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A bovine in vitro platform improves species comparability of mitochondrial apoptosis drug-response readoutsNARA Subscribed
Species differences in mitochondrial apoptosis control can bias cytotoxicity endpoints and hazard-relevant mechanistic inference in preclinical test systems that rely on intrinsic-apoptosis readouts. We benchmarked steady-state localization and outer mitochondrial membrane (OMM) assemblies of the BCL-2 effectors BAX and BAK across mammals and combined this with functional apoptosis assays in bovine hepatocytes. Across species,...
Dominance and rarity in tree communities across the globe: Patterns, predictors and threatsNARA Subscribed
Aim Ecological and anthropogenic factors shift the abundances of dominant and rare tree species within local forest communities, thus affecting species composition and ecosystem functioning. To inform forest and conservation management it is important to understand the drivers of dominance and rarity in local tree communities. We answer the following research questions: (1) What are the patterns of dominance and rarity in tree...
Wind dispersed tree species have greater maximum heightNARA Subscribed
Aim We test the hypothesis that wind dispersal is more common among emergent tree species given that being tall increases the likelihood of effective seed dispersal. Location Americas, Africa and the Asia‐Pacific. Time period 1970–2020. Major taxa studied Gymnosperms and Angiosperms. Methods We used a dataset consisting of tree inventories from 2821 plots across three biogeographic regions (Americas, Africa and Asia‐Pacific),...
The potential of cover crops to increase soil organic carbon storage in German croplandsNARA Subscribed
Aims Soil organic carbon (SOC) stocks of croplands can be enhanced by targeted management, which boosts soil fertility and contributes to climate change mitigation. One SOC sequestration option is adopting cover crops. The aim of this study was to quantify the SOC sequestration potential of cover crops in Germany. Methods We simulated SOC scenarios on 1,267 cropland sites with site-specific management data using an SOC model e...
Microplastics (MPs) are synthetic polymer pieces with a size of less than 5 mm that are ubiquitous in the marine environment. They have been recently detected in several wild species and sea products. An indispensable condiment in human food is marine salt that is produced from seawater. Since toxicity studies report potential health impacts when plastic debris is ingested, more attention must be paid to the MP contamination o...
Needlestick injuries: a density-equalizing mapping and socioeconomic analysis of the global researchNARA Subscribed
Background Needlestick injuries have caused a deleterious effect on the physical and mental health of millions of health-care workers over the past decades, being responsible for occupational infections with viruses such as HIV or hepatis C. Despite this heavy burden of disease, no concise studies have been published on the global research landscape so far. Methods We used the New Quality and Quantity Indices in Science platfo...
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