Neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), can be clinically heterogeneous which may be explained by the co-inheritance of multiple genetic variants that modify the clinical course. In this study we examine variants in three genes in a family with one individual presenting with ALS and lipodystrophy. Sequencing revealed a p.Gly602Ser variant in LMNA , and two additional variants, one each in SET...

Human impacts on aquatic biodiversity are often measured at the assemblage or community level, although it has been suggested that individual‐level measures are more sensitive. We evaluated the effects of anthropogenic sedimentation on endemic snails in Lake Tanganyika, East Africa, by comparing assemblage‐level (i.e., species richness, evenness, and abundance) and individual‐level (i.e., frequencies of predation and parasitis...