Background Hemodynamic instability during colonoscopy sedation remains a significant clinical concern. Esketamine’s sympathomimetic properties may protect against these risks while reducing sedative requirements. Hence, we aim to evaluate the efficacy and safety of esketamine in improving intraprocedural sedation during colonoscopy. Methods We systematically searched PubMed, Scopus, CENTRAL, and Web of Science until June 2025...

Given the recurrent waves of COVID-19 and the emergence of new viral infections, optimizing the potential of remdesivir as an antiviral agent is critical. While several reviews have explored the efficacy of remdesivir, few have comprehensively addressed its challenges, such as the necessity for intravenous infusion, suboptimal lung accumulation, and safety concerns related to its formulation. This review critically examines th...

This paper reports on the results of an experimental study on the flexural performance of recycled-aggregate concrete beams reinforced with basalt fiber-reinforced polymer (BFRP) bars. A total of eight reinforced concrete (RC) beams were prepared and tested under four-point loading. The parameters investigated included: (1) concrete mixture (0, 25, 50, and 100% use of recycled concrete aggregates (RCA)) and (2) reinforcement m...

The present study recorded for the first time, an occurrence of Oligocene basaltic plugs in Beni-Suef Governorate, Egypt. In addition, Egyptian alabaster was discovered in the study area, further the well-known ancient area around the Cavern of Wadi Sannur. In this work, the lithostratigraphy, structure, petrography, and geochemistry including TGA and DSC were studied. In addition, the thermal effect of the basaltic magma on t...

Bee pollen is a healthy product with a good nutritional profile and therapeutic properties. Its high moisture content, however, promotes the growth of bacteria, molds, and yeast during storage commonly result in product degradation. Therefore, the aim of this study is to assess the effectiveness of gamma irradiation (GI) and ozone (OZ) as bee pollen preservation methods for longer storage time, as well as whether they are infl...

Schistosoma mansoni is the main factor of human schistosomiasis which is responsible for high rates of mortality. Recently, the use of alternative biological control agents has gained importance in disease control because the intensive use of molluscicides is very harmful to human health and poses risks to the environment. In the present work, the potential effect of two freshwater algae, Amphora coffeaeformis and Scenedesmus...

Wadi Mawathil area is characterized by the existence of carbonates, represented by “Egyptian Alabaster” (calcite alabaster) and “Bucchino” (recrystallized limestone). One of the most important geological heritage in Egypt is the Egyptian Alabaster quarries. The “Egyptian Alabaster” is considered the main economic resource in the study area and the recrystallized limestone occasionally can be quarried. Field study revealed that...

Establishing spatial correspondence between subject and template images is necessary in neuroimaging research and clinical applications such as brain mapping and stereotactic neurosurgery. Our anatomical fiducial (AFID) framework has recently been validated to serve as a quantitative measure of image registration based on salient anatomical features. In this study, we sought to apply the AFIDs protocol to the clinic, focusing...