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Pandemic Vibrio cholerae and the Environmental Reservoir Hypothesis—Outstanding Questions Central to Global Cholera ControlNARA Subscribed
Despite global cholera cases rising to more than 560,000 in 2024, there remains no consensus on a fundamental aspect of cholera epidemiology: whether pandemic Vibrio cholerae forms long‐term environmental reservoirs which become the source of future outbreaks. This knowledge gap prevents optimal disease forecasting, resource allocation and outbreak response in a variety of at‐risk settings, from places experiencing annual chol...
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