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First report of a species of Senga (Cestoda: Bothriocephalidae) in commercial Betta splendens (Actinopterygii: Osphronemidae) in BrazilNARA Subscribed
Species of the genus Senga comprise a group of bothriocephalidean cestodes that predominantly parasitize freshwater teleost fishes, causing severe histopathological alterations due to scolex attachment to the digestive tract or obstruction of the intestinal lumen. The Siamese fighting fish Betta splendens is the type-host of Senga besnardi , the type species of the genus known only from the original description. Despite the im...
Agricultural expansion, combined with poor soil management, can result in soil degradation, erosion, and nutrient depletion. Agroforestry systems (AFS) are sustainable alternatives that promote soil health, conserve biodiversity, and increase productive resilience. This study aimed to evaluate the physical, chemical, and biological attributes of soils under AFS and forests (FOR) in Paraty, Rio de Janeiro, located in the Atlant...
Unveiling the Viral Landscape in Gastric CancerNARA Subscribed
The present study aimed to comprehensively characterize the cancer-associated virome in patients with gastric cancer. A total of 452 samples were analyzed, including 226 tumor tissues and 202 peritumoral tissues from patients undergoing surgical resection, alongside 24 normal gastric mucosa samples obtained via endoscopy from individuals without cancer. RNA was extracted, libraries were prepared, and paired-end sequencing was...
The genus Amblyomma koch, 1844 contains approximately 138 species, which are mainly distributed in the Afrotropical, Oriental, Neotropical and Australasian zoogeographic regions. This is an important group of arthropod vectors responsible for transmitting a wide range of etiological agents that cause infections and diseases in humans and animals, and is therefore of great interest to public and veterinary health.This study des...
The emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a critical threat to global public health due to limited therapeutic options. This situation is magnified by CRKP strains with elevated virulence. This study aimed to characterize the virulome, resistome, and bla KPC genetic context of CRKP strains exhibiting increased virulence from hospital-associated infections in southeastern Brazil, focusing on their...
Integrated Computational and Experimental Discovery of Antitumoral Peptides Targeting Luminal A and Triple-Negative Breast CancerNARA Subscribed
Background Breast cancer remains one of the leading causes of cancer-related mortality worldwide, highlighting the need for more selective and effective therapies. This study aimed to identify and validate novel anticancer peptides targeting Luminal A (MCF-7) and triple-negative (MDA-MB-231) breast cancer subtypes using an integrated in silico and in vitro approach. Methods Overexpressed proteins in each cell line were identif...
Aim We investigate the distribution of dispersal modes — endozoochory (via animal ingestion), synzoochory (via animal seed accumulation) and anemochory (via wind)—and seed mass of woody plants across Brazilian ecosystems, testing whether their relative abundance in local plant communities could be predicted by climate, edaphic factors and dispersal agents (e.g., the main vectors moving seeds). We expected climate to be the mai...