Instructions for Authors (Familial Cancer, 2005)

Molecular pathogenesis of MEN2-associated tumors - Christian A. Koch (Familial Cancer, 2005)

Paragangliomas of the head and neck: diagnosis and treatment - C. C. Boedeker; G. J. Ridder; J. Schipper (Familial Cancer, 2005)

Genetic factors and colorectal cancer in Ashkenazi Jews - Gershon Y. Locker; Henry T. Lynch (Familial Cancer, 2004)

The Jewish people: their ethnic history, genetic disorders and specific cancer susceptibility - Inbal Kedar-Barnes; Paul Rozen (Familial Cancer, 2004)

Cancer in Jews: introduction and overview - Henry T. Lynch; Wendy S. Rubinstein; Gershon Y. Locker (Familial Cancer, 2004)

Abstracts of the ESO Inside Track Conference on Familial Cancer, CNIO, Madrid, Spain, 6–7 May 2004 (Familial Cancer, 2004)

Genotyping Possible Polymorphic Variants of Human Mismatch Repair Genes in Healthy Korean Individuals and Sporadic Colorectal Cancer Patients - Jin C. Kim; Seon A. Roh; Kum H. Koo; In H. Ka; Hee C. Kim; Chang S. Yu; Kang H. Lee; Jung S. Kim; Han I. Lee; Walter F. Bodmer (Familial Cancer, 2004)

Prognosis in DNA Mismatch Repair Deficient Colorectal Cancer: are all MSI Tumours Equivalent? - A. J. Clark; R. Barnetson; S. M. Farrington; M. G. Dunlop (Familial Cancer, 2004)

Sporadic Versus Hereditary forms of Colorectal Cancer with the DNA Microsatellite Instability Phenotype: to ‘lump’ or ‘Split’? - Jeremy R. Jass (Familial Cancer, 2004)

A Homozygous MSH6 Mutation in a Child with Café-au-Lait Spots, Oligodendroglioma and Rectal Cancer - Fred H. Menko; Gertjan L. Kaspers; Gerrit A. Meijer; Kathleen Claes; Johanna M. van Hagen; Johan J. P. Gille (Familial Cancer, 2004)

Abstracts Presented at the XVIIth Symposium ‘New Developments in Hereditary Cancer’, 5–6 February 2004, Amsterdam, the Netherlands (Familial Cancer, 2004)

Impact of a Cancer Registry-Based Genealogy Service to Support Clinical Genetics Services - David H. Brewster; Alison Fordyce; Roger J. Black (Familial Cancer, 2004)

Correlations between Phenotype and Microsatellite Instability in HNPCC: Implications for Genetic Testing - Raffaele Palmirotta; Sabino Matera; Maria Cristina Curia; Gitana Aceto; Bassam el Zhobi; Fabio Verginelli; Fiorella Guadagni; Vincenzo Casale; Vittoria Stigliano; Luca Messerini; Renato Mariani-Costantini; Pasquale Battista; et al. (Familial Cancer, 2004)

Evaluation of Psychosocial Effects of Pre-Symptomatic Testing for Breast/Ovarian and Colon Cancer Pre-Disposing Genes: A 12-Month Follow-Up - Brita Arver; Aina Haegermark; Ulla Platten; Annika Lindblom; Yvonne Brandberg (Familial Cancer, 2004)

Promoter Hypermethylation Frequency and BRAF Mutations Distinguish Hereditary Non-Polyposis Colon Cancer from Sporadic MSI-H Colon Cancer - A. McGivern; C.V.A. Wynter; V.L.J. Whitehall; T. Kambara; K.J. Spring; M.D. Walsh; M.A. Barker; S. Arnold; L.A. Simms; B.A. Leggett; J. Young; J.R. Jass (Familial Cancer, 2004)

HNPCC and Sporadic MSI-H Colorectal Cancer: A Review of the Morphological Similarities and Differences - Jeremy R. Jass (Familial Cancer, 2004)

Instructions for authors (Familial Cancer, 2004)

