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Key factors of the deranged antiviral response in elderly patients with COVID-19: a machine-learning analysisNARA Subscribed
Age is a well-known risk factor to develop severe viral respiratory infections, including severe COVID-19. This study aimed to identify the biological alterations linked to severe disease in elderly patients with COVID-19. For this purpose, we employed a derivation cohort with 450 SARS-CoV-2 infected and unvaccinated patients admitted to hospital wards and a validation cohort with 244 SARS-CoV-2 infected and unvaccinated patie...
The biomedical engineer’s pledge: overview and contextNARA Subscribed
Although biomedical engineering (BME) is a profession with ethical responsibilities comparable to those in medicine, it has, until now, lacked a counterpart to the Hippocratic Oath. While professional societies have established codes of ethics for biomedical engineers, these documents lack the symbolic and ceremonial significance of an oath or pledge. By contrast, the recitation of the Hippocratic Oath, or its modern version,...
A trait‐based approach to assess niche overlap and functional distinctiveness between non‐indigenous and native speciesNARA Subscribed
Our understanding of the community assembly processes acting on non‐indigenous species (NIS), as well as the relationship with native species is limited, especially in marine ecosystems. To overcome this knowledge gap we here develop a trait‐based approach based on the functional distinctiveness metric to assess niche overlap between NIS and native species, using high‐resolution data on benthic invertebrate communities in the...
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