vhora; Ketan Patel; Arvind Bagde; Shallu Kutlehria; Mandip Singh (AAPS PharmSciTech, 2018)

Comparative Study for Optimization of Pharmaceutical Self-Emulsifying Pre-concentrate by Design of Experiment and Artificial Neural Network - Kinjal J. Parikh; Krutika K. Sawant (AAPS PharmSciTech, 2018)

Impact of Porous Excipients on the Manufacturability and Product Performance of Solid Self-Emulsifying Drug Delivery Systems - André O’Reilly Beringhs; Bruna Cristina Minatovicz; Geoff G. Z. Zhang; Bodhisattwa Chaudhuri; Xiuling Lu (AAPS PharmSciTech, 2018)

Development and Evaluation of Compression Coating Gastro-Floating Tablet of Alfuzosin Hydrochloride for Zero-Order Controlled Release - Ling Gong; Yanyan Sun; Miao Yu; Ying Gao; Meijuan Zou; Gang Cheng (AAPS PharmSciTech, 2018)

Thermal Magnetic Field Activated Propolis Release From Liquid Crystalline System Based on Magnetic Nanoparticles - Lucas de Alcântara Sica de Toledo; Hélen Cássia Rosseto; Rafaela Said dos Santos; Federico Spizzo; Lucia Del Bianco; Maiara Camotti Montanha; Elisabetta Esposito; Elza Kimura; Patricia de Souza Bonfim-Mendonça; Terezinha Inez Estivalet Svidzinski; Rita Cortesi; Marcos Luciano Bruschi (AAPS PharmSciTech, 2018)

Using pH Gradient Dissolution with In-Situ Flux Measurement to Evaluate Bioavailability and DDI for Formulated Poorly Soluble Drug Products - Jane Li; Konstantin Tsinman; Oksana Tsinman; Larry Wigman (AAPS PharmSciTech, 2018)

A Simple and Rapid Method for Deposition and Measurement of Drug Transport Across Air Interface Respiratory Epithelia - Mehra Haghi; Paul M Young; Daniela Traini (AAPS PharmSciTech, 2018)

Simultaneously Improving Mechanical, Formulation, and In Vivo Performance of Naproxen by Co-Crystallization - Nasir Abbas; Sumera Latif; Hafsa Afzal; Muhammad Sohail Arshad; Amjad Hussain; Saleha Sadeeqa; Nadeem Irfan Bukhari (AAPS PharmSciTech, 2018)

Smartly Engineered PEGylated Di-Block Nanopolymeric Micelles: Duo Delivery of Isoniazid and Rifampicin Against Mycobacterium tuberculosis - Sarita Rani; Avinash Gothwal; Iliyas Khan; Praveen K. Pachouri; N. Bhaskar; Umesh D. Gupta; Devendra S. Chauhan; Umesh Gupta (AAPS PharmSciTech, 2018)

Sensitive Determination of Fentanyl in Low-Volume Serum Samples by LC-MS/MS - Suresh Kumar Swaminathan; James Fisher; Karunya K. Kandimalla (AAPS PharmSciTech, 2018)

Preparation of a Mesoporous Structure of SnO2 for Increasing the Oral Bioavailability and Dissolution Rate of Nitrendipine - Xuan Liu; Chao Wu; Andi Bai; Huiling Lv; Xiaoyan Xu; Yue Cao; Wenjing Shang; Lili Hu; Ying Liu (AAPS PharmSciTech, 2018)

Third-Generation Transdermal Delivery Systems Containing Zidovudine: Effect of the Combination of Different Chemical Enhancers and a Microemulsion System - André Luis Menezes Carvalho; José Alexsandro Silva; Ana Amélia Moreira Lira; Ellen Denise Prado Almeida; Rogéria de Souza Nunes; Victor Hugo Vitorino Sarmento; Leiz Maria Costa Veras; José Roberto de Almeida Leite; Leila Bastos Leal; Davi Pereira de Santana (AAPS PharmSciTech, 2018)

Evaluating the Accelerated Blood Clearance Phenomenon of PEGylated Nanoemulsions in Rats by Intraperitoneal Administration - Yuqing Su; Mengyang Liu; Kaifan Liang; Xinrong Liu; Yanzhi Song; Yihui Deng (AAPS PharmSciTech, 2018)

