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High‐Throughput Sequencing in Aquaculture Disease Investigations: Challenges and Opportunities for ImplementationNARA Subscribed
The current generation of sequencing technologies can produce terabases of data with exceptional accuracy and speed, at a fraction of the cost of older methods. Despite this unprecedented power, adoption into aquaculture health management presents several challenges, including identifying where such capability may be optimally deployed. Here we synthesise discussions from a structured expert workshop held at the 2025 Aotearoa...
Lag in Effective Population Size Decline Amid Demographic Collapse: A Case Study of the Delta Smelt ( Hypomesus transpacificus )NARA Subscribed
Effective population size ( N e ), census size ( N c ) and their ratio ( N e / N c ) are widely used indicators in conservation genetics, yet long‐term empirical data tracking of all three metrics over long time scales in wild populations remains rare. Using monitoring data from 1995 to 2020, we examined temporal dynamics of N e , N c and their relationship during the demographic collapse of Delta Smelt ( Hypomesus transpacifi...
Ecology and Reproduction of Bunodeopsis in Tropical Northwestern Atlantic Seagrass EcosystemsNARA Subscribed
The seagrass ecosystems of the Tropical Northwestern Atlantic (TNA) host three described species of sea anemones in the genus Bunodeopsis Andres, 1881 (Enthemonae: Metridioidea: Acuticulata): B. antilliensis , B. globulifera , and B. pelagica . Due to their small size and nocturnal nature, many aspects of their basic biology and distribution remain unknown. To investigate their ecology and distribution, we surveyed five TNA ec...
Impacts of hybrid selection and nitrogen fertilization on root-derived carbon inputs in maizeNARA Subscribed
Background and Aims Root-derived carbon (C) inputs are increasingly recognized as important precursors to soil organic carbon (SOC). However, the extent to which these inputs can be influenced by nitrogen (N) fertilizer management and plant stature remains poorly understood. This study investigated how N fertilization rate and maize hybrid stature trade off between above- and belowground performance, including investment in ro...
Impact of sarcopenia and obesity on skeletal muscle size, gene expression, and mitochondrial functionNARA Subscribed
Skeletal muscle is a primary tissue of dysfunction during both aging and obesity. Recently, the coincidence of obesity and aging has gained attention due to the intersection of the obesity epidemic with an aging demographic. Both aging and obesity are associated with marked defects in skeletal muscle metabolic health. Despite these findings, we have a poor understanding of how obesity and aging may interact to impact skeletal...
Diet Driven Differences in Host Tolerance Are Linked to Shifts in Global Gene Expression in a Common Avian Host‐Pathogen SystemNARA Subscribed
Wildlife have become increasingly dependent on anthropogenic resources, altering interactions between individuals and subsequently disease transmission. Further, nutritional quantity and quality impact an individual's ability to mitigate damage caused by infectious disease. Thus, understanding how diet affects immune function is critical for predicting disease severity and transmission. Here, we use transcriptomics to explore...
Voxel-wise insights into early Alzheimer’s disease pathology progression: the association with APOE and memory declineNARA Subscribed
Longitudinal investigation of the Apolipoprotein E (APOE) genotype’s impact on Alzheimer’s disease (AD) biomarker progression, focusing on amyloid beta (Aβ) accumulation and gray matter (GM) atrophy, integrating cognitive decline and baseline levels. Longitudinal florbetapir-PET and T1-weighted MRI data from 100 cognitively normal (CN) and mild cognitive impaired (MCI) participants both with considerable global Aβ accumulation...
Optimising Outbreak Investigation, Surveillance and Discovery of Pathogens in Aquaculture Using Unbiased MetatranscriptomicsNARA Subscribed
Emerging infectious diseases are a major threat to global aquaculture production and are projected to increase in frequency due to anthropogenic stressors and climate change. Our ability to screen the global aquatic ‘infectome’ is dramatically improving through unbiased metatranscriptomic (i.e., total RNA) sequencing. Despite recent advances in molecular diagnostics and next‐generation sequencing, outbreak investigation in aqu...