Delivering Information about Cancer Genetics via Letter to Patients at Low and Moderate Risk of Familial Cancer: A Pilot Study in Wales - C. Phelps; K. Platt; L. France; J. Gray; R. Iredale (Familial Cancer, 2004)

The 1100delAT BRCA1 and the 8765delAG BRCA2 Mutations: Occurrence in High-Risk Non-Ashkenazi Jews and Haplotype Comparison of Jewish and Non-Jewish Carriers - Inbar Gal; Ruth Gershoni Baruch; Daniel Haber; Efrat Dagan; Shlomit Eisenberg-Barzilai; Jamal Zidan; Eitan Friedman (Familial Cancer, 2004)

Familial Cancer 2003 – Research and Practice, Couran Cove, Queensland, Australia, 3–6 September 2003 - Geoffrey J. Lindeman (Familial Cancer, 2004)

Intron 4 Mutation in APC Gene Results in Splice Defect and Attenuated FAP Phenotype - Deborah W. Neklason; Cindy H. Solomon; Amy L. Dalton; Scott K. Kuwada; Randall W. Burt (Familial Cancer, 2004)

Familial Pancreatic Cancer - Harald Rieder; Detlef K. Bartsch (Familial Cancer, 2004)

BRCA1 testing with definitive results: a prospective study of psychological distress in a large clinic-based sample - Jon G. Reichelt; Ketil Heimdal; Pål Møller; Alv A. Dahl (Familial Cancer, 2004)

BRCA1 testing in breast and/or ovarian cancer families from northeastern France identifies two common mutations with a founder effect - Danièle Muller; Catherine Bonaiti-Pelié; Joseph Abecassis; Dominique Stoppa-Lyonnet; Jean-Pierre Fricker (Familial Cancer, 2004)

An audit of screening for familial breast cancer before 50 years in the South Thames Region – have we got it right? - Victoria Murday; R. Pears; J. Ball; R. Eeles; S. Hodgson (Familial Cancer, 2004)

Cancer variation associated with the position of the mutation in the BRCA2 gene - Jan Lubinski; Catherine M. Phelan; Parviz Ghadirian; Henry T. Lynch; Judy Garber; Barbara Weber; Nadine Tung; Douglas Horsman; Claudine Isaacs; Alvaro N. A. Monteiro; Ping Sun; Steven A. Narod (Familial Cancer, 2004)

Patients' and professionals' opinions of services for people at an increased risk of colorectal cancer: an exploratory qualitative study - Tamar Stermer; Shirley Hodgson; Fred Kavalier; Sally Watts; Roger Jones (Familial Cancer, 2004)

Health economics and genetic service development: a familial cancer genetic example - David Cohen; Garry Barton; Jonathon Gray; Kate Brain (Familial Cancer, 2004)

Frequency of extra-colonic tumors in hereditary nonpolyposis colorectal cancer (HNPCC) and familial colorectal cancer (FCC) Brazilian families: An analysis by a Brazilian Hereditary Colorectal Cancer Institutional Registry - Fáblio Oliveira Ferreira; Claudia Cristina Napoli Ferreira; Benedito Mauro Rossi; Wilson Toshihiko Nakagawa; Samuel Aguilar; Erika Maria Monteiro Santos; Marcelo Leite Vierira Costa; Ademar Lopes (Familial Cancer, 2004)

Fanconi anemia in Ashkenazi Jews - David I. Kutler; Arleen D. Auerbach (Familial Cancer, 2004)

Hereditary ovarian cancer in Ashkenazi Jews - Luis Robles-daz; Deborah J Goldfrank; Noah D Kauff; Mark Robson; Kenneth Offit (Familial Cancer, 2004)

Familial pancreatic carcinoma in Jews - Henry T Lynch; Carolyn A Deters; Jane F Lynch; Randall E Brand (Familial Cancer, 2004)

Inflammatory bowel disease in Ashkenazi Jews: implications for familial colorectal cancer - T. Lynch Henry; E. Brand Randall; Y. Locker Gershon (Familial Cancer, 2004)

Acknowledgements (Familial Cancer, 2004)