Preparation and Evaluation of Skin Wound Healing Chitosan-Based Hydrogel Membranes - Sarfaraz Ahmad; Muhammad Usman Minhas; Mahmood Ahmad; Muhammad Sohail; Orva Abdullah; Syed Faisal Badshah (AAPS PharmSciTech, 2018)

Physiological Considerations and In Vitro Strategies for Evaluating the Influence of Food on Drug Release from Extended-Release Formulations - Mirko Koziolek; Edmund Kostewicz; Maria Vertzoni (AAPS PharmSciTech, 2018)

The Influence of Simulated Fasted Gastrointestinal pH Profiles on Diclofenac Sodium Dissolution in a Glass-Bead Flow-Through System - Tjaša Felicijan; Mitja Pišlar; Kaja Vene; Marija Bogataj (AAPS PharmSciTech, 2018)

Preclinical Explorative Assessment of Celecoxib-Based Biocompatible Lipidic Nanocarriers for the Management of CFA-Induced Rheumatoid Arthritis in Wistar Rats - Pradip Nirbhavane; Gajanand Sharma; Bhupinder Singh; Gopal K Khuller; Vijay G Goni; A. B. Patil; Om Prakash Katare (AAPS PharmSciTech, 2018)

The Impact of the National Institute for Pharmaceutical Technology and Education on Academic Research - Marilyn K. Speedie (AAPS PharmSciTech, 2018)

Development and Characterisation of Modified Release Hard Gelatin Capsules, Based on In Situ Lipid Matrix Formation - Gábor Vasvári; Bence Csontos; Tamás Sovány; Géza Regdon; Attila Bényei; Judit Váradi; Ildikó Bácskay; Zoltán Ujhelyi; Pálma Fehér; Dávid Sinka; Thi Le Phuong Nguyen; Miklós Vecsernyés; et al. (AAPS PharmSciTech, 2018)

Amphotericin B Loaded Chitosan Nanoparticles: Implication of Bile Salt Stabilization on Gastrointestinal Stability, Permeability and Oral Bioavailability - Sanyog Jain; Chamala Siva Kumar Reddy; Rajan Swami; Varun Kushwah (AAPS PharmSciTech, 2018)

In Vivo Determination of Moisturizers Efficacy on Human Skin Hydration by Confocal Raman Spectroscopy - Vamshi Krishna Tippavajhala; Taciana D. Magrini; Daniele C. Matsuo; Michely G. P. Silva; Priscila P. Favero; Leonardo Rodrigues De Paula; Airton Abrahão Martin (AAPS PharmSciTech, 2018)

Evaluation of Anti-Tumor Efficacy of Vorinostat Encapsulated Self-Assembled Polymeric Micelles in Solid Tumors - Sri Vishnu Kiran Rompicharla; Prakruti Trivedi; Preeti Kumari; Omkara Swami Muddineti; Sowmya Theegalapalli; Balaram Ghosh; Swati Biswas (AAPS PharmSciTech, 2018)

European Regulatory Developments for Orally Inhaled and Nasal Drug Products - Carlos Santos; Gustavo Marco; Lee M. Nagao; Eva Castro; Tim Chesworth (AAPS PharmSciTech, 2018)

Using Manufacturing Design Space Concepts for Stability Risk Assessment—Gabapentin NIPTE/FDA Case Study - Stephen D. Stamatis; Lee E. Kirsch (AAPS PharmSciTech, 2018)

The Effects of Fillers and Binders on the Accuracy of Tablet Subdivision - Gessyka Rayana S. Pereira; Stephania F. Taveira; Marcilio Cunha-Filho; Ricardo Neves Marreto (AAPS PharmSciTech, 2018)

Apoptosis Induction and Antimigratory Activity of Andrographolide Analog (3A.1)-Incorporated Self-Assembled Nanoparticles in Cancer Cells - Teeratas Kansom; Warayuth Sajomsang; Rungnapha Saeeng; Purin Charoensuksai; Praneet Opanasopit; Prasopchai Tonglairoum (AAPS PharmSciTech, 2018)

Particle Size Distribution Equivalency as Novel Predictors for Bioequivalence - Pratak Ngeacharernkul; Stephen D. Stamatis; Lee E. Kirsch (AAPS PharmSciTech, 2018)

