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Parkinson’s Disease–Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein ClearanceNARA Subscribed
Parkinson’s disease (PD) is a neurodegenerative, progressive disease without a cure. To prevent PD onset or at least limit neurodegeneration, a better understanding of the underlying cellular and molecular disease mechanisms is crucial. Mutations in the leucine-rich repeat kinase 2 ( LRRK2 ) gene represent one of the most common causes of familial PD. In addition, LRRK2 variants are risk factors for sporadic PD, making LRRK2 a...
Pinestraw harvesting is an important industry in the southeastern United States. There is a need to understand how fertilization can be used efficiently to sustain or increase long-term pinestraw yields and avoid adverse environmental consequences. The effects of fertilization on needlefall nutrient concentrations, pinestraw yields, and nutrient removals on soils with contrasting soil nutrient sorption potential (Entisol vs. U...
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