Kelp forests are among the most extensive and productive coastal ecosystems, yet they remain underrepresented in global conservation policy despite widespread declines driven by interacting global- (i.e., ocean warming, marine heatwaves) to local-scale stressors. At the same time, kelp conservation and restoration efforts are expanding rapidly across regions, but measures of success and syntheses tend to primarily focus on eco...

The Golden Mahseer Tor putitora , is an endangered, migratory freshwater fish of ecological, commercial and cultural importance that inhabits foothill rivers in the Himalayas. This transboundary fish occurs across Bangladesh, Bhutan, India, Pakistan and Nepal, and is facing increasing pressures from multiple stressors including resource extraction and the rapid development of hydropower dams. The DRIFT ecosystem-based model wa...

The aim of this study is to investigate the association of neutrophil extracellular traps (NETs) markers with clinical and radiological outcomes in acute ischemic stroke (AIS) patients undergoing endovascular thrombectomy (EVT) and assess the effect of periprocedural heparin during EVT on NETs markers and their association with outcomes. From 198 AIS patients included in the MRCLEAN-MED trial, randomized to receive EVT with (...

The red wolf ( Canis rufus ) of the eastern US was driven to near‐extinction by colonial‐era persecution and habitat conversion, which facilitated coyote ( C . latrans ) range expansion and widespread hybridization with red wolves. The observation of some grey wolf ( C . lupus ) ancestry within red wolves sparked controversy over whether it was historically a subspecies of grey wolf with its predominant “coyote‐like” ancestry...

Rationale Schizophrenia is associated with impairments in cognitive functioning yet there are no approved drugs to treat these deficits. Objectives Based on animal models, we investigated the potential for roflumilast, a selective inhibitor of phosphodiesterase type 4 (PDE4), to improve cognition, which may act by increasing intracellular cyclic adenosine monophosphate in brain regions underlying cognitive deficits in schizoph...

Purpose Recombinant human erythropoietin (rHuEPO) is known to increase thrombotic risk in patients and might have similar effects in athletes abusing the drug. rHuEPO is prohibited by anti-doping legislation, but this risk has not been investigated thoroughly. This analysis was designed to evaluate whether rHuEPO impacts hemostatic profile and endothelial and platelet activation markers in trained subjects, and whether the com...

Summary The egg‐contaminating phenotype of Salmonella enterica serotype Enteritidis was linked to single‐nucleotide polymorphisms (SNPs) occurring in cyaA , which encodes adenylate cyclase that produces cAMP and pyrophosphate from ATP. Ribotyping indicated that SNPs in cyaA were linked to polymorphisms occurring in the rrlC and rrlA 23S ribosomal subunits. Phylogenetic analysis of cyaA discriminated between Salmonella enterica...

Although seldom studied, negatively buoyant river plumes may be common within large lakes, especially during spring when lake and river waters are near the temperature of maximum fresh water density (4°C) and relatively warm river discharge can be denser than the receiving lake water. Here we examine a negatively buoyant plume entering Lake Superior from the Ontonagon River during late March 2000. Because of small temperature...