Strategic Pentablock Copolymer Nanomicellar Formulation for Paclitaxel Delivery System - Alex Oselu Owiti; Ashim Mitra; Mary Joseph; Dhananjay Pal (AAPS PharmSciTech, 2018)

Solid Form of Lipid-Based Self-Nanoemulsifying Drug Delivery Systems for Minimization of Diacerein Adverse Effects: Development and Bioequivalence Evaluation in Albino Rabbits - Mohamed Ahmed Naseef; Howida Kamal Ibrahim; Samia Abd El-Kader Nour (AAPS PharmSciTech, 2018)

Optimization of Ciprofloxacin Hydrochloride Spray-Dried Microparticles for Pulmonary Delivery Using Design of Experiments - Mariela Razuc; Juliana Piña; María V. Ramírez-Rigo (AAPS PharmSciTech, 2018)

Lacidipine Amorphous Solid Dispersion Based on Hot Melt Extrusion: Good Miscibility, Enhanced Dissolution, and Favorable Stability - Long Xi; Hang Song; Yunzhi Wang; Haoshi Gao; Qiang Fu (AAPS PharmSciTech, 2018)

Preparation of Sustained Release Tablet with Minimized Usage of Glyceryl Behenate Using Post-Heating Method - Changmin Kang; Ju-Hyun Lee; Dong-Wook Kim; Beom-Jin Lee; Jun-Bom Park (AAPS PharmSciTech, 2018)

Preparation, Characterization and Pharmacokinetics Evaluation of the Compound Capsules of Ibuprofen Enteric-Coated Sustained-Release Pellets and Codeine Phosphate Immediate-Release Pellets - Ling Dong; Feifei Yang; Zhihong Zhu; Yue Yang; Xiaoyu Zhang; Mingzhu Ye; Weisan Pan; Hao Pan (AAPS PharmSciTech, 2018)

Research Progress of Raman Spectroscopy in Drug Analysis - Wen-ting Wang; Hua Zhang; Yuan Yuan; Ya Guo; Shi-xin He (AAPS PharmSciTech, 2018)

Characterization of Inclusion Complex of Coenzyme Q10 with the New Carrier CD-MOF-1 Prepared by Solvent Evaporation - Yutaka Inoue; Ayumi Nanri; Isamu Murata; Ikuo Kanamoto (AAPS PharmSciTech, 2018)

Medicated Chewing Gums (MCGs): Composition, Production, and Mechanical Testing - Turki Al Hagbani; Sami Nazzal (AAPS PharmSciTech, 2018)

Skin Permeation and Oxidative Protection Effect of Soybean Isoflavones from Topical Nanoemulsions—a Comparative Study of Extracts and Pure Compounds - Patricia Inês Back; Luisa Rodrigues Furtado; Marina Cardoso Nemitz; Lucélia Albarello Balestrin; Flávia Nathiely Silveira Fachel; Henrique Mautone Gomes; Roselena Silvestri Schuh; José Cláudio Moreira; Gilsane Lino von Poser; Helder Ferreira Teixeira (AAPS PharmSciTech, 2018)

Effect of the Interaction Between an Ionic Surfactant and Polymer on the Dissolution of a Poorly Soluble Drug - Vaishnavi Parikh; Suhas G. Gumaste; Shivaji Phadke (AAPS PharmSciTech, 2018)

The Sensitivity of In Vitro Permeation Tests to Chemical Penetration Enhancer Concentration Changes in Fentanyl Transdermal Delivery Systems - Soo Hyeon Shin; Jukkarin Srivilai; Sarah A. Ibrahim; Caroline Strasinger; Dana C. Hammell; Hazem E. Hassan; Audra L. Stinchcomb (AAPS PharmSciTech, 2018)

Morphological, Stability, and Hypoglycemic Effects of New Gliclazide-Bile Acid Microcapsules for Type 1 Diabetes Treatment: the Microencapsulation of Anti-diabetics Using a Microcapsule-Stabilizing Bile Acid - Sangeetha Mathavan; Nigel Chen-Tan; Frank Arfuso; Hani Al-Salami (AAPS PharmSciTech, 2018)

