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Standardized microhaplotype databases and frameworks for assessing and mining crop genetic diversityNARA Subscribed
Keymessage Standardized microhaplotype databases for eight diverse crops enable multiallelic analyses, comparative genetics, and breeding decisions. Abstract Microhaplotypes are short genomic segments that contain multiple tightly linked variants, providing multi-allelic data that can enhance genetic resolution compared to traditional biallelic single nucleotide polymorphism (SNP) markers. Here, we present the creation and uti...
Gulf sturgeon are federally listed as “threatened” and are native to seven rivers along the northern Gulf of Mexico. Populations natal to the Pascagoula River have one verified spawning reach in the lower Bouie River, near Hattiesburg, MS. This reach is modified by four aggregate mining areas, referred to as pits. Researchers observed post-spawn Gulf sturgeon over-summering in pits rather than migrating to downstream holding a...
Mechanisms of breast cancer dormancy in bone metastasisNARA Subscribed
Bone metastasis remains a serious threat to breast cancer patients. This condition arises from the outgrowth of previously dormant tumour cells in this site. Dormant tumour cells are almost impossible to detect in human patents, and these cells acquire “stem like” characteristics rendering them resistant to current cancer therapies. Furthermore, the development of therapies to target this population has proved challenging. The...
Behavioral variation across multiple phases of intravenous cocaine self-administration among genetically diverse mouse populationsNARA Subscribed
Genetic and other predisposing factors can influence the progression from initiation of drug intake to compulsive substance use through distinct biobehavioral processes. Operant cocaine self-administration studies in laboratory mice offer a powerful method to dissect the biology of this progression from initiation, dose-response, extinction, and cued reinstatement in a controlled, tractable system. However, many such studies e...
SNAPSHOT USA 2024: Year 6 of the Coordinated National Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multi‐contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of speci...
Entanglement is one of the primary anthropogenic threats to the North Atlantic right whale ( Eubalaena glacialis ; right whale) whose habitat overlaps fixed-gear fishing grounds in the Northwest Atlantic with entanglements representing around half of the mortality and serious injury incidents. Right whale mortality has reached levels that require intervention under the Marine Mammal Protection Act, creating the need for a tool...
Steady-state P800 oxidation kinetics indicate that heliobacterial phototrophy is light-limitedNARA Subscribed
The heliobacteria are a family of phototrophic bacteria known for their unique production of bacteriochlorophyll g and for their use of the simplest known Type I reaction center. In this work, we characterize P800 oxidation kinetics in whole cells of Heliomicrobium modesticaldum under the continuous illumination that is more consistent with in vivo conditions, an area of research that remains largely unexplored. When assayed a...