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Developing Self Care Digital Trainings for Cancer Patients: An Implementation Research Project with Broad Stakeholder EngagementNARA Subscribed
Cancer-related fatigue and sleep problems are common and burdensome symptoms affecting many cancer patients. Mind Body Medicine techniques, such as acupressure and mindfulness-based techniques, have been shown to be effective in alleviating these symptoms. However, opportunities for patients to learn and apply these self care techniques are limited. This study aimed to develop two digital training programs to enable cancer pat...
An endogenous human peptide derived from α1-antitrypsin as a novel pharmacological inhibitor of Bordetella pertussis toxinNARA Subscribed
Pertussis, also known as whooping cough, is a highly infectious respiratory disease caused by the bacterium Bordetella pertussis . The bacterial virulence factor, pertussis toxin (PT), is associated with the manifestation of the characteristic symptoms of pertussis and the severe form of this disease. Increasing case numbers and the lack of treatment options highlight the need to develop novel pharmacological strategies, e.g.,...
Amplified warming and marine heatwaves in the North Sea under a warming climate and their impactsOA Marine
The northeast Atlantic and adjacent regions, such as the North Sea, are among the fastest-warming areas in the world. However, the role of climate change and internal variability in marine heatwaves (MHWs) in this region remains poorly understood. This study aims to quantify the relevant changes in sea surface temperature (SST) and MHWs in the North Sea, as well as to identify the leading patterns of interannual MHW variabilit...
In our study we investigated the hydrodynamic circulation of the Gulfs of Patras and Corinth through modelling. To this end, ROMS was used to numerically calculate the parameters of the waters for these peculiar semi-enclosed basins. Several oceanographic forcings were used with an emphasis on the tides and the winds. With several simulations, each focusing on a specific element, we were able to describe more accurately the dy...
In this work we present a super-resolution approach for deriving high-spatial-resolution and high-temporal-resolution ocean colour satellite datasets. The technique is based on DINEOF (data-interpolating empirical orthogonal functions), a data-driven method that uses the spatio-temporal coherence of analysed datasets to infer missing information. DINEOF is used here to effectively increase the spatial resolution of satellite d...
Satellite observations provide a global or near-global coverage of the World Ocean. They are however affected by clouds (among others), which severely reduce their spatial coverage. Different methods have been proposed in the literature to reconstruct missing data in satellite observations. For many applications of satellite observations, it has been increasingly important to accurately reflect the underlying uncertainty of th...
In this study, we examined the long-term spatiotemporal trend of marine heatwaves (MHW) and marine cold spells (MCS) characteristics in the southern North Sea over the last four decades (1982-2021). We then estimated the difference between their annual mean values and the possible relationship with the large-scale climate modes of natural sea surface temperature (SST) and atmospheric variability using satellite SST data. The S...
In the past several years, the capabilities of optical tools and in situ imaging devices have greatly expanded and are now revolutionizing the field of plankton research. These tools have facilitated the discovery of new plankton and enhanced the understanding of populations of fragile and gelatinous zooplankton. Imaging devices are becoming more accessible and regularly deployed on oceanographic studies and monitoring efforts...
Marine heatwaves (MHWs) are discrete warm-water anomalies events occurring in both open ocean and coastal areas. These phenomena have drawn researchers’ attention since the beginning of the 2010s, as their frequency and intensity are severely increasing due to global warming. Their impacts on the oceans are wide, affecting the ecosystems thus having repercussions on the economy by decreasing fisheries and aquaculture productio...
In this paper, we outline the need for a coordinated international effort toward the building of an open-access Global Ocean Oxygen Database and ATlas (GO 2 DAT) complying with the FAIR principles (Findable, Accessible, Interoperable, and Reusable). GO 2 DAT will combine data from the coastal and open ocean, as measured by the chemical Winkler titration method or by sensors (e.g., optodes, electrodes) from Eulerian and Lagrang...
Satellite-derived estimates of ocean color variables are available for several decades now and allow performing studies of the long-term changes occurred in an ecosystem. A daily, gap-free analysis of chlorophyll (CHL) and suspended particulate matter (SPM, indicative of light availability in the subsurface) at 1 km resolution over the Greater North Sea during the period 1998–2020 is presented. Interannual changes are describe...
DIVAnd (Data-Interpolating Variational Analysis, in n -dimensions) is a tool to interpolate observations on a regular grid using the variational inverse method. We have extended DIVAnd to include additional dynamic constraints relevant to surface currents, including imposing a zero normal velocity at the coastline, imposing a low horizontal divergence of the surface currents, temporal coherence and simplified dynamics based on...
The OceanGliders program started in 2016 to support active coordination and enhancement of global glider activity. OceanGliders contributes to the international efforts of the Global Ocean Observation System (GOOS) for Climate, Ocean Health, and Operational Services. It brings together marine scientists and engineers operating gliders around the world: (1) to observe the long-term physical, biogeochemical, and biological ocean...
Traditionally, in order for lower-resolution, global- or basin-scale (regional) models to benefit from some of the improvements available in higher-resolution subregional or coastal models, two-way nesting has to be used. This implies that the parent and child models have to be run together and there is an online exchange of information between both models. This approach is often impossible in operational systems where differe...