Polymorphic and Quantum Chemistry Characterization of Candesartan Cilexetil: Importance for the Correct Drug Classification According to Biopharmaceutics Classification System - Débora Priscila de Campos; Neila Márcia Silva-Barcellos; Renata Rodrigues Lima; Ranylson Marcello Leal Savedra; Melissa Fabíola Siqueira; Maria Irene Yoshida; Wagner da Nova Mussel; Jacqueline de Souza (AAPS PharmSciTech, 2018)

Preparation and Characterization of Tetrahydrocurcumin-Loaded Cellulose Acetate Phthalate/Polyethylene Glycol Electrospun Nanofibers - Ravikumar Rramaswamy; Ganesh Mani; Senthil Venkatachalam; Ramesh Venkata Yasam; J. C. Bose Rajendran; Jang Hyun Tae (AAPS PharmSciTech, 2018)

Tablet Formulation of a Polymeric Solid Dispersion Containing Amorphous Alkalinized Telmisartan - Jun Soo Chae; Bo Ram Chae; Dong Jun Shin; Yoon Tae Goo; Eun Seok Lee; Ho Yub Yoon; Chang Hyun Kim; Young Wook Choi (AAPS PharmSciTech, 2018)

Development and Evaluation of Stimuli-Responsive Chimeric Nanostructures - Nikolaos Naziris; Natassa Pippa; Dimitris Stellas; Varvara Chrysostomou; Stergios Pispas; Costas Demetzos; Marcin Libera; Barbara Trzebicka (AAPS PharmSciTech, 2018)

Labrasol-Enriched Nanoliposomal Formulation: Novel Approach to Improve Oral Absorption of Water-Insoluble Drug, Carvedilol - Samaneh Ghassemi; Azadeh Haeri; Soraya Shahhosseini; Simin Dadashzadeh (AAPS PharmSciTech, 2018)

Glibenclamide Mini-tablets with an Enhanced Pharmacokinetic and Pharmacodynamic Performance - Hesham M. Tawfeek; Matthew Roberts; Mohamed A. El Hamd; Ahmed A. H. Abdellatif; Mahmoud A. Younis (AAPS PharmSciTech, 2018)

Effect of Arginine on the Aggregation of Protein in Freeze-Dried Formulations Containing Sugars and Polyol: II. BSA Reconstitution and Aggregation - Ellen Hackl; Joseph Darkwah; Geoff Smith; Irina Ermolina (AAPS PharmSciTech, 2018)

New Approach for the Application of USP Apparatus 3 in Dissolution Tests: Case Studies of Three Antihypertensive Immediate-Release Tablets - Brenda Espíndola; Francieli Furlan Bortolon; Juliana Munari Oliveira Pinto; Bianca Ramos Pezzini; Hellen Karine Stulzer (AAPS PharmSciTech, 2018)

A Simplified Geometric Model to Predict Nasal Spray Deposition in Children and Adults - Mow Yee Foo; Namita Sawant; Ellen Overholtzer; Maureen D. Donovan (AAPS PharmSciTech, 2018)

A Modified In Situ Method to Determine Release from a Complex Drug Carrier in Particle-Rich Suspensions - Caroline Alvebratt; Ocean Cheung; Maria Strømme; Christel A. S. Bergström (AAPS PharmSciTech, 2018)

Physiologically Based Absorption Modeling of Salts of Weak Bases Based on Data in Hypochlorhydric and Achlorhydric Biorelevant Media - Filippos Kesisoglou; Maria Vertzoni; Christos Reppas (AAPS PharmSciTech, 2018)

Influence of Postprandial Intragastric Pressures on Drug Release from Gastroretentive Dosage Forms - Felix Schneider; Melanie Hoppe; Mirko Koziolek; Werner Weitschies (AAPS PharmSciTech, 2018)

Correction to: Preparation of Controlled-Release Particles Based on Spherical Porous Silica Used as the Drug Carrier by the Dry Coating Method - Shohei Nakamura; Shihoko Kondo; Ayaka Mohri; Takatoshi Sakamoto; Hiroshi Yuasa (AAPS PharmSciTech, 2018)

Influence of Formulation Factors on the Aerosol Performance and Stability of Lysozyme Powders: a Systematic Approach - Silvia Ferrati; Tian Wu; Omar Fuentes; Ashlee D. Brunaugh; Sekhar R. Kanapuram; Hugh D. C. Smyth (AAPS PharmSciTech, 2018)

