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NARA Subscribed1
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Springer Nature1
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GeroScience1
Publication Year
20251
Ariel Nevarez results 1 · Newest (Page 1/1, per page 25)
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Author: Ariel Nevarez ×Clear All Filters
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GHSR suppression in neurons protects against aging-associated metabolic and cognitive impairmentsNARA Subscribed
GeroScience · 2025 · Springer
Hongying Wang; Chia-Shan Wu; Danilo Landrock; Ariel Nevarez; Shanrun Liu; Anna Thalacker-Mercer; Yanfeng Zhang; Jamie I. Baum; Sunja Kim; Bingzhong Xue; Yuxiang Sun
Aging is accompanied by progressive declines in metabolic and cognitive functions. Growth hormone secretagogue receptor (GHSR), a receptor for the gut hormone ghrelin, is highly expressed in neurons and plays a crucial role in metabolic regulation. We previously reported that aged global GHSR-ablated mice are lean and insulin-sensitive, and that neuronal GHSR-deleted mice ( Syn1‐cre;Ghsr f/f ) completely prevent diet‐induced o...
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