Inborn errors of immunity (IEI) are rare heritable disorders of the immune system predisposing to atypical infections, autoimmunity, inflammation, and risk of malignancy. Adaptation is the process of incorporating stressful experiences into one’s life; these experiences may include onset of illness, receiving a diagnosis, or suffering without a diagnosis. Poor adaptation is linked to adverse outcomes including psychiatric como...

Single‐celled microbial eukaryotes inhabit deep‐sea hydrothermal vent environments and play critical ecological roles in the vent‐associated microbial food web. 18S rRNA amplicon sequencing of diffuse venting fluids from four geographically‐ and geochemically‐distinct hydrothermal vent fields was applied to investigate community diversity patterns among protistan assemblages. The four vent fields include Axial Seamount at the...

On the basis of ERA40 and NCEP/NCAR Reanalysis (NNR) and simulations from CCCma, CCSM, CSIRO, HadCM3, MIROC‐MEDRES and GFDL, which support the Intergovernmental Panel on Climate Change (IPCC) 4th Assessment Report (AR4), we demonstrated that the amplitude of the annual and the semi‐annual harmonics delivered by the ERA40 and NNR is dominated by distinct seasonal variability. The maximum first harmonic amplitude of near surface...