Correction to: Promising Antibacterial Effects of Silver Nanoparticle-Loaded Tea Tree Oil Nanoemulsion: a Synergistic Combination Against Resistance Threat - Roqya Najafi-taher; Behnaz Ghaemi; Sharmin Kharrazi; Samira Rasoulikoohi; Amir Amani (AAPS PharmSciTech, 2018)

Dry Formulations Enhanced Mucoadhesive Properties and Reduced Cold Chain Handing of Influenza Vaccines - Nattika Saengkrit; Somsak Saesoo; Noppawan Woramongkolchai; Warayuth Sajomsang; Sarunya Phunpee; Tararaj Dharakul; Uracha Rungsardthong Ruktanonchai (AAPS PharmSciTech, 2018)

Correction to: Preparation and Optimization of Fast-Disintegrating Tablet Containing Naratriptan Hydrochloride Using D-Optimal Mixture Design - Samia M. Omar; Fathy I. AbdAlla; Noha M. Abdelgawad (AAPS PharmSciTech, 2018)

The Effects of Curing and Casting Methods on the Physicochemical Properties of Polymer Films - Yingjian Li; Dale Eric Wurster (AAPS PharmSciTech, 2018)

Hydroxypropyl-β-Cyclodextrin and β-Cyclodextrin as Tablet Fillers for Direct Compression - Jaime Conceição; Oluwatomide Adeoye; Helena Maria Cabral-Marques; José Manuel Sousa Lobo (AAPS PharmSciTech, 2018)

Pluronic-Based Mixed Polymeric Micelles Enhance the Therapeutic Potential of Curcumin - Muhammad Usman Akbar; Khalid Mahmood Zia; Ahsan Nazir; Jamshed Iqbal; Syeda Abida Ejaz; Muhammad Sajid Hamid Akash (AAPS PharmSciTech, 2018)

Development and Characterization of Dapsone Cocrystal Prepared by Scalable Production Methods - Lilian Henriques do Amaral; Flavia Almada do Carmo; Maria Inês Amaro; Valeria Pereira de Sousa; Luiz Claudio Rodrigues Pereira da Silva; Gabriella Silva de Almeida; Carlos Rangel Rodrigues; Anne Marie Healy; Lucio Mendes Cabral (AAPS PharmSciTech, 2018)

Chronotherapeutic Drug Delivery of Ketoprofen and Ibuprofen for Improved Treatment of Early Morning Stiffness in Arthritis Using Hot-Melt Extrusion Technology - Nagi Reddy Dumpa; Sandeep Sarabu; Suresh Bandari; Feng Zhang; Michael A. Repka (AAPS PharmSciTech, 2018)

Amisulpride–CD-Loaded Liposomes: Optimization and In Vivo Evaluation - Marwa H. Shukr; Omar A. Ahmed Farid (AAPS PharmSciTech, 2018)

Nanoemulsion-Loaded Hydrogels for Topical Administration of Pentyl Gallate - Regina G. Kelmann; Mariana Colombo; Ricardo J. Nunes; Cláudia M. O. Simões; Letícia S. Koester (AAPS PharmSciTech, 2018)

Authorized Generic Drugs: an Overview - Z. Gulsen Oner; James E. Polli (AAPS PharmSciTech, 2018)

Thermal Behavior of 19F Nuclear Magnetic Resonance Signal of 19F-Containing Compound in Lipid Nano-Emulsion for Potential Tumor Diagnosis - Risa Iima; Shigehiko Takegami; Atsuko Konishi; Shiori Tajima; Nao Minematsu; Tatsuya Kitade (AAPS PharmSciTech, 2018)

Co-Processed Excipients for Dispersible Tablets—Part 2: Patient Acceptability - Karolina Dziemidowicz; Felipe L. Lopez; Ben J. Bowles; Andrew J. Edwards; Terry B. Ernest; Mine Orlu; Catherine Tuleu (AAPS PharmSciTech, 2018)

Novel Extended-Release Multiple-Unit System of Imidafenacin Prepared by Fluid-Bed Coating Technique - Taek Hwan Shin; Sung Hyun Im; Min Su Goh; Eun Seok Lee; Myoung Jin Ho; Chang Hyun Kim; Myung Joo Kang; Young Wook Choi (AAPS PharmSciTech, 2018)