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Free Fatty acid-induced disruption of hepatic vitamin D metabolism impairs bone homeostasis in an in vitro 3D human liver–bone modelNARA Subscribed
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a systemic condition associated with compromised bone integrity. Emerging evidence suggests that disturbances in hepatic vitamin D metabolism may contribute to these skeletal impairments. However, the hepatic mechanisms driving bone deterioration remain poorly defined. This study aimed to establish a human 3D in vitro model of MASLD and demonstrate that hepati...
SNAPSHOT USA 2024: Year 6 of the Coordinated National Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multi‐contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of speci...
The Effects of Different Light Spectra, UV and Extreme Temperature on the Physiology of Endosymbiotic Jellyfish Cassiopea andromedaNARA Subscribed
The endosymbiotic jellyfish Cassiopea andromeda represents a yet untapped marine species that could be targeted as a new source for bioproducts, including food and feed. Also, the potential use of contained valuable ingredients, such as carotenoids and other antioxidants, under controlled aquaculture conditions might be a particularly promising pathway. However, this requires close knowledge about physiology and culture condit...
Citizen Science in der Zeckenforschung — ein ErfolgsmodellNARA Subscribed
Ticks are medically relevant as vectors for multiple pathogens. Besides Ixodes ricinus , which occurs ubiquitously throughout Europe, the meadow tick Dermacentor reticulatus is increasingly common. We used a Citizen Science approach to demonstrate the recent Germany-wide range expansion of this tick species, and to investigate its infection rate with Babesia canis , a canine pathogen causing potentially fatal disease. Travelli...
Establishment of a human 3D in vitro liver-bone model as a potential system for drug toxicity screeningNARA Subscribed
Drug toxicity is an important cause of chronic liver damage, which in the long term can lead to impaired bone homeostasis through an imbalance in the liver-bone axis. For instance, non-steroidal anti-inflammatory drugs ( e.g., diclofenac), which are commonly used to control pain during orthopaedic interventions, are known to reduce bone quality and are the most prevalent causes of drug-induced liver damage. Therefore, we used...
SNAPSHOT USA 2019–2023: The First Five Years of Data From a Coordinated Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multicontributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of specie...
Sea grape (Caulerpa lentillifera) aquaculture in Van Phong Bay, Viet Nam: Evaluation of the post-harvest qualityNARA Subscribed
Caulerpa lentillifera, known as `sea grapes´ or `green caviar´, is increasingly in demand as a sea vegetable for human consumption. The seaweed is cultivated in ponds in the Khánh Hòa province in Van Phong Bay, Viet Nam, during the dry season (March-October). The harvested sea grape fronds are graded into different qualities based on their physical characteristics for retail on the local market or for export. Based on systemat...
Seaweeds are a major contributor to global marine aquaculture production, with the biomass being mainly used, among others, for human nutrition, pharmaceutics, and cosmetics. However, green seaweeds are severely underrepresented, compared to red and brown macroalgae. Caulerpa lentillifera (known as “sea grapes” or “green caviar”) is an edible, green seaweed with a distinctive texture and various nutritional benefits. In this r...
Introduction The up-side down jellyfish Cassiopea andromeda represents a yet untapped marine species that could be targeted as a new source for functional ingredients, such as natural pigments and antioxidants. Since C. andromeda hosts endosymbiotic dinoflagellates, this jellyfish contains peridinin pigments, which are linked with high antioxidant capacities and many other health-promoting properties. This study investigates t...
The interest in edible sea grapes ( Caulerpa lentillifera ) is increasing due to their potentially beneficial effect on human health. This macroalga, already used for direct and indirect human consumption, is grown in aquacultures in Vietnam and The Philippines. Here, the edible fronds of sea grapes were examined for their antioxidant activity (AOA) at light intensities from 140 to 300 µmol photons m −2 s −1 and compared to co...
Cultured and packed sea grapes (Caulerpa lentillifera): effect of different irradiances on photosynthesisNARA Subscribed
The green macroalga Caulerpa lentillifera (sea grapes, green caviar) is a promising source for future nutrition due to its beneficial composition for human consumption. It is cultured in tidal ponds, mainly in Vietnam and the Philippines, and stored for shipment and retail in plastic containers, like polystyrene (PS) and polyethylene terephthalate (PET), exhibiting different properties. This study investigates the influence of...
E-vapor aerosols do not compromise bone integrity relative to cigarette smoke after 6-month inhalation in an ApoE–/– mouse modelNARA Subscribed
Cigarette smoke (CS) exposure is one of the leading risk factors for human health. Nicotine-containing inhalable products, such as e-cigarettes, can effectively support tobacco harm reduction approaches. However, there are limited comparative data on the effects of the aerosols generated from electronic vapor products (e-vapor) and CS on bone. Here, we report the effects of e-vapor aerosols and CS on bone morphology, structure...
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