Alison Graham results 41
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The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
Carbon footprints of greenhouse gas mitigation measures for a grass-based beef cattle finishing system in the UKNARA Subscribed
Purpose Agri-food systems across the globe are faced with the challenge of reducing their supply-chain emissions of greenhouse gases (GHGs) such as nitrous oxide (N 2 O), carbon dioxide (CO 2 ), and methane (CH 4 ). For instance, 10% of the UK’s GHG emissions are generated by agriculture, and ~ 56% of these are generated by livestock production. Numerous mitigation measures are being proposed to reduce GHG emissions from rumin...
Germline copy number variants and endometrial cancer riskNARA Subscribed
Known risk loci for endometrial cancer explain approximately one third of familial endometrial cancer. However, the association of germline copy number variants (CNVs) with endometrial cancer risk remains relatively unknown. We conducted a genome-wide analysis of rare CNVs overlapping gene regions in 4115 endometrial cancer cases and 17,818 controls to identify functionally relevant variants associated with disease. We identif...
Identification of genetic loci in lettuce mediating quantitative resistance to fungal pathogensNARA Subscribed
Key message We demonstrate genetic variation for quantitative resistance against important fungal pathogens in lettuce and its wild relatives, map loci conferring resistance and predict key molecular mechanisms using transcriptome profiling. Abstract Lactuca sativa L. (lettuce) is an important leafy vegetable crop grown and consumed globally. Chemicals are routinely used to control major pathogens, including the causal agents...
Sharing and reporting benefits from biodiversity researchNARA Subscribed
Assembly and characterisation of a unique onion diversity set identifies resistance to Fusarium basal rot and improved seedling vigourNARA Subscribed
Key message A unique, global onion diversity set was assembled, genotyped and phenotyped for beneficial traits. Accessions with strong basal rot resistance and increased seedling vigour were identified along with associated markers. Abstract Conserving biodiversity is critical for safeguarding future crop production. Onion ( Allium cepa L.) is a globally important crop with a very large (16 Gb per 1C) genome which has not been...
Lobster phyllosoma are known to associate with large cnidarian medusae; however, direct quantitative observations are difficult because gelatinous zooplankton are extremely fragile, and the phyllosoma easily detach from their host when sampled by plankton nets. We provide the first large scale quantitative information of the distribution of this association using an in situ imaging system, with synoptic measurements of water c...
Manganese transport is essential for N 2 ‐fixation by Rhizobium leguminosarum in bacteroids from galegoid but not phaseoloid nodulesNARA Subscribed
Summary Rhizobium leguminosarum has two high‐affinity Mn 2+ transport systems encoded by sitABCD and mntH . In symbiosis, sitABCD and mntH were expressed throughout nodules and also strongly induced in Mn 2+ ‐limited cultures of free‐living cells. Growth of a sitA mntH double mutant was severely reduced under Mn 2+ limitation and sitA and mntH single mutants were more sensitive to oxidative stress. The double sitA mntH mutant...
Mainstreaming the social sciences in conservationNARA Subscribed
Despite broad recognition of the value of social sciences and increasingly vocal calls for better engagement with the human element of conservation, the conservation social sciences remain misunderstood and underutilized in practice. The conservation social sciences can provide unique and important contributions to society's understanding of the relationships between humans and nature and to improving conservation practice and...