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Journal of Pharmacokinetics and Pharmacodynamics · 2025 · Vol. 52 · Issue 6 · Springer
Model-informed drug development (MIDD) is a framework that utilizes quantitative modeling and simulation methods to integrate nonclinical and clinical data, as well as prior knowledge, to inform drug development and regulatory decision-making. This scoping review examines the current MIDD landscape with a focus on pharmacometrics. It will clarify essential MIDD concepts and provide a taxonomy of terms. Additionally, it will ev...