A636P testing in Ashkenazi Jews - G. guillem Jose; G. moore Harvey; Palmer Crystal; Glogowski Emily; Rob Finch; Nafa Khedoudja; J. Markowitz Arnold; Offit Kenneth; A. Ellis Nathan (Familial Cancer, 2004)

Key word index Volume 3 (Familial Cancer, 2004)

Volume Contents (Familial Cancer, 2004)

Peritoneal carcinoma in women with genetic susceptibility: implications for Jewish populations - Murray Joseph Casey; Chhanda Bewtra (Familial Cancer, 2004)

Hereditary breast cancer in Jews - Wendy S. Rubinstein (Familial Cancer, 2004)

Trends in colorectal cancer incidence and mortality in the Israeli Jewish ethnic populations - Micha Barchana; Irena Liphshitz; Paul Rozen (Familial Cancer, 2004)

Ashkenazi Jewish genetic disorders - Joel Charrow (Familial Cancer, 2004)

Foreword - Steven M. Lipkin (Familial Cancer, 2004)

Abstracts presented at the Breast Cancer Linkage Consortium (BCLC) and the International Collaborative Group on Familial Breast and Ovarian Cancer (ICG-FBOC) 14th General Meeting at the Centro Nacional de Investigaciones Oncológica (CNIO), Madrid, Spain, 2–4 June 2003 Abstracts/posters (Familial Cancer, 2003)

Abstracts presented at the Breast Cancer Linkage Consortium (BCLC) and the International Collaborative Group on Familial Breast and Ovarian Cancer (ICG-FBOC) 14th General Meeting at the Centro Nacional de Investigaciones Oncológica (CNIO), Madrid, Spain, 2–4 June 2003 Abstracts/sessions (Familial Cancer, 2003)

Are there socio-economic inequalities in age of resection of colorectal cancer in people with HNPCC? - Jean Adams; Martin White; Gail Barker; John Mathers; John Burn (Familial Cancer, 2003)

What motivates interest in attending a familial cancer genetics clinic? - L. Fraser; S. Bramald; C. Chapman; C. Chu; V. Cornelius; F. Douglas; A. Lucassen; A. Nehammer; S. Sutton; M. Trivella; S. Hodgson (Familial Cancer, 2003)

Swiss primary care physicians' knowledge, attitudes and perception towards genetic testing for hereditary breast cancer - Gabriella Pichert; Daniel Dietrich; Peter Moosmann; Marcel Zwahlen; Rolf Arno Stahel; André-Pascal Sappino (Familial Cancer, 2003)

Abstracts presented at the XVIth symposium of The Netherlands Foundation for the Detection of Hereditary Tumours, 'New Developments in Hereditary Cancer', 31 January 2003, Utrecht, The Netherlands (Familial Cancer, 2003)

Lack of association between early onset of breast cancer and numbers of affected relatives in an Iranian population - M. Atri; E. Jafarimojarrad; M. Javidroozi; P. Mehdipour (Familial Cancer, 2003)

Genotype and phenotype of patients with both familial adenomatous polyposis and thyroid carcinoma - Brindusa Truta; Brian A. Allen; Peggy G. Conrad; Young S. Kim; Terri Berk; Steven Gallinger; Bharati Bapat; Jonathan P. Terdiman; Marvin H. Sleisenger (Familial Cancer, 2003)

Familial melanoma: a complex disorder leading to controversy on DNA testing - Femke A. de Snoo; Wilma Bergman; Nelleke A. Gruis (Familial Cancer, 2003)

Abstracts presented at the Spring Conference 2003 of the Cancer Genetics Group, 12–13 May 2003, Southampton, UK (Familial Cancer, 2003)

Spouse controls in family case-control studies: a methodological consideration - Bas A. J. Verhage; Katja K. H. Aben; Huub Straatman; André L. M. Verbeek; Terri H. Beaty; Lambertus A. Kiemeney (Familial Cancer, 2003)

Family history of colorectal cancer in a Sweden county - Louise Olsson; Annika Lindblom (Familial Cancer, 2003)

