Lornoxicam-loaded chitosan-coated Litsea lipid nanocarriers (LRX-CS-LLCs) were developed as an innovative oral delivery system, combining the synergistic anti-inflammatory effects of Litsea cubeba oil with the mucoadhesive properties of chitosan. The GC/MS analysis of Litsea cubeba oil identified α -citral (47.56%), β -citral (26.86%), and D -limonene (14.00%). Various LRX-loaded LLCs were prepared and optimized. Fourier trans...

The type II collagen-induced arthritis (CIA) model and human rheumatoid arthritis exhibit similar characteristics. Both diseases involve the production of inflammatory cytokines and other mediators, triggering an inflammatory cascade linked to bone and cartilage damage. Recently, new pyrazole compounds with various pharmacological activities, including antimicrobial, anticancer, anti-inflammatory, and analgesic agents, have be...

The use of phytobiotic as functional feed additives is a promising inducer for growth performance and immune response in the Pacific whiteleg shrimp ( Litopenaeus vannamei ). It can be also commercially applied in combination with chemotherapeutic agents and vaccines. This study was carried out to evaluate the use of a commercial phytobiotic feed additive, Sanacore® GM, containing vegetable fatty acids and inactivated Saccharo...

The use of phytotherapy in aquaculture is rapidly increasing for more environmentally sustainable measures. The present work aimed to investigate the effects of different dietary levels of sweet basil, Ocimum basilicum , leaves ethanol (BEE) or aqueous (BAE) extracts (0, 200, 300, and 500 mg/kg) on Oreochromis niloticus growth, digestive enzyme activities, hemato-biochemical profile, antioxidant status, immune responses, and r...