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Purpose To explore how hospital interns and residents specialising in family medicine act on drug interaction alerts in a specific patient case, and on interaction alerts in general. Methods A 4-page questionnaire, including a fictional patient case (73-year-old woman; 10 drugs in the medication list triggering 11 drug interaction alerts) and questions regarding the use of interaction alerts in general, was distributed to inte...
Purpose To analyse the reliability and validity of the Swedish indicator ‘Drugs that should be avoided in older people’. Methods From a previous study that included consecutive primary care patients ≥ 65 years of age, all patients ≥ 75 years of age were analysed. Two physicians independently screened their medication lists and medical records, applying the Swedish indicator which includes potentially inappropriate medications...
Numerous marine invertebrates form symbiotic relationships with single-celled algae, termed “photosymbioses”, and the diversity of these interactions is likely underestimated. We examined Phidiana lynceus , a cladobranch sea slug that feeds on photosymbiotic hydrozoans. We assessed its ability to acquire/retain algal symbionts by examining specimens in starvation, finding that P. lynceus is able to incorporate and retain symbi...
Purpose To investigate the clinical relevance of potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs), and to evaluate the association between PIMs/PPOs and inadequate drug treatment. Methods PIMs/PPOs, concordantly identified by two physicians applying the STOPP/START criteria, the EU(7)-PIM list, and a Swedish set in 302 consecutive older primary care patients, were assessed regarding clini...
Drug interaction alerts in older primary care patients, and related medically justified actionsNARA Subscribed
Purpose To describe presented interaction alerts in older patients, and the extent to which these require further medical action for the specific patient or are already being addressed. Methods Interaction alerts presented at a physician consultation, for 274 consecutive primary care patients treated with two or more drugs (median age: 75 years; 59% female), were extracted. These alerts are based on J anusmed, a decision suppo...
The predictive capacity of the high resolution weather research and forecasting model: a year-long verification over ItalyNARA Subscribed
Numerical models are operationally used for weather forecasting activities to reduce the risks of several hydro-meteorological disasters. The overarching goal of this work is to evaluate the Weather Research and Forecasting (WRF) model predictive capabilities over the Italian national territory in the year 2018, in two specific cloud resolving configurations. The validation is carried out with a fuzzy logic approach, by compar...
The region near the Ligurian Sea in northwestern Italy occasionally experiences extreme rainfall events that can lead to catastrophic flooding. These events are often caused by back‐building mesoscale convective systems whose occurrence peaks during the autumn. Rapid warming of the Mediterranean Sea in recent decades has raised concerns that the warmer water may change the frequency or intensity of these rainfall events. To ga...
Effects of storage time on the motility, mortality and calcium levels of Atlantic salmon Salmo salar spermatozoaNARA Subscribed
This study estimates spermatozoa mortality, morphology, motility and intracellular calcium levels in Atlantic salmon Salmo salar milt after prolonged storage. Milt samples were preserved at 4° C for 25 days and then evaluated for mortality. Motility remained high for the first 3 days and the mortality was low during the first 5 days of storage. A decrease of >50% in calcium content was observed after 5 days of storage. When sp...
Immersion anaesthesia with tricaine methanesulphonate or propofol on different sizes and strains of silver catfish Rhamdia quelenNARA Subscribed
The efficacy of immersion anaesthesia with tricaine methanesulphonate (MS222) or propofol on albino and grey silver catfish Rhamdia quelen was assessed through induction and recovery times and observation of mortality. Besides reporting a novel, efficient and practical use of propofol as an immersion anaesthetic, the study shows that it is essential to consider size and strain when anaesthetizing R. quelen with MS222 or propof...