Erratum (Familial Cancer, 2003)

Bannayan–Riley–Ruvalcaba syndrome: further delineation of the phenotype and management of PTEN mutation-positive cases - Y.M.C. Hendriks; J.T.C.M. Verhallen; J.J. van der Smagt; S.G. Kant; Y. Hilhorst; L. Hoefsloot; K.B.-M. Hansson; P.J.C. van der Straaten; H. Boutkan; M.H. Breuning; H.F.A. Vasen; A.H.J.T. Bröcker-Vriends (Familial Cancer, 2003)

The information and support needs of women at high risk of familial breast and ovarian cancer: how can cancer genetic services give patients what they want? - Rachel Iredale; Kate Brain; Liz Edwards; Jonathon Gray; Elizabeth France (Familial Cancer, 2003)

Histopathological characteristics of BRCA1- and BRCA2-associated intraperitoneal cancer: a clinic-based study - Jurgen M. J. Piek; Bas Torrenga; Brenda Hermsen; René H. M. Verheijen; Ronald P. Zweemer; Johan J. P. Gille; Peter Kenemans; Paul J. van Diest; Fred H. Menko (Familial Cancer, 2003)

The inframe MSH2 codon 596 deletion is linked with HNPCC and associated with lack of MSH2 protein in tumours - Astrid T. Stormorken; Wolfram Müller; Annika Lindblom; Ketil Heimdal; Steinar Aase; Inger Marie Bowitz Lothe; Tove Norèn; Juul T. Wijnen; Gabriela Möslein; Pål Møller (Familial Cancer, 2003)

Genetic susceptibility to prostate cancer: a review - Bas A. J. Verhage; Lambertus A. L. M. Kiemeney (Familial Cancer, 2003)

Attenuated familial adenomatous polyposis (AFAP): a review of the literature - Anne Lyster Knudsen; Marie Luise Bisgaard; Steffen Bülow (Familial Cancer, 2003)

Does the occurrence of certain rare cancers indicate an inherited cancer susceptibility? - Sara Levene; Gillian Scott; Patricia Price; Jeremy Sanderson; Helen Evans; Claire Taylor; Sylvia Bass; Cathryn Lewis; Shirley Hodgson (Familial Cancer, 2003)

Quality of life in patients with multiple endocrine neoplasia type 1 (MEN1) - G. Berglund; A. Lidén; M. G. Hansson; K. Öberg; P. O. Sjöden; K. Nordin (Familial Cancer, 2003)

Instructions for authors (Familial Cancer, 2003)

An audit of familial juvenile polyposis at the Tel Aviv Medical Center: demographic, genetic and clinical features - Paul Rozen; Ziona Samuel; Eli Brazowski; Markus Jakubowicz; Jacob Rattan; Zamir Halpern (Familial Cancer, 2003)

The effect of disease penetrance, family size, and age of onset on family history with application to setting eligibility criteria for genetic testing - Alexandre Sibert; David E. Goldgar (Familial Cancer, 2003)

Origins of the Leeds Castle Polyposis Group - Kay Neale; Steffen Bulow (Familial Cancer, 2003)

Free Paper (Familial Cancer, 2003)

Author index (Familial Cancer, 2003)

History of the International Collaborative Group on Hereditary NonPolyposis Colorectal Cancer - Henry T. Lynch; Giuseppe Cristofaro; Paul Rozen; Hans Vasen; Patrick Lynch; J.-P. Mecklin; Jim St. John (Familial Cancer, 2003)

Program (Familial Cancer, 2003)

Knowledge about breast cancer risk factors and hereditary breast cancer among early-onset breast cancer survivors - Susan Miesfeldt; Wendy Cohn; Mary Ropka; Susan Jones (Familial Cancer, 2001)

Cancer prone persons. A randomized screening trial based on colonoscopy: background, design and recruitment - François Eisinger; Jean-Pierre Giordanella; Alain Brigand; Remi Didelot; Dominique Jacques; Gerard Schenowitz; Claire Julian-Reynier; Jean-François Seitz; Hagay Sobol; Jean Faivre; Hubert Allemand (Familial Cancer, 2001)

