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White Spot Syndrome Virus (WSSV) is known to cause significant mortality in farmed shrimp, including black tiger shrimp ( Penaeus monodon ) and white leg shrimp ( Litopenaeus vannamei ) across several countries. Prolonged infections with WSSV are difficult to eliminate with traditional methods like vaccinations, probiotics, and immunostimulants. Herein, we assessed the antiviral effectiveness of two medicinal plants, Cydonia o...
Development of Novel Egg Yolk Antibody ( IgY )–Based Immunological Tools for the Early Detection of White Spot Syndrome Virus in ShrimpNARA Subscribed
The white spot syndrome virus (WSSV) is a major threat to shrimp farming and causes substantial economic losses in aquaculture. The VP28 envelope protein of WSSV facilitates initial systemic infection in shrimp. Although mammalian‐derived antibodies are used for diagnostic tests, high costs and animal welfare concerns necessitate alternative strategies. This study produced specific yolk immunoglobulin (IgY) by immunising layin...
Introduction The Arabian Gulf (Gulf) is a dynamic marine ecosystem in which phytoplankton productivity, indicated by Chlorophyll- a (Chl- a ), is strongly affected by environmental and climatic variables. Understanding the spatiotemporal variability of Chl- a and its driving environmental factors is critical for assessing primary productivity and ecosystem dynamics of the Gulf. Methods This study investigated the long-term Chl...
Immune Response and Protective Efficacy of Quercetin in Tilapia, Oreochromis niloticus Against Tilapia ParvovirusNARA Subscribed
The global tilapia farming industry is facing challenges due to tilapia parvovirus (TiPV), an emerging viral pathogen affecting cultured tilapia populations worldwide. It causes mass mortality in tilapia and high economic loss. Hence, an effective treatment is needed to control TiPV infection. Quercetin is one of the polyphenolic flavonoid compounds found in many natural products and could effectively inhibit various aquatic v...
Recent Advances in Bioanalytical Methods for Quantification and Pharmacokinetic Analyses of Antibody–Drug ConjugatesNARA Subscribed
Antibody–drug conjugates (ADCs) represent a rapidly expanding class of therapeutics, uniquely combining the specificity of monoclonal antibodies with the potency of cytotoxic small-molecule payloads. Due to their inherent structural complexity and heterogeneous composition, accurate characterization and quantification of ADCs pose significant bioanalytical challenges. This review discusses recent advancements in bioanalytical...