Alice Marie results 76
· Newest (Page 1/4, per page 25)
Author: Alice Marie ×Clear All Filters
Search Results
Cities at Sea: Coastal Urbanization Generates Local Biodiversity Hotspots but Homogenizes Marine Fish Communities RegionallyNARA Subscribed
Urbanization is rapidly expanding along the world's coasts, transforming natural ecosystems into increasingly uniform artificial environments. Yet, the patterns and processes shaping marine biodiversity under urban pressure remain poorly understood. We investigated whether coastal urbanization drives marine communities toward greater similarity, a process well documented in terrestrial and freshwater systems as urban biotic ho...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
Technical Considerations of Pharmacokinetic Assays for LNP-mRNA Drug Products by RT-qPCRNARA Subscribed
Lipid nanoparticle-messenger RNA (LNP-mRNA) drug products are a growing class of drug modalities. The unique composition of these drug products requires multiple measurements to account for the different components of these drug modalities. Pharmacokinetic (PK) measurements include measurement of the encapsulated mRNA and components of the LNP in circulation to understand the effectiveness of the therapeutic mRNA. The PK measu...
Voxel-wise insights into early Alzheimer’s disease pathology progression: the association with APOE and memory declineNARA Subscribed
Longitudinal investigation of the Apolipoprotein E (APOE) genotype’s impact on Alzheimer’s disease (AD) biomarker progression, focusing on amyloid beta (Aβ) accumulation and gray matter (GM) atrophy, integrating cognitive decline and baseline levels. Longitudinal florbetapir-PET and T1-weighted MRI data from 100 cognitively normal (CN) and mild cognitive impaired (MCI) participants both with considerable global Aβ accumulation...
Toward independence: maternal social status and experience shape mother–infant relationships in mandrillsNARA Subscribed
Mammalian species with slow life histories invest heavily in offspring care to meet offspring nutritional and developmental requirements, typically at significant costs to mothers. While maternal care has been extensively studied, understanding the mechanisms driving variation in mother‒offspring relationships during key offspring developmental periods require more comparative data from natural populations. Using eight years o...
The Surface Water and Ocean Topography (SWOT) mission delivers unprecedented swath-altimetry products. Despite SWOT's 2D coverage and precision, its Level-2 ocean products suffer from the same limitations as their counterparts from nadir altimetry missions. To achieve the mission's primary science objectives, the space agencies generate Level-2 ocean products with SWOT alone. In contrast, some research domains and applications...
Real-time observation of ocean surface topography is essential for various oceanographic applications. Historically, these observations have mainly relied on satellite nadir altimetry data, which were limited to observation scales greater than approximately 60 km. However, the recent launch of the wide-swath Surface Water Ocean Topography (SWOT) mission in December 2022 marks a significant advancement, enabling the two-dimensi...