Abstracts presented at the XVth Symposium of the NetherlandsFoundation for the Detection of Hereditary Tumours,1 February 2002, Utrecht, The Netherlands (Familial Cancer, 2001)

Prophylactic oophorectomy in Ontario - L. Elit; B. Rosen; V. Goel; L. McLaughlin; M. K. F. Fung; J. Shime; S. Narod (Familial Cancer, 2001)

Instructions-for-authors (Familial Cancer, 2001)

High detection rate for BRCA2 mutations in male breast cancer families from North West England - D. G. R. Evans; M. Bulman; K. Young; D. Gokhale; F. Lalloo (Familial Cancer, 2001)

Keyword index, Volume 1 (Familial Cancer, 2001)

Acknowledgements (Familial Cancer, 2001)

Abstracts presented at the Cancer Genetics Group Meeting,13–14 May 2002, Manchester, UK (Familial Cancer, 2001)

Prediction of the outcome of genetic testing in HNPCC kindreds using the revised Amsterdam criteria and immunohistochemistry - Astrid T. Stormorken; Wolfram Müller; Britta Lemkemeyer; Jaran Apold; Juul T. Wijnen; Riccardo Fodde; Gabriela Möslein; Pål Møller (Familial Cancer, 2001)

Jan Peutz, Harold Jeghers and a remarkable combination of polyposis and pigmentation of the skin and mucous membranes - Josbert J. Keller; G. Johan A. Offerhaus; Francis M. Giardiello; Fred H. Menko (Familial Cancer, 2001)

MRI screening for breast cancer in women with familial or genetic predisposition: design of the Dutch National Study (MRISC) - M. Kriege; C. T. M. Brekelmans; C. Boetes; E. J. T. Rutgers; J. C. Oosterwijk; R. A. E. M. Tollenaar; R. A. Manoliu; R. Holland; H. J. de Koning; J. G. M. Klijn (Familial Cancer, 2001)

Risk models used to counsel women for breast and ovarian cancer: a guide for clinicians - Elizabeth B. Claus (Familial Cancer, 2001)

Comment on Elit et al.: Prophylactic oophorectomy in Ontario - R. P. Zweemer; I. J. Jacobs (Familial Cancer, 2001)

Quality of life and psychosexual adjustment after prophylactic oophorectomy for a family history of ovarian cancer - L. Elit; M.J. Esplen; K. Butler; S. Narod (Familial Cancer, 2001)

Contents of Volume 1 (Familial Cancer, 2001)

Comparison of physicians' and cancer prone women's attitudes about breast/ovarian prophylactic surgery. Results from two national surveys - François Eisinger; Dominique Stoppa-Lyonnet; Christine Lasset; Philippe Vennin; Françoise Chabal; Catherine Noguès; J. P. Moatti; Hagay Sobol; Claire Julian-Reynier (Familial Cancer, 2001)

Apparent Mendelian inheritance of breast and colorectal cancer: chance, genetic heterogeneity or a new gene? - L. Lipton; H. J. W. Thomas; R. A. Eeles; R. S. Houlston; M. Longmuir; R. Davison; S. V. Hodgson; V. A. Murday; C. G. Norbury; C. Taylor; I. P. M. Tomlinson (Familial Cancer, 2001)

Instructions for authors (Familial Cancer, 2001)

Preventive measures in Peutz-Jeghers syndrome - Daniel R. McGrath; Allan D. Spigelman (Familial Cancer, 2001)

Familial adenomatous polyposis at the Tel Aviv Medical Center: demographic and clinical features - Paul Rozen; Ziona Samuel; Micha Rabau; Gideon Goldman; Ruth Shomrat; Cyril Legum; Avi Orr-Urtreger (Familial Cancer, 2001)

Café-au-lait spots and early onset colorectal neoplasia: a variant of HNPCC? - Jill D. Trimbath; Gloria M. Petersen; Steven H. Erdman; Merry Ferre; Michael C. Luce; Francis M. Giardiello (Familial Cancer, 2001)

