Alessandro Monaco results 8
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Selective Reduction of Ca2+ Entry Through the Human NMDA Receptor: a Quantitative Study by Simultaneous Ca2+ and Na+ ImagingNARA Subscribed
Excessive Ca 2+ influx through N-methyl-D-aspartate type glutamate receptors (NMDAR) is associated with excitotoxicity and neuronal death, but the inhibition of this receptor-channel causes severe adverse effects. Thus, a selective reduction of NMDA-mediated Ca 2+ entry, leaving unaltered the Na + current, could represent a valid neuroprotective strategy. We developed a new two-fluorophore approach to efficiently assess the Ca...
SARS-CoV-2 antibodies in inflammatory neurological conditions: a multicentre retrospective comparative studyNARA Subscribed
It is well established that neurological and non-neurological autoimmune disorders can be triggered by viral infections. It remains unclear whether SARS-CoV-2 infection induces similar conditions and whether they show a distinctive phenotype. We retrospectively identified patients with acute inflammatory CNS conditions referred to our laboratory for antibody testing during the pandemic (March 1 to August 31, 2020). We screened...
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