Summary The structure of the extant transcriptional control network of the TOL plasmid pWW0 born by Pseudomonas putida mt‐2 for biodegradation of m‐ xylene is far more complex than one would consider necessary from a mere engineering point of view. In order to penetrate the underlying logic of such a network, which controls a major environmental cleanup bioprocess, we have developed a dynamic model of the key regulatory node f...