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Despite their potential to inform sustainable regional harvest and climate‐resilient fisheries management, spatial stock assessment models remain underused for management advice. To identify barriers that inhibit broader use of these methods, we conducted a blinded international simulation experiment mimicking real‐world stock assessment development when confronting spatial complexity. Seven analyst teams built spatially aggre...
An endogenous human peptide derived from α1-antitrypsin as a novel pharmacological inhibitor of Bordetella pertussis toxinNARA Subscribed
Pertussis, also known as whooping cough, is a highly infectious respiratory disease caused by the bacterium Bordetella pertussis . The bacterial virulence factor, pertussis toxin (PT), is associated with the manifestation of the characteristic symptoms of pertussis and the severe form of this disease. Increasing case numbers and the lack of treatment options highlight the need to develop novel pharmacological strategies, e.g.,...
‘Drivin' with your eyes closed’: Results from an international, blinded simulation experiment to evaluate spatial stock assessmentsNARA Subscribed
Spatial models enable understanding potential redistribution of marine resources associated with ecosystem drivers and climate change. Stock assessment platforms can incorporate spatial processes, but have not been widely implemented or simulation tested. To address this research gap, an international simulation experiment was organized. The study design was blinded to replicate uncertainty similar to a real‐world stock assess...
Coupling pathway prediction and fluorescence spectroscopy to assess the impact of auxiliary substrates on micropollutant biodegradationNARA Subscribed
Some bacteria can degrade organic micropollutants (OMPs) as primary carbon sources. Due to typically low OMP concentrations, these bacteria may benefit from supplemental assimilation of natural substrates present in the pool of dissolved organic matter (DOM). The biodegradability of such auxiliary substrates and the impacts on OMP removal are tightly linked to biotransformation pathways. Here, we aimed to elucidate the biodegr...
Xylem formation patterns from Mediterranean to subalpine climate conditions reveal high growth plasticity of pine species on CorsicaNARA Subscribed
Key message Black pine and Maritime pine exhibit considerable differences in growth phenology across elevation belts with a 1-month delay for xylogenesis and increasing growth rates from low, mid to high elevations. Abstract Investigating seasonal wood formation is crucial to understand tree growth responses to climate impact. The present study quantifies the variability of xylogenesis along an elevation gradient on the Medite...