The lima bean ( Phaseolus lunatus L.) is a legume of high agronomic and nutritional importance, particularly for smallholder farming in northeastern Brazil. The breeding program at the Federal University of Piauí (UFPI, Brazil) developed lines from biparental crosses, selecting traits of agronomic relevance for crop improvement, such as determinate growth habit, earliness, and yield. This study evaluated the genetic diversity...

Background Cardiovascular diseases are the leading cause of death worldwide. An important mechanism involved is the disruption in protein homeostasis by overactivation of the classical axis of the renin-angiotensin system. The counterregulatory axis counteracts these effects; however, the MrgD receptor has recently been described, and its effects are unknown. Thus, this study aims to evaluate the impact of MrgD deficiency on c...

This study assessed whether combining the aminoglycoside gentamicin with caffeine enhances antimicrobial efficacy in a murine typhoid model. We infected murine peritoneal macrophages in vitro with Salmonella enterica serovar Typhimurium and treated them for 24 h with non-toxic concentrations of caffeine (0.05–5 µg/ml) plus gentamicin (10 µg/ml). Subsequently, Swiss mice were orally challenged with S. Typhimurium and received d...

Previous study demonstrated that Hypnea cervicornis lectin (HCA) reduces inflammation and nociception via interaction with the lectin carbohydrate-binding site, modulating gene expression of the interleukins IL-1β, TNF-α and of iNOS. This study evaluated the effect of HCA in the rat model of arthritis induced by zymosan in the tibiotarsal joint and the involvement of macrophage-derived mediators. In vitro, macrophages were sti...

Cetaceans are highly adapted marine mammals whose survival depends on precise auditory and echolocation systems. Therefore, disease processes affecting these systems, including parasitic infections pose significant morbidity and may result in stranding and death. Here, we describe the pathologic and parasitological findings in an adult, male melon-headed whale ( Peponocephala electra ) stranded dead on the Brazilian coast. The...

The anesthetic management of female dogs with mammary neoplasia, usually classified as ASA II and undergoing invasive procedures such as mastectomy and ovariohysterectomy, requires effective sedation and anesthetic stability due to the increased anesthetic risk associated with advanced age and underlying disease. In this context, this study aimed to evaluate the sedative effects and reduction in anesthetic requirements of a fu...

Morningglory species ( Ipomoea spp.) are important weeds in Brazilian agriculture, particularly in non-burning sugarcane farming system. The fungus Cercospora aff. canescens has been selected as potential mycoherbicide; however, inoculum production is considered a challenge. The purpose of this study was to define and optimize culture conditions for biomass and spore yield of Cercospora aff. canescens CMAA 1444 in submerged fe...

Agricultural expansion, combined with poor soil management, can result in soil degradation, erosion, and nutrient depletion. Agroforestry systems (AFS) are sustainable alternatives that promote soil health, conserve biodiversity, and increase productive resilience. This study aimed to evaluate the physical, chemical, and biological attributes of soils under AFS and forests (FOR) in Paraty, Rio de Janeiro, located in the Atlant...