Chronic kidney disease (CKD) and diabetic kidney disease (DKD) are major public health problems, and their burden is growing relentlessly with the aging of the global population. Their early recognition is now a public health priority, and there is an unmet need for the identification of specific biomarkers in minimally invasive or non-invasive samples. Mitochondrial dysfunction plays a pivotal role in the development and prog...

Precipitation is the most important element of the water cycle and an indispensable element of water resources management. This paper’s aim is to model the monthly precipitation in 8 precipitation observation stations in the province of Hamadan, Iran. The effects and role of different feature weights pre-processing methods (Weight by deviation, Weight by PCA, Weight by correlation and Weight by Support Vector Machine) on artif...

Preeclampsia (PE) is a major complication of pregnancy with partially elucidated pathophysiology. Placental mitochondrial dysfunction has been increasingly studied as major pathomechanism in both early- and late-onset PE. Impairment of mitochondrial respiration in platelets has recently emerged as a peripheral biomarker that may mirror organ mitochondrial dysfunction in several acute and chronic pathologies. The present study...