A. Engel results 248
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Purpose Deepwater Horizon oil spill (DWHOS) responders potentially experienced multiple stressors. We examined associations between DWHOS deployment-related stressor patterns and neurological and endocrine/metabolic conditions among U.S. Coast Guard active duty responders who completed post-deployment surveys (n = 3102). Methods Deployment-related stressor patterns were identified using principal component analysis of self-rep...
Cancer Risk and Mortality Following Kaposi Sarcoma Among People with HIV in the United States, 2000 to 2019NARA Subscribed
People with HIV (PWH) have increased Kaposi sarcoma (KS) risk. Among 2,645 PWH with KS in the United States HIV/AIDS Cancer Match Study, subsequent cancer risk was elevated 2.8-fold (95% confidence interval [CI]: 2.4–3.3) compared to PWH without KS. Mortality after KS declined 2000–2002 and 2012–2015 (hazard ratio = 0.64; 95%CI: 0.55–0.74).
Validity of V̇O2max estimates from the forerunner 245 smartwatch in highly vs. moderately trained endurance athletesNARA Subscribed
Purpose Assessing the validity of maximum oxygen uptake (V̇O₂ max ) estimates provided by a commercially available smartwatch (Garmin Forerunner 245, Garmin Ltd., Olathe, USA) compared to laboratory-based respiratory gas analysis in moderately-to-highly trained athletes. Methods Thirty-five endurance athletes (Tier 2–3 athletes, 24 males, 11 females; age: 25.1 ± 3.5 years; V̇O₂ max : 60.1 ± 8.2 ml·min⁻ 1 ·kg⁻ 1 ) completed a t...
The CALHM1 blocker CGP37157 increases seizure severity during status epilepticus in adult miceNARA Subscribed
Epilepsy is one of the most common chronic brain diseases affecting up to 70 million people worldwide. Major challenges of epilepsy treatment include the high pharmacoresistance in patients and the lack of disease-modification. Extracellular adenosine 3’triphosphate (ATP), a key neurotransmitter in the activation of the purinergic signalling system, is increasingly recognized to contribute to pathological brain hyperexcitabili...
Purpose Worksite health promotion programs (WHPPs) are able to promote a healthier lifestyle for blue-collar workers in freight transport, yet their participation is generally low. This study aims to identify different health lifestyle classes among blue-collar workers in freight transport and investigate the relationship between class membership and WHPP participation. Methods Data from 16,897 employees were obtained from an...