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NARA Subscribed2
Publisher
Springer Nature2
Journal
Angiogenesis2
Publication Year
20231
20171
Axel Bex results 2 · Newest (Page 1/1, per page 25)
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Author: Axel Bex ×Clear All Filters
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Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergyNARA Subscribed
Angiogenesis · 2023 · Vol. 26 · Issue 2 · Springer
Patrycja Nowak-Sliwinska; Judy R. van Beijnum; Christian J. Griffioen; Zowi R. Huinen; Nadine Grima Sopesens; Ralph Schulz; Samir V. Jenkins; Ruud P. M. Dings; Floris H. Groenendijk; Elisabeth J. M. Huijbers; Victor L. J. L. Thijssen; Eric Jonasch; Florry A. Vyth-Dreese; Ekaterina S. Jordanova; Axel Bex; René Bernards; Tanja D. de Gruijl; Arjan W. Griffioen
Purpose Ongoing angiogenesis renders the tumor endothelium unresponsive to inflammatory cytokines and interferes with adhesion of leukocytes, resulting in escape from immunity. This process is referred to as tumor endothelial cell anergy. We aimed to investigate whether anti-angiogenic agents can overcome endothelial cell anergy and provide pro-inflammatory conditions. Experimental design Tissues of renal cell carcinoma (RCC)...
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Antiangiogenic therapy combined with immune checkpoint blockade in renal cancerNARA Subscribed
Angiogenesis · 2017 · Vol. 20 · Issue 2 · Springer
Teele Kuusk; Laurence Albiges; Bernard Escudier; Nikolaos Grivas; John Haanen; Thomas Powles; Axel Bex
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