Ali M. Sayed results 138
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Effect of milling on natural radioactivity of Egyptian zircon sand: an assessment of alpha and beta radiation emissionsNARA Subscribed
This study aims to investigate the effect of milling on the natural radioactivity of Egyptian zircon sand, focusing on the gross alpha (α) and goss beta (β) activity concentrations, with additional evaluation of calcination and sulfuric acid leaching. Zircon samples were milled for different durations, and their gross α and gross β activity concentrations were measured using an ATOMTEX AT1329 sample counter. The measurements s...
Antioxidant and anti-apoptotic effects of curcumin-loaded nanoliposomes against di-n-butyl phthalate-induced hepatorenal damage in ratsNARA Subscribed
Di-n-butyl phthalate (DBP) is a conventional plasticizer known to induce hepatotoxicity and nephrotoxicity through oxidative stress and apoptosis. In contrast, curcumin, a polyphenolic compound from Curcuma longa , has significant antioxidant and anti-apoptotic activity; however, its therapeutic efficiency is limited due to poor absorption and low bioavailability. Nanoliposomes can significantly enhance the stability and absor...
The intensive mariculture of S. aurata can promote aquaculture development, although it can also pose challenges because of predatory behavior and environmental stressors caused by intensification. The objective of this study is to alleviate stress and prevent cannibalism, thereby improving the fish’s performance and welfare. A 90-day growth experiment investigated the dietary inclusion of melatonin (ML) on Sparus aurata perfo...
Nano-curcumin mitigates aluminum oxide nanoparticle toxicity in Nile tilapia through antioxidant and immune modulationNARA Subscribed
Our study investigated the toxicological effects of aluminum oxide nanoparticles (Al 2 O 3 -NPs) and the potential protective role of dietary nano-curcumin (N-CUR) in juvenile Oreochromis niloticus (30.39 ± 0.05 g) under controlled experimental conditions. It was hypothesized that N-CUR could mitigate the adverse impacts of Al 2 O 3 -NPs on growth, biochemical, oxidative, and histopathological parameters. A total of 180 O. nil...
Neuroprotection by canagliflozin in a Huntington’s disease model: role of HIF-1α and PI3K/AKT signalingNARA Subscribed
Huntington’s disease (HD) is a progressive neurodegenerative disorder characterized by motor, cognitive, and metabolic dysfunction, largely driven by mitochondrial impairment and defective energy metabolism. Altered signaling through hypoxia-inducible factor-1α (HIF-1α) and PI3K/AKT cascades contributes to neuronal vulnerability. Canagliflozin (Cana), a sodium–glucose cotransporter-2 inhibitor, has shown cognitive benefits in...