A. Freeman results 221
· Newest (Page 1/9, per page 25)
Author: A. Freeman ×Clear All Filters
Search Results
The storage potential for gas in geologic settings, such as depleted hydrocarbon reservoirs and solution-mined salt caverns, is becoming salient to future energy infrastructure planning. Technologies such as carbon capture, utilization, and storage, carbon dioxide-enhanced oil recovery, and natural gas and hydrogen storage help meet growing energy demands, reduce carbon emissions to meet climate goals, and provide energy secur...
The decline in estrogen following menopause is a major driver of metabolic and immune dysfunction in aging females. While hormone replacement therapy improves many of these outcomes, its clinical use remains limited due to concerns regarding estrogen-sensitive malignancies. Tissue-selective estrogen complexes (TSECs), which combine estrogens with selective estrogen receptor modulators (SERMs) such as tamoxifen (TAM), represent...
Pacific Northwest birds have shifted their abundances upslope in response to 30 years of warming temperaturesNARA Subscribed
Mountain species are predicted to respond to warming temperatures by moving to higher elevations that remain relatively cool. Species can track warming by shifting their entire distributions upwards (the “escalator to extinction” hypothesis) or by increasing in abundance in the upper portion of their elevational range while maintaining stable elevational limits (the “upslope lean” hypothesis). Alternatively, mountain species m...
Methylation array signals are predictive of chronological age without bisulfite conversionNARA Subscribed
DNA methylation data has been used to make “epigenetic clocks” which attempt to measure chronological and biological aging. These models rely on data derived from bisulfite-based measurements, which exploit a semi-selective deamination and a genomic reference to determine methylation states. We found that non-methylation factors lead to “pseudomethylation” signals that are both confounding of epigenetic clocks and uniquely age...
Challenges and opportunities for integrating social science in a conservation nongovernmental organizationNARA Subscribed
Although the importance of social science to conservation practice and policy is well accepted, social scientists remain in the minority in conservation nongovernmental organizations (NGOs). We explored how social science has started to inform the work of WWT, an NGO dedicated to the restoration of wetlands for people and nature. Through reflections on our experiences working in WWT's social dimensions unit and interviews with...