Aim We aim to investigate the environmental drivers shaping macroecological patterns of phylogenetic structure in plants, using the cactus family (Cactaceae) as a model group. Major Taxa and Location Cactus family (Cactaceae), comprising 1892 species, distributed across the American continent (approximately 42 million km 2 ). Methods We compiled a robust dataset of 435,694 occurrence records and estimated two complementary met...