Mutations of the 'minor' mismatch repair gene MSH6 in typical and atypical hereditary nonpolyposis colorectal cancer - Emanuela Lucci-Cordisco; Valentina Rovella; Stefania Carrara; Antonio Percesepe; Monica Pedroni; Alfonso Bellacosa; Oana Caluseriu; Mara Forasarig; Marcello Anti; Giovanni Neri; Maurizio Ponz de Leon; Alessandra Viel; et al. (Familial Cancer, 2001)

Familial breast cancer: an investigation into the outcome of treatment for early stage disease - Diana Eccles; Peter Simmonds; Jonathan Goddard; Marie Coultas; Shirley Hodgson; Fiona Lalloo; Gareth Evans; Neva Haites (Familial Cancer, 2001)

Chemotherapy resistant ovarian cancer in carriers of an hMSH2 mutation? - C. L. M. Marcelis; H. W. H. M. van der Putten; C. Tops; L. C. H. W. Lutgens; U. Moog (Familial Cancer, 2001)

FAP associated thyroid carcinoma in mother and her daughter - Kaori Kameyama; Hiroshi Takami (Familial Cancer, 2001)

Commentary on Eccles et al.: Familial breast cancer: an investigation into the outcome of treatment for early stage disease - Julia Wong; Judy Garber (Familial Cancer, 2001)

Desmoid tumour in familial adenomatous polyposis. A review of literature - Anne Lyster Knudsen; Steffen Bülow (Familial Cancer, 2001)

The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC) – Results of an international collaborative study - Wolfram Müller; Lawrence J. Burgart; Ruth Krause-Paulus; Stephen N. Thibodeau; M. Almeida; T. Brocker Edmonston; C. R. Boland; C. Sutter; J. R. Jass; A. Lindblom; J. Lubinski; K. MacDermot; et al. (Familial Cancer, 2001)

Editorial (Familial Cancer, 2001)

Instructions for authors (Familial Cancer, 2001)

Familial cancer database: a clinical aide-mémoire - Rolf H. Sijmons; Gerard T. N. Burger (Familial Cancer, 2001)

Cancer risk in mismatch repair gene mutation carriers - Patrice Watson; Henry T. Lynch (Familial Cancer, 2001)

Profuse familial adenomatous polyposis with an Adenomatous Polyposis Coli exon 3 mutation - Steven Nasioulas; Ian T. Jones; D. James B. St. John; Rodney J. Scott; Susan M. Forrest; R. J. McKinlay Gardner (Familial Cancer, 2001)

A paradox: urgent BRCA genetic testing - G. Mitchell; A. Ardern-Jones; M. Kissin Mchir; R. Taylor; R. A. Eeles (Familial Cancer, 2001)

Genotype and phenotype in hereditary nonpolyposis colon cancer: a study of families with different vs. shared predisposing mutations - Päivi Peltomäki; Xin Gao; Jukka-Pekka Mecklin (Familial Cancer, 2001)

Double primary cancers of the breast and thyroid in women: molecular analysis and genetic implications - Tuya Pal; Nancy Hamel; Danny Vesprini; Kevin Sanders; Margot Mitchell; Nada Quercia; Nathalie Ng Cheong; Angus Murray; William Foulkes; Steven A. Narod (Familial Cancer, 2001)

Women at risk of ovarian cancer: attitudes towards and expectations of the familial ovarian cancer clinic - Ruth Sheppard; Alison Fry; Robert Rush; C. Michael Steel; Ann Cull (Familial Cancer, 2001)

Population-based study of familial medullary thyroid cancer - Kari Hemminki; Chuanhui Dong (Familial Cancer, 2001)

Cytogenetic characteristics of oral squamous cell carcinomas in Fanconi anemia - Mario A. J. A. Hermsen; Yan Xie; Martin A. Rooimans; Gerrit A. Meijer; Jan P. A. Baak; John Th. M. Plukker; Fré Arwert; Hans Joenje (Familial Cancer, 2001)