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Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
The routine generation of species distribution data at scale remains a challenge. We used aquatic environmental DNA metabarcoding to sample vertebrate species across the 30,000 km 2 Gaoligongshan region along the China–Myanmar border. In just 56 calendar days (33 researcher‐field‐days + 69 researcher‐lab‐days), we detected 389 vertebrate species, of which 35 are Red‐Listed. We introduce the ‘eDNA‐aware’ OccPlus occupancy model...
Trends in the incidence of cancers of the male genital system and urinary bladder in Harare, Zimbabwe, 1990–2019NARA Subscribed
Purpose The cancer registry of Harare, Zimbabwe, founded in 1986 allows the study of the evolution of the cancer epidemic in a Black (African) population over a 30-year period, and is used to investigate trends in the incidence of cancers of the male genital system and urinary tract. Methods Age standardised incidence rates (ASRs) in the black (African) population of Harare are calculated for four cancers: prostate, testis and...
Aim Plant functional traits can influence interaction outcomes between nurse and target plants through a “functional trait match”, which occurs when the traits of nurse plants ameliorate their environment, and target plants possess traits that allow them to benefit from this ameliorated environment. We investigated how the traits of putative nurse species affect interaction outcomes across global drylands and determined the fu...