Neoadjuvant chemotherapy is the foundation treatment for triple-negative breast cancer (TNBC) and frequently results in pathological complete response (pCR). However, there are large differences in clinical response and survival after neoadjuvant chemotherapy of TNBC patients. The aim was to identify genes whose expression significantly associates with the efficacy of neoadjuvant chemotherapy in patients with TNBC. Transcripto...

Agastache rugosa (Fisch. & C. A. Mey.) Kuntze known as Korean Mint is a medicinal and aromatic plant containing rosmarinic acid as a major bioactive polyphenol but its content in this herbal drug is variable. Plant in vitro culture is one of the approaches used to overcome the complexity of environmental factors influencing phytochemical profiles in medicinal plants. In this study, hairy root cultures of A. rugosa were establi...

Cancer is the second most common cause of death in Poland and the number of new cases is expected to increase by 28% over the next 10 years. Despite modifications and expenditure growth in the Polish health care system, oncological treatment outcomes are lower comparing to the other European Union countries. Early preventative interventions are effective in reducing the total number of cancers and improving early detection. On...

Moluccella laevis L. ( Lamiaceae ) is an annual ornamental plant, naturally occurring in the areas of Western and Central Asia (Irano-Turanian area). It is a popular ornamental species, but its phytochemical profile remains poorly studied. This study presents the first report on in vitro cultures of M. laevis . The influence of two types of illumination and plant growth regulators (PGRs) supplementation on the morphogenetic re...