Socio-environmental conflicts associated with large-scale economic projects in Indigenous territories are well documented, but conflicts in coastal areas remain largely unexplored, despite the crucial differences between inland and coastal ecosystems. While the empirical literature about socio-environmental conflicts in Indigenous territories in coastal areas is growing, the role of financial institutions and corporations in t...

Vascular endothelial cells in vivo are exquisitely regulated by their local environment, which is disrupted or absent when using methods such as FACS sorting of cells isolated from animals or in vitro cell culture. Here, we profile the gene expression patterns of undisturbed endothelial cells in living animals using a novel “AngioTag” zebrafish transgenic line that permits isolation of actively translating mRNAs from endotheli...

Purpose We assessed the effectiveness and safety of cefiderocol in patients with Gram-negative bacterial infections, excluding Acinetobacter spp., in the early access programme (EAP) in Spain. Methods The retrospective, multicentre PERSEUS study (2018–2022) enrolled hospitalised patients with serious Gram-negative infections, except Acinetobacter spp., who received first-time cefiderocol for ≥ 72 h following requests through t...

Purpose This subgroup analysis of the PERSEUS study aimed to describe the effectiveness of cefiderocol treatment in the early access programme in Spain in patients infected by Stenotrophomonas maltophilia , Burkholderia cepacia complex (Bcc) or Achromobacter species. Methods In the retrospective, observational, multicentre PERSEUS study in Spain, the effectiveness and safety of cefiderocol treatment administered for at least 7...

The blue economy approach to ocean governance promises environmentally sustainable, economically viable, and socially equitable ocean-based economic growth. However, the blue economy has been inconsistently defined, interpreted, and applied, often leading to incompatibilities between the blue economy approach and existing ocean policies. We explore the blue economy in the Republic of Panama, where recent government commitments...