An adult female striped burrfish from a public display aquarium, mixed species recirculating system presented for an exophytic yellow–orange mass on the dorsal head suggestive of neoplasia. The mass was surgically excised twice, adding cryosurgical ablation during the second procedure, but recurred both times post‐operatively. After approximately 9 months, euthanasia was elected due to lesion progression. Histopathologic evalu...

Background In vitro cell culture models are widely used in cancer drug development. However, traditional two-dimensional (2D) models do not replicate the complex characteristics of the tumour microenvironment. Three-dimensional (3D) culture models have been used to prepare cell spheroids that are increasingly used in drug screening and evaluation due to their greater capacity to mimic tumour properties. Area covered This revie...