Melatonin is a powerful endogenous antioxidant hormone. Its healing effects on energy balance and neuronal damage associated with oxidative metabolism disorders have been reported in pathologic conditions. We aimed to determinate the utility of melatonin on neuronal damage, synaptic transmission, and energy balance in the brain tissue of rats with sepsis induced with LPS. Rats was divided into four groups such as control, LPS...

Water loss management (WLM) in water distribution systems (WDSs) is generally time consuming, costly and difficult. Therefore, the most appropriate methodology should be defined based on the current status, requirements and technical capacity of the utilities. In this study, a novel WLM model was developed to improve the WLM practices, to define the most appropriate and applicable targets and to determine the components that n...