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The vasoprotective role of IGF-1 signaling in the cerebral microcirculation: prevention of cerebral microhemorrhages in agingNARA Subscribed
Aging is closely associated with various cerebrovascular pathologies that significantly impact brain function, with cerebral small vessel disease (CSVD) being a major contributor to cognitive decline in the elderly. Consequences of CSVD include cerebral microhemorrhages (CMH), which are small intracerebral bleeds resulting from the rupture of microvessels. CMHs are prevalent in aging populations, affecting approximately 50% of...
Synchronous genetic turnovers across Western Eurasia in Late Pleistocene collared lemmingsNARA Subscribed
Recent palaeogenetic studies indicate a highly dynamic history in collared lemmings ( Dicrostonyx spp.), with several demographical changes linked to climatic fluctuations that took place during the last glaciation. At the western range margin of D. torquatus , these changes were characterized by a series of local extinctions and recolonizations. However, it is unclear whether this pattern represents a local phenomenon, possib...
The history of sturgeon in the Baltic SeaNARA Subscribed
Aim Migrants of the Atlantic sturgeon, Acipenser oxyrinchus , from North America are thought to have founded the Baltic sturgeon population during the Little Ice Age around 1200 years ago, replacing the European sturgeon, Acipenser sturio . To test this hypothesis and to further elucidate the colonization of the Baltic Sea by A. oxyrinchus , we carried out DNA analyses of ancient and contemporary populations of both species. L...
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