Sporothrix brasiliensis biofilms represent a challenge in the treatment of sporotrichosis due to their structural complexity and antifungal resistance. This study evaluated the efficacy of terbinafine (TERB) and itraconazole (ITZ), and their synergism against biofilms of yeast-like forms of S. brasiliensis . Seven clinical strains were analyzed for biofilm formation and structural alterations using spectrophotometry, confocal...